9 of The Best Options for Joint Pain

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• Evaluate ingredients and composition: Do they have the potential to cause harm?
• Fact-check all health claims: Do they align with the current body of scientific evidence?
• Assess the brand: Does it operate with integrity and adhere to industry best practices?

We do the research so you can find trusted products for your health and wellness.

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Overview

Many people deal with chronic joint pain in their knees, hands, elbows, shoulders, and elsewhere. In most cases, this is caused by the most common type of arthritis, osteoarthritis. This form of arthritis affects almost one-quarter of people in the United States.

Pain relievers such as acetaminophen (Tylenol) or nonsteroidal anti-inflammatory drugs, such as ibuprofen (Advil), are usually the first choice for joint pain relief.

There are also dozens of supplements that claim to treat joint pain, but which ones actually work? Here’s a look at 9 of the best options and what the existing research says about them.

Turmeric is one of the most popular supplements for treating pain, including joint pain caused by osteoarthritis. Its pain-relieving effects are attributed to a chemical compound in turmeric called curcumin. Curcumin seems to have anti-inflammatory effects.

Although research on turmeric for joint pain is limited, an analysis of studies found that it improves symptoms of joint pain more than a placebo and may be comparable to ibuprofen.

Try it: Turmeric is usually taken in a dose of 500 mg two to four times daily. You can find turmeric supplements at Care/of.

Learn more about the benefits of turmeric and curcumin.

SHOP NOW AT CARE/OF

Fish oil contains the omega-3 fatty acids docosahexaenoic acid and eicosapentaenoic acid, which have anti-inflammatory effects.

An analysis of clinical research shows that taking fish oil supplements reduces symptoms such as joint pain in those with rheumatoid arthritis. But it doesn’t seem to reduce osteoarthritis symptoms.

Try it: Typical fish oil doses range from 300 to 1,000 mg per day. You can find fish oil supplements at Care/of.

SHOP NOW AT CARE/OF

Glucosamine is natural component of cartilage, a substance that prevents bones from rubbing against each other and causing pain and inflammation. It might also help prevent the cartilage breakdown that can happen with arthritis.

Many supplements aimed at treating joint pain contain glucosamine, which is one of the most well-studied supplements for osteoarthritis. But despite this research, there are still some questions about how well it works.

There are two types of glucosamine found in supplements: glucosamine hydrochloride and glucosamine sulfate.

One meta-analysis found that products containing glucosamine hydrochloride don’t do much to improve joint pain caused by osteoarthritis. Another study shows that glucosamine sulfate does improve these symptoms, so it may be a better option that glucosamine hydrochloride.

When taken over a long period of time, glucosamine sulfate may also help to slow down the progression of osteoarthritis. Studies suggest that it slows down narrowing of the joint space, a marker of the condition getting worse, when taken for up to three years.

Try it: Glucosamine sulfate is typically taken once daily in a dose of 1,500 milligrams (mg). If this upsets your stomach, try spreading it out over three doses of 500 mg each. You can find glucosamine sulfate supplements on Amazon.

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Like glucosamine, chondroitin is a building block of cartilage. It may also help prevent cartilage breakdown from osteoarthritis.

Many clinical studies have found that chondroitin can reduce joint pain and stiffness in people with osteoarthritis. About 53 percent of people who take chondroitin have a 20 percent or greater improvement in knee pain.

Chondroitin sulfate may also slow down the progression of osteoarthritis when taken long-term. Studies show that it slows down narrowing of the joint space when taken for up to 2 years.

Joint supplements often combine chondroitin with glucosamine. But it’s still unclear if taking a combination supplement is any better than taking one or the other on their own.

Try it: Chondroitin is typically taken in a dose of 400 to 800 mg two or three times per day. You can find chondroitin supplements on Amazon.

SHOP NOW ON AMAZON

S-adenosyl-L-methionine (SAMe) is a supplement commonly used to help with symptoms of depression and osteoarthritis. Your liver naturally produces SAMe from an amino acid called methionine. It has several functions, including helping the production and repair of cartilage.

When taken as a supplement, SAMe can help with symptoms of joint pain caused by osteoarthritis. It may be as effective as the anti-inflammatory drug celecoxib (Celebrex). In one study from 2004, celecoxib improved symptoms more than SAMe after a month of treatment. But by the second month, the treatments were comparable.

