What are the main uses of sodium chloride in medical settings. How should sodium chloride be administered safely. What are the potential side effects and precautions for sodium chloride use. When might a doctor prescribe sodium chloride.

Understanding Sodium Chloride and Its Medical Applications

Sodium chloride, commonly known as salt, plays a crucial role in various medical applications. It’s used in both oral and injectable forms to address different health concerns and maintain proper bodily functions.

What is sodium chloride?

Sodium chloride is a chemical compound consisting of sodium and chloride ions. In medical settings, it’s utilized to replenish electrolytes, maintain fluid balance, and treat various conditions.

Why is sodium chloride important for the body?

Sodium chloride is essential for:

• Regulating blood pressure
• Maintaining proper nerve and muscle function
• Balancing body fluids
• Supporting the transmission of electrical signals in the body

Oral Sodium Chloride: Uses and Administration

Oral sodium chloride is typically prescribed in tablet or solution form for specific medical purposes.

What are the primary uses of oral sodium chloride?

Oral sodium chloride is commonly used to:

• Supply water and salt to the body
• Prevent heat cramps caused by excessive sweating
• Treat certain electrolyte imbalances

How should oral sodium chloride be taken?

To ensure safe and effective use of oral sodium chloride:

1. Follow all directions on the product package or as prescribed by your doctor
2. Check the ingredients, even if you’ve used the product before, as manufacturers may change formulations
3. Consult your doctor or pharmacist if you have any questions about usage

Injectable Sodium Chloride: Applications and Administration

Injectable sodium chloride, including intravenous (IV) infusions, is used in various medical settings to address more acute or severe conditions.

When is injectable sodium chloride used?

Injectable sodium chloride is commonly employed in:

• Treating dehydration
• Correcting electrolyte imbalances
• Diluting other medications for IV administration
• Managing certain types of metabolic alkalosis

How is injectable sodium chloride administered?

Injectable sodium chloride is typically administered by healthcare professionals in clinical settings. The dosage and rate of administration are carefully calculated based on the patient’s specific needs and condition.

Potential Side Effects of Sodium Chloride

While sodium chloride is generally safe when used as directed, it can cause side effects in some individuals.

What are common side effects of sodium chloride?

Common side effects may include:

• Swelling of hands, ankles, or feet
• Nausea or vomiting
• Stomach discomfort
• Increased thirst

Are there any serious side effects to be aware of?

Serious side effects, though rare, may include:

• Severe allergic reactions (rash, itching, swelling of face/tongue/throat)
• Difficulty breathing
• Chest pain
• Irregular heartbeat

If you experience any of these serious side effects, seek immediate medical attention.

Precautions and Considerations for Sodium Chloride Use

Before using sodium chloride, it’s important to consider certain precautions and inform your healthcare provider of any relevant medical conditions or medications.

Who should exercise caution when using sodium chloride?

Individuals with the following conditions should use sodium chloride with caution:

• Kidney problems
• Heart conditions (such as heart failure)
• High blood pressure
• Liver disease
• Edema (fluid retention)

Is sodium chloride safe during pregnancy and breastfeeding?

Sodium chloride is generally considered safe during pregnancy and breastfeeding when used as directed. However, it’s essential to consult with your healthcare provider before use to ensure it’s appropriate for your specific situation.

Drug Interactions with Sodium Chloride

Sodium chloride can interact with various medications, potentially altering their effectiveness or increasing the risk of side effects.

Which medications may interact with sodium chloride?

Potential interactions may occur with:

• Certain blood pressure medications
• Corticosteroids
• Lithium
• Some diuretics

Always inform your healthcare provider about all medications, supplements, and herbal products you’re taking to avoid potential interactions.

Proper Storage and Handling of Sodium Chloride Products

Proper storage and handling of sodium chloride products are crucial for maintaining their efficacy and safety.

How should sodium chloride products be stored?

For optimal storage:

• Keep at room temperature away from light and moisture
• Avoid storing in the bathroom
• Keep out of reach of children and pets
• Do not use after the expiration date

How should unused or expired sodium chloride be disposed of?

To properly discard sodium chloride:

1. Do not flush down the toilet or pour into drains unless instructed to do so
2. Consult your pharmacist or local waste disposal company for proper disposal methods
3. Follow any specific disposal instructions provided on the product packaging

Monitoring and Follow-up Care for Sodium Chloride Use

Regular monitoring and follow-up care are essential when using sodium chloride, especially for long-term or high-dose treatments.

What types of monitoring may be required?

Your healthcare provider may recommend:

• Regular blood tests to check sodium levels
• Blood pressure monitoring
• Kidney function tests
• Electrolyte balance assessments

How often should follow-up appointments be scheduled?

The frequency of follow-up appointments will depend on your individual health status and the reason for sodium chloride use. Your healthcare provider will determine an appropriate schedule based on your specific needs.

