How do topical vitamin D analogs work in treating psoriasis. What are the benefits and side effects of vitamin D ointments for psoriasis. Which vitamin D analogs are most effective for managing psoriatic plaques. How do vitamin D treatments compare to other topical psoriasis therapies.

Understanding Psoriasis and Its Impact on Patients

Psoriasis is a chronic autoimmune skin condition characterized by red, scaly patches that can be itchy and painful. It affects millions of people worldwide and can have a significant impact on quality of life.

Studies have shown that psoriasis causes as much disability as other major medical conditions. A survey by the National Psoriasis Foundation found that:

• 75% of patients reported that psoriasis had moderate to large negative impact on their quality of life
• Many experienced depression, anxiety, and social isolation due to their condition
• The economic burden is substantial, with high direct and indirect costs

Given its prevalence and impact, developing effective treatments for psoriasis remains an important goal in dermatology research and clinical practice.

The Role of Vitamin D in Skin Health and Psoriasis

Vitamin D plays a crucial role in skin health and immune function. In psoriasis, vitamin D is believed to help normalize skin cell growth and reduce inflammation.

How exactly does vitamin D affect psoriatic skin? It has several key actions:

• Inhibits proliferation of keratinocytes (skin cells)
• Promotes differentiation of skin cells
• Modulates immune responses in the skin
• Suppresses inflammatory mediators

These effects make vitamin D analogs a logical treatment option for managing the abnormal skin cell growth and inflammation seen in psoriatic plaques.

Topical Vitamin D Analogs: Mechanism of Action

Vitamin D analogs used topically for psoriasis are synthetic derivatives of vitamin D3. They work by binding to vitamin D receptors in skin cells and immune cells.

What happens when vitamin D analogs bind to these receptors? This binding triggers several key effects:

1. Decreased proliferation of keratinocytes
2. Increased differentiation of skin cells
3. Modulation of inflammatory and immune responses
4. Normalization of keratinocyte maturation

Through these actions, topical vitamin D treatments can help reduce the scaling, thickness, and inflammation of psoriatic plaques. They address both the epidermal hyperproliferation and immune dysregulation involved in psoriasis pathogenesis.

Types of Topical Vitamin D Analogs for Psoriasis

Several vitamin D analogs have been developed for topical use in psoriasis. The most commonly used include:

• Calcipotriol (calcipotriene)
• Calcitriol
• Tacalcitol

How do these different analogs compare in efficacy? Studies have shown comparable effectiveness between calcipotriol and calcitriol. Tacalcitol may be slightly less potent but can be used in once-daily application.

Calcipotriol is available as an ointment, cream, solution, and foam. Calcitriol comes as an ointment. The choice between formulations often depends on the body area being treated and patient preference.

Efficacy of Vitamin D Analogs in Psoriasis Treatment

Clinical trials have demonstrated the effectiveness of topical vitamin D analogs in improving psoriasis symptoms. Key findings include:

• Significant reduction in scaling, erythema, and plaque thickness compared to placebo
• Improvement in 30-50% of patients after 4-6 weeks of treatment
• Comparable efficacy to moderate-potency topical corticosteroids
• Sustained improvement with long-term use

Are vitamin D analogs effective for all types of psoriasis? They work best for mild to moderate chronic plaque psoriasis. They may be less effective for severe psoriasis or other variants like pustular or erythrodermic psoriasis.

Safety and Tolerability of Topical Vitamin D Treatments

Vitamin D analogs are generally well-tolerated when used as directed. Common side effects may include:

• Mild skin irritation
• Burning or itching sensation
• Dry skin

These effects are usually mild and tend to improve with continued use. Serious adverse events are rare with topical application.

Is there a risk of systemic side effects? When used appropriately, topical vitamin D analogs have minimal systemic absorption and do not significantly affect calcium metabolism. However, excessive use over large body surface areas should be avoided.

