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Allergic reaction to xanax: RxList Page Not Found


Common and Rare Side Effects for Xanax oral

COMMON side effects

If experienced, these tend to have a Severe expression i

Sorry, we have no data available. Please contact your doctor or pharmacist.

If experienced, these tend to have a Less Severe expression i

  • altered interest in having sexual intercourse
  • drowsiness
  • low energy

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • a type of abnormal movement disorder called dyskinesia
  • trouble breathing

If experienced, these tend to have a Less Severe expression i

  • confusion
  • abnormal sexual function
  • excessive saliva production
  • constipation
  • pain with menstruation
  • premenstrual syndrome
  • a problem with menstrual periods
  • inflammation of the skin due to an allergy
  • joint pain
  • muscle pain
  • pain in the arms or legs
  • dizziness
  • difficulty sleeping
  • loss of muscle coordination
  • numbness
  • a skin rash
  • decreased appetite
  • weight gain
  • weight loss
  • changes in appetite
  • headache
  • rapid deep breathing
  • nausea and vomiting
  • diarrhea
  • nervousness
  • a feeling of pins and needles on skin
  • low energy and weakness
  • a sensation of feeling warm
  • deep sleep or sleep for long periods
  • abnormal dreams
  • a change in the ability to pay attention
  • anxious feelings

RARE side effects

If experienced, these tend to have a Severe expression i

  • manic behavior
  • addiction to a drug
  • low blood pressure
  • decreased lung function
  • liver failure
  • damage to the liver and inflammation
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • seizures
  • abnormal liver function tests
  • a type of allergic reaction called angioedema

If experienced, these tend to have a Less Severe expression i

  • a high prolactin level
  • a form of mania that has a lower severity of symptoms
  • nightmares
  • blurred vision
  • a change in vision
  • stuffy nose
  • dry mouth
  • indigestion
  • enlarged breasts
  • breastmilk production not associated with childbirth or nursing
  • itching
  • backache
  • muscle spasm
  • muscle weakness
  • cramps
  • difficulty concentrating
  • memory loss
  • sensation of spinning or whirling
  • excessive sweating
  • muscle tremors
  • muscle twitching
  • fluid retention in the legs, feet, arms or hands
  • slurred speech
  • a type of speech disorder called dysarthria
  • heart throbbing or pounding
  • chest pain
  • difficult or painful urination
  • an inability to completely empty the bladder
  • generalized weakness
  • a feeling of general discomfort called malaise
  • intense abdominal pain
  • abnormal muscle movements
  • an increased interest in having sexual intercourse

Xanax side effects, interactions, and warnings

Xanax side effects | How long do side effects last? | Warnings | Interactions | How to avoid side effects

Xanax (alprazolam) is a popular prescription drug that is FDA-approved to treat generalized anxiety disorder (GAD) and panic disorder. It also may be prescribed off-label to treat short-term anxiety in children or premenstrual dysphoric disorder in women. 

Alprazolam, the active ingredient and generic name of Xanax, belongs to a class of drugs called benzodiazepines. These drugs slow down brain activity by amplifying the effects of a neurotransmitter called GABA, a chemical that blocks signals between nerves. 

As sedatives, both Xanax and Xanax XR (extended-release tablets) frequently cause side effects. Serious side effects are less common, but interactions with other drugs or existing medical conditions are possible. It is important for anyone taking Xanax to understand these potential problems and know how to manage them.

RELATED: What is Xanax? 

Xanax side effects

The most common side effects of Xanax are:

  • Sleepiness or fatigue
  • Dizziness or lightheadedness
  • Fainting
  • Memory problems
  • Slurred speech
  • Irritability
  • Confusion
  • Increased appetite or weight gain
  • Nausea
  • Constipation
  • Anxiety
  • Dry mouth or increased salivation
  • Decreased libido
  • Menstruation pain or irregularities
  • Low blood pressure
  • Impaired coordination and balance
  • Attention problems
  • Double vision
  • Liver problems
  • Loss of inhibitions

Serious side effects of Xanax

Serious side effects of Xanax include:

  • Dependency
  • Withdrawal
  • Substance abuse
  • Depression
  • Slowed breathing (respiratory depression)
  • Seizures
  • Suicidal thoughts and behaviors
  • Fast heartbeat (sinus tachycardia)
  • Severe allergic reactions such as angioedema and severe skin reactions

How long do side effects last?

The sedative side effects of Xanax—sleepiness, imbalance, coordination problems, and mental impairment—will go away as the drug is eliminated from the body. With a half-life of 11 hours, alprazolam is cleared from the body in about two days. However, alprazolam is metabolized into substances that work similarly to alprazolam, so it may take longer to fully recover mental sharpness.

Other common side effects on the nervous system, such as dry mouth, hypersalivation, fast heartbeat, and some of the paradoxical side effects (anxiety, irritation, agitation) will also go away within one to two days of taking the last dose.

Some side effects may require medical treatment such as fast heartbeat, respiratory depression, or severe allergic reactions. Some of these side effects, such as severe allergic reactions or withdrawal, may take days to weeks to resolve even with medical treatment. Xanax withdrawal typically lasts for 10–14 days, but in the most severe cases, Xanax withdrawal could persist for up to 12 months and could be fatal.

Xanax contraindications & warnings

There are risks when taking Xanax. Every person taking Xanax should be aware of potential pitfalls such as physical dependence, tolerance, substance abuse, withdrawal, and the possibility the drug will worsen existing medical conditions.

Abuse and dependence

Taking Xanax continuously can lead to physical dependence and tolerance. Taking prescription Xanax as directed also carries a risk of evolving into substance abuse. Benzodiazepines are commonly misused prescription drugs. About 1%–2% of people in the U.S. will at some point in their lives misuse benzodiazepines. Serious and even life-threatening overdoses and drug interactions are a common hazard when people abuse benzodiazepines. 

Abrupt discontinuation of Xanax can provoke withdrawal that can range from unpleasant to potentially life-threatening. Xanax withdrawal symptoms include:

  • Rebound anxiety
  • Panic attacks
  • Insomnia
  • Abnormal movements
  • Tremors
  • Blurred vision
  • Detachment from reality
  • Depression
  • Dizziness
  • Nausea
  • Vomiting
  • Diarrhea
  • Weight loss
  • High blood pressure
  • Fast heartbeat
  • Seizures
  • Delirium
  • Hallucinations
  • Psychosis
  • Suicidal thoughts and behaviors
  • Death

Withdrawal occurs suddenly when Xanax is abruptly discontinued and typically lasts for 10 to 14 days. Some people may experience protracted withdrawal (anxiety, impairment, insomnia, depression, creepy-crawly or prickling skin sensations, and weakness) that can last for up to 12 months. Long-term Xanax abuse or addiction may require specialized detox treatments to manage acute and protracted withdrawal.

Xanax must be discontinued in a gradually decreasing dose supervised by a healthcare provider to avoid withdrawal. Even with a tapered dose, some withdrawal symptoms may be experienced.


Depending on the dose, too much Xanax will cause drowsiness, dizziness, impairment, loss of coordination, diminished reflexes, coma, and possibly death. Serious adverse effects or death are more likely when large doses of Xanax are combined with alcohol or opioids. If too much Xanax has been taken, immediately call a poison helpline or go to an emergency room.


Though Xanax is widely prescribed, some people may not be able to take this drug safely. Others may require lower doses or additional monitoring to avoid potential problems.

  • People who are allergic to alprazolam should never be prescribed Xanax. 
  • Because alprazolam is habit-forming, Xanax treatment carries the risk of growing into substance abuse. For this reason, Xanax is used cautiously in those with a history of drug or alcohol abuse.
  • People with depression will be monitored for any worsening of the depression. Some people with depression may experience mania when taking Xanax.
  • People with liver problems will receive a lower dose of alprazolam because their bodies metabolize the drug slowly, raising the risk of side effects. In addition, those with kidney dysfunction or who are overweight will need to be checked regularly to avoid too much drug accumulating in the body and causing side effects.
  • Because Xanax slows down breathing, caution will be used in any person with lung disease or sleep apnea.  
  • Xanax can worsen certain medical conditions including myasthenia gravis, Parkinson’s disease, and porphyria. 
  • People with a history of seizures have a higher risk of seizures—including severe and life-threatening seizures (status epilepticus)—when Xanax is discontinued too quickly. 

Pregnancy and nursing

Pregnant women should avoid taking Xanax. Alprazolam crosses the placenta and can affect unborn babies. In the first trimester, alprazolam may cause birth defects and other fetal development problems. When taken in the last trimester, alprazolam can cause sedation, breathing problems, and withdrawal symptoms in a newborn baby.

Women who are breastfeeding should also avoid Xanax. Alprazolam is present in breast milk. A nursing infant can be affected by the drug and become sedated, sleepy, and have problems feeding. 


The Food and Drug Administration (FDA) has not approved the use of Xanax or generic alprazolam in children younger than 18 years. Although some doctors may prescribe a very short course of Xanax to treat anxiety in children, parents should be aware that children are more sensitive to the effects of Xanax than adults.


Older adults metabolize alprazolam more slowly than younger adults. For this reason, doctors will start with a lower dose to prevent side effects. In general, healthcare providers are advised to avoid giving drugs like Xanax to the elderly because of the risk of mental impairment, falls, injuries, and driving accidents.

Xanax interactions

Xanax can cause problems with a number of over-the-counter and prescription drugs. Many of these drug interactions are minor, but some can be very serious and even life-threatening.

  • CYP3A4 inhibitors delay the elimination of Xanax. Many of these are commonly prescribed drugs such as clarithromycin (an antibiotic), ketoconazole (an antifungal), itraconazole (another antifungal), common HIV drugs, DHEA supplements, and grapefruit.  
  • Opioids. Xanax and other benzodiazepines come with a black-box warning to avoid combining opioid pain relievers with Xanax. The combination could cause sedation, slowed breathing, respiratory depression, and death. 
  • Central nervous system depressants. Because of the risk of sedation and respiratory depression, other drugs to avoid include other benzodiazepines, barbiturates, and sedatives. Xanax should be avoided or used with caution with other depressants such as antihistamines, antipsychotics, anxiety drugs, tricyclic antidepressants, monoamine oxidase inhibitors, and anticonvulsants. Some common over-the-counter supplements are also CNS depressants and should be avoided when taking benzodiazepines. These include licorice, melatonin, and kava.

How to avoid Xanax side effects

Many people taking Xanax will experience side effects. A few tips can help either avoid or manage side effects caused by Xanax.

1. Take Xanax as directed

Take the dose exactly as prescribed, usually 0.25–3 mg taken three times a day. A doctor or other healthcare provider may provide a dosing schedule. Don’t take extra medicine or skip a dose. 

2. Tell the doctor about all medical conditions

To avoid side effects, the doctor or other healthcare professional prescribing Xanax needs to be aware of all current and past mental health and medical conditions, especially:

  • Depression or mood problems
  • Suicidal thoughts or behaviors
  • Liver or kidney problems
  • Lung or breathing problems
  • Any history of seizures
  • Pregnancy or pregnancy plans
  • Breastfeeding or any plans to breastfeed
  • Any history of drug or alcohol abuse

3. Tell the doctor about all medications being taken

Some Xanax side effects are worsened by drug interactions. Many prescription drugs and supplements can dramatically worsen the side effects of alprazolam by blocking the liver’s ability to metabolize it. Before starting Xanax, make sure the doctor, healthcare provider, or pharmacist knows about Xanax before filling the prescription. Tell your healthcare provider about all prescriptions, over-the-counter drugs, and supplements that are taken regularly, particularly:

  • Opioids
  • Anxiety drugs
  • Sedatives or sleep aids
  • Any other drug that causes drowsiness or sleepiness

4. Be careful about driving and other risky activities

Most people taking Xanax will experience some form of mental impairment: drowsiness, bad coordination, balance problems, and trouble focusing. As a result, injuries, falls, and traffic accidents are commonly associated with prescription benzodiazepines. Driving, operating machinery, or engaging in any potentially hazardous activity that requires full attention and focus should be avoided when first taking Xanax. When the effects of Xanax on mental impairment are no longer experienced after a week or two, it may be possible to resume driving or other activities cautiously.

