How does theophylline and guaifenesin combination work for asthma cough. What are the brand names available for this medication. What are the potential side effects and precautions to consider. How should this medication be properly administered for optimal results.

Understanding Theophylline and Guaifenesin Combination for Asthma

Theophylline and guaifenesin combination is a medication used to treat asthma and other respiratory conditions. This powerful duo works synergistically to alleviate symptoms and improve breathing. Theophylline acts as a bronchodilator, relaxing and opening the airways, while guaifenesin serves as an expectorant, thinning and loosening mucus to make coughing more productive.

The combination of these two active ingredients provides a comprehensive approach to managing asthma cough:

• Theophylline: Relaxes smooth muscles in the airways
• Guaifenesin: Reduces mucus viscosity and facilitates its removal

This dual-action mechanism makes theophylline and guaifenesin an effective treatment option for individuals struggling with persistent asthma cough.

Brand Names and Formulations Available

Theophylline and guaifenesin combination is available under various brand names and formulations. Some common brand names include:

• Elixophyllin-GG
• Theolate
• Theocon
• Theophyl-GG

These medications typically come in oral liquid form, making them easier to administer, especially for children or individuals who have difficulty swallowing pills. The syrup formulation allows for precise dosing and quicker absorption, providing faster relief from asthma cough symptoms.

Concentration and Dosage Forms

The concentration of active ingredients may vary depending on the specific brand and formulation. Generally, the medication is available in the following concentrations:

• Theophylline: 50-80 mg per 5 mL
• Guaifenesin: 30-100 mg per 5 mL

It’s crucial to follow the prescribed dosage and consult with a healthcare professional to determine the most appropriate concentration for individual needs.

How Theophylline Works to Alleviate Asthma Symptoms

Theophylline belongs to a class of medications called methylxanthines. Its primary function in treating asthma is to act as a bronchodilator. But how exactly does it work?

1. Relaxes smooth muscles: Theophylline relaxes the smooth muscles surrounding the airways, allowing them to open wider.
2. Reduces inflammation: It helps decrease inflammation in the airways, which is a key factor in asthma.
3. Improves diaphragm function: Theophylline enhances the contractility of the diaphragm, improving overall respiratory function.
4. Increases mucociliary clearance: It helps improve the clearance of mucus from the airways.

By targeting multiple aspects of asthma pathophysiology, theophylline provides comprehensive relief from symptoms, including persistent cough.

Therapeutic Blood Levels

For optimal effectiveness, theophylline must be maintained at specific blood levels. The therapeutic range is typically between 10-20 mcg/mL. Levels below this range may not provide sufficient relief, while levels above it can lead to toxicity. Regular monitoring of blood theophylline levels is essential for safe and effective treatment.

The Role of Guaifenesin in Managing Asthma Cough

Guaifenesin plays a crucial role in managing the cough associated with asthma. As an expectorant, it works by:

• Increasing the volume of respiratory tract fluids
• Decreasing the viscosity of mucus
• Promoting the expulsion of phlegm

These actions make coughing more productive, helping to clear the airways and improve breathing. But how does guaifenesin achieve these effects?

Guaifenesin stimulates receptors in the gastric and bronchial mucosa, triggering a reflex increase in respiratory tract fluid. This increased fluid helps to hydrate and thin mucus, making it easier to expel through coughing. By facilitating the removal of mucus, guaifenesin helps to reduce irritation in the airways and alleviate persistent cough.

Onset and Duration of Action

Guaifenesin typically starts working within 15-30 minutes of administration. Its effects can last for 3-4 hours, providing extended relief from cough symptoms. This duration of action aligns well with the dosing schedule of most theophylline and guaifenesin combination medications.