Comparing Vitamin D Analogs to Other Psoriasis Treatments

How do vitamin D treatments stack up against other topical psoriasis therapies? Let’s compare:

Vitamin D Analogs vs. Topical Corticosteroids

• Similar efficacy for mild-moderate psoriasis
• Vitamin D analogs have a slower onset but better safety profile for long-term use
• Combination therapy often provides synergistic effects

Vitamin D Analogs vs. Topical Retinoids

• Comparable efficacy
• Vitamin D analogs tend to be better tolerated
• Retinoids may work faster but cause more irritation

Vitamin D Analogs vs. Coal Tar

• Vitamin D analogs are more cosmetically acceptable
• Coal tar may be more effective for scalp psoriasis
• Both have similar efficacy for plaque psoriasis

The choice between treatments often depends on factors like psoriasis severity, affected body areas, patient preference, and cost considerations.

Optimizing Treatment with Vitamin D Analogs

To maximize the benefits of topical vitamin D therapy for psoriasis, consider these tips:

1. Apply to clean, dry skin
2. Use as directed, typically once or twice daily
3. Avoid excessive application or occlusion unless advised by a doctor
4. Be patient – improvement may take several weeks
5. Consider combination therapy with other agents for enhanced efficacy
6. Monitor for side effects and adjust usage if needed

Is there an optimal way to combine vitamin D analogs with other treatments? Many dermatologists recommend using vitamin D analogs in the morning and topical corticosteroids at night. This approach may provide synergistic effects while minimizing potential side effects of each treatment.

Future Directions in Vitamin D-Based Psoriasis Therapy

Research continues to explore new ways to harness the therapeutic potential of vitamin D in psoriasis treatment. Some promising areas of investigation include:

• Development of new vitamin D analogs with improved efficacy and safety profiles
• Novel drug delivery systems to enhance skin penetration and reduce systemic absorption
• Combination therapies that leverage synergistic effects with other agents
• Better understanding of the molecular mechanisms underlying vitamin D’s effects in psoriatic skin

Will we see more advanced vitamin D-based treatments in the future? It’s likely that ongoing research will lead to refinements in existing therapies and potentially new treatment approaches leveraging vitamin D’s effects on skin and immune function.

As our understanding of psoriasis pathogenesis and the role of vitamin D continues to evolve, topical vitamin D analogs are likely to remain an important component of psoriasis management strategies. Their efficacy, favorable safety profile, and potential for combination with other treatments make them a valuable option for many patients with mild to moderate plaque psoriasis.

While not a cure, vitamin D analogs offer a way to manage symptoms, improve quality of life, and potentially modify the course of the disease for some individuals with psoriasis. As with any medical treatment, patients should work closely with their healthcare providers to determine the most appropriate approach for their individual needs and circumstances.

The Rationale Behind Topical Vitamin D Analogs in the Treatment of Psoriasis

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Psoriasis treatment: Synthetic vitamin D

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which pharmacologist recommends? Top 10 best drugs

Content

• 1 Top 10 psoriasis drugs according to an expert in pharmacology
  • 1.1 Pharmacological recommendations for psoriasis drugs
  • 1.2 What is the problem in treating psoriasis?
  • 1.3 What are the most common treatments?
  • 1.4 What drugs are prescribed at the first visit to the doctor?
  • 1.5 What drugs are used in the treatment of psoriasis on a long-term basis?
  • 1.6 Prescribing methotrexate products for the treatment of extensive dermatoses
    • 1.6.1 What is methotrexate and how does it work?
    • 1.6.2 Prescribing methotrexate for psoriasis
    • 1.6.3 How to take methotrexate for psoriasis?
  • 1. 7 Oral psoriasis drugs
  • 1.8 How do charcoal drugs work on psoriasis?
  • 1.9 Medicines for psoriasis: What medicines are used to treat the articular manifestations of psoriasis?
  • 1.10 Vitamin D preparations in the treatment of psoriasis
    • 1.10.1 Vitamin D in the body
    • 1.10.2 Effect of vitamin D preparations in the treatment of psoriasis
    • 1.10.3 Side effects

    90 008

  • 1.11 Use of carbon dioxide in treatment of psoriasis
  • 1.12 Related videos:
  • 1.13 Q&A:
    • • 1.13.0.1 What is psoriasis and how is it treated?
      • 1.13.0.2 What drugs are in the top 10 best psoriasis remedies?
      • 1.13.0.3 How does Soriatan work?
      • 1.13.0.4 Can ointments and creams be used together with systemic treatment?
      • 1.13.0.5 What are the possible side effects of systemic treatment of psoriasis?
      • 1.13.0.6 What is infliximab and how does it help with psoriasis?
      • 1.13. 0.7 Are there alternative treatments for psoriasis?
      • 1.13.0.8 Which of the top 10 drugs is most effective?