5. Remove hazards from the house

Falls and injuries due to mental impairment are possible when taking Xanax. Older adults are particularly vulnerable. Before starting Xanax, try to remove obstacles and tripping hazards around the house such as coffee tables. Some daily activities, such as using knives, may need to be curtailed if mental impairment is too pronounced.

6. Don’t drink alcohol

Do not drink alcohol while taking Xanax. The combination increases sedation, balance problems, and the risk for injury. The combination can also increase the risk of breathing problems. It’s a good idea to also avoid prescription or nonprescription drugs that cause sleepiness, like antihistamines. In particular, don’t combine Xanax with other benzodiazepines such as Ativan (lorazepam), Valium (diazepam), or Klonopin (clonazepam).  

7. Watch for signs of breathing problems

Some people will notice that Xanax slows down their breathing. This could be a serious problem in any person with lung problems or who is drinking alcohol or taking other depressants. When taking Xanax, watch for signs that breathing has become too slow and shallow to adequately supply the body with oxygen. These signs include blue lips, blue skin, shallow breathing, difficulty breathing, or changes in heart rate. Emergency medical attention is required in that situation.

8. Do not stop taking Xanax

Xanax can cause withdrawal when stopped suddenly. In some cases, the withdrawal can be severe and even life-threatening. In cases where the drug does not seem to be working or the side effects make it too difficult to take, get medical advice from a doctor or other healthcare professional before stopping the medicine. Whether or not there are other treatment options, a progressively tapered dose will be used to avoid withdrawal while stopping the medication.

Related resources for Xanax side effects:

  • A review of alprazolam use, misuse, and withdrawal, Journal of Addiction Medicine 
  • Absence of food effect on the extent of alprazolam absorption from an orally disintegrating tablet, Pharmacotherapy
  • Alprazolam compound summary, U.S. National Library of Medicine
  • Alprazolam drug summary, Prescriber’s Digital Reference
  • Benzodiazepine toxicity, StatPearls
  • How long does it take to detox from Xanax?, Oxford Treatment center
  • Xanax, Epocrates
  • Xanax prescribing information, U.S. National Library of Medicine
  • Xanax XR prescribing information, U.S. National Library of Medicine

Side Effects Of Xanax (Alprazolam) From Long-Term Use And Abuse

Xanax is the brand name of alprazolam, a benzodiazepine drug prescribed to treat anxiety and panic disorders. This sedative-hypnotic substance targets the brain chemical responsible for relaxation and enhances its effects. Xanax depresses the central nervous system to reduce restlessness, decrease brain activity and slow breathing.

As a result, people with high anxiety feel calmer after taking Xanax. Even those without an anxiety disorder may enjoy the pleasant feeling that Xanax produces. Xanax is a fast-acting drug that provides quick relief, which leads many individuals to abuse it.

Some people may use Xanax for years in order to combat anxiety, whether or not their doctor has approved it. An individual may continue to take Xanax as prescribed, or they may take more, hoping it will have a greater effect. People without a prescription may obtain Xanax from someone who does or purchase it online.

As with any prescription drug, Xanax comes with a risk of adverse side effects that is increased with excessive use and abuse. Side effects of prolonged Xanax use may include:

  • dry mouth
  • blurred vision
  • nausea or vomiting
  • constipation
  • weight and appetite changes
  • dizziness
  • drowsiness or sedation
  • difficulty concentrating
  • irritability or depression
  • skin rash, yellow skin or eyes
  • trouble breathing

More serious side effects that can occur with long-term Xanax use affect the way a person thinks and acts. Some individuals may experience:

  • visual or auditory hallucinations
  • mania (increased energy and talkativeness)
  • violent or aggressive behavior
  • suicidal thoughts and actions

Perhaps the most deadly side effects of long-term Xanax use and abuse are seizures. This is an intense brain disturbance that may cause the body to spasm. Seizures can result in brain damage or death if they occur repeatedly or for last a long period of time. They are not only a risk of Xanax use, but can also be caused by Xanax withdrawal.


Xanax Dependence And Withdrawal

Even with recommended use, the body develops a tolerance to Xanax (alprazolam). This means that, over time, the effects of the drug become less intense. An individual must take more Xanax to have the same effect.

This is often the first step toward physical dependence, a condition in which the body needs Xanax to function normally. If someone is physically dependent on Xanax, they will experience withdrawal symptoms such as muscle cramps, vomiting, sweating, tremors, convulsions or seizures. Withdrawal from Xanax can be life-threatening.

Xanax has a short half-life, which means that its effects do not last long. The time period between doses of Xanax may cause someone to experience mild withdrawal symptoms. This leads some people to take Xanax more frequently than prescribed in an effort to avoid unpleasant effects. Unfortunately, this is how many people become addicted to Xanax.

Though Xanax is the most popular anti-anxiety medication in the United States, many doctors are hesitant to prescribe it, especially for long periods of time. Some may initially approve Xanax use in individuals with panic attacks then switch them to a drug with a longer-lasting effect for anxiety, hoping to lessen the risk of dependence and addiction.

Xanax Overdose

If a person takes too much Xanax in a small time frame, they could experience an overdose that results in drowsiness, confusion, impaired coordination, slow reflexes, coma or death.

This does not only result from taking too much Xanax at once. Since benzodiazepines like Xanax are stored in body fat, they can remain in someone’s system for a long time. With repeated Xanax use, the drug can build up in the body and increase the risk of overdose.

Taking Xanax with other central nervous system depressants presents a high overdose risk. Opioids and alcohol produce some of the same effects as Xanax, and when these effects are compounded, they may be fatal. Mixing central nervous system depressants can result in extreme drowsiness, respiratory depression (trouble breathing), coma or death.

Though less common and less effective, some people take Xanax by snorting (insufflating) or injecting it. These methods can also raise the likelihood of overdose, as the drug gets into the bloodstream quicker and it is more difficult to predict its effects.

Effects Of Xanax On The Body And Brain

Since Xanax is a central nervous system depressant, it generally reduces heart rate. However, some people have experienced tachycardia (rapid heart rate) and palpitations (fluttering in the heart) when taking Xanax. These cardiovascular effects may also occur when someone stops taking Xanax, as the body’s reaction to increased anxiety levels.

Some people experience elevated liver enzymes when using Xanax long-term. This may be a sign of liver inflammation, a condition that can lead to or result from damage to liver tissue. Liver damage is even more likely if Xanax is combined with alcohol.

Long-term Xanax use and abuse may also cause cognitive impairment, especially regarding long-term memory. A study in the British Medical Journal found that prolonged Xanax use increases a person’s risk of developing Alzheimer’s disease, a progressive mental disorder indicated by poor memory and thinking skills.

Dangers Of Xanax Addiction

Xanax works by increasing the activity of gamma-aminobutyric acid (GABA) in the brain. The more that Xanax is used, the less the brain regulates this chemical on its own. This causes fluctuating rates of GABA, which is why seizures may occur from either abusing Xanax or abruptly stopping Xanax use.

When a person stops taking Xanax, the brain has to readjust to producing GABA naturally. This can mean a period of time in which brain activity is increased and anxiety is higher because the brain is no longer as efficient at self-regulating. This is what leads people to develop a Xanax addiction.

While physical dependence is the body’s reaction to prolonged Xanax use, an addiction develops in the mind. Changes in brain function can cause a person to crave Xanax and continue taking it even when it no longer makes them feel good.

Addiction is a chronic mental disease that can take over a person’s life. When someone loses control over their drug use, Xanax becomes the most important thing in their life. Their priorities are realigned, and the result is often detrimental to their relationships, productivity, and health.


Find Treatment For Xanax Addiction

Our comprehensive treatment programs for Alprazolam addiction begin with medically assisted detoxification. Medical professionals monitor each individual through the withdrawal process, watching their vital signs and administering medication if needed. Once Xanax is cleared from a person’s system, they can begin treatment for addiction.

The compassionate staff at Vertava Health works with every person to create a unique treatment plan for their needs. There is no one-size-fits-all solution to addiction. A combination of evidence-based treatment methods is the most effective way to ensure a full recovery.

Behavioral therapy, individual and group counseling, recreation, nutrition, and art therapy are used in many of our addiction treatment programs. We believe that focusing only on the addiction is not enough. True healing involves the whole person—mind, body, and spirit.

To learn more about Xanax addiction treatment, speak with one of our specialists today.

Benadryl and Xanax: A Deadly Combination

As a faith-based drug and alcohol treatment center, we know that a lot of people either experiment with combining medications or don’t realize the harm it can do.

While people may be aware of the dangers of binge drinking or abusing drugs like cocaine or heroin, not everyone thinks twice about the effects of mixing over-the-counter and prescription medications like Benadryl and Xanax. Mixing Xanax and Benadryl can be particularly harmful; this combination is known for causing adverse side effects and even overdose.

What Is Benadryl?

Benadryl is the generic brand name for diphenhydramine, which is an antihistamine used to treat allergies, hay fever, and cold symptoms. Benadryl can treat symptoms like rashes, itching, runny nose and cough. It’s also used for colds because it can help you fall asleep and stay asleep. Benadryl works by blocking histamines, which are chemicals that your immune system releases in an attempt to rid itself of an allergy. As an antihistamine, Benadryl is specifically designed to alleviate symptoms caused by these chemicals.

Although this over-the-counter medicine can help alleviate uncomfortable symptoms, it can be dangerous in high doses. Some possible side effects of Benadryl include:

  • Dry mouth
  • Dizziness
  • Constipation
  • Stomach pains
  • Blurred vision
  • Dry throat
  • Confusion
  • Irregular heartbeat

Because of its main ingredient, diphenhydramine, Benadryl is addictive. As an over-the-counter medicine, many people have access to it in tablets, capsules, and liquid form. People who develop an addiction to it may need professional help to quit. A medically monitored detox like the one we offer at Faith in Recovery can help people wean off of Benadryl and begin recovering.

What Is Xanax?

Xanax, or alprazolam, is a prescription medication used to treat anxiety, panic disorders, and insomnia. It belongs to a class of drugs called benzodiazepines, which work by targeting nerve activity in the central nervous system to produce calming effects. Xanax works by enhancing an inhibitory transmitter in the brain called gamma-aminobutyric acid (GABA), which blocks certain brain signals and reduces nerve activity in the brain. Individuals who suffer from overactive nerves, like those with anxiety disorders, can benefit from Xanax. 

Like many other benzos and prescription drugs, however, Xanax is addictive and can cause serious side effects when abused. 

Some adverse side effects of Xanax include: 

  • Dizziness
  • Hallucinations
  • Slurred speech
  • Loss of coordination
  • Issues with memory
  • Trouble breathing

Although these symptoms usually occur when Xanax is taken in extreme doses, people who develop a tolerance to it will take a higher dosage more often in order to experience the same effects. This can quickly turn into dependency. Prescription pill addiction treatment is often the most effective form of help for people with a Xanax addiction.

Can You Take Benadryl And Xanax at the Same Time?

