What is mag oxide used for. Magnesium Oxide: Uses, Dosage, Side Effects, and Precautions
What are the primary uses of magnesium oxide. How should it be taken for different conditions. What are the potential side effects and precautions to consider. How does magnesium oxide function in the body.
Understanding Magnesium Oxide: An Essential Mineral Supplement
Magnesium oxide is a versatile compound that plays a crucial role in various bodily functions. It’s a combination of magnesium and oxygen, forming a white, powdery substance that’s widely used in medicine and dietary supplements. But what exactly makes this compound so important?
Magnesium is an essential mineral that our bodies need for numerous processes, including muscle and nerve function, energy production, and bone health. Magnesium oxide serves as a convenient way to supplement this vital nutrient when dietary intake is insufficient.
The Importance of Magnesium in the Body
Magnesium plays a role in over 300 enzymatic reactions in the human body. It’s involved in:
- Energy production
- Protein synthesis
- Muscle and nerve function
- Blood glucose control
- Blood pressure regulation
- Bone development
Given its widespread involvement in bodily functions, maintaining adequate magnesium levels is crucial for overall health and well-being.
Primary Uses of Magnesium Oxide in Healthcare
Magnesium oxide is a multifaceted compound with several medical applications. Its versatility makes it a valuable tool in addressing various health concerns. Here are the primary uses of magnesium oxide in healthcare:
1. As an Antacid
One of the most common uses of magnesium oxide is as an antacid. It works by neutralizing stomach acid, providing relief from:
- Heartburn
- Sour stomach
- Acid indigestion
The compound’s ability to increase the pH of the stomach makes it an effective over-the-counter solution for these common digestive issues.
2. As a Laxative
Magnesium oxide also functions as a laxative, promoting bowel movements by drawing water into the intestines. This property makes it useful for:
- Short-term relief of constipation
- Bowel preparation before medical procedures
However, it’s important to note that magnesium oxide should not be used as a long-term solution for chronic constipation without medical supervision.
3. As a Dietary Supplement
When dietary intake of magnesium is insufficient, magnesium oxide can serve as a supplement to help maintain proper magnesium levels in the body. This can be particularly beneficial for individuals with:
- Magnesium deficiency
- Certain medical conditions that affect magnesium absorption
- Diets low in magnesium-rich foods
Supplementation can help prevent the negative health effects associated with magnesium deficiency.
Proper Dosage and Administration of Magnesium Oxide
The correct dosage of magnesium oxide can vary depending on the intended use and individual factors. How should one take magnesium oxide to ensure its effectiveness and safety?
For general supplementation, magnesium oxide is typically taken orally in tablet or capsule form. The frequency of dosing can range from once to four times daily, depending on the specific product and the condition being treated. It’s crucial to follow the directions on the package or prescription label carefully.
Dosage Guidelines
While specific dosages should be determined by a healthcare provider, here are some general guidelines:
- As an antacid: 400-800 mg up to four times daily
- As a laxative: 2-4 tablets (400-800 mg) with a full glass of water
- For magnesium supplementation: 250-500 mg daily
Remember, these are general guidelines and individual needs may vary. Always consult with a healthcare professional for personalized dosage recommendations.
Administration Tips
To maximize the effectiveness of magnesium oxide and minimize potential side effects:
- Take with a full glass of water or juice
- If used as a laxative, take on an empty stomach
- Space doses of magnesium oxide at least 2 hours apart from other medications
- Do not exceed the recommended dosage without medical advice
Proper administration ensures optimal absorption and reduces the risk of adverse effects.
Potential Side Effects and Precautions of Magnesium Oxide
While magnesium oxide is generally safe when used as directed, it can cause side effects in some individuals. What are the potential adverse reactions one should be aware of when taking this supplement?
Common side effects of magnesium oxide include:
- Diarrhea
- Stomach cramps
- Nausea
These symptoms are usually mild and often resolve on their own. However, if they persist or worsen, it’s important to consult a healthcare provider.