Pharmacologist talks about 10 remedies for psoriasis, their effectiveness and use. Learn how to properly treat psoriasis and reduce its symptoms.

Psoriasis is one of the most common skin diseases that can significantly reduce the quality of life and cause irreparable damage to a person. Currently, many pharmacological companies offer various drugs to combat this disease.

Choosing the right medication for the treatment of psoriasis is not an easy task. Each patient has his own characteristics and, consequently, his own treatment needs. It is desirable to choose an effective and safe remedy, but alas, this is not always possible. With all this in mind, we have prepared for you the top 10 best drugs recommended by pharmacologists for the treatment of psoriasis.

Attention! It is important to note that no article can replace medical advice and recommendations from a specialist. Before you start using any drug, it is important to consult your doctor and go through all the necessary examinations.

Pharmacological guidelines for psoriasis remedies

Psoriasis is a chronic inflammatory skin disease that can be very difficult to treat. There are many different treatments for psoriasis, but which ones do pharmacologists recommend?

One of the most recommended topical preparations for the treatment of psoriasis are ointments based on glucocorticosteroids. They can quickly relieve itching and reduce inflammation, making them especially useful for quickly relieving symptoms.

Oral medications are also effective for treating psoriasis, including antibiotics, methotrexate, and retinoids. However, they have their drawbacks, such as a higher risk of side effects and the need to take on a schedule, which requires a lot of discipline from the patient.

When choosing a drug for the treatment of psoriasis, it is important to take into account the individual characteristics of the patient, as well as the characteristics of the nature of the disease. Pharmacologists can help determine the most effective and safe course of treatment, so feel free to contact them for advice.

What is the problem in treating psoriasis?

Psoriasis is a chronic skin condition that can lead to significant discomfort and reduced quality of life. Being an immune systemic reaction, psoriasis can be treated, but there is no universal remedy that would effectively act on all cases of the disease. In other words, each patient needs an individual approach to the treatment of psoriasis, and finding the best way can take time.

The problem is that psoriasis can manifest itself in different forms and degrees. This means that various methods and means are used for treatment, but it is necessary to have tremendous experience and knowledge in order to correctly determine which method and which means to use in a particular case. Moreover, it is quite difficult to achieve a complete cure in the treatment of psoriasis, so many factors must be taken into account in order to ensure the best treatment effect with a minimum of side effects.

Therefore, the choice of psoriasis treatments should be informed, based on medical data and analysis, and always tailored to the individual patient. That is why in this topic we will consider the 10 most effective drugs recommended by a pharmacologist and which can help in the fight against psoriasis in its various manifestations and degrees.

What are the most common treatments?

Psoriasis is a chronic skin disease that can lead to significant discomfort and even disability. Treatment for this disease can be difficult and ineffective. Some patients may suffer from severe forms of psoriasis that require systemic treatment.

Ointments and creams containing salicylic acid, glucocorticosteroids and vitamin D help many patients. In some cases, they can be used in combination.

Light therapy can also be helpful for psoriasis. Phototherapy uses light to reduce inflammation, reduce the risk of wounds, and reduce bacteria and viruses that can contribute to infection.

Medicines taken by mouth, such as methotrexate and calciareol, can help with more severe cases of psoriasis. However, they can cause side effects such as nausea, vomiting, headache, and others.

Drug treatments are also available, but they are used much less frequently than other methods because they can be hazardous to health.

What drugs are prescribed at the first visit to the doctor?

At the first visit to the doctor, patients with psoriasis may be prescribed various drugs, depending on the degree and type of skin lesions. Some of them can stop the growth of skin lesions, others can reduce inflammation and itching, and some help heal and regenerate damaged skin.

Among the most commonly used drugs at the first stage of psoriasis treatment are: ointments based on glucocorticosteroids, creams with acetylsalicylic acid, antiseptics and antifungal drugs.

