What are the most effective fever reducers. How do acetaminophen and NSAIDs compare for fever treatment. Which fever medication is safest for children. When should you seek medical attention for a fever.

Understanding Fever and Its Treatment Options

A fever is the body’s natural response to infection or illness, characterized by an elevated body temperature. While fevers can be uncomfortable, they play an important role in fighting off pathogens. However, there are times when reducing a fever becomes necessary for comfort or health reasons.

The two main types of over-the-counter (OTC) fever reducers are acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs include ibuprofen, aspirin, and naproxen. Each has its own benefits and potential side effects to consider.

How do fever reducers work?

Fever reducers work by targeting the hypothalamus, the part of the brain that regulates body temperature. They help lower the body’s temperature setpoint, allowing the fever to subside. Additionally, many of these medications also provide pain relief, which can be beneficial when dealing with fever-related discomfort.

Acetaminophen: A Widely Used Fever Reducer

Acetaminophen, also known as paracetamol in some countries, is a popular choice for reducing fever and relieving pain. It works by altering the body’s pain perception and helping to cool the body, thus reducing fever.

Forms and brand names of acetaminophen

• Tablets
• Extended-release tablets
• Chewable tablets
• Disintegrating tablets
• Capsules
• Liquid solution or suspension
• Syrup
• Rectal suppositories

Common brand names include Tylenol, Feverall, and Mapap. Acetaminophen is also found in many combination medications for colds and flu.

Side effects and warnings for acetaminophen

When used as directed, acetaminophen is generally safe. However, potential side effects may include:

• Nausea
• Vomiting
• Sleep disturbances
• Allergic reactions
• Serious skin reactions (rare)

The most significant risk associated with acetaminophen is liver damage from overdose. It’s crucial to adhere to the recommended dosage and be aware of all sources of acetaminophen in your medications to avoid exceeding the 4,000 mg daily limit.

NSAIDs: Versatile Fever and Pain Relievers

Nonsteroidal anti-inflammatory drugs (NSAIDs) are another effective option for reducing fever. Unlike acetaminophen, they also have anti-inflammatory properties, making them useful for conditions involving inflammation.

Types of NSAIDs for fever reduction

1. Ibuprofen (e.g., Advil, Motrin)
2. Naproxen (e.g., Aleve)
3. Aspirin (not recommended for children due to the risk of Reye’s syndrome)

NSAIDs work by inhibiting the production of prostaglandins, which are involved in pain, fever, and inflammation processes in the body.

Potential side effects of NSAIDs

While generally safe when used as directed, NSAIDs can cause side effects, particularly with long-term use or in high doses:

• Stomach upset or ulcers
• Increased risk of bleeding
• Kidney problems
• Cardiovascular risks (with long-term use)
• Allergic reactions

People with certain medical conditions, such as stomach ulcers, bleeding disorders, or kidney disease, should consult their healthcare provider before using NSAIDs.

Comparing Acetaminophen and NSAIDs for Fever Reduction

When choosing between acetaminophen and NSAIDs for fever reduction, consider the following factors:

Effectiveness in reducing fever

Both acetaminophen and NSAIDs are effective in reducing fever. Some studies suggest that ibuprofen may be slightly more effective than acetaminophen, but the difference is generally not significant for most people.

Duration of action

Acetaminophen typically lasts 4-6 hours, while ibuprofen lasts 6-8 hours. Naproxen has the longest duration, lasting up to 12 hours.

Additional benefits

NSAIDs provide anti-inflammatory effects, which can be beneficial for conditions involving inflammation, such as arthritis or muscle sprains. Acetaminophen does not have anti-inflammatory properties but may be gentler on the stomach.

Safety considerations

Acetaminophen is generally considered safer for long-term use, particularly for those with stomach sensitivities or bleeding risks. However, it carries a risk of liver damage if overused. NSAIDs may be preferable for those with liver concerns but should be used cautiously in people with stomach, kidney, or cardiovascular issues.

Fever Reducers for Children: Special Considerations

Treating fevers in children requires extra care and attention to dosage and medication choice.

Is acetaminophen or ibuprofen better for children’s fevers?

Both acetaminophen and ibuprofen are considered safe and effective for children when used as directed. The choice often depends on the child’s age, weight, and any underlying health conditions.

