What is thymus extract. How does thymus extract work. What are the potential benefits of thymus extract. Are there any side effects or risks associated with thymus extract. Who should avoid using thymus extract.

Understanding Thymus Extract: Origin and Function

Thymus extract is derived from the thymus glands of cows and has garnered attention for its potential health benefits. The thymus gland plays a crucial role in the human immune system, particularly in the production of T-cells. These cells are essential components of our body’s defense mechanism against various pathogens and diseases.

But how exactly does thymus extract work? The extract is believed to contain bioactive compounds that may enhance or modulate immune function. By introducing these compounds into the human body, thymus extract might potentially boost overall immunity and help combat certain health conditions.

The Composition of Thymus Extract

Thymus extract typically contains a complex mixture of proteins, peptides, and other bioactive molecules. These components are thought to interact with the human immune system, potentially influencing its function and effectiveness. However, it’s important to note that the exact composition and potency of thymus extract products can vary significantly depending on the source and manufacturing process.

Potential Health Benefits of Thymus Extract

While research on thymus extract is ongoing, several potential health benefits have been identified. It’s crucial to understand that while some uses show promise, many require further scientific investigation to confirm their effectiveness.

Dilated Cardiomyopathy

Can thymus extract help with weakened and enlarged heart conditions? Early research suggests that taking calf thymus extract along with standard therapy may improve heart function, alleviate certain symptoms, and enhance exercise capacity in some individuals with dilated cardiomyopathy. This potential benefit is particularly intriguing and warrants further investigation.

Food Allergies

For children struggling with food allergies, thymus extract might offer some relief. When combined with an elimination diet, calf thymus extract has shown potential in reducing the number of allergic reactions. This could be a promising avenue for managing food sensitivities in young patients.

Respiratory Infections

Does thymus extract have any effect on respiratory health? Some studies indicate that oral administration of calf thymus extract may decrease the frequency of infections or coughing episodes in both adults and children prone to airway infections. This potential benefit could be particularly valuable for individuals with recurrent respiratory issues.

Exploring Other Potential Applications of Thymus Extract

While the aforementioned uses have shown some promise, thymus extract is being studied for a variety of other conditions. However, it’s important to note that current evidence is insufficient to draw definitive conclusions about its effectiveness in these areas.

• Hay fever
• Asthma
• Common cold and flu
• Herpes infections (cold sores and shingles)
• Hepatitis B and C
• Chronic fatigue syndrome
• Autoimmune conditions
• Cancer

These potential applications highlight the wide-ranging interest in thymus extract as a therapeutic agent. However, more rigorous scientific studies are needed to establish its efficacy in these areas.

Safety Considerations and Potential Side Effects

Is thymus extract safe for consumption? When taken orally, thymus extract is generally considered possibly safe for most people when used appropriately. However, as with any supplement, there are potential risks and considerations to keep in mind.

Contamination Concerns

One of the primary concerns with thymus extract is the potential for contamination, given its animal origin. While there have been no reported cases of disease transmission from thymus extract use, the theoretical risk of contamination with diseased animal parts exists. This includes the remote possibility of exposure to prion diseases like “mad cow disease” (bovine spongiform encephalopathy, BSE).

Administration Route Considerations

While oral administration of thymus extract has a established safety profile, the same cannot be said for injectable forms. There is insufficient reliable information about the safety and potential side effects of thymus extract when given as a shot. Therefore, caution is advised when considering this route of administration.

Who Should Exercise Caution with Thymus Extract?

Certain groups of individuals should be particularly cautious when considering the use of thymus extract. These include:

1. Pregnant and breastfeeding women: Due to lack of reliable safety data, it’s advisable to avoid thymus extract during pregnancy and while breastfeeding.
2. Individuals with weakened immune systems: People with compromised immunity, such as HIV/AIDS patients or organ transplant recipients, may be at higher risk of infection from animal-derived products. They should only use thymus extract products certified as germ-free.
3. Those taking immunosuppressive medications: Thymus extract may interact with drugs that suppress the immune system, potentially increasing the risk of infections.

It’s crucial for these individuals to consult with a healthcare professional before considering thymus extract supplementation.

Potential Interactions with Medications

Are there any known drug interactions with thymus extract? One notable interaction is with medications that suppress the immune system. Thymus extract, due to its potential immune-boosting properties, may counteract the effects of these drugs or increase the risk of infections.

Some medications that may interact with thymus extract include:

• Azathioprine (Imuran)
• Basiliximab
• Other immunosuppressive drugs used in organ transplantation or autoimmune disease management

Individuals taking these medications should avoid thymus extract unless explicitly advised otherwise by their healthcare provider.