• Ointments based on glucocorticosteroids. These are classic medicines that help relieve inflammation and itching. They contain hormones that provide fast and effective treatment for the symptoms of psoriasis. But their use should be short-term and under the supervision of a doctor, as there may be side effects.
• Creams with acetylsalicylic acid. They reduce inflammation and soften the horny layer of the skin, making it easier to remove inflamed scales. In addition, they have antifungal properties and prevent infections in wounds and scratches.
• Antiseptics and antifungals. They help to avoid possible complications as a result of infection of wounds. They are used in the form of ointments, creams and sprays. Some of them contain antibiotics that kill pathogens.

However, do not forget that the prescription of drugs in the treatment of psoriasis should always be individual and depend on the type and extent of the disease, which emphasizes the importance of consulting a doctor.

What drugs are used in the treatment of psoriasis on a long-term basis?

Psoriasis is a chronic disease that requires long-term and systematic treatment. Various agents are used to control symptoms and prevent flare-ups of psoriasis. They may or may not be medicinal, depending on the extent and severity of psoriasis.

Systemic therapies such as immunosuppressants, retinoids, and biologics may also be used to treat psoriasis on a long-term basis. They have a more pronounced effect on the regulation of the immune system and on stopping the formation of the disease.

In addition to drugs, non-pharmacological methods can also be prescribed in the treatment of psoriasis. For example, the level of exposure to sunlight on the disease of psoriasis is proven by doctors and is used to treat the disease. In addition, it is important to follow proper nutrition, constant skin care and overall health.

Incorrect use of drugs can lead to negative consequences, so you must strictly follow the doctor’s recommendations when treating psoriasis on a long-term basis and do not self-treat in any way.

Prescription of methotrexate-based drugs for the treatment of extensive dermatoses

What is methotrexate and how does it work?

Methotrexate is a drug that belongs to the class of cytotoxic chemotherapy drugs. In medicine, it is widely used to treat a number of diseases, including cancer, rheumatoid arthritis, autoimmune diseases, and psoriasis.

The mechanism of action of methotrexate is that it slows down the growth and reproduction of cells, including other pathological cells that cause various diseases, including psoriasis.

Prescription of methotrexate for the treatment of psoriasis

Methotrexate is one of the most effective drugs for the treatment of extensive dermatoses such as psoriasis.

However, its administration requires careful attention from the doctor, as methotrexate has certain side effects that can affect the functioning of certain organs, such as the liver, lungs, kidneys, and bone marrow.

Prescription of methotrexate for the treatment of psoriasis is carried out only for a long course of the disease and when other methods of treatment do not cope with the task.

How to take methotrexate for psoriasis?

The dosage of methotrexate for the treatment of psoriasis may differ from that prescribed for the treatment of other diseases. Due to the fact that methotrexate can cause serious side effects, the doctor must prescribe an individual dose for each patient.

Methotrexate is usually taken as a tablet or injection. Before starting treatment, it is necessary to conduct blood tests, an ultrasound examination of internal organs, as well as a consultation with a cardiologist and pulmonologist.

It is also not recommended to drink alcohol during treatment with methotrexate and to use certain drugs that can exacerbate side effects.

Oral psoriasis drugs

Psoriasis is a chronic skin disease that cannot be completely cured but can be controlled with a variety of treatments, including oral medications.

Oral treatments:

1. Retinoids are vitamin A analogs that regulate skin cell turnover. They are often used in severe cases of psoriasis, but have many side effects and should only be used under strict medical supervision.
2. Methotrexate is an immunosuppressive medicine used to reduce the activity of the immune system. It can help control psoriasis, but it can also have serious side effects, including damage to the liver and bone marrow.
3. Acitretin is a retinoid analogue that also regulates skin cell renewal. It can be used in place of retinoids in some cases, but is less effective and has fewer side effects.
4. Cyclosporine is an immunosuppressive drug that blocks certain signals in the immune system, resulting in a decrease in the activity of psoriatic lesions. It can be effective, but it can also affect kidney function and other organs.

Before starting treatment for psoriasis with oral medications, you should always consult a doctor who will provide you with all the information you need about these medications and help you choose the most appropriate treatment option for your particular situation.

How do charcoal drugs work on psoriasis?

Psoriasis is a chronic disease that can lead to various skin manifestations. Charcoal preparations can help reduce the symptoms of psoriasis through their effect on the body.