Sodium chloride plays a vital role in maintaining various bodily functions and treating certain medical conditions. Whether used in oral or injectable form, it’s crucial to follow proper administration guidelines and be aware of potential side effects and interactions. Regular monitoring and open communication with your healthcare provider are key to ensuring safe and effective use of sodium chloride products.

By understanding the uses, precautions, and proper handling of sodium chloride, patients can make informed decisions about their health and work collaboratively with their healthcare providers to achieve optimal treatment outcomes. As with any medication or medical treatment, it’s essential to consult with a qualified healthcare professional for personalized advice and guidance.

Sodium Chloride – Oral | HealthLink BC

Uses

This product is used to supply water and salt (sodium chloride) to the body. It may also be used to prevent heat cramps due to excessive sweating.

Check the ingredients on the label even if you have used the product before. The manufacturer may have changed the ingredients. Also, products with similar names may contain different ingredients meant for different purposes. Taking the wrong product could harm you.

How To Use

Follow all directions on the product package. If your doctor has prescribed this medication, take it as directed. If you have any questions, ask your doctor or pharmacist.

If your condition lasts or gets worse, or if you think you may have a serious medical problem, get medical help right away.

Side Effects

If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including:

• swelling of hands/ankle/feet

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:

• rash
• itching/swelling (especially of the face/tongue/throat)
• severe dizziness
• trouble breathing

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US –

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking sodium chloride, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of:

• kidney problems
• heart problems(such as heart failure)
• high blood pressure

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Sodium chloride is safe to use during pregnancy or while breastfeeding when used as directed.

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Notes

Keep all regular medical and lab appointments.

Lab tests (such as sodium blood levels) may be done while you are taking this medication. Keep all medical and lab appointments. Consult your doctor for more details.

Missed Dose

If you are taking this product on a regular schedule and miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Sodium Chloride Injection and Intravenous Infusion ( ) Drug / Medicine Information

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NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia.

INJECTION & INTRAVENOUS INFUSION

CONSUMER MEDICINE INFORMATION

What is in this leaflet

This leaflet answers some common questions about Sodium Chloride Injection and Sodium
Chloride Intravenous Infusion. It does not contain all the available information.
It does not take the place of talking to your doctor or pharmacist.

All medicines have benefits and risks. Your doctor has weighed the risks of you being
given Sodium Chloride Injection or Sodium Chloride Intravenous Infusion against the
benefits they expect it to have for you.

This medicine is likely to be used while you are at the clinic or in hospital. If
possible, please read this leaflet carefully before this medicine is given to you.
In some cases this leaflet may be given to you after the medicine has been used.

If you have any concerns about using this medicine, ask your doctor or pharmacist.

Keep this leaflet.

You may need to read it again.

What SODIUM CHLORIDE INJECTION and SODIUM CHLORIDE INTRAVENOUS INFUSION are used for

Sodium Chloride Injection and Sodium Chloride Intravenous Infusion are given to patients
who have low levels of sodium or chloride. These chemicals are naturally present in
body fluids and are needed for normal body function.

Sodium Chloride Injection and Sodium Chloride Intravenous Infusion may also be used
for the dilution of other medicines before injecting into the body.

Sodium Chloride Injection and Sodium Chloride Intravenous Infusion may be used for
the management of other conditions that are not mentioned above. Your doctor will
be able to tell you about the specific condition for which you have been prescribed
Sodium Chloride.

This medicine is available only with a doctor’s prescription.

Before you are treated with SODIUM CHLORIDE INJECTION or SODIUM CHLORIDE INTRAVENOUS
INFUSION

When you must not be given it

It may not be safe for you to be given sodium chloride. If you are not sure, check
with your doctor.

Do not use it after the expiry date (EXP) printed on the label.

Do not use if the packaging is torn or shows signs of tampering.

Do not use unless the solution is clear and the seal is intact.

Before you are given it

Tell your doctor if:

1. you have any allergies to:

any other medicine

any other substances, such as foods, preservatives or dyes

2. you are pregnant or intend to become pregnant

your doctor will discuss the possible risks and benefit of being given Sodium Chloride
Injection or Intravenous Infusion during pregnancy.

3. you are breastfeeding or plan to breast feed

it is not known whether sodium chloride passes into breast milk. Discuss with your
doctor the risks and benefits being given Sodium Chloride Injection or Intravenous
Infusion whilst breastfeeding.

4. you have or have had any medical conditions, especially the following:

heart disease

kidney problems

liver disease

swelling of the hands, ankles or feet

breathlessness, which may be severe and usually worsens when lying down

any condition for which you are taking corticosteroids or corticotrophin

Taking other medicines

Tell your doctor if you are taking any other medicines, including any that you buy
without a prescription from your pharmacy, supermarket or health food shop.