Try it: SAMe is usually taken in doses of 200 to 400 mg three times per day. Keep in mind that it may take some time to notice results. You can find SAMe supplements on Amazon.

SHOP NOW ON AMAZON

Boswellia, also known as Indian frankincense, is commonly used for pain caused by arthritis. Chemicals in this extract called boswellia acids have anti-inflammatory effects.

Clinical studies have shown that boswellia extracts improve pain symptoms more than a placebo in people with osteoarthritis.

Try it: Studies looking at the use of boswellia for joint pain have used doses ranging from 100 mg once per day to 333 mg three times per day. You can find boswellia supplements on Amazon.

SHOP NOW ON AMAZON

Avocado-soybean unsaponifiables (ASUs) refer to a type of extract from avocado and soybean oils that might help prevent the breakdown of cartilage. It may also help to repair cartilage.

Clinical studies show that ASUs improve pain symptoms more than placebo in people with osteoarthritis.

Try it: The typical dose of ASU is 300 mg per day. You can find ASU supplements on Amazon.

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Devil’s claw, also called harpagophytum, contains a chemical called harpogoside that has anti-inflammatory effects.

Taking devil’s claw may help with joint pain from osteoarthritis. In one study, devil’s claw worked about as well as an anti-inflammatory drug called diacerein. However, since there isn’t much research on this supplement for osteoarthritis, more high-quality studies are necessary.

Try it: Most studies involving devil’s claw have used doses of 600 to 800 mg three times per day. You can find devil’s claw supplements on Amazon.

SHOP NOW ON AMAZON

Methylsulfonylmethane (MSM) is another common ingredient in supplements said to help with joint pain.

In one study, MSM improved pain and functioning compared to a placebo in people with osteoarthritis.

Try it: Typical MSM doses range from 1,500 to 6,000 mg per day, sometimes divided into two doses. You can find MSM supplements on Amazon.

SHOP NOW ON AMAZON

Choosing a supplement for joint pain can be overwhelming with the number of products available. Many of these products contain multiple ingredients. Keep in mind that a long ingredient list doesn’t always make for a better product. Also, these products are not regulated by the U.S. Food and Drug Administration so read labels carefully.

In some cases, added ingredients don’t have any proven benefits for joint health. Others might contain multiple beneficial ingredients, such glucosamine and chondroitin. But there’s not much proof that taking supplements containing multiple ingredients is more effective than taking a single ingredient. Plus, some of these products have too little of one or more ingredients for them to be beneficial.

Before choosing a supplement, talk with your doctor or pharmacist about other medications you’re taking so they can check for potential interactions. Some joint health supplements can interact with certain medications, such as blood thinners.

9 of The Best Options for Joint Pain

We include products we think are useful for our readers. If you buy through links on this page, we may earn a small commission Here’s our process.

Healthline only shows you brands and products that we stand behind.

Our team thoroughly researches and evaluates the recommendations we make on our site. To establish that the product manufacturers addressed safety and efficacy standards, we:

• Evaluate ingredients and composition: Do they have the potential to cause harm?
• Fact-check all health claims: Do they align with the current body of scientific evidence?
• Assess the brand: Does it operate with integrity and adhere to industry best practices?

We do the research so you can find trusted products for your health and wellness.

Read more about our vetting process.

Was this helpful?

Overview

Many people deal with chronic joint pain in their knees, hands, elbows, shoulders, and elsewhere. In most cases, this is caused by the most common type of arthritis, osteoarthritis. This form of arthritis affects almost one-quarter of people in the United States.

Pain relievers such as acetaminophen (Tylenol) or nonsteroidal anti-inflammatory drugs, such as ibuprofen (Advil), are usually the first choice for joint pain relief.

There are also dozens of supplements that claim to treat joint pain, but which ones actually work? Here’s a look at 9 of the best options and what the existing research says about them.

Turmeric is one of the most popular supplements for treating pain, including joint pain caused by osteoarthritis. Its pain-relieving effects are attributed to a chemical compound in turmeric called curcumin. Curcumin seems to have anti-inflammatory effects.

Although research on turmeric for joint pain is limited, an analysis of studies found that it improves symptoms of joint pain more than a placebo and may be comparable to ibuprofen.

Try it: Turmeric is usually taken in a dose of 500 mg two to four times daily. You can find turmeric supplements at Care/of.