Acetaminophen is approved for use in infants and children of all ages. Ibuprofen is approved for children 6 months and older. Aspirin should not be given to children or teenagers due to the risk of Reye’s syndrome.

Dosage guidelines for children

Always follow the dosage instructions on the medication label or as directed by a healthcare provider. Dosage is typically based on the child’s weight rather than age. Never give adult medications to children unless specifically instructed by a doctor.

Alternating acetaminophen and ibuprofen

In some cases, healthcare providers may recommend alternating between acetaminophen and ibuprofen for persistent fevers. This approach can provide more consistent fever control, but it should only be done under medical guidance to avoid medication errors or overdosing.

Natural Fever Reduction Methods

While medication can be effective for reducing fevers, there are also natural methods that can help manage fever symptoms:

• Rest and hydration: Adequate rest and increased fluid intake are crucial for recovery.
• Cool compresses: Applying a cool, damp cloth to the forehead can help lower body temperature.
• Lukewarm baths: A tepid bath can help cool the body, but avoid cold water as it can cause shivering, which raises body temperature.
• Light clothing and bedding: Dress in lightweight, breathable clothing and use light blankets to prevent overheating.
• Room temperature: Keep the room comfortably cool, around 70-72°F (21-22°C).

These methods can be used alongside medication or on their own for mild fevers.

When to Seek Medical Attention for a Fever

While most fevers can be managed at home, there are situations where medical attention is necessary:

For adults:

• Temperature above 103°F (39.4°C)
• Fever lasting more than three days
• Severe headache or neck stiffness
• Confusion or lethargy
• Difficulty breathing
• Persistent vomiting
• Signs of dehydration

For children:

• Any fever in infants under 3 months old
• Temperature above 102°F (38.9°C) in children 3-6 months old
• Fever lasting more than 24 hours in children under 2 years
• Fever above 104°F (40°C) in children of any age
• Signs of dehydration, such as dry mouth or no urination for 8-12 hours
• Unusual irritability or listlessness
• Fever accompanied by a rash

Always trust your instincts. If you’re concerned about a fever, don’t hesitate to contact a healthcare provider for advice.

Safe Use of Fever Reducers: Tips and Precautions

To ensure the safe and effective use of fever reducers, keep these important points in mind:

Read labels carefully

Always read the medication label for proper dosage instructions and potential drug interactions. Be aware of the active ingredients in combination medications to avoid accidental overdose.

Use appropriate measuring tools

For liquid medications, use the measuring device provided or a proper medicine syringe. Kitchen spoons are not accurate and can lead to dosing errors.

Avoid alcohol consumption

Alcohol can increase the risk of liver damage when combined with acetaminophen and may increase the risk of stomach bleeding with NSAIDs.

Be cautious with long-term use

Prolonged use of fever reducers, especially NSAIDs, can lead to side effects. Consult a healthcare provider if you need to use these medications for an extended period.

Store medications properly

Keep all medications out of reach of children and store them according to the instructions on the label. Check expiration dates regularly and dispose of expired medications properly.

By following these guidelines and understanding the differences between various fever reducers, you can make informed decisions about managing fevers for yourself and your family. Remember that fever is often a sign that your body is fighting an infection, so while reducing fever can provide comfort, it’s also important to address the underlying cause when necessary.

Best Fever Reducers: Options and Helpful Information

Best Fever Reducers: Options and Helpful Information

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Medically reviewed by Mohamed Jalloh — By University of Illinois — Updated on March 8, 2019

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Introduction

When you or your child has a fever, you want something that works quickly and works well. But with so many over-the-counter (OTC) medications available, it can be tough to know which one is best for you.

You can choose between two main types of OTC fever reducers: acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs include ibuprofen, aspirin, and naproxen. In general, no particular one of these fever-reducing drugs is better than the others. Instead, you should compare the drug forms, side effects, and other factors to choose a fever reducer that will work well for you or your child. Here’s what you need to know to make an informed decision.

Acetaminophen is a fever reducer and a pain reliever. It’s not fully understood how this drug works. Acetaminophen doesn’t decrease swelling or inflammation. Instead, it likely changes the way your body senses pain. It also helps cool your body to bring your fever down.

Forms and brand-name versions

Acetaminophen comes in several forms. These include:

• tablets
• extended-release tablets
• chewable tablets
• disintegrating tablets
• capsules
• liquid solution or suspension
• syrup

You take any of these forms by mouth. Acetaminophen is also available as a rectal suppository.