Some medicines may affect the way sodium chloride works. Your doctor will advise you
about continuing to take other medicines.

How SODIUM CHLORIDE INJECTION or SODIUM CHLORIDE INTRAVENOUS INFUSION is given

Sodium Chloride Injection may be given as an injection and Sodium Chloride Intravenous
Infusion given through slow injection into your veins (this is called an intravenous
infusion). Both will be given by your doctor or a specially trained nurse.

Your doctor will decide what dose, how often and how long you will receive it. This
depends on your condition and other factors, such as your weight, age, blood tests,
how well your kidneys are working, and whether or not other medicines are being given
at the same time.

Follow all directions given to you by your doctor and pharmacist carefully.

These directions may differ from the information contained in this leaflet.

Never administer this medicine yourself.

If you are given too much (overdose)

This rarely happens as Sodium Chloride Injection and Sodium Chloride Intravenous Infusion
are administered under the care of a highly trained doctor or nurse.

However, if you are given too much sodium chloride you may experience some of the
effects listed under “Side Effects” below.

Your doctor has information on how to recognise and treat an overdose. Ask your doctor
if you have any concerns.

Side effects

Tell your doctor or nurse as soon as possible if you do not feel well while you are
being given Sodium Chloride Injection or Sodium Chloride Intravenous Infusion.

Like other medicines, sodium chloride can cause some side effects. If they occur,
most are likely to be minor or temporary. However, some may be serious and need medical
attention.

Ask your doctor or nurse to answer any questions that you may have.

Do not be alarmed by this list of possible side effects. You may not experience any
of them.

Tell your doctor immediately if you notice any of the following:

fast heart beat

difficulty breathing

headache or dizziness

sleepiness, drowsiness or confusion

These may be serious side effects. You may need urgent medical attention. Serious
side effects are rare.

Tell your doctor if you notice any of the following and they worry you:

nausea and vomiting

stomach cramps

diarrhoea

thirst, dry mouth

sweats

swelling of the hands, ankles or feet

muscle twitches, weakness or cramps

restlessness or irritability

fever

watery eyes

reduced saliva or dry eyes

These are the more common side effects of sodium chloride. Mostly these are mild and
short-lived.

Other side effects not listed above may also occur in some patients. If you notice
any other effects, check with your doctor. Some side effects may only be seen by your
doctor.

Storage

Sodium Chloride Injection and Sodium Chloride Intravenous Infusion should be stored
below 25°C.

Product Description

What it looks like

Sodium chloride 0.9% solution as Sodium Chloride Injection and Sodium Chloride Intravenous
Infusion is a clear, colourless solution contained in plastic ampoules or vials.

Sodium Chloride products can be identified by an Australian Register Number which
is found on the packaging:

Ampoules: AUST R 49272, AUST R 49278 and AUST R 49279

Vials: AUST R 10804 and AUST R 49280

Ingredients

Sodium Chloride Injection and Sodium Chloride Intravenous Infusion contain sodium
chloride in Water for Injections. They do not contain a preservative.

Sponsor and Distributor in Australia

Pfizer Australia Pty Ltd

Sydney, NSW

Date of preparation

This leaflet was prepared in August 2021.

^® Registered trademark

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Sodium chloride (Sodium chloride): description, recipe, instruction

Sodium chloride

Analogues (generics, synonyms)

Voluven, Acesol, Reopoliglyukin, Gelatinol, Gelofusin, Disol, Regidron, Rheosorbilact, Polyglucin, Moviprep 00, Artificial Tears, mNeurocytin, Ophthalmosol, Polydextran, Promit-Infusion, Allergen Dissolving Liquid, Re-Sol, Regidron Optim, Ringer’s, Rhinolux, Salin, Septoaqua Adult, Hartman Without Magnesium, Extraneal, Endofalk

Active ingredient

Sodium chloride (Natrii chloridum)

Pharmacological group

org/DrugClass”>
Regulators of water-electrolyte balance and KShchS

Recipe

International:

Rp.: Solutionis Natrii chloridi isotonicae 0.9% – 500 ml
D. S. Intravenous (drip) 1 bottle 1 time per day

Rp.: Sol. Natrii chloridi 9 mg/ml 10 ml

D.t.d. No. 10 in amp.
S. For dilution of medicinal substances

Russia:

Prescription form 107-1/u

Pharmacological action

Hydrating, detoxifying, normalizing acid-base balance, plasma-substituting.

Pharmacodynamics

The pharmacodynamic properties of the solution are due to the presence of sodium ions and chloride ions. A number of ions, including sodium ions, penetrate the cell membrane using various transport mechanisms, among which the sodium-potassium pump (Na-K-ATPase) is of great importance. Sodium plays an important role in signaling in neurons, electrophysiological processes in the heart, and also in metabolic processes in the kidneys.