Proper Administration and Dosage Guidelines

Administering theophylline and guaifenesin combination correctly is crucial for achieving optimal results. Here are some general guidelines:

• Shake the bottle well before each use
• Use a measuring device provided with the medication for accurate dosing
• Take the medication with or without food, but be consistent
• Space doses evenly throughout the day and night for continuous relief
• Do not exceed the recommended dosage

The specific dosage will depend on factors such as age, weight, and severity of symptoms. A typical adult dosage might be 1-2 teaspoons (5-10 mL) every 4-6 hours, not to exceed 6 doses in 24 hours. However, it’s essential to follow the prescribing physician’s instructions or the package directions carefully.

Dosage Adjustments

Dosage adjustments may be necessary based on individual response to the medication or changes in asthma severity. Factors that might necessitate dosage adjustments include:

• Changes in smoking habits
• Concurrent use of certain medications
• Liver or kidney function changes
• Onset of fever or viral illness

Regular follow-ups with a healthcare provider are important to ensure the dosage remains appropriate and effective.

Potential Side Effects and Precautions

While theophylline and guaifenesin combination can be highly effective in managing asthma cough, it’s important to be aware of potential side effects and take necessary precautions. Common side effects may include:

• Nausea or vomiting
• Stomach upset or discomfort
• Headache
• Insomnia or nervousness
• Increased heart rate

Most side effects are mild and tend to diminish as the body adjusts to the medication. However, if side effects persist or worsen, it’s important to consult a healthcare provider.

Serious Side Effects

In rare cases, more serious side effects may occur. These can include:

• Irregular heartbeat
• Seizures
• Severe allergic reactions
• Signs of theophylline toxicity (e.g., persistent vomiting, confusion, rapid breathing)

If any of these serious side effects occur, immediate medical attention should be sought.

Precautions and Contraindications

Certain individuals may need to exercise caution or avoid using theophylline and guaifenesin combination. These include:

• Pregnant or breastfeeding women
• Individuals with liver or kidney disease
• Those with a history of seizures or heart problems
• People taking certain medications that may interact with theophylline

It’s crucial to provide a complete medical history and list of current medications to the prescribing physician to ensure safe and appropriate use of this medication.

Drug Interactions and Considerations

Theophylline can interact with various medications and substances, potentially affecting its efficacy or increasing the risk of side effects. Some important interactions to be aware of include:

• Certain antibiotics (e.g., erythromycin, ciprofloxacin)
• Cimetidine
• Oral contraceptives
• Allopurinol
• Calcium channel blockers
• Caffeine

These interactions can either increase or decrease theophylline levels in the blood, potentially leading to toxicity or reduced effectiveness. It’s crucial to inform healthcare providers about all medications, supplements, and dietary habits to avoid potential interactions.

Influence of Diet and Lifestyle

Certain dietary and lifestyle factors can also affect theophylline levels:

• High-protein, low-carbohydrate diets may decrease theophylline levels
• Charcoal-broiled foods can increase theophylline clearance
• Smoking can increase theophylline metabolism, requiring higher doses
• Alcohol consumption can alter theophylline levels unpredictably

Maintaining consistency in diet and lifestyle habits can help ensure stable theophylline levels and optimal treatment effectiveness.

Monitoring and Follow-up Care

Regular monitoring is essential when using theophylline and guaifenesin combination for asthma cough. This typically involves:

• Periodic blood tests to check theophylline levels
• Lung function tests to assess treatment effectiveness
• Regular check-ups to evaluate overall asthma control
• Monitoring for potential side effects or complications

The frequency of monitoring may vary depending on individual factors such as age, overall health, and response to treatment. Your healthcare provider will determine the appropriate monitoring schedule.

Self-monitoring Techniques

In addition to professional monitoring, patients can employ self-monitoring techniques to track their asthma symptoms and medication effectiveness:

• Keeping a symptom diary
• Using a peak flow meter to measure lung function at home
• Tracking medication use and any side effects experienced
• Noting any triggers that exacerbate symptoms

These self-monitoring practices can provide valuable insights to healthcare providers, allowing for timely adjustments to the treatment plan if needed.