No, you should not take Benadryl and Xanax together. Taking Xanax and Benadryl together can intensify side effects like dizziness, fatigue, drowsiness, inability to concentrate, and lack of coordination. Combining Benadryl and Xanax can be especially dangerous for the elderly. Like many drug reactions, the effects of either medication can be intensified or their combined side effects could cause a horrible chain of physical reactions. The number one reason you should not take Xanax and Benadryl together is that they’re both addictive. A person who becomes accustomed to frequently taking both together may require residential addiction treatment to quit.

As a Christian rehab center, we know the dangers of mixing Benadryl and Xanax and how they can disrupt a person’s life.

If you or someone you know has developed an addiction call us today at 888-280-4763 to find out more about our faith-based levels of care..

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Alprazolam tablets

What is this medicine?

ALPRAZOLAM (al PRAY zoe lam) is a benzodiazepine. It is used to treat anxiety and panic attacks.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.


What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • an alcohol or drug abuse problem
  • bipolar disorder, depression, psychosis or other mental health conditions
  • glaucoma
  • kidney or liver disease
  • lung or breathing disease
  • myasthenia gravis
  • Parkinson’s disease
  • porphyria
  • seizures or a history of seizures
  • suicidal thoughts
  • an unusual or allergic reaction to alprazolam, other benzodiazepines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor’s advice.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • certain antiviral medicines for HIV or AIDS like delavirdine, indinavir
  • certain medicines for fungal infections like ketoconazole and itraconazole
  • narcotic medicines for cough
  • sodium oxybate

This medicine may also interact with the following medications:

  • alcohol
  • antihistamines for allergy, cough and cold
  • certain antibiotics like clarithromycin, erythromycin, isoniazid, rifampin, rifapentine, rifabutin, and troleandomycin
  • certain medicines for blood pressure, heart disease, irregular heart beat
  • certain medicines for depression, like amitriptyline, fluoxetine, sertraline
  • certain medicines for seizures like carbamazepine, oxcarbazepine, phenobarbital, phenytoin, primidone
  • cimetidine
  • cyclosporine
  • female hormones, like estrogens or progestins and birth control pills, patches, rings, or injections
  • general anesthetics like halothane, isoflurane, methoxyflurane, propofol
  • grapefruit juice
  • local anesthetics like lidocaine, pramoxine, tetracaine
  • medicines that relax muscles for surgery
  • narcotic medicines for pain
  • other antiviral medicines for HIV or AIDS
  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Tell your doctor or health care professional if your symptoms do not start to get better or if they get worse.

Do not stop taking except on your doctor’s advice. You may develop a severe reaction. Your doctor will tell you how much medicine to take.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. To reduce the risk of dizzy and fainting spells, do not stand or sit up quickly, especially if you are an older patient. Alcohol may increase dizziness and drowsiness. Avoid alcoholic drinks.

If you are taking another medicine that also causes drowsiness, you may have more side effects. Give your health care provider a list of all medicines you use. Your doctor will tell you how much medicine to take. Do not take more medicine than directed. Call emergency for help if you have problems breathing or unusual sleepiness.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breathing problems
  • confusion
  • loss of balance or coordination
  • signs and symptoms of low blood pressure like dizziness; feeling faint or lightheaded, falls; unusually weak or tired
  • suicidal thoughts or other mood changes

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • dizziness
  • dry mouth
  • nausea, vomiting
  • tiredness

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children. This medicine can be abused. Keep your medicine in a safe place to protect it from theft. Do not share this medicine with anyone. Selling or giving away this medicine is dangerous and against the law.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). This medicine may cause accidental overdose and death if taken by other adults, children, or pets. Mix any unused medicine with a substance like cat litter or coffee grounds. Then throw the medicine away in a sealed container like a sealed bag or a coffee can with a lid. Do not use the medicine after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

alprazolam Uses, Side Effects, Dosage & Interactions


oval, orange, imprinted with XANAX 0.5


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Xanax (Alprazolam) Side Effects, Symptoms & Signs of Abuse

Article at a Glance:

  • Xanax is the brand name of alprazolam, a benzodiazepine drug. Alprazolam has many common side effects.
  • As a Schedule IV controlled substance, Xanax can lead to abuse, dependence and addiction.
  • Signs of Xanax addiction can be physical, psychological or behavioral in nature.
  • Taking too much Xanax can cause an overdose, which may be deadly.

An Overview

Xanax, the brand name of the generic drug alprazolam, is a prescription benzodiazepine that treats anxiety and panic. As of 2018, Xanax is one of the most prescribed medications in the United States. The drug is also a Schedule IV controlled substance, meaning it carries a risk of addiction.

Like all drugs, Xanax has some side effects. People who abuse Xanax or are addicted to it may attempt to hide these side effects. However, there are a variety of signs and symptoms that indicate Xanax abuse and addiction.

Minor Xanax Side Effects

Xanax is FDA-approved to treat anxiety. As a benzodiazepine, it reduces the activity level in the brain, making neurons in the brain less excitable. This can result in a temporary reduction of physical tension, anxiety and restlessness. However, Xanax can also bring various adverse reactions.

Common side effects of Xanax include:

  • Decreased or increased appetite
  • Weight loss or gain
  • Watering of the mouth
  • Increased or decreased interest in sexual intercourse
  • Difficulty with bowel movements
  • Cracked or dry skin
  • Abdominal cramping
  • Double vision

If you have any questions or concerns about Xanax side effects, contact your doctor to determine if you should seek treatment.

Major Xanax Side Effects

There can be major Xanax side effects as well, even when the drug is taken as prescribed. Notify your doctor immediately if you experience any of the following effects, as many of these signs would warrant medical attention:

  • Lightheadedness
  • Clumsiness or unsteadiness
  • Shakiness
  • Irritability
  • Trouble speaking or sleeping
  • Difficulty concentrating
  • Forgetfulness
  • Mental status changes
  • Diarrhea

Signs of Xanax Abuse

Many people with a Xanax addiction started with a legitimate and legal prescription. However, a person may increase their Xanax dose beyond the recommendations of a doctor and find themselves misusing the drug. Misuse can quickly lead to dependence and addiction.

There are many possible side effects that can result from Xanax abuse. These signs and symptoms can indicate to friends and family that their loved one has a harmful Xanax addiction. While some of these signs are observable physical symptoms, others are psychological or behavioral changes.

Physical Side Effects of Xanax Abuse

Xanax can have observable physical effects on the body, including sleepiness and relaxed mood. In an overdose, however, physical signs can be even more obvious and include:

  • Extreme drowsiness
  • Coordination problems
  • Decreased reflexes
  • Slowed breathing

A Xanax overdose can be deadly. If you suspect an overdose, seek emergency medical attention.

Psychological Symptoms of Abuse

People abusing Xanax or other benzodiazepines can show different psychological symptoms. Many of these symptoms are changes in mood, such as:

  • Amnesia
  • Hostility
  • Irritability
  • Vivid or disturbing dreams

Behavioral Signs of Abuse

Often, a person struggling with a substance like Xanax will show changes in behavior. Loved ones may notice these signs, which can appear either slowly or suddenly. Some of these signs include:

  • Regularly skipping school or work: Keep an eye out for a sudden loss of interest in daily activities or a sudden drop in grades or performance, school or work involvement.
  • Secretive behavior: If a friend or family member goes to great lengths to keep people out of their room, they may be hiding something. The person may shut doors when someone enters the house or close and lock the bathroom door, even when not using the restroom.
  • Relationship changes: A person may shift friend groups as they seek the companionship of others who also abuse substances.
  • Doctor shopping: A person may visit several physicians to obtain more Xanax prescriptions.
  • Antisocial behaviors: By pushing away friends and loved ones, a person may be trying to avoid the detection of their addiction. If a formerly outgoing person has suddenly begun keeping to themselves, it may be a sign of drug abuse.
  • Paraphernalia: People with a moderate-to-severe Xanax addiction may crush and snort the medication to speed up its effects. Paraphernalia may include a mortar and pestle, razor blades and credit cards, rolled-up dollar bills and straws. Multiple empty pill bottles should also raise a red flag.
  • Financial problems: A person with a Xanax addiction usually searches out more of the drug, leading to changes in their financial situation. Frequent and sudden requests for money are often a sign of secretive spending, which may indicate non-prescription Xanax use. They may also borrow funds from friends and family without paying them back.
  • Legal trouble: If a person’s struggle with Xanax has reached the point where they are having run-ins with the law and require legal representation, drug abuse has become a problem. Many people do not realize that redistributing or reselling prescription medication from one individual to another is illegal. It carries similar consequences to dealing illicit drugs like heroin or cocaine.

Effects of Long-Term Xanax Abuse

When someone uses a benzodiazepine like Xanax for extended periods of time, there is a risk of long-term side effects. These can include:

  • Cognitive impairment: Multiple studies have found that long-term use of benzodiazepines is linked to developing dementia. However, some studies cast doubt on this relationship.
  • Motor vehicle crashes: Driving while taking a benzodiazepine carries risks that are similar to driving with a blood alcohol level between 0.050% and 0.079%.
  • Hip fracture: In older adults, taking a benzodiazepine can increase the risk of hip fracture by at least 50%.
  • Chemical dependency or addiction: As a controlled substance, Xanax carries the risk of abuse, dependence and addiction.

For these reasons, it’s best to take Xanax only as prescribed and only for the length of time that it’s prescribed.

Xanax Withdrawal Symptoms

When addiction is a factor, the risk of withdrawal becomes a factor as well. People with a Xanax addiction increase their chances of withdrawal if they stop taking the medication. Xanax withdrawal symptoms include:

  • Anxiety
  • Trouble sleeping
  • Restlessness
  • Agitation
  • Irritability
  • Problems with concentration and memory
  • Muscle tension or aches
  • Seizures may occur in severe cases

These symptoms begin one to two days after the last dose of Xanax and can last for two to four weeks. To avoid these symptoms, a medically supervised taper may be necessary. Medical detox in a rehab facility like The Recovery Village can help a person safely taper their dose while receiving treatment for withdrawal symptoms.

Can You Overdose on Xanax?

It is possible to fatally overdose on Xanax. In fact, Xanax is one of the top 10 drugs implicated in overdose deaths in the United States. Further, mixing Xanax with other central nervous system depressants, such as opioids, also carries an overdose risk. Benzodiazepines like Xanax are involved in 33% of prescription opioid overdose deaths.

Learning to recognize the symptoms of a benzodiazepine overdose may help you save a person’s life.

Some signs of Xanax overdose include:

  • Excessive sedation
  • Impaired mental status
  • Drowsiness
  • Slurred speech
  • Movement problems
  • Slowed breathing

Drug overdose can be fatal. If you suspect someone is experiencing an overdose, call 911 immediately. Do NOT be afraid to seek help. If you do not have access to a phone contact Web Poison Control Services for online assistance.

Xanax overdose can be difficult to spot because symptoms are similar to those of alcohol and opioids, which are commonly abused in combination with Xanax. Since these symptoms overlap with overdose symptoms of other depressants, however, you should learn to recognize them and call for medical help when necessary.

DSM-V Criteria for Xanax Addiction Severity (Mild, Moderate, Severe)

Although the DSM-5 does not specifically recognize Xanax addiction, it does recognize substance use disorders involving benzodiazepines. A substance use disorder can be mild, moderate or severe and is staged based on symptoms like:

  • Cravings
  • Needing higher doses of the drug to get the same effect
  • Loss of control
  • Losing interest in favorite activities
  • Avoiding responsibilities
  • Withdrawal symptoms when the drug is stopped

Preventing Addiction

The best way to prevent a Xanax addiction is to only use the drug when it is prescribed to you and take it exactly as prescribed. Strategies to help you prevent addiction and use Xanax responsibly include:

  • Take only the dose than your doctor prescribes; do not take a higher dose than your doctor tells you to take.
  • Take Xanax only as often as prescribed; do not take the drug more frequently than it is prescribed to be taken.
  • Take only what is prescribed to you; in addition to being illegal, borrowing or buying Xanax puts you at a higher risk of addiction.

