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What can a pap smear tell: What Does a Pap Test Detect?

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What Does a Pap Test Detect?


Updated November 2022

Its real name: Papanicolaou test. There’s a good chance you know it as a Pap smear, or more appropriately, a Pap test. Discover the science behind this test ­— including what it doesn’t detect.

The Science Behind the Test

A Pap test is when a clinician takes a sample of cells from your cervix (the lower part of the uterus neck located at the top of the vagina). Then, they put the cells into small jar with a special liquid to preserve the sample so it can be tested for abnormalities under a microscope.

There are many reasons why you may have abnormal findings, such as:

  • Mild inflammation
  • Human papillomavirus (HPV)
  • Cancer or precancer

Cervical cancer, if caught early, is highly treatable.

— Melissa A. Simon, MD

“The Pap test can detect changes in cells that could be concerning for possible cervical cancer or precancerous changes,” says Melissa A. Simon, MD, an obstetrician and gynecologist at Northwestern Medicine. 

Abnormal test results will indicate a number of atypical squamous cells, which will then be classified as low-grade or high-grade squamous intraepithelial lesions (LSIL and HSIL, respectively). LSIL indicates that the changes are mildly abnormal and usually caused by HPV infection, and they may go away on their own. HSIL suggests more serious changes.

“Cells that are determined to be atypical of undetermined significance basically reveal slightly abnormal cells, and it does not clearly mean precancer is there. Usually, these test results indicate to follow up in a year,” says Dr. Simon.

Abnormal Pap test results are typically caused by HPV. HPV is a sexually transmitted infection (STI) that enters cells and changes them. HPV can be prevented by getting the vaccine, which targets the HPV types that most commonly cause certain types of cancer and genital warts. Certain high-risk types of HPV are associated with an increased risk for the following types of cancer:

  • Cervical
  • Vulva
  • Vagina
  • Penis
  • Anus
  • Mouth and throat cancer

Depending on your Pap test results, your physician will determine the appropriate next steps. This can include another test, known as a colposcopy, which uses a special camera to look at your cervix. During this procedure, a biopsy of cells on your cervix may be taken for further analysis. Your physician may also opt for a loop electrosurgical excision procedure, known as LEEP, if there are more concerning findings or repeated abnormal Pap test results. A LEEP removes part of your cervix tissue for diagnosis and/or treatment.

What It Can’t Determine

Although Pap tests can help detect precancerous cells on the cervix, there are other types of gynecologic cancers that Pap tests cannot detect. 

Because your ovaries are far away from your cervix, it is extremely unlikely that a Pap test will  detect ovarian cancer. For that to happen, the cancer cells would have to travel away from your ovaries, through your fallopian tubes and uterus, and into the area surrounding your cervix.

The Pap test is also limited in detecting other types of STIs. If you are concerned you may have a STI, you should ask your clinician to screen for specific STIs.

Pap Tests Are Part of Routine Screening

The U.S. Preventive Services Task Force (USPSTF) and the American College of Obstetricians and Gynecologists (ACOG) both suggest starting screening at age 21. However, the American Cancer Society suggests that cervical cancer screening begin at age 25.

Dr. Simon explains that there are many nuances and complexities of when to start screening and how frequently screening should be done. Cervical cancer can also take a long time to develop, which could explain the varying guidelines.

Screening with a Pap test every three years during this time period is acceptable. However, other types of screening include primary HPV testing every five years. If primary HPV testing is not available, screening may be performed with co-testing that combines an HPV test with a Pap test every five years.

“If you have vaginal discharge, abnormal bleeding or are feeling pain, schedule a visit with your healthcare clinician to discuss these symptoms,” says Dr. Simon. “It’s important that if you are ever in any doubt of what you are feeling or experiencing, and are questioning if you need screening or a test, always reach out to your care team so you can have that conversation.”

The USPSTF, ACOG and American Cancer Society agree that people older than 65 do not need to be screened if adequate prior screening has been completed with normal results and if there is no history or high risk of cervical cancer. Dr. Simon recommends talking to your primary care clinician about your individual risks and recommendations for screening.

Bottom Line

The Pap test is a screening tool that can help detect abnormal cells on your cervix. This early detection can be important in stopping precancerous cells from progressing to cervical cancer.  