By understanding the mechanisms, proper usage, potential side effects, and monitoring requirements of theophylline and guaifenesin combination, patients can effectively manage their asthma cough and improve their quality of life. Always consult with a healthcare professional for personalized advice and treatment recommendations.

The Best Cough Syrup for Asthma: A Comprehensive Guide

Living with asthma can be challenging, especially when it comes to managing coughing fits. While there is no cure for asthma, there are many treatments available to help manage symptoms. One of the most common treatments for coughing fits associated with asthma is cough syrup. But with so many options on the market, how do you know which one is the best for you?

Top Cough Syrups for Asthma

When it comes to finding the best cough syrup for asthma, there are a few key ingredients to look for:

• Guaifenesin: This ingredient helps to thin mucus, making it easier to cough up.
• Dextromethorphan: This ingredient helps to suppress coughing.
• Bromhexine: This ingredient helps to break up mucus, making it easier to cough up.

Based on these criteria, here are some of the top cough syrups for asthma:

• Robitussin DM: This cough syrup contains both guaifenesin and dextromethorphan, making it a great option for managing coughing fits associated with asthma.
• Mucinex: This cough syrup contains guaifenesin and is designed to help thin mucus, making it easier to cough up.
• Bisolvon: This cough syrup contains bromhexine and is designed to help break up mucus, making it easier to cough up.

Managing Asthma Symptoms

While cough syrup can be a helpful tool in managing asthma symptoms, it’s important to remember that it is just one part of a larger treatment plan. Here are some other tips for managing asthma symptoms:

• Avoid triggers: Identify and avoid triggers that can cause asthma symptoms, such as smoke, dust, and pollen.
• Take medication as prescribed: Make sure to take any prescribed medication as directed by your doctor.
• Use a peak flow meter: A peak flow meter can help you monitor your breathing and identify when your symptoms are getting worse.

Book an Appointment with Nao Medical

If you’re struggling to manage your asthma symptoms, Nao Medical is here to help. Our pulmonology specialists can work with you to develop a personalized treatment plan that meets your unique needs. Book an appointment today and take the first step towards better asthma management.

Book an Appointment

FAQs

What is asthma?

Asthma is a chronic respiratory condition that causes inflammation and narrowing of the airways, making it difficult to breathe.

What are the symptoms of asthma?

Symptoms of asthma can include coughing, wheezing, shortness of breath, and chest tightness.

What causes asthma?

The exact cause of asthma is unknown, but it is believed to be a combination of genetic and environmental factors.

Can asthma be cured?

There is no cure for asthma, but it can be managed with proper treatment.

What is a peak flow meter?

A peak flow meter is a device used to measure how quickly you can exhale air from your lungs. It can help you monitor your breathing and identify when your asthma symptoms are getting worse.

Disclaimer: The information presented in this article is intended for general informational purposes only and should not be considered, construed or interpreted as legal or professional advice, guidance or opinion.

Asthma Cough | Causes, Symptoms & Treatment

Overview

People with asthma have acute episodes where the air passages in their lungs get narrower, and breathing becomes more difficult. Sometimes episodes of asthma are triggered by allergens, although infection, exercise, cold air and other factors are also important triggers.</span>” rel=”tooltip”>Asthma affects the airways in the lungs, making them inflamed and swollen. The breathing tubes also become reactive, causing them to squeeze and tighten. That, in turn, makes the lungs more likely to be affected by allergens or irritants, such as pollen, pet dander, strong scents or fragrances, stress, exercise or cold air. Coughing is the body’s way of trying to remove whatever is irritating the lungs.

While people with asthma often experience a whistling or wheezing sound in the chest in addition to coughing, there is a form of asthma in which the only symptom is a chronic cough. This is known as cough-variant asthma. People with this kind of asthma generally don’t get relief from over-the-counter cough medicine; successful treatment requires prescription asthma medication, often in the form of inhalers.

