What are the potential risks of taking high-dose biotin supplements. How can biotin interfere with medical tests. Why should you consult a healthcare provider before starting biotin supplementation. What are the recommended dosages of biotin for different age groups. How long does it take to see results from biotin supplementation.

Understanding Biotin: Uses, Benefits, and Potential Risks

Biotin, also known as vitamin B7, is a water-soluble vitamin that plays a crucial role in various bodily functions. It helps the body metabolize fats, carbohydrates, and proteins, contributing to overall health and well-being. While biotin is naturally present in many foods, some people turn to supplements, particularly high-dose options like biotin 5000 mcg, to address perceived deficiencies or improve hair, skin, and nail health.

However, as with any supplement, it’s essential to understand the potential side effects and risks associated with high-dose biotin intake. This article will explore six unexpected and potentially dangerous side effects of taking biotin 5000 mcg, as well as provide valuable information on its proper use and considerations.

The Alarming Impact of Biotin on Medical Test Results

One of the most concerning side effects of high-dose biotin supplementation is its interference with various medical tests. This can lead to false results, potentially compromising diagnosis and treatment decisions.

How does biotin affect medical tests? Biotin can interfere with tests that use biotin-streptavidin technology, which is common in many laboratory assays. This interference can cause falsely high or low results, depending on the specific test.

Which medical tests are most affected by biotin? Some of the tests that can be impacted include:

• Thyroid function tests
• Cardiac troponin levels (used to diagnose heart attacks)
• Hormone tests (e.g., testosterone, estradiol)
• Vitamin D levels
• Cancer markers

To mitigate this risk, it’s crucial to inform your healthcare provider about any biotin supplements you’re taking before undergoing medical tests. In some cases, you may need to temporarily discontinue biotin use before testing to ensure accurate results.

Gastrointestinal Distress: A Common but Overlooked Side Effect

While often considered mild, gastrointestinal issues can be a significant concern for some individuals taking high-dose biotin supplements.

What gastrointestinal symptoms can biotin cause? Common complaints include:

• Nausea
• Abdominal cramps
• Diarrhea
• Indigestion

Why do these symptoms occur? High doses of biotin can overwhelm the body’s ability to process the vitamin efficiently, leading to digestive discomfort. Additionally, some individuals may be more sensitive to biotin or the supplement’s inactive ingredients.

To minimize gastrointestinal side effects, consider starting with a lower dose of biotin and gradually increasing it as tolerated. Taking the supplement with food may also help reduce digestive issues.

Skin Reactions: When Beauty Supplements Backfire

Ironically, while many people take biotin supplements to improve skin health, high doses can sometimes lead to adverse skin reactions.

What types of skin reactions can occur with biotin supplementation? Some individuals may experience:

• Acne breakouts
• Rashes
• Itching
• Hives

Why do these skin reactions happen? The exact mechanism is not fully understood, but it’s believed that high doses of biotin may alter the balance of vitamins and minerals in the body, potentially affecting skin health. Additionally, some people may be allergic to biotin or other ingredients in the supplement.

If you experience any skin reactions while taking biotin, discontinue use and consult your healthcare provider. They can help determine if the reaction is related to the supplement and recommend appropriate alternatives or treatments.

Interactions with Medications: A Hidden Danger

High-dose biotin supplements can interact with various medications, potentially altering their effectiveness or increasing the risk of side effects.

Which medications are most likely to interact with biotin? Some notable interactions include:

• Anticonvulsants (e.g., carbamazepine, phenytoin)
• Antibiotics (e.g., tetracyclines)
• Antidepressants
• Cholesterol-lowering medications (statins)

How do these interactions occur? Biotin can affect the absorption, metabolism, or excretion of certain medications. In some cases, it may also compete for the same metabolic pathways, altering the drug’s effectiveness.

To avoid potential interactions, always inform your healthcare provider and pharmacist about all supplements you’re taking, including biotin. They can assess potential risks and adjust your medication regimen if necessary.

