Bisacodyl: a laxative taken to treat constipation

1. About bisacodyl

Bisacodyl is a laxative. This type of medicine can help you empty your bowels if you have constipation (difficulty pooing).

Bisacodyl is also used in hospitals to help you empty your bowels before surgery or some examinations or treatments. Your hospital will explain how to use it.

Bisacodyl comes as a tablet and a suppository (a medicine that you push gently into your anus).

The tablets and suppositories are available on prescription. Small packs are available to buy from supermarkets (up to 20 tablets).

Before trying bisacodyl, it’s better to try other ways to help your constipation by:

• having more fibre in your diet and drinking more water
• exercising

Only use bisacodyl if you have tried other types of laxatives first such as:

• bulk-forming laxatives like Fybogel (ispaghula husk) and methylcellulose
• osmotic laxatives like lactulose and polyethylene glycol

2.

Key facts

• Bisacodyl is known as a stimulant laxative. It relieves constipation by helping your bowel move so you can poo more easily. It also softens your poo.
• Bisacodyl tablets take 6 to 12 hours to work. The suppositories take 10 to 45 minutes to work, so it’s best to stay close to a toilet after you’ve used them.
• The most common side effects are feeling sick (nausea), diarrhoea, stomach pain or cramps.
• Only give bisacodyl to children and young people if a doctor or pharmacist recommends it.
• Do not take bisacodyl tablets or use bisacodyl suppositories every day for more than 5 days.

3. Who can and cannot take bisacodyl

Bisacodyl can be used by most adults aged 18 years and over.

Young people aged 12 to 17 years can take bisacodyl tablets and use suppositories if a doctor or pharmacist says it’s OK.

Children aged 11 years and under can only take and use bisacodyl if a doctor prescribes it.

Important

Only give bisacodyl to someone under the age of 18 if a doctor or pharmacist recommends it.

Bisacodyl is not suitable for some people. To make sure it’s safe for you, tell your doctor or pharmacist if you have:

• ever had an allergic reaction to bisacodyl or any other medicine
• signs of dehydration – these include peeing less than usual or having dark, strong-smelling pee
• severe stomach pain and you are feeling or being sick (nausea or vomiting)
• a serious problem in your stomach (abdomen) such as appendicitis
• a blockage in your bowel (intestinal obstruction), ulcerative colitis or Crohn’s disease
• a problem with the muscles in your bowel not being able to move food and liquid along

For suppositories, also tell your doctor or pharmacist if you have:

• ever had an allergic reaction to suppositories
• tears or open sores (anal fissures) or cracked skin around your anus

4.

How and when to take or use bisacodyl

Always follow the advice of a pharmacist or doctor, and the instructions that come with your medicine.

Dosage for tablets

Bisacodyl tablets you buy (self-treatment)

The usual dose for adults and young people aged 12 years and over is 5mg to 10mg, taken once a day at bedtime.

If you have not taken bisacodyl before, start with one 5mg tablet and if that does not work you can increase the dose to a maximum of two 5mg tablets (10mg) at bedtime.

Important:
Information for ages 12 to 17

Only give bisacodyl tablets that you buy to someone aged 12 to 17 years if a doctor or pharmacist recommends it.

Bisacodyl tablets prescribed by a doctor

The usual starting dose for adults, and children aged 4 years and over, is 5mg, taken once a day at bedtime. A doctor may prescribe higher doses (up to a maximum of 20mg, taken once a day) if necessary.

Dosage for suppositories

The usual dose for:

• adults – one 10mg suppository, used once a day in the morning
• children aged 2 to 17 years – one 5mg or 10mg suppository, used once a day in the morning (on doctor’s advice only)

How to take tablets

Take the medicine once a day just before bedtime.

You can take it with or without food. Swallow the tablet whole with water. Do not take them with milk.

Do not take bisacodyl tablets at the same time as:

• dairy products like milk, cheese or yoghurt
• indigestion remedies (antacids)
• medicines to reduce stomach acid (like proton pump inhibitors such as omeprazole or pantoprazole)

Leave a gap of 1 hour between taking any of these and taking your bisacodyl tablets. This is because they will stop the medicine working properly.

How to use suppositories

Read the instructions in the leaflet inside the package. They will explain how to use the suppository.

Take the wrapping off and push a suppository gently into your anus (bottom).