Dosage and Administration of Thymus Extract

How should thymus extract be taken, and what is the appropriate dosage? The optimal dosage of thymus extract can vary depending on several factors, including the specific health condition being addressed, the individual’s age and overall health status, and the particular product being used.

Given the variability in thymus extract products and the lack of standardized dosing guidelines, it’s crucial to follow the manufacturer’s instructions or consult with a healthcare professional for personalized advice. Some general considerations include:

• Start with a lower dose and gradually increase if needed
• Be consistent with the timing of administration
• Monitor for any adverse effects or changes in symptoms
• Discontinue use if any concerning side effects occur

Remember, more is not always better when it comes to supplements. Adhering to recommended dosages is essential for maximizing potential benefits while minimizing risks.

Duration of Use

The appropriate duration of thymus extract supplementation can also vary depending on the intended use and individual response. Short-term use (a few weeks to a few months) is more common and generally considered safer. Long-term use should be approached with caution and under the guidance of a healthcare provider.

Quality Considerations: Choosing a Thymus Extract Product

How can one ensure they’re selecting a high-quality thymus extract product? Given the variability in thymus extract products, choosing a reputable source is crucial. Here are some factors to consider:

1. Source of the extract: Look for products that clearly state the origin of the thymus glands used.
2. Manufacturing standards: Choose products from companies that adhere to Good Manufacturing Practices (GMP).
3. Third-party testing: Products that have undergone independent quality testing may offer additional assurance.
4. Standardization: Look for products that specify the concentration of active compounds.
5. Purity: Ensure the product is free from unnecessary additives or contaminants.

Remember, the FDA does not strictly regulate dietary supplements, including thymus extract. Therefore, it’s up to the consumer to be diligent in selecting a high-quality product.

Potential Red Flags

Be wary of products that make exaggerated claims or promise miraculous results. Reputable manufacturers will typically provide balanced information about their products, including potential benefits and limitations.

The Future of Thymus Extract Research

What does the future hold for thymus extract research? While current studies have shown promise in certain areas, there’s still much to learn about the potential applications and long-term effects of thymus extract supplementation.

Future research directions may include:

• Large-scale clinical trials to confirm effectiveness for various conditions
• Studies on optimal dosing and administration methods
• Investigation of potential synergistic effects with other treatments
• Long-term safety studies
• Exploration of thymus extract’s mechanisms of action at the cellular level

As our understanding of the immune system continues to evolve, so too may our appreciation for the potential role of thymus extract in supporting health and managing various conditions.

Challenges in Thymus Extract Research

One of the main challenges in thymus extract research is the variability in product composition and quality. Standardization of extracts and rigorous quality control measures will be crucial for conducting meaningful clinical studies and drawing reliable conclusions.

Integrating Thymus Extract into a Holistic Health Approach

How can thymus extract potentially fit into a broader health and wellness strategy? While thymus extract shows promise for certain conditions, it’s important to view it as a potential complement to, rather than a replacement for, established health practices.

A holistic approach to health that incorporates thymus extract might include:

1. A balanced, nutrient-rich diet
2. Regular physical activity
3. Stress management techniques
4. Adequate sleep and rest
5. Other evidence-based supplements as needed
6. Regular health check-ups and screenings

Remember, thymus extract should not be viewed as a miracle cure or a substitute for a healthy lifestyle. Instead, it may serve as one tool among many in supporting overall health and well-being.

Consulting with Healthcare Professionals

Before incorporating thymus extract or any new supplement into your health regimen, it’s crucial to consult with a qualified healthcare professional. They can provide personalized advice based on your individual health status, medical history, and current medications.

A healthcare provider can also help monitor your response to thymus extract and adjust the approach as needed. This collaborative approach ensures that you’re using thymus extract safely and effectively as part of a comprehensive health strategy.

Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

Overview

The human thymus gland is responsible for the production of some important immune cells, such as T-cells. Thymus extract is produced from the thymus glands of cows. Some people use it as medicine. But the quality and potency of thymus extract products can vary greatly.

Thymus extract is used for hay fever, infection of the airways, the common cold, flu, food allergies, asthma, weakened and enlarged heart (dilated cardiomyopathy), and many other conditions, but there is no good scientific evidence to support most of these uses.

Thymus extract may work by improving or boosting the immune system.

Uses & Effectiveness ?