Find the Help You Need

If you or someone you love struggles with Xanax, help is available at The Recovery Village. Our multidisciplinary team of experts can create an individualized treatment program that helps you recover from Xanax abuse and addiction. Contact us today to learn more about recovery plans and programs that can work well for your needs.

  • Sources

    ClinCalc. “Alprazolam.” Accessed January 17, 2021.

    Drug Enforcement Agency. “Controlled Substances.” December 21, 2020. Accessed January 17, 2021.

    Drugs.com. “Alprazolam.” November 4, 2020. Accessed January 17, 2021.

    Drug Enforcement Administration. “Benzodiazepines.” April 2020. Accessed January 17, 2021.

    Zhong, GuoChao; Wang, Yi; Zhang, Yong; Zhao, Yong. “Association between Benzodiazepine Use and Dementia: A Meta-Analysis.” PLoS One, May 27, 2015. Accessed January 17, 2021.

    Nader, Danilo; Gowing, Linda. “Is Long-Term Benzodiazepine Use a Risk Factor for Cognitive Decline? Results of a Systematic Review.” Journal of Addiction, January 24, 2020. Accessed January 17, 2021.

    Johnson, Brian; Streltzer, Jon. “Risks Associated with Long-Term Benzodiazepine Use.” American Family Physician, August 15, 2013. Accessed January 17, 2021.

    World Health Organization. “Clinical Guidelines for Withdrawal Management and Treatment of Drug Dependence in Closed Settings.” 2009. Accessed January 17, 2021.

    Hedegaard, Holly; Bastian, Brigham A.; Trinidad, James P.; et al. “Regional Differences in the Drugs Most Frequently Involved in Drug Overdose Deaths: United States, 2017.”  National Vital Statistics Reports, October 25, 2019. Accessed January 17, 2021.

    Gladden, R. Matt; O’Donnell, Julie; Mattson, Christine L.; Seth, Puja. “Changes in Opioid-Involved Overdose Deaths by Opioid Type and Presence of Benzodiazepines, Cocaine, and Methamphetamine — 25 States, July–December 2017 to January–June 2018.” Centers for Disease Control and Prevention, August 30, 2019. Accessed January 17, 2021.

    BMJ Best Practice. “Benzodiazepine overdose.” December 18, 2020. Accessed January 17, 2021.

    VisualDX. “Benzodiazepine use disorder.” March 28, 2019. Accessed January 17, 2021.

    National Institute on Drug Abuse. “What Are Signs of Drug Use in Adolescents, and What Role Can Parents Play in Getting Treatment?” January 2014. Accessed January 17, 2021.

Medical Disclaimer: The Recovery Village aims to improve the quality of life for people struggling with a substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare provider.

Xanax instructions for use: indications, contraindications, side effects – description of Xanax tab. 500 mcg: 30 pcs. (1427)

💊 Composition of the preparation Xanax ®

✅ Application of Xanax ®


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⚠️ The state registration of this drug has been canceled

Description of the active components of the drug

Xanax ®
(Xanax ® )

The scientific information provided is generalized and cannot be used to make
decisions about the possibility of using a particular drug.

Update date: 2020.11.07

Marketing authorization holder:

Dosage form

Xanax ®

Tab.500 mcg: 30 pcs.

reg. No .: P N013211 / 01-2001
from 20.07.01
– Cancellation of State. registration

Release form, packaging and composition
preparation Xanax


Tablets 1 tab.
alprazolam 500 μg

10 pcs. – contour cell packaging (3) – cardboard packs.

Pharmacological action

Anxiolytic agent (tranquilizer), a triazolo-benzodiazepine derivative. It has anxiolytic, sedative, hypnotic, anticonvulsant, central muscle relaxant effect.The mechanism of action is to enhance the inhibitory effect of endogenous GABA in the central nervous system by increasing the sensitivity of GABA receptors to the mediator as a result of stimulation of benzodiazepine receptors located in the allosteric center of postsynaptic GABA receptors of the ascending activating reticular formation of the brainstem and interneurons of the lateral horns of the spinal cord; reduces the excitability of the subcortical structures of the brain (limbic system, thalamus, hypothalamus), inhibits polysynaptic spinal reflexes.

Pronounced anxiolytic activity (decrease in emotional stress, weakening of anxiety, fear, anxiety) is combined with a moderately pronounced hypnotic effect; shortens the period of falling asleep, increases the duration of sleep, reduces the number of night awakenings. The mechanism of hypnotic action is to inhibit the cells of the reticular formation of the brain stem. Reduces the impact of emotional, autonomic and motor stimuli that disrupt the mechanism of falling asleep.


After oral administration, alprazolam is rapidly and completely absorbed from the gastrointestinal tract. C max in blood plasma is achieved within 1-2 hours.

Plasma protein binding is 80%.

Metabolized in the liver.

T 1/2 averages 12-15 hours. Alprazolam and its metabolites are excreted mainly by the kidneys.

Indications of the active substances of the drug



Anxiety, neuroses, accompanied by a feeling of anxiety, danger, anxiety, tension, sleep impairment, irritability, as well as somatic disorders; mixed anxiety-depressive states; neurotic reactive-depressive states, accompanied by a decrease in mood, loss of interest in the environment, anxiety, loss of sleep, loss of appetite, somatic disorders; anxiety and neurotic depression, developed against the background of somatic diseases; panic disorder with and without phobic symptoms.

Dosing regimen

Method of application and dosage regimen of a particular drug depends on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a particular drug with the indications for use and the dosage regimen.

Individual.The minimum effective dose is recommended. The dose is adjusted in the course of treatment, depending on the achieved effect and tolerance. If it is necessary to increase the dose, it should be increased gradually, first in the evening, and then in the afternoon.

The initial dose is 250-500 mcg 3 times / day, if necessary, a gradual increase to 4.5 mg / day is possible.

For elderly or debilitated patients, the initial dose is 250 mcg 2-3 times / day, maintenance doses are 500-750 mcg / day, if necessary, taking into account the tolerance, the dose can be increased.

Cancellation or reduction of the dose of alprazolam should be carried out gradually, reducing the daily dose by no more than 500 mcg every 3 days; sometimes an even slower cancellation may be required.

Side effects

From the side of the central nervous system: at the beginning of treatment (especially in elderly patients) drowsiness, fatigue, dizziness, decreased ability to concentrate, ataxia, disorientation, unsteadiness of gait, slowing of mental and motor reactions; rarely – headache, euphoria, depression, tremor, memory loss, impaired coordination of movements, depression of mood, confusion, dystonic extrapyramidal reactions (uncontrolled movements, incl.h. eyes), weakness, myasthenia gravis, dysarthria; in some cases – paradoxical reactions (aggressive outbursts, confusion, psychomotor agitation, fear, suicidal tendencies, muscle spasm, hallucinations, agitation, irritability, anxiety, insomnia).

From the digestive system: possible dry mouth or salivation, heartburn, nausea, vomiting, loss of appetite, constipation or diarrhea, liver dysfunction, increased activity of hepatic transaminases and alkaline phosphatase, jaundice.

From the hematopoietic system: possible leukopenia, neutropenia, agranulocytosis (chills, hyperthermia, sore throat, excessive fatigue or weakness), anemia, thrombocytopenia.

From the urinary system: possible urinary incontinence, urinary retention, impaired renal function, decreased or increased libido, dysmenorrhea.

From the endocrine system: possible changes in body weight, libido disturbances, menstrual irregularities.

From the side of the cardiovascular system: a decrease in blood pressure, tachycardia is possible.

Allergic reactions: possible skin rash, itching.

Contraindications to use

Coma, shock, myasthenia gravis, angle-closure glaucoma (acute attack or predisposition), acute alcohol poisoning (with weakening of vital functions), opioid analgesics, hypnotics and psychotropic drugs, chronic obstructive respiratory diseases with initial manifestations of respiratory failure, acute respiratory failure, severe depression (suicidal tendencies may occur), pregnancy (especially the first trimester), lactation, children and adolescence up to 18 years, hypersensitivity to benzodiazepines.

Use during pregnancy and lactation

Alprazolam has a toxic effect on the fetus and increases the risk of developing congenital defects when used in the first trimester of pregnancy. Continuous use during pregnancy can lead to physical dependence with the development of withdrawal syndrome in the newborn. Reception in therapeutic doses in later stages of pregnancy can cause depression of the central nervous system of the newborn.Application immediately before childbirth or during childbirth can cause respiratory depression, decreased muscle tone, hypotension, hypothermia and weak sucking in the newborn (sluggish sucking syndrome of the newborn).

It is possible that benzodiazepines are excreted in breast milk, which can make the newborn sleepy and make feeding difficult.

In experimental studies showed that alprazolam and its metabolites are excreted in breast milk.

Application for violations of liver function

Alprazolam should be used with caution in patients with impaired liver function.

Application for impaired renal function

Alprazolam should be used with caution in patients with impaired renal function.

Use in children

Contraindication: children and adolescents under 18 years of age.

Use in elderly patients

For elderly or debilitated patients, the initial dose is 250 mcg 2-3 times / day, maintenance doses are 500-750 mcg / day, if necessary, taking into account the tolerance, the dose can be increased.

Special instructions

For endogenous depression, alprazolam can be used in combination with antidepressants. With the use of alprazolam in patients with depression, cases of the development of hypomanic and manic states have been noted.

Alprazolam should be used with caution in patients with impaired liver and / or kidney function.

In patients who have not previously taken drugs that affect the central nervous system, alprazolam is effective in lower doses, compared with patients who received antidepressants, anxiolytics, or suffering from chronic alcoholism.

With prolonged use in high doses, addiction and drug dependence may develop, especially in patients prone to drug abuse.

With a rapid dose reduction or abrupt withdrawal of alprazolam, a withdrawal syndrome is observed, the symptoms of which can range from mild dysphoria and insomnia to a severe syndrome with abdominal and skeletal muscle cramps, vomiting, increased sweating, tremors and seizures. Withdrawal syndrome is more common in individuals for a long time (more than 8-12 weeks.) who received alprazolam.

Do not use other tranquilizers simultaneously with alprazolam.

The safety of using alprazolam in children and adolescents under the age of 18 has not been established. Children, especially at a younger age, are very sensitive to the inhibitory effect of benzodiazepines on the central nervous system.

Avoid drinking alcohol during treatment.

Influence on the ability to drive vehicles and mechanisms

During the period of treatment, one should refrain from engaging in potentially hazardous activities that require increased attention and speed of psychomotor reactions (driving vehicles or working with mechanisms).

Drug interactions

With the simultaneous use of psychotropic, anticonvulsant, drugs and ethanol, an increase in the inhibitory effect of alprazolam on the central nervous system is observed.

With the simultaneous use of blockers of histamine H 2 -receptors reduce the clearance of alprazolam and increase the inhibitory effect of alprazolam on the central nervous system; antibiotics from the macrolide group – reduce the clearance of alprazolam.

With the simultaneous use of hormonal contraceptives for oral administration increase T 1/2 alprazolam.

With the simultaneous use of alprazolam with dextropropoxyphene, a more pronounced depression of the central nervous system is observed than in combination with other benzodiazepines, because an increase in the concentration of alprazolam in blood plasma is possible.

Simultaneous intake of digoxin increases the risk of developing intoxication with cardiac glycosides.

