Side effects of calcium with vitamin d. Calcium and Vitamin D Combination: Benefits, Side Effects, and Usage Guide

12.09.202319.07.2023 by alexxlab

What are the main benefits of calcium and vitamin D combination supplements. How do these supplements promote bone health and prevent osteoporosis. What are the potential side effects and precautions to consider when taking calcium with vitamin D.

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Understanding Calcium and Vitamin D Combination Supplements

Calcium and vitamin D combination supplements are widely used to promote bone health and prevent conditions like osteoporosis. These supplements contain calcium, an essential mineral for bone formation, along with vitamin D, which aids in calcium absorption. Available over-the-counter under various brand names, these supplements play a crucial role in maintaining strong bones and overall skeletal health.

Key Components of Calcium and Vitamin D Supplements

Calcium: A vital mineral for bone structure and strength
Vitamin D: Enhances calcium absorption in the body
Additional ingredients: May vary by brand

Do calcium and vitamin D supplements really work? Research has shown that when taken as directed, these supplements can effectively increase bone density and reduce the risk of fractures, especially in older adults or those with calcium deficiencies.

Health Benefits of Calcium and Vitamin D Combination

The combination of calcium and vitamin D offers several health benefits, primarily focused on bone health and related conditions. Understanding these benefits can help individuals make informed decisions about incorporating these supplements into their daily routine.

Primary Benefits of Calcium and Vitamin D Supplements

Promotes bone health and strength
Helps prevent osteoporosis
Treats calcium deficiencies
Supports overall skeletal structure
May reduce the risk of fractures in older adults

Are there any additional benefits beyond bone health? While bone health is the primary focus, some studies suggest that calcium and vitamin D may also play a role in muscle function, nerve signaling, and maintaining a healthy immune system.

Potential Side Effects and Precautions

While calcium and vitamin D supplements are generally safe for most people, it’s essential to be aware of potential side effects and take necessary precautions. Understanding these factors can help users minimize risks and optimize the benefits of supplementation.

Common Side Effects

Nausea and vomiting
Constipation
Increased thirst or urination
Muscle weakness
Bone pain
Confusion or fatigue
Irregular heartbeat
Headache
Dry mouth or metallic taste

Can calcium and vitamin D supplements cause serious side effects? In rare cases, these supplements may lead to more severe complications, particularly if taken in excessive amounts or by individuals with certain health conditions. It’s crucial to consult a healthcare provider before starting any new supplement regimen.

Precautions and Contraindications

Certain individuals should exercise caution or avoid calcium and vitamin D supplements without medical supervision. These include people with:

Kidney disease or kidney stones
Heart disease
Cancer
High blood calcium levels
Circulation problems
Parathyroid gland disorders

Is it safe to take calcium and vitamin D supplements during pregnancy or while breastfeeding? Pregnant or nursing women should consult their healthcare provider before using these supplements, as their dosage needs may differ.

Proper Dosage and Administration

Adhering to the correct dosage and administration guidelines is crucial for maximizing the benefits of calcium and vitamin D supplements while minimizing potential risks. Users should follow the instructions provided on the product label or as directed by their healthcare provider.

General Dosage Guidelines

Follow the recommended daily intake on the product label
Do not exceed the prescribed dosage
Take supplements with food for better absorption
Space out doses throughout the day for optimal absorption

How often should calcium and vitamin D supplements be taken? The frequency of supplementation depends on the specific product and individual needs. Some formulations may require once-daily dosing, while others may be taken multiple times per day.

Missed Dose Protocol

If a dose is missed, take it as soon as remembered. However, if it’s close to the time for the next scheduled dose, skip the missed dose and resume the regular dosing schedule. Never double up on doses to make up for a missed one.

Drug Interactions and Considerations

Calcium and vitamin D supplements can interact with various medications and other supplements. Being aware of these interactions is essential for maintaining overall health and ensuring the effectiveness of both the supplements and other medications.

Potential Drug Interactions

Antibiotics (e.g., tetracyclines, quinolones)
Bisphosphonates (used for osteoporosis)
Thyroid medications
Diuretics
Antacids containing aluminum or magnesium
Certain heart medications

Should calcium and vitamin D supplements be taken with other medications? It’s advisable to space out the timing of these supplements and other medications. Consult a healthcare provider or pharmacist for specific guidance on managing potential interactions.