Possibly Effective for

• Weakened and enlarged heart (dilated cardiomyopathy). Early research suggests that taking calf thymus extract along with usual therapy improves heart function, some symptoms, and the ability to exercise in some people with dilated cardiomyopathy.
• Food allergies. Taking calf thymus extract while following an elimination diet might reduce the number of allergic reactions in some children with food allergies.
• Infection of the airways. Some research shows that taking calf thymus extract by mouth may reduce the number of infections or coughing attacks in adults and children who get a lot of airway infections.

Insufficient Evidence for

• Hay fever. Early research shows that taking calf thymus extract for 4 months might reduce the number of allergic episodes in people with hay fever.
• Asthma. Early research shows that taking calf thymus extract may reduce the number of asthma attacks in children with asthma.
• Common cold.
• Flu (influenza).
• Cold sores (herpes labialis).
• Shingles (herpes zoster).
• Hepatitis B.
• Hepatitis C.
• Swelling (inflammation) of the nasal cavity and sinuses (rhinosinusitis).
• Chronic fatigue syndrome (CFS).
• Epstein-Barr virus (EBV).
• Mononucleosis.
• HIV/AIDS.
• Arthritis.
• Cancer.
• Rheumatoid arthritis (RA).
• An autoimmune disease that causes widespread swelling (systemic lupus erythematosus or SLE).
• Other conditions.

More evidence is needed to rate the effectiveness of thymus extract for these uses.

Side Effects

When taken by mouth: Thymus extract is POSSIBLY SAFE for most people when taken appropriately.

Because thymus extract comes from animals, there is concern about contamination with diseased animal parts. However, so far, there are no reports of diseases in humans due to use of contaminated thymus extract. There is also some concern about the possibility of catching “mad cow disease” (bovine spongiform encephalitis, BSE) from products that come from animals. There are no reports of getting “mad cow disease” from thymus extract. But it is probably wise to avoid animal products from countries where “mad cow disease” has been found.

When given as a shot: There isn’t enough reliable information to know if thymus extract is safe or what the side effects might be.

Special Precautions and Warnings

When taken by mouth: Thymus extract is POSSIBLY SAFE for most people when taken appropriately.

Because thymus extract comes from animals, there is concern about contamination with diseased animal parts. However, so far, there are no reports of diseases in humans due to use of contaminated thymus extract. There is also some concern about the possibility of catching “mad cow disease” (bovine spongiform encephalitis, BSE) from products that come from animals. There are no reports of getting “mad cow disease” from thymus extract. But it is probably wise to avoid animal products from countries where “mad cow disease” has been found.

When given as a shot: There isn’t enough reliable information to know if thymus extract is safe or what the side effects might be. Pregnancy and breast-feeding: There isn’t enough reliable information to know if thymus extract is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Weakened immune system: People who have a weakened immune system (HIV/AIDS patients, for example) or people who are taking drugs to weaken their immune system (organ transplant recipients, for example) have a higher risk of infection. These people should avoid thymus extract products unless these products are certified germ-free.

Interactions ?

Moderate Interaction

Be cautious with this combination

• Medications that decrease the immune system can increase your chances of getting sick. Thymus extract is made from animals. There is some concern that products made from animals might contain harmful diseases and cause infections. Taking medications that decrease the immune system along with thymus extract might increase your chances of getting sick. Do not take thymus extract if you are taking medications that decrease the immune system.

  Some medications that decrease the immune system include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and others.

Dosing

The following doses have been studied in scientific research:

ADULTS

BY MOUTH:

• For infection of the airways: Thymomodulin (calf thymus extract) 120 mg daily, on 20 days of each month, for 4 months.

BY INJECTION:

• For weakened and enlarged heart (dilated cardiomyopathy): Thymomodulin (calf thymus extract) 10 mg injected under the skin three times each week for 3 months.

CHILDREN

BY MOUTH:

• For food allergies: Thymomodulin (calf thymus extract) 120 mg daily for 3 months.
• For infection of the airways: Thymomodulin (calf thymus extract) 120 mg daily, on 20 days of each month, for 4 months. Thymomodulin 3 mg/kg daily for 3 months.

View References

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.

9 Things to Know About Thymus Extract

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Thymus extract is sometimes touted as an herb that may boost your immune system and fight off symptoms of allergies, asthma, and autoimmune disorders. Is there any truth to these claims?

Read on to learn what thymus extract is and which claims are backed by research.

Your thymus gland sits below your thyroid gland and above your heart. It’s pinkish-gray in color and shaped like two ovals.

The thymus is a unique organ in that it works before birth and throughout puberty. When you hit puberty, the gland starts to shrink and fatty tissue replaces it.

