What are the most effective medicines for lowering a fever. How do different fever reducers compare in terms of efficacy and safety. Which fever treatment options are best for children versus adults. When should you seek medical attention for a fever.

Understanding Fever and Its Treatment

A fever is the body’s natural response to infection or illness, typically defined as a body temperature above 98.6°F (37°C). While fevers can be uncomfortable, they often play a beneficial role in fighting off pathogens. However, there are times when reducing a fever becomes necessary for comfort or health reasons.

What constitutes a fever that requires treatment? For adults, a temperature of 103°F (39.4°C) or higher is generally considered concerning. For infants and children, the threshold may be lower, and it’s advisable to consult a pediatrician for guidance.

When to Treat a Fever

• The fever is causing significant discomfort
• There are signs of dehydration
• The fever is interfering with sleep or daily activities
• The patient has a pre-existing medical condition that may be exacerbated by fever

Over-the-Counter Fever Reducers: Acetaminophen vs. NSAIDs

The two main categories of over-the-counter (OTC) fever reducers are acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs). How do these medications differ in their mechanisms of action? Acetaminophen primarily works by affecting the body’s temperature regulation in the brain, while NSAIDs reduce fever by inhibiting prostaglandin production, which plays a role in inflammation and fever.

Acetaminophen: A Closer Look

Acetaminophen, also known as paracetamol in some countries, is a popular choice for fever reduction. What makes acetaminophen an effective fever reducer? It works by influencing the hypothalamus, the part of the brain responsible for regulating body temperature. This action helps to reset the body’s thermostat to a lower temperature.

Common brand names for acetaminophen include:

• Tylenol
• Feverall
• Mapap

Acetaminophen comes in various forms, including tablets, capsules, liquids, and suppositories, making it versatile for different age groups and preferences.

NSAIDs: Ibuprofen, Aspirin, and Naproxen

NSAIDs offer both fever-reducing and pain-relieving properties. How do NSAIDs work to lower fever? They inhibit the production of prostaglandins, which are involved in the inflammatory response and fever generation. This dual action makes NSAIDs effective for treating fevers associated with inflammatory conditions.

Common NSAID options include:

• Ibuprofen (Advil, Motrin)
• Aspirin (Bayer, Ecotrin)
• Naproxen (Aleve)

Comparing Efficacy: Which Fever Reducer Works Best?

Is one type of fever reducer more effective than others? Studies have shown that both acetaminophen and NSAIDs are generally equally effective in reducing fever. The choice often comes down to individual factors such as age, underlying health conditions, and potential side effects.

For children, acetaminophen and ibuprofen are commonly recommended. Aspirin is generally not advised for children due to the risk of Reye’s syndrome, a rare but serious condition.

Factors to Consider When Choosing a Fever Reducer

1. Age of the patient
2. Underlying health conditions
3. Other medications being taken
4. Duration of fever
5. Severity of symptoms

Proper Dosage and Administration of Fever Reducers

Administering the correct dosage of fever reducers is crucial for both efficacy and safety. How should one determine the proper dosage? For adults, follow the instructions on the medication label or consult with a healthcare provider. For children, dosage is typically based on weight rather than age.

Acetaminophen Dosage Guidelines

For adults, the maximum recommended daily dose of acetaminophen is 4,000 mg. It’s important to be aware of all sources of acetaminophen, as it’s often included in combination medications for colds and flu.

NSAID Dosage Considerations

NSAID dosages vary depending on the specific medication. For ibuprofen, adults can typically take 200-400 mg every 4-6 hours, not exceeding 1200 mg in 24 hours unless directed by a healthcare provider.

Potential Side Effects and Precautions

While fever reducers are generally safe when used as directed, they can cause side effects in some individuals. What are the most common side effects of acetaminophen and NSAIDs?

Acetaminophen Side Effects

• Nausea
• Stomach pain
• Headache
• Skin reactions (rare)

The most serious concern with acetaminophen is the potential for liver damage with high doses or long-term use.

NSAID Side Effects

• Stomach upset or bleeding
• Increased risk of heart attack or stroke (with long-term use)
• Kidney problems
• Allergic reactions

Individuals with certain health conditions, such as stomach ulcers or bleeding disorders, should exercise caution when using NSAIDs.

Alternative Fever Reduction Methods

While medication can be effective, are there non-pharmaceutical methods to reduce fever? Several home remedies and lifestyle adjustments can help manage fever symptoms:

• Staying hydrated with water, clear broths, or electrolyte solutions
• Resting and getting adequate sleep
• Using a cool compress on the forehead or taking a lukewarm bath
• Dressing in light, breathable clothing
• Maintaining a cool room temperature

These methods can be used in conjunction with medication or as standalone approaches for mild fevers.

When to Seek Medical Attention for a Fever

While most fevers can be managed at home, certain situations warrant medical attention. When should you consult a healthcare provider about a fever?