Dietary Considerations

Certain foods and beverages can affect the absorption and effectiveness of calcium and vitamin D supplements:

High-fiber foods may decrease calcium absorption
Excessive caffeine or alcohol intake can interfere with calcium absorption
Vitamin D absorption may be enhanced when taken with fatty foods

How can dietary choices impact the effectiveness of calcium and vitamin D supplements? Maintaining a balanced diet rich in calcium and vitamin D-containing foods can complement supplement intake and support overall bone health.

Special Populations and Considerations

While calcium and vitamin D supplements are beneficial for many individuals, certain populations may have specific needs or considerations when it comes to supplementation. Understanding these special circumstances can help ensure safe and effective use of these supplements.

Elderly Population

Older adults often have an increased need for calcium and vitamin D due to:

Reduced calcium absorption with age
Decreased skin synthesis of vitamin D
Higher risk of osteoporosis and fractures

Why is calcium and vitamin D supplementation particularly important for the elderly? As we age, the risk of bone loss and fractures increases, making adequate intake of these nutrients crucial for maintaining bone density and overall skeletal health.

Pregnant and Breastfeeding Women

Pregnant and breastfeeding women have increased calcium and vitamin D requirements to support fetal development and infant nutrition. However, dosage needs may differ, and consultation with a healthcare provider is essential.

Individuals with Malabsorption Disorders

People with conditions that affect nutrient absorption, such as celiac disease or inflammatory bowel disease, may require special consideration when it comes to calcium and vitamin D supplementation. Higher doses or alternative formulations may be necessary to ensure adequate intake.

Alternative Sources of Calcium and Vitamin D

While supplements are an effective way to increase calcium and vitamin D intake, it’s important to consider natural sources of these nutrients as well. A balanced diet rich in calcium and vitamin D can complement or, in some cases, replace the need for supplementation.

Dietary Sources of Calcium

Dairy products (milk, yogurt, cheese)
Leafy green vegetables (kale, spinach, collard greens)
Fish with edible bones (sardines, canned salmon)
Fortified foods (certain juices, cereals, and plant-based milk alternatives)
Nuts and seeds (almonds, sesame seeds)

Dietary Sources of Vitamin D

Fatty fish (salmon, mackerel, tuna)
Egg yolks
Mushrooms exposed to UV light
Fortified foods (milk, orange juice, cereals)

Can dietary sources provide sufficient calcium and vitamin D? For many individuals, a well-balanced diet can provide adequate amounts of these nutrients. However, those with specific health conditions, dietary restrictions, or increased needs may benefit from supplementation.

Sunlight Exposure for Vitamin D

The body can produce vitamin D when the skin is exposed to sunlight. However, factors such as geographical location, time of year, skin pigmentation, and use of sunscreen can affect vitamin D synthesis. Balancing sun exposure with skin cancer risk is important when considering this natural source of vitamin D.

Monitoring and Long-Term Use of Calcium and Vitamin D Supplements

Long-term use of calcium and vitamin D supplements requires careful monitoring to ensure safety and effectiveness. Regular check-ups and potential adjustments to the supplementation regimen may be necessary based on individual health status and changing needs.

Regular Health Assessments

Individuals taking calcium and vitamin D supplements long-term should consider:

Regular bone density scans to monitor bone health
Blood tests to check calcium and vitamin D levels
Kidney function tests, especially for those at risk of kidney stones
Cardiovascular health assessments

How often should individuals on long-term calcium and vitamin D supplementation have check-ups? The frequency of monitoring depends on individual health status and risk factors. Consult with a healthcare provider to determine an appropriate schedule for assessments.

Potential Long-Term Effects

While calcium and vitamin D supplements are generally safe, long-term use may be associated with certain risks:

Increased risk of kidney stones in susceptible individuals
Potential cardiovascular effects (research is ongoing and inconclusive)
Possible interactions with long-term medications

Is it necessary to take breaks from calcium and vitamin D supplementation? Some healthcare providers may recommend periodic breaks or cycling of supplement use to minimize potential risks associated with long-term use. However, this approach should be discussed with a healthcare professional based on individual needs and health status.

Adjusting Supplementation Over Time

As individuals age or experience changes in health status, their calcium and vitamin D needs may change. Regular consultations with healthcare providers can help ensure that supplementation remains appropriate and effective over time.

Factors that may necessitate adjustments in supplementation include:

Changes in dietary habits
Hormonal changes (e.g., menopause)
Development of new health conditions
Changes in medication regimens

How can individuals ensure their calcium and vitamin D supplementation remains appropriate over time? Regular communication with healthcare providers, staying informed about the latest research, and being attentive to any changes in health or medication use are key to maintaining an effective supplementation regimen.