Pharmacokinetics

The concentration of sodium ions is 142 mmol/l (plasma) and 145 mmol/l (interstitial fluid), the concentration of chloride is 101 mmol/l (interstitial fluid). Excreted by the kidneys.

How to use

For adults:

Isotonic sodium chloride solution is injected intravenously, s / c and in enemas, and is also used to wash wounds, eyes, nasal mucosa. More often administered intravenously, depending on the clinical situation – up to 3 l / day.
Hypertonic sodium chloride solution is administered intravenously. A single dose for intravenous jet administration can be 10-30 ml. In conditions requiring immediate replenishment of sodium and chlorine ions, the drug is administered intravenously in a dose of 100 ml.
Topically and externally used depending on the dosage form used and the treatment regimen.

For children:

Children with a pronounced decrease in blood pressure against the background of dehydration (until laboratory parameters are determined) are administered 20-30 ml / kg. In the future, the dosing regimen is adjusted depending on laboratory parameters.

Readings

– isotonic extracellular dehydration;
– hyponatremia;
– dilution and dissolution of parenterally administered medicinal substances (as a stock solution).

Contraindications

– hypernatremia;
– acidosis;
– hyperchloremia;
– hypokalemia;
– extracellular hyperhydration;
– intracellular dehydration;
– circulatory disorders, threatening swelling of the brain and lungs;
– cerebral edema;
– pulmonary edema;
– acute left ventricular failure;
– concomitant administration of large doses of corticosteroids.

Special instructions

During any infusion, it is necessary to monitor the patient’s condition, clinical and biological parameters, it is especially important to evaluate plasma electrolytes. In children, the immaturity of kidney function may slow sodium excretion. Therefore, in such patients, repeated infusions should be carried out only after determining the concentration of sodium in the plasma.

Use only clear solution, free of visible impurities, unless package is damaged. Enter immediately after connecting to the infusion system. Do not use series connection of plastic containers. This can lead to an air embolism due to the suction of air remaining in the first container, which can occur before the solution from the next container arrives. The solution should be administered using sterile equipment in compliance with the rules of asepsis and antisepsis. To prevent air from entering the infusion system, it should be filled with solution, releasing the residual air from the container completely. You can add other drugs to the solution before or during the infusion by injection into a specially designated area of ​​​​the container.

As with all parenteral solutions, the compatibility of the added substances with the solution must be determined before reconstitution.

Must not be used with sodium chloride solution 0.9% preparations known to be incompatible with it. The compatibility of the added medicinal substances with a solution of sodium chloride 0.9% should be determined by the doctor by checking for a possible change in color and / or the appearance of a precipitate, insoluble complexes or crystals.

Before adding, it must be determined whether the substance to be added is soluble and stable in water at a pH level similar to sodium chloride solution 0.9%.

When adding the drug, it is necessary to determine the isotonicity of the resulting solution before infusion. Before adding drugs to the solution, they must be thoroughly mixed in compliance with the rules of asepsis. The prepared solution should be administered immediately after preparation, do not store!

The addition of other drugs or improper administration technique may cause fever due to possible ingestion of pyrogens. In case of development of undesirable reactions, it is necessary to immediately stop the introduction of the solution. Before using the solution, the container should not be removed from the outer protective polypropylene / polyamide bag in which it is placed, as it maintains the sterility of the drug.

Side effects

Acidosis, hyperhydration, hypokalemia.

When used correctly, unwanted effects are unlikely.

When using sodium chloride solution 0.9% as a base solution (solvent) for other drugs, the likelihood of side effects is determined by the properties of these drugs. In this case, if adverse reactions occur, the administration of the solution should be suspended, the patient’s condition should be assessed, adequate measures taken, and the remaining solution should be saved for analysis, if necessary.
If any of the side effects listed in the instructions worsen, or you notice any other side effects not listed in the instructions, tell your doctor.

Overdose

Symptoms: nausea, vomiting, diarrhea, abdominal cramps, thirst, decreased salivation and tearing, sweating, fever, tachycardia, increased blood pressure, renal failure, peripheral edema, pulmonary edema, respiratory arrest, headache, dizziness, anxiety, irritability, weakness, muscle cramps and rigidity, generalized convulsions, coma and death. Excessive administration of the solution can cause hypernatremia.

Excessive intake of chloride in the body can lead to hyperchloric acidosis.

When used as a stock solution for the dilution and dissolution of other drugs, the symptoms and complaints of overdose are most often related to the properties of the drugs administered.

In the event of an inadvertent overdose of the solution, treatment should be discontinued and the patient assessed.

Treatment: symptomatic.

Drug interaction

Not described.

