Allegra drowsiness: When Allergy or Cold Medication Makes You Drowsy
When Allergy or Cold Medication Makes You Drowsy
Tips for Staying Alert
By Purvi Parikh, MD
In treating allergies or a cold with antihistamines, you may experience drowsiness, a common side effect of the medication.
How does this happen? Histamine is a chemical produced by the immune system to fight off allergens and germs. When there is a threat of allergies or infection (such as the common cold), histamine is even more active. In its search-and-destroy process, it can cause allergy or cold symptoms such as runny nose, coughing, sneezing and itch eyes. Antihistamine medications relieve these symptoms by blocking the unwanted effects of histamine.
Unrelated to the immune system, histamine is also produced in the brain, where it plays an important part in feeling awake. Antihistamines used to treat respiratory symptoms can get into the brain and interrupt this work, making you feel drowsy.
What can you do about drowsiness from allergy medicines?
Some antihistamines are less likely to cause drowsiness than others.
Reactions vary considerably from one person to another. What relieves your symptoms without making you sleepy may be different from what works for someone else.
When you find one that works for you, stick with it – check chemical ingredients and dosages before changing brands or generics. On the other hand, if one doesn’t work for you, try another type.
Does diphenhydramine (Benadryl®) make you sleepy? First-generation antihistamines such as diphenhydramine (Benadryl®) usually cause drowsiness because they are less likely to affect the histamine produced in the brain or have other unwanted effects in the brain. Currently, there is no non-drowsy Benadryl® on the market.
Non-drowsy allergy medicines do exist. Newer, second-generation antihistamines such as cetirizine (Zyrtec®), fexofenadine (Allegra®) and loratadine (Claritin®) – marketed as “nonsedating” – usually cause less drowsiness. An added benefit is that second-generation antihistamines last longer than Benadryl.
Allegra is generally the least sedating.
Nasal spray antihistamines are also somewhat less likely to make you sleepy, since they target nasal passages directly rather than sending medicine throughout your body in the bloodstream. These are available only by prescription.
Regular use of an intranasal corticosteroid is not only safe but also an effective way to reduce use of antihistamines. They take a few days to start working, so you need to be patient. Ask your doctor or pharmacist about using an antihistamine with an intranasal corticosteroid the first few days. Some intranasal corticosteroids are available over-the-counter, while others are available as prescription medication.
To avoid daytime drowsiness, take an antihistamine in the evening rather than in the morning. It may help you sleep, with drowsy effects wearing off by the next morning. Be aware that drowsiness can last longer than you might expect – and that some antihistamines can cause vivid dreams.
Don’t drink alcohol when taking antihistamines, as it will increase the sedation.
What about antihistamines in cold and flu medications?
What many people may not know is that cold and flu medicines marketed to treat runny nose and sneezing usually include first-generation antihistamines – the more sedating types. That’s because they are often better at treating cold symptoms and drying up runny nose than the newer types.
Because of their sedating effect, cold medicines with antihistamines are labeled for nighttime use. Take this labeling seriously, as some include medications like doxylamine that are more sedating than others. Check labels for dosages as well, as these may vary, even within brands.
More is not better – read labels carefully and take only as recommended. Don’t supplement a multi-symptom cold medication with another single-ingredient antihistamine.
Be smart, be aware of allergy medication side effects
Smart use of allergy medications – knowing how they treat symptoms of an allergic reaction, being aware of potential unwanted side effects and, most important, monitoring their effect on you and your health – is just one step toward controlling allergy and cold symptoms.
Even more important: knowing what you are allergic to and taking steps to prevent or reduce exposure.
If your allergy symptoms tend to last longer than two weeks or are not adequately controlled with over-the-counter medications, schedule an appointment with a board-certified allergist for a full diagnosis.
Antihistamines and intranasal corticosteroids are intended for symptom relief. If antihistamines or intranasal corticosteroids are causing side effects such as drowsiness or other problems, there are other treatment options your doctor can offer for relief from allergic reactions. These options include allergen immunotherapy and non-drowsy allergy medicines like second-generation antihistamines or nasal sprays.
Reviewed by:
Dennis Williams, PharmD, is an Associate Professor at the University of North Carolina Eshelman School of Pharmacy. He practices at UNC Medical Center with the pulmonary medicine medical service.
He has served as a member of the National Asthma Education Program Coordinating Committee and the National Asthma Educator Certification Board. He serves on Allergy & Asthma Network’s Board of Directors.