Nutrient Imbalances: The Double-Edged Sword of Supplementation

While biotin supplementation aims to address deficiencies, high doses can paradoxically lead to imbalances in other nutrients.

How can biotin cause nutrient imbalances? High doses of biotin may:

• Interfere with the absorption of other B vitamins
• Alter mineral metabolism, particularly zinc and magnesium
• Affect the balance of other fat-soluble vitamins

What are the potential consequences of these imbalances? Nutrient imbalances can lead to various health issues, including:

• Weakened immune function
• Impaired cognitive performance
• Reduced energy levels
• Compromised bone health

To minimize the risk of nutrient imbalances, consider taking a balanced multivitamin instead of high-dose individual supplements. If you choose to take biotin, opt for a moderate dose and ensure you’re maintaining a varied, nutrient-rich diet.

Masking Vitamin B12 Deficiency: A Serious Oversight

One of the most concerning side effects of high-dose biotin supplementation is its ability to mask vitamin B12 deficiency, potentially delaying diagnosis and treatment of this serious condition.

How does biotin mask B12 deficiency? High levels of biotin can interfere with blood tests used to diagnose vitamin B12 deficiency, leading to falsely normal or elevated results. This can prevent proper diagnosis and treatment of B12 deficiency, which can have severe neurological consequences if left untreated.

What are the symptoms of vitamin B12 deficiency? Common signs include:

• Fatigue
• Weakness
• Numbness or tingling in extremities
• Cognitive difficulties
• Anemia

If you’re taking high-dose biotin supplements and experience any of these symptoms, it’s crucial to inform your healthcare provider. They may recommend discontinuing biotin use before B12 testing to ensure accurate results.

Proper Usage and Dosage Guidelines for Biotin Supplementation

To minimize the risk of side effects and maximize the potential benefits of biotin supplementation, it’s essential to follow proper usage and dosage guidelines.

What is the recommended daily allowance (RDA) for biotin? The RDA varies by age and life stage:

• Infants 0-6 months: 5 mcg
• Infants 7-12 months: 6 mcg
• Children 1-3 years: 8 mcg
• Children 4-8 years: 12 mcg
• Children 9-13 years: 20 mcg
• Adolescents 14-18 years: 25 mcg
• Adults 19+ years: 30 mcg
• Pregnant women: 30 mcg
• Breastfeeding women: 35 mcg

Why do some supplements contain much higher doses? Many biotin supplements, including the 5000 mcg formulation, far exceed the RDA. These high doses are often marketed for hair, skin, and nail health, although scientific evidence supporting these claims is limited.

How should biotin supplements be taken? For optimal absorption and to minimize side effects:

• Take biotin with food to reduce the risk of gastrointestinal discomfort
• If using liquid biotin, measure carefully using the provided dropper or a medicine dose-measuring device
• Be consistent with your dosing schedule
• Allow 3-6 months to see potential improvements in hair or nail condition

Is it possible to overdose on biotin? While biotin is water-soluble and excess is typically excreted in urine, very high doses can lead to the side effects discussed in this article. Always follow the recommended dosage on the product label or as advised by your healthcare provider.

Special Considerations for Biotin Supplementation

Certain groups may need to exercise extra caution when considering biotin supplementation:

Who should be particularly careful with biotin supplements?

• Pregnant and breastfeeding women: Consult a healthcare provider before starting any new supplement regimen
• Individuals with pre-existing medical conditions: Biotin may interact with certain conditions or treatments
• People taking multiple medications: The risk of drug interactions increases with polypharmacy
• Older adults: Age-related changes in metabolism may affect biotin processing

When should you avoid biotin supplements altogether? You should not use biotin if you have a known allergy to the vitamin or any ingredients in the supplement formulation. Additionally, if you experience severe side effects, discontinue use and consult your healthcare provider.

Alternatives to High-Dose Biotin Supplementation

For those concerned about the potential side effects of high-dose biotin supplements, there are several alternatives to consider.