Alprazolam increases the concentration of imipramine in the blood plasma.

With the simultaneous use of itraconazole, ketoconazole enhance the effects of alprazolam.

With the simultaneous use of paroxetine, it is possible to enhance the effects of alprazolam, due to the inhibition of its metabolism.

Fluvoxamine increases the plasma concentration of alprazolam and the risk of developing its side effects.

With the simultaneous use of fluoxetine, it is possible to increase the concentration of alprazolam in the blood plasma due to a decrease in its metabolism and clearance under the influence of fluoxetine, which is accompanied by psychomotor disorders.

The possibility of enhancing the action of alprazolam while being used with erythromycin cannot be ruled out.


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Ate and Died Pills Give Americans Happiness.And then they turn into zombies: Society: World: Lenta.ru

Stories about the epidemic of opioid drugs in the United States have long become commonplace: in the country every day more than a hundred people die from an overdose of heroin, fentanyl and similar substances. A health emergency has already been declared to combat them, but another attack rarely makes it to the front pages of local media. We are talking about the mass enthusiasm for the drug “Xanax” (Xanax, in English pronunciation – “Zanax”). Today, millions of Americans are forced to live in a frantic pace, and for many of them it is the Xanax pill that helps to gather strength, calm down and feel like a human being.”Lenta.ru” figured out how the daily “duty” pill for anxiety drives its victims into the graves.

“He rips me out of the dark bubble of anxiety and lifts me up to the cloud! From there, I can look at everything from top to bottom and not sweat it. I am calm and collected. It also helps me sleep, and I am grateful to him, “- this is how the effect of taking Xanax is described by a Reddit user under the nickname wizardswrath00.

“Anxiety is a real bitch. Euphoria comes when you understand: you are no longer in her power. Xanax chases her away and you can feel at the helm again.He will calm you down so much that you can fall asleep exactly when you want! Cool? You no longer need to look at the ceiling until 3:30 in the morning, when your mind cannot calm down and you feel sick from your own thoughts. If you are afraid to come into contact with other people, Xanax will help too. It’s a great feeling when this weight is finally lifted from your shoulders, ”says another user.

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00:05 – August 4, 2017

Medical encyclopedias explain: “Xanax”, thanks to the active active ingredient alprazolam, allows you to almost instantly relax, relieve tension, suppress feelings of fear, anxiety and anxiety.You can quickly throw a small pill under your tongue at the end of the working day and instantly forget about a strict boss and endless reports.

It would seem that miraculous properties provided the explosive popularity of alprazolam, invented in the 1960s: today, more than five percent of the US adult population takes relaxation pills; it is included in the list of the most commonly prescribed drugs in the country.

Tablets do work, but they have a number of unpleasant features.First, tolerance to Xanax develops very quickly – to achieve the same relaxing effect, the body needs more and more alprazolam. Secondly, with uncontrolled intake, addiction develops over time. Third, it lowers breathing and heart rate – and when taken with opioid drugs (such as heroin or the equally popular fentanyl), the likelihood of death increases dramatically. Up to a third of all Xanax-related deaths are due to co-administration with opioids.

In addition, unlike many other substances, which in case of an overdose simply “knock out” the body, benzodiazepines act differently: they erase memory, leaving the ability to act. Those who have gone through Xanax can wander the streets for hours, attack people, rob and steal, get behind the wheel and arrange accidents. Someone in such a helpless state himself becomes a victim of scammers and rapists.

Benzodiazepines help people cope with the ruthless rhythm of life

Photo: Spencer Platt / Getty Images

Xanax is also known for the monstrous withdrawal syndrome after long-term overdose.Reddit users share: “I had visual hallucinations, I felt crazy, this is a constant bad trip (a slang expression for a psychedelic crisis – approx. Lenta.ru ). There were blows in my head, I almost had an attack twice. I heard a loud bang in my head, saw a bright flash, the body jerked sharply, but nothing happened. As if a flash grenade had exploded in my head. Fuck how scary. ”

“Dude, sounds tough. Sometimes I have flashes in my head in a dream, my body twitches so hard that I either bite my tongue or kick the cat so that it flies out of bed… And that’s four years later. This is not a joke, “another user answered him, admitting that now, due to the addiction of the past, he cannot fall asleep without sleeping pills.

In the topic of the forum of drug users, where the problem of refusal from certain substances is discussed, benzodiazepines (the common name of drugs like “Xanax”) won by a huge margin: 244 votes for them against 91 for methadone and 88 for heroin. Then, nevertheless, there is a “cancellation” of a similar severity: refusal from alcohol in those suffering from long-term severe alcoholism.

“I’m sweating because I don’t care about life; I hear voices in my head, they say: “stop”, but I found some Xanax in bed, drank this shit and went to bed again, “- rapper Lil Peep openly wrote about his addiction to the drug. When he dies in November 2017, traces of Xanax and Fentanyl will be found in his blood. Substances similar to alprazolam – benzodiazepines – have been found in the bodies of Elvis Presley, Michael Jackson, Heath Ledger and Whitney Houston.

Even the image of the Xanax tablet has entered popular culture – a tablet divided into four parts with the letters X-A-N-A-X.The pill cake was ceremonially cut by rapper Lil Pump after gaining a million followers on Instagram.

A XAN cake for celebration
Last year this time I was a nobody now I’m rich bitch ESSKEETIT

Btw I put 500 xanz in my cake

Photo posted by @lilpump

The seemingly “pure” rapper Drake also talked about his love for benzodiazepines: visiting iLoveMakonnen, he boasted that he was “throwing himself in curses”. Then, however, he made excuses that he only embellished the truth: “I don’t drink this shit, but you do”.

Related materials

00:05 – August 4, 2017

Xanax gave rise to a whole direction of “soundcloud rap”, so named because of the love of “relaxed” musicians to upload their creations to the SoundCloud resource. Writers in this style discuss depression and pain relievers to the accompaniment of musical rumblings.

Jewelry in the form of Xanax tablets is also available on the popular Etsy site: you can choose from earrings, pendants, rings and bracelets.

The history of benzodiazepines, if desired, can be traced back to Nazi times: in 1941, the Germans threatened to occupy Switzerland, and the pharmaceutical company Hoffman-LaRoche (now Roche), based in Basel, sent several Jewish employees to the United States.Among them was the chemist Leo Sternbach, who headed the company’s American headquarters and laboratory in New Jersey.

Xanax has firmly entered world culture through films, books and music

Shot: Fight Club film

“I have a full Xanax stomach. I drank everything in the bottle. I’m afraid it could be too much. ”- Marla, heroine of the movie“ Fight Club ”.

In 1955, in the same place, in New Jersey, Dr. Frank Milan Berger accidentally synthesized a drug called Miltown, which can be considered the predecessor of Xanax, during laboratory research of a muscle relaxant.“It allowed me to work well and make money, and also played a social role: making decisions, being confident and staying in control,” wrote Andrea Ton in The Age of Anxiety: The Story of America’s Turbulent Romance with Tranquilizers.

Then the Cold War was raging with might and main: while the children were learning to hide under their desks from Soviet atomic bombs, their fathers accepted miltown and, gritting their teeth, went to work. The pill became popular with women too: Tiffany & Co even released a diamond-encrusted pill box.

In 1963, Roche developed its own answer to the famous drug – Valium – and launched an active advertising campaign aimed primarily at women. They were encouraged to forget about stress, mood swings and romantic distress with one convenient pill. In 1970, a commercial was released, the heroine of which – teacher Miss Raymond – suffered greatly from menopause, but Valium helped her to recover.

Valium became a real hit: it was the first drug in history to be sold for $ 100 million.Nevertheless, over time, they started talking about its harmful properties. In 1975, an article appeared in Vogue magazine “Danger! Valium – your favorite pill can become your enemy! ” It said that addiction to newfangled drugs can be worse than heroin. In the same year, the US authorities limited its circulation and introduced penalties for illegal trade. They began to register it twice less often than before.

American medical advertisement of Valium

Valium did have dangerous side effects.It was slowly eliminated from the body, its traces were found even a few days after ingestion. Valium users often became zombie-like. “You don’t feel warmth, love, you can’t cry, feel tastes, smells,” wrote Barbara Gordon in her book about getting rid of addiction “I Dance As Faster As Possible”.

Xanax changed everything: chemists were able to deduce the formula of a drug that had a similar effect, but was excreted from the body in a matter of hours. The new drug was planned to help fight panic attacks, but consumers quickly found out that it is also suitable for everyday tasks: surviving a family holiday, lunch with a boss or an important meeting.The pill was often substituted for a visit to a psychotherapist.

Valium was touted as an effective and convenient tool

Photo: Daily Herald Archive / NMeM / Globallookpress.com

Sometimes there was nothing wrong with it – Harvard epidemiologist Ronald Kessler believed that if a person faced a big problem (for example, went bankrupt or took his child to the war), you can take a pill of alprazolam: “This is no longer a field of science, but sometimes a pharmacological solution is exactly what you need.”

However, modern life provides dozens of reasons to worry: the sensation-hungry media and couch scientists predict a deadly threat from wireless Internet, mobile phones, genetically modified products – no one bothers, for example, that the safety of GMO products is recognized by the entire scientific community. But what if? To cope with all this heap of problems, a pill with five letters most often helps.

Stephen Hayes, a psychologist at the University of Nevada, believes that benzodiazepines perform an interesting function – compensating for the evolutionary shortcomings of the homo sapiens species.The world is developing too fast, and a person is simply not equipped to cope with all of its challenges. This is where the achievements of modern pharmaceuticals come to the rescue.

However, the main victims of anti-anxiety drugs are not Hollywood stars at all, but ordinary Americans. “Anxiety helps me to do my job better. A little anxiety makes me a good worker, albeit a slightly less happy person. I am afraid that I would be lazy if I were not in constant fear that I would become a loser or that I would be fired, ”an employee of a prestigious PR company told NYMag.

The use of recognizable pills for many residents of the country has become a completely innocent habit: as, for example, a glass of wine at dinner or a glass of beer with friends. If full-fledged antidepressants need to be taken as a course, and the effect can be felt only after two to three weeks, with Xanax everything is easier: worried – ate a pill – calmed down. Xanax has become comparable to a cup of coffee, and it costs about the same.

Interestingly, the craze for Xanax and Valium often occurs among Americans who eat organic food, run in the morning, try vegetarianism and even refuse to vaccinate their children in a fit of madness.

Doctors are also happy to try: seeing the suffering of patients, they willingly prescribe higher doses of alprazolam. According to medical reports, benzodiazepines are now taken by more than five percent of the US adult population – that is, more than 12 million people.

Illegal trafficking in benzodiazepines is usually severely punished

Photo: Mohammad Ismail / Reuters

At the same time, from 10 to 25 percent of this number are dependent on the drug and cannot stop taking it: abrupt refusal causes terrible panic attacks.The statistics are also not encouraging: between 1996 and 2013, the number of prescribed prescriptions increased by 30 percent, and the volume of prescribed drugs doubled.

According to the US authorities, in 2015 more than 9 thousand people died from an overdose of benzodiazepines – that is, 24 people a day.

Anxiety professionals such as University of Nevada psychologist Stephen Hayes are increasingly turning to a new method of ‘acceptance therapy’. Instead of suppressing anxiety, they believe, they need to take it for granted, preventing it from taking control of emotions, demonstrating Buddhist calmness, and moving on.

In the end, stress motivates not to sit still, but to do, go, achieve and achieve. Suppressing even the beginnings of anxiety with endless Xanax pills, a person runs the risk of joining the ranks of those who are unlucky – who will enter the daily mournful list of 24 interrupted lives.