Calcium and Vitamin D Combination (Calcium 500+D)

Brand Names:Calcarb with D, Calcet, Calcet Petites, Calcio Del Mar, Calcitrate with D, Calcium 500+D

By Julie Lynn MarksMedically Reviewed by Sanjai Sinha, MD

Reviewed: November 17, 2020

Calcium and vitamin D combination is a supplement that helps promote bone health, treat a calcium deficiency, and protect against osteoporosis.

Calcium is a natural mineral that plays a role in the body’s bone formation process. Vitamin D helps your body absorb calcium.

This supplement is sold under many different brands and is available as an over-the-counter (OTC) product.

uses

What is Calcium And Vitamin D Combination (Calcium 500+D) used for?

Osteoporosis
Dietary Supplement

warnings

What is the most important information I should know about Calcium And Vitamin D Combination (Calcium 500+D)?

Ask a doctor or pharmacist if this medicine is safe to use if you have:

kidney disease;
kidney stones;
heart disease;
cancer;
high levels of calcium in your blood;
circulation problems; or
a parathyroid gland disorder.

Ask a doctor before using this product if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing.

Side Effects

What are the side effects of Calcium And Vitamin D Combination (Calcium 500+D)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have signs of too much calcium in your body, such as:

nausea, vomiting, constipation;
increased thirst or urination;
muscle weakness, bone pain; or
confusion, lack of energy, or feeling tired.

Common side effects may include:

an irregular heartbeat;
weakness, drowsiness, headache;
dry mouth, or a metallic taste in your mouth; or
muscle or bone pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Calcium And Vitamin D Combination (Calcium 500+D) if I’m pregnant or breastfeeding?

Risk cannot be ruled out

Based on FDA pregnancy categories

Ask a doctor before using this product if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing.

Interactions

What drugs and food should I avoid while taking Calcium And Vitamin D Combination (Calcium 500+D)?

Ask a doctor or pharmacist before taking any multivitamins, mineral supplements, or antacids while you are taking calcium and vitamin D combination.

Dosage Guidelines & Tips

How to take Calcium And Vitamin D Combination (Calcium 500+D)?

Use Calcium And Vitamin D Combination (Calcium 500+D) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

What should I do if I missed a dose of Calcium And Vitamin D Combination (Calcium 500+D)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Overdose Signs

What happens if I overdose on Calcium And Vitamin D Combination (Calcium 500+D)?

If you think you or someone else may have overdosed on: Calcium And Vitamin D Combination (Calcium 500+D), call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn’t breathing after taking Calcium And Vitamin D Combination (Calcium 500+D), call 911

911

What to Expect

You may experience mild side effects, such as minor gas or constipation, when taking calcium and vitamin D combination. If this occurs, try increasing your fluid intake or switching to a different brand.

Secondary Uses

Calcium and vitamin D combination may be used for purposes that aren’t listed in this guide.

Images

CALCET, MPC

Color: yellow

Shape: rectangular

Form: film coated

Imprint: CALCET, MPC

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Medical Disclaimer

Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Cerner Multum™ provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. The information within all other sections is proprietary to Everyday Health.

Calcium and vitamin D combination Uses, Side Effects & Warnings

Generic name: calcium and vitamin D combination [ KAL-see-um-and-VYE-ta-min-D ]
Brand names: Calcitrate with D, Caltrate 600+D Soft Chews, Citracal + D, Os-Cal Extra D3, Oystercal-D,
… show all 50 brands
UpCal D, Os-Cal 250 with D, Oysco D, Dical-D, Calcet, Oyster Shell Calcium with Vitamin D, O-Cal-D, Oyster-D, Oyst-Cal-D, Caltro with Vitamin D, Oysco 500 with D, Oysco D with Calcium, Os-Cal with D, Calcarb with D, Posture-D H/P, Dical Captabs, Dicalphos plus D, Os-Cal 500 with D, Caltrate 600 with D Plus Soy, Caltrate Colon Health, Calvite P/D, Sedecal D, Chewable Calcium with Vitamin D, Osteocit D Plus, Os-Cal 500 + D, Citracal Petites, Citracal Creamy Bites, Citracal 250 mg + D, Calcio Del Mar, Citrus Calcium with Vitamin D, Calcium 600+D, Risacal-D, Liquid Calcium with Vitamin D, Citracal Maximum + D, Citracal Calcium + D Slow Release 1200, Citracal Calcium Gummies, Caltrate Gummy Bites, Super Calcium 600 + D3 400, Os-Cal Calcium+D3, Caltrate 600 + D, Citracal Regular, Calcet Petites, Calcium 500+D, D3 with Calcium, Calcium Plus Vitamin D3