Suppositories work quickly (usually between 10 and 45 minutes), so use it when you know you will be near a toilet.

What if I forget to take it?

If you forget a dose of bisacodyl, just take the next dose at the usual time.

Never take 2 doses at the same time. Never take an extra dose to make up for a forgotten one.

What if I take too much?

Taking an extra dose of bisacodyl is unlikely to harm you. You may get diarrhoea and stomach pain, but this should get better within a day or two.

If you’re worried, talk to your doctor or pharmacist for advice.

5. Side effects

Like all medicines, bisacodyl may cause side effects in some people, but many people have no side effects or only minor ones.

Common side effects

Common side effects, which happen in more than 1 in 100 people, are:

• feeling sick (nausea)
• diarrhoea
• stomach pain or cramps

These side effects are mild and usually go away after a couple of days. Talk to your doctor or pharmacist if the side effects bother you or do not go away.

Serious side effects

Call your doctor straight away if these rare side effects happen to you:

• feeling dizzy
• blood in your poo
• being sick (vomiting)

Serious allergic reaction

In rare cases, it’s possible to have a serious allergic reaction (anaphylaxis) to bisacodyl.

Immediate action required: Call 999 or go to A&E now if:

• you get a skin rash that may include itchy, red, swollen, blistered or peeling skin
• you’re wheezing
• you get tightness in the chest or throat
• you have trouble breathing or talking
• your mouth, face, lips, tongue or throat start swelling

You could be having a serious allergic reaction and may need immediate treatment in hospital.

These are not all the side effects of bisacodyl. For a full list, see the leaflet inside your medicines packet.

Information:

You can report any suspected side effect using the Yellow Card safety scheme.

Visit Yellow Card for further information.

6. How to cope with side effects of bisacodyl

What to do about:

• feeling sick – try taking bisacodyl with some food. It may also help if you avoid rich or spicy food.
• diarrhoea – stop taking bisacodyl and drink plenty of water or other fluids. Speak to a pharmacist if you have signs of dehydration, such as peeing less than usual or having dark, strong-smelling pee. Do not take any other medicines to treat diarrhoea without speaking to a pharmacist or doctor.
• stomach pain or cramps – reduce your dose of bisacodyl or stop taking it until these side effects go away.

7. Pregnancy and breastfeeding

Bisacodyl and pregnancy

Bisacodyl tablets or suppositories are not generally recommended if you are pregnant. Talk to your doctor about whether taking bisacodyl is right for you.

If you are pregnant, it’s better to try to treat constipation first without taking a medicine. Your doctor or midwife will advise you to eat more fibre and drink plenty of fluids. It may also help to increase your level of exercise if you can.

If diet and lifestyle changes do not work, your doctor or midwife may recommend other laxatives, such as lactulose or Fybogel. These are more suitable to take during pregnancy and while breastfeeding.

Bisacodyl and breastfeeding

If your doctor or midwife recommends bisacodyl, rather than lactulose or Fybogel, it’s OK to use it while you’re breastfeeding. It does not seem to pass into breast milk and is very unlikely to affect your baby.

As with any medicine, if you notice that your baby is not feeding as well as usual, or if you have any other concerns about your baby, talk to your health visitor, midwife or doctor as soon as possible.

Non-urgent advice: Tell your doctor if you’re:

• trying to get pregnant
• pregnant
• breastfeeding

For more information about how bisacodyl can affect you and your baby during pregnancy, read this leaflet on the Best Use of Medicines in Pregnancy (BUMPS) website.

8. Cautions with other medicines

Some medicines, and some foods, affect the way bisacodyl works.

They include:

• medicines that make you pee more (diuretics), steroids (like prednisolone) or digoxin (a heart medicine) – these can upset the balance of salts and minerals in your body if you have too much bisacodyl. If you are taking digoxin, this imbalance makes it more likely you will have the serious side effects of digoxin. Talk to a doctor or pharmacist before taking bisacodyl if you are taking any of these medicines.
• indigestion remedies (antacids) – these stop bisacodyl tablets working properly. They can also make the bisacodyl irritate your stomach and give you indigestion. Do not take bisacodyl at the same time. Leave a gap of 1 hour before or after taking bisacodyl if you are having indigestion remedies.

Mixing bisacodyl with herbal remedies or supplements

There is not enough research to know if complementary medicines and herbal remedies are safe to take with bisacodyl. They are not tested in the same way as other medicines.