By the time you reach age 75, your thymus gland is usually nothing more than fatty tissue. As you age, your thymus gland gets smaller and can become less effective.

Although the thymus gland stops working pretty early on in life, it still fulfills several key purposes. The thymus is responsible for producing and releasing the hormone thymosin. This hormone is responsible for stimulating the production of T lymphocytes, or T cells for short.

These immune system cells help ward off infection in the body. Once produced in the thymus, T cells travel to your lymph nodes, where they fight infection.

Scientists also study T cells for their potential cancer-fighting abilities.

Thymus extract is made from the thymus glands of cows, typically calves. It can also be synthetically produced.

Note that there is a difference between thymus extract and extract from Thymus serpyllum. The latter comes from the thyme plant, and not cows.

Since the thymus gland is an important part of the immune system in both animals and people, some people think thymus extract has medicinal benefits. They believe that consuming it can boost your immune system, helping you fight off various diseases.

The idea of using animal glands or organs for medicinal purposes is hundreds of years old. Also known as glandular therapy, this concept is based on the belief that “like heals like.”

For example, glandular therapists believe that consuming nutrients from an animal’s healthy liver can help repair your liver if it’s damaged.

In the 1900s, scientists began to look for active chemicals in organ foods that have health benefits. Scientists and manufacturers have since isolated many chemicals, such as thyroid extracts, estrogen, and cortisol. Thymus extract is one of the chemicals they’ve extracted.

Thymus extract is now sold as a dietary supplement. It’s also sold in a more purified form, called thymomodulin. Both varieties are available in capsule, pill, or liquid form at many health stores and online.

Some evidence suggests that thymus extract might help ward off respiratory infections, such as bronchitis. This research has focused on people prone to respiratory infections.

Other reasons a person may take thymus extract include fighting off hay fever (allergic rhinitis) and sinusitis, which can all affect the respiratory system.

Thymus extract is also sometimes taken to help treat eczema (atopic dermatitis), an inflammatory skin condition that can develop alongside hay fever and allergic asthma.

Some asthma attacks are triggered by an overactive immune system. Some research suggests that taking thymomodulin helps reduce the severity of asthma attack symptoms. It may also help reduce the frequency of asthma attacks.

Some people have used thymus extract to treat conditions such as hepatitis B, hepatitis C, and HIV. It’s thought that the supplements may boost your immune system and help your body fight against these viral infections.

However, you should exercise extreme caution when taking any supplement for an active viral infection, especially if your immune system is compromised due to HIV. Some animal-derived supplements may be contaminated.

Thymus extract is sometimes marketed as an alternative treatment for autoimmune diseases, such as rheumatoid arthritis, lupus, type 1 diabetes, multiple sclerosis (MS), Graves’ disease, and Celiac disease.

Autoimmune diseases develop when your body mistakenly attacks healthy cells and tissues by treating them as invaders. Older research from 1976 has explored the possibility that thymus extract may help reverse thymosin imbalances that may contribute to such diseases.

However, it’s not clear whether thymus extract can help reverse the effects or prevent the progression of any autoimmune disease.

Allergic reactions happen when your immune system treats an otherwise harmless substance as a threat. As a result, it goes into attack mode.

Some people believe that thymus extract may help calm rather than boost your immune system if you have food allergies. Thymomodulin may help prevent allergic reactions, as reported in a 2015 study.

Thymus extract is sometimes added to cosmetics and hair care products as an anti-aging ingredient. The extract contains amino acids and peptides, which are thought to help keep the skin supple and smooth.

Ingredients lists on skin care products may call bovine thymus “bovine collagen.” The extract is added to moisturizers, facial masks, and more.

No side effects from thymus extract have been reported. But it’s important to note that dietary supplements aren’t well regulated by the Food and Drug Administration (FDA).

For example, they aren’t covered by regulations that ban the sale of food products from cows with mad cow disease.

Also, the FDA doesn’t currently list registered skin care products that have thymus extract added to them, yet many exist on the market. For this reason, you should always use caution when buying thymus extract.

Some studies have used an injectable form of thymus extract. However, many of these studies conducted in the mid- to late-1990s used small sample sizes.

Other studies have focused on oral supplements. Overall, more research is needed to support the proposed uses of thymus extract in fighting diseases.

Talk to your doctor before trying thymus extract or any other dietary supplements. They can help you assess the potential benefits and risks.

More research is needed to explore the potential benefits and risks of taking thymus extract. Some studies suggest it may help prevent or treat certain conditions, such as respiratory infections and asthma.