Allegra vs. Zyrtec: How Do They Differ?
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Introduction
Sneezing, runny nose, and itchy, watery eyes. This can only mean one thing: allergy season.
Seasonal allergies are typically caused by your body’s reaction to pollen, a substance produced by trees and other plants. When these allergies strike, your body combats them by creating the symptoms you so despise. When these occur, you may consider using an over-the-counter (OTC) medication to ease your symptoms.
Allegra and Zyrtec are two commonly used allergy drugs. Both are available in prescription forms as well, but this article only covers the OTC versions. Here’s a side-by-side comparison to help you decide if one of them is right for you.
The main active ingredient in Allegra is fexofenadine. The main active ingredient in Zyrtec is cetirizine. Both of these drugs are antihistamines.
Antihistamines work by blocking a substance called histamine in your body. Histamine is known for causing allergy symptoms.
Blocking it helps prevent symptoms of seasonal allergies or hay fever.
Allegra and Zyrtec are available OTC in many forms. The table below details the forms. For specific dosage information on either drug, read the product package carefully or talk to your doctor or pharmacist.
Allegra and Zyrtec may cause mild side effects that tend to go away as your body gets used to the drug. Most of these don’t call for medical attention. But tell your doctor if any side effects are especially bothersome or don’t go away. Call your doctor or seek medical attention if you experience serious side effects.
The tables below list examples of side effects of Allegra and Zyrtec. Both Allegra and Zyrtec can cause similar side effects. The main difference is that Zyrtec is more likely to cause drowsiness than Allegra.
Drug interactions
If you’re taking other drugs, you should talk to your doctor before using Allegra or Zyrtec. Either one can affect the way the other medications work in your body.
These interactions can increase or decrease the effect of the other medications, or of Allegra or Zyrtec. Interactions may also increase your risk of side effects from any drug you’re taking.
Zyrtec may interact with drugs such as theophylline.
Allegra may interact with drugs such as:
- ketoconazole
- erythromycin
- rifampin
- antacids
If you’re taking antacids such as Maalox or Mylanta, take Allegra a few hours before or after you take the antacid. These antacids contain aluminum and magnesium, which can prevent your body from absorbing enough Allegra. This can make Allegra less effective. By taking your antacid at a different time from when you take Allegra, you can reduce this interaction.
Conditions of concern
Allegra and Zyrtec may also not be safe for people with certain health issues. For example, you should talk to your doctor about how safe it is to use Allegra or Zyrtec if you have kidney disease.
If you have liver disease, you should also talk to your doctor before using Zyrtec.
Other warnings
Fruit juices such as grapefruit juice, orange juice, and apple juice can decrease the amount of Allegra that your body absorbs. This can make the drug less effective.
To avoid this interaction, wait at least 4 hours after drinking fruit juice before taking Allegra. Or, you can wait 2 hours after taking Allegra to drink fruit juice. Make sure you take Allegra tablets with water, not juice.
You should also avoid taking Zyrtec and Allegra with alcohol. Combining the drugs with alcohol can cause excessive drowsiness.
Allegra and Zyrtec treat the same symptoms and come in similar forms, but these drugs have a few key differences between them:
- You need to pay attention to what you drink with Allegra because fruit juices can affect how well it works.
- Zyrtec is more likely to cause drowsiness than Allegra.
- The effects of Zyrtec may last a few hours longer than the effects of Allegra.
Your doctor or pharmacist can tell you more about Allegra and Zyrtec and which drug may be right for you.
They can also give you advice on taking the drugs safely.
Shop for Allegra.
Shop for Zyrtec.
Allegra and Zyrtec are common over-the-counter drugs used to treat allergy symptoms. Both drugs are safe and effective, but studies show Zyrtec’s effects may last longer than Allegra’s. Zyrtec is more likely to cause drowsiness. Drinking fruit juices can make Allegra less effective.
What and how to treat allergies?
With various allergic symptoms – runny nose, conjunctivitis, urticaria, etc. – we, of course, resort to the help of antihistamines. But at the same time, we rarely think about their features: for example, to which generation this or that remedy belongs, what side effects it has. And it should.
Determining the diagnosis
Let’s start with what is currently known two generations of antihistamines . The first antihistamines began to be used in the 40-50s of the last century. These drugs initially had a number of serious side effects, which, however, did not prevent them from “gaining popularity” – the work on their creation was even awarded the Nobel Prize! 2
Meanwhile, medicine was advancing.
