Side effects of calcium with vitamin d. Calcium and Vitamin D Combination: Benefits, Side Effects, and Usage Guide

12.09.202319.07.2023 by alexxlab

What are the benefits of calcium and vitamin D combination. How to use calcium and vitamin D supplements safely. What are the potential side effects of calcium and vitamin D combination. When should you consult a doctor before taking calcium and vitamin D supplements.

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Understanding Calcium and Vitamin D Combination Supplements

Calcium and vitamin D combination supplements are widely used to promote bone health, treat calcium deficiencies, and protect against osteoporosis. These supplements combine two essential nutrients that work synergistically in the body. Calcium is a vital mineral for bone formation, while vitamin D enhances calcium absorption, making it a crucial component in maintaining strong, healthy bones.

Available over-the-counter under various brand names, these supplements offer a convenient way to ensure adequate intake of both nutrients. However, it’s important to understand their proper use, potential benefits, and possible side effects.

How do calcium and vitamin D work together?

Calcium and vitamin D have a symbiotic relationship in the body. Calcium is the primary building block of bones and teeth, while vitamin D acts as a facilitator, enhancing the body’s ability to absorb calcium from the digestive tract. Without sufficient vitamin D, the body may struggle to utilize calcium effectively, potentially leading to weakened bones and increased risk of fractures.

Key Benefits of Calcium and Vitamin D Combination

The combination of calcium and vitamin D offers several important health benefits:

Promotes strong bone development and maintenance
Helps prevent and manage osteoporosis
Supports proper muscle function
May reduce the risk of certain cancers
Contributes to overall skeletal health

These supplements are particularly beneficial for individuals who may not get enough calcium and vitamin D through their diet alone, such as those with lactose intolerance, vegans, or older adults with reduced ability to absorb nutrients.

Can calcium and vitamin D supplements replace a balanced diet?

While supplements can be beneficial, they should not be viewed as a substitute for a balanced diet rich in calcium and vitamin D. Whole foods provide additional nutrients and compounds that work in concert with calcium and vitamin D to support overall health. It’s always best to aim for a well-rounded diet and use supplements as a complement when necessary.

Proper Usage and Dosage Guidelines

To maximize the benefits of calcium and vitamin D combination supplements, it’s crucial to follow proper usage guidelines:

Follow the recommended dosage on the product label or as prescribed by your healthcare provider.
Take the supplement with food to enhance absorption.
Space out doses throughout the day for optimal absorption if taking high doses.
Be consistent with your intake for best results.
Avoid taking more than the recommended amount, as excessive intake can lead to adverse effects.

How much calcium and vitamin D do adults need daily?

The recommended daily intake varies based on age, gender, and individual health factors. Generally, adults need between 1000-1200 mg of calcium and 600-800 IU of vitamin D daily. However, it’s best to consult with a healthcare provider to determine the optimal dosage for your specific needs.

Potential Side Effects and Precautions

While calcium and vitamin D supplements are generally safe for most people when taken as directed, they can cause side effects in some individuals. Common side effects may include:

Constipation
Bloating and gas
Nausea
Dry mouth
Headache

In rare cases, more serious side effects can occur, particularly if the supplements are taken in excessive amounts. These may include:

Kidney stones
Hypercalcemia (excessive calcium in the blood)
Irregular heartbeat
Confusion or disorientation

Who should exercise caution when taking calcium and vitamin D supplements?

Certain individuals should consult with a healthcare provider before taking calcium and vitamin D supplements, including those with:

Kidney disease or a history of kidney stones
Heart disease
Parathyroid disorders
High blood calcium levels
Certain types of cancer

Pregnant and breastfeeding women should also consult their healthcare provider, as their calcium and vitamin D needs may differ.

Interactions with Medications and Other Supplements

Calcium and vitamin D supplements can interact with various medications and other supplements. It’s important to be aware of potential interactions to avoid adverse effects or reduced efficacy of either the supplement or medication.

Which medications may interact with calcium and vitamin D supplements?

Some medications that may interact with calcium and vitamin D supplements include:

Certain antibiotics (e.g., tetracyclines, quinolones)
Bisphosphonates used to treat osteoporosis
Thyroid medications
Some blood pressure medications
Diuretics

To avoid potential interactions, it’s advisable to take calcium and vitamin D supplements at least 2 hours before or after taking other medications. Always inform your healthcare provider about all supplements and medications you’re taking.

