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Vasopressin tablets. Desmopressin: Uses, Side Effects, and Precautions for Effective Treatment

How does desmopressin control urine production. What are the main uses of desmopressin. How should patients take desmopressin for optimal results. What are the potential side effects of desmopressin. Why is fluid intake restriction important when taking desmopressin.

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Understanding Desmopressin: A Synthetic Vasopressin Analog

Desmopressin is a synthetic analog of vasopressin, a naturally occurring hormone in the body that plays a crucial role in regulating urine production. This medication is prescribed to address various medical conditions related to excessive urination and fluid balance disorders. By mimicking the effects of vasopressin, desmopressin helps control the amount of urine produced by the kidneys, making it an essential treatment option for several conditions.

How Does Desmopressin Work?

Desmopressin functions by binding to specific receptors in the kidneys, promoting water reabsorption and reducing urine output. This mechanism of action allows the body to retain more water, which is particularly beneficial for individuals with certain medical conditions characterized by excessive urination or an inability to concentrate urine properly.

Primary Uses of Desmopressin in Medical Treatment

Desmopressin is prescribed for several medical conditions, each involving issues with urine production or fluid balance. The primary uses of this medication include:

  • Treatment of central diabetes insipidus
  • Management of nocturnal enuresis (bedwetting) in children
  • Control of excessive urination following certain types of head injuries or brain surgeries
  • Temporary treatment of excessive urination and thirst in some cases

Diabetes Insipidus Management

In cases of central diabetes insipidus, the body fails to produce sufficient amounts of vasopressin. This condition results in the production of large volumes of dilute urine, leading to excessive thirst and potential dehydration. Desmopressin effectively replaces the missing vasopressin, helping to regulate urine production and maintain proper fluid balance in the body.

Controlling Nighttime Bedwetting in Children

For children struggling with nocturnal enuresis, desmopressin can be a game-changer. The medication reduces nighttime urine production, decreasing the frequency of bedwetting episodes. This application not only improves the child’s quality of life but also boosts their confidence and social interactions.

Proper Administration of Desmopressin for Optimal Results

The effectiveness of desmopressin largely depends on its proper administration. Healthcare providers typically prescribe specific dosages and schedules based on the individual patient’s condition and needs.

Dosage and Timing for Diabetes Insipidus

For the treatment of diabetes insipidus, desmopressin is usually taken orally two to three times daily, or as directed by a healthcare professional. The exact dosage and frequency may vary depending on the severity of the condition and the patient’s response to treatment.

Administration for Bedwetting in Children

When used to manage nocturnal enuresis, desmopressin is typically administered once daily at bedtime. It’s crucial for children to limit fluid intake after dinner, especially in the hour before taking the medication and for at least 8 hours afterward. This restriction helps maximize the effectiveness of the treatment and reduces the risk of potential side effects.

Importance of Fluid Intake Restriction with Desmopressin

One of the most critical aspects of desmopressin treatment is the need for careful fluid intake management. All patients, particularly children and older adults, must adhere to strict guidelines regarding fluid consumption while taking this medication.

Why Is Fluid Restriction Necessary?

Fluid restriction is essential when taking desmopressin because the medication increases water retention in the body. Excessive fluid intake combined with the effects of desmopressin can lead to water intoxication and potentially dangerous electrolyte imbalances, particularly hyponatremia (low sodium levels in the blood).

Guidelines for Fluid Intake

Patients should consult their healthcare provider for specific instructions on fluid intake. Generally, it’s advisable to limit fluid consumption, especially around the time of medication administration. If a patient finds themselves drinking more fluids than recommended, they should inform their doctor promptly, as their treatment plan may need adjustment.

Potential Side Effects and Risks Associated with Desmopressin

While desmopressin is generally well-tolerated, it’s important for patients and caregivers to be aware of potential side effects and risks associated with its use.

Common Side Effects

Some patients may experience mild side effects when taking desmopressin, including:

  • Headache
  • Nausea
  • Upset stomach
  • Flushing of the face

These effects are usually mild and transient. However, if they persist or worsen, patients should consult their healthcare provider.

Serious Side Effects and Risks

While rare, desmopressin can cause more serious side effects, particularly related to electrolyte imbalances. The most significant risk is hyponatremia, a condition characterized by low sodium levels in the blood. Symptoms of hyponatremia may include:

  • Nausea and vomiting
  • Headache
  • Muscle weakness or cramps
  • Unusual tiredness or drowsiness
  • Dizziness
  • Restlessness
  • Mental or mood changes, including confusion and irritability

In severe cases, hyponatremia can lead to seizures or breathing difficulties. Patients experiencing these symptoms should seek immediate medical attention.