Common brand-name drugs that contain acetaminophen include Tylenol, Feverall, and Mapap.

Find acetaminophen online.

Side effects

When taken as directed, acetaminophen is generally safe and well-tolerated. However, in some cases, it can cause side effects such as:

• nausea
• vomiting
• trouble sleeping
• allergic reaction
• serious skin reactions, including severe rash

Warnings

Overdose

Because acetaminophen is found in many over-the-counter medications, it’s easy to take too much of it. That makes overdose a concern. You should not take more than 4,000 mg of acetaminophen in a 24-hour period.

This limit includes acetaminophen from all sources, including over-the-counter and prescription forms. Other common OTC drugs that contain acetaminophen include Alka-Seltzer Plus, Dayquil, Nyquil, Excedrin, Robitussin, and Sudafed. To be safe, avoid taking more than one product that contains acetaminophen at a time.

In case of overdose, call your local poison control center or 911 right away.

Liver damage

If you take too much acetaminophen, it can also cause liver damage. In severe cases, this can lead to liver failure, the need for a liver transplant, or death. Again, only take one medication that contains acetaminophen at a time, and always carefully follow the dosage instructions on the medication package.

Alcohol

Taking acetaminophen and drinking alcohol can also cause liver damage. In general, you should not take acetaminophen if you have three or more drinks that contain alcohol every day.

Extended fever or drug reaction

Stop taking acetaminophen if your fever gets worse or lasts more than three days. Also stop using it if you develop new symptoms such as skin redness or swelling. In these cases, call your doctor right away. They could be a signs of a more serious condition.

Drug interactions

Acetaminophen can interact with other drugs. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. Examples of drugs that can cause dangerous interactions when used with acetaminophen include:

• warfarin, a blood thinner
• isoniazid, a tuberculosis drug
• certain seizure medications such as carbamazepine and phenytoin

Nonsteroidal anti-inflammatory drugs (NSAIDs) include drugs such as:

• ibuprofen
• aspirin
• naproxen

NSAIDs help decrease inflammation, pain, and fever. They do this by blocking the body’s production of a substance called prostaglandin. This substance promotes inflammation and fever by causing the release of various chemical signals in your body.

Forms and brand-name versions

Ibuprofen

Ibuprofen comes in several forms. These include:

• tablets
• chewable tablets
• capsules
• liquid suspension

You take ibuprofen by mouth. Common brand-name products that contain ibuprofen include Advil and Motrin.

Shop for ibuprofen on Amazon.

Aspirin

Aspirin comes in these forms:

• tablets
• delayed-release tablets
• chewable tablets
• gum

You take any of these forms by mouth. Aspirin also comes as a rectal suppository. Common brand-name products that contain aspirin include Bayer Aspirin and Ecotrin.

Purchase aspirin here.

Naproxen

Naproxen comes in these forms:

• tablets
• delayed-release tablets
• capsules
• liquid suspension

You take naproxen by mouth. A common brand-name product that contains naproxen is Aleve.

Find naproxen online.

Side effects

The most common side effect of NSAIDs is an upset stomach. To help prevent stomach upset, take ibuprofen or naproxen with food or milk. You can take aspirin with food or a full glass of water.

NSAIDs can also have more serious side effects. The more serious side effects of ibuprofen or naproxen can include:

• stomach problems such as bleeding and ulcers
• heart problems such as heart attack and stroke
• kidney problems

The more serious side effects of aspirin can include:

• stomach problems such as bleeding and ulcers
• allergic reactions, with symptoms such as:
  • breathing trouble
  • wheezing
  • swelling of face
  • hives
  • shock

Warnings

Talk with your doctor before taking an NSAID if any of these warnings pertain to you.

History of heart disease

If you have a history of heart disease, you have increased risk of heart attack or stroke when taking ibuprofen or naproxen. The risk is still higher if you take more of these medications than directed or if you take them for a long time.