In the 1980s, 2nd generation antihistamines appeared. They acted faster, more efficiently and were deprived of a number of side effects. But, nevertheless, many representatives of first-generation antihistamines continue to be widely used, and this despite the fact that reports of undesirable consequences of their use appeared almost 60 years ago! 1
To this day, we continue to treat allergies with outdated remedies. Out of ignorance or “out of habit” – it doesn’t matter! Agree, if there are more modern and safe drugs, it is unreasonable to use their less successful predecessors, which can harm the health of you and your children.
Still in doubt? Let’s talk in more detail about the dangers of first-generation antihistamines, what advantages second-generation drugs have over them, and which of their representatives should be remembered.
Diagnosis established
“Search and neutralize” 2
Imagine: an allergen enters the body, an allergic reaction begins, during which histamine is released.
By binding to receptors, this substance causes swelling, redness of the skin, bronchospasm, difficulty in nasal breathing, so it is very important to block its action, stop the inflammatory reaction.
Histamine receptors are found in blood vessels, smooth muscles, the heart, tissues of the central nervous system, epithelium, and also in the brain. 7 In order to relieve allergy symptoms, it is enough to act on peripheral receptors. However, first-generation antihistamines also block receptors in the brain, resulting in a number of side effects:
– They act on the central nervous system, and therefore cause sedation – drowsiness, inhibition of reactions .
– Their action is not stable and durable, which makes it necessary to use high doses several times a day (up to 4-6 times) of these drugs. ( And this despite the fact that the therapeutic concentration is reached only after 2 hours! 3 ) As a result, when using these drugs, there is a possibility of a whole range of side effects: drowsiness, dizziness, lethargy, impaired coordination, inability to concentrate.
– They do not have selectivity (“targeting” action on histamine receptors), they also block other types of receptors, which can cause tachycardia, dryness of the nasopharynx and oral cavity, urinary retention, constipation, and visual impairment. The condition of bronchial asthma may even be aggravated (sputum viscosity increases) and cardiac arrhythmia may occur as a result of toxic effects on the heart. 1
– May be addictive, and with prolonged (more than 7-10 days) use, the therapeutic activity of the drug decreases.
It is clear that in diseases such as bronchial asthma, chronic urticaria and perennial allergic rhinitis, requiring long-term use of antihistamines, the use of first-generation drugs is highly undesirable. 2
Mistakes we make 1
Perhaps the biggest mistake of using 1st generation drugs is that many mothers give these drugs to babies before bed at night, hoping that the sedative effect will contribute to a deeper sleep of the child.
In the course of recent studies of the effect of 1st generation antihistamines on the functioning of the brain, it was proved that they cause unnatural sleep, disrupt the course of sleep phases! 1 The onset of REM sleep (necessary for memory formation and brain development) is delayed, its duration is reduced. The use of first-generation antihistamines often leads to daytime sleepiness, reduced daytime activity, and impaired brain function, which is especially dangerous when they are used in children.
It has also been proven that 1st generation drugs contribute to a significant decrease in the ability of schoolchildren to learn, impaired concentration and memory.
With the regular use of such funds, cognitive functions (the ability of the brain to perceive and process information) are seriously affected, and therefore there is a threat to the full intellectual development of the child.
A special study was conducted in the UK with 1,834 teenage students taking exams.
Among the students were those who suffered from allergic rhinitis. They were divided into two groups – those who were not treated with anything, and those who took first-generation antihistamines. For the former, the probability of “failing” the exam was 40%, for the latter – 70%. 1
In general, it becomes clear why many developed countries are raising the issue of limiting the use of first-generation antihistamines without a prescription. 2
So, if you see one of the following substances on the package or in the instructions, know that you have a 1st generation antihistamine in your hands: Diphenhydramine, chloropyramine, promethazine, dimethindene, clemastine, mebhydrolin, etc. . 2
New generation chooses… 2.3
What kind of allergy medications do we, modern people, need? Well, of course, those that:
– act quickly and efficiently;
– in therapeutic doses, they practically do not have a sedative effect;
– work even at a high concentration of histamine in the blood, without harming the body;
– suitable for the treatment of most allergic diseases, including chronic forms;
– practically do not affect the ability of children to learn and concentrate;
– contribute to improving the quality of life against the background of the current allergic disease.