“Cervical cancer, if caught early, is highly treatable. And that’s why engaging in routine screening is very important,” says Dr. Simon. “Between the HPV vaccine and routine testing, this type of cancer really should be nonexistent.

What Should I Know About Cervical Cancer Screening?

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“If I didn’t go to that appointment, I might not be around for my kids,” says Cindy. Her cervical cancer screening test found precancerous cells. She shares her story in this video.

The HPV test and the Pap test can help prevent cervical cancer or find it early.

  • The HPV test looks for the virus (human papillomavirus) that can cause cell changes on the cervix.
  • The Pap test (or Pap smear) looks for precancers, cell changes on the cervix that might become cervical cancer if they are not treated appropriately.

Both tests can be done in a doctor’s office or clinic. During the Pap test, the doctor will use a plastic or metal instrument, called a speculum, to look inside your vagina. This helps the doctor examine the vagina and the cervix, and collect a few cells and mucus from the cervix and the area around it. The cells are sent to a laboratory.

  • If you are getting a Pap test, the cells will be checked to see if they look normal.
  • If you are getting an HPV test, the cells will be tested for HPV.

What is cervical precancer? When there are cervical cells that look abnormal but are not yet cancerous, it is called cervical precancer. These abnormal cells may be the first sign of cancer that develops years later. Cervical precancer usually doesn’t cause pain or other symptoms. It is found with a pelvic exam or a Pap test.

If you have a low income or do not have health insurance, you may be able to get a free or low-cost screening test through the National Breast and Cervical Cancer Early Detection Program.

Find out if you qualify

When to Get Screened

If You Are 21 to 29 Years Old

You should start getting Pap tests at age 21. If your Pap test result is normal, your doctor may tell you that you can wait three years until your next Pap test.

If You Are 30 to 65 Years Old

Talk to your doctor about which testing option is right for you—

  • An HPV test only. This is called primary HPV testing. If your result is normal, your doctor may tell you that you can wait five years until your next screening test.
  • An HPV test along with the Pap test. This is called co-testing. If both of your results are normal, your doctor may tell you that you can wait five years until your next screening test.
  • A Pap test only. If your result is normal, your doctor may tell you that you can wait three years until your next Pap test.

If You Are Older Than 65

Your doctor may tell you that you don’t need to be screened anymore if—

  • You have had normal screening test results for several years, and
  • You have not had a cervical precancer in the past, or
  • You have had your cervix removed as part of a total hysterectomy for non-cancerous conditions, like fibroids.

No special preparation is needed before you have an HPV test.

If you are getting a Pap test, you can take steps to make sure the test results are accurate. Avoid intercourse, douching, and using vaginal medicines or spermicidal foam for 2 days before the test. If you had sex before the test, go to the appointment as planned and let the doctor know.

If you have your period, don’t worry. Both tests can still be done at this time.

Test Results

It can take as long as three weeks to receive your test results. If your test shows that something might not be normal, your doctor will contact you and figure out how best to follow up. There are many reasons why test results might not be normal. It usually does not mean you have cancer.

If your test results show cells that are not normal and may become cancer, your doctor will let you know if you need to be treated. In most cases, treatment prevents cervical cancer from developing. It is important to follow up with your doctor right away to learn more about your test results and receive any treatment that may be needed.

If your test results are normal, your chance of getting cervical cancer in the next few years is very low. Your doctor may tell you that you can wait several years for your next cervical cancer screening test. But you should still go to the doctor regularly for a checkup.