Find expert care.

Don’t let allergies or asthma hold you back from the things you love.

What should be done to control an asthma cough?

Prevention is always the best strategy. A person with asthma should know what situations trigger coughing and avoid them whenever possible. If coughing or other asthma symptoms are severe or unpredictable, or if they flare up more than twice a week, seeing an allergist can help determine their cause and provide long-term treatment that controls or eliminates them. Asthma medications prescribed by your allergist will help to relieve the coughing attacks. These include a fast-acting bronchodilator inhaler, which expands the airways in the lungs and offers quick relief, or a corticosteroid inhaler, which relieves It is a characteristic of allergic reactions in the nose, lungs, and skin."}" data-sheets-userformat="{"2":8963,"3":{"1":0},"4":[null,2,16777215],"11":4,"12":0,"16":10}">Inflammation is the redness, swelling, heat and pain in a tissue due to chemical or physical injury, or to infection. It is a characteristic of allergic reactions in the nose, lungs, and skin.</span>” rel=”tooltip”>inflammation when used daily. Often both types are needed.

Common Asthma Cough Triggers

Coughing from asthma can occur after exercise, after exposure to specific triggers, after laughing, and often at night. Common triggers include:

• Outdoor allergens, such as pollens from grass, trees and weeds
• Indoor allergens, such as pet dander, dust mites and mold
• Certain drugs or food additives
• Irritants in the air, such as smoke, air pollution and chemical fumes, or strong odors, such as perfume
• Colds, the flu or other illnesses
• Exercise (although people with asthma benefit from exercise; if asthma prevents you from exercising then you should talk to your doctor)
• Stress
• Weather conditions, such as cold air, heat and humidity, or rapidly changing weather patterns

For more information, visit the Asthma page.

Bronchial asthma: faces, how to prescribe for healing

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Editorial team

Creation date: 04/27/2021
Update date: 06/28/2023

Bronchial asthma – not seriously ill, like going over to a normal breath, so through the inflammation, sputum, the phlegm sounds like dihal paths, which lead to legends.

Global news

Illness begins in the early morning. Approximately 50% of children, with the right treatment, recover from asthma to a mature age.

Causes of asthma culprit

Asthma is blamed through hypersensitivity to subdivisions. Asthma can be associated with both spadkovoy schilnistyu, and s factors of the common middle (including allergic chinniki or part of the infection of the dyhal pathways).

Asthma attack may be called:

• allergens: animal wool, saws, food products, mites, files, spores;
• viral and bacterial infections: bronchitis, colds, flu, sinusitis;
• as imitations for the most common medium: fluff gases, sprays, perfumes, tyutyunovy smoke;
• drug treatments, such as acetylsalicylic acid and non-steroidal antiseptic drugs. If you have “aspirin asthma”, it is necessary to avoid taking acetylsalicylic acid and non-steroidal anti-inflammatory drugs, especially considering those that this type of asthma can be even more important and attacks can be blamed more quickly;
• stresses: praise, fear;
• intense physical pressures, especially in cold areas.

Symptoms

If asthma becomes more severe, the symptoms may vary in different people. Most of the ailments show first symptoms in early age: about half of the patients in children under 10 years of age and close to a third of them up to 40 years of age. Prote, asthma can be blamed on a skin person in any case.

Asthma may cause different degrees of severity and frequency of congestion. Asthma symptoms can be different: slight wheezing, wheezing and cough up the buttocks, chest tightness and attacks of the venom.

When coughing, which is accompanied by whistling breaths or difficult breaths, they turn back to the doctor. Even if the diagnosis is already made, if the sick vinicula needs to take the inhaler more often, then it was prescribed, then go back to your doctor.

If the symptoms increase or do not go away for 24-48 years, you may need emergency medical assistance and hospitalization. If an ailing person begins to have an attack of the breath, language is difficult, then the next negainoly call the shvidka to help.