Precautions and Considerations for Desmopressin Use

To ensure safe and effective use of desmopressin, several precautions and considerations should be taken into account:

Patient Risk Factors

Certain factors may increase the risk of adverse effects, particularly hyponatremia, when taking desmopressin:

  • Age: Patients 65 years or older may be at higher risk
  • Concurrent medications: Use of diuretics or glucocorticoids may increase risk
  • Underlying medical conditions: Certain conditions may predispose patients to electrolyte imbalances

Monitoring and Follow-up

Regular monitoring is crucial for patients taking desmopressin. This typically includes:

  • Laboratory tests: Urine tests and blood sodium level checks before and during treatment
  • Regular medical appointments: To assess treatment efficacy and monitor for potential side effects
  • Symptom awareness: Patients and caregivers should be educated about signs of hyponatremia and other potential complications

Desmopressin in Special Populations: Children and Older Adults

The use of desmopressin in certain populations, particularly children and older adults, requires special consideration and careful monitoring.

Desmopressin in Pediatric Patients

When prescribed for children, especially for the treatment of nocturnal enuresis, desmopressin dosage and administration must be carefully managed. Parents and caregivers should be thoroughly educated about proper use, fluid restriction, and potential side effects. Regular follow-ups with the healthcare provider are essential to assess treatment efficacy and safety.

Considerations for Older Adults

Older adults may be more susceptible to the side effects of desmopressin, particularly hyponatremia. Dosage adjustments may be necessary, and close monitoring of electrolyte levels is crucial. Healthcare providers should carefully weigh the benefits and risks of desmopressin treatment in this population.

Interactions and Contraindications of Desmopressin

Understanding potential drug interactions and contraindications is crucial for safe desmopressin use.

Potential Drug Interactions

Desmopressin may interact with several medications, potentially altering its effectiveness or increasing the risk of side effects. Some medications that may interact with desmopressin include:

  • Diuretics (water pills)
  • Certain antidepressants
  • NSAIDs (nonsteroidal anti-inflammatory drugs)
  • Opioid pain medications
  • Certain diabetes medications

Patients should inform their healthcare provider about all medications, supplements, and herbal products they are taking to avoid potential interactions.

Contraindications

Desmopressin may not be suitable for everyone. It is contraindicated in certain conditions, including:

  • Severe renal impairment
  • Hyponatremia or a history of hyponatremia
  • Polydipsia (excessive thirst and fluid intake)
  • Certain types of heart failure
  • Known hypersensitivity to desmopressin or any components of the formulation

Healthcare providers must carefully assess a patient’s medical history and current health status before prescribing desmopressin.

Long-term Management and Follow-up for Desmopressin Therapy

Successful long-term management of conditions treated with desmopressin requires ongoing care and follow-up.

Regular Monitoring and Adjustments

Patients on long-term desmopressin therapy should undergo regular monitoring, which may include:

  • Periodic blood tests to check electrolyte levels
  • Urine output measurements
  • Assessment of symptom control and quality of life

Based on these evaluations, healthcare providers may adjust the dosage or treatment plan as needed.

Patient Education and Self-management

Empowering patients with knowledge about their condition and treatment is crucial for long-term success. This includes:

  • Understanding the importance of adherence to medication schedules
  • Recognizing signs of potential complications
  • Maintaining proper fluid intake habits
  • Knowing when to seek medical attention

Ongoing communication between patients and healthcare providers is essential for optimal management of desmopressin therapy.

DDAVP Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Warnings:

Desmopressin can rarely cause a low level of sodium in the blood (hyponatremia), which can be serious or even fatal. Drinking too much liquid, using certain medications (such as “water pills”/diuretics including furosemide, glucocorticoids such as prednisone), being 65 years or older, or having certain medical conditions may increase the risk of low sodium in the blood. Lab tests (such as urine tests, sodium blood levels) must be done before you start using this medication and while you are using it. Keep all medical and lab appointments.

Tell your doctor right away if you develop symptoms of low sodium in the blood, such as nausea, vomiting, headache, muscle weakness/cramps, unusual tiredness, unusual drowsiness, dizziness, restlessness, mental/mood changes including confusion/irritability.