Serious Side Effects
In rare cases, more serious side effects may occur. Seek immediate medical attention if you experience:
- Allergic reactions (rash, itching, swelling)
- Dizziness or lightheadedness
- Mood or mental changes
- Unusual tiredness or weakness
- Severe nausea or vomiting
These symptoms may indicate an adverse reaction or magnesium toxicity.
Precautions and Contraindications
Certain individuals should exercise caution or avoid magnesium oxide altogether. These include people with:
- Kidney disease
- Heart conditions
- Intestinal disorders
- Scheduled surgeries
Additionally, magnesium oxide can interact with various medications, including antibiotics, bisphosphonates, and certain heart medications. Always inform your healthcare provider about all medications and supplements you’re taking before starting magnesium oxide.
Interactions and Considerations with Magnesium Oxide
Magnesium oxide can interact with various substances, potentially affecting its efficacy or causing adverse effects. What should individuals be aware of when taking this supplement alongside other medications or dietary components?
Drug Interactions
Magnesium oxide can interact with several types of medications:
- Antibiotics: Magnesium can reduce the absorption of certain antibiotics, such as tetracyclines and fluoroquinolones
- Bisphosphonates: Used to treat osteoporosis, these drugs may have reduced absorption when taken with magnesium
- Diuretics: Some diuretics can increase magnesium excretion, while others can cause magnesium retention
- Anticoagulants: Magnesium may enhance the effects of blood thinners like warfarin
To avoid these interactions, it’s recommended to take magnesium oxide at least 2 hours before or after other medications.
Dietary Considerations
Certain dietary factors can affect magnesium absorption and utilization:
- High-fiber diets may decrease magnesium absorption
- Phytic acid, found in whole grains and legumes, can bind to magnesium and reduce its absorption
- High intake of calcium or iron may compete with magnesium for absorption
Balancing these dietary factors can help optimize magnesium absorption and effectiveness.
Storage and Disposal of Magnesium Oxide
Proper storage and disposal of magnesium oxide are crucial for maintaining its efficacy and ensuring safety. How should this supplement be stored, and what’s the best way to dispose of unused medication?
Storage Guidelines
To maintain the quality and effectiveness of magnesium oxide:
- Keep in its original container, tightly closed
- Store at room temperature, away from excess heat and moisture
- Avoid storing in the bathroom, where humidity levels can be high
- Keep out of reach of children and pets
Following these guidelines helps preserve the supplement’s potency and prevents accidental ingestion.
Proper Disposal Methods
When it comes to disposing of unused or expired magnesium oxide:
- Do not flush down the toilet or pour down the drain
- Utilize medicine take-back programs when available
- If take-back programs are not accessible, mix with an undesirable substance (like used coffee grounds), seal in a plastic bag, and dispose in household trash
These methods help prevent environmental contamination and reduce the risk of accidental consumption by others.
The Role of Magnesium Oxide in Overall Health and Wellness
Beyond its specific medical uses, magnesium oxide plays a significant role in maintaining overall health and wellness. How does this supplement contribute to various aspects of bodily function and general well-being?
Cardiovascular Health
Magnesium is crucial for heart health:
- Helps regulate heart rhythm
- Supports healthy blood pressure levels
- May reduce the risk of cardiovascular diseases
Adequate magnesium levels are associated with a lower risk of hypertension and heart disease.
Bone Health
Magnesium is essential for maintaining strong bones:
- Aids in the absorption and metabolism of calcium
- Activates vitamin D, which is crucial for calcium absorption
- Supports bone density and strength
Sufficient magnesium intake may help prevent osteoporosis and fractures, especially in older adults.
Mental Health and Cognitive Function
Magnesium plays a role in brain health and mental well-being:
- Supports neurotransmitter function
- May help alleviate symptoms of depression and anxiety
- Potentially improves sleep quality
Some studies suggest that magnesium supplementation could have positive effects on mood and cognitive function.
Metabolic Health
Magnesium is involved in glucose metabolism and insulin sensitivity:
- Helps regulate blood sugar levels
- May reduce the risk of type 2 diabetes
- Supports overall metabolic health
Maintaining adequate magnesium levels can contribute to better metabolic function and potentially reduce the risk of metabolic disorders.