It is these qualities that second-generation antihistamines have. These drugs include cetirizine (Zodak®), levocetirizine (Zodak Express®), and fexofenadine (Allegra).
These drugs can also be taken by children. Zodak® in the form of drops can be used in children from 6 months. 4 A Zodak® and Zodak Express® tablets are approved for use from 6 years of age. The effect of the drug lasts for 24 hours, so it is taken only once a day. 5
In addition, with seasonal allergic rhinitis and chronic urticaria, it is reasonable to prescribe Allegra. It is approved for use in children over 12 years of age and, like Zodak®, is taken only once a day. 6
As a conclusion – a small reminder.
For allergies:
– Always consult an experienced allergist;
– Do not be lazy to study this issue yourself. This will allow you to ask the right questions at the doctor’s appointment and understand the essence of the treatment prescribed for your child.
price of analogues of expensive antihistamines
Medicine and health
Scientists are still struggling with the causes of allergies. Researchers from Australia have identified a link between food allergies and a lack of vitamin D, and their colleagues from England argue that “sterility” is to blame – it is better to introduce the child to new foods as early as possible so that in the future the body does not mistake for an allergen, for example, peanut butter.
Ekaterina Tabatchikova
does not sneeze
Author profile
Unfortunately, allergies cannot be cured, but it is possible to deal with the symptoms that appear due to the “turning on” of histamine. This substance is active and causes familiar allergic reactions: cough, runny nose and itching.
How histamine works
Pharmacists divide allergy pills into two generations based on duration of action, effectiveness and effect on the central nervous system.
Separately, glucocorticosteroids are isolated – the funds of this group are usually produced in the form of gels, ointments and lotions.
The “third generation” of allergy pills is still reserved for fundamentally new drugs, the effect of which will differ from the second generation pills. The Russian Association of Allergists in its clinical guidelines also does not mention any generations, except for the first and second.
From each group, we took the most popular allergy pills and selected cheap analogues. We consider the benefit as in a grocery store: we compare prices for the mass of the active substance.
How to return medicines to the pharmacy
Attention! If the doctor has prescribed a medicine, specify the possibility of replacing it with another one, but with the same composition. Perhaps, in addition to the main active substance, auxiliary ones also play a role: in a substitute, they may be incompatible with other drugs used.
Analogs or synonyms?
In colloquial speech, people call analogues of drugs from different manufacturers, but with the same active ingredient.
Pharmacists and pharmacologists object: analogues are drugs with different active ingredients, but used to treat the same diseases. And drugs from different manufacturers with the same active ingredient are synonymous.
In this article, we use the word “analogue” in a general sense – as a medicine with the same substance, but cheaper. Pharmacists and pharmacologists, forgive us.
First generation antihistamines
First generation allergy tablets cause drowsiness by affecting the central nervous system. But they act instantly – this is important when an allergic reaction develops quickly.
How to choose an allergy medication
Suprastin
One of the most inexpensive and effective allergy medications. Suprastin acts for 4-6 hours, but long-term use causes tolerance to the drug – that is, over time it may not become as effective at the same dosage.
The active ingredient in Suprastin tablets is chloropyramine.
Chloropyramine tablets
| Cost | Price per 1 g | |
|---|---|---|
| Chloropyramine | 79 R for 20 tablets of 25 mg | 160 R |
| Suprastin | 252 R for 40 tablets of 25 mg | 252 P |
Chloropyramine
Cost
79 R for 20 tablets of 25 mg
Price for 1 g
160 R
Suprastin
Cost
25 2 R for 40 tablets of 25 mg
Price per 1 g
252 R
” Suprastin
Dimedrol
If you try, the sedative effect of Dimedrol can be used as a narcotic – that’s why pharmacists sell tablets only by prescription.
An analogue of “Dimedrol” in tablets is unlikely to be found: only gels and eye drops are produced with the same active ingredient. Therefore, a table of analogues will come in handy if you need to get rid of allergy symptoms and you know for sure that diphenhydramine will cope with this.
The active ingredient in Diphenhydramine tablets is diphenhydramine. 20 tablets of 50 mg cost 11 R – this is 11 R for 1 g.
Polynadim, eye drops
03
Cost
259 R per 20 g
Ophthalmoferon, eye drops
Cost
334 R per 10 ml
Sigida Duo, eye drops
Cost
412 R per 10 ml0004 Second generation antihistamines
Second generation antihistamines begin to work within two hours of ingestion and do not cause drowsiness.