Learn more about the benefits of turmeric and curcumin.

SHOP NOW AT CARE/OF

Fish oil contains the omega-3 fatty acids docosahexaenoic acid and eicosapentaenoic acid, which have anti-inflammatory effects.

An analysis of clinical research shows that taking fish oil supplements reduces symptoms such as joint pain in those with rheumatoid arthritis. But it doesn’t seem to reduce osteoarthritis symptoms.

Try it: Typical fish oil doses range from 300 to 1,000 mg per day. You can find fish oil supplements at Care/of.

SHOP NOW AT CARE/OF

Glucosamine is natural component of cartilage, a substance that prevents bones from rubbing against each other and causing pain and inflammation. It might also help prevent the cartilage breakdown that can happen with arthritis.

Many supplements aimed at treating joint pain contain glucosamine, which is one of the most well-studied supplements for osteoarthritis. But despite this research, there are still some questions about how well it works.

There are two types of glucosamine found in supplements: glucosamine hydrochloride and glucosamine sulfate.

One meta-analysis found that products containing glucosamine hydrochloride don’t do much to improve joint pain caused by osteoarthritis. Another study shows that glucosamine sulfate does improve these symptoms, so it may be a better option that glucosamine hydrochloride.

When taken over a long period of time, glucosamine sulfate may also help to slow down the progression of osteoarthritis. Studies suggest that it slows down narrowing of the joint space, a marker of the condition getting worse, when taken for up to three years.

Try it: Glucosamine sulfate is typically taken once daily in a dose of 1,500 milligrams (mg). If this upsets your stomach, try spreading it out over three doses of 500 mg each. You can find glucosamine sulfate supplements on Amazon.

SHOP NOW ON AMAZON

Like glucosamine, chondroitin is a building block of cartilage. It may also help prevent cartilage breakdown from osteoarthritis.

Many clinical studies have found that chondroitin can reduce joint pain and stiffness in people with osteoarthritis. About 53 percent of people who take chondroitin have a 20 percent or greater improvement in knee pain.

Chondroitin sulfate may also slow down the progression of osteoarthritis when taken long-term. Studies show that it slows down narrowing of the joint space when taken for up to 2 years.

Joint supplements often combine chondroitin with glucosamine. But it’s still unclear if taking a combination supplement is any better than taking one or the other on their own.

Try it: Chondroitin is typically taken in a dose of 400 to 800 mg two or three times per day. You can find chondroitin supplements on Amazon.

SHOP NOW ON AMAZON

S-adenosyl-L-methionine (SAMe) is a supplement commonly used to help with symptoms of depression and osteoarthritis. Your liver naturally produces SAMe from an amino acid called methionine. It has several functions, including helping the production and repair of cartilage.

When taken as a supplement, SAMe can help with symptoms of joint pain caused by osteoarthritis. It may be as effective as the anti-inflammatory drug celecoxib (Celebrex). In one study from 2004, celecoxib improved symptoms more than SAMe after a month of treatment. But by the second month, the treatments were comparable.

Try it: SAMe is usually taken in doses of 200 to 400 mg three times per day. Keep in mind that it may take some time to notice results. You can find SAMe supplements on Amazon.

SHOP NOW ON AMAZON

Boswellia, also known as Indian frankincense, is commonly used for pain caused by arthritis. Chemicals in this extract called boswellia acids have anti-inflammatory effects.

Clinical studies have shown that boswellia extracts improve pain symptoms more than a placebo in people with osteoarthritis.

Try it: Studies looking at the use of boswellia for joint pain have used doses ranging from 100 mg once per day to 333 mg three times per day. You can find boswellia supplements on Amazon.

SHOP NOW ON AMAZON

Avocado-soybean unsaponifiables (ASUs) refer to a type of extract from avocado and soybean oils that might help prevent the breakdown of cartilage. It may also help to repair cartilage.

Clinical studies show that ASUs improve pain symptoms more than placebo in people with osteoarthritis.

Try it: The typical dose of ASU is 300 mg per day. You can find ASU supplements on Amazon.

SHOP NOW ON AMAZON

Devil’s claw, also called harpagophytum, contains a chemical called harpogoside that has anti-inflammatory effects.