What are some natural sources of biotin? Biotin can be found in various foods, including:

• Egg yolks
• Nuts (especially almonds and peanuts)
• Seeds (such as sunflower seeds)
• Sweet potatoes
• Spinach
• Broccoli
• Salmon
• Avocados

Are there other supplements that can support hair, skin, and nail health? Some alternatives to consider include:

• Collagen peptides
• Omega-3 fatty acids
• Vitamin C
• Zinc
• Silica

How can you improve hair, skin, and nail health without supplements? Lifestyle factors play a crucial role in overall health and appearance. Consider:

• Maintaining a balanced, nutrient-rich diet
• Staying hydrated
• Getting adequate sleep
• Managing stress
• Protecting your skin from sun damage
• Using gentle, non-irritating hair and skin care products

The Importance of Professional Guidance

Given the potential risks and complexities associated with high-dose biotin supplementation, seeking professional guidance is crucial.

Why is it important to consult a healthcare provider before starting biotin supplements? A healthcare professional can:

• Assess your individual needs and potential risks
• Recommend appropriate dosages based on your health status
• Evaluate potential interactions with medications or medical conditions
• Monitor for side effects and adjust treatment as needed
• Provide guidance on alternative approaches to address your health concerns

What questions should you ask your healthcare provider about biotin supplementation?

• Is biotin supplementation appropriate for my specific health concerns?
• What dosage would be safe and effective for me?
• Are there any potential interactions with my current medications or medical conditions?
• How long should I take the supplement, and what results can I realistically expect?
• Are there any specific side effects I should watch out for?
• What alternatives might be suitable if biotin isn’t the best option for me?

Monitoring and Managing Biotin Supplementation

If you decide to proceed with biotin supplementation, it’s essential to monitor your progress and be aware of potential issues that may arise.

How can you track the effectiveness of biotin supplementation? Consider:

• Taking “before” photos of your hair, skin, or nails for comparison
• Keeping a journal to note any changes in appearance or overall health
• Regularly measuring hair growth or nail strength
• Scheduling follow-up appointments with your healthcare provider

What signs indicate that you should discontinue biotin use? Be alert for:

• Persistent gastrointestinal discomfort
• Skin reactions or breakouts
• Unexpected changes in energy levels or overall health
• Abnormal lab results during routine medical check-ups

How often should you reassess your need for biotin supplementation? It’s advisable to review your supplement regimen with your healthcare provider at least annually or more frequently if you experience any side effects or changes in your health status.

The Future of Biotin Research and Supplementation

As interest in biotin supplementation continues to grow, ongoing research may provide new insights into its benefits and risks.

What areas of biotin research are currently being explored?

• The effectiveness of biotin for specific health conditions
• Optimal dosages for various purposes
• Long-term effects of high-dose supplementation
• Potential applications in medical treatments
• Interactions with other nutrients and medications

How might future findings impact biotin supplementation practices? As more research becomes available, we may see:

• Updated dosage recommendations
• New formulations or delivery methods
• Improved testing methods to avoid biotin interference
• Enhanced understanding of biotin’s role in overall health
• More targeted applications for specific health concerns

In conclusion, while biotin supplementation can offer potential benefits, it’s crucial to approach high-dose formulations like biotin 5000 mcg with caution. By understanding the unexpected and potentially dangerous side effects, following proper usage guidelines, and seeking professional guidance, you can make informed decisions about whether biotin supplementation is right for you. Remember that a balanced diet, healthy lifestyle, and personalized approach to supplementation are key to achieving optimal health and well-being.

Biotin Uses, Side Effects & Warnings

Generic name: biotin (oral) [ BYE-oh-tin ]
Brand names: Appearex, Cyto B7, Hair, Skin & Nails, Hair,
… show all 8 brands
Skin, Nails, Vitafusion Biotin Extra Strength Gummy

Dosage forms: oral capsule (5 mg; 5000 mcg), oral liquid (5 mg/mL), oral tablet (10 mg; 1000 mcg; 2.5 mg; 300 mcg), oral tablet, disintegrating (5000 mcg)
Drug class: Vitamins

Medically reviewed by Drugs.com on Nov 28, 2022. Written by Cerner Multum.