Choosing the Right Calcium and Vitamin D Supplement

With numerous brands and formulations available, selecting the right calcium and vitamin D supplement can be overwhelming. Consider the following factors when choosing a supplement:

Calcium form: Calcium carbonate and calcium citrate are common forms, with calcium citrate being more easily absorbed.
Vitamin D type: Look for vitamin D3 (cholecalciferol), which is more effective than vitamin D2.
Additional ingredients: Some formulations include magnesium or other minerals that support bone health.
Dosage: Choose a supplement that helps you meet your daily requirements without exceeding them.
Third-party testing: Opt for brands that undergo third-party testing for quality and purity.

Is there a difference between natural and synthetic forms of calcium and vitamin D?

While both natural and synthetic forms can be effective, some studies suggest that natural forms may be more easily absorbed by the body. However, the difference is often minimal, and both types can contribute to meeting your nutritional needs. The most important factor is choosing a high-quality supplement and taking it consistently.

Lifestyle Factors That Affect Calcium and Vitamin D Absorption

While taking supplements is important, various lifestyle factors can impact how effectively your body absorbs and utilizes calcium and vitamin D:

Sun exposure: Sunlight helps your body produce vitamin D naturally.
Diet: Consuming foods rich in calcium and vitamin D enhances overall intake.
Exercise: Weight-bearing exercises can help improve bone density.
Alcohol consumption: Excessive alcohol intake can interfere with calcium absorption.
Smoking: Tobacco use can reduce calcium absorption and increase bone loss.

How can you naturally increase your calcium and vitamin D intake?

To boost your calcium and vitamin D levels naturally:

Include dairy products, leafy greens, and fortified foods in your diet.
Spend time outdoors to get natural vitamin D from sunlight (with proper sun protection).
Incorporate fatty fish like salmon and mackerel into your meals.
Choose calcium-fortified plant-based milk alternatives if you’re lactose intolerant.
Consume vitamin D-rich foods such as egg yolks and mushrooms.

By combining a balanced diet with appropriate supplementation and healthy lifestyle choices, you can optimize your calcium and vitamin D intake for better bone health and overall well-being.

Monitoring Your Calcium and Vitamin D Levels

Regular monitoring of your calcium and vitamin D levels is crucial to ensure you’re maintaining optimal health and avoiding potential complications from deficiency or excess. Your healthcare provider can perform blood tests to assess your levels and adjust your supplementation if necessary.

How often should calcium and vitamin D levels be checked?

The frequency of testing depends on individual factors such as age, health conditions, and risk factors. Generally, adults should have their vitamin D levels checked every 1-2 years, while calcium levels may be monitored as part of routine blood work. Those with specific health concerns or taking high doses of supplements may require more frequent monitoring.

Signs that may indicate a need for testing include:

Unexplained fatigue or weakness
Bone pain or frequent fractures
Muscle cramps or spasms
Changes in mood or cognitive function
Digestive issues such as constipation or abdominal pain

If you experience any of these symptoms, consult your healthcare provider for evaluation and potential testing.

Long-term Benefits and Considerations

While the immediate benefits of calcium and vitamin D supplementation are well-documented, it’s important to consider the long-term effects and potential benefits of consistent use:

Reduced risk of osteoporosis and fractures in older age
Potential protective effects against certain cancers and chronic diseases
Improved muscle strength and balance, reducing fall risk
Enhanced immune function
Possible reduction in the risk of cardiovascular disease

Can long-term use of calcium and vitamin D supplements have any negative effects?

While generally safe, long-term use of high-dose calcium supplements has been associated with an increased risk of kidney stones in some individuals. Additionally, excessive vitamin D intake over extended periods can lead to vitamin D toxicity, although this is rare. It’s crucial to follow recommended dosages and consult with a healthcare provider regularly to ensure safe and effective long-term use.

By maintaining a balanced approach to calcium and vitamin D supplementation, combined with a healthy lifestyle and regular medical check-ups, you can maximize the benefits while minimizing potential risks. Remember that individual needs may vary, and personalized advice from a healthcare professional is always the best guide for long-term supplement use.

Calcium and Vitamin D Combination (Calcium 500+D)

Brand Names:Calcarb with D, Calcet, Calcet Petites, Calcio Del Mar, Calcitrate with D, Calcium 500+D

By Julie Lynn MarksMedically Reviewed by Sanjai Sinha, MD

Reviewed: November 17, 2020

Calcium and vitamin D combination is a supplement that helps promote bone health, treat a calcium deficiency, and protect against osteoporosis.