But there is a danger: some substances of this group can disrupt the heart rhythm if taken with antifungal drugs or grapefruit juice.
Cetrin
Cetrin tablets are prescribed for allergic rhinitis, dermatitis and even Quincke’s edema. One tablet is valid for 24 hours. But “Cetrin” has cheap analogues that contain the same active ingredient.
The active ingredient in Cetrin tablets is cetirizine. 20 tablets of 10 mg cost 160 R – or 800 R for 1 year
Cetirizine R
Cost
280 R for 30 tablets of 10 mg
Price per 1 g
933 R
Zincet
Cost
114 R for 10 tablets of 10 mg
Price for 1 g
1140 Р
Soloneks, drops
Cost
253 Р for 20 ml at 10 mg/ml
Price for 1 g
1265 Р
Parlazin, drops
Cost
248 R per 20 ml 10 mg/ml
Price for 1 g
1250 R
Zyrtec
Cost
206 R for 20 tablets of 10 mg
Price per 1 g
1030 R
Cetrin
Levocetirizine
Medicines containing levocetirizine, begin to act within 12 minutes after administration – this is the best result among all second-generation antihistamines.
Levocetirizine itself and its analogues are devoid of anticholinergic side effects that other drugs of this group sin: it is difficult urination, dry mouth, CNS inhibition.
“Levocetirizine” costs 299 R for 10 tablets of 5 mg – or 5980 R for 1 year.
481 R for 30 5 mg tablets
Suprastinex
Cost
436 R for 14 5 mg tablets
Price per 1 g 9Price per 1 g 2 3334 R
Glenset
Cost
584 R for 14 tablets of 5 mg
Price for 1 g
8339 R
Ksizal
Cost
660 R for 14 tablets of 5 mg
9000 2 Price per 1 g
9424 R
Levocetirizine
Loratadine
One of the most popular allergy remedies.
It is more effective than first-generation drugs, has no sedative effect and practically does not interact with other drugs.
The active ingredient in loratadine tablets is loratadine. 10 tablets of 10 mg cost 53 rubles – or 530 R for 1 year
Clarisence
Cost
144 R for 30 tablets of 10 mg
Price for 1 g
479 R
Lorahexal
Cost
53 R for 10 tablets of 10 mg
Price per 1 g
530 R
Claritin
Cost
228 R for 10 tablets of 10 mg
Price for 1 g
2280 R
Claridol
Cost
197 R for 10 tablets of 10 mg
Price for 1 g
1970 R
Lomilan
Cost
143 R for 10 tablets of 10 mg
Price per 1 g
1430 R
Loratadin
Kestin
This drug works 48 hours, so it is often taken during flowering or “just in case” before dinner in an exotic country..png)
The analogue of “Kestin” in terms of the active substance – ebastine – is the only one, but it costs less.
The active substance in Kestin tablets is ebastine.
Ebastine tablets
| Cost | Price per 1 g | ||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Espa-bastin | 265 R for 10 tablets of 10 mg | 2650 P | |||||||||||||||||||||||||||||
| Kestin | 375 R for 10 tablets of 10 mg | 3750 P |
| Cost | |||
|---|---|---|---|
| Acrystal | 249 R for 20 ml, 1 mg/ml | ||
| Fenistil | 456 R for 20 ml at 1 mg/ml | Cost | Price per 1 g |
| Desloratadine | 136 R for 10 tablets of 5 mg | 2720 P | |
| Desal | 242 R for 10 tablets of 5 mg | 4840 R | |
| Blogir-3 | 236 R for 10 tablets of 5 mg | 4720 R | |
| Lordestin | 358 R for 10 tablets of 5 mg | 7160 P | |
| Ezlor solution | 287 R for 10 tablets of 5 mg | 5740 Р | |
| Nalorius | 350 R for 10 tablets of 5 mg | 7000 R |
Desloratadine
Cost
136 R for 10 tablets of 5 mg
Price per 1 g R
Cost
242 R for 10 tablets of 5 mg
Price per 1 g
4840 R
Blogir-3
Cost
236 R for 10 tablets of 5 mg
Price for 1 g
4720 R
Lordestin
Cost
358 R for 10 tablets of 5 mg
Price for 1 g 9 0003
7160 R
Ezlor Solution
Cost
287 R for 10 tablets of 5 mg
Price for 1 g
5740 R
Nalorius
Cost
350 R for 10 tablets of 5 mg
Price per 1 g
7000 R
Erius
Feksadin
“Fexadin” perfectly copes with allergic rhinitis and urticaria.