Always check with your doctor before trying a new dietary supplement or alternative treatment. It’s possible that bovine extract could react adversely with a medication you may be taking.

Don’t stop taking other medications in favor of thymus extract unless directed by a doctor.

Did you know?

While there’s not yet enough research to determine recommended doses, a typical daily dose is 750 milligrams (mg) of pure thymus or 120 mg of thymomodulin.

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Immunoregulatory peptides

Specialists
oncologists

Large group – immunoregulatory peptides – includes subgroups: thymic peptides, bone marrow, splenic and others. These are drugs, the prototypes of which are natural bioregulators produced by organs or individual tissues that transmit information and control many biochemical reactions. Such substances have a peptide-protein nature and are called cytomedins; they are able to regulate the cell population from which they are isolated. And they are isolated from the tissue of the brain, thymus, bone marrow, spleen, lymph nodes.

Thymic immunoregulatory peptides are represented by Taktivin , Thymosin , Thymalin , Timaktide , Thiostimulin [23]. All drugs contain thymosin-alpha and are largely close to each other in action.

The thymus is a unique organ of the neuroendocrine and immune systems capable of producing hormones: thymopoietin (blocks neuromuscular transmission, affects the precursors of T-lymphocytes), thymic humoral factor (activates T-cells), thymic factor X (restores the number of T-lymphocytes ), thymulin (affects the stages of differentiation of T-lymphocytes and T-killers), thymosin-alpha 1 (affects the early stages of T-cells and T-helpers), thymosin-alpha 3 (ACTH-like action), thymosin-alpha 7 (affects the differentiation of T-suppressors and the late stages of T-lymphocytes), thymosin-beta 4 (early stages of T-lymphocyte differentiation), etc. [116]. Under the action of these hormones, the maturation of thymus-dependent lymphocytes in the thymus and outside it, which are responsible for cell-type immune responses, occurs. Indirectly, hormones affect the activity and maturation of macrophages and natural killers, stimulate antibody formation.

Thymus preparations have been known since the 1970s and have been widely used by foreign oncologists for special treatment for 30 years [54]. Initially, extracts from animal organs were isolated to compensate for 50-70% of thymus deficiency in the elderly with the ultimate goal of rejuvenating the body.

Thymosin is the first thymus peptide. Isolated from calf thymus in the laboratory of the University of Texas School of Medicine at 1965 A.L. Goldstein’s 28 polypeptide components were named thymosin. In an animal experiment, it was proved that the drug is able to restore immunoreactivity. Later it was found that only a part of the molecule, called thymopentin, has activity.

Thymosin stimulates and modulates various functions of T-suppressors and natural killers, stimulates the formation of a number of lymphokines, promotes the maturation of lymphocytes [51]. There is evidence that thymosin is involved in the interaction of the immune and hypothalamic-pituitary-gonadal systems. Thymosin increases the secretion of gonadotropins, and when steroids act on the thymus, the production of its own thymosins decreases.

Thymogen-alpha1 analog zadaxin, identical to the human thymus peptide, has been synthesized to be used in the treatment of chronic hepatitis and as an adjuvant (immune response enhancement) for influenza vaccination. Thymosin-beta 4 was isolated from the heart of the embryo, which in mice not only helps to reduce the scar in myocardial infarction, but also reduces the size of the left ventricle during its dilation.

Taktivin is obtained from bovine thymus. In immunodeficiency states, the drug normalizes the quantitative and functional parameters of T-lymphocytes, regardless of whether they were reduced or increased before treatment. Stimulates the production of lymphokines, including alfa- and gamma-interferons, restores the activity of T-killers and stem hematopoietic cells.

Active in persistent disorders of T-cell immunity arising from infectious and purulent processes, lymphoproliferative diseases, tuberculosis. The drug is effective only in cases where the deficiency of T-lymphocytes is the main pathogenetic link of the disease.

In malignant tumors, Taktivin is prescribed 1 ml (100 mcg) of a 0.01% solution subcutaneously once a day for 5-6 days during breaks in specific therapy, then maintenance therapy 1 time in 7-10 days until the parameters of the T-immunity system normalize . To prevent postoperative infection, Taktivin is administered within 2 days before and 3 days after the intervention.