Important:
Medicine safety

Tell your doctor or pharmacist if you’re taking any other medicines, including herbal medicines, vitamins or supplements.

9. Common questions about bisacodyl

How does bisacodyl work?

Bisacodyl is known as a stimulant laxative. It relieves constipation by helping your bowel move so you can poo more easily. It also softens your poo.

When will I feel better?

Bisacodyl tablets usually work within 6 to 12 hours after taking them.

The suppositories can take 10 to 45 minutes, so it’s best to stay close to a toilet.

How long will I take bisacodyl for?

Do not take bisacodyl every day for more than 5 days.

If you take bisacodyl for longer, your body can start to rely on it, rather than your bowels doing the work on their own.

If you are still constipated after 5 days, talk to your doctor.

Is it safe to take bisacodyl for a long time?

It’s best to only use bisacodyl occasionally and for a few days at a time.

Using laxatives like bisacodyl for longer than this can lead to diarrhoea.

It can also cause an electrolyte (or salt) imbalance, where levels sodium, potassium and magnesium in your body get too high or too low. A severe electrolyte imbalance can cause serious health problems such as muscle spasm and twitching, and even convulsions.

Using bisacodyl for many weeks, even months, could also stop your bowel working properly on its own.

If you need to use laxatives every day for longer than 5 days, talk to your doctor.

Can I take different laxatives together?

For most people, 1 laxative will be enough to make your constipation better.

Occasionally, you may need to take 2 different types of laxatives at the same time to get your bowels moving again. Only take 2 laxatives together if your doctor or pharmacist tells you to, as this increases the risk of side effects.

Are other laxatives any better?

There are several types of laxative. They work in a different way from bisacodyl but are equally good at treating constipation.

Bulk-forming laxatives, such as Fybogel and methylcellulose, increase the “bulk” or weight of poo, which in turn stimulates bowel movement. They take 2 or 3 days to work.

Osmotic laxatives, such as lactulose, draw water from the rest of the body into your bowel to soften your poo and make it easier for you to go to the toilet. They take at least 2 days to work.

Stimulant laxatives, like senna, stimulate the muscles that line your gut, helping them to move poo along your gut to your anus (bottom). Senna takes about 8 hours to work.

Will it affect my fertility?

There’s no evidence to suggest that taking bisacodyl will reduce fertility in either men or women.

Will it affect my contraception?

Bisacodyl does not affect any type of contraception including the combined pill and emergency contraception.

But if you have severe diarrhoea for more than 24 hours, your contraceptive pills may not protect you from pregnancy. Look on the pill packet to find out what to do.

Find out what to do if you’re on the pill and have diarrhoea.

Is there any food and drink I need to avoid?

Do not take bisacodyl at the same time as dairy products like milk, cheese or yoghurt. Leave a gap of 1 hour between taking any of these and taking your bisacodyl tablets. The small amount of milk in coffee and tea will not affect your bisacodyl tablets.

If you’re constipated it’s a good idea to stop eating pastries, cakes, puddings and cheese for a while, as foods high in fat can make constipation worse.

Can I drink alcohol with it?

Yes, you can drink alcohol with bisacodyl.

Can I use bisacodyl after surgery?

It’s quite common to have constipation after surgery. Using a laxative may help.

If you have constipation after an operation, it’s better to use lactulose because it is gentler than bisacodyl. You can get it on prescription or buy it from pharmacies.

Can lifestyle changes help with constipation?

You can often improve constipation without having to use laxatives. Before trying bisacodyl, or to stop your constipation coming back, it may help to:

• eat more fibre – aim for about 30g of fibre a day. High-fibre foods include fruit, vegetables and cereals. If you’re not used to a high-fibre diet, increase the amount of fibre you eat gradually
• add bulking agents, such as wheat bran, to your diet. These will help make your poo softer and easier to pass (although bran and fibre can sometimes make bloating worse)
• drink plenty of water – this helps to keep poo soft
• exercise regularly – keeping your body active will help to keep your gut moving
• go to the toilet when you need to, rather than holding it in

Adult Suppositories Rectal: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Uses

This product is used to relieve occasional constipation. Glycerin belongs to a class of drugs known as hyperosmotic laxatives. It works by drawing water into the intestines. This effect usually results in a bowel movement within 15 to 60 minutes.For adults, the normal frequency of bowel movements varies from once daily to 1 to 2 times weekly. For preschool-aged children, the normal frequency of bowel movements varies from once daily to once every other day. Constipation is best treated by drinking plenty of fluids, eating foods high in fiber, and exercising regularly.