Dosage forms: oral capsule (600 mg-5 mcg), oral powder for reconstitution (500 mg-12. 5 mcg/5 g), oral tablet ((as carbonate and lactate) 200 mg-6.25 mcg,
… show all 19 dosage forms
117 mg-3.325 mcg, 200 mg-6.25 mcg, 250 mg-3.125 mcg, 250 mg-5 mcg, 315 mg-5 mcg, 315 mg-6.25 mcg, 500 mg-10 mcg, 500 mg-15 mcg, 500 mg-3.125 mcg, 500 mg-5 mcg, 600 mg-10 mcg, 600 mg-20 mcg, 600 mg-3.125 mcg, 600 mg-5 mcg), oral tablet, chewable (250 mg-10 mcg; 250 mg-12.5 mcg; 500 mg-10 mcg; 500 mg-2.5 mcg; 600 mg-20 mcg), oral tablet, extended release (600 mg-12.5 mcg)

Drug class: Vitamin and mineral combinations

Medically reviewed by Drugs.com on May 22, 2023. Written by Cerner Multum.

What is calcium and vitamin D combination?

Calcium is a mineral that is necessary for many functions of the body, especially bone formation and maintenance. Vitamin D helps the body absorb calcium.

Calcium and vitamin D combination is used to treat or prevent a calcium deficiency.

There are many brands and forms of calcium and vitamin D combination available. Not all brands are listed on this leaflet.

Calcium and vitamin D combination may also be used for purposes not listed in this medication guide.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

Ask a doctor or pharmacist if calcium and vitamin D combination is safe to use if you have:

kidney disease;
kidney stones;
heart disease;
cancer;
high levels of calcium in your blood;
circulation problems; or
a parathyroid gland disorder.

Ask a doctor before using this product if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing.

How should I take calcium and vitamin D combination?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Check the label of your calcium and vitamin D combination product to see if it should be taken with or without food.

Take the regular tablet with a full glass of water.

The chewable tablet must be chewed before you swallow it.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

Calcium and vitamin D may be only part of a complete program of treatment that also includes dietary changes. Learn about the foods that contain calcium and vitamin D.

Your supplement dose may need to be adjusted as you make changes to your diet. Follow your doctor’s instructions very closely.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking calcium and vitamin D combination?

Ask a doctor or pharmacist before taking any multivitamins, mineral supplements, or antacids while you are taking calcium and vitamin D combination.

Calcium and vitamin D combination side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have signs of too much calcium in your body, such as:

nausea, vomiting, constipation;
increased thirst or urination;
muscle weakness, bone pain; or
confusion, lack of energy, or feeling tired.

Common side effects of calcium and vitamin D combination may include:

an irregular heartbeat;
weakness, drowsiness, headache;
dry mouth, or a metallic taste in your mouth; or
muscle or bone pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Calcium and vitamin D combination dosing information

Usual Adult Dose for Osteoporosis:

Calcium – General Range: 1000 mg to 1300 mg daily

Vitamin D – General Range: 200 international units to 800 international units daily

Note: While much larger vitamin D dosages have been recommended as a single agent, many calcium-vitamin D combination supplements will contain approximately 200 international units to 400 international units of vitamin D per dose.

Usual Adult Dose for Dietary Supplement:

Calcium – General Range: 1000 mg to 1300 mg daily

Vitamin D – General Range: 200 international units to 800 international units daily

What other drugs will affect calcium and vitamin D combination?

Calcium can make it harder for your body to absorb certain medicines, and some medicines can make it harder for your body to absorb vitamin D. If you take other medications, take them at least 2 hours before or 4 to 6 hours after you take calcium and vitamin D combination.

Other drugs may affect calcium and vitamin D combination, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

More about calcium / vitamin d

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Patient resources

Patient Information
Calcium and Vitamin D Chewable Tablets
Calcium and Vitamin D Liquid
Calcium and Vitamin D Powder

Other brands

Caltrate 600+D, Citracal + D, Oystercal-D, Os-Cal Calcium+D3, . .. +4 more

Related treatment guides

Dietary Supplementation
Osteoporosis

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Calcium-D3-MIC – instructions for use, doses, side effects, reviews of the drug: capsules, 166.7 mg + 66.7 IU

0.001 ‰

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All forms of release, dosages, registration certificates, drug manufacturers, drug characteristics

Calcium-D3-MIK (capsules, 166. 7 mg + 66.7 IU), instructions for medical use RU No. LSR-000019/09