To prevent purulent-septic complications after radical mastectomy, 12 patients were injected with 400 μg of 0.01% taktivin on days 1, 2, 5 and 7 subcutaneously into the forearm tissue, then the cuff of the AKPU-5 pneumatic unit was applied to the hydration infiltrate. It was assumed that this creates a high concentration of Taktivin in the lymphatic fluid [75]. Initially, all patients had a decrease in cellular and humoral immunity. As a result of therapy, the number of T-lymphocytes, Ig A, M, G, plasma cells increased. The level of B-lymphocytes did not change.

Some authors recommend preparing the release of T-cell precursors from the bone marrow with methyluracil or sodium nucleinate for 7-10 days before prescribing Taktivin [50]. The drug is contraindicated in atopic bronchial asthma.

Timalin is obtained by extraction from the thymus gland of cattle, consists of 38 amino acids. Immunomodulator and biostimulator. Regulates the number and ratio of T- and B-lymphocytes and their populations, stimulates cellular immunity reactions, enhances phagocytosis. Timalin affects cyclic nucleotides and calcium metabolism and thus activates cell proliferation and differentiation. Improves the processes of cellular metabolism, thereby accelerating tissue regeneration.

Effective in bone fractures, radiation necrosis of tissues, trophic ulcers, purulent processes of the skin and soft tissues. It is administered intramuscularly at 5-20 mg daily up to 5 times.

Timaktid is a complex of polypeptides from the thymus glands of seals, calves, and lambs [52]. Induces proliferation and differentiation of T-cells, activates the phagocytic function of neutrophils, stimulates megakaryocytic germ.

It is used for chronic non-specific lung diseases, for the prevention of postoperative complications, reduces the incidence of complications in radiation and chemotherapy. There is a reduction in hospital stay by half in the treatment of purulent-inflammatory processes of the maxillofacial region with timaktid.

Available as buccal tablets, well absorbed in the mouth. The drug is taken 1.5-2 hours before dinner, dissolving the tablet under the tongue or behind the cheek. The interval between doses is 4 days. The course is 5-7 tablets, the course can be repeated in 1-2 months [24].

Thymomulin – extract isolated from calf thymus, consists of two fractions. It belongs to pleiotropic hormones due to the influence on two systems: immune and nervous.

Able to increase the number and activity of T-lymphocytes, suppresses the induction of early and induces late differentiation of B-lymphocytes.

Intramuscular injection of 1 mg/kg of body weight per day for the first week, then 2-3 times a week. Duration depends on individual effectiveness. It is rarely used in Russia, probably due to the availability of low-cost domestic drugs.

Bone marrow immunoregulatory peptides are peptides produced by bone marrow cells represented by Myelopid . Myelopeptides (MPs) are not species-specific, that is, derived from an animal, they work successfully in humans or other animal species.

The first of the discovered biological activities of myelopeptides was their ability to stimulate the production of antibodies at the peak of the immune response, and the response was enhanced with a lack of antibody-producing cells by “turning on” reserve cells [30].

Changes in the immune system under the influence of immunomodulators occur in two directions. If activation follows a natural path, then this path is called centripetal – from the center to the periphery; if various components of the immune system are activated (IL, IFN, TNF, etc.), and through them immunocompetent cells, then this path is called centrifugal – from the periphery to the center [25]. Myelopid activates the system in two directions.

Myelopid is a mixture of unidentified peptides from porcine bone marrow cell culture [26]. To date, 4 myelopeptides that are part of Myelopide have been isolated and studied. Each of them reproduces one of the activities of the drug, strictly defined, having its own target cell and acting on a specific link in the immune system.

MP-1 acts on the T-helper, connecting with it, and normalizes the ratio of helpers and suppressors.

MP-2 normalizes the phenotype and functional activity of T-lymphocytes suppressed by tumor toxins. In an experiment on the combined treatment of malignant tumors in mice, MP-2 made it possible not only to potentiate the effect, but also to significantly (8 times) reduce the cytotoxic dose of cisplatin. The effectiveness of MP-2 is inversely proportional to the degree of immune suppression: the lower the immunity, the higher the effectiveness of MP-2.

MP-3 stimulates the activity of macrophages, enhancing their cytotoxicity, antigen expression and the ability to present antigenic peptides to lymphocytes. [27].

MP-4 induces terminal differentiation of leukemic cells [28,29,30,31].

When compared with traditional methods of postoperative management of oncological patients, the use of myelopide significantly reduces the number of purulent-septic complications, contributes to the prevention of suture failure of interintestinal anastomoses, and reduces postoperative mortality. The clinic noted that after a course of immunocorrective therapy in patients with postoperative complications, only partial normalization of the parameters of individual immunity links is observed, which is delayed compared to the clinical effect. Therefore, rehabilitation should be long enough [53]. The standard course of myelopide is 3-6 mg subcutaneously daily or every other day 3-5 times.