• Infants under 3 months with a rectal temperature of 100.4°F (38°C) or higher
• Children with a fever lasting more than 3 days
• Adults with a fever above 103°F (39.4°C) or lasting more than 3 days
• Fever accompanied by severe headache, stiff neck, confusion, or difficulty breathing
• Fever in individuals with compromised immune systems or chronic health conditions

These situations may indicate a more serious underlying condition that requires professional evaluation.

Fever Management in Special Populations

Certain groups require special consideration when it comes to fever management. How does fever treatment differ for these populations?

Infants and Young Children

Fever in infants and young children should be monitored closely. Acetaminophen is generally safe for infants, while ibuprofen is typically recommended for children over 6 months. Always consult a pediatrician for proper dosing and concerns.

Pregnant Women

Acetaminophen is usually considered safe during pregnancy, but NSAIDs should be avoided, especially in the third trimester. Pregnant women should always consult their healthcare provider before taking any medication.

Elderly Individuals

Older adults may be more susceptible to side effects from fever reducers. They may also have underlying health conditions that affect medication choice. Lower doses or alternative fever management strategies may be recommended.

Combining Fever Reducers: Benefits and Risks

Is it safe to combine different types of fever reducers? In some cases, alternating between acetaminophen and ibuprofen can be effective for managing persistent fevers, especially in children. However, this should only be done under the guidance of a healthcare provider.

What are the potential risks of combining fever reducers?

• Increased risk of side effects
• Potential for medication errors or overdose
• Masking of underlying conditions

It’s crucial to carefully track dosages and timing when using multiple medications.

Long-Term Considerations in Fever Management

While fever reducers can provide relief, it’s important to consider the broader picture of health and illness. What are some long-term considerations in fever management?

• Identifying and treating the underlying cause of the fever
• Monitoring for patterns of recurrent fevers
• Assessing the impact of frequent fever reducer use on overall health
• Developing a comprehensive approach to immune system support

Regular communication with healthcare providers can help ensure that fever management strategies align with overall health goals.

Emerging Research in Fever Treatment

The field of fever management continues to evolve. What are some recent developments or areas of ongoing research in fever treatment?

• Investigation of new antipyretic compounds with fewer side effects
• Studies on the role of fever in immune response and disease progression
• Research on personalized approaches to fever management based on genetic factors
• Exploration of the potential benefits of controlled hyperthermia in certain medical treatments

These areas of research may lead to more targeted and effective fever management strategies in the future.

Creating a Fever Management Plan

Developing a personalized fever management plan can help individuals and families respond effectively to fevers. What should a comprehensive fever management plan include?

1. A list of approved fever reducers and their appropriate dosages
2. Guidelines for when to initiate fever treatment
3. Non-pharmacological fever reduction strategies
4. Criteria for seeking medical attention
5. A record-keeping system for tracking fever patterns and medication use

Consulting with a healthcare provider can help in creating a plan tailored to individual needs and circumstances.

The Role of Fever in Immune Function

While fever reduction can provide comfort, it’s important to understand the role of fever in the body’s defense mechanisms. How does fever contribute to immune function?

• Enhances the activity of white blood cells
• Creates an inhospitable environment for certain pathogens
• Triggers the release of proteins that aid in immune response
• May help reduce the duration of some illnesses

This understanding can inform decisions about when and how aggressively to treat fevers, especially mild ones.

Fever Reducers and COVID-19

The COVID-19 pandemic has raised specific questions about fever management. How should fever reducers be used in the context of COVID-19?

While initial concerns were raised about the use of NSAIDs in COVID-19 patients, current evidence does not support avoiding these medications. Both acetaminophen and NSAIDs can be used to manage fever in COVID-19, following standard guidelines and precautions.

However, it’s important to note that fever reduction does not treat the underlying viral infection. Individuals with suspected or confirmed COVID-19 should follow current public health guidelines and seek medical advice as needed.

Technological Advances in Fever Monitoring

Advancements in technology have introduced new tools for fever monitoring. What are some innovative approaches to tracking body temperature?

• Wearable devices with continuous temperature monitoring
• Smart thermometers that connect to mobile apps for data tracking
• Non-contact infrared thermometers for quick and hygienic temperature checks
• Thermal imaging cameras for mass temperature screening

These technologies can provide more accurate and timely data, potentially improving fever management and early detection of illness.

Environmental Factors and Fever Management

The environment plays a significant role in body temperature regulation and fever management. How can environmental factors be optimized to support fever reduction?

• Maintaining appropriate room temperature (typically around 70-72°F or 21-22°C)
• Ensuring good air circulation
• Managing humidity levels to prevent excessive sweating or dehydration
• Using breathable bedding and clothing materials

Considering these factors can complement pharmacological approaches to fever reduction and improve overall comfort during illness.

Cultural Perspectives on Fever and Its Treatment

Attitudes towards fever and its management can vary across cultures. How do different cultural perspectives influence fever treatment approaches?