how to pass the test and what the result indicates

Content

  • 1 Throat and nose swab analysis: what information can be obtained?
    • 1.1 How to do a nose and throat swab test?
      • 1.1.1 Choose the right time for analysis
      • 1.1.2 The quality of a smear depends on the correct preparation of the procedure
      • 1.1.3 You should only take a smear in accredited laboratories
      • 1.1.4 Get the result of the analysis in a few days
      • 1.1.5 Don’t forget to take tests in time
    • 1.2 Preparing for a nasal and throat swab test
      • 1.2.1 How to properly prepare for a test?
      • 1.2.2 How to take a smear?
      • 1.2.3 How to properly store the sample for analysis?
    • 1.3 How is the nose or throat swab sample taken?
    • 1. 5 Nasal and throat swab results
    • 1.6 How to correctly interpret nasal and throat swab results
      • 1.6.1 Positive result
      • 1.6.2 Negative result
      • 1.6.3 False negative result
      • 1.6.4 Key indicators
    • 1.7 What the test result says nasal and throat swab for infection
    • 1.8 What organisms can be found in a nasal and throat swab test?
    • 1.9 How to Diagnose Respiratory Diseases Using Nasal and Throat Swabs
    • 1.10 Timing of nasal and throat swab results
    • 1.11 How to use nasal and throat swab results to prevent the spread of infections
    • 1.12 Related videos:
    • 1.13 Q&A:
      • 9 0004
      • 1.13.0.1 What training need to be done before the delivery of a smear from the nose and pharynx?
      • 1.13.0.2 How to take a swab from the nose and throat?
      • 1.13.0.3 How long do I have to wait for test results?
      • 1.13.0.4 Why is a nasal and throat swab analysis necessary?
      • 1. 13.0.5 Is it possible to have a nasal and pharyngeal swab analyzed at a polyclinic or do I need to look for a specialized laboratory?
      • 1.13.0.6 How to interpret the results of a nasal and throat swab?

Find out when and why throat and nose swabs are done, what tests are done, and how to properly prepare for the test. Take care of your health in advance!

Nasal and pharyngeal swab analysis is an important diagnostic tool for detecting respiratory infections. It is performed by taking a sample of the mucous membrane, which is then examined in the laboratory. Proper preparation for analysis and proper collection and storage of the sample are the key to the reliability of the results.

A nasal and throat swab may indicate the cause of symptoms such as runny nose, cough, nasal congestion or difficulty breathing. It is used to detect bacteria and viruses that may be responsible for acute or chronic respiratory tract infections. The results of the smear analysis can help the doctor determine the correct treatment and recommendations for the patient.

In this article, we will tell you how to properly take a swab from the nose and throat, which microorganisms can be detected in the analysis and how to interpret the results of their presence or absence.

How to pass a nose and throat swab test?

Choose the right time for the test

Before taking the test, you must stop taking medication for the next few days. You should also avoid taking antibiotics as they can skew the test results. It is best to analyze smears in the morning and on an empty stomach.

The quality of a smear depends on the correct preparation of the procedure

Before taking a smear, the nose and throat must be cleared of mucus and other contaminants. To get a good result, you must take the procedure seriously and follow all the instructions.

Pap smears should only be taken at accredited laboratories

For accurate results, it is recommended that you contact only professional medical laboratories. There you will be sure that you are using high-quality equipment, and the results will be correct.

Get test results in a few days

Test results are usually available after a few days. If the result shows an infection, the doctor may suggest testing family contacts to avoid further spread of the disease.

Do not forget to take tests in time

Tests should be taken regularly according to the following recommendations: at the first symptoms of a runny nose and a runny nose with purulent drainage, with influenza, tonsillitis, sinusitis, bronchitis, as well as with Colorado fever, tuberculosis and chancroid.

Preparing for a nose and throat swab test

How to prepare for a test?

Do not eat or drink for 2-3 hours before taking a nose and throat swab. It is also not recommended to use drops and nasal sprays, as they can distort the results of the analysis.

Before the procedure, blow your nose well and cough up the mucus from your throat. This will help you get a cleaner sample for analysis.

How to take a smear?

To take a swab from the nose, tilt your head back and place a small cotton swab about 2 cm deep in each nostril. You need to gently rotate the swab around the axis to collect the mucus, and then carefully remove it. Similarly, it is necessary to make a smear from the posterior pharyngeal wall through the open mouth.

How to properly store a sample for analysis?

The resulting nasal and pharyngeal swab should be placed in a special tube with transport medium and capped. The sample must be delivered to the laboratory as soon as possible in order for the analysis results to be as accurate as possible.

How a nose or throat swab is performed

A nose or throat swab is a routine procedure in the clinic to identify the causative agent of an infectious disease. The procedure begins with the fact that the medical professional carefully processes the area of ​​​​the nose or pharynx to prevent the entry of foreign microflora.