Meanwhile, Xanax and Alprazolam need not be feared – these affordable and extremely effective pills are the gold standard for the treatment of panic attacks, which in no case should be left without medical attention.The abuse of benzodiazepines creates the image of Xanax as another semi-legal drug to get high, but first of all, it is an indispensable drug that can help tens of thousands of patients and, when used in a controlled manner, is absolutely safe.

Xanax: side effects, drug information

(Continued from page 1 …) How to use Xanax Alprazolam has become a tablet, an extended release tablet, a dissolving tablet (tablet that dissolves quickly in the mouth) and a concentrated solution (liquid) to take by mouth 11 Xanax should be taken by mouth as directed by your doctor.

Dosage is based on the following factors: 2 Disease Age Response to treatment.

The dosage of Xanax may be gradually increased until the drug works effectively on the patient. The doctor’s instructions must be followed closely to reduce the risk of side effects. If this medication has been used regularly for a long time or in high doses, withdrawal symptoms (such as seizures) may occur if use is suddenly stopped.

To prevent these reactions, the doctor may reduce the Xanax dosage gradually.Xanax is available in doses:

0.25 mg – white, oval, won, imprinted “XANAX 0.25” 0.5 mg – peach, oval, won, imprinted “XANAX 0.5” 1 mg – blue, oval, won, imprinted “XANAX 1.0” 2 mg – white, oblong, multi-sided, imprinted with “XANAX” on one side and “2” on the back.

Do not crush, chew, or break Xanax Extended Release Tablet. Swallow the whole tablet. It is especially made to slowly release the medicine in the body.Breaking the pill would cause too much of the drug to be released at the same time 5Do not share your medicine with other people.

This may not work for them and may harm them. What happens if I miss a dose?

If you miss a dose of Xanax, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take additional medicine to make up the missed dose 5What happens if I overdose?

Manifestations of alprazolam overdose include drowsiness, confusion, impaired coordination, decreased reflexes, and coma.Death has been reported in association with alprazolam overdose alone, as it has with other benzodiazepines. 4 If a Xanax overdose occurs, call your doctor or 911. Seek urgent medical attention or call the Poison Hotline at 1-800-222-1222.5

Storage Xanax should be stored at controlled room temperature, 20 ° to 25 ° C. Precautions Changes in absorption, distribution, metabolism and excretion of benzodiazepines have been reported in a variety of states and populations such as: 4

Chronic alcoholism Alcoholic liver disease

Decreased hepatic function Decreased renal function Elderly patients

Obese patients.Allergies Do not use Xanax if you are allergic to alprazolam or other benzodiazepines such as chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax). 5

Alcohol Do not drink alcohol while taking Xanax. Xanax can increase the effects of alcohol 5 Pregnancy

Xanax is in the FDA pregnancy category D. Do not use Xanax if you are pregnant. Benzodiazepines can potentially cause fetal damage when applied to pregnant women.Xanax is believed to be similar to other members of the benzodiazepine class and is capable of causing an increased risk of congenital anomalies when administered to a pregnant woman during the first trimester.

Benzodiazepines, including Xanax, can potentially cause fetal harm when given to pregnant women. Use of Xanax during the first trimester of pregnancy should generally be avoided. Patients should be advised that if they become pregnant during therapy or intend to become pregnant, they should talk to their doctors. about the desirability of discontinuing the drug 4 A child born to a mother receiving benzodiazepines may be at some risk for drug withdrawal during the postpartum period.

In addition, respiratory problems have been reported in infants born to mothers receiving benzodiazepines.4 Care Similar to alprazolam due to other benzodiazepines, Xanax is assumed to undergo the transplacental passage and that it is excreted in human milk 4 Chronic diazepam (another benzodiazepine lactating agent) caused their babies to become lethargic and lose weight. As a general rule, mothers who are to use Xanax should not take care 4Children

Alprazolam has not been studied in the pediatric Safety and efficacy of Xanax 4 patients in people below 18 years of age has not been established.Gender Gender has no effect on pharmacokinetics (the process by which a drug is absorbed, distributed, assimilated and eliminated by the body) alprazolam. 4

Elderly Seniors may be more sensitive to the effects of benzodiazepines. They show higher plasma alprazolam concentrations due to reduced drug clearance compared to younger populations receiving the same doses.4 The calming effects of Xanax may last longer in the elderly.

Accidental falls are common in elderly patients taking benzodiazepines.Exercise caution to avoid falling or accidental injury while you are taking Xanax 5 Race Maximum Concentrations (the peak concentration that the drug reaches in the specified compartment after the drug has been administered and before the second dose is prescribed) and half-life (time required for drug concentration to reach half of its original value) are approximately 15% and 25% higher in the Asian population compared to the white population 4 Smoking

Alprazolam concentrations can be reduced by 50% in smokers compared to non-smokers.4 Suicide As with other psychotropic medications, the usual precautions regarding drug use and prescription size are indicated for severely depressed patients or those in whom there is reason to expect latent suicidal thinking or plans. Panic disorder has been associated with primary and secondary major depressive disorders and increased suicide rates among untreated patients 4

Episodes of hypomania and mania have been reported in association with the use of Xanax in depressed patients 4 Effect of uric acid excretion agent (causing urinary uric acid excretion) Alprazolam has a weak uric acid excretion agent.

Although other low-potency drugs have been reported to cause acute renal failure, there have been no reported cases of acute renal failure attributable to therapy with Xanax.

Alprazolam is primarily eliminated from the body by metabolism via cytochrome P450 3 A (CYP3A). Most of the interactions documented with alprazolam are with drugs that inhibit or induce CYP3A4.CYP3A4 is an essential enzyme in the body, mainly found in the liver and intestines.

Its purpose is to oxidize small foreign organic molecules (xenobiotics) such as toxins or drugs so that they can be removed from the body. Potent CYP3A inhibitors can increase plasma concentrations of alprazolam. Drugs that have this effect include:

Ketoconazole Itraconazole Nefazodone

Fluvoxamine Erythomycin Tagamet

HIV protease inhibitors, eg ritonavir.Benzodiazepines, including alprazolam, have additional central nervous system depressant effects when used in conjunction with:

Other psychotropic drugs Anticonvulsants Antihistamines

Ethanol Other drugs that produce central nervous system depression Other drug interactions include: Digoxin – Increased concentrations of digoxin have been reported when alprazolam was given, especially in the elderly over 65 years of age

Imipramine and desipramine – increased plasma concentrations of imipramine and desipramine by 31% and 20%, respectively Fluoxetine – coadministration of fluoxetine with alprazolam increased the maximum plasma concentration of alprazolam by 46%, decreased clearance by 21%, increased half-life of proxyphene – propoxyep co-administration reduced the maximum plasma concentration of alprazolam by 6%, decreased clearance by 38%, and increased half-life by 58% Contraceptive pills – coadministration of contraceptive pills increased the maximum plasma concentration of alprazolam by 18%, decreased clearance by 22%, and increased half-life by 29 %.

Studies on benzodiazepines other than alprazolam suggest possible drug interactions with alprazolam for the following: Diltiazem

Isoniazid Antibiotics such as clarithromycin (Biaxin), erythromycin (EES, EryPed, Ery-score, Erythrocin, Pediazole), rifabutin (Mycobutin), rifampicin (Rifadin, Rifater, Rifamate), rifapentin) or

Grapefruit juice Sertraline Paroxetine

Ergotamine (Cafergot, Ergomar, Migergot) Cyclosporine (Gengraf, Neoral, Sandimmune) Heart or blood pressure medication such as amiodarone (Cordarone, Pacerone), diltiazem (Tiazac, Cartia, Cardizem), nicardipine (Cardene), nifedipine, Procardia), or quinidine (Quin-G) Dexamethasone (Cortastat, Dexasone, Solurex, DexPak)

Imatinib (Gleevec) St.


Antifungal treatments such as miconazole (Oravig) or voriconazole (Vfend) Antidepressants such as fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), desipramine (Norpramin), imipramine (Janimine, or Tofraniturate), such as imipramine (Janimine, or Tofraniturate) butabarbital (Butisol), secobarbital (Seconal), pentobarbital (Nembutal) or phenobarbital (Solfoton)

Seizure medications such as carbamazepine (Carbatrol, Equetro, Tegretol), felbamate (Felbatol), oxcarbazepine (Trileptal), phenytoin (Dilantin), or primidone (Mysoline).This list is not complete and there may be other drugs that can interact with Xanax.

Tell your doctor about all medications you are using. This includes over the counter, vitamin and herbal products. Do not start a new medication without telling your doctor.

Xanax addiction and withdrawalIt is important to narrow Xanax gradually; otherwise there is a risk of benzodiazepine withdrawal. To discontinue treatment, the patient’s dosage of Xanax should be reduced and tapered slowly.Because of the danger of withdrawal, abrupt discontinuation of treatment must be avoided.

It is suggested that the daily dosage of Xanax be reduced by no more than 0.5 mg every three days. Reported withdrawal symptoms of Xanax discontinuation include: 4 Withdrawal symptoms can be suffered when Xanax is discontinued. These symptoms can include insomnia, lightheadedness, anxiety, fatigue, and headaches.

Insomnia, Nausea, Anxiety

Fatigue and fatigue Pathological involuntary movement Headache

Nausea / vomiting Sweating Diarrhea

Weight loss Decreased appetite

Tachycardia Reduced salivation Irritability Cognitive impairment

Blurred vision Muscle twitching Decreased coordination Disorders of muscle tone

Weakness Memory impairment Depression

Confusional state.Alprazolam is a safe and effective treatment when used as directed 13

Ativan vs. Xanax. What is the difference?

Ativan (lorazepam) and Xanax (alprazolam) are benzodiazepines (commonly called benzos) used to treat anxiety disorders. Xanax is also prescribed for panic disorder. Both drugs work by potentiating the action of the neurotransmitter GABA in the brain and are unsafe during pregnancy.

Studies have shown that both drugs show comparable efficacy and are prone to overdose and withdrawal symptoms. The difference lies in side effects, drug interactions, and indications based on the patient’s medical history. Although both drugs can have several side effects, at times ativan, i.e. lorazepam, is known to have the exact opposite of the desired effect, especially in the elderly.

Comparison table

Comparison table of alprazolam and lorazepam

Alprazolam lorazepam
Trade names Xanax Ativan 9003

Ativan and others for acute symptoms disorders, panic disorders, anxiety caused by depression

Lorazepam is used to treat anxiety disorders
Pregnancy cat. D (US) [Unsafe during pregnancy; see article for details] D (US) [Unsafe during pregnancy; see article for details]
Dependency High (addictive) High
Half-life Immediate release: 11.2 hours; Extended release: 10, 7-15, 8 hours 9-16 hours
Side effects Drowsiness, dizziness, blurred vision, headache, memory problems, concentration problems, sleep problems, limb swelling , muscle weakness, imbalance and coordination, slurred speech, indigestion, nausea, vomiting, sweating, dry mouth, etc.D. Drowsiness, dizziness, irritability, loss of coordination, difficulty concentrating, dry mouth, increased salivation, changes in libido and appetite, nausea, constipation, weight changes, frequent urination.
Limitations Should not be used by people with narrow-angle glaucoma or taking Sporanix or Nizoral. Allergy to benzodiazepines such as alprazolam, clonazepam, diazepam. May have the opposite effect on older people.
excretion renal renal
Bioavailability 80-90% 85% of oral dose
Legal POM (UK) Schedule IV (USA) Schedule IV CA) CD (Benz) POM (UK) Schedule IV (USA)
metabolism Hepatic, via cytochrome P450 3A4 Liver glucuronidation
CAS number 28981-97-7 846-49 -1
Formula C17h23ClN4 C15h20Cl2N2O2


Ativan (generically called lorazepam) is a class of benzodiazepines used to treat anxiety disorders.Ativan comes in 0.5 mg tablets, 1 mg tablets, 2 mg tablets, and liquid. Lorazepam Intensol is also marketed under the Ativan brand.