Complication of asthma

• pneumothorax (repeated hit in the empty pleural space)

• acute dychal insufficiency

• emphysematous lesions of the leg

What can you do

First, for all the next, consult a doctor, take a refresher and take the necessary therapy and recommendations.

It is necessary that a person who suffers from asthma, and his family has provided the maximum amount of information about asthma for accredited and recognized patients.
You are guilty of buti warehousing the plan of likuvannya. It is necessary to know exactly the symptoms of an asthma attack, but mothers should have written instructions with them about those that are necessary to work in an emergency situation. Note all preparations, attacks, indications, reactions to preparations.
It is your fault to know for sure, like faces, if it is necessary to accept it in a certain amount. It is also necessary to know, if there can be side effects, and if so, show them quickly. Carefully follow these instructions. Learn how to use the inhaler correctly. Follow along, so that you always have all the necessary preparations at hand. If you are prescribed new asthma treatments, ask your doctor or pharmacist to review your drug interactions with these drugs, if you are already taking them.

Every day, write down your symptoms in order to reduce the frequency and alleviate asthma attacks.

Find out all possible factors that will pour into your camp and provoke attacks. To help you figure out the factors, your records will help you. As among the factors, the wool of the creatures and the drank, take them in and take them out of your booth. Unique cigarette smoke and exhaust gases.

Before the attack of asthma, finish the folded back to the plan. Stay calm, take a deep breath and wink in the inhaler. As soon as the first symptoms of an attack appear, it is not a good idea to come in. In the early phase, it will take less lykiv and an hour to launch an attack.

Be in good physical shape. You need to control your asthma so that you can play sports.

Change your mind, there are more people in your homeland, but you, who know, need to know the necessary faces, like, in such a quantity and in such a sequence, accept that work in emergency situations.

See a doctor regularly for analysis and evaluation of your condition.

How can you get the drug

Carry out obstenia and selective therapy: bronchodilators in the form of aerosols or inhalers, if necessary, consider steroids in the form of inhalers and/or all radish.
Assign treatment with antibiotics to accompany the infection.

Teach you how to use outhouses (various types of inhalers and pills) to get the best amount of them.

Prophylactic approach for bronchial asthma

Know exactly what factors can provoke an asthma attack. If possible, uniqati tsikh chinnikov. Follow the cleanliness in the booth and sleep, be it allergens: saws, wool of creatures, mites and others. Unique cigarette smoke, exhaust gas and in. Throw a fire, as if you are smoking. Take all the preparations you are recommended to speed up the frequency of attacks. Go in for sports so that you can become a heart and a legend.

Respect! Symptom card is recognized as exclusive for lighting purposes. Do not engage in self-deception; with good food, as if you are suffering from illness and ways of yogo rejoicing, go to the doctor. Our site does not bear any responsibility for the references, caused by the wrong placement on the new information.

Chronic cough: types and treatment

Contents:
Typical causes affecting the types of cough
Treatment of chronic cough
Prevention of chronic cough

Cough is one of the most typical symptoms of various diseases of the respiratory system. This is a protective reaction of the body, aimed at cleansing the respiratory tract from excess sputum, irritating substances or foreign bodies. Most often, it occurs due to irritation of cough receptors – specific nerve formations located in the upper and lower respiratory tract. If such a condition becomes protracted and lasts more than 8 weeks, a chronic cough is diagnosed.

Typical causes affecting types of cough

There are many different causes of chronic cough. The main ones include the following.

Postnasal drip syndrome

Postnasal drip syndrome (drainage of nasal mucus down the back of the throat) stimulates cough receptors and can cause chronic cough with sputum. Often, nasal breathing difficulties and mucus getting into the throat of a child or adult cause the development of pharyngitis. In this case, cough syrup Doctor MOM 9 can be used as a symptomatic treatment.0429 ® , which includes the “FITO BRONHO 10 formula” ¹ based on extracts of 10 medicinal plants or herbal cough lozenges Dr. MOM ^® with the “FITO BRONHO formula” ² . These phyto-drugs, which have an expectorant effect, facilitate the elimination of sputum, and with it the infectious agents.

