Side effects of calcium with vitamin d. Calcium and Vitamin D Combination: Benefits, Side Effects, and Usage Guide

11.09.202319.07.2023 by alexxlab

What are the main benefits of calcium and vitamin D combination supplements. How do these supplements promote bone health and prevent osteoporosis. What are the potential side effects and precautions to consider when taking calcium and vitamin D supplements.

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Understanding Calcium and Vitamin D Combination Supplements

Calcium and vitamin D combination supplements are widely used to support bone health and prevent conditions like osteoporosis. These supplements combine two essential nutrients that work synergistically in the body. Calcium is a vital mineral for bone formation and strength, while vitamin D aids in calcium absorption and utilization.

Many brands offer calcium and vitamin D combination products, such as Calcarb with D, Calcet, Calcitrate with D, and Calcium 500+D. These over-the-counter supplements provide a convenient way to ensure adequate intake of both nutrients.

The Role of Calcium and Vitamin D in Bone Health

Calcium plays a crucial role in maintaining strong bones and teeth. It is the most abundant mineral in the human body, with about 99% stored in bones and teeth. Vitamin D, often called the “sunshine vitamin,” is essential for calcium absorption in the intestines and helps regulate calcium levels in the blood.

Together, calcium and vitamin D work to:

Promote bone formation and mineralization
Maintain bone density and strength
Reduce the risk of osteoporosis and fractures
Support proper muscle function and nerve signaling

Key Benefits of Calcium and Vitamin D Supplements

Calcium and vitamin D combination supplements offer several important benefits:

1. Osteoporosis Prevention and Management

These supplements are commonly used to prevent and manage osteoporosis, a condition characterized by weakened bones and increased fracture risk. Adequate calcium and vitamin D intake can help maintain bone density and reduce the likelihood of fractures, especially in older adults.

2. Correction of Calcium Deficiency

For individuals with low calcium levels, these supplements can help restore proper calcium balance in the body. This is particularly important for those with dietary restrictions or absorption issues.

3. Support for Overall Bone Health

Even in the absence of osteoporosis or deficiency, calcium and vitamin D supplements can support overall bone health throughout life, helping to maintain strong and healthy bones.

4. Enhanced Calcium Absorption

The inclusion of vitamin D in these supplements ensures better calcium absorption in the intestines, maximizing the benefits of calcium intake.

Potential Side Effects and Precautions

While calcium and vitamin D supplements are generally safe, they can cause side effects in some individuals. Common side effects may include:

Constipation or gas
Nausea or stomach discomfort
Dry mouth or metallic taste
Headache or drowsiness

In rare cases, more serious side effects can occur, such as:

Signs of allergic reaction (hives, difficulty breathing, swelling)
Symptoms of hypercalcemia (excessive calcium in the blood)
Irregular heartbeat
Confusion or lack of energy

It’s important to consult a healthcare provider before starting these supplements, especially if you have pre-existing conditions like kidney disease, heart disease, or parathyroid disorders.

Proper Usage and Dosage Guidelines

To ensure safe and effective use of calcium and vitamin D supplements:

Follow the recommended dosage on the product label or as prescribed by your healthcare provider.
Take the supplement with food to enhance absorption and reduce the risk of side effects.
Spread out doses throughout the day if taking high amounts of calcium.
Stay hydrated to help prevent constipation.
Avoid taking the supplement with other medications unless approved by your doctor.

If you miss a dose, take it as soon as you remember, but skip the missed dose if it’s close to your next scheduled dose. Never double up on doses.

Interactions with Other Medications and Supplements

Calcium and vitamin D supplements can interact with various medications and other supplements. It’s crucial to inform your healthcare provider about all the medications and supplements you’re taking. Some potential interactions include:

Certain antibiotics (e.g., tetracyclines, quinolones)
Bisphosphonates used for osteoporosis
Thyroid medications
Iron supplements
Diuretics

To minimize interactions, it’s often recommended to take calcium and vitamin D supplements at least 2 hours apart from other medications.

