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Why do i hiccup a lot: Hiccups – Symptoms and causes

Hiccups – Better Health Channel

Summary

Read the full fact sheet

  • Hiccups, or hiccoughs, are involuntary sounds made by spasms of the diaphragm.
  • Hiccups are usually harmless and resolve by themselves after a few minutes.
  • In some cases, prolonged hiccups that last for days or weeks may be symptomatic of underlying disorders.

Hiccups, or hiccoughs, are involuntary sounds made by spasms of the diaphragm. The diaphragm is a large sheet of muscle slung beneath the lungs that, together with the intercostal muscles, causes us to breathe. The muscular spasm of these muscles sucks air into the lungs, and the quick inhalation makes a structure inside the throat (called the epiglottis) slam shut. (The epiglottis is a flap of tissue that closes over the windpipe during swallowing to prevent the inhalation of food, fluids or saliva.) This sharp closure of the epiglottis causes the characteristic ‘hic’ sound of hiccups.

Generally, hiccups resolve by themselves after a few minutes, but prolonged hiccups that last for days or weeks may be symptomatic of underlying disorders. Certain drugs, including epilepsy medications, can make a person more prone to hiccups.

Symptoms of hiccups

The symptoms of hiccups include:

  • A sharp contraction or spasm of the diaphragm that is felt just below the breastbone.
  • Air is involuntarily sucked into the throat.
  • The closing epiglottis makes a ‘hic’ sound.
  • Hiccups usually stop after a few minutes.

Cause of hiccups

The muscular activity of the diaphragm is controlled by nerves. Hiccups occur when particular stimuli trigger the nerves to send the diaphragm into spasms. It is not known why this occurs.

Triggers of hiccups

The cause of hiccups is often unknown and there may be no apparent trigger. Various triggers, particularly those that cause pressure on the diaphragm, are known to prompt an attack of hiccups in some people from time to time. Some of these triggers include:

  • Eating food too quickly
  • Hot or spicy foods
  • Indigestion
  • Overconsumption of alcohol
  • Fizzy drinks
  • Cigarette smoking
  • Stress
  • Bad odours
  • Pregnancy.

Self-help strategies

Hiccups are harmless and usually resolve by themselves in a few minutes. Some hiccup ‘cures’ include:

  • Hold your breath
  • Take deep breaths
  • Breathe into a paper bag
  • Eat a bit of fresh ginger
  • Suck on a lemon
  • Have a hot water and honey drink
  • Eat a spoonful of sugar
  • Drink a glass of water slowly
  • Eat ice
  • Gargle
  • Sit down and lean forward over your knees
  • Ask someone to give you a fright.

Hiccups may be symptomatic of disease

Hiccups that last for days, weeks or even years may be symptomatic of underlying disease. Certain lung or brain disorders can sometimes interfere with the functioning of the diaphragm and make the person prone to hiccups. Hiccups may also be a side effect of surgery or particular medications.

Some of the diseases, conditions and drugs that may prompt frequent or prolonged attacks of hiccups include:

  • Oesophagitis (inflammation of the oesophagus)
  • An overactive thyroid gland
  • Pleurisy (inflammation of the membrane surrounding the lungs)
  • Pneumonia (inflammation of the lungs)
  • Kidney disease
  • Brain damage, such as stroke or tumour, that affects the area of the brain which controls the diaphragm
  • Abdominal surgery
  • Chest surgery
  • Certain epilepsy medications
  • Nicotine gum

Medical treatment

Prolonged hiccups should be medically investigated. Treatment options may include:

  • Treatment for the underlying disorder
  • Changes to current drug dosages
  • Switching to another form of nicotine therapy
  • Anti-spasmodic drugs to calm the diaphragm
  • A tube inserted into the nose (nasogastric intubation)
  • A nerve block
  • Surgery, to sever some of the nerves servicing the diaphragm.

Where to get help

  • Your doctor

Things to remember

  • Hiccups, or hiccoughs, are involuntary sounds made by spasms of the diaphragm.
  • Hiccups are usually harmless and resolve by themselves after a few minutes.
  • In some cases, prolonged hiccups that last for days or weeks may be symptomatic of underlying disorders.

