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Side effects of carditone: Prospective Safety Evaluation of a Cardiovascular Health Dietary Supplement in Adults with Prehypertension and Stage I Hypertension

Ayush Carditone & Balancing Your Blood Pressure
– Healthy Habits Living

Blood pressure, both high and low, can cause problems for other parts of your body. So what can you do to help prevent either of these extreme conditions?

There are many daily habits, diet choices, and other activities you can do to help minimize your risk of developing these conditions and to help control them if you already have them. Another strategy for regulating your blood pressure is to take Carditone, produced by Ayush Herbs. 

Ayush Carditone

By using a blend of herbs, Carditone strengthens both heart function and regulates blood pressure. Several of the herbs also promote balanced stress hormone levels.

Convolvulus pluricaulis is the main herb in Carditone. The common name for convolvulus pluricaulis is Shankhapushpi. It has a long history in traditional Ayurvedic medicine. The herb looks a lot like morning glory with its trailing vine and brilliant purple flowers. Traditionally it has been used for thousands of years for memory support, anxiety, depression, and sedation.

In lower doses, it helps to lower blood pressure by acting on the nervous system. Convolvulus pluricaulis regulates your body’s production of the stress hormones adrenaline and cortisol. An excess of these hormones is involved with high blood pressure.

Rauwolfia serpentina has a long history of research and use in lowering elevated blood pressure. The root of rauwolfia serpentina is used in herbal remedies. As with many other medicinal herbs, eastern cultures used this particular herb for centuries before modern and western medicine picked up the remedy. Interestingly, however, serpentina is not used for the same things that eastern cultures have historically utilized it. In Ayurvedic medicine, rauwolfia serpentina is also known as sarpagandha and chandrika. It is an evergreen shrub that is native to tropical regions all over the world from Europe to Australia. It has been used in India for insect bites, malaria, digestive problems, and as a cure for insanity.

As early as the 1940s, doctors were using and studying rauwolfia serpentina for high blood pressure. From 1939 to 1949 Dr. Rustom Jal Vakil collected data on his patients who were using rauwolfia serpentina to treat high blood pressure.  The results were remarkable and caused eastern physicians to adopt rauwolfia serpentina as the primary treatment for hypertension (high blood pressure).

More recently rauwolfia serpentina has been studied for the treatment of brain and mental disorders including bipolar, depression, and anxiety. It is used at lower doses for managing high blood pressure and in higher doses for mental and brain disorders.

How Do You Know If You Have High Blood Pressure?

Perhaps you have been told you have high blood pressure. We’ve all heard of high blood pressure, but what exactly is the pressure range that is considered normal? There are actually five different categories of blood pressure ranges, as the American Heart Association tells us, and those are Normal, Elevated, Hypertension Stages 1 and 2, and finally, Hypertensive Crisis. The maximum you want your heart range to be is in the “Normal”, at less than 120/80mm Hg. The “Elevated” range of 120-129/80 mm Hg, is usually cause for a trip to the doctor or an examination of your stress levels. Any range greater than 130/81 mm Hg has long term implications and is a reason for lifestyle and diet changes.

Over your lifespan, the greater your blood pressure or the more extreme your blood pressure range is, the more wear and tear your heart will endure, and the shorter amount of time your heart will beat.

So why do we have two different numbers when we’re talking about blood pressure?

The first number, in this case, 120 from the Normal blood pressure range refers to your Systolic blood pressure, which indicates how much pressure your blood is exerting against your artery walls as your heartbeats. The second number, for Normal range, 80, is your Diastolic blood pressure, which indicates how much pressure your blood is exerting against your artery walls while the heart is resting between beats.

Systolic and diastolic blood pressure measurements are different than pulse or heart rate values.

Now, why do we refer to the pressure as mm Hg, do you ask? The mm Hg is actually an abbreviation for millimeters of mercury, which is a heavy metal that was used in thermometers and pressure gauges. To keep everything consistent, modern medicine has kept this measuring system to avoid confusion.

Are there any side effects when taking Ayush Carditone?