After taking the swab sample, the health worker places it in a special container tube for shipment to the laboratory. In the laboratory, the smear is processed and studied in detail to identify the causative agent of the infection.

Pap smears are usually not painful, but may cause discomfort. Therefore, if the patient is anxious or afraid of the procedure, it is worth discussing with the healthcare professional the possibility of using analgesics or painkillers to make the swab more comfortable.

Where can I have my nose and throat swab tested?

To have a nasal and pharyngeal swab test, you must contact the laboratory of a medical institution.

Most public clinics have laboratories where you can get tested free of charge. You must first make an appointment with an otolaryngologist to receive a referral for analysis.

You can also get tested at private medical centers. Services are provided here both on a paid basis and on a free basis (within the framework of compulsory medical insurance).

For an untimely test, you can contact the mobile laboratories. They carry out home visits to the patient, bypassing the need to worry about free time, visits to the medical center and waiting for long lines on the spot.

It is important to pay attention to the qualifications of the medical staff, the equipment used and the positive feedback from patients when choosing a clinic or medical center for a nasal and pharyngeal swab test.

Nasal and throat swab results

After the smear is submitted to the laboratory, at least one working day passes, during which the sample is examined for the presence of various infections, bacteria and viruses. The results of the analysis are delivered to the doctor, who first checks for the presence of pathogens in the sample.

The analysis may indicate specific types of bacteria or viruses found in the swab specimen. This allows the doctor to more accurately determine the treatment and be sure to prevent the transmission of infection to others.

  • Positive – infection detected in the swab specimen
  • Negative – infection not detected in the swab specimen are only one of many diagnostic tools and cannot be used as the sole criterion in making a diagnosis.

    How to correctly interpret nasal and throat swab results

    Positive result

    A positive nasal and throat swab result indicates an infection in the patient. In this case, the doctor may prescribe additional studies to determine the type of infection and select the appropriate treatment. It is very important to start treatment on time to prevent the development of complications.

    Negative result

    A negative nasal and throat swab result means that there is no infection in the patient’s body. However, if symptoms continue or worsen, a second test may be necessary, as it is possible that the infection has not yet become clear enough to be detected.

    False negative result

    There is also such a thing as false negative result . This means that the analysis of a swab from the nose and throat did not detect an infection, although it is present in the patient’s body. This situation can occur if the sample is not taken at the right time, when the concentration of the virus or bacteria in the body is the highest. In this case, the doctor may recommend a repeat test or another type of test to confirm the presence of an infection.

    Key metrics

    Nasal and throat swab results may contain several key metrics such as bacterial count, bacterial species, antibiotic susceptibility, and more. The doctor can use this data to establish an accurate diagnosis and select the most effective treatment. However, these results must be interpreted by the physician as they may be too complex or confusing for the patient.

    What a nasal and throat swab test says about infection

    Diseases of the respiratory system can lead to disruption of the normal functioning of the body. To identify the causative agent of inflammatory processes in the nose and throat, a microbiological examination of a smear of the mucous membrane is carried out.

    Infections are often caused by different types of viruses. Among these most common viral infections are the flu, the common cold, and other respiratory viruses.

    Nasal and throat swab results may also indicate a bacterial infection. It can cause severe damage to the general condition of the body, and some types of bacteria can cause dangerous complications. Some of these bacteria can be treated with antibiotics.

    In any case, the result of the analysis of a swab from the nose and throat is an indispensable element in the diagnosis of respiratory diseases and allows you to choose the most effective method of treating infections.

    Which organisms can be detected by nasal and throat swab analysis?

    Nasal and throat swab to detect the presence of microorganisms that can lead to the development of an infectious disease in humans. As a result of the analysis, various bacteria and viruses can be detected.

    Bacteria that can be detected by nasal and throat swab analysis often include pneumococci, staphylococci, streptococci, Haemophilus influenzae, and meningococci.

    Viruses that can be detected by nasal and throat swabs can cause illnesses such as influenza, coronavirus, respiratory syncytial infection, and other viral infections of the upper respiratory tract.

    Nose and throat swabs can also detect fungi that can cause various infections such as candidiasis and aspergillosis.