How to use Adult Suppositories Suppository

This product is for rectal use only. Read and follow all directions on the product package, or use as directed by your doctor. If you have any questions, ask your doctor or pharmacist. If the suppository is too soft to insert, chill in the refrigerator for 30 minutes or run cold water over it before removing the foil wrapper.

Wash your hands before and after using this product. If the medication is wrapped in foil, remove the foil wrapper. If desired, the suppository may be moistened with lukewarm water. Do not use petroleum jelly or mineral oil. Doing so may cause the product to be less effective.

Lie on your left side with the right knee slightly bent. Using your finger, gently insert the suppository well up into the rectum, pointed end first. After insertion, stay in position for 15 to 20 minutes if possible until you feel a strong urge to have a bowel movement. This product does not need to melt completely to produce an effect. If you are helping a child use this product, have the child lie on their side with the lower leg straightened out and the upper leg bent toward the stomach. Using your finger, gently insert the suppository into the rectum, pointed end first. Hold the buttocks together for a few seconds. Then, have your child stay lying down for 15 to 20 minutes if possible to keep the suppository from coming out.

Do not use this product more than once daily unless otherwise directed by your doctor.

If this product is used too frequently, it may cause loss of normal bowel function and an inability to have a bowel movement without using the product (laxative dependence). If you notice symptoms of overuse, such as diarrhea, abdominal pain, decreased weight, or weakness, contact your doctor promptly.

Consult your doctor promptly if you do not have a bowel movement after using this product or if you think you may have a serious medical problem.

Side Effects

Rectal irritation/burning, abdominal discomfort/cramps, or small amounts of mucus in the stool may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

If your doctor has directed you to use this product, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this product do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: abdominal pain that is severe or doesn’t go away, bloody stools, rectal bleeding.

Diarrhea that doesn’t stop may result in dehydration. Contact your doctor promptly if you notice any symptoms of dehydration, such as unusual decreased urination, unusual dry mouth/thirst, fast heartbeat, or dizziness/lightheadedness.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before using glycerin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: rectal bleeding, intestinal blockage (obstruction), other bowel problems (such as ulcerative colitis, hemorrhoids), current stomach/abdominal symptoms (such as nausea/vomiting that doesn’t stop, pain, cramping).

Consult your doctor before using this product if you have had a sudden change in bowel habits lasting more than 2 weeks or if you need to use a laxative for more than 1 week. These could be symptoms of a serious medical problem.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Does Adult Suppositories Suppository interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Keep all medical and lab appointments.

Not applicable.

Refer to storage information on the package label. Protect from high heat. Do not store in the bathroom. If you have any questions about storage, ask your pharmacist. Keep all drug products away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Instructions, after how long they work, dosage, composition

Date of publication: 06.10.2022 POSSIBLE SIDE EFFECTS. A SPECIALIST’S CONSULTATION IS NECESSARY. Antipyretic for adults Antipyretic for children Antipyretic candles s

Article content

• Cefecon: composition
• Cefecon: active substance
• Cefecon suppositories: dosage
• Cefecon: suppositories for newborns
• Cefecon for teething
• Cefecon N: how long does it take to work
• Cefecon D: how long does it take to work
• Summary 9 0016
• Ask an expert about the topic of the article

It is no coincidence that autumn is nicknamed the “season of colds”. The warm summer period is leaving: holidays are ending, the air temperature is dropping, the day is getting shorter, and the workload is increasing. The body is rebuilt to a new mode and becomes vulnerable. It is estimated that annual autumn epidemics of viral diseases lead to 3-5 million cases of severe illness.

Bacteria and viruses attack the weakened immune system, causing a response – fever. It is sometimes difficult to deal with it, especially when it comes to children. Antipyretics come to the rescue, one of which will be discussed in this article.

Pharmacist Kristina Khokhrina will tell you about Cefecon, its composition, dosage, application and how long it takes to start working.

All products Tsefekon

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Tsefekon: composition

There are two types of candles against temperature Tsefekon: Tsefekon N and Tsefekon D (for children). Cefecon H is a combination drug containing caffeine, naproxen and salicylamide. It is used to treat and prevent fever in adults and children over 16 years of age. Cefecon D is paracetamol. It is used in children from 3 months to 12 years.