This page has been produced in consultation with and approved
by:

Hiccups – Better Health Channel

Summary

Read the full fact sheet

  • Hiccups, or hiccoughs, are involuntary sounds made by spasms of the diaphragm.
  • Hiccups are usually harmless and resolve by themselves after a few minutes.
  • In some cases, prolonged hiccups that last for days or weeks may be symptomatic of underlying disorders.

Hiccups, or hiccoughs, are involuntary sounds made by spasms of the diaphragm. The diaphragm is a large sheet of muscle slung beneath the lungs that, together with the intercostal muscles, causes us to breathe. The muscular spasm of these muscles sucks air into the lungs, and the quick inhalation makes a structure inside the throat (called the epiglottis) slam shut. (The epiglottis is a flap of tissue that closes over the windpipe during swallowing to prevent the inhalation of food, fluids or saliva.) This sharp closure of the epiglottis causes the characteristic ‘hic’ sound of hiccups.

Generally, hiccups resolve by themselves after a few minutes, but prolonged hiccups that last for days or weeks may be symptomatic of underlying disorders. Certain drugs, including epilepsy medications, can make a person more prone to hiccups.

Symptoms of hiccups

The symptoms of hiccups include:

  • A sharp contraction or spasm of the diaphragm that is felt just below the breastbone.
  • Air is involuntarily sucked into the throat.
  • The closing epiglottis makes a ‘hic’ sound.
  • Hiccups usually stop after a few minutes.

Cause of hiccups

The muscular activity of the diaphragm is controlled by nerves. Hiccups occur when particular stimuli trigger the nerves to send the diaphragm into spasms. It is not known why this occurs.

Triggers of hiccups

The cause of hiccups is often unknown and there may be no apparent trigger. Various triggers, particularly those that cause pressure on the diaphragm, are known to prompt an attack of hiccups in some people from time to time. Some of these triggers include:

  • Eating food too quickly
  • Hot or spicy foods
  • Indigestion
  • Overconsumption of alcohol
  • Fizzy drinks
  • Cigarette smoking
  • Stress
  • Bad odours
  • Pregnancy.

Self-help strategies

Hiccups are harmless and usually resolve by themselves in a few minutes. Some hiccup ‘cures’ include:

  • Hold your breath
  • Take deep breaths
  • Breathe into a paper bag
  • Eat a bit of fresh ginger
  • Suck on a lemon
  • Have a hot water and honey drink
  • Eat a spoonful of sugar
  • Drink a glass of water slowly
  • Eat ice
  • Gargle
  • Sit down and lean forward over your knees
  • Ask someone to give you a fright.

Hiccups may be symptomatic of disease

Hiccups that last for days, weeks or even years may be symptomatic of underlying disease. Certain lung or brain disorders can sometimes interfere with the functioning of the diaphragm and make the person prone to hiccups. Hiccups may also be a side effect of surgery or particular medications.

Some of the diseases, conditions and drugs that may prompt frequent or prolonged attacks of hiccups include:

  • Oesophagitis (inflammation of the oesophagus)
  • An overactive thyroid gland
  • Pleurisy (inflammation of the membrane surrounding the lungs)
  • Pneumonia (inflammation of the lungs)
  • Kidney disease
  • Brain damage, such as stroke or tumour, that affects the area of the brain which controls the diaphragm
  • Abdominal surgery
  • Chest surgery
  • Certain epilepsy medications
  • Nicotine gum

Medical treatment

Prolonged hiccups should be medically investigated. Treatment options may include:

  • Treatment for the underlying disorder
  • Changes to current drug dosages
  • Switching to another form of nicotine therapy
  • Anti-spasmodic drugs to calm the diaphragm
  • A tube inserted into the nose (nasogastric intubation)
  • A nerve block
  • Surgery, to sever some of the nerves servicing the diaphragm.

Where to get help

  • Your doctor

Things to remember

  • Hiccups, or hiccoughs, are involuntary sounds made by spasms of the diaphragm.
  • Hiccups are usually harmless and resolve by themselves after a few minutes.
  • In some cases, prolonged hiccups that last for days or weeks may be symptomatic of underlying disorders.

This page has been produced in consultation with and approved
by:

Why does a person hiccup?


  • Andrei85
    06/02/2006 17:13

    Answer

    First read article on this site and I love it. 🙂

    Reply

  • Dimidrol
    07/18/2006 17:19

    Answer

    Informatively written! I knew about the contractions of the diaphragm, but for the first time I learned about the fact that these contractions relieve the load from the damaged vagus nerve! Thanks for the detailed answer! I’m starting to like this site more and more!