Before you commit to taking a blood pressure medicine you may want to consider the possible side effects of these medications. Common side effects include diarrhea, dizziness, erection problems, fatigue, headaches, anxiety, and kidney disease. Ayush Carditone carries none of those side effects. You may also benefit from looking at your diet and lifestyle as a source of your hypertension.

A high sugar, high carbohydrate diet contributes to high blood pressure, high blood sugar, and high triglycerides. This trifecta of “highs” is referred to as metabolic syndrome. Risk factors for metabolic syndrome include obesity, sedentary lifestyle, sitting more than 7 hours per day, alcohol, smoking, and stress.

In our modern, fast-paced world, we often live on adrenaline and cortisol surges. We let the mental and emotional stress in our lives cause physical issues such as high blood pressure, insulin resistance, metabolic syndrome, and other serious diseases. Controlling blood pressure isn’t as easy as popping a pill. It needs to be a diet and lifestyle change. A low carbohydrate diet coupled with Ayush Carditone is a great and proven starting point.

If you would like expert guidance to manage your blood pressure please schedule a consult with Carly Neubert BA, NC.

 

Carly Neubert BA, NC

For additional recipes, biohacking tips and lifestyle hacks — check out my other blog on my coaching site www.cleancoachcarly.com! I post weekly about nutrition and lifestyle topics, all backed by science. Happy Reading!

 

Resources & References:

  • https://www.healthyhabitsliving.com/products/carditone-60-caplets
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566472/
  • https://www.heart.org/en/health-topics/high-blood-pressure/understanding-blood-pressure-readings
  • https://www.mayoclinic.org/diseases-conditions/high-blood-pressure/in-depth/high-blood-pressure-medication/art-20046280

Ingredients, Side Effects & More

A healthy heart is an essential component to overall physical health. The heart even has an emotional component–we say someone “didn’t have the heart for something” or “did it with their whole heart”. It is a vital organ and so it’s vital that we keep our hearts as healthy as possible with diet, exercise, and perhaps even a supplement or two.

With its ties to the ancient practice of Ayurveda, Ayush Herbs Carditone is a product designed to help your heart function at peak performance.

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Caditone’s Main Ingredient–Convolvulus Pluricaulis

Convolvulus pluricaulis is derived from the plant of the same name and is also known by its Ayurvedic name shankhapushpi. It has been used in India for centuries as a nerve tonic but there have been recent studies that have shown its potential as a powerful antioxidant.

C. pluricaulis works by breaking down free radicals and minimizing their detrimental effects on the tissues of the body. A high concentration of free radicals is thought to play a role in diseases as varied as Huntington’s disease, Alzheimer’s, and hypertension.

An in-depth study on the antioxidant potential and effects of C. pluricaulis found that its scavenging of free radicals is thought to have a neuroprotective effect in the brain, protecting neurons from damage. It is particularly useful when used during stress, preventing stress related memory loss. The researchers concluded that C. pluricaulis exhibits “rich antioxidant status” and “diminishes neuronal damage…by decreasing oxidative stress”. (1)

Carditone’s Supporting Ingredients

Rauwolfia was widely used to lower blood pressure until the 60’s, when a study came out erroneously linking it to depression. Although the study was found faulty, in both its methodology and conclusion, and current reviews of available literature indicate there is no link, if you have a tendency towards depression it might be better to skip any supplement containing this ingredient.

Carditone contains 50 mg of Rauwolfia, an amount found by reviews to have cardiovascular benefits without some of the side effects that can be found with doses above 100 mg. Commonly cited side effects of 100 mg and above tend to be gastrointestinal. (2)

Terminalia Arjuna has well documented antioxidant properties and is specifically used for heart conditions. A review of clinical studies found the effectiveness of T. Arjuna as an agent of lowering LDL cholesterol and lipid levels has been “sufficiently demonstrated”. Out of the studies they reviewed, a few were particularly interesting.