When mixing with other drugs, visually check compatibility. To do this, you should observe the resulting solution for a change in its color and / or precipitation, the appearance of crystals, insoluble complexes. It is also necessary to take into account the instructions for use of the added drugs.

Release form

Solution for infusion 0.9% transparent, colorless.

1 l sodium chloride 9g.
Excipients: water for injection – up to 1 liter.
100 ml – Viaflo containers (50) – cardboard boxes.

Solution for infusion 0.9% clear, colorless.

1 liter sodium chloride 9 g.
Excipients: water for injection – up to 1 liter.
250 ml – Viaflo containers (30) – cardboard boxes.
500 ml – Viaflo containers (20) – cardboard boxes.
1 l – Viaflo containers (10) – cardboard boxes.

Solution for infusion 0.9% clear, colorless.

1 liter sodium chloride 9 g.
Excipients: water for injection – up to 1 liter.
50 ml – Viaflo containers (50) – cardboard boxes.

Solvent for the preparation of dosage forms for injections 0.9%.

5 or 10 ml in polymeric ampoules, produced according to blow-fill-seal technology.
5 or 10 polymer ampoules, together with instructions for medical use, are placed in a pack of cardboard.

recipes

RECIPES

1. Benzylpenicillin

Rp.: Benzylpenicillin-natrii 500000 ED D. t.d. N 50

S. Dissolve the contents of 1 vial in 5 ml of 0.9% sodium chloride solution. Inject 5 ml intramuscularly every 4 hours.

2. Chloramphenicol

Rp.: Tab. Chloramphenicoli 0.25 N10

D.S. Take orally 30 minutes before meals (in case of nausea and vomiting – 1 hour after meals) ½ tab. 4 times a day.

3. Ampicillin

Rp.: Ampicillini – trihydrati 0.25 D.t.d N 20 in caps.

S. 1 capsule 3 times a day after meals.

Rp.: Ampicillini – trihydrati 500000 ED D.t.d. N 10

S. Dissolve the contents of 1 vial in 2.5 ml of 0.9% sodium chloride. 2.5 ml intramuscularly every 8 hours.

4. Amoxicillin

Rp.: Tab. Amoxycillini 0.5 D.t.d N 20

S. 1 tab. 3 times a day. in severe infections, the dose may be increased to 1.0 g 3 times a day.

5. Ceftriaxone

Rp.: Ceftriaxoni 1.0 D. t. d. N 10

S. Dissolve the preparation in 3.5 ml of sterile water for injection. Inject intramuscularly into the upper outer quadrant of the gluteus maximus deep enough.

6. Ceftazidime

Rp: Ceftazidimi 1.0 D. t. d. N 10

S. / m 1.0 after diluting the contents of the vial in 2 ml of isotonic sodium chloride solution.

7. Ceftibuten

Rp.: Tab. Ceftibuteni 0.4 N 20

D.S. take orally, regardless of food intake, 1 tablet 1 time

per day.

8. Ciprofloxacin

Rp: Ciprofloxacini 0.25 D. t. d. No. 20 in tab.

S. 2 tablets 2 times a day. The course of treatment is 7-10 days.

Rp: Sol. Ciprofloxacini 0.2% – 50 ml D. t. d. N 2

S. Enter in / in, pre-dilute in 100 ml of isotonic sodium chloride solution. The course of treatment is 7-10 days.

9. Levofloxacin

Rp.: Tab. Levofloxacini 0.25 N 5

D.S. Take orally between meals or before meals, 2 tablets. 2 r / d. The tablets must not be chewed. Drink 0.5-1 glass of water.

Rp.: Levofloxacini 1.0 D. t. d. No. 5 in flac.

S. in case of bacteremia or septicemia, start with an intravenous infusion of Levofloxacin, and then continue with the tablet form

10. Norfloxacin

Rp.: Tab. Norfloxacini 0.4 N 20

D.S. 1 tab. 2 times a day. Duration of treatment – 7-14 days; if necessary, longer treatment is carried out.

11. Clarithromycin

Rp.: Tab. Clarithromycini 0.25 N 10

D.S. To be taken orally, with or without food. Take 1 table. 2 r / day.

12. Azithromycin (Sumamed)

Rp.: Tab. Azitromycini 0.5 N 3

D.S. 1 tablet 1 time per day after meals for 3 days.

13. Rovamycin

Rp.: Rovamycini 3 million IU D.t.d N 16 in tab.

S. Take 1 tablet orally 2 times a day. The course of treatment is 5-7 days.

14. Doxycycline

Rp.: Doxycyclini hydrochloridi 0.1 D.t.d N 10 in caps.

S. Take 1 capsule orally twice a day after meals.

15. Tetracycline

Rp.: Tab. Tetracyclini hydrochloridi 0.25 No. 20

D.S. 1 tablet 3 times a day after meals.