Calcium is a natural mineral that plays a role in the body’s bone formation process. Vitamin D helps your body absorb calcium.

This supplement is sold under many different brands and is available as an over-the-counter (OTC) product.

uses

What is Calcium And Vitamin D Combination (Calcium 500+D) used for?

Osteoporosis
Dietary Supplement

warnings

What is the most important information I should know about Calcium And Vitamin D Combination (Calcium 500+D)?

Ask a doctor or pharmacist if this medicine is safe to use if you have:

kidney disease;
kidney stones;
heart disease;
cancer;
high levels of calcium in your blood;
circulation problems; or
a parathyroid gland disorder.

Ask a doctor before using this product if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing.

Side Effects

What are the side effects of Calcium And Vitamin D Combination (Calcium 500+D)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have signs of too much calcium in your body, such as:

nausea, vomiting, constipation;
increased thirst or urination;
muscle weakness, bone pain; or
confusion, lack of energy, or feeling tired.

Common side effects may include:

an irregular heartbeat;
weakness, drowsiness, headache;
dry mouth, or a metallic taste in your mouth; or
muscle or bone pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Calcium And Vitamin D Combination (Calcium 500+D) if I’m pregnant or breastfeeding?

Risk cannot be ruled out

Based on FDA pregnancy categories

Ask a doctor before using this product if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing.

Interactions

What drugs and food should I avoid while taking Calcium And Vitamin D Combination (Calcium 500+D)?

Ask a doctor or pharmacist before taking any multivitamins, mineral supplements, or antacids while you are taking calcium and vitamin D combination.

Dosage Guidelines & Tips

How to take Calcium And Vitamin D Combination (Calcium 500+D)?

Use Calcium And Vitamin D Combination (Calcium 500+D) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

What should I do if I missed a dose of Calcium And Vitamin D Combination (Calcium 500+D)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Overdose Signs

What happens if I overdose on Calcium And Vitamin D Combination (Calcium 500+D)?

If you think you or someone else may have overdosed on: Calcium And Vitamin D Combination (Calcium 500+D), call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn’t breathing after taking Calcium And Vitamin D Combination (Calcium 500+D), call 911

911

What to Expect

You may experience mild side effects, such as minor gas or constipation, when taking calcium and vitamin D combination. If this occurs, try increasing your fluid intake or switching to a different brand.

Secondary Uses

Calcium and vitamin D combination may be used for purposes that aren’t listed in this guide.

Images

CALCET, MPC

Color: yellow

Shape: rectangular

Form: film coated

Imprint: CALCET, MPC

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Medical Disclaimer

Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Cerner Multum™ provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. The information within all other sections is proprietary to Everyday Health.

Calcium and vitamin D combination Uses, Side Effects & Warnings

Generic name: calcium and vitamin D combination [ KAL-see-um-and-VYE-ta-min-D ]
Brand names: Calcitrate with D, Caltrate 600+D Soft Chews, Citracal + D, Os-Cal Extra D3, Oystercal-D,
… show all 50 brands
UpCal D, Os-Cal 250 with D, Oysco D, Dical-D, Calcet, Oyster Shell Calcium with Vitamin D, O-Cal-D, Oyster-D, Oyst-Cal-D, Caltro with Vitamin D, Oysco 500 with D, Oysco D with Calcium, Os-Cal with D, Calcarb with D, Posture-D H/P, Dical Captabs, Dicalphos plus D, Os-Cal 500 with D, Caltrate 600 with D Plus Soy, Caltrate Colon Health, Calvite P/D, Sedecal D, Chewable Calcium with Vitamin D, Osteocit D Plus, Os-Cal 500 + D, Citracal Petites, Citracal Creamy Bites, Citracal 250 mg + D, Calcio Del Mar, Citrus Calcium with Vitamin D, Calcium 600+D, Risacal-D, Liquid Calcium with Vitamin D, Citracal Maximum + D, Citracal Calcium + D Slow Release 1200, Citracal Calcium Gummies, Caltrate Gummy Bites, Super Calcium 600 + D3 400, Os-Cal Calcium+D3, Caltrate 600 + D, Citracal Regular, Calcet Petites, Calcium 500+D, D3 with Calcium, Calcium Plus Vitamin D3

