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The gerson therapy success rate. Gerson Therapy Success Rate: Remarkable 5-Year Survival Rates for Melanoma Patients

What are the five-year survival rates for melanoma patients treated with Gerson diet therapy. How do these rates compare to conventional treatments. What does the Gerson therapy entail. Are there any limitations to this study.

Содержание

Understanding Gerson Therapy and Its Impact on Melanoma Survival Rates

Gerson therapy, a controversial alternative treatment approach, has garnered attention for its potential impact on melanoma survival rates. This retrospective study conducted by G.L. Hildenbrand and colleagues examines the five-year survival rates of melanoma patients treated with Gerson’s diet therapy. The results, published in the journal Alternative Therapies in Health and Medicine, suggest significantly higher survival rates compared to conventional treatments.

What is Gerson Therapy?

Gerson therapy is a dietary approach developed by Dr. Max Gerson in the 1920s. It involves:

  • A lactovegetarian diet
  • Low sodium, fat, and (temporarily) protein intake
  • High potassium, fluid, and nutrient consumption
  • Hourly raw vegetable and fruit juices
  • Increased metabolism through thyroid supplementation
  • Limited calorie supply (2600-3200 calories per day)
  • Coffee enemas as needed for pain relief and appetite stimulation

Analyzing the Study: Methodology and Patient Demographics

The study was conducted retrospectively at a hospital in Tijuana, Mexico. It included 153 white adult patients aged 25-72 years with superficial spreading and nodular melanoma. The main outcome measure was the five-year survival rate, categorized by stage at admission.

How were the patients classified?

Patients were grouped into the following stages:

  1. Stages I and II (localized melanoma)
  2. Stage IIIA (regionally metastasized)
  3. Combined stages IIIA + IIIB (regionally metastasized)
  4. Stage IVA (distant lymph, skin, and subcutaneous tissue metastases)
  5. Stage IVB (visceral metastases)

Impressive Survival Rates: Breaking Down the Results

The study reported remarkable survival rates across various stages of melanoma:

Stages I and II (Localized Melanoma)

For patients with localized melanoma (stages I and II), the results were striking:

  • 100% of the 14 patients treated with Gerson therapy survived for 5 years
  • This compares to a 79% survival rate reported by Balch for 15,798 patients receiving conventional treatments

Stage IIIA (Regionally Metastasized)

The survival rates for stage IIIA melanoma also showed significant improvements:

  • 82% of 17 patients treated with Gerson therapy were alive at 5 years
  • In contrast, only 39% of 103 patients from Fachklinik Hornheide survived using conventional treatments

Combined Stages IIIA + IIIB

When combining stages IIIA and IIIB, the results remained impressive:

  • 70% of 33 patients on Gerson therapy lived for 5 years
  • This is compared to a 41% survival rate for 134 patients from Fachklinik Hornheide

Introducing a New Stage Division: IVA and IVB

The researchers proposed a new stage division for advanced melanoma:

  • Stage IVA: Distant lymph, skin, and subcutaneous tissue metastases
  • Stage IVB: Visceral metastases

For stage IVA melanoma:

  • 39% of 18 patients treated with Gerson therapy were alive at 5 years
  • This is in stark contrast to only 6% of 194 patients from the Eastern Cooperative Oncology Group surviving with conventional treatments

The survival impact for stage IVB was not assessed in this study.

Gender Differences in Survival Rates

An interesting finding emerged when comparing survival rates between males and females:

  • For stages I-IIIB, male and female survival rates were identical
  • However, stage IVA women demonstrated a strong survival advantage over men

This gender disparity in advanced melanoma survival rates warrants further investigation to understand the underlying factors.

Limitations and Considerations of the Study

While the results of this study are intriguing, it’s important to consider several limitations:

  • Retrospective design: The study was not a randomized controlled trial, which is considered the gold standard for medical research
  • Small sample size: With only 153 patients, the study may not be representative of the broader melanoma patient population
  • Single-center study: The research was conducted at one hospital in Tijuana, Mexico, which may limit its generalizability
  • Potential selection bias: Patients who chose Gerson therapy may have had other factors influencing their survival rates
  • Lack of control group: The study compared results to historical data rather than a concurrent control group

Implications for Melanoma Treatment and Future Research

The significantly higher survival rates reported in this study raise important questions about the potential benefits of Gerson therapy for melanoma patients. However, more rigorous research is needed to confirm these findings and understand the mechanisms behind the observed effects.