    Reply

  • michus
    09/11/2006 09:22

    Answer

    But breathing into a bag, creating an excess of carbon dioxide, helps radically.

    Reply

    • Altolm
      michus 12.09.2006 16:09

      Answer

      In my childhood, at the age of 9-12, I used to hiccup for whole days in a row and nothing helped, except for a qualitative, unexpected fright. All the methods listed in the note did not work. Later, I found / collected several effective ways to deal with hiccups, but I have not heard of breathing into a bag, I’ll try. Thank you!
      By the way, I read the first effective way in the magazine “Chemistry and Life” – The way of ballerinas: put your hands behind your back, take them as far as possible (like on a rack), bend over as much as possible and drink cool water in small sips (here you will need an assistant). They will always help, but it is difficult to cope alone.
      There are methods associated with general or local relaxation, but experience is needed here.

      Reply

  • Gamble
    michus 23.09.2006 22:22

    Answer

    The package actually reduces the amount of oxygen by replacing carbon dioxide.
    But they are used not from hiccups, but from the so-called. hyperventilation, nervous strain.

    Reply

    • michus
      Gamble 25. 09.2006 22:22

      Answer

      But it helps me.

      Reply

    • rena
      Gamble 26.09.2006 16:43

      Answer

      in general, those who have hysteria are given to breathe into the bag. With frequent, shallow breathing, respiratory alkalosis (an imbalance of acid-base balance) is formed.

      Reply

  • Anna
    30.01.2007 21:50

    Answer

    Eating something sweet helps with hiccups, other methods are ineffective for me.

    Reply

  • Kirill N. Kravchenko
    19.02.2007 22:35

    Answer

    Judging by what is written here, these are questions of human anatomy. Sometimes there are also surgical cases.

    Reply

  • klinkoff
    04/01/2007 20:56

    Answer

    This theory is supported when there are structural changes in this area (hiatus), but there are other reasons as well. More often, hiccups of central origin, as a result of incorrect impulses of the respiratory center, which is well confirmed by the help option with the package. This allows you to “reload” the respiratory center, and achieve normal coordination of the respiratory muscles, to which the diaphragm belongs. A somewhat modified version of the “package”, but more effective from experience, is to hold the breath with a moderate amount of air in the lungs, do 10-15 squats, and then start to slowly inhale through the nose, avoiding sharp deep breaths, forming a normal rhythm and volume of breathing.

    Reply

  • alexsb
    28.04.2007 16:27

    Answer

    !

    Reply

  • alexsb
    28.04.2007 16:32

    Answer

    yes it’s all good! But what about when you are lying in bed in a relaxed position and suddenly this hiccups begin! And by the way, nothing except Corvalol helps. I also heard that a spasm can go to the stomach and heart, my grandfather once hiccupped for 2 days, nothing helped, and my grandmother didn’t know what to do, it’s good that they are educated people and there was Tebet medicine in the library in one of the sections there was information that it is necessary to paste well the inside of both hands from the wrist to the elbow, she did it and after 30 minutes everything calmed down! but for me personally it is Corvalol!

    Reply

  • popov
    06/14/2007 08:27

    Answer

    And where does this opinion come from, that if a small child hiccups, then he is cold or froze?

    Reply

  • entropy
    08/30/2007 18:42

    Answer

    And my child starts to hiccup when he laughs 😉 At least don’t laugh at all.
    And he hiccupped for a very long time (half an hour!) and very often when he was in my stomach (during the last months of pregnancy). Was there no way to help him at all?

    Reply

  • ayscha
    07/03/2008 12:36

    Answer

    And I often start hiccuping after laughing!! How can this be explained?? How can this vagus nerve be affected during laughter? 🙂

    Reply

  • Master
    10.07.2008 18:48

    Answer

    Hiccups, like stretching, are an unconditioned reflex of the body to its internal problems. Hiccups can be caused by obstruction of food from the stomach to the intestines. (When hiccups, the body turns the contents of the stomach, trying to push it into the intestines.)
    The causes of obstruction may be different, but, usually, hiccoughs are caused by malnutrition. Often hiccups are relieved by a couple of glasses of water. Water thins the contents of the stomach, helping it pass into the intestines.
    Hiccups can be caused by an infection that causes inflammation and ulceration in the stomach and intestines. Inflammation narrows the passage from the stomach to the intestines, which causes obstruction, and, as a result, hiccups.
    Infection gets into the stomach, usually from unwashed glasses. It starts in the saliva that we leave on the glass when we drink from it. Conclusion: you need to follow the rule of hygiene.
    In addition, boiled water suppresses the intestinal microflora, which allows an infection that does not meet competition to multiply in our body.
    Conclusion: you need to drink more water, and raw water.