History of stomach ulcers or bleeding problems

If this applies to you, you have an increased risk of ulcers or bleeding when taking ibuprofen or naproxen. The risk is still higher if you:

• take these medications for a long time
• take other medications that contain NSAIDs
• take any blood thinner drugs or steroids
• are 60 years or older

Extended fever or drug reaction

There are several instances that indicate you should not continue to treat your fever with an NSAID. Stop taking NSAIDs if:

• your fever gets worse or lasts more than three days
• you develop any new symptoms
• you have skin redness or swelling
• you have ringing in your ears or hearing loss
• you have signs of a stomach bleed

Signs of stomach bleeding include:

• faintness
• blood in your vomit or vomit that looks like coffee grounds
• bloody or black stools
• stomach pain that does not improve

Stop taking the drug and call your doctor if you have any of these symptoms. These effects could be signs of a more serious condition.

Alcohol

If you have three or more drinks that contain alcohol per day, you’re at higher risk of ulcers or bleeding when taking ibuprofen, aspirin, or naproxen. Taking NSAIDs and drinking alcohol can cause severe stomach problems.

Problems in children

Avoid using aspirin in children and adolescents who are younger than 12 years and are recovering from chickenpox or flu symptoms.

Call your child’s doctor right away if your child has nausea and vomiting along with certain behavior changes. These include aggressive behavior, confusion, or loss of energy. These behavior changes may be early signs of a rare condition called Reye’s syndrome. If left untreated, Reye’s syndrome can be life-threatening.

Learn more about why aspirin and children don’t mix: Reye’s syndrome »

Drug interactions

NSAIDs can interact with other medications you may be taking. For example, NSAIDs can interact with:

• warfarin, a blood thinner
• celecoxib, another NSAID
• cyclosporine, a drug that weakens your immune system
• diuretics and other medications to treat high blood pressure

Fever reducers can affect people of different ages differently. Follow these age guidelines to help determine which fever reducer is best for you or your child.

Adults (ages 18 years and older)

Acetaminophen, ibuprofen, naproxen, and aspirin are generally safe for reducing fever in adults.

Children (ages 4-17 years)

Acetaminophen and ibuprofen are generally safe for reducing fever in children who are 4-17 years old.

Do not give aspirin to children unless your doctor says it’s okay.

Naproxen is safe in children ages 12 years and older. If your child is younger than 12 years of age, talk to your doctor before giving your child naproxen.

Children (ages 3 years and younger)

Acetaminophen and ibuprofen are generally safe for reducing fever in young children. However, be sure to talk to your child’s doctor first if your child is younger than 2 years.

Do not give aspirin to young children unless your doctor says it’s okay.

For infants younger than 3 months, call your doctor first before giving any medication.

When choosing a fever reducer, you have a few options. Acetaminophen, ibuprofen, naproxen, and aspirin can each help treat a fever. They each come with their own unique considerations, including what drugs they interact with, who they’re safe to treat, and their possible side effects. While there is no one best fever reducer, there may be a fever reducer that is the best option for you. Consider the information in this article carefully to make a healthy choice.

A:

Answers represent the opinions of our medical experts. All content is strictly informational and should not be considered medical advice.

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Last medically reviewed on July 29, 2016

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Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

• Acetaminophen – acetaminophen tablet, coated. (2012, December)
  dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e4cfbe12-d712-4ca6-8400-14eec2eca019
• Advil – ibuprofen sodium tablet, coated. (2015, September)
  dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5be198b8-396e-4b44-8819-e2e3b5d2ad0e
• Advil – ibuprofen capsule, liquid filled. (2016, June)
  dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1f01c10a-9434-91a4-2ee4-352315a6b610
• Aspirin 325 MG – aspirin tablet. (2016, February)
  dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=28c48336-c238-0141-e054-00144ff8d46c
• Motrin IB – ibuprofen tablet, film coated. (2015, September)
  dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5bca517f-94a5-428c-b716-80c6b0b86980
• U.S. National Library of Medicine. (2014, August). Acetaminophen
  nlm.nih.gov/medlineplus/druginfo/meds/a681004.html
• U. S. National Library of Medicine. (2016, June). Aspirin
  nlm.nih.gov/medlineplus/druginfo/meds/a682878.html
• U.S. National Library of Medicine. (2015, September). Ibuprofen
  nlm.nih.gov/medlineplus/druginfo/meds/a682159.html

Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available.