Areas for further investigation:

  • Randomized controlled trials comparing Gerson therapy to standard treatments
  • Larger, multi-center studies to increase sample size and generalizability
  • Investigation of the specific components of Gerson therapy that may contribute to improved survival
  • Exploration of potential synergies between Gerson therapy and conventional melanoma treatments
  • Long-term follow-up studies to assess the durability of treatment effects

The Controversy Surrounding Gerson Therapy

Despite the promising results reported in this study, Gerson therapy remains a controversial treatment approach in the medical community. Several factors contribute to this controversy:

Why is Gerson therapy controversial?

  • Lack of large-scale, randomized controlled trials
  • Concerns about nutritional deficiencies and electrolyte imbalances
  • Potential risks associated with coffee enemas
  • Skepticism about the biological plausibility of the therapy’s mechanisms
  • Concerns that patients may forgo conventional treatments in favor of Gerson therapy

It’s crucial for patients considering Gerson therapy to discuss the potential risks and benefits with their healthcare providers and to make informed decisions based on the best available evidence.

The Role of Diet and Lifestyle in Cancer Treatment

While the specific benefits of Gerson therapy require further investigation, the study highlights the potential importance of diet and lifestyle factors in cancer treatment and survival. This aligns with a growing body of research examining the impact of nutrition on cancer outcomes.

How might diet influence cancer progression?

  • Modulation of inflammation and oxidative stress
  • Influence on hormone levels and growth factors
  • Impact on the gut microbiome and immune function
  • Potential direct effects on cancer cell metabolism

As research in this area continues to evolve, integrative approaches that combine evidence-based conventional treatments with carefully designed nutritional interventions may hold promise for improving cancer outcomes.

Ethical Considerations in Alternative Cancer Therapies

The study of alternative therapies like Gerson therapy raises important ethical considerations for researchers, healthcare providers, and patients:

What ethical issues surround alternative cancer treatments?

  • Balancing patient autonomy with evidence-based medicine
  • Ensuring informed consent and managing patient expectations
  • Addressing potential conflicts of interest in research and promotion of therapies
  • Allocating research resources between conventional and alternative approaches
  • Integrating promising alternative therapies into mainstream cancer care

As the field of integrative oncology continues to evolve, it’s crucial to maintain a balanced, evidence-based approach while remaining open to potentially beneficial alternative therapies.

The Future of Melanoma Treatment: Integrating Conventional and Alternative Approaches

The results of this study on Gerson therapy, while preliminary, suggest that there may be value in exploring integrative approaches to melanoma treatment. As our understanding of cancer biology and the complex interplay between diet, lifestyle, and disease progression continues to grow, new opportunities for improving patient outcomes may emerge.

What might the future of melanoma treatment look like?

  • Personalized treatment plans combining conventional and evidence-based alternative therapies
  • Greater emphasis on nutrition and lifestyle interventions as adjuncts to standard care
  • Increased research into the mechanisms of action for promising alternative therapies
  • Development of novel therapies inspired by traditional and alternative medicine approaches
  • Enhanced patient education and shared decision-making in treatment selection

While Gerson therapy itself requires further rigorous study, the principles of nutritional support and detoxification that underlie the approach may offer valuable insights for future melanoma treatment strategies.

As research in this field progresses, it’s essential to maintain a critical and evidence-based perspective while remaining open to innovative approaches that may benefit patients. The ultimate goal is to improve survival rates and quality of life for individuals facing melanoma and other forms of cancer.

Five-year survival rates of melanoma patients treated by diet therapy after the manner of Gerson: a retrospective review

Comparative Study

. 1995 Sep;1(4):29-37.

G L Hildenbrand 
1
, L C Hildenbrand, K Bradford, S W Cavin

Affiliations

Affiliation

  • 1 Gerson Research Organization, San Diego, Calif., USA.
  • PMID:

    9359807

Comparative Study

G L Hildenbrand et al.

Altern Ther Health Med.

1995 Sep.

. 1995 Sep;1(4):29-37.

Authors

G L Hildenbrand 
1
, L C Hildenbrand, K Bradford, S W Cavin

Affiliation

  • 1 Gerson Research Organization, San Diego, Calif. , USA.
  • PMID:

    9359807

Abstract


Objective:

Compare 5-year melanoma survival rates to rates in medical literature.


Design:

Retrospective.


Setting:

Hospital in Tijuana, Mexico.


Patients:

White adult patients (N = 153) with superficial spreading and nodular melanoma, aged 25-72 years.


Intervention:

Gerson’s diet therapy: lactovegetarian; low sodium, fat and (temporarily) protein; high potassium, fluid, and nutrients (hourly raw vegetable/fruit juices). Metabolism increased by thyroid; calorie supply limited to 2600-3200 calories per day. Coffee enemas as needed for pain and appetite.


Main outcome measure:

5-year survival rates by stage at admission.