Charcoal preparations absorb toxins and waste products that can worsen psoriasis skin. In addition, such drugs can help reduce inflammation and reduce itching, which can also significantly improve the condition of the patient.

Charcoal may be one of the many components in the treatment of psoriasis. It is important to discuss with your doctor the appropriate dosage of charcoal, as well as the regularity of intake, in order to reduce the possibility of side effects.

• Activated charcoal is the most commonly used charcoal preparation. It can be used both internally and externally to treat affected areas of the skin.
• Carbolene is a charcoal preparation that can be used to treat psoriasis by mouth. It can also be used to cleanse the skin.
• Norit is a charcoal preparation that can help cleanse the body and reduce the level of toxins in the body. It can be taken as a food supplement or taken internally.
• Polysorb m is a charcoal formulation that may help clear the skin and reduce inflammation in psoriasis. It can be taken as a food supplement or taken internally.

In any case, it is important to communicate with your doctor and integrate charcoal preparations into your individual psoriasis treatment plan appropriately.

Medicines for psoriasis: What medicines are used to treat the articular manifestations of psoriasis?

Articular manifestations of psoriasis is one of the most severe forms of the disease that requires complex treatment. For effective therapy, several groups of drugs are used.

First of all, your doctor may prescribe non-steroidal anti-inflammatory drugs (NSAIDs), such as diclofenac, naproxen, ibuprofen, etc. They help reduce pain and inflammation in the joints, improve their mobility and general well-being.

If NSAIDs do not help, glucocorticosteroids, powerful anti-inflammatory drugs that can be administered either intramuscularly or intravenously, may be prescribed. Their use is accompanied by the risk of side effects, so they are used as short-term courses, under the supervision of a physician.

An important place in the treatment of articular manifestations of psoriasis is occupied by biological drugs – drugs that block certain cytokines responsible for the development of inflammation in the joints. To date, there are several representatives of this group of drugs that have shown good results in the treatment of articular manifestations of psoriasis.

In addition, the following preparations can be included in complex therapy: wipes based on salicylic acid, ointments with glucocorticosteroids, Aimalgel ointment, chondroitin and glucosamine preparations. Their choice and dosage should be agreed with the doctor.

Vitamin D preparations for the treatment of psoriasis

Vitamin D in the body

Vitamin D is an essential nutrient and plays a key role in the regulation of calcium and phosphate in the body. Its deficiency can lead to various diseases, including psoriasis.

The effect of vitamin D preparations in the treatment of psoriasis

Vitamin D is the main component of many drugs used in the treatment of psoriasis. These medications can help reduce inflammation and irritation of the skin, as well as slow the growth of skin cells, which can reduce the symptoms of psoriasis.

The most common vitamin D preparations are calcipotriol (Dovonex), calcipotriene (Vectical), and tacalcitol (Silkis).

Side effects

Vitamin D preparations are generally well tolerated by patients with psoriasis, but some side effects may be observed, including skin irritation, dryness and itching.

It is also important not to exceed the recommended dose, as vitamin D can accumulate in the body and cause problems with the kidneys and other organs.

The use of carbon dioxide in the treatment of psoriasis

Carbon dioxide can be used as a therapeutic agent in the treatment of psoriasis. This gas can help improve circulation, which can reduce inflammation and speed up skin healing.

There are several preparations that contain carbon dioxide and can be used in the treatment of psoriasis. One such drug is carboxytherapy, which involves injecting carbon dioxide into the skin using small needles.

Another preparation containing carbon dioxide is thermal water, which can be used to reduce the inflammation and itching associated with psoriasis. It can also help hydrate the skin and reduce flaking.

However, before you start using these drugs, you should consult a specialist. Treatment of psoriasis should be complex and individual, and only a qualified doctor can choose the most appropriate set of drugs, including those that contain carbon dioxide.

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Q&A:

What is psoriasis and how is it treated?

Psoriasis is a chronic non-infectious skin disease that manifests itself in the form of rashes on different areas of the skin. Treatment of psoriasis directly depends on the severity of the disease. At an early stage, ointments and creams with active ingredients can be used; in severe stages, systemic treatment may be necessary.

What drugs are in the top 10 best remedies for psoriasis?