    Reply

    • Form
      Master 21.09.2008 20:20

      Answer

      “boiled water suppresses the intestinal microflora … you need to drink more raw water” – complete nonsense

      Reply

      • Master
        Form 22.09.2008 12:16

        Answer

        Do you know the difference between boiled water and raw water?
        One weekend they show two programs about animals: “In the world of animals” and “dialogues about animals” by Ivan Zatevakhin, and in both they show the same monkeys – baboons.
        In the first broadcast, the zookeeper complains, complains that these monkeys are prone to infectious diseases (they have constant diarrhea), and they (the zookeepers) are forced to thoroughly wash food and give the monkeys boiled water to drink.
        In the second broadcast, the same baboons in nature at the equator drink from a “hoof” (from puddles that form in the tracks left by the cattle of local residents).
        Imagine that “broth” of different unicellular organisms in these puddles in order to understand the obvious contradiction.
        This is explained as follows: the monkeys that live in the zoo have an imbalance in the intestinal microflora, and the zookeepers are to blame for this, they are to blame for giving the monkeys boiled water.
        Why does boiled water cause dysbacteriosis?
        The fact is that: if you heat water to (approximately) 70C, then all the dissolved air will leave it. This is what boiled water differs from raw water, and it is the absence of dissolved air that leads to an imbalance in the microflora in the intestines, since not all the unicellular bacteria we need in the intestines are anaerobic bacteria.
        The gentleman, who introduced himself on the ‘Form’ forum, states:
        ‘”boiled water suppresses the intestinal microflora … you need to drink more raw water” – complete nonsense’, but at the same time he refused to answer this question of mine (about boiled water). Obviously – does not know the answer.
        Mister Form, you make statements, the categoricalness of which is based not on your qualifications as a scientist, but on a greatly inflated conceit.

        Reply

        • ursus russus
          Master 25.05.200913:51

          Answer

          Ie, for example, do you think hot tea causes dysbacteriosis?

          Reply

        • ursus russus
          Master 25.05.2009 13:54

          Answer

          Ie, for example, do you think hot tea causes dysbacteriosis?

          Reply

          • Master
            ursusrussus 05/26/200900:17

            Answer

            If you will consume exclusively boiled (and boiled) foods, then you are guaranteed dysbacteriosis. But take comfort – but the worms in your intestines will not start up, because they breathe with the skin, and if oxygen does not enter the intestines with food, then they will not be able to live in your intestines. If you have these parasites, then drink boiled water, and the worms will leave themselves.
            It is very harmful to eat food containing preservatives, because preservatives (very effectively) kill the intestinal microflora. Silver cutlery and dishes are also harmful, for the same reason.

            Reply

            • Seagull_JL
              Master 11.08.2009 23:07

              Answer

              The concept of dysbacteriosis is unscientific. It is absent in ICD-10. The rest of the conclusions in this post also have nothing to do with reality.

              Reply

            • djanubis
              Master 28.09.2009 16:30

              Answer

              Oddly enough, silver appliances only kill DISEASE-causing microbes.
              And if you have worms, then firstly don’t kiss your dog, and secondly, drink a tincture of hazelnut leaves and wormwood. As for doses, I don’t know.

              Reply

  • bazik
    04.01.2009 14:56

    Answer

    A wonderful section, I will definitely need to replenish it when I talk with the children more … =)

    I sometimes hiccup if I smoke. Don’t smoke though…

    Reply

  • Evgen.m
    24.07.2009 23:45

    Answer

    As a rule, hiccups only after excessive consumption of alcoholic beverages, only sleep helps.