Xanax (the generic name for alprazolam) is a class of benzodiazepine drugs used to treat anxiety and panic disorders. Xanax is available in 0.5mg and sustained release tablets, 1mg and sustained release tablets, 1mg capsules, 2mg and sustained release tablets, 3mg and extended release tablets , for oral administration.disintegrating tablets and liquids.

Instructions for use

Ativan should be taken orally with or without food at the same time every day. The drug can take several hours to several days to take effect after the first start.

Xanax should also be taken by mouth with or without food. The extended-release tablets should not be crushed or divided, as this releases all of the medication at once. Xanax can also take hours to days to get up and running after the first launch.

Storage location

Ativan and Xanax should be stored at room temperature, away from light and moisture. The shelf life of Ativan is two years and Xanax is three years.

How It Works

Both Ativan and Xanax enhance the action of GABA, a natural chemical in the body that acts on the brain and central nervous system to cause a calming effect.


Studies [1] [2] comparing the efficacy of alprazolam and lorazepam showed that both drugs showed the same efficacy in reducing panic attacks and phobic behavior and much higher efficacy compared to baseline placebo.

Side Effects

Common side effects of Ativan include drowsiness, dizziness, loss of coordination, headache, nausea, blurred vision, change in sexual interest or ability, constipation, heartburn, or changes in appetite. Serious but rare side effects include mental or mood changes such as hallucinations, depression, or suicidal thoughts; slurred speech or difficulty speaking; changes in vision; unusual weakness; trouble walking; memory problems; signs of infection, such as fever or persistent sore throat; breathing problems, especially while sleeping; severe skin rash; yellowing of the skin or eyes; or an irregular heartbeat.

Common Xanax side effects include drowsiness, dizziness, headache, fatigue, dizziness, irritability, talkativeness, difficulty concentrating, dry mouth, increased salivation, changes in sex drive or ability, nausea, constipation, changes in appetite, weight changes. difficulty urinating or joint pain. Serious but rare side effects include shortness of breath, seizures, seeing things or unheard of voices, severe skin rashes, yellowing of the skin or eyes, depression, memory problems, confusion, trouble speaking, unusual changes in behavior or mood, thinking about hurting or killing yourself or trying to do it, or problems with coordination or balance.

Precautions and contraindications based on medical history

Patients are advised to give a detailed medical history to their doctors before taking Ativan. Special mention should be made of kidney or liver disease, glaucoma, breathing or lung problems such as sleep apnea, mental disorders or mood disorders such as depression and drug or alcohol abuse. Ativan can cause allergic reactions in people who are allergic to other benzodiazepines such as alprazolam, clonazepam, or diazepam.Sometimes Ativan can have the exact opposite of its intended effects on the elderly.

Patients must provide a detailed medical history to their doctors before taking Xanax. Special mention should be made of serious lung or breathing problems such as COPD and sleep apnea, liver disease, kidney disease, glaucoma, and drug or alcohol abuse. Xanax can cause allergic reactions in people who are allergic to other benzodiazepines such as alprazolam, clonazepam, or diazepam.The elderly may be more sensitive to the side effects of the drug.

Allergic reactions

Patients should immediately inform their doctors if they experience any of the following allergic reactions while taking Ativan: hives, difficulty breathing or swelling of the face, lips, tongue or throat.

Patients taking Xanax should tell their doctor immediately if they experience any of the following allergic reactions: rash, itching or swelling, severe dizziness, or trouble breathing.

Withdrawal symptoms

People may experience withdrawal symptoms if they suddenly stop taking Ativan or Xanax. Therefore, it is recommended to gradually reduce the dosage (usually 0.5 mg every three days).

Withdrawal symptoms for Xanax include seizures. Withdrawal symptoms include seizures, sleep problems, mental or mood changes, nausea, vomiting, diarrhea, loss of appetite, abdominal pain, hallucinations, numbness or tingling of the arms and legs, muscle aches, heart palpitations, short-term memory loss, very high fever, and increased reaction to noise, touch, or light.Learn more about Ativan withdrawal symptoms in this video:


An overdose of Ativan can lead to confusion, slow reflexes, clumsiness, deep sleep and loss of consciousness. An overdose of Xanax can cause drowsiness, confusion, coordination problems, and loss of consciousness.

Drug Interactions

Ativan may have adverse effects when interacting with certain drugs: antihistamines; digoxin or lanoxin; levodopa, found at Larodopa and Sinemet; medicines for depression, seizures, pain, Parkinson’s disease, asthma, colds, or allergies; muscle relaxants; oral contraceptives; probenecid or benemid; rifampin or rifadin; sedatives; hypnotic; theophylline or Theo-Dur; tranquilizers; and valproic acid, or depaken.

Xanax interacts poorly with amiodarone found in cordarone and paserone; antidepressants such as desipramine, imipramine, and nefazodone; antifungal drugs such as fluconazole, posaconazole, or voriconazole; antihistamines; cimetidine or tagamet; clarithromycin or biaxin; cyclosporine found in Neoral and Sandimmune; diltiazem, found in cardisem, dilacor, and thiazak; ergotamine, found in kafatin, kafergot, and vigraine; erythromycin found in EES, E-Mycin, and erythrocin; isoniazid found in INH and nidrazide; medications for mental illness, chronic pain, and seizures; nicardipine or cardin; nifedipine, found in Adalat and Procardia; oral contraceptives; propoxyphene or darvon; selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine, fluvoxamine, paroxetine, and sertraline; sedatives; hypnotic; and tranquilizers.



Alprazolam (Xanax) and clonazepam (Klonopin) are drugs that slow down the human central nervous system (CNS). They belong to a family of drugs called benzodiazepines. Doctors usually prescribe them to treat anxiety and panic disorders.

Xanax is most commonly used as a sleeping pill.Pharmaceutical company Upjohn created this drug in 1969 and doctors now prescribe over 50 million Xanax prescriptions every year.

Clonazepam, among other things, may help in the treatment of seizure disorders. It is an anticonvulsant and antiepileptic agent. Doctors may also prescribe clonazepam for panic disorder.

Xanax and clonazepam affect the central nervous system and may be misused, with some people becoming dependent on them.

What are people using them for?

Xanax is a useful medicine for people experiencing panic attacks.It helps relieve symptoms and reduce the frequency of attacks.

Some doctors prescribe Xanax for depression, but there is limited evidence to suggest it is effective unless the person is anxious.

Clonazepam is also a benzodiazepine. Doctors use it to treat seizure disorders in both adults and children. It can help correct chemical imbalances in the brain and reduce the number of panic attacks.

Taking clonazepam increases the level of gamma-aminobutyric acid (GABA) in a person, a chemical that sends signals to the central nervous system.

Lack of GABA activity can make people anxious and lead to panic attacks or seizures. Increasing the activity of GABA in the body helps to reduce the incidence of panic attacks and seizures.

What is the difference?

At first glance, Xanax and clonazepam are very similar. Both drugs are benzodiazepines, CNS depressants, and anxiety or panic attacks.

Both are short-acting drugs, but clonazepam stays in the body longer than Xanax.The half-life of Xanax is 6-25 hours, and for clonazepam it is 22-54 hours.

Clonazepam can also treat seizures, while Xanax cannot. Both drugs are used in different ways, not as intended, which will be discussed in more detail in the following sections.

Dosage comparison

Dosages usually differ depending on the person and the condition the doctor is trying to treat.

Dosage for clonazepam

For panic and anxiety, the adult dose is 0.25 milligram (mg) twice daily.

The doctor may increase the dose in 0.125 mg increments to 0.25 mg every 3 days until the panic disappears. However, the maximum dosage usually does not exceed 4 mg per day.

For convulsions, the dosage for adults is 0.5 mg 3 times a day. The doctor may increase the dose in 0.5 mg to 1 mg increments until the attacks are under control. The maximum dosage should not exceed 20 mg per day.

Xanax dosage

For anxiety disorders, the adult dosage usually starts at 0.25–0.5 mg three times a day.The doctor may gradually increase the dosage for maximum effect. However, the maximum dosage usually does not exceed 4 mg per day.

In panic disorder, the required dose of Xanax may exceed 4 mg per day.

Controlled trials involving 1,700 people showed Xanax to be effective for panic disorder when participants received 1-10 mg daily.

Dosage change

Regardless of whether he prescribes clonazepam or Xanax, the doctor usually starts with the lowest possible dosage, regularly reviews the dosage and considers reducing it, for example, if the panic attacks stop.

If the doctor advises to reduce the dosage, he should make sure that the person does it slowly. If a person stops taking any drug abruptly, it can cause withdrawal symptoms.

Both xanax and clonazepam usually begin to work a few hours or days after starting the medication.

A dose of Xanax acts on a person for several hours. A dose of clonazepam can last about three times as long.

Benzodiazepine dependence

Long-term use of benzodiazepines can lead to dependence on these drugs.Addiction can begin after 1 month of using the medication.

Because Xanax stays in the body for less time than clonazepam, it may carry a higher risk of overuse or misuse, which can lead to dependence.

It is very important that the person does not suddenly stop taking any of the drugs. This can lead to side effects such as life-threatening seizures as well as withdrawal symptoms.

A physician or pharmacist should closely monitor how a person uses benzodiazepines to reduce the risk of dependence.

Shape comparison

Clonazepam is available in the form of oral tablets that the person swallows. There is also a version that dissolves in the mouth.

Xanax is available as immediate and extended release oral tablets and oral solution.

Side effects

These drugs can have a number of side effects. These will be discussed in more detail in the sections below.


Some of the more common side effects of clonazepam include:

  • drowsiness
  • staggering movements and unsteady gait
  • dizziness
  • depression
  • fatigue
  • memory problems
  • noses 90,728 90,728 constipation or diarrhea

  • If any of these side effects develops, the person should talk to their doctor.

    Some of the rarer and more serious side effects of clonazepam include:

    • depressed mood or suicidal thoughts
    • seizures, especially if the person suddenly stops taking the drug
    • hallucinations
    • mood and behavior changes
    • sweating
    • abnormal eye movements
    • Anxiety
    • Difficulty speaking
    • Insomnia
    • Excessive bleeding and bruising due to low platelet count
    • Menstrual problems
    • Difficulty urinating

    Any of these side effects require immediate medical attention.


    Some of the most common side effects of Xanax include:

    • drowsiness and fatigue
    • lightheadedness
    • headaches
    • nausea
    • dry mouth
    • irritability
    • becomes talkative 90,729 with forgetfulness 90,729
    • Difficulty urinating
    • Constipation
    • Joint pain
    • Appetite changes
    • Weight changes
    • Sexual dysfunction

    If any of these side effects develops, the person should make an appointment with a doctor.

    Some of the rarer and more serious side effects of Xanax include:

    • yellowing of the skin or eyes
    • difficulty in speaking
    • poor coordination and balance
    • seizures
    • mood changes
    • hallucinations
    • confusion or memory problems
    • depression or suicidal thoughts
    • severe rash

    A person needs immediate medical attention if any of these side effects develop.

    Since both Xanax and clonazepam can cause drowsiness and poor coordination, people taking these drugs should be careful about driving and using machinery.

    A severe allergic reaction is unlikely with any drug. However, if a person develops any reaction symptoms such as a rash, difficulty breathing, itching or swelling, they need urgent help.