• Some cultures may view fever as a necessary part of the healing process and be less inclined to use fever reducers
• Traditional medicine practices in various cultures may incorporate herbal or other natural remedies for fever
• Cultural beliefs about the causes of fever can influence treatment-seeking behaviors
• Varying comfort levels with different forms of medication (e.g., preference for oral vs. rectal administration) may affect treatment choices

Healthcare providers should be sensitive to these cultural differences when discussing fever management strategies with patients from diverse backgrounds.

The Future of Fever Management

As our understanding of fever and its role in health and disease continues to evolve, what might the future hold for fever management?

• Development of more targeted antipyretic drugs with fewer side effects
• Integration of artificial intelligence in fever pattern recognition and prediction
• Personalized fever management protocols based on genetic and physiological factors
• Advancements in remote monitoring technologies for improved telemedicine capabilities
• Greater emphasis on the balance between fever reduction and supporting natural immune responses

These potential developments could lead to more nuanced and effective approaches to fever management in the coming years.

Best Fever Reducers: Options and Helpful Information

Best Fever Reducers: Options and Helpful Information

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Introduction

When you or your child has a fever, you want something that works quickly and works well. But with so many over-the-counter (OTC) medications available, it can be tough to know which one is best for you.

You can choose between two main types of OTC fever reducers: acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs include ibuprofen, aspirin, and naproxen. In general, no particular one of these fever-reducing drugs is better than the others. Instead, you should compare the drug forms, side effects, and other factors to choose a fever reducer that will work well for you or your child. Here’s what you need to know to make an informed decision.

Acetaminophen is a fever reducer and a pain reliever. It’s not fully understood how this drug works. Acetaminophen doesn’t decrease swelling or inflammation. Instead, it likely changes the way your body senses pain. It also helps cool your body to bring your fever down.

Forms and brand-name versions

Acetaminophen comes in several forms. These include:

• tablets
• extended-release tablets
• chewable tablets
• disintegrating tablets
• capsules
• liquid solution or suspension
• syrup

You take any of these forms by mouth. Acetaminophen is also available as a rectal suppository.

Common brand-name drugs that contain acetaminophen include Tylenol, Feverall, and Mapap.

Find acetaminophen online.

Side effects

When taken as directed, acetaminophen is generally safe and well-tolerated. However, in some cases, it can cause side effects such as:

• nausea
• vomiting
• trouble sleeping
• allergic reaction
• serious skin reactions, including severe rash

Warnings

Overdose

Because acetaminophen is found in many over-the-counter medications, it’s easy to take too much of it. That makes overdose a concern. You should not take more than 4,000 mg of acetaminophen in a 24-hour period.

This limit includes acetaminophen from all sources, including over-the-counter and prescription forms. Other common OTC drugs that contain acetaminophen include Alka-Seltzer Plus, Dayquil, Nyquil, Excedrin, Robitussin, and Sudafed. To be safe, avoid taking more than one product that contains acetaminophen at a time.

In case of overdose, call your local poison control center or 911 right away.

Liver damage

If you take too much acetaminophen, it can also cause liver damage. In severe cases, this can lead to liver failure, the need for a liver transplant, or death. Again, only take one medication that contains acetaminophen at a time, and always carefully follow the dosage instructions on the medication package.

Alcohol

Taking acetaminophen and drinking alcohol can also cause liver damage. In general, you should not take acetaminophen if you have three or more drinks that contain alcohol every day.

Extended fever or drug reaction

Stop taking acetaminophen if your fever gets worse or lasts more than three days. Also stop using it if you develop new symptoms such as skin redness or swelling. In these cases, call your doctor right away. They could be a signs of a more serious condition.

Drug interactions

Acetaminophen can interact with other drugs. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. Examples of drugs that can cause dangerous interactions when used with acetaminophen include:

• warfarin, a blood thinner
• isoniazid, a tuberculosis drug
• certain seizure medications such as carbamazepine and phenytoin

Nonsteroidal anti-inflammatory drugs (NSAIDs) include drugs such as:

• ibuprofen
• aspirin
• naproxen

NSAIDs help decrease inflammation, pain, and fever. They do this by blocking the body’s production of a substance called prostaglandin. This substance promotes inflammation and fever by causing the release of various chemical signals in your body.

Forms and brand-name versions

Ibuprofen

Ibuprofen comes in several forms. These include:

• tablets
• chewable tablets
• capsules
• liquid suspension

You take ibuprofen by mouth. Common brand-name products that contain ibuprofen include Advil and Motrin.

Shop for ibuprofen on Amazon.

Aspirin

Aspirin comes in these forms:

• tablets
• delayed-release tablets
• chewable tablets
• gum

You take any of these forms by mouth. Aspirin also comes as a rectal suppository. Common brand-name products that contain aspirin include Bayer Aspirin and Ecotrin.

Purchase aspirin here.