Begins to act within an hour after ingestion and releases breath for at least 12 hours.
The active ingredient in Feksadin tablets is fexofenadine. 10 tablets of 180 mg cost 372 R – or 206 R for 1 year
Price per 1 g
R
Bexist-sanovel
Cost
702 R for 20 tablets of 180 mg
Price for 1 g
192 R
Allegra
Cost
595 R for 10 tablets of 180 mg
Price per 1 g
330 R
Feksadin
Glucocorticosteroids
These drugs do not work immediately, and after 4-6 hours. Glucocorticosteroids for internal use will help stabilize blood pressure by releasing your own adrenaline, and for external use – in the form of drops and ointments – get rid of annoying allergy symptoms.
Description of the group “Glucocorticosteroids” in the register of medicines of Russia
Flixonase
Flixonase spray can be used in children from 4 years old, but not longer than 2 months. The effect will appear within 2-4 hours after the first “puff”: the pain in the paranasal sinuses, nasal congestion, sneezing, itching in the nose and watery eyes will go away.
The active ingredient in Flixonase spray is fluticasone.
Flixonase analogs
| Analog | Cost |
|---|---|
| Nazarel | 376 R for 120 doses of 50 mcg |
| Flixotide | 697 R for 120 doses of 50 mcg |
| Avamis | 773 R for 120 doses of 27.5 mcg |
Nazarel
Cost
376 R per 120 doses of 50 mcg 002 Cost
697 R for 120 doses of 50 mcg
Avamys
Cost
773 R for 120 doses of 27.
5 mcg
Flixonase
Prednisolone
The World Health Organization has included Prednisolone in the list of essential medicines. There it is listed as an emergency drug for anaphylaxis, allergies, and also as a cure for Hodgkin’s and Burkitt’s lymphomas, acute lymphoblastic leukemia.
True, finding these inexpensive pills in pharmacies is not easy: the Ministry of Health could not agree on a price with manufacturers, so tenders for the purchase of Prednisolone failed. There are no closest analogues of “Prednisolone” with the same active ingredient in pharmacies – “Medopred” and “Decortin” also disappeared from the shelves.
How to save money at the pharmacy
All that remains for us is to choose pills that contain methylprednisolone: this substance works in the same way as prednisolone.
The active ingredient in Prednisolone tablets is prednisolone.
Analogues of Prednisolone
| Analogue of | Cost |
|---|---|
| Metipred, the active ingredient is methylprednisolone | 323 R for 30 tablets of 4 mg |
| Solu-medrol, active substance — methylprednisolone | 373 R for 250 mg of lyophilisate for solution preparation |
Metipred, active ingredient – methylprednisolone
Cost
323 R for 30 tablets of 4 mg medrol, active ingredient – methylprednisolone
Cost
373 R for 250 mg of lyophilisate for preparation solution
Prednisolone
Allergy tablets without analogues
Some medicines have no analogues or have been completely discontinued.
For example, the substitute and analogue of “Tavegil” was “Rivtagil” – a drug with the same active ingredient clemastine. But since 2006, the only tablets containing clemastine have been Tavegil, so it will not be possible to find a full-fledged replacement for them.
Allergy tablets without analogues
| Preparation | Active ingredient | Why there is no analogue |
|---|---|---|
| Tavegil | Clemastine | The only drug with this active ingredient |
| Diazolin | Mebhydrolin | The only drug with this active ingredient |
| Pipolfen | Promethazine | The only drug with this active ingredient |
| Erespal, epistat | Fenspiride | The active substance fenspiride was recognized as dangerous and withdrawn from the market |
Tavegil
Active ingredient
Clemastine
Why there is no analogue
The only drug with this active ingredient
9 0021 Diazolin
Active ingredient
Mebhydrolin
Why there is no analogue
The only drug with this active ingredient
Pipolfen
Active ingredient
Promethazine
Why there is no analogue
The only drug with this active ingredient
Erespal, epistat
Active substance
Fenspiride
Why there is no analogue
Day the active substance fenspiride was declared dangerous and withdrawn from the market
We have other articles that will help you save on medicines:
- Cheap analogues of expensive liver medicines.