Special Considerations for Pregnant and Breastfeeding Women

Pregnant and breastfeeding women often have increased calcium and vitamin D needs. However, it’s essential to consult with a healthcare provider before taking these supplements during pregnancy or while nursing. Dosage requirements may differ, and certain forms of the supplements may be more appropriate.

Adequate calcium and vitamin D intake during pregnancy and breastfeeding can support:

Fetal bone development
Maternal bone health
Proper calcium levels in breast milk

Healthcare providers can offer personalized recommendations based on individual needs and health status.

Choosing the Right Calcium and Vitamin D Supplement

When selecting a calcium and vitamin D supplement, consider the following factors:

1. Calcium Form

Different forms of calcium have varying absorption rates. Calcium carbonate is often the most economical and contains the highest percentage of elemental calcium. Calcium citrate may be better absorbed, especially in people with low stomach acid.

2. Vitamin D Type

Vitamin D3 (cholecalciferol) is generally preferred over vitamin D2 (ergocalciferol) due to its better absorption and effectiveness in raising blood levels of vitamin D.

3. Dosage

Look for supplements that provide an appropriate balance of calcium and vitamin D based on your individual needs and dietary intake.

4. Additional Ingredients

Some supplements may include other minerals or vitamins that support bone health, such as magnesium or vitamin K.

5. Brand Reputation

Choose reputable brands that undergo third-party testing for quality and purity.

It’s advisable to discuss your options with a healthcare provider or registered dietitian to determine the most suitable supplement for your needs.

Complementary Strategies for Bone Health

While calcium and vitamin D supplements can be beneficial, they should be part of a comprehensive approach to bone health. Other strategies to consider include:

1. Balanced Diet

Consume a variety of calcium-rich foods such as dairy products, leafy greens, and fortified foods. Also, include sources of vitamin D like fatty fish, egg yolks, and fortified foods.

2. Regular Exercise

Engage in weight-bearing and resistance exercises to strengthen bones and improve balance, reducing the risk of falls and fractures.

3. Sunlight Exposure

Spend time outdoors to allow your body to produce vitamin D naturally, but be mindful of sun protection.

4. Avoid Smoking and Excessive Alcohol

Both habits can negatively impact bone health and increase the risk of osteoporosis.

5. Regular Check-ups

Schedule regular bone density scans and check-ups with your healthcare provider to monitor your bone health and adjust your prevention or treatment plan as needed.

By combining these strategies with appropriate supplementation, you can significantly improve your overall bone health and reduce the risk of osteoporosis and related complications.

Calcium and Vitamin D Combination (Calcium 500+D)

Brand Names:Calcarb with D, Calcet, Calcet Petites, Calcio Del Mar, Calcitrate with D, Calcium 500+D

By Julie Lynn MarksMedically Reviewed by Sanjai Sinha, MD

Reviewed: November 17, 2020

Calcium and vitamin D combination is a supplement that helps promote bone health, treat a calcium deficiency, and protect against osteoporosis.

Calcium is a natural mineral that plays a role in the body’s bone formation process. Vitamin D helps your body absorb calcium.

This supplement is sold under many different brands and is available as an over-the-counter (OTC) product.

uses

What is Calcium And Vitamin D Combination (Calcium 500+D) used for?

Osteoporosis
Dietary Supplement

warnings

What is the most important information I should know about Calcium And Vitamin D Combination (Calcium 500+D)?

Ask a doctor or pharmacist if this medicine is safe to use if you have:

kidney disease;
kidney stones;
heart disease;
cancer;
high levels of calcium in your blood;
circulation problems; or
a parathyroid gland disorder.

Ask a doctor before using this product if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing.

Side Effects

What are the side effects of Calcium And Vitamin D Combination (Calcium 500+D)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have signs of too much calcium in your body, such as:

nausea, vomiting, constipation;
increased thirst or urination;
muscle weakness, bone pain; or
confusion, lack of energy, or feeling tired.

Common side effects may include:

an irregular heartbeat;
weakness, drowsiness, headache;
dry mouth, or a metallic taste in your mouth; or
muscle or bone pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pregnancy & Breastfeeding

Can I take Calcium And Vitamin D Combination (Calcium 500+D) if I’m pregnant or breastfeeding?