Active substance
ATX
Nosological classification (ICD-10)
Pharmacological group
Dosage form
Compound
pharmachologic effect
Description of the dosage form
Pharmacokinetics
Indications
Contraindications
Use during pregnancy and lactation
Dosage and administration
Side effects
Interaction
Overdose
special instructions
Release form
Terms of dispensing from pharmacies
Storage conditions
Best before date
Order in Moscow pharmacies
Reviews

Active ingredient

Calcium carbonate + Colecalciferol (Calcium carbonate + Colecalciferol)

ATX

A12AX Calcium preparations in combination with vitamin D and/or other preparations

Nosological classification (ICD-10)

ICD-10 code list

Pharmacological group

Vitamins and vitamin-like products in combinations

Bone and cartilage metabolism correctors in combinations

Dosage form

Capsules.

Composition

1
capsule contains:

Active ingredients:

Calcium
carbonate – 416.3 mg (in terms of calcium – 166.7 mg),
colecalciferol type 100 CWS – 0.667 mg (in terms of
colecalciferol – 0.001667 mg (66.7 IU)).

Composition
cholecalciferol type 100 CWS: cholecalciferol crystalline, α‑tocopherol,
soybean oil, corn starch, hydrolyzed gelatin, sucrose.

Excipient:

Starch
potato.

Composition of the gelatin capsule shell:

Composition
hard gelatin capsule bodies: gelatin, purified water, titanium dioxide
E171; composition of the cap of a hard gelatin capsule: gelatin, purified water,
titanium dioxide E171, alluring red dye E129, dye
quinoline yellow E104.

Combined
drug, the action of which is due to its constituent components.
Regulates the exchange of calcium and phosphate ions, reduces resorption and increases
bone density, compensates for the lack of calcium ions and vitamin D ₃
in the body, enhances the absorption of calcium ions in the intestine and reabsorption
phosphate in the kidneys, promotes bone mineralization.

Calcium
carbonate is involved in the formation of bone tissue, blood clotting,
in maintaining stable cardiac activity, in the implementation of processes
transmission of nerve impulses. The use of calcium and vitamin D ₃
prevents an increase in the production of parathyroid hormone, which is
stimulator of increased bone resorption.

Description of dosage form

Capsules
hard, gelatinous No. 0 cylindrical shape with hemispherical ends
with white body and orange lid.

Content
capsules – powder of white or almost white color.

Pharmacokinetics

Vitamin D ₃
absorbed in the small intestine. Calcium is absorbed in ionized form
in the proximal small intestine through active
transport mechanism.

Readings

–
Prevention and
treatment and deficiency of calcium and/or vitamin D ₃ .

–
With insufficient
intake of calcium and vitamin D ₃ into the body against the background
malnutrition.

–
With increased
body needs for calcium and vitamin D ₃
during pregnancy and breastfeeding, as well as in children over 12
years during a period of intensive growth.

–
Prevention and
as part of the complex therapy of osteoporosis (menopausal, senile,
“steroid”, idiopathic, etc.).

Contraindications

–
Hypercalcemia
(increased concentration of calcium in the blood).

–
Hypercalciuria
(increased calcium in the urine).

–
Nephurolithiasis.

–
Hypervitaminosis
vitamin D ₃ .

–
Increased
sensitivity to the components of the drug.

–
severe renal
failure.

–
active form
tuberculosis.

–
Sarcoidosis.

–
Osteoporosis,
caused by immobilization.

–
Urolithiasis
disease.

–
Atherosclerosis.

–
Childhood
up to 12 years old.

With caution

Renal
insufficiency, benign granulomatosis, taking glycosides and thiazide
diuretics, pregnancy, lactation.

Use in pregnancy and lactation

Daily
the dose should not exceed 1500 mg calcium and 600 IU vitamin D ₃.
Hypercalcemia developing against the background of an overdose during pregnancy
can cause defects in the mental and physical development of the child.

Vitamin D ₃
and its metabolites can pass into breast milk, therefore, it is necessary to take into account
intake of calcium and vitamin D ₃ from other sources in the mother
and child. An overdose during pregnancy may lead to
mental and physical development of the child.

Dosage and administration

Information for healthcare professionals only.
Are you a healthcare professional?

Adults and children over 12:
2-3 capsules 2 times a day, morning and evening, mainly
while eating.

Side effects

Allergic
reactions, dysfunction of the gastrointestinal tract (constipation or diarrhea, flatulence,
nausea, abdominal pain), hypercalcemia and hypercalciuria (increased
calcium in blood or urine).