One study, regarding heart failure, found that treatment with T. Arjuna in patients with congestive heart failure “caused long lasting improvement in signs and symptoms of heart failure… with definite improvement of quality of life.”

Another found that when combined with conventional therapies, patients saw a “16% reduction in LDL cholesterol, a 15% decrease in cholesterol, and an 11% decrease in triglycerides” over pharmaceutical drugs alone.

The same review found that across the studies they found some instances of lesser side effects like stomach upset and headache when doses of between one and two grams were used. (3)

Because high blood sugar can damage the heart over time, Tribulus terrestris is of particular interest for those who have diabetes.

Over a three month period, researchers studied non-insulin dependent women with Diabetes type 2. They concluded there was a reduction in both total cholesterol and LDL cholesterol, in addition to lowering blood glucose in the patients treated with T. Terrestris (4). Another study in mice supported this finding, noting that there was a reduction in both blood glucose and serum cholesterol (5).

Ayush Herbs Carditone Study

Conducted over six months, researchers wanted to establish the safety, efficacy, and potential side effects of long term use of Ayush Herbs Carditone in patients with hypertension (high blood pressure). Participants were excluded if they had a history of heart disease, bowel disease, depression, as well as other serious illnesses.

The results of the study were a “significant decrease in systolic and diastolic blood pressure” that were also “clinically meaningful”. They also noted a modest but significant increase in potassium they found “ clinically interesting and potentially related to modulation of blood pressure.

The researchers concluded the results “suggest that the investigated dietary supplement is safe for long-term use in adults with prehypertension and stage I hypertension” (6).

There were no serious adverse events cited during the duration of the study. The most common side effects cited as a reason to stop treatment were nasal congestion (three participants) and lightheadedness/tiredness (three participants). The researchers noted that allergies may be a contraindication when using Carditone, increasing nasal congestion.

The results of these studies suggest that Ayush Herbs Carditone may help keep your heart healthy by reducing blood pressure, reducing total cholesterol and LDL cholesterol, and keeping oxidative stress of tissue at bay. As always, consult with your doctor, especially if you have prior conditions or are taking medications.

Click here to try Ayush Herbs Carditone today!


Thank you for taking the time to read Ayush Herbs Carditone Review: Ingredients, Side Effects & More

Please note: All information presented to you in this website is intended for your general knowledge only and is not a substitute for medical advice or treatment for specific medical conditions. We cannot, and will not give you medical advice. We strongly recommend you consult your physician for any and all specific health issues. If you have any questions or contributions, please contact us via email or phone-call. We are constantly looking for new information to promote wellness – and hearing from you would make our day.

Live Vibrantly!

  1. Chemical composition, antioxidant potential, macromolecule damage and neuroprotective activity of Convolvulus pluricaulis
  2. Rauwolfia in the Treatment of Hypertension
  3. Medicinal properties of Terminalia arjuna (Roxb.) Wight & Arn.: A review – ScienceDirect
  4. Efficacy of the Hydroalcoholic Extract of Tribulus terrestris on the Serum Glucose and Lipid Profile of Women With Diabetes Mellitus: A Double-Blind Randomized Placebo-Controlled Clinical Trial
  5. Hypoglycemic effect of saponin from Tribulus terrestris
  6. Prospective Safety Evaluation of a Cardiovascular Health Dietary Supplement in Adults with Prehypertension and Stage I Hypertension]

Side effects of creatine

Creatine is a nitrogen rich carboxylic acid. The human body synthesizes a substance from glycine, methionine, arginine. In sports, creatine is used by athletes to develop strength characteristics and increase muscle mass. The supplement increases training time and endurance.
It can be obtained naturally from red meat. It is low in fruits and vegetables. Therefore, vegetarians are deficient in creatine and need to replenish their need for it from dietary supplements or sports nutrition. The most common formula of the substance is monohydrate. There are many products based on, there are both pure creatine monohydrate and complex products with transport systems.

Creatine types

The modern industry of sports nutrition is developed quite well and the range of sports nutrition types is growing, and the number of types within each type is also growing. Most often, the reason for the emergence of new types of products is marketing and the search for uniqueness. However, the classic form, which is creatine monohydrate, often remains the most effective.