Risk cannot be ruled out

Based on FDA pregnancy categories

Ask a doctor before using this product if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing.

Interactions

What drugs and food should I avoid while taking Calcium And Vitamin D Combination (Calcium 500+D)?

Ask a doctor or pharmacist before taking any multivitamins, mineral supplements, or antacids while you are taking calcium and vitamin D combination.

Dosage Guidelines & Tips

How to take Calcium And Vitamin D Combination (Calcium 500+D)?

Use Calcium And Vitamin D Combination (Calcium 500+D) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

What should I do if I missed a dose of Calcium And Vitamin D Combination (Calcium 500+D)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Overdose Signs

What happens if I overdose on Calcium And Vitamin D Combination (Calcium 500+D)?

If you think you or someone else may have overdosed on: Calcium And Vitamin D Combination (Calcium 500+D), call your doctor or the Poison Control center

(800) 222-1222

If someone collapses or isn’t breathing after taking Calcium And Vitamin D Combination (Calcium 500+D), call 911

911

What to Expect

You may experience mild side effects, such as minor gas or constipation, when taking calcium and vitamin D combination. If this occurs, try increasing your fluid intake or switching to a different brand.

Secondary Uses

Calcium and vitamin D combination may be used for purposes that aren’t listed in this guide.

Images

CALCET, MPC

Color: yellow

Shape: rectangular

Form: film coated

Imprint: CALCET, MPC

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Medical Disclaimer

Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Cerner Multum™ provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. The information within all other sections is proprietary to Everyday Health.

Calcium and vitamin D combination Uses, Side Effects & Warnings

Generic name: calcium and vitamin D combination [ KAL-see-um-and-VYE-ta-min-D ]
Brand names: Calcitrate with D, Caltrate 600+D Soft Chews, Citracal + D, Os-Cal Extra D3, Oystercal-D,
… show all 50 brands
UpCal D, Os-Cal 250 with D, Oysco D, Dical-D, Calcet, Oyster Shell Calcium with Vitamin D, O-Cal-D, Oyster-D, Oyst-Cal-D, Caltro with Vitamin D, Oysco 500 with D, Oysco D with Calcium, Os-Cal with D, Calcarb with D, Posture-D H/P, Dical Captabs, Dicalphos plus D, Os-Cal 500 with D, Caltrate 600 with D Plus Soy, Caltrate Colon Health, Calvite P/D, Sedecal D, Chewable Calcium with Vitamin D, Osteocit D Plus, Os-Cal 500 + D, Citracal Petites, Citracal Creamy Bites, Citracal 250 mg + D, Calcio Del Mar, Citrus Calcium with Vitamin D, Calcium 600+D, Risacal-D, Liquid Calcium with Vitamin D, Citracal Maximum + D, Citracal Calcium + D Slow Release 1200, Citracal Calcium Gummies, Caltrate Gummy Bites, Super Calcium 600 + D3 400, Os-Cal Calcium+D3, Caltrate 600 + D, Citracal Regular, Calcet Petites, Calcium 500+D, D3 with Calcium, Calcium Plus Vitamin D3

Dosage forms: oral capsule (600 mg-5 mcg), oral powder for reconstitution (500 mg-12. 5 mcg/5 g), oral tablet ((as carbonate and lactate) 200 mg-6.25 mcg,
… show all 19 dosage forms
117 mg-3.325 mcg, 200 mg-6.25 mcg, 250 mg-3.125 mcg, 250 mg-5 mcg, 315 mg-5 mcg, 315 mg-6.25 mcg, 500 mg-10 mcg, 500 mg-15 mcg, 500 mg-3.125 mcg, 500 mg-5 mcg, 600 mg-10 mcg, 600 mg-20 mcg, 600 mg-3.125 mcg, 600 mg-5 mcg), oral tablet, chewable (250 mg-10 mcg; 250 mg-12.5 mcg; 500 mg-10 mcg; 500 mg-2.5 mcg; 600 mg-20 mcg), oral tablet, extended release (600 mg-12.5 mcg)

Drug class: Vitamin and mineral combinations

Medically reviewed by Drugs.com on May 22, 2023. Written by Cerner Multum.