    It is important to note that the results of the analysis of a swab from the nose and throat can be different and depend on the method of examination. When taking the test, you must follow the recommendations of the doctor and laboratory in order to obtain the most accurate results.

    How to Diagnose Respiratory Diseases Using a Nasal and Throat Swab Test

    A nasal and throat swab test can identify the causative agent of a respiratory tract infection. Typically, these are microorganisms such as bacteria or viruses. The results of the analysis can indicate the presence of an infection and help in choosing the best treatment.

    To correctly diagnose respiratory diseases based on the results of a smear test, you need:

    1. Find out which microorganism has caused the disease.
    2. Determine the sensitivity of a microorganism to antibiotics.

    These data will help you choose the most effective drug for the treatment of the disease. Also, the results of the analysis can help determine the degree of infection and show how quickly the disease progresses.

    It is important to remember that for an accurate diagnosis, you must follow all the methodological rules when taking a swab from the nose and throat, as well as follow the doctor’s recommendations regarding preparation for the analysis.

    The timing of the results of the nasal and throat swab

    The timing of the results of the analysis of the nose and throat swab depends on the chosen method of examination. On average, the result can be ready in a few days or a week.

    If pathological microorganisms are found, treatment is prescribed according to their sensitivity to antibiotics. In this case, the result of a swab from the nose and throat plays an important role in choosing the optimal treatment.

    To obtain accurate results, it is important to properly prepare for the analysis and follow all the doctor’s recommendations. It is necessary to first refuse to take antibiotics and sulfonamides, stop using nasal drops and sprays 3 days before taking a smear, and also avoid contact with patients with fever and other signs of an infectious disease.

    How to use nasal and throat swab results to prevent the spread of infections

    After receiving the results of the analysis of the swab from the nose and throat, it is necessary to discuss them with the doctor. The doctor will be able to determine the presence or absence of pathogenic microflora and recommend the necessary therapy. Your doctor may also recommend that you wear a mask and isolate yourself from other people until the infection is completely gone to prevent it from spreading.

    In addition, it is important to observe the rules of personal hygiene in order not to infect other people. It is necessary to frequently wash hands with soap or use an antiseptic, do not separate personal belongings and focus on general safety principles. If only one member of the family is sick, they should use separate dishes, towels, toothbrushes, etc. It is necessary to regularly ventilate the room, clean and disinfect surfaces that may be contaminated with germs.

    • Wash hands regularly;
    • Do not separate personal items;
    • Use separate dishes, towels, toothbrushes, etc.;
    • Ventilate the room regularly;
    • Clean and disinfect surfaces;

    By following these simple rules, you can prevent the spread of infection and protect yourself and others from possible infection.

    Video on the topic:

    Q&A:

    What preparation should be done before taking a swab from the nose and pharynx?

    Before taking the test, you must refrain from eating, drinking and smoking for 2-3 hours. It is also not recommended to use vasoconstrictor drops 24 hours before the test.

    How to take a swab from the nose and throat?

    To take a smear, a special brush or cotton wool is used, which must be carefully removed from the mucous membrane of the nose and throat. It is not recommended to deeply insert a brush or cotton wool into the nose or throat, so as not to damage the mucous membrane.

    How long do I have to wait for test results?

    The waiting time for results may vary depending on the laboratory and type of analysis. On average, results are ready in 3-5 days

    Why do you need a nasal and throat swab test?

    Nasal and pharyngeal swabs can detect infections in the respiratory tract, including viral and bacterial infections. Also, this analysis can be used to detect allergic reactions to certain substances.

    Is it possible to have a nasal and pharyngeal swab analyzed at a polyclinic or do I need to look for a specialized laboratory?

    Nasal and pharyngeal swab analysis can be done both in the outpatient clinic and in specialized laboratories. However, it is important to ensure that the laboratory has the necessary equipment and certification to perform this analysis.

    How do I interpret the results of a nasal and throat swab test?

    Nose and throat swab results should only be interpreted by a qualified physician, depending on the type of test and the presence of infections or allergic reactions. It is important to seek the advice of a specialist doctor who can explain the results and prescribe the necessary treatment in the presence of pathologies.