Naproxen

Naproxen comes in these forms:

• tablets
• delayed-release tablets
• capsules
• liquid suspension

You take naproxen by mouth. A common brand-name product that contains naproxen is Aleve.

Find naproxen online.

Side effects

The most common side effect of NSAIDs is an upset stomach. To help prevent stomach upset, take ibuprofen or naproxen with food or milk. You can take aspirin with food or a full glass of water.

NSAIDs can also have more serious side effects. The more serious side effects of ibuprofen or naproxen can include:

• stomach problems such as bleeding and ulcers
• heart problems such as heart attack and stroke
• kidney problems

The more serious side effects of aspirin can include:

• stomach problems such as bleeding and ulcers
• allergic reactions, with symptoms such as:
  • breathing trouble
  • wheezing
  • swelling of face
  • hives
  • shock

Warnings

Talk with your doctor before taking an NSAID if any of these warnings pertain to you.

History of heart disease

If you have a history of heart disease, you have increased risk of heart attack or stroke when taking ibuprofen or naproxen. The risk is still higher if you take more of these medications than directed or if you take them for a long time.

History of stomach ulcers or bleeding problems

If this applies to you, you have an increased risk of ulcers or bleeding when taking ibuprofen or naproxen. The risk is still higher if you:

• take these medications for a long time
• take other medications that contain NSAIDs
• take any blood thinner drugs or steroids
• are 60 years or older

Extended fever or drug reaction

There are several instances that indicate you should not continue to treat your fever with an NSAID. Stop taking NSAIDs if:

• your fever gets worse or lasts more than three days
• you develop any new symptoms
• you have skin redness or swelling
• you have ringing in your ears or hearing loss
• you have signs of a stomach bleed

Signs of stomach bleeding include:

• faintness
• blood in your vomit or vomit that looks like coffee grounds
• bloody or black stools
• stomach pain that does not improve

Stop taking the drug and call your doctor if you have any of these symptoms. These effects could be signs of a more serious condition.

Alcohol

If you have three or more drinks that contain alcohol per day, you’re at higher risk of ulcers or bleeding when taking ibuprofen, aspirin, or naproxen. Taking NSAIDs and drinking alcohol can cause severe stomach problems.

Problems in children

Avoid using aspirin in children and adolescents who are younger than 12 years and are recovering from chickenpox or flu symptoms.

Call your child’s doctor right away if your child has nausea and vomiting along with certain behavior changes. These include aggressive behavior, confusion, or loss of energy. These behavior changes may be early signs of a rare condition called Reye’s syndrome. If left untreated, Reye’s syndrome can be life-threatening.

Learn more about why aspirin and children don’t mix: Reye’s syndrome »

Drug interactions

NSAIDs can interact with other medications you may be taking. For example, NSAIDs can interact with:

• warfarin, a blood thinner
• celecoxib, another NSAID
• cyclosporine, a drug that weakens your immune system
• diuretics and other medications to treat high blood pressure

Fever reducers can affect people of different ages differently. Follow these age guidelines to help determine which fever reducer is best for you or your child.

Adults (ages 18 years and older)

Acetaminophen, ibuprofen, naproxen, and aspirin are generally safe for reducing fever in adults.

Children (ages 4-17 years)

Acetaminophen and ibuprofen are generally safe for reducing fever in children who are 4-17 years old.

Do not give aspirin to children unless your doctor says it’s okay.

Naproxen is safe in children ages 12 years and older. If your child is younger than 12 years of age, talk to your doctor before giving your child naproxen.

Children (ages 3 years and younger)

Acetaminophen and ibuprofen are generally safe for reducing fever in young children. However, be sure to talk to your child’s doctor first if your child is younger than 2 years.

Do not give aspirin to young children unless your doctor says it’s okay.

For infants younger than 3 months, call your doctor first before giving any medication.

When choosing a fever reducer, you have a few options. Acetaminophen, ibuprofen, naproxen, and aspirin can each help treat a fever. They each come with their own unique considerations, including what drugs they interact with, who they’re safe to treat, and their possible side effects. While there is no one best fever reducer, there may be a fever reducer that is the best option for you. Consider the information in this article carefully to make a healthy choice.

A:

Answers represent the opinions of our medical experts. All content is strictly informational and should not be considered medical advice.

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Last medically reviewed on July 29, 2016

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Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

• Acetaminophen – acetaminophen tablet, coated. (2012, December)
  dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e4cfbe12-d712-4ca6-8400-14eec2eca019
• Advil – ibuprofen sodium tablet, coated. (2015, September)
  dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5be198b8-396e-4b44-8819-e2e3b5d2ad0e
• Advil – ibuprofen capsule, liquid filled. (2016, June)
  dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1f01c10a-9434-91a4-2ee4-352315a6b610
• Aspirin 325 MG – aspirin tablet. (2016, February)
  dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=28c48336-c238-0141-e054-00144ff8d46c
• Motrin IB – ibuprofen tablet, film coated. (2015, September)
  dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5bca517f-94a5-428c-b716-80c6b0b86980
• U.S. National Library of Medicine. (2014, August). Acetaminophen
  nlm.nih.gov/medlineplus/druginfo/meds/a681004.html
• U. S. National Library of Medicine. (2016, June). Aspirin
  nlm.nih.gov/medlineplus/druginfo/meds/a682878.html
• U.S. National Library of Medicine. (2015, September). Ibuprofen
  nlm.nih.gov/medlineplus/druginfo/meds/a682159.html

Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available.