Top 10 best psoriasis remedies include: Soriatan, Cyclosporine, Methotrexate, Infliximab, Adalimumab, Etanercept, Ustekinumab, Golimumab, Apremilast, Secuckinumab.

How does Soriatan work?

Soriatan is a drug that acts as an immunosuppressant. It suppresses the immune responses in the body that cause psoriasis, thereby reducing the symptoms of the disease.

Can ointments and creams be used together with systemic treatment?

Yes, you can combine ointments and creams with systemic treatments to get the most out of your treatment. But you should watch out for possible side effects and consult your doctor.

What are the possible side effects of systemic psoriasis treatment?

Side effects of systemic treatment for psoriasis may include nausea, headache, elevated liver enzymes, reduced immunity, or risk of infections.

What is infliximab and how does it help with psoriasis?

Infliximab is a drug that blocks the activity of a protein responsible for causing inflammation in the body. The use of this drug can reduce inflammation, reduce the symptoms of psoriasis, and improve patients’ quality of life.

Are there alternative treatments for psoriasis?

Yes, there are alternative treatments for psoriasis, such as phototherapy, relaxation techniques, or dietary changes. However, these methods cannot be a substitute for systemic treatment and a physician should be consulted before using them.

Which of the top 10 drugs is most effective?

The choice of the most effective drug for the treatment of psoriasis depends on the individual characteristics of each patient, the severity of the disease and many other factors. But at the moment, etanercept is one of the most effective drugs in the treatment of psoriasis.

rating of the top 10 inexpensive and effective remedies according to the KP

Treatment of psoriasis is a difficult task for the doctor and for the patient. One of the important points of treatment is the appointment of vitamins. We will find out from an expert in which cases taking vitamins will be effective, which drugs are better to choose, and whether they have contraindications.

Rating of the top 10 inexpensive and effective vitamins for psoriasis according to KP

Important! Any drugs and dietary supplements have side effects and contraindications. Our material is an overview and does not serve as a guide to action. Before buying funds, consult your doctor.

Pentovit Altaivitamins

B vitamins, in particular B1, B6 and B12 are often used in the treatment of patients with psoriasis ¹ . The drug Pentovit contains these vitamins in combination with folic acid. B vitamins are involved in the most important metabolic processes, help improve skin condition and speed up the healing of damage. In addition, they have a positive effect on the state of the nervous system – the central and peripheral ² .

Pentovit is available as tablets and is intended for people over 18 years of age.

Contraindications : individual intolerance, pregnancy.

Aevit Tula factory

The drug is produced in the form of yellow or brown soft capsules, inside which there is an oily liquid ³ . The product contains a combination of vitamins A and E, which have an antioxidant effect and increase the body’s resistance to negative environmental influences. Vitamin A is actively involved in the process of cell division and growth of epithelial tissues and skin, and vitamin E is necessary for the synthesis of collagen and elastin, the structural elements of the skin. That is why vitamins A and E are used in the treatment of many skin diseases ¹ .

Aevit is prescribed for deficiency of vitamins A and E and is used in the complex therapy of skin diseases: psoriasis, ichthyosis, seborrheic dermatitis, some forms of eczema ³ .

Contraindications : pregnancy and lactation, hypersensitivity to components, age under 18, hypervitaminosis A and/or E.

Vitamin E 400 mg

Vitamin E is an antioxidant that helps strengthen cell walls, improve tissue metabolism , accelerate the healing and regeneration processes ⁴ . Due to its properties, vitamin E can be used in the complex therapy of psoriasis, including for external use ⁵ .

The drug is available in the form of light yellow oval capsules with an oily liquid inside. Indicated for use in case of deficiency of vitamin E in the body. Use during pregnancy and lactation is possible only on prescription.

Solgar Zinc Picolinate

Solgar Zinc Picolinate is recommended as an additional source of zinc. This trace element is considered a powerful antioxidant and helps the body resist and fight infections. In addition, zinc regulates the activity of the sebaceous glands and helps to cope with oily sheen and various skin rashes. The action of the bioadditive is aimed at strengthening the immune system and improving the condition of the skin, hair and nails.

Contraindications : age under 18, pregnancy, breast-feeding, hypersensitivity to the components of the drug.