What is biotin?

Biotin is a form of vitamin B found in foods. Biotin helps the body break down fats, carbohydrates, and proteins.

Biotin has been used in alternative medicine as a likely effective aid in treating or preventing biotin deficiency. Biotin deficiency can be caused by malnutrition, rapid weight loss, long-term tube feeding, and other medical conditions.

Biotin has also been used to treat seborrhea (skin rash) in babies. However, research has shown that biotin may not be effective in treating this condition.

Other uses not proven with research have included treating brittle nails or thinning hair, diabetes, nerve pain, and other conditions.

It is not certain whether biotin is effective in treating any medical condition. Medicinal use of this product has not been approved by the FDA. Biotin should not be used in place of medication prescribed for you by your doctor.

Biotin is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Biotin may also be used for purposes not listed in this product guide.

Warnings

Follow all directions on the product label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use this product if you are allergic to biotin.

Before using biotin, talk to your healthcare provider. Your dose needs may be different:

Ask a doctor before using biotin if you are pregnant or breastfeeding. Your dose needs may be different during pregnancy or while you are nursing.

Do not give any herbal/health supplement to a child without medical advice.

How should I take biotin?

When considering the use of herbal supplements, seek the advice of your doctor. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements.

If you choose to use biotin, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than is recommended on the label.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Biotin can cause false results with certain medical tests. Tell any doctor who treats you that you are using biotin.

The recommended dietary allowance of biotin increases with age. Follow your healthcare provider’s instructions. You may also consult the Office of Dietary Supplements of the National Institutes of Health, or the U.S. Department of Agriculture (USDA) Nutrient Database (formerly “Recommended Daily Allowances”) listings for more information.

It may take 3 to 6 months before the condition of your hair or nails improves.

Call your doctor if the condition you are treating with biotin does not improve, or if it gets worse while using this product.

After you stop using biotin, your nails will likely return to their original condition within 6 to 9 months.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra biotin to make up the missed dose.

What happens if I overdose?

Since biotin is a water-soluble vitamin, an overdose is unlikely to occur.

What should I avoid while taking biotin?

Follow your healthcare provider’s instructions about any restrictions on food, beverages, or activity.

Biotin side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Common side effects may include upset stomach or diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect biotin?

Taking certain medicines can lower your blood levels of biotin, which could affect your biotin dose needs. Ask a doctor or pharmacist before using biotin with any other medications, especially:

• carbamazepine;

• phenobarbital;

• phenytoin; or

• primidone.

This list is not complete. Other drugs may affect biotin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

More about biotin

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• Patient Information
• Biotin Chewable Tablets
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Other brands

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Further information

• Consult with a licensed healthcare professional before using any herbal/health supplement. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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Health Benefits, Side Effects, Uses, Dose & Precautions

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Suzuki, Y., Yang, X., Aoki, Y., Kure, S., and Matsubara, Y. Mutations in the holocarboxylase synthetase gene HLCS. Hum.Mutat. 2005;26(4):285-290. View abstract.

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Sydenstricker, V. P., Singal, S. A., Briggs, A. P., Devaughn, N. M., and Isbell, H. PRELIMINARY OBSERVATIONS ON “EGG WHITE INJURY” IN MAN AND ITS CURE WITH A BIOTIN CONCENTRATE. Science 2-13-1942;95(2459):176-177. View abstract.

Tarmina, M. S. Self-selected diet of adult women with families. 1992;257.

Tong, L. Acetyl-coenzyme A carboxylase: crucial metabolic enzyme and attractive target for drug discovery. Cell Mol.Life Sci 2005;62(16):1784-1803. View abstract.

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Vlaming, M. L., Lagas, J. S., and Schinkel, A. H. Physiological and pharmacological roles of ABCG2 (BCRP): recent findings in Abcg2 knockout mice. Adv.Drug Deliv.Rev. 1-31-2009;61(1):14-25. View abstract.