Results:

Of 14 patients with stages I and II (localized) melanoma, 100% survived for 5 years, compared with 79% of 15,798 reported by Balch. Of 17 with stage IIIA (regionally metastasized) melanoma, 82% were alive at 5 years, in contrast to 39% of 103 from Fachklinik Hornheide. Of 33 with combined stages IIIA + IIIB (regionally metastasized) melanoma, 70% lived 5 years, compared with 41% of 134 from Fachklinik Hornheide. We propose a new stage division: IVA (distant lymph, skin, and subcutaneous tissue metastases), and IVB (visceral metastases). Of 18 with stage IVA melanoma, 39% were alive at 5 years, compared with only 6% of 194 from the Eastern Cooperative Oncology Group. Survival impact was not assessed for stage IVB. Male and female survival rates were identical for stages I-IIIB, but stage IVA women had a strong survival advantage.


Conclusions:

The 5-year survival rates reported here are considerably higher than those reported elsewhere. Stage IIIA/B males had exceptionally high survival rates compared with those reported by other centers.

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Publication types

MeSH terms

Gerson therapy | Complementary and alternative therapy

Gerson therapy involves a specific organic vegetarian diet with nutritional supplements and enemas. There is no scientific evidence to use it as a treatment for cancer.

Summary

  • Gerson therapy uses a specific organic vegetarian diet, nutritional supplements and enemas to treat cancer
  • There is no scientific evidence that it can treat cancer or its symptoms
  • Gerson therapy can have severe side effects

What is Gerson therapy?

A German doctor called Max Gerson developed Gerson therapy in the 1920s and 30s. He claimed that it helped cure his migraine headaches. So, he went on to use it to treat other diseases such as tuberculosis and cancer.

You might also hear Gerson therapy called the:

  • Gerson diet
  • Gerson regimen
  • Gerson method

Followers believe that changes to diet and nutrient intake can help to treat cancer. They also think that cancer is a symptom of disease of the whole body. 

It aims to rid the body of toxins and strengthen the body’s immune system. This way supporters say it can bring the body back to its normal metabolic state, and the body can heal itself.

The Gerson regime has 3 main parts:

  • a strict organic vegetarian diet made up of fruit and vegetables high in potassium and low in sodium
  • vitamin and mineral supplements, and specific enzymes
  • coffee or castor oil enemas

Gerson therapists believe that people with cancer have too much salt (sodium) in their bodies. This is compared to the amount of potassium.

People following the therapy only eat organic, vegetarian food. This includes up to 13 glasses of fresh juices a day. It is believed that by doing so, it will restore the right balance. And that it will cleanse the liver. 

Up to 5 coffee enemas a day are also given. It is believed that coffee enemas further help to excrete toxins from the liver and colon. And that taking certain supplements and enzymes help the body to get rid of cancer cells.

Scientific research does not support any of these claims.

Why people with cancer use it

They hope it will control or cure their cancer

Your doctor may have told you that conventional treatments cannot cure your cancer. This can be tough to accept.

In this situation, many people look for alternative therapies, including diets such as Gerson. But there is no scientific evidence that the Gerson diet works. It may cause serious health problems and make you feel worse.

The Gerson Research Organisation published a study in 1995. It looked at people with melanoma skin cancer who were doing the Gerson regime. It found that people on the diet had higher survival rates. This was when compared to rates that were published in other scientific studies.  

But a review study in 2014 found that the 1995 research was not accurate. It also did not use a single classification of tumour staging. Tumour staging means the size of a cancer and how far it has spread. The researchers said that they couldn’t say whether the Gerson regime worked.

Gerson therapy is popular with many people who have advanced cancer. But we need more scientific research before it can be used as a treatment for cancer.

Diet may play an essential role in helping to prevent cancer. But there is no current evidence to say that drastic diet changes will kill cancer cells.

Talk to your doctor before making any decisions about following an alternative diet.

To feel more in control

Some people use alternative or complementary therapy to feel more in control of their cancer and its treatment.

To boost the immune system

Some people believe that Gerson therapy boosts their immune system. By doing so, it helps to fight their cancer.

There is no scientific evidence to prove this, partly because of lack of research. We, need more research to have proof. Only then can we say with certainty that Gerson therapy affects the immune system.

How you have it

The Gerson diet is a strict low salt, organic fruit and vegetable diet.

Each day you will need to:

  • drink 20 pounds (about 9 kilos) of crushed fruit and vegetables (one glass of juice hourly, 13 times each day)
  • have up to 5 coffee enemas and perhaps also castor oil enemas
  • take potassium and other supplements, including vitamin B12, pancreatic enzymes and thyroid supplements

You can have Gerson therapy by staying in a clinic, or you can do it yourself at home.

The Gerson Institute refers people to clinics licensed by them. Their most popular one is in Mexico and there is also one in Hungary.