Losterin vitamin-mineral complex

Dietary supplement Losterin is designed to compensate for vitamin and mineral deficiency and reduce the risk of developing chronic skin diseases: psoriasis, seborrheic dermatitis, xerosis, keratoderma, ichthyosis ⁶ .

The dietary supplement contains 10 vitamins (including vitamins A, E, C, D, beta-carotene, B vitamins), trace elements, omega-3, beta-carotene and silymarin for the normal functioning of the liver and gallbladder. The action of the components is aimed at restoring metabolic and redox processes in skin cells, accelerating regeneration and reducing inflammation ⁶ . The package contains an equal number of red and white capsules with a different set of active ingredients.

Contraindications : individual intolerance to the components, pregnancy and lactation. It is recommended to consult a doctor before taking it.

Detrimax 2000 IU

Vitamin D3 deficiency may reduce the ability of the skin to recover, causing the inflammatory process to develop faster. In the course of the research, Irish scientists compared the results of analyzes of patients with psoriasis in different periods. Most of them had a low content of vitamin D3 in the blood – especially in the winter and spring months, when there is very little sun. It was during this period that patients began to exacerbate psoriasis, and psoriatic plaques were especially pronounced ^7.8 .

Bioadditive Detrimax can become an additional source of vitamin D3. The dietary supplement is available in the form of tablets, each of which contains 2000 IU of vitamin D3.

Contraindications : age under 18, individual intolerance.

Selzinc Plus

Dietary supplement Selzinc Plus contains vitamins and minerals with antioxidant action: selenium, zinc, vitamins E and C, beta-carotene. The drug enhances the body’s natural defenses against viral and bacterial infections, helps to recover faster after illnesses. The active components of dietary supplements improve the processes of skin renewal, have an anti-inflammatory effect, and reduce excessive activity of the sebaceous glands.

Contraindications : age under 18, pregnancy and lactation, individual intolerance to the components.

Perfectil Plus

Dietary supplement Perfectil Plus is recommended for use as an additional source of carotenoids, coenzyme Q10, omega-3 and omega-6 polyunsaturated fatty acids, vitamins C, D, E, PP and group B. The active components of the dietary supplement have antioxidant action, support normal metabolism in skin cells, help improve its blood supply and nutrition. 1 package contains 28 tablets and 28 capsules. Tablets and capsules have a different composition: the manufacturer combined the active ingredients in such a way that they are better absorbed.

Contraindications : age under 18 years, individual intolerance, pregnancy, lactation and conditions in which iodine preparations are contraindicated. Patients with thyroid disease should consult their doctor before taking dietary supplements.

Special Dragee Merz Classic

The purpose of this dietary supplement is to maintain healthy skin, nails and hair. The action of dietary supplements is due to the properties of its constituent ingredients. The amino acid cystine is essential for normal hair and nail growth. Vitamins-antioxidants A, C, E increase the body’s resistance to the negative effects of the environment and slow down the aging process. Beta-carotene and vitamin A help maintain normal blood circulation in the skin and increase its firmness and elasticity. Biotin prevents dandruff, enhances subcutaneous circulation, participates in the synthesis of keratin, helps to absorb proteins, fats and carbohydrates, affects the production of collagen ⁹ .

Contraindications : age under 18, individual intolerance to components, overdose of vitamins A and D. During pregnancy, this dietary supplement should not be taken together with other drugs that contain vitamin A.

Famvital

This dietary supplement contains components supporting healthy skin, hair and nails, as well as improving overall well-being. Green tea and grape seed extracts in the composition have an antioxidant effect and protect cells from damage by free radicals. Omega-3 polyunsaturated fatty acids, selenium, zinc and vitamin C restore and nourish the skin from the inside, increase its elasticity. The dietary supplement is recommended for women over 35 years old, in whose body the aging process begins ¹⁰ .

Contraindications : under 18 years of age, pregnancy and lactation.

How to choose vitamins for psoriasis

Today, there are many complex vitamin preparations that will help strengthen systemic and local immunity, accelerate skin healing, and improve all types of metabolism.

When prescribing vitamins to a patient suffering from psoriasis, the doctor must take into account not only the degree of skin damage and the stage of the disease, but also age, gender, the state of the liver, kidneys and the presence of other concomitant diseases.