16. Streptomycin

Rp.: Streptomycini sulfatis 0.5 D.t.d. N 10

S. Dilute the contents of 1 bottle in 2 ml of water for injection (or 2 ml of 0.5% novocaine solution). Enter 2 ml / m 2 times a day.

17. Nifuroxazide

Rp.: Tab. Nifuroxazidi 0.1 No. 24

S. Take 2 tablets every 6 hours, regardless of the meal. The course of therapy is 5-7 days.

18. Furazolidone

Rp.: Tab. Furazolidoni 0.05 N 20

D.S. 2 tablets 4 times a day after meals for 5-7 days.

19. Phthalazol

Rp.: Tab. Phthalazoli 0.5 N 50

D.S. 1st and 2nd day – 2 tablets every 4 hours, 3rd and 4th day – 2 tablets every 6 hours, 5th and 6th day – 2 tablets every 8 hours .

20. Sulfadimethoxine

Rp.: Tab. Sulfadimetoxini 0.5 N 20

D.S. On the 1st day – 4 tablets for 1 dose, from the 2nd to the 6th day – 2 tablets per day.

21.Aciclovir (Zovirax)

Rp.: Tab. Acicloviri 0.2 No. 20

D.S. take 1 tablet 3 times a day for the treatment of herpes. The duration of treatment is 5 days, with herpes zoster – another 3 days after the disappearance of signs of the disease.

22. Oseltamivir (Tamiflu)

Rp.: “Tamiflu 75” N 10

D. S. Inside. Treatment: the drug should be started no later than 2 days from the onset of influenza symptoms; adults and children over 12 years old – 1 capsule 2 times a day for 5 days. Prevention: 1 tablet 1 time per day for 6 weeks (during an influenza epidemic).

23. Amiksin (Tiloron)

Rp.: “Amixin” N 10

D.S. taken orally at the end of the meal. The course of treatment directly depends on the type of disease. In general, the drug for treatment is taken 1 or 2 tablets per day for two days, and then one tablet after 2 days.

Influenza and other acute respiratory viral infections require this drug for one week. Hepatitis A is treated for 2 weeks, and hepatitis B – 3. The course of treatment for neuroviral infections is designed for 3 or 4 weeks, chlamydial, cytomegalovirus and herpetic infections require 4 weeks of treatment. In order to prevent one tablet of amixin drink once a week. The prophylactic course is designed for 4 weeks.

24.Cycloferon

Rp.: Tab. Cycloferoni 0.15 N50

D.S. take orally 1 time per day half an hour before meals, without chewing, according to the basic scheme, 2-4 tablets per dose in 1, 2, 4, 6, 8, 11, 14, 17, 20 , 23 days depending on the nature of the disease.

Rp.: Sol. Cycloferoni 12.5% ​​2 ml D.t.d. N 20 in amp.

S. injects 2 ml intramuscularly or intravenously 1 time per day according to the basic scheme on days 1, 2, 4, 6, 8, 11, 14, 17, 20, 23, 26, 29, depending on the nature of the disease.

25. Groprinosin

Rp.: Tab. Groprinosini 0.5 N50

D.S. treatment of acute respiratory viral infections (influenza and parainfluenza, rhino- and adenovirus infections) – 2 tablets 3-4 times a day. It is necessary to start treatment with Groprinosin as early as possible, already at the first symptoms of the disease and continue for another 1-2 days after the symptoms disappear.

Treatment of cytomegalovirus The daily dosage is calculated based on body weight, and is 50

mg / kg, divided into 3-4 doses, the course of therapy usually lasts 1 month. Treatment of herpes type I

The recommended dose for adults is 2 tablets four times a day, divided into 3-4 doses, the course of treatment is usually 2 weeks.

Treatment of herpes type II The recommended dose in the acute period is 2 tablets three times a day, in

for 5-6 days, then they switch to a maintenance dose of 1 tablet once a day, for six months.

26. Delagil

Rp.: Tab. Delagil 0.25 N 10

D.S. Take orally after meals. In the treatment of malaria, 8-11 tablets are prescribed. for the course of treatment: 4 tablets / first day, after 11-12 hours 2 tablets, for

second and third days – 2-3 tab. for one take. Prevention of malarial infection: 2 tab. 2 times a week, then 2 tablets. 1 time per week.

27. Quinine

Rp.: Tab. Chinini hydrochloridi 0.5 N 10

D. S. Take orally 2 tablets. 2 r / d for 5-7 days.

Rp: Sol. Chinini dyhydrochloridi 50% 1ml

D. S. In case of malignant course of malaria, quinine dihydrochloride is injected deep into the subcutaneous adipose tissue (but not into muscles) on the 1st day 2 ml of a 50% solution of quinine dihydrochloride twice with a break between injections of 68 hours. the first intravenous injection – 0.5 g of quinine dihydrochloride is administered, for which 1 ml of a 50% solution of the drug is diluted in 20 ml of a 40% glucose solution or 20 ml of isotonic sodium chloride solution. Intravenously administered very slowly. The solution is preheated to +35 °C. Following the introduction into the vein, 01 ml of a 50% solution of quinine dihydrochloride is injected into the subcutaneous fatty tissue. The remaining amount of quinine is administered subcutaneously after 68 hours.