Of the peptides of various origins , alfetin , affinoleukin and anaferon have been used in the clinic.

Alfetin consists of highly purified alpha-fetoprotein and rheopolyglucin. It is obtained from abortive blood by fractionation. The drug modulates the action of certain cytokines and regulatory factors, in particular, enhances the action of alpha-interferon and tumor necrosis factor, modulates the activity of prostaglandins.

Alfetin is used in the complex therapy of autoimmune diseases caused by a violation of the synthesis of cytokines that regulate T-cell immunity: ulcerative colitis, Hashimoto’s disease, and other immunopathological conditions.

Daily intramuscular or intravenous injection of 1-4 mg/kg body weight 1-2 times a day. The course of treatment is 14-30 days. You can repeat the treatment after 2-3 months. The drug potentiates the action of steroid hormones and non-narcotic analgesics [32].

Anaferon contains antibodies to interferon gamma and is used for the prevention and treatment of acute respiratory viral infections.

Affinoleukin is used for ophthalmic herpes. Both drugs do not affect antitumor immunity.

Meshcheryakova N.G.

Thymus extract. We activate the human immune system.

Thymus extract.
The human immune system loses its strength and ability to resist viruses and bacteria with age. To solve the problem of activating the human immune system, an extract of the Thymus is called, which is able to set the body to work properly.

The medical community is trying, on the contrary, to preserve the system of treatment that is accepted today. So I was talking with my friend, he is the head of the Bayer company for the production of new drugs. Businessman, WPO member, just like me. He spoke about two health care systems that existed in the Soviet Union and exist today in the world in everything. And in Russia, it has now also become stereotypical. In the Soviet Union, doctors were paid money from the budget and they did not have to earn money, so any new medicines, any developments were welcome, they were accepted. Our doctors were very much ahead of the whole world in many medical disciplines.
In America, the situation is completely different, you need to earn money. How will you earn, of course, the longer you treat the patient, the more money he brings you. Therefore, it must be said that Alzheimer’s is incurable, diabetes is incurable. The more variations of all kinds of drugs you release the better, the more you sell. Therefore, it is necessary to treat not specific diseases, but specific manifestations, that is, symptoms. All medicine in the world today is symptomatic, it treats the symptoms.
Well, to tell you something so that people can understand, if you put it in, of course. Let’s say something happened to your kidney. She stopped cleaning the nitrogenous compounds enough, as she should. What’s happening? The kidney sends a signal to the brain, we already know how, through macrophages. And the brain increases your blood pressure. What is happening to you? Where are you running right now? To the cardiologist! And say: “My blood pressure has increased.” And what does he say? “No problem. The best remedy…” And gives you a depressant, and your pressure is nailed. But the kidney has not received recovery, it cannot work. She asked the brain to add blood pressure to clear the normally nitrogenous compounds. They have not gone anywhere, where does she put them, she throws them into the intercellular space, they travel all over your body. Where do they accumulate? In the joints. Your knee joints hurt, your spine hurt. Where are you going? to an osteopath. He says: “Knees! I am a knee specialist! Here’s a nonsteroidal drug for you.” You start taking it. Where does a nonsteroidal drug hit in the first place? By the kidneys! The kidney is already screaming, screaming: “I am dying, I cannot perform the function! You will kill the body!” This is how she talks to her brain.
The brain raises blood pressure, where are you going? To the cardiologist. The cardiologist says: “Does it help? And here is the most powerful remedy! He gives you such a pressure depressant that it decreases in you, and what awaits you next? Stroke. Very little blood enters the brain, reducing the pressure to that extent. What should have been treated? Kidney! None of this would have happened at all. Do you understand?
I once talked with an American doctor, luminary, at one of the congresses. He began to say something to him, he said: “You know, Artem Mikhailovich, I don’t know what you are saying, I have no idea at all. I am the best middle ear specialist in the world. Here is the middle ear, I’m flying the best in the world. Do you want to know something about this?!” I say: “No, no, it seems not.” “But you know, I don’t know other organs, it somehow doesn’t relate to what I do.” Here’s what’s going on. And the future of this whole economy, of course, it must collapse in the first half, I even think, in the first twenty years of the new century, which is ours now. Somewhere in the thirtieth, fortieth year, medicine must undergo absolutely cardinal changes.
This is absolutely the most important innovation trend today. We must switch to treating by adjusting the human immunity. On the data, on the cause of the disease, which you cure will remove all other consequences, all symptoms.
Now, you just said about AIDS, and you know that we have scientists in Russia who treat AIDS in twelve days! That’s what I just said – I must be destroyed. Can you imagine what I’m aiming at, what an industry, what a huge one, I don’t know what it is, like human activity in the fight against AIDS. To all these conferences, to all these terrible hospices, to everything. And I say no to AIDS! No AIDS!