    Smear for ENT flora in St. Petersburg

    Smear for ENT flora is performed for inflammatory pathologies of the nose, pharynx, ear and recurrent infections. As a result of a smear examination, pathogenic microorganisms and yeast fungi can be detected in the mucous membranes of the paranasal sinuses, pharynx, larynx, and external auditory canals. After finding out which microorganisms caused the disease, and determining the sensitivity of microbes to antibiotics, certain drugs are prescribed that will eliminate the infection.

    Medical Specialists

    Vlasov Anton Vasilyevich

    Otorhinolaryngologist

    Saranchin Alexander Sergeevich

    Otorhinolaryngologist

    Gindryuk Aida Fataliyevna

    Otorhinolaryngologist

    Currently, the site is working to change the price list, please check the current information by phone: 640-55-25 or leave a request, the operator will contact you.

    Prices for services

    • Obtaining swabs from the mucous membrane of the oropharynx
      330a

    • Obtaining smears from the mucous membrane of the nasopharynx
      330a

    • Obtaining swabs from the upper respiratory tract
      400a

    The information and prices presented on the site are for reference only and are not a public offer.

    Our clinics in St. Petersburg

    For more information and to make an appointment, please call
    +7 (812) 640-55-25

    Make an appointment

    An ENT smear is taken when passing trade union commissions for work related to the food industry, children, seriously ill people, in order to prevent the risk of infection with Staphylococcus aureus. An indication for taking a smear from the ENT organs is an examination of pregnant women immediately before hospitalization in the maternity hospital, which makes it possible to identify microorganisms that can complicate the course of pregnancy or cause an infectious disease. In children, a smear is performed before entering preschool groups, as well as with chronic tonsillitis, adenoiditis, and all types of sinusitis. A smear from the ENT organs is also taken from people who have been in contact with patients with infectious diseases in order to prevent infection.

    A swab is taken from the mucous membrane of the nose, pharynx or external auditory canal with a sterile swab, applied to a glass slide and sent to the laboratory for examination. Sowing is prepared for about 10 days, until all microorganisms grow on a special nutrient medium.

    Smearing is performed in both adults and children and makes it possible to identify and cure acute or chronic tonsillitis, diphtheria, sinusitis, otitis media, and other diseases.

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    During the ultrasound examination, the doctor explained everything, told and even clearly showed. Initially, I came to her for the GHA procedure, the doctor did a wonderful job, nothing hurt, reassured me (I’m still that coward) … based on the GHA, she gave her recommendations Correct. Thank you very much!
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    I want to express my deep gratitude to the therapist Dereshovsky Alexander Sergeevich.
    At the 28th week of pregnancy, this infection called COVID-19 did not bypass us. On the day the doctor was called, Alexander Sergeevich came, looked, listened, took smears for covid, prescribed competent treatment. And most importantly, he was always in touch with me, both in the morning, and in the afternoon, and in the evening.
    The infection has receded.
    Thank you, Alexander Sergeevich, for your work in such a difficult time for everyone.
    Health to you and your loved ones!????

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    I, Saibel Olga Evgenievna, born on 04/05/1976, I earnestly ask you to reward all doctors, junior medical staff and administrators of the clinic LLC Medicenter YuZ, Murino, Okhtinskaya alley, d. 18, for a huge contribution to saving my life.
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    Good afternoon everyone, I want to express my gratitude to the neurologist Irina Bratanova. He came to the appointment with a paralysis of the facial nerve, the left side of his face was practically paralyzed. As it turned out, acupuncture quite successfully treats such diseases, after a couple of sessions changes for the better were noticeable, and on the 8th-9th everything returned to normal, I consider this not only my merit, but also the doctor :). By the way, the prices for IRT in the region are quite moderate, and the clinic at 6 Polikarpova Street made a good impression.

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    good afternoon! I want to sincerely thank the gastroenterologist Bannikova Tatyana Petrovna for the professional reception. I came in with pain, thinking that I had a problem with the gallbladder, even took the appropriate medication, but after questioning the symptoms and examination, I was given a different diagnosis and prescribed the appropriate treatment. Very kind and caring doctor! Thank you!
    Your name: Valentina
    Event Date: April 25
    Specialization of the doctor: Gastroenterologist Bannikova T.P.
    Examination: initial appointment with complaints of pain in the side.