Dosage forms: oral capsule (600 mg-5 mcg), oral powder for reconstitution (500 mg-12. 5 mcg/5 g), oral tablet ((as carbonate and lactate) 200 mg-6.25 mcg,
… show all 19 dosage forms
117 mg-3.325 mcg, 200 mg-6.25 mcg, 250 mg-3.125 mcg, 250 mg-5 mcg, 315 mg-5 mcg, 315 mg-6.25 mcg, 500 mg-10 mcg, 500 mg-15 mcg, 500 mg-3.125 mcg, 500 mg-5 mcg, 600 mg-10 mcg, 600 mg-20 mcg, 600 mg-3.125 mcg, 600 mg-5 mcg), oral tablet, chewable (250 mg-10 mcg; 250 mg-12.5 mcg; 500 mg-10 mcg; 500 mg-2.5 mcg; 600 mg-20 mcg), oral tablet, extended release (600 mg-12.5 mcg)

Drug class: Vitamin and mineral combinations

Medically reviewed by Drugs.com on May 22, 2023. Written by Cerner Multum.

What is calcium and vitamin D combination?

Calcium is a mineral that is necessary for many functions of the body, especially bone formation and maintenance. Vitamin D helps the body absorb calcium.

Calcium and vitamin D combination is used to treat or prevent a calcium deficiency.

There are many brands and forms of calcium and vitamin D combination available. Not all brands are listed on this leaflet.

Calcium and vitamin D combination may also be used for purposes not listed in this medication guide.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

Ask a doctor or pharmacist if calcium and vitamin D combination is safe to use if you have:

kidney disease;
kidney stones;
heart disease;
cancer;
high levels of calcium in your blood;
circulation problems; or
a parathyroid gland disorder.

Ask a doctor before using this product if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing.

How should I take calcium and vitamin D combination?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Check the label of your calcium and vitamin D combination product to see if it should be taken with or without food.

Take the regular tablet with a full glass of water.

The chewable tablet must be chewed before you swallow it.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

Calcium and vitamin D may be only part of a complete program of treatment that also includes dietary changes. Learn about the foods that contain calcium and vitamin D.

Your supplement dose may need to be adjusted as you make changes to your diet. Follow your doctor’s instructions very closely.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking calcium and vitamin D combination?

Ask a doctor or pharmacist before taking any multivitamins, mineral supplements, or antacids while you are taking calcium and vitamin D combination.

Calcium and vitamin D combination side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have signs of too much calcium in your body, such as:

nausea, vomiting, constipation;
increased thirst or urination;
muscle weakness, bone pain; or
confusion, lack of energy, or feeling tired.

Common side effects of calcium and vitamin D combination may include:

an irregular heartbeat;
weakness, drowsiness, headache;
dry mouth, or a metallic taste in your mouth; or
muscle or bone pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Calcium and vitamin D combination dosing information

Usual Adult Dose for Osteoporosis:

Calcium – General Range: 1000 mg to 1300 mg daily

Vitamin D – General Range: 200 international units to 800 international units daily

Note: While much larger vitamin D dosages have been recommended as a single agent, many calcium-vitamin D combination supplements will contain approximately 200 international units to 400 international units of vitamin D per dose.

Usual Adult Dose for Dietary Supplement:

Calcium – General Range: 1000 mg to 1300 mg daily

Vitamin D – General Range: 200 international units to 800 international units daily

What other drugs will affect calcium and vitamin D combination?

Calcium can make it harder for your body to absorb certain medicines, and some medicines can make it harder for your body to absorb vitamin D. If you take other medications, take them at least 2 hours before or 4 to 6 hours after you take calcium and vitamin D combination.

Other drugs may affect calcium and vitamin D combination, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

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Patient resources

Patient Information
Calcium and Vitamin D Chewable Tablets
Calcium and Vitamin D Liquid
Calcium and Vitamin D Powder

Other brands

Caltrate 600+D, Citracal + D, Oystercal-D, Os-Cal Calcium+D3, . .. +4 more

Related treatment guides

Dietary Supplementation
Osteoporosis

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Calcium-D3-MIC – instructions for use, doses, side effects, reviews of the drug: capsules, 166.7 mg + 66.7 IU

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All forms of release, dosages, registration certificates, drug manufacturers, drug characteristics

Calcium-D3-MIK (capsules, 166. 7 mg + 66.7 IU), instructions for medical use RU No. LSR-000019/09