A person has a tenfold supply of immunity at birth, which is not used up. AIDS is a situation when, due to a virus, due to some other things, the human immune system is turned off. There is no concept of immunodeficiency! This is a lie! There is a concept of switched off immunity! How to turn on immunity in a person, that’s what it is to cure AIDS. How to turn it on – I can tell.
The fact is that when a child is born, here it is still in the womb, one of the organs in it is one third of the weight. Do you know what? Thymus. It is here (points to the chest) in a person, in an embryo.
The thymus gland is an organ that trains the immunity of a newborn child. Why does a child put everything in his mouth? You don’t have to punch him. It carries various infections and trains the immune system, and the more it carries, the better. By the age of twelve, the thymus gland becomes small, almost like this (shows the size of approximately a walnut). And we just don’t have it. This is a reduced organ, because it believes that: “I did everything, I trained the immune system. Now I’m not needed.” He reduces. But when we say I swear, where do we put our hand? From here, from here, right here (shows a place on his chest). Here she was the thymus gland – the main organ of man.
The whole world tried to synthesize thymus enzymes. Even, in my opinion, the Swiss received the Nobel Prize for the synthesis of some two or three sections of DNA. But no one has been able to make an effective chemical compound that would work like the thymus gland, teaching our immune system.
And then what? And then we suddenly noticed that there are animals, for example, a crocodile. But there is a stronger animal that does not get sick with anything, at all! There is an animal that can only be killed by a shot in the head or heart. If a bullet hits him, in any place, it crawls out of him and only a small scar remains. This animal does not get sick with anything all his life, lives with a huge thymus gland. Who? Seal! He lives in the ice, he dives to a depth of 200 m, he does not have caisson disease, he is all slashed by various propellers. He has no inflammatory processes at all.

And so our scientists, having taken this natural extract from the thymus gland of a seal, it turned out that it is suitable for a person. If, roughly speaking, a person is pierced with this extract, the immune system is restored. Immune response, immunity starts, immunodeficiency, the so-called, in quotation marks, passes. He is not! It just turns on at this moment what turned off for some reason.
Yes, it may still be necessary to remove the virus, or do something else, but AIDS is treated, does not heal, nor prolongs for many years, so that this poor AIDS patient comes to you every day and pays money. Do you understand?
It was all at a crossroads. This medicine is from Avicenna, from the ancient healers in general, yes, and she went the wrong way. She did not go in the direction of treating a person by a person himself.
Today, even Samuel Hannemann, the great man who invented homeopathy, was called a charlotte in Russia. What did Hannemann do? Hannemann said that like cures like. This is his formula, he bred fifty thousand times let’s say the pathogens of cholera, he drank the plague himself, and was cured.
How? And now we know how! When a small virus diluted fifty thousand times by this same pathogen enters the bloodstream, it is more effective, by the way, than ten thousand times dilutions. That’s what Hannemann did: he showed what homeopathy is, it’s grains, and there is some kind of small signal on it. You don’t need more, but it is enough for the macrophage to grab it, carry it to the brain and say: “You have the plague, urgently take action!” That’s what homeopathy is. Homeopathy heals, it is a real perfect technology that has been invented for centuries. Which was completely brainlessly destroyed in Russia by these decrees. But in fact, no, not for this reason, but for our doctors to prosper again, to treat longer, to sell more at the pharmacy. That’s what drives. Therefore, when we talked to this guy from Bayer, he says: “Artem Mikhailovich, modification of a drug, let’s say panadol, and we produce panadol plus, modification costs sixty-seventy million dollars to enter the market. But then we get seven hundred six hundred million!” Therefore, huge pharmaceutical giants, only they can bring new drugs to the market. Even whatever you come up with, you cannot go through all these stages without them, and even more so abroad, where all these places of registration are. Therefore, medicine has protected itself. Medicine has defended it, excuse me, but the business in the field of medicine has defended itself in such a way that it will be very difficult, practically difficult, to break this system. Do you understand? And so the Soviet Union, where medicine developed not based on the earnings of doctors, not based on this. Now we are already in the same field today. It is beneficial for doctors to treat, especially for polyclinics, where you can take money for some procedures.