What is calcium and vitamin D combination?

Calcium is a mineral that is necessary for many functions of the body, especially bone formation and maintenance. Vitamin D helps the body absorb calcium.

Calcium and vitamin D combination is used to treat or prevent a calcium deficiency.

There are many brands and forms of calcium and vitamin D combination available. Not all brands are listed on this leaflet.

Calcium and vitamin D combination may also be used for purposes not listed in this medication guide.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

Ask a doctor or pharmacist if calcium and vitamin D combination is safe to use if you have:

kidney disease;
kidney stones;
heart disease;
cancer;
high levels of calcium in your blood;
circulation problems; or
a parathyroid gland disorder.

Ask a doctor before using this product if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing.

How should I take calcium and vitamin D combination?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Check the label of your calcium and vitamin D combination product to see if it should be taken with or without food.

Take the regular tablet with a full glass of water.

The chewable tablet must be chewed before you swallow it.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

Calcium and vitamin D may be only part of a complete program of treatment that also includes dietary changes. Learn about the foods that contain calcium and vitamin D.

Your supplement dose may need to be adjusted as you make changes to your diet. Follow your doctor’s instructions very closely.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking calcium and vitamin D combination?

Ask a doctor or pharmacist before taking any multivitamins, mineral supplements, or antacids while you are taking calcium and vitamin D combination.

Calcium and vitamin D combination side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have signs of too much calcium in your body, such as:

nausea, vomiting, constipation;
increased thirst or urination;
muscle weakness, bone pain; or
confusion, lack of energy, or feeling tired.

Common side effects of calcium and vitamin D combination may include:

an irregular heartbeat;
weakness, drowsiness, headache;
dry mouth, or a metallic taste in your mouth; or
muscle or bone pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Calcium and vitamin D combination dosing information

Usual Adult Dose for Osteoporosis:

Calcium – General Range: 1000 mg to 1300 mg daily

Vitamin D – General Range: 200 international units to 800 international units daily

Note: While much larger vitamin D dosages have been recommended as a single agent, many calcium-vitamin D combination supplements will contain approximately 200 international units to 400 international units of vitamin D per dose.

Usual Adult Dose for Dietary Supplement:

Calcium – General Range: 1000 mg to 1300 mg daily

Vitamin D – General Range: 200 international units to 800 international units daily

What other drugs will affect calcium and vitamin D combination?

Calcium can make it harder for your body to absorb certain medicines, and some medicines can make it harder for your body to absorb vitamin D. If you take other medications, take them at least 2 hours before or 4 to 6 hours after you take calcium and vitamin D combination.

Other drugs may affect calcium and vitamin D combination, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

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Patient resources

Patient Information
Calcium and Vitamin D Chewable Tablets
Calcium and Vitamin D Liquid
Calcium and Vitamin D Powder

Other brands

Caltrate 600+D, Citracal + D, Oystercal-D, Os-Cal Calcium+D3, . .. +4 more

Related treatment guides

Dietary Supplementation
Osteoporosis

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Calcium-D3-MIC – instructions for use, doses, side effects, reviews of the drug: capsules, 166.7 mg + 66.7 IU

0.001 ‰

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All forms of release, dosages, registration certificates, drug manufacturers, drug characteristics

Calcium-D3-MIK (capsules, 166. 7 mg + 66.7 IU), instructions for medical use RU No. LSR-000019/09

Active substance
ATX
Nosological classification (ICD-10)
Pharmacological group
Dosage form
Compound
pharmachologic effect
Description of the dosage form
Pharmacokinetics
Indications
Contraindications
Use during pregnancy and lactation
Dosage and administration
Side effects
Interaction
Overdose
special instructions
Release form
Terms of dispensing from pharmacies
Storage conditions
Best before date
Order in Moscow pharmacies
Reviews

Active ingredient

Calcium carbonate + Colecalciferol (Calcium carbonate + Colecalciferol)

ATX

A12AX Calcium preparations in combination with vitamin D and/or other preparations

Nosological classification (ICD-10)

ICD-10 code list

Pharmacological group

Vitamins and vitamin-like products in combinations

Bone and cartilage metabolism correctors in combinations

Dosage form

Capsules.