Get medical help right away if you have any very serious side effects, including seizure or trouble breathing.

Warnings:

Desmopressin can rarely cause a low level of sodium in the blood (hyponatremia), which can be serious or even fatal. Drinking too much liquid, using certain medications (such as “water pills”/diuretics including furosemide, glucocorticoids such as prednisone), being 65 years or older, or having certain medical conditions may increase the risk of low sodium in the blood. Lab tests (such as urine tests, sodium blood levels) must be done before you start using this medication and while you are using it. Keep all medical and lab appointments.

Tell your doctor right away if you develop symptoms of low sodium in the blood, such as nausea, vomiting, headache, muscle weakness/cramps, unusual tiredness, unusual drowsiness, dizziness, restlessness, mental/mood changes including confusion/irritability.

Get medical help right away if you have any very serious side effects, including seizure or trouble breathing.

… Show More

Uses

Desmopressin is used to control the amount of urine your kidneys make. Normally, the amount of urine you make is controlled by a certain substance in the body called vasopressin. In people who have “water diabetes” (diabetes insipidus) or certain kinds of head injury or brain surgery, the body does not make enough vasopressin. Desmopressin is a man-made form of vasopressin and is used to replace a low level of vasopressin. This medication helps to control increased thirst and too much urination due to these conditions, and helps prevent dehydration.Desmopressin is also used to control nighttime bedwetting in children. It reduces how often your child urinates and decreases the number of bedwetting episodes.

How to use DDAVP

For the treatment of diabetes insipidus, take this medication by mouth, usually 2 to 3 times a day or as directed by your doctor.

For the treatment of bedwetting, take this medication by mouth, usually once a day at bedtime. Children should limit the fluids they drink after dinner, especially 1 hour before the desmopressin dose until the next morning, or at least 8 hours after the dose. If your child wakes up during the night, limit the amount that your child drinks.

All patients taking desmopressin, especially children and older adults, must limit drinking of water and other fluids. Consult your doctor for details. If you find that you are drinking more fluids than directed, tell your doctor right away. Your treatment will need to be adjusted.

Dosage is based on your medical condition and response to treatment. Do not take more desmopressin or take it more often than prescribed.

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

Tell your doctor if your condition does not improve or if this medication stops working well.

Side Effects

See also Warning section.

Headache, nausea, upset stomach, or flushing of the face may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking desmopressin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, high blood pressure, heart problems (such as blocked blood vessels, heart failure), conditions that may increase your risk of fluid/mineral imbalance (such as cystic fibrosis), the urge to drink too much water without being thirsty, a low level of sodium in the blood (hyponatremia), bleeding/clotting problems.

If you become dehydrated, your doctor will correct that condition first before starting treatment with desmopressin.

Limit alcohol because it can interfere with how well desmopressin works.

Tell the doctor right away if you develop any illness that can cause water/mineral imbalance (including fever, diarrhea, vomiting, infections such as the flu) or if you experience conditions that require drinking more fluids (for example, exposure to very hot weather, strenuous exercise, heavy sweating). The doctor may need to stop or adjust desmopressin treatment, especially in children and older adults.

Children may be more sensitive to the side effects of this drug, especially water/mineral imbalance and a low level of sodium in the blood.

Older adults may be at greater risk for water/mineral imbalance and a low level of sodium in the blood while using this drug.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Some products that may interact with this drug are: tolvaptan, “water pills”/diuretics (such as furosemide).

Does DDAVP interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: headache that is severe or doesn’t go away, confusion, drowsiness, sudden weight gain.

Do not share this medication with others.

Lab and/or medical tests (such as urine tests, sodium blood level) may be done while you are taking this medication. Keep all medical and lab appointments. Consult your doctor for more details.

If you take 1 dose daily and miss a dose, take it as soon as you remember. If you do not remember until the next day, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

If you take more than 1 dose daily and miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Images

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DDAVP 0.1 mg tablet

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

tolvaptan oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Warnings:

Treatment with this drug should be started or restarted in a hospital for proper monitoring. If your level of sodium in the blood is raised too quickly, it may cause a serious (even fatal) condition called osmotic demyelination syndrome. The risk is higher if you have liver disease, poor nutrition, or if you use/abuse alcohol. Tell your doctor right away if you have symptoms such as trouble speaking/swallowing, mental/mood changes (such as confusion), weakness/involuntary movement in the arms/legs, or seizures.