In severe cases of psoriasis, vitamins can be injected. With a mild course, vitamins are prescribed in tablets, drops and capsules.

Doctors’ Testimonials

Many doctors agree that nutritional supplements cannot cure psoriasis on their own. However, supplementation with zinc, magnesium, vitamin B6, and the antioxidant vitamins A, C, and E may be beneficial for people with psoriasis, as it helps relieve dry skin and improve metabolism. Also, the effect of fish oil rich in unsaturated fatty acids on the skin condition in psoriasis is currently being studied.

Popular questions and answers

Why psoriasis occurs, what vitamins can reduce its manifestations, and other popular questions are answered by dermatologist Regina Kuznetsova .

Why does psoriasis occur?

– Psoriasis is a chronic inflammatory skin autoimmune disease. The exact cause of this disease is unknown. There are several theories of the origin of psoriasis:

• autoimmune theory – the immune system fails, causing immune cells to attack keratinocytes (skin cells). This provokes inflammation and tissue damage.
• exchange theory – due to the acceleration of metabolism in the body, a large number of free radicals and toxins appear. Hence the inflammatory reaction in the dermis.
• genetic theory – identified genes predisposing to psoriasis. This hypothesis is recognized by the largest number of doctors.
• infectious theory – dermatologists note that any acute infectious process (especially of viral origin) or the presence of a permanent focus of infection can provoke relapses of psoriasis. Many patients with psoriasis become ill after suffering a streptococcal infection (for example, tonsillitis).
• endocrine theory – in patients with psoriasis, dysfunctions of the thyroid gland, adrenal glands, and pituitary gland are often detected.
• neurogenic theory – prolonged stress, neuropsychic overload, changes in the autonomic nervous system can cause the development of psoriasis. All these factors cause an imbalance in the endocrine system, a violation of metabolic and immunological processes.

If the cause of psoriasis had become known, then a medicine would have been synthesized long ago and a treatment regimen working at all stages of the disease would have been created.

How can vitamins help with psoriasis?

– Vitamin therapy for psoriasis is very important. Vitamins improve blood circulation, cell and tissue metabolism, reduce inflammation, and help damaged skin recover faster.

The doctor prescribed a psoriasis treatment regimen. Can drug addiction develop?

– In the treatment of psoriasis, there may be an “addiction” of the body to any therapy. In this case, it is necessary to quickly change the tactics of treatment. It is important to remember that in addition to medication, lifestyle plays an important role in the treatment of psoriasis. You should avoid stress, stop drinking alcohol and smoking, follow the diet prescribed by your doctor.

How to take vitamins for psoriasis

– Vitamins for psoriasis are taken with meals or 5-10 minutes after. The dosage is determined in the instructions for a particular drug.

The duration of the treatment course of vitamins for psoriasis is set by the doctor and averages 2 months. The daily amount of the drug can be reduced or increased, on the recommendation of the attending doctor.

Photo: market.yandex.ru, KP

Sources:

1. Clinical pharmacology. 2018 year. Analogues of vitamin D3 in the treatment of patients with psoriasis. I. V. Petrova, R. M. Radzhabov, A. R. Abdulov, M. G. Manatov, R. I. Glushakov, S. N. Proshin https://cyberleninka.ru/article/n/analogi-vitamina -d3-v-terapii-bolnyh-psoriazom/viewer
2. Pentovit. Instructions for use. https://grls.rosminzdrav.ru/Grls_View_v2.aspx?routingGuid=a80b38bd-d9d2-41fe-a7cb-8abf55c7126f
3. Aevit. Manufacturer’s instructions https://tulapharm.com/storage/files/54278d7cd6852f531d31e2877e03ec368d144cf3-I5MFkdN.pdf
4. Vitamin E. Instructions for use. https://grls.rosminzdrav.ru/Grls_View_v2.aspx?routingGuid=84994d76-28ff-4998-b1bf-02e4fe52ae0f
5. Experience in the use of beta-carotene solution in combination with vitamin E in the complex therapy of psoriasis. 2011 https://www.mediasphera.ru/issues/klinicheskaya-dermatologiya-i-venerologiya/2011/6/031997-2849201168
6. Losterin.