Active and passive smoking

One of the detrimental effects of smoking is chronic hacking cough. Active smokers most often have a morning cough with viscous sputum that is difficult to separate (the result of a reversible violation of bronchial patency). As for dry or wet chronic cough in a child or adult who is forced to inhale tobacco smoke (the so-called passive smoking), it may develop due to the increased sensitivity of the bronchi.

Atmospheric air pollution

The presence of pollutants in the atmospheric air (in particular, small suspended particles less than 10 microns in size) often causes a protective reaction of the body in the form of a dry or wet cough.

Occupational hazards

Occupational hazards that can cause the development of chronic cough in an adult include exposure to cotton, cereal, industrial dust (so-called dust bronchitis), chemicals dissolved in the air, smoke from burning wood, etc. .

Reflux esophagitis

Gastroesophageal reflux disease (reflux of acidic stomach contents into the esophagus) can also cause a chronic, paroxysmal, wet cough with a small amount of sputum.

Eosinophilic bronchitis and bronchial asthma

Eosinophilic allergic bronchitis and bronchial asthma can develop in both a child and an adult due to increased susceptibility of the bronchi to irritants. Cough in some cases may be the only sign of the disease. At the same time, a decrease in the severity of symptoms of chronic cough against the background of antiallergic treatment is often a confirmation of the diagnosis.

Chronic obstructive pulmonary disease (COPD for short)

COPD is a lung disease that prevents normal breathing. The most common cause of this condition is years of smoking. Also, this pathology, characterized by shortness of breath and the development of a prolonged wet cough with copious amounts of sputum, can develop in an adult due to prolonged inhalation of polluted air or harmful chemical fumes.

ACE inhibitors

One of the side effects of taking angiotensin-converting enzyme inhibitors (drugs often used in the treatment of cardiovascular disease) is a dry, hacking cough. A similar symptom is most often found in women (due to a lower cough threshold). It does not depend on age and bronchial hyperactivity and is not a consequence of smoking. The true cause of the side effect remains unknown to date.

Treatment of chronic cough

How to treat chronic cough in children and adults? To objectively answer this question, it is necessary to find out the cause of this symptom. At the same time, there are generally accepted non-specific methods of treatment, in most cases, allowing to alleviate a dry cough or improve sputum discharge with a wet cough. These include a plentiful warm alkaline drink, steam inhalation and the use of special antitussives.

Symptomatic treatment to relieve expectoration

If chronic bronchitis, tracheitis, pharyngitis or laryngitis has become the cause of constant irritation of the cough receptors, one of the preparations of the Doctor MOM ^® line can be used as an effective remedy. These are complex natural preparations of symptomatic action that allow you to turn a dry, unproductive cough into a wet one and facilitate coughing. They are available in the form of syrup and herbal cough lozenges. Syrup with “formula FITO BRONHO 10” ¹ can be given to children from 3 years of age and adults. Pastilles are for adults only.

Treatment of postnasal drip

In addition to chronic cough, decongestants and antihistamines may be used for postnasal drip. Also, strictly according to medical indications, antibiotic therapy can be prescribed.

Cough control in bronchial asthma and COPD

In the treatment of chronic dry cough caused by bronchial asthma, special drugs are usually recommended that block asthma attacks, as well as drugs that reduce the severity of the inflammatory process. factor and symptomatic drug therapy.

Treatment of cough associated with reflux esophagitis

If reflux esophagitis is the cause of negative symptoms, a special diet and medications are usually prescribed to reduce the acidity of the gastric juice. Since chronic cough with GERD can only be alleviated or cured by such methods, antitussive drugs are not prescribed in this situation.