Cefecon: active ingredient

Both drugs have antipyretic, analgesic and anti-inflammatory effects, but this is achieved through different active ingredients. Cefecon N contains:

• Caffeine is a psychoactive component to eliminate drowsiness and fatigue, as well as increase physical and mental activity.
• Naproxen and salicylamide are anti-inflammatory ingredients that normalize body temperature and relieve pain.

Cefecon for Children contains paracetamol, a safe and well-tolerated antipyretic agent for children. Paracetamol is included in the list of clinical recommendations for the provision of emergency care for acute fever in children.

Cefecon suppositories: dosage

Cefecon is available in the form of suppositories – rectal suppositories. Note that suppositories are a safer dosage form than, for example, tablets. Suppositories cause fewer side effects because they do not enter the stomach, which means that nausea, vomiting and abdominal discomfort will not threaten patients. For the same reason, the effect of candles comes faster.

To use, it is necessary to remove the suppository from the packaging and insert it deep into the rectum, and then lie down for 30-40 minutes.

Cefecon H is used up to 3 times a day, but not more than 3 days in the fight against fever, and not more than 5 days in case of pain. Produced in a single dosage of 10 pieces per pack.

The dose of Cefecon for children is calculated depending on the weight and age of the child. So, for children from 1 to 3 years old weighing 11-16 kg, use 1 suppository of 100 mg. The interval between applications should be at least 6 hours, and the maximum dose should not exceed 60 mg/kg of the child’s weight. Available in 10 suppositories per pack in three dosages: 50, 100 and 250 mg.

Course duration: 3 days for fever and 5 days for pain. Candles are dispensed without a prescription, but it is still worth consulting with a doctor or pharmacist. The drug has contraindications, and an incorrectly calculated dose will lead to an overdose, the consequences of which will be severe.

Cefekon: suppositories for newborns

Newborns are children from the moment of birth until the 28th day of life. The use of Cefecon D during this period is possible, but only once and as directed by a doctor.

Suppositories are used in case of fever due to vaccinations, which are carried out up to 2 months. It is worth inserting a candle into the empty intestine, after warming it up in your hands.

Cefecon for teething

Teething in children begins at the age of 2 to 7 months and is accompanied not only by pain, but also by fever. In this case, Cefecon D will be an effective remedy that eliminates both violations. Candles will not affect the normal body temperature, so you should not be afraid of its excessive decrease.

Cefecon N: how long does it take to start working

Naproxen and salicylamide in Cefecon N allow you to quickly get rid of pain: the effect occurs within 30 minutes after application and lasts up to 8 hours. The anti-inflammatory effect develops within 1-2 weeks.

Cefecon D: how long does it take to act

The maximum effect of paracetamol in the composition of suppositories is achieved 2-3 hours after administration and lasts up to 6 hours.

Summary

• In autumn, the body adjusts to a new regimen and becomes vulnerable
• Cefekon anti-temperature suppositories are of two types: Cefekon N and Cefekon D (for children)
• Cefecon N contains: caffeine, naproxen and salicylamide
• Children’s Cefecon contains paracetamol
• Cefecon is available in the form of suppositories – rectal suppositories
• Cefecon N is used up to 3 times a day, no more than 3 days in the fight against fever, and no more than 5 days – with pain
• The dose of Cefecon for children is calculated depending on the weight and age of the child
• Cefecon D can be used for newborns, but only once and as prescribed by a doctor
• Cefecon D will be an effective remedy for teething in children
• The action of Cefecon N occurs already 30 minutes after application and lasts up to 8 hours
• The maximum effect of Cefecon D is achieved 2-3 hours after administration and lasts up to 6 hours

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Suppositories in gynecology: types and features of use

For the treatment and prevention of many gynecological diseases, local drugs are often prescribed, for example, suppositories. What is the advantage of such medicines?

“Drugs that are injected into the natural cavities of the body are used in complex therapy for the treatment of adnexitis, oophoritis, cervical erosion, colpitis, vaginitis, with polycystic ovaries, endometriosis, to eliminate violations of the vaginal microflora. In addition, suppositories are actively prescribed before and after various surgical interventions, before childbirth or the installation of intrauterine devices.