Current Version

Mar 8, 2019

Written By

University of Illinois-Chicago

Edited By

Juan Armstrong

Jul 29, 2016

Medically Reviewed By

Mohamed Jalloh

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Medically reviewed by Mohamed Jalloh — By University of Illinois — Updated on March 8, 2019

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10 Ways to Reduce Fever from a Cold or Flu │ Vicks

Do you or your loved one have a fever? The good news is you probably have nothing to worry about. Fevers are extremely common and often occur due to a virus like a cold or flu, though they’re more common in people who have the flu.^1,2 They usually occur when the body is working to fight an infection in order to protect itself.^3–5 As with other cold and flu symptoms, a fever is a sign that something out of the ordinary is going on in your body.

Fevers that are caused by cold viruses or flu viruses can last 3-4 days, and unfortunately, a fever—especially a high-grade fever (over 103°F)—can feel quite uncomfortable⁶. If you are suffering from a fever and want some relief, here are some tips for how to reduce a fever – at home or with medicine.

10 Things that Can Help to Lower a Fever

Home Remedies for Fever Symptoms

1. Rest

Activity can raise your body temperature. You need to rest in order to recover and reduce a fever. For an adult whose fever is 102°F (38.9°C) or lower, the recommendation is simply to rest and drink lots of fluids. Medication isn’t always necessary. Getting enough sleep can also help to support the integrity of your immune system, so your body can fight fever-causing viruses like a cold or flu.⁸

Call a doctor if your fever is accompanied by a severe headache, stiff neck, shortness of breath or other unusual signs or symptoms.

2. Hydration

Having a fever can cause fluid loss and dehydration. It’s important to drink plenty of fluids when you have a fever. Adequate fluid intake is often advised as part of a treatment plan for fever-inducing infections like the flu.⁷

3. A cool environment

Keeping the room temperature cool and sleeping with only a sheet or light blanket can help keep you cooler. If your child has a fever, adjust the temperature in the house or bedroom to help keep them cool. ⁹

4. Light clothing

When you want to break a fever, it’s also a good idea to dress in light clothing, as lighter clothing can have a cooling effect.¹⁰ It’s been reported that very warm clothing may increase a child’s body temperature even in the case that they are not ill.¹¹

5. Tepid sponging

Placing a cool, damp washcloth on your forehead and the back of your neck can help your fever symptoms feel better. You might also want to give yourself a sponge bath with cool water, focusing on high-heat areas like your armpits and groin. Normally, this method, known as tepid sponging, is done for about 5 minutes. Like staying in a cool environment and wearing light clothing, this physical measure for reducing a fever may not be as effective as fever-reducing medications.^12,13

Over-the-Counter Medicines that Reduce Fever

A fever is not a pleasant symptom to experience. The chills, shivering, and headaches can become uncomfortable enough that you want relief. Keep over-the-counter medicines on hand with active ingredients that can reduce fever. Acetaminophen, for example is an over-the-counter medication that is approved for use against fever, even in children.¹⁰

Acetaminophen is a commonly used drug for reducing fever that also relieves minor aches and pains.¹⁴ But you may find that when you have a cold or flu, there are more symptoms that you need relief from, like coughing or nasal congestion.

Many over-the-counter cold and flu medicines treat multiple symptoms, including fever. Make sure to identify what other symptoms you may be experiencing along with fever, if any, so you can get the relief you need. Keep reading for Vicks products that can help reduce fever, along with other common cold and flu symptoms.

6. Dayquil SEVERE

Dayquil SEVERE is a non-drowsy cold and flu symptom relief medicine for your worst cold symptoms. Along with acetaminophen to reduce fever, it also relieves chest congestion with an expectorant (guaifenesin), nasal congestion with a nasal decongestant (phenylephrine), and cough with a cough suppressant (dextromethorphan).

7. Nyquil SEVERE

Fever and other cold and flu symptoms like sneezing, and cough can make it harder to sleep and get the rest you need to fight off a virus. Like DayQuil, NyQuil SEVERE has acetaminophen to reduce fever. It also has an antihistamine to help with sneezing and runny nose symptoms, and dextromethorphan to suppress your cough so you can get a good night’s sleep.

8. Sinex SEVERE All-in-One Sinus LiquiCaps™

Some colds come with uncomfortable sinus symptoms—like sinus congestion, pressure, headache, and pain. That’s where Sinex comes in. Sinex SEVERE All-in-One Sinus LiquiCaps™ relieves those symptoms from the common cold or flu so you can breathe freely fast.