Current Version

Mar 8, 2019

Written By

University of Illinois-Chicago

Edited By

Juan Armstrong

Jul 29, 2016

Medically Reviewed By

Mohamed Jalloh

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Medically reviewed by Mohamed Jalloh — By University of Illinois — Updated on March 8, 2019

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Medication for fever: Options to consider

Two over-the-counter (OTC) options can help reduce a fever. They are nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil), and acetaminophen (Tylenol).

The Centers for Disease Control and Prevention (CDC) defines a fever as any temperature at 100.4ºF (38ºC) or above.

A fever is the immune system’s response to illness. It is an attempt to kill viruses and bacteria by raising the body’s temperature a few degrees.

While it is a natural process, it can be uncomfortable and become dangerous if a person’s temperature becomes too high.

Medications for fever do not treat the underlying condition causing the fever, but they can help reduce it and other symptoms of the illness.

People who are pregnant should consult a doctor before taking OTC medication for a fever. Parents and caregivers should also consult a doctor before administering any medications to a child.

This article outlines the medications available to treat a fever at home. It also discusses when to seek medical attention.

The following table provides a general overview of the medications a person can take to treat a fever. People should always check the medication label.

Ibuprofen is a type of NSAID sold under several brand names, including Advil and Motrin. It is a form of propionic acid and can help reduce fever as well as other symptoms, such as pain.

Depending on the dose, a person can get ibuprofen OTC at stores and pharmacies or via prescription. It comes in various forms, including tablets or capsules.

A 2022 article notes that people in their third trimester of pregnancy should not take ibuprofen.

Children can take ibuprofen, but parents and caregivers should speak with a pediatrician before giving them the medication.

Side effects

Side effects can include:

• constipation
• gas
• bloating
• diarrhea
• dizziness
• feeling nervous
• ringing in the ears

It can also cause nausea and vomiting.

Learn more about ibuprofen.

Naproxen is another type of NSAID, commonly sold under the brand name Aleve. Similar to ibuprofen, it is a form of propionic acid and can treat additional symptoms other than a fever.

A person can take naproxen sodium as a tablet or capsule. Liquid forms are available for younger children, although a parent or caregiver should talk with the child’s doctor first.

People who are in their third trimester of pregnancy should not take naproxen.

Side effects

Side effects can include:

• gas
• constipation
• dizziness
• headache
• excessive thirst
• drowsiness
• dizziness
• lightheadedness
• symptoms of a cold
• ringing in the ears
• sleeping difficulties
• hearing problems
• a burning or tingling sensation in the legs and arms

Learn more about naproxen.

Aspirin is another common form of NSAID that consists of acetylated salicylates. A common brand name is Bayer. This medication comes in several different formulas, including regular strength, and different forms such as tablets.

Caregivers should not give aspirin to children or teens without first consulting a doctor. A 2022 article notes an association between taking aspirin and the development of Reye’s syndrome, which can be fatal.

People who are pregnant should speak with a doctor before taking aspirin.

Side effects

Side effects include:

• nausea
• heartburn
• vomiting
• stomach pain

Learn more about aspirin.

Acetaminophen, commonly sold under the brand name Tylenol, is a non-opioid analgesic and antipyretic agent to treat pain and fever. Companies often add acetaminophen to other medications that treat allergies, colds, flu, and other medical conditions.

Acetaminophen is available OTC or as a prescription.

For teenagers and adults, it commonly comes in the form of tablets and capsules. Younger children may be able to take it in a liquid form, but caregivers should speak with a paediatrician first.

Side effects

The United Kingdom’s National Health Service (NHS) states that side effects are rare in adults and children if a person takes the correct dose.

However, in rare cases, a person can experience an allergic reaction.

In some cases, NSAIDs can lead to serious adverse effects, including problems affecting the liver, heart, and blood circulation.

Compared to prescription-strength medications, OTC NSAIDs typically cause fewer side effects.

Acetaminophen can lead to liver failure or other issues with the liver.

People can also experience an allergic reaction to fever-reducing medications. People should seek medical help if they experience:

• rash
• inflamed, peeling, or blistering skin
• itching
• hives
• hoarse voice
• difficulty swallowing
• difficulty breathing
• swelling of the face, tongue, throat, lips, hands, feet, eyes, lower legs, or ankles

A person should take fever-reducing medications only as a medical professional advises.