Do not use this medication to treat a certain kidney problem (autosomal dominant polycystic kidney disease-ADPKD). Due to the risk of serious liver damage, you must be in a special program for you to take this medication to treat ADPKD. Ask your doctor for details.

How to use Tolvaptan 30 Mg Tablet Antidiuretic Hormone Antagonists

Read the Medication Guide provided by your pharmacist before you start using tolvaptan and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually once daily. You should not take this medication for longer than 30 days.

To prevent dehydration, always have water ready to drink while taking tolvaptan. Drink when you are thirsty unless otherwise directed by your doctor.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Do not stop and restart this medication on your own. You may need to go back to a hospital to restart this medication. Tell your doctor right away if you stop taking this medication for any reason.

Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details.

The dosage is based on your medical condition and response to treatment.

Side Effects

See also Warning section.

Thirst, dry mouth, loss of appetite, constipation, or weakness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Dehydration can occur. The risk is increased if you have vomiting or diarrhea that doesn’t stop, and you cannot drink normally. Contact your doctor right away if you notice any symptoms of dehydration, such as fast heartbeat or dizziness/lightheadedness.

People with severe liver disease (cirrhosis) may have increased risk of bleeding from the stomach or intestines while taking this medication. Tell your doctor right away if you have any of the following symptoms: black/bloody stools, vomit that contains blood or looks like coffee grounds.

Tolvaptan may rarely cause serious (possibly fatal) liver disease. Get medical help right away if you have any symptoms of liver damage, such as: nausea/vomiting that doesn’t stop, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking tolvaptan, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, liver disease, trouble urinating (such as due to enlarged prostate, blockage, inability to make urine), use/abuse of alcohol.

To prevent dehydration while taking this medication, you must be able to replace fluids by drinking. Before taking this medication, tell your doctor if you are not able to drink normally or if you cannot feel if you are thirsty. (See also How to Use section.)

This medication may rarely make your blood sugar rise, which can cause or worsen diabetes. If you have diabetes, check your blood sugar regularly as directed and share the results with your doctor. Your doctor may need to adjust your diabetes medication, exercise program, or diet.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Consult your pharmacist or physician.

Interactions

See also How to Use section.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

A product that may interact with this drug is: desmopressin.

Other medications can affect the removal of tolvaptan from your body, which may affect how tolvaptan works. Examples include azole antifungals (such as ketoconazole, itraconazole), cobicistat, HIV protease inhibitors (such as lopinavir), macrolide antibiotics (such as clarithromycin, erythromycin), ribociclib, rifamycins (such as rifabutin, rifampin), ritonavir, St. John’s wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others.

Does Tolvaptan 30 Mg Tablet Antidiuretic Hormone Antagonists interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Do not share this medication with others.

Lab and/or medical tests (such as levels of sodium/potassium in the blood) should be done while you are taking this medication. Keep all medical and lab appointments.

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Images

tolvaptan 30 mg tablet

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This medicine is a blue, round, tablet imprinted with “OTSUKA 30”.

tolvaptan 15 mg tablet

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This medicine is a blue, round, tablet imprinted with “OTSUKA 30”.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Fidelity Pills – KP.RU

Komsomolskaya Pravda

Search results 004 Scientists are encouraging: a substance has been found on the basis of which it is possible to create a drug against adultery

As it turned out, as many as two issues of the “Man and Woman” column, which were devoted to the scientific search for the reasons for going to the left and ways to stop them, did not cover the whole variety of topics (“Is there a cure for adultery?”, “Coercion to fidelity”, see . “KP” dated September 6 and 13, 2008). Recently, new discoveries have arrived. And they testify: not only instincts and psychology are involved in adultery. But also chemistry. A substance has been discovered that averts fornication and generates a sense of fidelity to a single partner. Thanks to him, according to scientists, next to us there are people who can not change.

Cheating genes

The search for the chemical causes of infidelity began about seven years ago. And, as usual, from experiments on mice. Fortunately, among these animals there are two amazing populations – meadow voles and steppe voles. The males of the first are extremely lascivious, mating right and left. And those from the second, all their mouse life remain faithful to one female. Scientists decided to figure out why such a miracle happens. And they seem to have figured it out.

“Our study, in a relatively simple biological model, provides evidence that boosting the activity of just one gene profoundly changes the foundations of social behavior,” said Larry Young, a professor at Emory University in Georgia.