    Reply

  • qwertyuiop
    31.01.2010 16:04

    Answer

    The dumbest answer!!!!!!!!!!!!!!!!!!!!11

    Reply

  • Saloed
    10. 02.2010 14:45

    Answer

    I tried almost all methods against hiccups, until (perhaps by accident) I found a method that was 100% effective – the gag reflex. Two fingers in the mouth, there is a strong tension (which I won’t say), which should push out the contents of the stomach, but I don’t bring it to vomiting and that’s it, the hiccups are gone. I’ve only used it on myself, I don’t know how it will work on others.

    Reply

  • samara
    27.01.2011 01:55

    Answer

    God, what nonsense. vagus nerve yes ..))
    but the matter is in the middle part of the brain, there is excitation to the reflex spasm of the diaphragm.

    ..as they say “it’s all in my head”

    Reply

  • brown fox
    13.12.2012 15:34

    Answer

    Origin of hiccups
    Human EZI has shown that the fetal diaphragm produces movements similar to hiccups. As a result, fluid circulation occurs. filling the lumen of future airways. The need for this is unknown, the authors of the study assume that in this way they are preparing for breathing after birth.
    It can also be assumed that hiccups in children, which disappear with age, are the result of a gradual but insufficient inhibition of the stem reflex that has become unnecessary, activated by various mechanical factors. This explains the effect described here with irritation of the vagus, and cases that do not fit into this scheme.
    In any case, this is how I roughly explain to students in my department of physiology of the 2nd medical school.

    Reply

  • Kostja
    11.09.2020 15:06

    Answer

    I read that tadpoles inherited hiccups – they quickly close their throats so as not to choke. Whom to believe?

    Reply

  • Write a comment

    Hiccups: what to do

    Hiccups is a non-specific disturbance of the function of external respiration, which occurs as a result of a series of convulsive jerky contractions of the diaphragm and is subjectively manifested by unpleasant short and intense respiratory movements. It occurs occasionally in healthy people for no apparent reason and is usually a harmless, quickly ending phenomenon.

    Figure 1. Mechanism of hiccups. Image: rob3000 / Depositphotos

    Under what circumstances does hiccups occur?

    Hiccups may occur under the following circumstances:

    1. General cooling (especially in young children), especially when intoxicated.

    2. When the stomach is overdistended (overfilled with food). According to experts, such involuntary muscle contractions may come from the esophagus. Swallowing problems and food getting stuck in the esophagus cause spasms where the esophagus meets the stomach.

    3. With irritation of the phrenic nerve. The so-called “normal” hiccups are manifestations of a nervous tic. This occurs under the influence of the phrenic nerve, which, for unknown reasons, transmits excitation to the muscles of the diaphragm. The result is uncontrollable spasms.

    Photo: actiongp / freepik. com

    Can hiccups be a symptom of disease?

    Hiccups can also be a symptom of certain diseases, for example, in the case of irritation of the diaphragm during an inflammatory process in the abdominal cavity. Sometimes it becomes long and painful. Hiccups occur with some diseases of the brain and spinal cord, and can also be observed with myocardial infarction, infectious diseases and mental agitation.

    What to do with prolonged hiccups?

    In cases of prolonged, persistent hiccups, you should consult a doctor who will determine its cause and prescribe treatment. With the development of renal failure, constant or intermittent hiccups may also be observed. It is the result of the development of an abscess or tumor in the chest, diaphragm or esophagus. In some people, hiccups occur due to psychological reasons, it resembles reactions with transient paralysis in soldiers who are afraid of battle. In such cases, hiccups are unconscious and reflect a desire to avoid very unpleasant events. Some individuals experience hiccups in the postoperative period, which may be a reaction to pain medications.

    What is the reason for this phenomenon?

    Despite significant advances in medicine over the years, there is still no reliable cure for these minor spasms that cause a person to emit obscene sounds, like a street boozer.

    Don’t worry, there are several ways to solve this problem.

    How to get rid of hiccups?

    Photo: superpicture / freepik.com

    To get rid of hiccups, you need to stop spasms of the diaphragm and esophagus. This can be done either by distraction or by breathing techniques. Usually this is sufficient.

    What if the hiccups still persist?

    Lemon will help get rid of hiccups. Photo: jenoche / freepik.com

    When your hiccups persist, you make great efforts to make them disappear. You focus on your chest and consciously tighten your diaphragm. But by straining and trying to suppress the next bout of hiccups you expect, you only complicate the situation. Below we recommend you more correct tricks.