There are several formulas of NSAIDs and acetaminophen with differing doses. A person should follow the instructions on the packaging and pay attention to the maximum number of doses allowed in 24 hours.

When treating an underlying condition, a person should follow the doctor’s recommendations regarding how much to take and when to take it.

A person should also be mindful of other medications that may contain acetaminophen. Companies often mix it with other ingredients to create OTC medications for colds, flu, and other issues.

Can a person take acetaminophen and NSAIDs at the same time?

A person can take acetaminophen and ibuprofen at the same time.

Learn more about acetaminophen and ibuprofen.

A person may find that certain home remedies may help reduce their fever. Other options include:

• resting
• taking lukewarm baths
• drinking plenty of fluids
• wearing loose clothing

A fever breaks when a person’s temperature drops below 100.4ºF (38°C), but they may still feel ill due to the underlying condition. Dropping the fever can help alleviate some symptoms and help people feel better overall.

Learn more

Find out more about treating a fever:

• How to reduce a fever
• Treatment tips for breaking a fever
• What are the best home remedies for fever?
• How to bring down a fever in babies

A person should seek medical help if they are unable to lower the fever on their own or if they suspect a more serious underlying condition. They should also contact a doctor if:

• a person experiences worsening symptoms
• they have a weakened immune system
• they reach a fever of 104°F (40ºC) or higher
• they are concerned about a fever in a child or older adult

A person can take NSAIDs and acetaminophen to help treat a fever at home. These medications can also help to treat additional symptoms, such as pain.

A person should consult a doctor if their fever lasts longer than a few days, causes additional symptoms, or does not go down with medication.

How to reduce the temperature at home: antipyretic drugs

We talk about the main groups of antipyretic drugs: what are the pitfalls, what should not be used with certain drugs, why they are needed at all and whether it is possible to do without them.

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High fever is a frequent companion of diseases. When and how should it be brought down, and is it possible to do without drugs?

Contents of the article

Do not self-medicate! In our articles, we collect the latest scientific data and the opinions of authoritative health experts. But remember: only a doctor can diagnose and prescribe treatment.

An increase in temperature is a protective reaction of the body to serious external or internal stimuli, such as infections, poisoning with any toxins, inflammatory processes, and others. Normally, the temperature of the human body does not exceed 37.1 degrees Celsius, but during the period of illness it rises, and depending on how much, different types of temperature are distinguished:

• subfebrile – up to 37.9 degrees Celsius, does not require the use of antipyretics, usually accompanies sluggish inflammatory processes;
• febrile – from 38 to 38.9 degrees Celsius, the body actively fights irritants, many microorganisms cannot withstand such a temperature, so it should be brought down only if the patient clearly feels unwell;
• pyretic – from 39 to 41 degrees Celsius, the protective reaction is out of control, doctors recommend lowering this temperature so as not to overload the body systems;
• hyperpyretic – over 41 degrees, in this case the patient needs medical help, it is unlikely that he will be able to get off with conventional means. If the child has a temperature, an ambulance should be called already at 40 degrees.

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In general, raising the temperature is rather beneficial: firstly, as we have already said, many microbes do not like it, and secondly, it has been proven that in this way the body helps the immune system work – it hunts for irritants more efficiently. But, like everywhere else, there are nuances: in this mode, the load on the heart and nervous system may increase, and children may experience convulsions. The temperature still needs to be brought down, and not only when it is too high (38.5 degrees and above), but also earlier – if there is a possibility of convulsions or if the patient’s condition requires it. There are two main ways to reduce the temperature: take an antipyretic or use folk methods (however, the methods can be combined).

Best antipyretics for high fever

Almost all fever reducers are non-steroidal (meaning they are not hormonal) anti-inflammatory drugs (NSAIDs). In addition to fighting fever, they also reduce inflammation and reduce pain. Such a complex action allows the patient to feel better faster, because pains of various types are frequent companions of temperature. The only active substance commonly used in medicines with a different mechanism of action is paracetamol.

However, all antipyretics act in the same way: they affect the processes taking place in the hypothalamus, as a result of which less heat begins to form in the body, and more is released, due to which it, of course, cools down, and usually quite quickly – already after half an hour after taking a tablet, syrup or suppository, the temperature drops. Antipyretics are symptomatic treatment, they are not taken in courses, unlike other drugs, such as antibiotics. The purpose of fever-lowering drugs is to give temporary relief to a sick patient. At the same time, each of them has certain side effects, so when taking them, you need to weigh the pros and cons. Let’s talk about the main means used in Russia: about their action and some features. We note in advance that it is impossible to list all contraindications, side effects, interactions within the framework of this article, before using this or that drug, you need to read the instructions, and even better, consult a doctor who can weigh the risks for you personally. In addition, a particular person may have hypersensitivity to absolutely any drug or even be allergic to it, so even “banal” antipyretics should be used with caution at least the first time.