Taking devil’s claw may help with joint pain from osteoarthritis. In one study, devil’s claw worked about as well as an anti-inflammatory drug called diacerein. However, since there isn’t much research on this supplement for osteoarthritis, more high-quality studies are necessary.

Try it: Most studies involving devil’s claw have used doses of 600 to 800 mg three times per day. You can find devil’s claw supplements on Amazon.

SHOP NOW ON AMAZON

Methylsulfonylmethane (MSM) is another common ingredient in supplements said to help with joint pain.

In one study, MSM improved pain and functioning compared to a placebo in people with osteoarthritis.

Try it: Typical MSM doses range from 1,500 to 6,000 mg per day, sometimes divided into two doses. You can find MSM supplements on Amazon.

SHOP NOW ON AMAZON

Choosing a supplement for joint pain can be overwhelming with the number of products available. Many of these products contain multiple ingredients. Keep in mind that a long ingredient list doesn’t always make for a better product. Also, these products are not regulated by the U.S. Food and Drug Administration so read labels carefully.

In some cases, added ingredients don’t have any proven benefits for joint health. Others might contain multiple beneficial ingredients, such glucosamine and chondroitin. But there’s not much proof that taking supplements containing multiple ingredients is more effective than taking a single ingredient. Plus, some of these products have too little of one or more ingredients for them to be beneficial.

Before choosing a supplement, talk with your doctor or pharmacist about other medications you’re taking so they can check for potential interactions. Some joint health supplements can interact with certain medications, such as blood thinners.

Sports nutrition for joints and ligaments from Fit Health

The most important in the motor and physical activity of a person are connective tissues that provide comfort during movement. These tissues include cartilage, joints, and ligaments.

By themselves, they are a rather fragile structure (for example, a meniscus or a shoulder joint), and their healing is usually painful and never complete: probably everyone has heard the phrase “old injuries come back.” Therefore, it is very important to train in such a way as not only to keep them healthy, but also to strengthen them if possible.

Why do joint and ligament injuries occur?

Basically, all connective tissue injuries occur due to:

• Insufficient warm-up . Taking a lot of weight with insufficiently warmed muscles, there is a high risk of injury.
• Incorrect technique for performing exercise . If performed incorrectly, the entire load falls not on the muscles, but on the ligaments and tendons, thereby contributing to the occurrence of injury.
• Wrong diet . Ligaments and joints consist of connective tissue, which, in turn, consists of collagen – protein filaments, so improper nutrition contributes to its degradation.

A cartilage or joint injury will make you, if not completely put off playing sports, then significantly slow down your progress. Therefore, the main way to maintain the health of your joints and ligaments is timely prevention.

Risk group

Obviously, when playing sports, athletes are required to pay enough attention to the joints and ligaments. But often, in pursuit of mass or strength indicators, athletes use methods to quickly increase weights: as a result, muscles adapted to loads cope with their task, they grow, but our ligaments, not adapted by nature to such loads, are often injured.

At risk are all other athletes whose movements are directly related to a large load on the joints. These are not only power sports (powerlifting, athletics, bodybuilding), but also running, football, jumping rope, martial arts: representatives of these sports are most prone to injury.

Prevention of injuries of the joints and ligaments implies a thorough warm-up before training, as well as eating substances that are useful for the joints and ligaments and various special sports nutrition complexes.

Three Essential Substances for Healthy Joints and Ligaments

The main substance that you should pay close attention to products containing is glucosamine . Glucosamine-rich products have proven to be some of the most effective on the market.

Glucosamine is produced by cartilage in the joints and is the main building block of cartilage, ligaments and joints. It makes them more durable, flexible and resistant to stretching. It is also part of the joint fluid, tendons, bones, skin, nails, hair, muscles and blood vessels.

The effectiveness of glucosamine has been proven by hundreds of studies and the experience of the greatest bodybuilders. It has been proven that taking glucosamine affects the metabolism of cartilage tissue, preventing its degradation. In our store you will find individual glucosamine products such as Glucosamine Sulfate by Ultimate Nutrition or Glucosamine Sulfate by Universal Nutrition.

However, the most popular are products that combine glucosamine with chondroitin. Chondroitin is part of the synovial fluid, and when taken additionally, it will provide improved gliding of the articular surfaces. By itself, chondroitin improves the nutrition of cartilage, significantly reduces pain during inflammation, increases the strength and flexibility of the joints. Taking chondroitin is extremely important in creating new cartilage tissue. A large amount of chondroitin is found in shark cartilage. Our store has a supplement of this natural source of chondroitin – Shark Cartilage from Scitec Nutrition.