9. FluTherapy Daytime

You’ll likely spend time resting at home if you have a cold or flu. FluTherapy Daytime comes in a soothing hot drink form, with the powerful ingredients to relieve your cold and flu symptoms while you recover at home. Dissolve the contents of one packet into 8 oz. of hot water and stir briskly. Make sure to drink the entire medicated hot drink within 10-15 minutes. FluTherapy Daytime relieves nasal congestion, sore throat, body aches, fever, and cough from a cold or flu.

10. FluTherapy Nighttime

Like the daytime formula, FluTherapy Nighttime is a medicated hot drink with relief in every sip. It reduces your fever with acetaminophen and relieves other common cold and flu symptoms like runny nose. Be sure to take it at night when you’re ready to go to sleep, it will relieve your cough so you can rest and fight off the cold or flu virus causing your fever.

When to see a doctor

It is important to recognize that not all fevers are the same. While the U.S. Centers for Disease Control and Prevention (CDC) define a fever as a temperature at or above 100. 4°F (38°C), low-grade fevers that involve lower temperatures and more mild symptoms are often much less of a concern than high-grade fevers.¹⁵

While fevers can be beneficial because they can help to kill off problematic invading viruses, high fevers can be damaging to our bodies, so monitoring the level of your fever when you have one is important.⁴

It is generally recommended that you see a doctor if you are experiencing any of the following:¹⁶

• If your temperature reaches 104°F or higher.
• If you have fever or cough symptoms that improve, then get worse.
• If your fever is accompanied by a severe muscle pain, mental confusion, or any other out-of-the ordinary symptoms.

The fastest and most reliable way to determine if you have a fever and how significant that fever may be is to take your temperature with an easy-to-use at-home thermometer. Determining the severity of your fever can help you delineate what may be causing the fever and help you understand the best course of action to take to restore your health, and when to see your healthcare provider. ¹⁷

Fevers can occur for a variety of reasons but are often the result of a virus like a cold or flu. There are several things you can try to reduce your fever and relieve any other common symptoms. One category of these options is home remedies, such as ones that help to physically cool your body and bring your temperature down based on your external environment. Another category is over-the-counter medicines that can work by combatting fever-causing mechanisms in your body. It may also be beneficial to combine physical interventions with drugs that can help to break your fever.

Regardless of how you choose to address your fever, monitoring your fever is important for obtaining information regarding the underlying cause and severity of your condition. In cases of high or persistent fevers, or fevers accompanied by severe symptoms, you should seek medical attention.

Hopefully, you’ll now be able to reduce your fever associated with your cold or flu. For your other cold or flu symptoms, take a look at some great cold remedies and flu treatments—and get well soon!

1. What you need to know about infectious disease. nih.gov. https://www.ncbi.nlm.nih.gov/books/NBK209710/. Accessed June 9, 2020.

2. Chughtai AA, Wang Q, Dung TC, Macintyre CR. The presence of fever in adults with influenza and other viral respiratory infections. Epidemiol Infect. 2017;145(1):148-155. doi:10.1017/S0950268816002181

3. Torreggiani S, Filocamo G, Esposito S. Recurrent Fever in Children. Int J Mol Sci. 2016;17(4):448. doi:10.3390/ijms17040448

4. Soszyński D. [The pathogenesis and the adaptive value of fever]. Postepy Hig Med Dosw. 2003;57(5):531-554.

5. Moltz H. Fever: causes and consequences. Neurosci Biobehav Rev. 1993;17(3):237-269. doi:10.1016/s0149-7634(05)80009-0

6. Flu Symptoms & Complications. CDC.gov. https://www.cdc.gov/flu/symptoms/symptoms.htm. Accessed June 29, 2020.

7. Ghebrehewet S, MacPherson P, Ho A. Influenza. BMJ. 2016;355:i6258. doi:10.1136/bmj.i6258

8. Dimitrov S, Lange T, Gouttefangeas C, et al. Gα(s)-coupled receptor signaling and sleep regulate integrin activation of human antigen-specific T cells. J Exp Med. 2019;216(3):517-526. doi:10.1084/jem.20181169

9. Bertille N, Purssell E, Hjelm N, et al. Symptomatic Management of Febrile Illnesses in Children: A Systematic Review and Meta-Analysis of Parents’ Knowledge and Behaviors and Their Evolution Over Time. Front Pediatr. 2018;6:279. doi:10.3389/fped.2018.00279

10. Fever in children: How can you reduce a child’s fever? nih.gov. https://www.ncbi.nlm.nih.gov/books/NBK279453/. Published 2009. Accessed June 11, 2020.