Paracetamol

There are many drugs with this active ingredient: panadol, calpol, tylenol, cefecon P, efferalgan – the list can be continued for a very long time. Paracetamol interacts with the hypothalamus, affecting the thermoregulatory center. This is one of the safest remedies, it can be used by both children and pregnant women, it helps to lower the temperature, thanks to it the pain subsides, but it does not fight inflammation very effectively. However, paracetamol is extremely common. The key recommendation of doctors when taking it is to follow the instructions in order to prevent an overdose.

Interaction: enhances the effect of coumarins, as well as drugs that harm the liver. Works worse with barbiturates. Some drugs may speed up or slow down absorption.

Contraindications: liver and kidney diseases, alcohol dependence.

Side effects: disruption of the circulatory system, kidneys, allergies.

Ibuprofen

Another drug that seems to be in all first aid kits. Demand for it is always stable (except perhaps during the coronavirus pandemic, for some time it was believed that ibuprofen should not be used for Covid-19 infection). Preparations with its content (a few examples) – nurofen, MIG, ibusan, bumidol. Ibuprofen, unlike paracetamol, also has an anti-inflammatory function – it weakens inflammatory processes, in addition, of course, it reduces the activity of thermoregulatory centers and drowns out pain. It works for a long time – up to 8 hours.

Interaction: reduces the effectiveness of acetylsalicylic acid (aspirin), enhances the action of an anticoagulant, should not be taken together with thrombolytics, barbiturates and ethanol, works worse with antacids, anesthetizes better in combination with caffeine.

Contraindications: Do not use in the 3rd trimester of pregnancy or while breastfeeding, gastrointestinal ulcers during exacerbation, asthma, kidney or liver dysfunction, certain diseases of the cardiovascular, circulatory system, skin.

Side effects: dysfunctions of ECT, liver, kidneys, allergies, reactions from the nervous system, circulatory system.

Acetylsalicylic acid

It is also the good old aspirin, as well as bufferin, mikristin, acylpyrine and others. Acetylsalicylic acid is useful not only for high temperature, inflammation and pain, but also for cardiovascular diseases. Like other non-steroidal anti-inflammatory drugs, it affects the centers of thermoregulation and pain sensitivity, reduces inflammation. This active substance primarily works as an antipyretic for adults.

Interaction: should not be used together with paracetamol, caffeine, ethanol, glucocorticoids, diuretics, diabetes drugs, works worse with antacids.

Contraindications: certain diseases of the cardiovascular system, gastrointestinal ulcers, acute liver or kidney failure. Do not take children, adolescents under 15 years of age, pregnant women with rare exceptions and breastfeeding.

Side effects: allergic reactions, disorders of the liver, gastrointestinal tract or kidneys, blood disorders.

Metamizole sodium

This name is not well known, but everyone knows the drug behind it – analgin (as well as baralgin M or optalgin). Basically, all these drugs are used as painkillers and sometimes anti-inflammatory, however, they also have antipyretic properties due to increased heat transfer. In many countries, the use of metamizole sodium has been questioned due to toxicity, but there is evidence that this toxicity occurs in people with a certain genetic defect.

Interaction: becomes stronger in combination with caffeine, codeine, barbiturates, toxic with antidepressants, oral contraceptives, should not be used with radiopaque agents. When injected, it must not be mixed with other drugs.

Contraindications: pregnancy, breast-feeding, impaired hematopoiesis, impaired liver and kidney function.

Side effects: allergy, hypotension, nephritis, blood diseases.

There are also a variety of medicines that combine several active ingredients at once. In this case, relief may come earlier, but, firstly, the side effects may be cumulative, and secondly, if the temperature needs to be brought down repeatedly, it may turn out that you have to choose between exceeding the daily dose (that is, the probable overdose) and the actual high temperature.

Paracetamol and ibuprofen-based single drugs are considered the most reliable and safe antipyretic drugs. If the regimen is followed, they have a minimum number of side effects, they can be used in the treatment of children, including infants, and these drugs have a lot of forms – syrups, suppositories, and tablets, so it is easy to choose a convenient method of use. Antipyretics are the easiest way to quickly reduce the temperature in an adult or child.

How to reduce the temperature at home without medication

If you suddenly find yourself somewhere where there is no pharmacy and you don’t have a supply of medicines with you, or you don’t want to use antipyretics for whatever reason, there are some folk methods of lowering the temperature. Perhaps they do this task more slowly than drugs specially designed for this purpose, but still they work.

• Rubbing with alcohol or vodka. Alcohol is diluted with water in a ratio of 1:1, vodka is used as is: moisten a cotton pad or a small towel with liquid and wipe the forehead, armpits, back of the hands. This should increase heat transfer (although some doctors doubt the effectiveness of the method). Not allowed for children.
• Rubbing with vinegar. Vinegar 9% is taken, diluted in proportion to a tablespoon per half liter of water. The solution can wipe the patient as a whole (for children – only the legs), for adults – make a compress on the head.
• Wiping with water.
• Tea with raspberries, cranberries, currants or juice from these berries also have anti-inflammatory and antipyretic properties. If we talk about decoctions – calendula, lime blossom, birch buds, oregano.
• Cool or cold plentiful drink.
• Cold water compresses.