Composition

1
capsule contains:

Active ingredients:

Calcium
carbonate – 416.3 mg (in terms of calcium – 166.7 mg),
colecalciferol type 100 CWS – 0.667 mg (in terms of
colecalciferol – 0.001667 mg (66.7 IU)).

Composition
cholecalciferol type 100 CWS: cholecalciferol crystalline, α‑tocopherol,
soybean oil, corn starch, hydrolyzed gelatin, sucrose.

Excipient:

Starch
potato.

Composition of the gelatin capsule shell:

Composition
hard gelatin capsule bodies: gelatin, purified water, titanium dioxide
E171; composition of the cap of a hard gelatin capsule: gelatin, purified water,
titanium dioxide E171, alluring red dye E129, dye
quinoline yellow E104.

Combined
drug, the action of which is due to its constituent components.
Regulates the exchange of calcium and phosphate ions, reduces resorption and increases
bone density, compensates for the lack of calcium ions and vitamin D ₃
in the body, enhances the absorption of calcium ions in the intestine and reabsorption
phosphate in the kidneys, promotes bone mineralization.

Calcium
carbonate is involved in the formation of bone tissue, blood clotting,
in maintaining stable cardiac activity, in the implementation of processes
transmission of nerve impulses. The use of calcium and vitamin D ₃
prevents an increase in the production of parathyroid hormone, which is
stimulator of increased bone resorption.

Description of dosage form

Capsules
hard, gelatinous No. 0 cylindrical shape with hemispherical ends
with white body and orange lid.

Content
capsules – powder of white or almost white color.

Pharmacokinetics

Vitamin D ₃
absorbed in the small intestine. Calcium is absorbed in ionized form
in the proximal small intestine through active
transport mechanism.

Readings

–
Prevention and
treatment and deficiency of calcium and/or vitamin D ₃ .

–
With insufficient
intake of calcium and vitamin D ₃ into the body against the background
malnutrition.

–
With increased
body needs for calcium and vitamin D ₃
during pregnancy and breastfeeding, as well as in children over 12
years during a period of intensive growth.

–
Prevention and
as part of the complex therapy of osteoporosis (menopausal, senile,
“steroid”, idiopathic, etc.).

Contraindications

–
Hypercalcemia
(increased concentration of calcium in the blood).

–
Hypercalciuria
(increased calcium in the urine).

–
Nephurolithiasis.

–
Hypervitaminosis
vitamin D ₃ .

–
Increased
sensitivity to the components of the drug.

–
severe renal
failure.

–
active form
tuberculosis.

–
Sarcoidosis.

–
Osteoporosis,
caused by immobilization.

–
Urolithiasis
disease.

–
Atherosclerosis.

–
Childhood
up to 12 years old.

With caution

Renal
insufficiency, benign granulomatosis, taking glycosides and thiazide
diuretics, pregnancy, lactation.

Use in pregnancy and lactation

Daily
the dose should not exceed 1500 mg calcium and 600 IU vitamin D ₃.
Hypercalcemia developing against the background of an overdose during pregnancy
can cause defects in the mental and physical development of the child.

Vitamin D ₃
and its metabolites can pass into breast milk, therefore, it is necessary to take into account
intake of calcium and vitamin D ₃ from other sources in the mother
and child. An overdose during pregnancy may lead to
mental and physical development of the child.

Dosage and administration

Information for healthcare professionals only.
Are you a healthcare professional?

Adults and children over 12:
2-3 capsules 2 times a day, morning and evening, mainly
while eating.

Side effects

Allergic
reactions, dysfunction of the gastrointestinal tract (constipation or diarrhea, flatulence,
nausea, abdominal pain), hypercalcemia and hypercalciuria (increased
calcium in blood or urine).