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Wilson, C. J., Myer, M., Darlow, B. A., Stanley, T., Thomson, G., Baumgartner, E. R., Kirby, D. M., and Thorburn, D. R. Severe holocarboxylase synthetase deficiency with incomplete biotin responsiveness resulting in antenatal insult in samoan neonates. J Pediatr. 2005;147(1):115-118. View abstract.

Wolf, B. Clinical issues and frequent questions about biotinidase deficiency. Mol.Genet.Metab 2010;100(1):6-13. View abstract.

Yoshikawa, K. [Vitamin and dermatology]. Nippon Rinsho 1999;57(10):2385-2389. View abstract.

Zempleni, J. and Mock, D. M. Advanced analysis of biotin metabolites in body fluids allows a more accurate measurement of biotin bioavailability and metabolism in humans. J Nutr. 1999;129(2S Suppl):494S-497S. View abstract.

Zempleni, J. and Mock, D. M. Utilization of biotin in proliferating human lymphocytes. J Nutr. 2000;130(2S Suppl):335S-337S. View abstract.

Zempleni, J. Uptake, localization, and noncarboxylase roles of biotin *. Annu.Rev Nutr. 2005;25:175-196. View abstract.

Zempleni, J., Green, G. M., Spannagel, A. W., and Mock, D. M. Biliary excretion of biotin and biotin metabolites is quantitatively minor in rats and pigs. J Nutr. 1997;127(8):1496-1500. View abstract.

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Zeng, W. Q., Al Yamani, E., Acierno, J. S., Jr., Slaugenhaupt, S., Gillis, T., MacDonald, M. E., Ozand, P. T., and Gusella, J. F. Biotin-responsive basal ganglia disease maps to 2q36.3 and is due to mutations in SLC19A3. Am.J Hum.Genet. 2005;77(1):16-26. View abstract.

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Baez-Saldana A, Zendejas-Ruiz I, Revilla-Monsalve C, et al. Effects of biotin on pyruvate carboxylase, acetyl-CoA carboxylase, propionyl-CoA carboxylase, and markers for glucose and lipid homeostasis in type 2 diabetic patients and nondiabetic subjects. Am J Clin Nutr 2004;79:238-43. View abstract.

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Biotin 5000mcg NOW 120 caps

Code: 73373

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Biotin 5000 mcg NOW 120 caps.
Now Biotin 5000mcg is nothing less than the well known water soluble vitamin B7. Biotin plays the role of a coenzyme in the metabolism of proteins, fats and carbohydrates, which makes it an extremely important element in the diet of athletes and people who monitor their health. Biotin also contributes to the activation of the transfer of ATP molecules, maintaining healthy hair, skin and nails.

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Biotin 10000 mcg WestPharm 60 caps.

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Biotin 10000 mcg WestPharm 60 caps.
Biotin / Biotin – a natural activator of metabolic processes that affects the percentage of body fat, muscle mass, body composition, as well as the condition of the skin, nails and hair. Regular intake of biotin increases the effectiveness of training for mass, endurance and relief, accelerates weight loss, restores youthfulness to hair and skin. For athletes practicing pharmaceutical support, biotin will help reduce the side effects of steroid cycles.

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Biotin 10000 mcg Swanson 60 caps

Code: 087614116860

Biotin 10000 mcg Swanson 60 caps.
Biotin performs a huge number of vital functions in the human body. But it is best known for its role in cellular energy production and tissue maintenance, which has made biotin supplements a favorite among athletes and beauty queens alike.

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Solgar Biotin 5000 mcg (50caps) – Sports Nutrition in Sevastopol Biotin also contributes to the production of energy in the body by converting food into energy; it is essential for the metabolism of proteins, carbohydrates and fats.

Suggested Use

As a dietary supplement for adults, take one (1) vegetable capsule daily, preferably with a meal, or as directed by a healthcare practitioner.

Other Ingredients

Microcrystalline cellulose, vegetable cellulose, vegetable magnesium stearate, silicon dioxide.

Free of gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavors, sweeteners, preservatives and colors.