It turned out that the heads of faithful and unfaithful mice contain a different number of receptors that perceive the hormone vasopressin. It is produced by the brain in one area, and absorbed in another. This hormone, scientists have suggested, and generates a sense of attachment. Moreover, it creates a very pleasant feeling that one female is enough to satisfy sexual needs. The bold hypothesis was also reinforced by the fact that the faithful mice showed an excess of both the hormone itself and the receptors that perceive it.

To test, American neuroscientists transferred the gene responsible for vasopressin receptors from monogamous steppe voles to meadow lovers to go left. And a fantastic transformation happened: the Casanova mice became faithful “husbands” without exception. This is the magical power of chemistry.

People are like mice

Impressive results were obtained back in 2004. But since they belonged to “simple biological models”, they did not create confidence that they could be transferred to more complex ones – to people. Doubts were dispelled by recent research conducted at the Swedish Karolinska Institute under the direction of Professor Hass Walum. Scientists have discovered a striking similarity between people and their smaller brothers in terms of the chemical nature of adultery. It turned out that the human brain interacts with vasopressin in exactly the same way as the mouse. Faithful men found more of the hormone, and it was absorbed better. For cheaters, the opposite is true. And the reason is the same – the genetic difference of one from the other.

Conclusions: vasopressin has a serious claim to be the human hormone of fidelity. This is first. Secondly, not all men are cheaters. There is a breed of people in whom nature has beaten off the inclination to fornication, while retaining both the libido and the ability to receive sincere satisfaction from sexual intercourse with a single partner. Such, according to opinion polls, from a quarter to a third of the stronger sex.

Alas, it is still a mystery whether there is a genetic difference between women of easy sexual behavior and those who profess marital fidelity.

Prescribe me, doctor…

Vasopressin is a known hormone. News – its role in human relationships and in influencing social behavior. Naturally, the question arises: is it possible, on the basis of this hormone, to create a drug for the “treatment” of infidelity? Theoretically – yes, scientists answer. But more research is needed. After all, it is stupid to drink vasopressin or inject it dangerously. Like any hormone. Yes, and there are side effects – the most famous, for example, difficult urination (analogs of vasopressin are prescribed for patients with enuresis). Would a healthy husband in this sense want to make such a sacrifice? However, medical science does not stand still. Scientists will come up with something – synthetically harmless. And make humanity happy with fidelity pills.

Vladimir LAGOVSKY

SPECIALIST’S OPINION

Dilute with tenderness!

Natalia GRIDASOVA, psychoendocrinologist, doctor of the highest category:

– Vasopressin belongs to a group of hormones that are produced by a very important part of the brain – the pituitary gland, and is responsible for regulating the amount of fluids in the body. And disinhibited sexual behavior (simply – pathological infidelity) is often distinguished by people who have just the same function of the pituitary gland.

Of course, it is impossible to say directly, they say, inject your “walker” with vasopressin, and he will sit beside you like silk. But perhaps there is a rational grain in these studies. And the medicine “for infidelity” will act just on those men who run to the left not because of natural depravity or because the partner does not suit, but “due to illness.”

Vasopressin also affects the secretion of oxytocin, the hormone of tenderness, which is responsible for the emotional component of sexual relations and enhances attachment to a partner.

In large doses, vasopressin greatly increases pressure in tissues, including the brain, and this can be very dangerous for health.

Elena IONOVA.

BTW

Sleep well

Endocrinologists at the Faculty of Medicine of the University of Lübeck, led by Jan Born, discovered that inhaling an aerosol preparation containing vasopressin in the morning and evening has a hypnotic effect. But it also weakens memory.

In principle, an attractive combination of side effects: a faithful husband sleeps well, pees little and does not remember insults.

Maybe scientists are trying in vain? There is little demand for chastity pills. Slightly higher than on a baldness balm. It is strange, however… Although there are suspicions that in our sociological survey mainly traitors participated, for whom some kind of “non-leftist” is a threat to a lustful lifestyle. Like bromine for Casanova. Or do people really cope with adultery non-drug? Through love and willpower? And rely on natural feelings? Showing no interest even in a love potion?

Another interpretation is not ruled out. Logically sound. After all, if you restore a peppy and fresh look, become smart and slender teetotalers, then other problems – partner’s infidelity, baldness and insufficient attention of the opposite sex – will seem secondary and easily solved. This is what Faust thought when he sold his soul. Looks like we haven’t changed much since then?

Vladimir Lagovsky is waiting for your feedback on our website.

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