28. Primakhin

Rp.: Dr. Primachini 0.009 N100

D.S. Inside, daily dose for adults 0.027 g (3 tablets). The course of treatment is 14 days.

29. Metronidazole

Rp.: Tab. Metronidazoli 0.25 D.t.d. N 20

S. orally 1 tablet 2 times a day for giardiasis.

Rp: Sol. Metronidazoli 0.5%-100ml

D.t.d. N 10

S. in / in drip 100 ml for amebiasis and anaerobic infection

30. Albendazole

Rp .: Tab. Albendazoli 0. 4 N 3

D.S. take 1 tab. 1 r / d for 3 days, drink water. Repeat the course after 3 weeks.

31. Prednisolone

Rp.: Tab. Prednisoloni 0.005 N100

D.S. 2 tab. 4 r / d (in the morning, on an empty stomach, then after a meal) for 6 days, then reduce the dose by ½ tab. Every 4 days at the expense of evening.

Rp.: Sol. Prednisoloni 3% 1 ml D. t. d. N 20 in amp.

S. inject 1 ml 2 times a day / m for 6 days, followed by a dose reduction and the transition to the table.

32. Dexamethasone

Rp.: Tab. Dexamethasoni 0.0005 N 50

D. S. 2 tab. 2 r / d during or after meals for 7 days, then reduce the dose by ½ tab. Every 3 days.

33 Adrenaline hydrochloride

Rp: Sol. Adrenalini hydrochloridi 0.1% – 1 ml D. t. d. N. 6 in amp.

S. inject 0.5 ml subcutaneously.

34. Papaverine

Rp: Sol. Papaverini hydrochloridi 2% 2 ml D. t. d. N 10

S. Under the skin and intramuscularly, 2 ml of a 2% solution is injected, and intravenously – in the same dose (very slowly!), Diluting a 2% solution of papaverine hydrochloride in 10-20 ml of isotonic sodium chloride solution.

35. Platifillin

Rp.: Sol. Platyphyllini hydrotartratis 0.2% 1ml D. t. d. N. 10 in amp.

S. inject 1 ml subcutaneously 3 times a day.

36. No-shpa (drotaverine)

Rp: Nospani 0.04

D. t. d. No. 30 in tab.

S. 1 tablet 2 times a day.

Rp: Tab. Drotaverini 0.04 D. t. d. N 20

S. orally 1 tablet 3 times a day for the treatment of pain.

Rp.: Sol. Drotaverini 2%-2ml

D.t.d. N. 10 in amp.

S. 1 ml IV for the treatment of pain.

37. Duspatalin (Mebeverin)

Rp.: Caps. Duspatalini 0.2 N30

D.S. inside, 20 minutes before meals, without chewing and drinking water – 1 capsule 2 times a day (morning and evening).

38. Furosemide (Lasix)

Rp.: Sol. Furosemidi 1%-2ml D. t. D. N 10 in amp.

S. IM 2 ml 2 times a day. The drug is administered for 7-10 days or more. Then they switch to taking the drug inside.

Rp: Tab. Furosemidi 0.04 N 20

S. orally (in the morning, before meals), at the initial dose of 1-2 tablets; if necessary, it is possible to increase the dose by 20–40 mg (by 1–2 tablets, respectively) every 6–8 hours.

39. Euphyllin

Rp. Euphyuini 2%-5ml D. t. D. N 10 in amp.

S. Intravenously injected slowly (within 4-6 minutes) 5-10 ml of a 2.4% solution, which are pre-diluted in 10-20 ml of isotonic sodium chloride solution.

Rp.: Sol. Euphyuini 24%-1ml

D.t. D. N 10 in amp.

S. If injection into a vein is impossible, 1 ml of a 24% solution is injected intramuscularly.

40. Analgin

Rp.: Sol. Analgini 50% 2ml.