SOLGAR is the world’s leading manufacturer of premium dietary supplements. Products are presented in 60 countries of the world: USA, UK, Italy, France, Spain, Holland, New Zealand, Israel, Russia, etc. well-being of people around the world.

Since 1947, SOLGAR has been producing premium 100% natural dietary supplements. To date, the assortment includes more than 500 items of vitamins, minerals, medicinal plants, amino acids, probiotics, complexes and special products.

SOLGAR’s complete plant is located in New Jersey, Leonia, USA.

The production is the most modern, both in terms of functionality and design.

The manufacturing facility complies with international GMP manufacturing, environmental protection and quality control standards.

SOLGAR guarantees quality at all stages of production and distribution.

Attention to detail and manufacturing has enabled SOLGAR to create its own quality standard, the SOLGAR Gold Standard™.

For SOLGAR, quality is not a random concept, it is a way of life, a way of thinking. Quality is at the heart of every process, at the heart of every product.

With its own research and development center, production site and distribution, SOLGAR guarantees the quality of products at all stages of production. In order to maintain the freshness of its products, SOLGAR releases it in small batches and manufactures it to its strict standards, which in most cases exceed the requirements of government regulators.

Quality Raw Materials
SOLGAR selects suppliers of the finest natural raw materials worldwide based on their many years of experience. SOLGAR requires suppliers to provide certificates of analysis to verify the authenticity and good quality of the supplied raw materials.

Research Center
The SOLGAR team of scientists is actively engaged in the search for new substances, review of scientific publications and current research. SOLGAR is an integral part of scientific research.

Quality control
Our own quality laboratory conducts comprehensive research at the initial stages of production, in the middle and at the stage of obtaining finished products, performing more than 130 control tests. The SOLGAR laboratory is the final authority for products to “bear” the SOLGAR gold label.

State of the art water treatment system
SOLGAR uses the latest water treatment system based on the reverse osmosis principle to achieve the highest degree of water purification.

Modern ventilation system
All the air circulating in production areas passes through numerous HEPA filters that trap 99.9% of airborne particles.

Cleanliness
After production of each batch, the equipment is completely dismantled and disinfected with gentle natural detergents that do not harm the environment.

KOSHER Certificate
SOLGAR is the first company to obtain the KOSHER Certificate for certain products.

Halal certified
SOLGAR is HALAL certified for some products.

Vegetarian capsules
SOLGAR is one of the first companies to use vegetarian capsules.

No Potential Allergens
In accordance with the Gold Standard™, SOLGAR avoids added sugar, salt, gluten, dairy ingredients. SOLGAR products are free from artificial colors and flavors, GMOs and other potential allergens.

Premium packaging
SOLGAR products are packaged in dark glass bottles, which best protect the products from fluctuations in temperature, light and humidity. Glass bottles can be recycled.

With its own research and development center, production site and distribution, SOLGAR guarantees the quality of its products at all stages of production.

SOLGAR uses innovative technology to provide customers with the highest quality products.

Molecular distillation is the only method known to remove toxic substances, namely heavy metal salts, from fish oil while maintaining the integrity of the fragile structure of omega-3 fatty acids.

Vacuum drying is a method of preserving in full all nutrients, trace elements, vitamins present in plant materials for a long time.

Full Potency Herbs is a method that allows you to use the potential of all plant materials, which ensures the preservation of a whole complex of biologically active substances.

PHYTO ₂ X System is a method of using natural antioxidants (mixtures of natural vitamins E, C, beta-carotene) as preservatives.

Active ingredient standardization is a method applied to herbal products to determine the exact concentration of the active ingredient in each capsule. SOLGAR standardized herbal products come in green glass bottles.

Chelated minerals is a special form of minerals in which they are better absorbed and at the same time have a minimal risk of causing unwanted side effects on the body.

Dual Encapsulation is a technology used in some SOLGAR probiotics, such as Advanced Multibillion Dophilus and Advanced Acidophilus Plus. The use of this technology makes it possible to preserve the viability of probiotic cultures (bifidobacteria and lactobacilli) when passing through the aggressive acidic environment of the stomach.