In conclusion, magnesium oxide is a versatile and important supplement that can contribute to various aspects of health and wellness. From its specific medical uses as an antacid and laxative to its broader role in supporting cardiovascular, bone, mental, and metabolic health, magnesium oxide offers numerous potential benefits. However, as with any supplement, it’s crucial to use it appropriately, be aware of potential side effects and interactions, and consult with healthcare professionals for personalized advice. By understanding the proper use, storage, and disposal of magnesium oxide, individuals can safely harness its benefits and support their overall health and well-being.
Magnesium Oxide: MedlinePlus Drug Information
pronounced as (mag nee’ zee um) (ox’ ide)
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Magnesium is an element your body needs to function normally. Magnesium oxide may be used for different reasons. Some people use it as an antacid to relieve heartburn, sour stomach, or acid indigestion. Magnesium oxide also may be used as a laxative for short-term, rapid emptying of the bowel (before surgery, for example). It should not be used repeatedly. Magnesium oxide also is used as a dietary supplement when the amount of magnesium in the diet is not enough. Magnesium oxide is available without a prescription.
Magnesium oxide comes as a tablet and capsule to take by mouth. It usually is taken one to four times daily depending on which brand is used and what condition you have. Follow the directions on the package or on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take magnesium oxide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Take any other medicine and magnesium oxide at least 2 hours apart.
If you are using magnesium oxide as a laxative, take it with a full glass (8 ounces [240 milliliters]) of cold water or fruit juice. Do not take a dose late in the day on an empty stomach.
Do not take magnesium oxide as an antacid for longer than 2 weeks unless your doctor tells you to. Do not take magnesium oxide as a laxative for more than 1 week unless your doctor tells you to.
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
Before taking magnesium oxide,
- tell your doctor and pharmacist if you are allergic to magnesium oxide, other antacids or laxatives, or any other drugs.
- tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other antacids or laxatives, anticoagulants (‘blood thinners’) such as warfarin (Coumadin), aspirin, diuretics (‘water pills’), medicine for ulcers (cimetidine [Tagamet], ranitidine [Zantac]), and vitamins.
- tell your doctor if you have or have ever had heart, kidney, liver, or intestinal disease or high blood pressure.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking magnesium oxide, call your doctor immediately.
- tell your doctor if you are on a low-salt, low-sugar, or other special diet.
If you are taking magnesium oxide on a regular schedule, take the missed dose as soon you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Magnesium oxide may cause side effects. To avoid unpleasant taste, take the tablet with citrus fruit juice or carbonated citrus drink. Tell your doctor if either of these symptoms are severe or do not go away:
- cramping
- diarrhea
If you experience any of the following symptoms, call your doctor immediately:
- rash or hives
- itching
- dizziness or lightheadedness
- mood or mental changes
- unusual tiredness
- weakness
- nausea
- vomiting
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online (http://www. fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA’s Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can’t be awakened, immediately call emergency services at 911.
- Mag-Ox®
- Maox®
- Uro-Mag®
Last Revised – 10/15/2015
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Magnesium Oxide Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing
Uses
This medication is a mineral supplement used to prevent and treat low amounts of magnesium in the blood. Some brands are also used to treat symptoms of too much stomach acid such as stomach upset, heartburn, and acid indigestion. Magnesium is very important for the normal functioning of cells, nerves, muscles, bones, and the heart. Usually, a well-balanced diet provides normal blood levels of magnesium. However, certain situations cause your body to lose magnesium faster than you can replace it from your diet. These situations include treatment with “water pills” (diuretics such as furosemide, hydrochlorothiazide), a poor diet, alcoholism, or other medical conditions (such as severe diarrhea/vomiting, stomach/intestinal absorption problems, poorly controlled diabetes).
How to use Magnesium Oxide
Take this product by mouth as directed. Follow all directions on the product package. If you have any questions, ask your doctor or pharmacist.
It is best to take magnesium supplements with a meal to reduce stomach upset and diarrhea unless otherwise directed by the product instructions or your doctor.