The duo of chondroitin and glucosamine is the most popular in this group of drugs. It is in the line of all leading brands: Glucosamine Plus CSA from Optimum Nutrition, Glucosamine-Chondroitin (Joint Support) from Power System, Glucosamine + Chondroitin from Weider, etc.

Another essential supplement to include in your diet if you want to help your joints is Collagen . Collagen is the most common type of protein in our body, it is found in all tissues, in fact it is the main structural protein that binds cells together.

Many athletes supplement their diets with highly absorbable hydrolyzed collagen, such as Scitec Nutrition’s Collagen Liquid (fortified with vitamin B6 and amino acids) or Olimp’s Kolagen Activ Plus (also contains vitamin B6 plus calcium and vitamin C).

Other beneficial nutrients

A number of active and nutrient substances are known, the intake of which will have a beneficial effect on the health of your ligamentous apparatus. They may contain various complex additives, so look in the composition:

• Fatty acids (especially Omega 3). They have a positive effect on the entire body, but they produce a significant healing effect on the joints and ligaments. Scientists have proven that the use of fatty acids helps to significantly reduce pain in the joints, as well as improve their mobility and flexibility.
• Methylsulfonylmethane (or MSM). It has anti-inflammatory and analgesic properties, which is sometimes simply necessary in the treatment of joints. But note that it does not restore the connective tissue itself, so it is almost always found in combination with the above components.
• Vitamins C and E . Vitamin C is involved in the synthesis of collagen – without vitamin C, collagen is not synthesized by the body! Vitamin E helps joints maintain elasticity and flexibility. In addition, these vitamins are antioxidants and reduce oxidative processes in the body. Clinical studies have proven the effectiveness of these vitamins in reducing joint pain after exercise.
• Calcium and vitamin D . Calcium strengthens bones, but for better absorption, it should be taken in combination with vitamin D. Scientists have found that a lack of vitamin D leads to inflammation of the ligaments and joints.

To relieve pain symptoms and provide prompt assistance in case of injuries, you can use Ice Power gels and sprays, which will quickly anesthetize and relieve inflammation. But this measure should be used only in addition to the immediate restoration of cartilage and joints “from the inside” (glucosamine, chondroitin, collagen are required, and, better, serious complexes like Animal Flex from Universal Nutrition).

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What dietary supplements and vitamins are good for joints?

Some diseases that affect the joints are unfortunately almost impossible to prevent, but in some cases, maintaining the health of cartilage tissue – a kind of natural shock absorber that ensures the mobility and normal functioning of the joints – can significantly delay the time when they need help.

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Vitamins and dietary supplements

joints

jcomp / Freepik

What enters our body always affects the most important aspects: movement, breathing, blood circulation. The joints will let you know if there is an excess or lack of important substances inside us.

Contents of the article

Do not self-medicate! In our articles, we collect the latest scientific data and the opinions of authoritative health experts. But remember: only a doctor can diagnose and prescribe treatment.

Why do my joints hurt?

Diseases affecting the joints can be divided into four groups: inflammatory and infectious diseases (these include arthritis, as well as gout, ankylosing spondylitis, Goff’s disease and others), degenerative lesions (they are most often encountered by older people, also to this a group of diseases includes osteoporosis), congenital pathologies, as well as diseases of periarticular tissues – ligaments, tendons, articular capsules and fascia.

What can you do to protect your joints?

What can you do right now to keep your joints healthy? As with most other diseases, it is lifestyle that remains the decisive factor in prevention. Here are a few simple habits that you should develop as early as possible – so that you either didn’t have to go to the doctor at all, or had to do it as late as possible.

Watch your weight

Every four extra pounds of weight puts an extra load on your knees equal to 12 kilos. And with each extra extra kilo, the force that destroys our joints only grows. Unfortunately, excess weight is one of the most common and important factors on which the condition of our joints depends, and, oddly enough, visceral fat is of the greatest importance. The larger your waist, the more dangerous your joints are.

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Switch to a Mediterranean diet

Unfortunately, there is no scientifically proven evidence that any superfoods can help in the fight against joint inflammation. But doctors still advise striving to ensure that your daily diet is as close as possible to the Mediterranean in its composition. If only because this diet is the most effective way to maintain a healthy weight.