Side effects

Creatine is a safe supplement. This is supported by scientific studies in which the dosage of 25 g/day did not cause any side effects. However, depending on the individual characteristics of the body, sometimes there are side effects from the use of creatine.

1. Water retention. The most important side effect is related to the ability of creatine to retain water. By itself, this effect is not dangerous for the body, but for all bodybuilders it is very important to have relief muscles and they use diuretics in order to remove excess water – they “dry”. Which in turn can harm the body, due to lack of fluid, the consequences can be very different. Therefore, be careful not to use diuretics.

2. Violations of the digestive tract. During the loading period (i.e. the maximum dosage of creatine), some people experience gastrointestinal disturbances, in particular nausea, diarrhea, etc. It depends on the quality of the creatine supplement. At the same time, many manufacturers for advertising purposes indicate that new forms of creatine do not cause side effects in the gastrointestinal tract, however, apparently this is not confirmed by studies. Side effects on the gastrointestinal tract are observed regardless of the form of creatine. The correct solution in this situation would be a slight decrease in dosage during the loading period or the use of other methods of administration, which you can read about in our article.

3. Seizures. There is information about muscle cramps and sometimes this information is replicated by the media, however, creatine does not affect cramps, cramps can be due to dehydration from 1 point. Therefore, creatine has nothing to do with seizures.

4. Acne. A very rare side effect, but again, it is not associated with creatine, but with an increase in testosterone synthesis.

5. Myths. There is information about side effects on the liver, kidneys, cardiovascular system, potency, as well as a carcinogenic effect, but all these are products of unscrupulous information portals and yellow press. All this information is not true.

Terminals

Creatine is indeed a safe supplement, however many occasionally try to attribute the side effects to creatine for the sake of the hype. Confirmed side effects are extremely rare and are not associated with creatine itself, but with the wrong attitude to the body in athletes. The only thing you need to know is that creatine slightly retains water, it does not affect the body in any way, it does not cause any swelling, however, after the end of the course, this water will also leave the body and you will lose about 20% of the weight gained during this period. In our online store you can choose the creatine that is right for you.

Authors:

Tokaev Enver Saidovich details
Khasanov Adam Alievich


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Creatine side effects, harms and health benefits

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    Creatine is considered the safest sports nutrition supplement. This compound is credited with a lot of positive qualities and effects. However, under certain circumstances, creatine can still be harmful to health.

    Before you start taking the drug, you should understand what creatine is, learn about its contraindications and side effects.

    Side effects of creatine

    The supplement has no irreversible harmful effects. Adverse reactions, which are temporary, occur in 4% of athletes. The drug has undergone many studies, including the use of high dosages. The test subjects showed no abnormalities during the experiment.

    In most cases, side effects are not due to creatine itself, but due to the auxiliary elements that are part of the supplements. But the substance “in its pure” form can cause unwanted reactions – it all depends on the individual characteristics of the athlete’s body.

    Fluid retention

    This phenomenon cannot be called a side effect in the truest sense of the term. This is a compensation that restores the alkaline balance. It is observed in almost every athlete taking creatine. However, this is not visually noticeable.

    Do not take diuretics and reduce fluid intake to prevent water retention. This will lead to adverse consequences. Moreover, many trainers advise to increase the daily water intake.

    Dehydration

    Creatine saturates muscle tissue, but the body itself is dehydrated. There are problems with metabolic processes, acid-base balance, thermoregulation. To avoid pathological phenomena, you need to consume at least 3 liters of fluid per day.

    In bodybuilding, sometimes a dangerous cutting regimen is used: they take creatine with diuretics and stimulants. Such an approach causes significant harm.

    Digestion

    On the part of the gastrointestinal tract, nausea, problems with stools may occur. Often the stomach hurts. This is due to poor dissolution of creatine crystals that have not undergone the necessary purification. However, now the quality of the produced additives is monitored especially carefully, and such side effects are extremely rare.