11. Fever in children: Overview. nih.gov. https://www.ncbi.nlm.nih.gov/books/NBK279455/. Published 2013. Accessed June 15, 2020.

12. Meremikwu M& O-I-A. Physical methods versus drug placebo or no treatment for managing fever in children. Cochrane Database Syst Rev. 2003;2.

13. Purssell E. Physical treatment of fever. Arch Dis Child. 2000;82(3):238-239. doi:10.1136/adc.82.3.238

14. Warwick C. Paracetamol and fever management. J R Soc Promot Health. 2008;128(6):320-323. doi:10.1177/1466424008092794

15. Common Colds: Protect Yourself and Others. cdc.gov. https://www.cdc.gov/features/rhinoviruses/index.html. Accessed June 29, 2020.

16. Flu: What to Do if You Get Sick. cdc.gov. https://www.cdc.gov/flu/treatment/takingcare.htm. Accessed June 26, 2020.

17. Bartfai T, Conti B. Fever. ScientificWorldJournal. 2010;10:490-503. doi:10.1100/tsw.2010.50

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What is better for temperature ibuprofen or paracetamol

Today, such a symptom of colds as fever causes concern in almost every person. Therefore, in order to understand why it occurs and how to properly treat it, it is best to consult a doctor.

However, if the specialist has already prescribed ibuprofen or paracetamol to choose from, then you should carefully study these two drugs and understand which one brings down the temperature better.

What are antipyretics and what are their types

To reduce the temperature, there is a special group of drugs – antipyretics. These are symptomatic medicines that can help reduce a person’s body temperature when they are febrile.

Antipyretics are divided into two subgroups:

1. NSAIDs (non-steroidal anti-inflammatory drugs) . From the name itself it is already clear that these medicines are anti-inflammatory drugs that reduce inflammation in the body, due to which the temperature rises, and also have a pronounced analgesic effect. They are also used for fever.
2. Antipyretics . They have an antipyretic effect in a feverish state, but compared to NSAIDs, these drugs are less effective in relieving pain and do not affect inflammatory processes. Paracetamol is the main drug in this subgroup.

Now let’s look at the two main drugs, ibuprofen and paracetamol, which can be classified as antipyretic drugs.

Which is better for fever ibuprofen or paracetamol?

Paracetamol suppresses pain of various etiologies (headache, menstrual pain, toothache, muscle pain, joint pain), but, most importantly, it is considered an effective antipyretic drug. This drug relieves the symptoms of a fever. Paracetamol acts on the thermoregulatory center in the hypothalamus, resulting in a decrease in temperature.

It is mainly used for SARS and influenza. This drug is quite safe, so it is prescribed for both children and adults.

Paracetamol may reduce fever caused by acute viral infections. However, it does not have an anti-inflammatory effect, therefore it is powerless in microbial infections, in such situations it is better to use ibuprofen.

The advantages of paracetamol also include the fact that it can be taken by pregnant and lactating women, as well as children and the elderly. The likelihood of side effects of the drug is very small, so it is considered a safe drug. In addition, paracetamol can be combined with various medications.

Ibuprofen is a well-known and frequently used member of the group of non-steroidal anti-inflammatory drugs. It stops inflammatory processes in the body, has an analgesic effect and can reduce the temperature.

Ibuprofen has a complex effect: reduces temperature, relieves pain and reduces inflammation. This NSAID is preferable to take in the case when there is a need not only to reduce fever, but also to relieve inflammation and pain.

Please note! In cases where the body temperature has risen due to the fact that a person is nervous or in a state of acute stress (thermoneurosis), any antipyretic drugs will not have any effect, since there are no inflammatory processes in the body that trigger the temperature increase mechanism. This method is called “aspirin test” and allows you to determine the cause of the fever.

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What are the side effects of ibuprofen?

Common side effects of ibuprofen are:

• indigestion, mild heartburn, nausea, vomiting;
• bloating, gas, diarrhoea, constipation;
• dizziness, headache, nervousness;
• decreased appetite;
• mild itching or rash;
• ringing in the ears.