Here are some more video tips:

If the temperature does not decrease with either folk remedies or antipyretic drugs, you should consult a doctor, this is especially important if the patient is a child, as children tolerate high temperatures worse. However, it is not useful for an adult to lie down for several days with a temperature of over 40 degrees, so medical assistance should not be neglected.

Temperature pills effective and inexpensive

THERE ARE CONTRAINDICATIONS. POSSIBLE SIDE EFFECTS. A SPECIALIST’S CONSULTATION IS NECESSARY. Antipyretic for adults Antipyretic for children Antipyretic suppositories Antipyretic syrups revna,

Diploma of pharmaceutical education: 105924 1197876, reg. number 30353

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Article contents

• To reduce temperature
• From high temperature
• Sources
• Ask an expert on the topic of the article

The temperature of a healthy person is kept within 36-37 degrees. When it rises, we begin to worry and try to bring it down. And alas, we often do it in vain.

An increase in temperature is a protective reaction of the body. This means that the internal mechanisms of immunity have turned on, aimed at fighting the disease and recovering. Of course, in the following situations, it is necessary to lower the temperature above 38 degrees:

• in infants under 2 months
• in children with a history of high fever accompanied by convulsions
• in children with lung and heart disease
• in adult patients who do not tolerate fever, have chronic diseases
• in the elderly

For other adults, according to the WHO recommendation, the temperature should be lowered only at values ​​above 38.5 degrees.

Pharmacist Natalya Zotina tells in her article about effective pills that lower the temperature in adults. Children are prescribed antipyretics, usually in the form of syrups and suppositories: Panadol syrup, Viburkol homeopathic suppositories, Cefekon D suppositories

Fever lowering

Two groups of drugs have the ability to lower fever: antipyretics and non-steroidal anti-inflammatory drugs (NSAIDs).

Antipyretic analgesics are known to all Paracetamol, Analgin and combination products containing them. Analgin effectively relieves pain and inflammation, but has an average antipyretic effect. In addition, the drug has a bad effect on the composition of the blood. Now tablets with analgin are practically not used for fever. But emergency care uses an analgin solution for injection in combination with diphenhydramine and papaverine for emergency help with high fever.

Another drug – Paracetamol – is considered one of the safest drugs and is approved for use in children from 3 months, pregnant and lactating women. It has a pronounced antipyretic and analgesic effect, helps with headaches. Effervescent soluble tablets with paracetamol are released to achieve a quick effect and ease of use. Paracetamol should not be combined with alcoholic beverages due to the high risk of toxic liver damage.

List of paracetamol tablets:

• Panadol
• Efferalgan
• Antigrippin (combination with ascorbic acid and chlorphenamine)
• Pentalgin NEO (combination with naproxen and caffeine)

All products Antigrippin

18 reviews

All products Panadol

20 reviews

All products Efferalgan

5 reviews

All products Pentalgin Neo

10 reviews

For high fever

Consider pills from the temperature from the second group – NSAIDs. These include drugs, which include acetylsalicylic acid and ibuprofen. They quickly reduce the temperature and have an anti-inflammatory and analgesic effect.

Aspirin or acetylsalicylic acid is a well-known and effective medicine. The antipyretic effect of aspirin occurs within 15 minutes after taking the pill. But the drug has many contraindications. Aspirin is prohibited for acute respiratory viral infections in children under 15 years of age, with bronchial asthma, with exacerbation of gastrointestinal diseases, liver failure and problems with blood clotting.

Ibuprofen is an antipyretic drug with proven efficacy and safety. It has a pronounced anti-inflammatory effect. Reduces temperature up to 8 hours. Children’s forms of ibuprofen are allowed for children from 3 months.

The use of the drug is not recommended in the I and II trimester of pregnancy, and in the III – it is prohibited. The drug, like aspirin, should not be used for diseases of the gastrointestinal tract.

Do not take ibuprofen and aspirin at the same time. This will not affect the antipyretic effect, but it will increase the risk of adverse reactions.

List of popular tablets containing acetylsalicylic acid

ibuprofen :

• Nurofen
• Nurofast
• MIG 400
• Ibuklin (combination with paracetamol)

Which tablets are better to take at high temperature? The World Health Organization recommends preparations with ibuprofen and paracetamol.

Patients sometimes ask if a person with a fever can use inhalers and nebulizers? Yes, you can. This reduces the time of illness, including the temperature period.

All products of Nurofen

15 reviews

All products of Aspirin

20 reviews

All products of Mig

20 reviews

All products of Upsarin Upsa

5 reviews

Most drugstore antipyretics are sold without a prescription.