What explains such a wide range of applications and doctors’ commitment to this dosage form? The fact is that preparations in the form of suppositories have a number of significant advantages: they quickly dissolve and begin to act in the pathological focus, while not only having a therapeutic effect, but also preventing the further spread of the infection. In addition, with this method of treatment, there are practically no side effects that are possible with oral medication. Prescribing drugs in the form of suppositories is especially important if the patient has a history of disorders in the functioning of the liver, kidneys, gastrointestinal tract, cardiovascular system, ”obstetrician-gynecologist, endocrinologist of the GIMed Family Health Clinic Lidia Sheygas draws attention.

Types of suppositories and their mechanism of action

Suppositories are divided into two large groups: vaginal and rectal. According to the form of the introduction of the candle, there are several types. Vaginal are most often round, oval, and also in the form of a cone. Rectal suppositories are produced mainly in the form of a cone.

The composition always contains a solid base (paraffin, gelatin, glycerin), it is she who creates and holds the shape of the suppository, and the active substance. A feature of these drugs is their ability to maintain a solid consistency in the external environment and quickly turn into a liquid inside the body.

The main therapeutic advantage of suppositories is that they not only locally affect the focus of inflammation, but also have a general healing effect. It is known that the area of ​​the vagina and rectum is supplied with a huge number of blood vessels, so the active medicinal components enter the bloodstream very quickly and actively circulate in the pelvic area, while carrying out not only a local therapeutic effect. Biologically available medicinal substances become within 30-60 minutes.

Such therapy quickly relieves the symptoms of the disease, does not affect the menstrual cycle, secretion of gonadotropic hormones, carbohydrate and lipid metabolism. Candles are administered quickly and painlessly, and the use of this group of medicines is rarely accompanied by allergic reactions.

Command staff

As part of a suppository, the active substance can be both synthetic and natural, and also include antibiotics, antiseptics, antifungal and antiviral components, vitamins, probiotics and other substances that help strengthen local immunity. The appointment depends on the pathogenic agent that caused the gynecological disease (viruses, bacteria, fungi or protozoa).

Most suppositories have a complex mechanism of action and can simultaneously relieve the inflammatory process and affect pathogens.

Antibacterial suppositories. The main active ingredient of such drugs are metronidazole, co-trixomazol, penicillins, macrolides. The use of antibacterial drugs always has its own characteristics. If used incorrectly, such drugs can cause allergic reactions, cause oppression of the normal microflora of the vagina and reduce local protective reserves.

Antifungal suppositories . The most famous drugs are fluconazole, clotrimazole, natamycin. The course of treatment depends on many factors, therefore it is determined individually.

Anti-inflammatory suppositories – the main component is non-steroidal anti-inflammatory drugs – diclofenac, ichthyol or indomethacin. They not only relieve inflammation and swelling, but also anesthetize.

Such drugs, from a biological point of view, inhibit the production of prostaglandins, which are produced in large quantities during the inflammatory process and cause pain.

Suppositories with steroidal anti-inflammatory drugs (prednisolone) are less commonly used in gynecological practice.

The therapeutic course of inflammatory diseases lasts up to ten days.

Antiviral suppositories (protiflazid, interferon alfa-2b) are used in clinical practice for the treatment of genital herpes and human papillomavirus (HPV) as part of complex treatment. The therapeutic course is long, the duration of therapy will be determined by the attending physician.

Hormone-based preparations (estriol) – contribute to the restoration of hormonal balance, the pH level in the vagina, suppress the inflammatory process, strengthen the natural barrier, reduce the risk of relapses. The course of treatment is long, determined individually by the doctor.

Candles with natural ingredients , which include sea buckthorn oil, cocoa, eucalyptus, extracts of medicinal herbs, coniferous trees, are prescribed for pregnant women, during lactation, as well as for older people and children.

Suppository Administration: General Rules

It is recommended to administer suppositories at night, preferably before bedtime. Before using rectal suppositories, it is necessary to empty the intestines. The manipulation is carried out lying on its side, bending the legs at the knees and pressing them to the chest. But vaginal suppositories are injected to the maximum depth while lying on your back. Special applicators that are attached to suppositories greatly facilitate the process. After the introduction, you need to be in a horizontal position for at least twenty minutes. This time is enough to dissolve the candle.

The use of the suppository is contraindicated in case of allergic reactions to the components of the preparation.