    Muscle spasms

    The notion that creatine causes spasms and cramps is wrong. Such symptoms do occur when taking a sports supplement, but they are due to other reasons. Involuntary muscle contraction occurs as a result of dehydration. It can also be a recovery reaction during rest: the phenomenon often occurs after intense physical exertion.

    Skin problems

    Acne rarely occurs when taking creatine. Usually the formation of acne is due to an increase in the production of testosterone, and this, albeit indirectly, but affects the intensive set of muscle mass and can be considered a good indicator.

    Many experts are convinced that the appearance of acne has nothing to do with taking creatine – it’s just a matter of increased training and changes in hormonal levels.

    Effects on organs

    Healthy kidneys are not affected by creatine, but the substance can aggravate diseases of these organs, in particular, kidney failure (this has not been scientifically proven).

    Creatine is a naturally synthesized substance. It is necessary to take it, since the amount that the body produces on its own is most often not enough to gain muscle mass.

    The only desired side effect

    The positive side effect of creatine is an increase in muscle mass from 0.9 to 1.7 kg. There are two assumptions for what reason this effect is observed:

    • the substance retains fluid in the muscles;
    • muscle mass itself grows.

    Scientists did not agree here either. Some believe that the side effect is due to two factors at once.

    © shalunx13 — depositphotos.com

    Men and creatine

    Creatine is said to be bad for the male reproductive system, leading many to stop taking supplements. Such a myth is the result of bitter experience in the use of hormone-based products. They really caused sexual dysfunction. Conducted studies regarding creatine have not revealed a relationship between the substance and potency. Therefore, fears are absolutely not justified. Nevertheless, it is not recommended to use the supplement without consulting a trainer and a doctor.

    Follow the instructions for use when taking the supplement. Do not exceed prescribed dosages. Buy the drug only in specialized stores.

    False side effects

    Creatine does not affect the genitourinary system. It also does not have the following side effects attributed to it:

    • does not increase intravenous pressure;
    • is not carcinogenic;
    • does not overburden the heart;
    • does not cause a dependency.

    Gained muscle mass is maintained by 70-80%. The remaining percentage is excreted with excess fluid.

    Benefit

    • lowers “bad” cholesterol;
    • contributes to the rapid recovery of muscle tissue after intensive growth and strong physical exertion;
    • helps with atrophic changes and weakness of the muscular corset;
    • has an anti-inflammatory effect;
    • helps build muscle mass;
    • improves brain activity;
    • restores hair.

    Despite the many useful properties, the supplement should not be abused.

    Abuse

    Cases of overdose of the substance have not been identified so far.

    When the drug is abused, the excess is eliminated from the body on its own. Cretin is excreted by the kidneys together with excess fluid.

    Contraindications

    Sports supplement has a number of contraindications:

    • substance intolerance;
    • old age;
    • severe diseases of the liver, kidneys, gastrointestinal tract of a chronic nature;
    • bronchial asthma;
    • pregnancy and breastfeeding;
    • minor age (adversely affects the formation and development of the body, worsens the activity of the myocardium and endocrine system).

    To minimize the possibility of adverse reactions, follow these recommendations:

    1. If you have a tendency to allergies, visit a specialist and have compatibility tests before use.
    2. Please read the packaging carefully before purchasing. If the components contain a component that can provoke an allergic reaction, the purchase should be abandoned.
    3. Do not use with antihistamines. If an allergy occurs, the course of taking creatine should be stopped and a visit to the hospital should be made.

    There is an opinion that a biological additive is addictive (same as psychotropic substances), but this is not true. With continued use, a habit is formed. However, it has nothing similar to drug addiction. The body simply stops synthesizing creatine on its own.

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      Scientific consultant of the project.
      Physiologist (Faculty of Biology, St. Petersburg State University, Bachelor’s degree).
      Biochemist (Faculty of Biology, St. Petersburg State University, master’s degree).
      Hatha yoga instructor (Institute for Human Resource Development Management, GENERATION YOGA project).