Active substance
ATX
Nosological classification (ICD-10)
Pharmacological group
Dosage form
Compound
pharmachologic effect
Description of the dosage form
Pharmacokinetics
Indications
Contraindications
Use during pregnancy and lactation
Dosage and administration
Side effects
Interaction
Overdose
special instructions
Release form
Terms of dispensing from pharmacies
Storage conditions
Best before date
Order in Moscow pharmacies
Reviews

Active ingredient

Calcium carbonate + Colecalciferol (Calcium carbonate + Colecalciferol)

ATX

A12AX Calcium preparations in combination with vitamin D and/or other preparations

Nosological classification (ICD-10)

ICD-10 code list

Pharmacological group

Vitamins and vitamin-like products in combinations

Bone and cartilage metabolism correctors in combinations

Dosage form

Capsules.

Composition

1
capsule contains:

Active ingredients:

Calcium
carbonate – 416.3 mg (in terms of calcium – 166.7 mg),
colecalciferol type 100 CWS – 0.667 mg (in terms of
colecalciferol – 0.001667 mg (66.7 IU)).

Composition
cholecalciferol type 100 CWS: cholecalciferol crystalline, α‑tocopherol,
soybean oil, corn starch, hydrolyzed gelatin, sucrose.

Excipient:

Starch
potato.

Composition of the gelatin capsule shell:

Composition
hard gelatin capsule bodies: gelatin, purified water, titanium dioxide
E171; composition of the cap of a hard gelatin capsule: gelatin, purified water,
titanium dioxide E171, alluring red dye E129, dye
quinoline yellow E104.

Combined
drug, the action of which is due to its constituent components.
Regulates the exchange of calcium and phosphate ions, reduces resorption and increases
bone density, compensates for the lack of calcium ions and vitamin D ₃
in the body, enhances the absorption of calcium ions in the intestine and reabsorption
phosphate in the kidneys, promotes bone mineralization.

Calcium
carbonate is involved in the formation of bone tissue, blood clotting,
in maintaining stable cardiac activity, in the implementation of processes
transmission of nerve impulses. The use of calcium and vitamin D ₃
prevents an increase in the production of parathyroid hormone, which is
stimulator of increased bone resorption.

Description of dosage form

Capsules
hard, gelatinous No. 0 cylindrical shape with hemispherical ends
with white body and orange lid.

Content
capsules – powder of white or almost white color.

Pharmacokinetics

Vitamin D ₃
absorbed in the small intestine. Calcium is absorbed in ionized form
in the proximal small intestine through active
transport mechanism.

Readings

–
Prevention and
treatment and deficiency of calcium and/or vitamin D ₃ .

–
With insufficient
intake of calcium and vitamin D ₃ into the body against the background
malnutrition.

–
With increased
body needs for calcium and vitamin D ₃
during pregnancy and breastfeeding, as well as in children over 12
years during a period of intensive growth.

–
Prevention and
as part of the complex therapy of osteoporosis (menopausal, senile,
“steroid”, idiopathic, etc.).

Contraindications

–
Hypercalcemia
(increased concentration of calcium in the blood).

–
Hypercalciuria
(increased calcium in the urine).

–
Nephurolithiasis.

–
Hypervitaminosis
vitamin D ₃ .

–
Increased
sensitivity to the components of the drug.

–
severe renal
failure.

–
active form
tuberculosis.

–
Sarcoidosis.

–
Osteoporosis,
caused by immobilization.

–
Urolithiasis
disease.

–
Atherosclerosis.

–
Childhood
up to 12 years old.

With caution

Renal
insufficiency, benign granulomatosis, taking glycosides and thiazide
diuretics, pregnancy, lactation.

Use in pregnancy and lactation

Daily
the dose should not exceed 1500 mg calcium and 600 IU vitamin D ₃.
Hypercalcemia developing against the background of an overdose during pregnancy
can cause defects in the mental and physical development of the child.

Vitamin D ₃
and its metabolites can pass into breast milk, therefore, it is necessary to take into account
intake of calcium and vitamin D ₃ from other sources in the mother
and child. An overdose during pregnancy may lead to
mental and physical development of the child.

Dosage and administration

Information for healthcare professionals only.
Are you a healthcare professional?

Adults and children over 12:
2-3 capsules 2 times a day, morning and evening, mainly
while eating.

Side effects

Allergic
reactions, dysfunction of the gastrointestinal tract (constipation or diarrhea, flatulence,
nausea, abdominal pain), hypercalcemia and hypercalciuria (increased
calcium in blood or urine).