Take each dose with a full glass (8 ounces or 240 milliliters) of water unless your doctor directs you otherwise. Swallow extended-release capsules and delayed-release/enteric coated tablets or capsules whole. Do not crush or chew extended-release or delayed-release/enteric coated capsules or tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.
If you are taking the chewable tablets, chew each tablet thoroughly before swallowing.
If you are using a liquid product, use a medication measuring device to carefully measure the dose. Do not use a household spoon because you may not get the correct dose. If you are using a suspension, shake the bottle well before each dose.
Take this medication regularly in order to get the most benefit from it. Remember to take it at the same time(s) each day. Dosage is based on your medical condition and response to treatment. Do not increase your dose or take it more often than directed on the product package or by your doctor. Too much magnesium in the blood can cause serious side effects.
Tell your doctor if symptoms of low magnesium blood levels (such as muscle cramps, tiredness, irritability, depression) last or get worse. If you think you may have a serious medical problem, get medical help right away.
Side Effects
Stomach upset and diarrhea may occur. Taking this product with a meal helps to reduce these effects. If either of these effects last or get worse, tell your doctor or pharmacist promptly.
If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US –
In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Precautions
Before taking a magnesium supplement, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
If you have the following health problem, consult your doctor or pharmacist before using this product: kidney disease.
Liquids, powders, or some other forms of this product may contain sugar and/or aspartame. Liquid products may also contain alcohol. Caution is advised if you have diabetes, alcohol dependence, liver disease, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet. Ask your doctor or pharmacist about using this product safely.
During pregnancy, this product should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is not known whether this product passes into breast milk. Consult your doctor before breast-feeding.
Interactions
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.
Some products that may interact with this drug are: cellulose sodium phosphate, digoxin, sodium polystyrene sulfonate.
Magnesium can bind with certain medications, preventing their full absorption. If you are taking a tetracycline-type medication (such as demeclocycline, doxycycline, minocycline, tetracycline), separate the time of the dose from the time of the magnesium supplement dose by at least 2 to 3 hours. If you are taking a bisphosphonate (for example, alendronate), a thyroid medication (for example, levothyroxine), or a quinolone-type antibiotic (such as ciprofloxacin, levofloxacin), ask your doctor or pharmacist about how long you should wait between doses and for help finding a dosing schedule that will work with all your medications.
Check the labels on all your prescription and nonprescription/herbal products (such as antacids, laxatives, vitamins) because they may contain magnesium. Ask your pharmacist about using those products safely.
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Overdose
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include slow heartbeat, severe drowsiness, dizziness, confusion, muscle weakness, loss of consciousness.
Lab and/or medical tests (such as magnesium blood levels, kidney function) should be done while you are taking this medication. Keep all medical and lab appointments. Consult your doctor for more details.
Magnesium supplements are available in different forms with different amounts of magnesium. Many are available without a prescription. Ask your doctor or pharmacist for help in selecting the best product for you.
Eat a well-balanced diet. Foods high in magnesium include avocados, bananas, beans, whole grain cereals, green vegetables, and nuts.