Gerson therapists advertise their clinics as very safe, relaxing and caring. But it is worth finding out if they have the medical facilities needed if any emergencies arise.

People who go to these clinics sometimes say that they feel better psychologically. These places might be very relaxing and caring places to be. But the possible side effects of Gerson therapy are a cause of concern.

You might stay at the clinic for a couple of weeks and then go home to continue the treatment. Or you can order a home therapy deal on the internet.

Treatment can continue for a few months to a few years. Having this therapy at home takes a great deal of time, energy and commitment. It can be almost a full-time job.

Side effects

In some situations, the Gerson diet can cause severe side effects. Some are potentially harmful. Speak to your doctor first if you are thinking of using the Gerson diet.

Coffee enemas remove a lot of potassium from your body and have been known to cause:

  • infections
  • dehydration
  • fits
  • salt and other mineral imbalances in the body
  • heart and lung problems, even death
  • constipation and inflammation of the bowel (colitis) from regular, long term use of enemas which can weaken the bowel muscle

Other reported side effects include:

  • loss of appetite
  • diarrhoea and sickness
  • abdominal cramps
  • aching, fever and sweating
  • cold sores
  • dizziness and weakness

Research into Gerson therapy for cancer

There is no evidence to prove that Gerson therapy works as a cure for cancer. We need more research to compare it with accepted and proven treatments within properly organised clinical trials.

The National Cancer Institute in the USA did a review in 2010. They found no evidence that it helped people with cancer.

Researchers in the UK did a study of 6 patients in 2007. They found that this type of therapy seemed to help people feel better emotionally. It also reduced their need for painkillers. But this number of patients is very small, so these findings are not reliable. The researchers suggested that a clinical trial is necessary. This way it will be possible to see if Gerson therapy works as a cancer treatment.

A review study in 2014 looked at 13 different cancer diets. The researchers looked at all the previous research on Gerson therapy. They found that none of the previous reports on Gerson therapy proved that it was effective.

A study looked at the 5-year survival rate of 153 cancer patients. They found that there were higher survival rates in patients with melanoma, ovarian and colorectal cancer, who were undergoing Gerson therapy. This was compared to patients having other therapies. However, this study was done by the Gerson Research Organisation. The method they used is not reliable and flawed. A further review found the evidence and study unreliable. 

It is difficult to be sure if there is any benefit in using Gerson therapy from the research so far.

This is because:

  • record keeping during studies has been quite poor
  • it is a complex therapy that can go on over months or years
  • we can’t know what other factors might or might not affect the outcome during this time, including the environment or other treatments and diets
  • some promoters give only anecdotal evidence, meaning that they use an example of an occasional person getting better as evidence

How much it costs

Gerson therapy can be costly. Do consider the ongoing cost of the treatment before you start.

You will need to buy special equipment if you are thinking of having Gerson therapy at home. Buying organic fruit, vegetables, coffee and supplements will also be an ongoing cost.

You will have to pay for flights and accommodation if you are going to a special clinic in another country. This will be on top of the treatment. Depending on the treatments involved, the cost can be thousands of pounds.

A word of caution

Some elements of the Gerson diet are healthy. For example, eating low fat food and lots of fresh fruit and vegetables.

But it is not healthy if you are eating vast quantities of one food group in a certain way (juicing) without balancing it with other food groups. It can be harmful to people who are already weak and ill. There are also many possible side effects some of which can be severe.

Most Gerson therapists encourage people not to have chemotherapy while having their therapy. This is because they believe that chemotherapy damages immunity. They say that radiotherapy is more compatible with Gerson treatment.

It is up to you to decide whether you want to use any alternative therapy. Stopping your conventional cancer treatments and methods of symptom control can be harmful.

Talk to your specialist about any alternative or complementary therapies that you want to try. Find out all you can about the therapy before deciding to use it.

Many websites are advertising or promoting Gerson therapy. But reputable scientific cancer organisations do not support them. Do not believe information or pay for alternative cancer therapy over the internet.

  • Gerson regimen

    B Cassileth

    Oncology (Williston Park). February, 2010. Vol 24, (2):201.

  • Surviving Against All Odds: Analysis of 6 Case Studies of Patients With Cancer Who Followed the Gerson Therapy

    A Molassiotis and others

    Integrative Cancer Therapies, March, 2007. Vol 6, (1), 80-88.  

  • Counseling patients on cancer diets: a review of the literature and recommendations for clinical practice.

    J Huebner and others

    Anticancer Research. 2014 January; 34(1):39-48.

  • The information on this page is based on literature searches and specialist checking. We used many references and there are too many to list here. If you need additional references for this information please contact [email protected] with details of the particular issue you are interested in.

Last reviewed: 

11 Oct 2022

Next review due: 

11 Oct 2025