Drink more

Cartilage is 80% water, which allows cartilage to move, compress and expand, thereby cushioning the joints. If we drink enough water, we thereby maintain the normal condition of cartilage and prolong their lifespan.

Exercise

Exercises that place little stress on your joints—swimming, walking, cycling, bodyweight exercises—not only help maintain a healthy weight, but also stimulate cartilage production. Moderate exercise forces the body to produce an additional “portion” of cartilage and thereby protect the joints.

Do vitamins and supplements help in joint recovery?

Most often, when problems with the joints begin, doctors prescribe painkillers and anti-inflammatory drugs. However, there are also many supplements on the market that claim their product can help relieve pain and inflammation, as well as protect joints from damage. Is it so?
Clinical studies rather agree that some supplements may be effective in preventing and treating joint disease. So, a review of studies published in 2000 confirmed that the use of chondroitin and glucosamine really helps to reduce inflammation and relieve pain.

Which supplements should I choose to protect my joints?

Glucosamine Sulfate

It is from this substance that cartilage tissue mainly consists, the additional intake of supplements, which include glucosamine, helps to improve the condition of the joints. Thus, a 2009 study confirmed that daily intake of dietary supplements, which include glucosamine sulfate, reduces the pain of osteoarthritis and even helps slow the progression of the disease.

Chondroitin

Another natural component of cartilage that is literally “washed out” of our joints under the influence of disease or simply with age. A 2015 study confirmed that taking this drug helped reduce knee pain by up to 20%. But an important note: you should not take these two supplements together: when taken at the same time, they can even aggravate joint pain. At least the results of a study conducted by specialists from Spain confirm this.

Omega-3

Omega fatty acids and especially Omega-3 fatty acids have a pronounced anti-inflammatory effect, and therefore can be very useful for joint pain. A review of studies published in 2016 confirmed that daily supplementation with Obega-3 was so effective in reducing pain and joint discomfort in rheumatoid arthritis that some of the study participants even refused pain medication.

Gamma-linolenic acid (GLA)

The main component of GLA is omega-6 fatty acids, which, like their “colleagues” omega-3, perfectly cope with inflammatory processes. In addition, taking gamma-linolenic acid helps to reduce pain and stiffness: according to a review of studies published in 2017, taking this supplement daily for six months significantly reduces pain and swelling in the joint area.

Methylsulfonylmethane

This compound contains sulfur, an essential element used to strengthen joints and bones and fight inflammation. But, despite the fact that the effectiveness of taking methylsulfonylmethane for reducing pain and inflammation in arthritis has been confirmed by studies, it should be taken with caution: there is still too little data on the long-term consequences of regularly taking this compound. In addition, there is evidence that taking methylsulfonylmethane can lead to the development of diarrhea, abdominal pain and headache.

Ginger

Gingerol, a compound found in ginger root, has analgesic properties. Some studies confirm that its effect can be as strong as the effect of some painkillers, such as ibuprofen. This spicy root contains the anti-inflammatory compound gingerol, which has pain-relieving properties that can be as strong as over-the-counter drugs like ibuprofen.

Capsaicin

It is this compound that makes the pepper so hot. But it has another useful property – it reduces the body’s pain response and helps relieve chronic pain. But it is important to remember that its action is precisely symptomatic, relieving pain. Copsicin itself does not cure inflammation.

Turmeric

The main component of this bright spice is the chemical compound curcumin, which has analgesic and anti-inflammatory effects. For example, a 2016 study confirmed that regular intake of curcumin helps reduce pain in the knee joints and also supports their functioning.

Tamarind Seed Extract

To increase the effectiveness of Curcumin, take it with Tamarind Seed Extract. By itself, it has anti-inflammatory and anti-stress effects, however, in combination with curcumin, it significantly relieves pain in the knee joints, especially after physical exertion.

Vitamin E

Vitamin E is especially recommended for people suffering from osteoarthritis: this antioxidant, which also has a pronounced anti-inflammatory effect, not only helps to relieve symptoms, but also slows down the progression of the disease. By acting as an antioxidant and anti-inflammatory agent, vitamin E may combat joint pain caused by osteoarthritis and may slow the progression of the disease.