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Images
magnesium oxide 400 mg (241.3 mg magnesium) tablet
Color: whiteShape: roundImprint: R 339
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium 250 mg (as magnesium oxide) tablet
Color: whiteShape: roundImprint:
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium oxide 400 mg (241.3 mg magnesium) tablet
Color: whiteShape: roundImprint: GP400
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium oxide 400 mg (241. 3 mg magnesium) tablet
Color: whiteShape: roundImprint: MgO
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium oxide 400 mg (241.3 mg magnesium) tablet
Color: whiteShape: roundImprint:
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium 240 mg (as magnesium oxide) oral powder packet
Color: whiteShape: Imprint:
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium oxide 400 mg (241.3 mg magnesium) tablet
Color: whiteShape: roundImprint: T
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium oxide 400 mg (241.3 mg magnesium) tablet
Color: whiteShape: roundImprint:
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium oxide 400 mg (241.3 mg magnesium) tablet
Color: whiteShape: roundImprint: logo and 174
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium oxide 500 mg capsule
Color: clearShape: oblongImprint:
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium oxide 400 mg (241.3 mg magnesium) tablet
Color: whiteShape: roundImprint:
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium 250 mg (as magnesium oxide) tablet
Color: whiteShape: ovalImprint:
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium 250 mg (as magnesium oxide) tablet
Color: whiteShape: roundImprint:
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium oxide 420 mg tablet
Color: whiteShape: roundImprint:
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium oxide 500 mg tablet
Color: whiteShape: oblongImprint:
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium 400 mg (as magnesium oxide) tablet
Color: whiteShape: oblongImprint:
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium oxide 400 mg (241.3 mg magnesium) tablet
Color: whiteShape: roundImprint: logo and 174
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium 400 mg (as magnesium oxide) capsule
Color: dark brownShape: oblongImprint:
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium 250 mg (as magnesium oxide) tablet
Color: tanShape: roundImprint:
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium oxide 400 mg (241.3 mg magnesium) tablet
Color: whiteShape: roundImprint: T
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium 250 mg (as magnesium oxide) tablet
Color: whiteShape: roundImprint:
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium 250 mg (as magnesium oxide) tablet
Color: whiteShape: oblongImprint:
This medicine is a white, round, scored, tablet imprinted with “R 339”.
magnesium oxide 400 mg (241.3 mg magnesium) tablet
Color: whiteShape: roundImprint: logo and 174
This medicine is a white, round, scored, tablet imprinted with “R 339”.
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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
Magnesium oxide is in demand in industry, food industry and medicine
Magnesium oxide is an inorganic compound with the formula MgO. In the literature, you can also find such names as magnesium oxide, magnesia, burnt magnesia.
The substance occurs naturally as a fairly rare periclase mineral. In industrial production, MgO is obtained by:
• processing of natural raw materials: dolomite and magnesite;
• decomposition of magnesium sulfate MgSO4 at high temperatures;
• decomposition of white magnesia 3MgCO3×Mg (OH)2×3h3O or magnesium carbonate MgCO3.
Properties
Externally, magnesium oxide is a soft, light, friable, finely crystalline powder substance of white or light gray color, odorless, with a slightly earthy taste. It absorbs water very well, but almost does not dissolve in water itself. Does not dissolve in alcohols; absorbs fats and liquids. Does not cake, does not crumple, pours well, but does not form dust. When heated above +2000 ° C, it becomes volatile. It melts at temperatures around +3000 °C. Able to burn, non-explosive, non-toxic.
Fine loose powder absorbs moisture and carbon dioxide from the air well. It actively reacts with acids to form magnesium salts. In reaction with water, it forms magnesium hydroxide Mg(OH)2. It is destroyed in chemical reactions with bromine trifluoride BrF3, phosphorus pentachloride PCl5. If magnesia is calcined, then it ceases to absorb water and interact with acids.
2000 ml reagent bottle, 9 divisions0019 | Magnesium carbonate | Dust-proof respirator LEPESTOK L-200 up to 4PDK |
Precautions
The reagent is low toxic, but may cause irritation on direct contact with the eyes, respiratory organs; swallowing can lead to intestinal upset. Allergic reactions are possible in case of individual intolerance.
Magnesium oxide workstation must be located in a room with forced ventilation. Employees must wear masks or respirators, respiratory and eye protection goggles, and rubber gloves. Smoking is prohibited in the workplace.
The reagent is packaged and transported in hermetically sealed plastic or multilayer paper bags. The integrity of the packaging should be strictly monitored, as the product actively absorbs moisture from the environment.
Store magnesia in a dry, well-ventilated warehouse out of direct sunlight. The substance should be placed away from heating devices, acids, halogens. In laboratories, it is stored in sealed glass or plastic containers with ground or screw caps.
Application
The industry produces several types of burnt magnesia, which differ in their consumer properties: weight, chemical activity, sorption ability, etc.
• High weight grades of magnesia are used to make refractory materials.
• Medium-heavy grades are in demand in the construction industry for various fire-resistant building materials (xylitol, concrete) and magnesia cements.