    • Swallow a small amount of something bitter or sour. When something unusual enters the digestive system, spasms usually go away: try sucking on a piece of lemon.
    • Try to suppress the hiccups by reflex. Place your finger on the wall of the throat as if you were about to induce vomiting. However, in fact, you do not need to bring your actions to such an extent. In this way, you can interrupt the established hiccup rhythm.
    • Try to kill hiccups with water. If you drink a large glass of water in small sips at a measured pace, you can stop hiccups. In this way, food residues are washed off from the lower part of the pharynx and, possibly, their irritating effect on the nerve passing in this area is eliminated.
    • Drink water in an inclined position of the torso. The upside down position offers a completely new approach to the treatment of hiccups. Bend your torso over the sink and begin to drink water from a glass moved as far away from you as possible.
    • Use the sudden startle method, for example startle the victim of hiccups with a sudden pop of an inflated bag or a loud shout. This can instantly stop the spasm.
    • Try the folk method with thread. Hispanic South Texas residents use a popular technique to interrupt hiccups with a red thread or strip of cloth. They are tied around the child’s head in the forehead at the level of the bridge of the nose. Perhaps the child directs his eyes to the thread and thus switches his attention. And this is just what you need to stop hiccups.
    • Sweeten the pill. Sprinkle some granulated sugar on the back of the tongue and swallow it, you can stir a spoonful of granulated sugar in a small amount of beer and drink this mixture.
    • Hold on to your tongue. The next time you have hiccups, open your mouth wide, take your tongue, pull it slightly and hold it for a few seconds. This method of treating hiccups was preferred by President Kennedy’s personal physician.
    • Bet Money is a favorite remedy of some doctors and they say has never failed in cases of normal hiccups. When someone hiccups, take out the money, put it on the table, and make a bet with that person that he or she won’t be able to hiccup the next minute. This person can’t really hiccup another time without losing the bet.

    You can stop hiccups by drinking water in an inclined position of the torso. Photo: goffkein / freepik.com

    Once you stop trying to stop the hiccups, a whole host of other muscles come into play and the spasms disappear.

    In which cases should I get tested?

    Examination is necessary in the following cases:

    • if the hiccups last more than an hour;
    • if attacks of hiccups occur several times a day or several days a week;
    • if, in addition to hiccups, you have chest pain, heartburn, or trouble swallowing.

    How does the elimination of hiccups proceed in this case?

    If your hiccups are very frequent or persist for a long time, your doctor may order an x-ray after you take barium to look for any obstruction in your esophagus. To eliminate hiccups that are permanent and not associated with any mechanical obstruction in the esophagus, the doctor may prescribe certain medications, depending on what your disorders are related to.

    An interesting fact is that Charles Osborne of Anton, Iowa, USA, began to hiccup in 1922. He led a normal life, was married twice and had 8 children, and stopped hiccuping in 1990 (Guinness Book of Records).

    Marina Apryatkina

    Sources

    • Gou ZP., Zhao YL., Zou LL., Wang Y., Shu SQ., Zhu XH., Zheng L., Shen Q., Luo Z., Miao J ., Wang YS., Luo XD., Feng P. The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial. // Pharm Biol – 2021 – Vol59- N1 – p.484-493; PMID:33899689
    • Abbasi J. Data Leak Exposes Early COVID-19 Vaccine Manufacturing Hiccups. // JAMA – 2021 – Vol325 – N14 – p.1385; PMID:33847730
    • Martinez Paredes JF., Thompson CC., Rutt AL. Laryngeal Manifestations of Intractable Singultus. // Cureus – 2021 – Vol13 – N3 – p.e13730; PMID:33842108
    • Anwar SL., Avanti WS., Choridah L., Dwianingsih EK., Hardiyanto H., Aryandono T. Concurrent manifestations of Horner’s syndrome and esophageal metastasis of breast cancer: case report of a young woman after a period of non-adherence to treatment: a case report. // J Med Case Rep – 2021 – Vol15 – N1 – p.194; PMID:33836802
    • Alefishat E., Aloum L., Baltatu OC., Petroianu GA. The action of aripiprazole and brexpiprazole at the receptor level in singultus. // J Integr Neurosci – 2021 – Vol20 – N1 – p.247-254; PMID:33834710
    • Atiyat R., Veeraballi S., Al-Atiyat N., Chan KH., Slim J. A Rare Case Report of Persistent Hiccups as an Atypical Presentation of COVID-19.