The drug in question has a large list of side effects and if it is taken incorrectly, there is a high probability of gastrointestinal disorders or abnormalities in the cardiovascular system. Therefore, it is not recommended for pregnant women, the elderly and patients with renal or hepatic insufficiency.

Is it possible to combine paracetamol and ibuprofen? So, first you need to drink one tablet of paracetamol, in the dosage prescribed by the doctor, and then after 6 hours, take ibuprofen, in the dosage prescribed by the doctor. This is necessary in order to reduce the toxic load on the liver that occurs when the dose of each of the drugs is increased. The sequence of taking both drugs every 6 hours allows you to reduce the temperature for several days in a row without interruption and at the same time protect yourself from hepatotoxicity.

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Conclusions: what to choose depending on the temperature – paracetamol or ibuprofen

Thus, both drugs, paracetamol and ibuprofen, reduce elevated body temperature. However, the first has fewer side effects and it reduces the temperature during fever, but has no effect on inflammatory processes, and the second is just as effective in reducing the temperature, and also has an anti-inflammatory effect and a more pronounced analgesic effect. Paracetamol is also less effective at suppressing pain than ibuprofen.

It is important to note that ibuprofen and paracetamol can be used in children, since both drugs do not cause Reye’s syndrome (a rare liver disease in children 4-12 years old), which aspirin can provoke.

That is, the main difference that determines the choice of the drug is whether it is necessary to relieve inflammation and pain. If necessary, then ibuprofen should be chosen, and if it is necessary to remove one temperature, then paracetamol.

Read also all the details about how to combine ibuprofen and paracetamol in order to get the expected effect and not harm your health.

Also, if you’re curious about the difference between imodium and loperamide, and which one is best for diarrhea, check out our new article on the subject.

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Doctors have named the best drug to reduce fever

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Doctors have named the best drug to reduce fever

Doctors have named the best drug to reduce fever – RIA Novosti, 04.03 .2021

Doctors named the best drug to reduce fever

Doctors from the Spanish University of Navarra told which drug is best to use to reduce fever. 20 minutes writes about it. RIA Novosti, 04.03.2021 9Madrid

2021-03-04T15:27

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MOSCOW, March 4 – RIA Novosti. Doctors from the Spanish University of Navarra told which drug is better to use to reduce the temperature. 20 minutos writes about this. The experts found that in case of elevated temperature, paracetamol and ibuprofen are most often used. However, they note that these drugs have different properties, and advise taking them depending on the symptoms. The doctors said that, unlike ibuprofen, paracetamol does not have anti-inflammatory properties. So, the experts explained that ibuprofen belongs to the group of nonsteroidal drugs, whose action is directed to suppress the synthesis of prostaglandins – substances responsible for the inflammatory response and pain. “Ibuprofen can be used to treat mild to moderate pain due to various causes, as well as high fever,” Cinfa Laboratories added. According to the Official College of Pharmacists of Madrid, this drug is indicated for mild to moderate pain, such as migraine , for the symptomatic treatment of fever, rheumatic conditions, or to relieve symptoms in non-rheumatic diseases. As for paracetamol, doctors have called it the ideal medicine for the treatment of mild to moderate pain accompanied by fever, for example, in flu-like diseases. Experts noted that paracetamol does not cause side effects effects compared to ibuprofen, however, overdose may damage other organs, such as the liver. Thus, experts conclude that both drugs are safe for the human body, but if the temperature is accompanied by inflammation and severe pain, it is recommended to give preference to ibuprofen.

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MOSCOW, March 4 – RIA Novosti. Doctors from the Spanish University of Navarra told me which drug is better to use to reduce the temperature. 20 minutes writes about it.

Experts have found that paracetamol and ibuprofen are the most commonly used agents for fever. However, they note that these drugs have different properties, and advise taking them depending on the symptoms.

Doctors stated that, unlike ibuprofen, paracetamol does not have anti-inflammatory properties.

Thus, experts explained that ibuprofen belongs to the group of non-steroidal drugs, whose action is aimed at suppressing the synthesis of prostaglandins – substances responsible for the inflammatory response and pain.

The doctor told how to strengthen the body during changes in temperature

February 1, 2021, 07:32

Cinfa Laboratories.

According to the Official College of Pharmacists of Madrid, this drug is indicated for mild to moderate pain such as migraine, for the symptomatic treatment of fever, rheumatic conditions or for the relief of symptoms in non-rheumatic diseases.