• Lightweight grades used as sorbents for refining petroleum derivatives; as a filler in the rubber industry, a filler in heating elements.
• Light burnt magnesia is used in medicine to reduce the acidity of gastric juice, to stimulate the muscles of the intestines as a laxative, to prevent the formation of kidney stones, in case of acid poisoning, as an anti-inflammatory agent in diseases of the gastrointestinal tract.
• In the pharmaceutical industry, it is part of mineral and vitamin complexes with magnesium.
• Light magnesia in the food industry is a food additive E530 (emulsifier, stabilizer) approved in the EU and the Russian Federation. It is used for the production of milk powder and cream, oils and margarines, chocolate and cocoa products.
• In the cosmetic industry – a stabilizer, absorbent, buffering agent in the manufacture of powders, blush, talc and other bulk products. Used in decorative cosmetics, sunscreens, face and hair masks, blackheads, shampoos, deodorants, baby powders, etc.
• Finely dispersed light magnesia is used in radio electronics enterprises as a fine abrasive.
• In sports, anti-slip powder for the hands of athletes and climbers.
• Used as a white color standard, it has absolute reflectivity over a wide range of the spectrum.
• The reagent is part of the protective layer of LCD screens; used in the manufacture of paper; in demand at waste processing enterprises to control the solubility of radionuclides.
• In agriculture, anti-caking additive in fertilizers; independent magnesium-containing fertilizer and feed additive for animals with a lack of magnesium in pastures.
BP drug interaction Included in preparations: Pharmacological actionAntacid. Magnesium oxide, turning into magnesium hydroxide when interacting with water, neutralizes free hydrochloric (hydrochloric) acid in the stomach, reduces the peptic activity of gastric juice. When taken on an empty stomach, the antacid effect is short-lived (about 30 minutes), when taken after meals, its duration increases to 3-4 hours. Magnesium chloride, formed in the stomach, has a laxative effect in the intestines. By increasing the osmotic pressure in the intestinal lumen, it increases peristalsis. There is evidence that magnesium oxide in combination with pyridoxine reduces the formation of calcium oxalate and prevents the development of oxalate nephrourolithiasis. Indications of the active substance |
K21.0 | Gastroesophageal reflux with esophagitis |
K25 | Gastric ulcer |
K26 | Duodenal ulcer |
K27 | Peptic ulcer |
K29 | Gastritis and duodenitis |
K30 | Functional dyspepsia (digestive disorder) |
K59.0 | Constipation |
K86.1 | Other chronic pancreatitis |
N20 | Kidney and ureter stones |
N21 | Lower urinary tract stones |
R10. 1 | Pain localized in the upper abdomen |
R12 | Heartburn |
T54.2 | Corrosive acids and acid-like substances |
Dosing regimen
For oral administration, a single dose is 0.25-2.5 g. The frequency and duration of use depend on the indications.
Side effects
Possible: diarrhea, allergic reactions.
Contraindications for use
Hypersensitivity to magnesium oxide; hypermagnesemia, children’s age (depending on the dosage form).
Use in disorders of kidney function
Use with caution in renal impairment.
In patients with impaired renal function, the use of magnesium oxide may develop hypermagnesemia.
Use in children
May be used in children according to indications, in doses and dosage forms recommended according to age. It is necessary to strictly follow the instructions in the instructions for magnesium oxide preparations on contraindications for use in children of different ages of specific dosage forms of magnesium oxide.
Special instructions
Use with caution in renal failure.
In patients with impaired renal function, the use of magnesium oxide may develop hypermagnesemia.
Usually used in combination with aluminum containing antacids to reduce gastrointestinal side effects and increase duration of action.
Magnesium oxide can be used in cases of magnesium deficiency in the body, and also as a dietary supplement.
Drug interactions
When used simultaneously with antacids containing aluminum, side effects from the gastrointestinal tract are reduced and the duration of action of antacids is increased.
When used simultaneously with indomethacin, it is possible to reduce the concentration of indomethacin in the blood plasma, reduce the irritating effect of indomethacin on the gastrointestinal tract.