D.t.d. No. 10 in amp

S. IM 1 ampoule 3 times a day

41. Diphenhydramine

Rp.: Sol. Dimidroli 1% 1ml D.t.d. No. 10 in amp

S. IV drip 2 ampoules pre-diluted in 100 ml of 0.9% NaCl solution.

42. Tavegil

Rp.: Tab. Tavegili 0.001 No. 20

D.S. one tablet by mouth twice a day

43. Suprastin

Rp.: Tab. Suprastini 0.025 No. 20

S. inside after eating 1 tab. 2-3 times a day

44. Paracetamol

Rp.: Tab. Paracetamoli 0.2 No. 10

S. inside, 2 tablets. 3-4 times a day

45. Aspirin (acetylsalicylic acid)

Rp.: Tab. Acidum acetylsalicylici 0.25 No. 10 S. inside after meals, 1 tab. 3 times a day

46. Mannitol

Rp.: Sol. Mannitoli 15% 200ml

D.S. intravenously at 0.5-1.5 g / kg in the form of a 10-20% solution of 0.9% NaCl solution.

47. Albumin

Rp.: Sol. Albumini 10% 100ml

D.S. in / in drip or jet at a rate of 50-60 drops per minute. The dose of drug depends on a wedge. pictures, indications and age of the patient. Usually 1-2ml/kg of 10% solution. This dose of the solution is poured every day.

48. Reopoliglyukin

Rp.: Sol. Rheoporygluclni 200ml

D.S. intravenously drip up to 400-100ml.

49. Rheosorbilact

Rp.: Sol. Reosorbilacti 200ml

D.S. Rheosorbilact is administered to adults intravenously by drip or jet. The volume of a single injected solution for shock is 600-1000 ml, for chronic hepatitis – 400 ml, for blood loss – up to 1500 ml, for diseases of the veins and arteries – up to 600 ml.

50. Reamberin

Rp.: Sol. Reamberin 200ml

D.S. Reamberin is used intravenously. Dosage and rate of intravenous infusion is determined individually, depending on the patient’s condition. For adults, the maximum daily dose of the solution is 2 liters.

51. Trisol

Rp.: Sol. Trisoli 200ml

D.S. Intravenous (stream or drip). In severe forms of the disease, they begin with a jet injection of the drug, followed by a transition to a drip.

52. Regidron

Rp.: Rehydroni No. 20

D.S. 1 liter of boiled water is added to the contents of the sachet, then the solution is allowed to cool. Take in small sips after each liquid stool, before use, the solution is thoroughly mixed. It is necessary to drink about 10 ml / kg of body weight per hour, after the dehydration phenomena decrease, the dose of Regidron is reduced to 5-10 ml / kg of the patient’s body weight, after each liquid stool.

53. Essentiale

Rp.: Caps. Essentiali No. 30

D.S. initial dose: 2 capsules 3 times a day, maintenance dose: 1 capsule 3 times a day. Take the capsules during a meal, without chewing, with a small amount of water.

54. Heptral (ademitionin)

Rp.: Tabl. Heptrali 0.4 №20

D.S. initial dose 800 mg/day (2 tab.), total daily dose should not exceed 1600 mg (4 tab.)

55. Legalon (silymarin)

Rp.: Caps. Legaloni 0.14 №100

D.S. first 1 capsule 3 times a day, then 1 capsule 2 times a day.

56. Thiotriazoline

Rp.: Sol. Thiotriazolini 2.5% 2ml D.t.d. No. 10 in amp

S. in / in the drip, having previously dissolved 1 ampoule in 100 ml. 0.9% NaCl solution

57. Calcium gluconate

Rp.: Sol. Calcii gluconasi 10% 5ml D.t.d. No. 10 in amp

S. Intramuscularly and intravenously (slowly) inject 5-10 ml of a 10% solution daily or every 1-2 days

58. Ascorbic acid

Rp.: Sol. Acidum ascorbinlci 10% 1ml D.t.d. No. 10 in amp

S. in / in the drip, 2 ampoules previously diluted in 200 ml of 0.9% NaCl solution.

59. Vit B6

Rp.: Sol. Pyridoxini hydrochloridi 2.5% 1ml D.t.d. No. 10 in amp

S. in / in the drip, 2 ampoules previously diluted in 200 ml of 0.9% NaCl solution.

60. Vitamin B12

Rp.: Sol. Cyanocobalamini 0.05% 1ml D.t.d. No. 10 in amp

S. in / in the drip, 1 ampoule previously diluted in 200 ml 0.9% NaCl solution.

61. Aminocaproic acid

Rp.: Sol. Acldi aminocapronici 5% 100ml D.S. IV drip 100 ml solution

62. Dicynon

Rp.: Tab. Dicynoni 0.25 №100 D.S. 1 tablet 3 times a day

63. Vikasol

Rp.: Sol. Vikasoli 1% 1ml D.t.d. No. 10 in amp

S. IM 1 ampoule 2 times a day

64. Heparin

Rp.: Sol. Heparini sodium 5000 IU 5ml D.t.s No. 5 in flacon

S. The daily dose of heparin (400-450 IU / kg) is diluted in 1200 ml of isotonic sodium chloride solution or Ringer-Locke solution and intravenously at a rate of 20 drops per minute.