    People taking Xanax or clonazepam should not mix them with alcohol or opioids.This can cause dangerous side effects that can be fatal.

    Other CNS depressants may also interact with Xanax or clonazepam and alter their mode of action. Such changes can also lead to serious side effects.

    Some other CNS depressants include:

    • hemp
    • antihistamines
    • sedatives and hypnotics
    • tranquilizers
    • mood stabilizers
    • muscle relaxants
    • withdraw drugs
    • pain relievers

    tell your doctor or pharmacist about any other medicines they are taking or planning to take.

    Improper use

    An off-label use is a use that is not listed on FDA-approved packaging but for which a physician can prescribe a drug.

    Some off-label uses of Xanax include the following:

    • irritable bowel syndrome
    • essential tremor
    • tinnitus
    • depression
    • agoraphobia or fear of open spaces
    • premenstrual syndrome

    Some uses by appointment include the following:

    • burning mouth syndrome
    • essential tremor
    • depression
    • multiple sclerosis
    • periodic limb movement disorder
    • restless legs syndrome
    • tinnitus
    • Tourette’s syndrome
    • dizziness

    Which one is better to use?

    Although clonazepam and Xanax are similar drugs, there are times when it is better to use one than the other.

    Xanax is not a cure for seizures. Thus, a person trying to control and treat seizures may find clonazepam more helpful.

    People with anxiety disorders should make an appointment to discuss the various treatment options and the pros and cons of each.

    The doctor will ask about the patient’s symptoms and medical history. They will review all the medications a person is taking before advising on which prescription is most appropriate.

    Certain medications do not respond well to certain medications or they may not be effective. In this case, the person should talk to their doctor who can provide an alternative recommendation.

    Xanax and alcohol: compatibility, as long as possible, consequences trekrezan

    The joint use of alcohol with drugs is prohibited, especially the tranquilizer Phenazepam. Taking the drug with alcohol can be fatal.

    Preparation Phenazepam

    A tranquilizer is prescribed for problems with the central nervous system, since the active substance relieves stress, relieves fear, irritability and anxiety. Phenazepam is a medicine that can fight psychological and mental disorders.

    Now the drug can be purchased only by prescription, since the action of Phenazepam is based on inhibition of brain functions. According to experts, the drug causes a stable dependence, therefore, its intake is carried out only under the supervision of a doctor.During this, drinking alcohol is strictly prohibited.


    Phenazepam and alcohol, when used together, cause this condition:

    1. Poisoning. Taking alcoholic beverages with tranquilizers negatively affects the human brain. The most harmless consequence is the intoxication of the body and a severe hangover syndrome. In other cases, the side effects of the drug are sharply manifested: blurred consciousness, dizziness, nausea, increased fear, hallucinations, and increased suicidal tendencies.
    2. Drug addiction. Only a specialist can prescribe the dose of the drug and the course of its use.
    3. Euphoria. Drinking people seek to enhance the effect of alcohol and begin to take Phenazepam and alcohol together. Such a compound causes a person to feel ecstatic, but as a result, in addition to alcoholism, addiction to the drug develops. While taking such a “cocktail”, a person does not remember how much medicine he drank, sometimes a lethal dose of a substance is taken this way.You can manage to help a person, but often even resuscitation measures are not able to return life.
    4. Allergies, sometimes death. Each patient is individual, and no one can accurately predict what the body’s reaction to the drug will be.
    5. Coma. A large dose of Phenazepam with alcohol leads to coma and the chances of recovery are low. Alcohol enhances the effect of the tranquilizer, and intoxication develops rapidly.


    When the dose is exceeded, a borderline state sets in, and the following signs are noted:

    1. Phenazepam with alcohol affects the mental state and intensifies the state of depression, aggressiveness, misunderstanding of others comes.According to the reviews of people who sought to increase the influence of alcohol, they did not understand what they were doing and saying to others. Doctors have recorded many cases of suicide while taking Phenazepam and alcohol at the same time, since a person’s feeling of fear dulls and there is a certainty that no one needs it.
    2. The interaction of a tranquilizer with alcohol leads to malfunctions of the respiratory system, there are often cases of suffocation and respiratory arrest during sleep.
    3. After taking a cocktail of alcohol with Phenazepam, vomiting often occurs, if this occurs in a dream, then a person may choke.Many drinkers at this moment lose control over the situation and do not understand how to help themselves, and what is generally happening to them.
    4. Heart rhythm problems.
    5. Epileptic seizures and convulsions.
    6. A stupor occurs.
    7. In some cases, a person falls into a coma.
    8. Possible urinary retention or involuntary relaxation of the sphincters, resulting in urination.
    9. Decreased sexual activity.
    10. Delusional ideas are developing.
    11. Visual impairment occurs.
    12. Weight loss.
    13. Involuntary defecation.
    14. Blood pressure is falling.
    15. Phenazepam, after taking alcohol, affects attention and reaction, as a result of which performance is lost.
    16. A person becomes dangerous to others.
    17. With the constant intake of alcohol together with Phenazepam, a person becomes crazy.
    18. Drug addiction is developing.

    It should be borne in mind that alcoholic beverages should not be taken during treatment with Phenazepam.This list includes extracts and syrups even with a small percentage of alcohol in the composition. You can take alcohol no earlier than 48 hours after the last pill intake.

    Lethal dose

    Phenazepam and alcohol, when combined, give an unpredictable result, and no one can accurately predict how a person will behave after taking them. For each lethal dose is individual and depends on chronic diseases, the state of the immune system, the food taken and the presence of an allergy to one of the components of the “cocktail”.

    According to pharmaceutical research 7 ml. intravenously administered Phenazepam or 10 mg of a solid leads to an overdose and death. Even with timely and proper medical care, the chances of survival are minimal.

    Hangover and Phenazepam

    During a hangover, Phenazepam is dangerous, even despite the fact that it is prescribed for acute withdrawal symptoms. Reasons:

    1. Phenazepam in combination with alcohol is addictive.The addiction proceeds with a severe form of abstinence.
    2. Only a specialist has the right to prescribe a drug, the course of treatment is a certain scheme.
    3. Aftereffect syndrome occurs, the person loses his ability to work, becomes irritable and feels fatigue throughout the body.

    According to doctors, taking Phenazepam with a hangover is the way to a drug dispensary.

    Symptoms of poisoning

    There are several stages:

    1. Light poisoning – confused consciousness, impaired concentration, pupils do not react to light, drug intoxication, a person behaves inadequately, but at the same time makes contact.
    2. Moderate – Pupils stop responding to light and become very narrow. Reflexes are impaired, swallowing becomes difficult. A superficial coma may develop.
    3. Severe poisoning – atony is observed, reflexes are absent, reaction to pain is not observed. The person falls into a heavy coma. Breathing becomes superficially arrhythmic or completely absent. Tachycardia, hypothermia develops and blood pressure drops.

    At any stage, breathing and heart activity are impaired.

    Poisoning can have serious central nervous system effects even after recovery.

    First aid

    If a person took an alcoholic drink after Phenazepam, then it is necessary to provide medical assistance, which consists of the following:

    1. Immediately call an ambulance or take the patient to a medical facility on your own.
    2. If the person has not fallen asleep, carry out a gastric lavage.This requires drinking at least 6 glasses of water diluted with soda (the solution must be weak). Then press down on the base of the tongue to induce vomiting.
    3. Give some kind of sorbent, for example, activated carbon (calculation of 1 tablet per 10 kg), Polysorb, Enterosgel and the like.
    4. If a person has fallen into an unconscious state, in no case should he be left alone. Be sure to turn it to its side and fix the tongue (you can use the handle of a spoon wrapped in a bandage).

    An overdose of Phenazepam and alcohol should be treated only in a medical institution, it is impossible to do this at home.

    In the hospital, drugs are administered that weaken the effect of the tranquilizer on smooth muscles (drugs containing strychnine are used). Basically, they are injected intramuscularly three times a day.

    Alcohol is prohibited these days. Drinking alcohol is allowed only with the permission of your doctor.

    Similar entries

    Source: http: // apatii.net / farmakologiya / fenazepam-i-alkogol

    Phenazepam and alcohol – what will happen to the body?

    Home »Medicines» Phenazepam and alcohol …

    Phenazepam belongs to the group of the strongest tranquilizers, which have a sedative, hypnotic effect on the body, relieve anxiety. This drug expresses the strongest effect on the nervous system of the body.

    Today, phenazepam is increasingly being used together with alcohol.Doctors – resuscitators are worried about this because every day a lot of people get to them in serious conditions. This article tells about whether it is possible to drink phenazepam with alcohol, and what consequences this combination can have, we will reveal the topic of overdose and the compatibility of these components.

    Doctors unanimously speak of their complete incompatibility, because taking a tranquilizer with alcoholic beverages leads to serious and irreversible consequences. Moreover, how hard these consequences are borne by a person depends on the dose of alcohol, on how many pills were drunk and on the state of the body.


    • Phenazepam and alcohol taken together have a negative effect on the nervous system. Often there is an increase in effects such as: drowsiness, dizziness, loss of understanding of the current situation. Depression occurs, fear intensifies, suicidal urges occur.
    • The action of phenazepam with alcohol can cause problems with the respiratory system, which can lead to suffocation. There are cases of sudden complete cessation of breathing that occurs during sleep.
    • Shared use can induce vomiting during sleep, as a result of which death from flooding with vomit can occur. A person loses control over the environment and cannot provide himself with any help, even with a full understanding of what is happening to him.
    • Cardiac arrhythmias are common.
    • Against the background of a negative effect on the central nervous system, convulsions and epileptic seizures occur.
    • Often, against the background of the joint use of these funds, a coma occurs.
    • Phenazepam after taking alcohol causes a decrease in a person’s reaction, a decrease in performance, attention. The person becomes irritable, lethargic, sleepy. This combination leads to problems in the treatment of hangover syndrome.

    Phenazepam and alcohol – lethal dose

    The effect of tranquilizers and alcohol-containing beverages is considered unpredictable and it is impossible to calculate how this or that organism will behave in this combination. It depends on the characteristics of the person.

    For each person, the lethal dose is individual and directly depends on whether the person has chronic diseases, allergic reactions to any component that is part of the tablets or alcohol, whether the food was taken and its quality.

    Health professionals say 7 ml. intravenous administration of phenazepam or 10 mg. the solid form can lead to overdose and, to death, which occurs from respiratory arrest. Moreover, even with timely and correctly provided resuscitation assistance, the chances of survival in this situation are minimal.

    We examined how phenazepam interacts with alcohol, the consequences of this combination are extremely unfavorable for the body, and have many negative effects leading to death.

    Teturam alcohol tablets are not life threatening, but they cause terrible sensations. They are designed to help fight alcohol addiction. If a person taking teturam drinks alcohol, then he will be very bad!

    Source: https://saovxlam.ru/lekarstva/fenazepam-i-alkogol.html

    What are the side effects of drinking alcohol with Xanax? 2019

    Xanax is an anti-freeze vacation drug sold by Pfizer Inc., also sold in generic form under its chemical name, alprazolam. Classified as a benzodiazepine central nervous system deodorant, Xanax comes with a warning sign against drinking alcohol while taking it.

    Xanax is an anti-freeze dispensing medicine sold by Pfizer Inc., also sold in generic form under its chemical name, alprazolam. Classified as a benzodiazepine central nervous system deodorant, Xanax comes with a warning sign against drinking alcohol while taking it. This is because alcohol, another depressant, when combined with Xanax can cause many unsafe, even life-threatening, side effects.

    Mental and physical side effects

    Alcohol consumption while taking Xanax impairs brain function, according to Alprazolam.org and also interferes with the brain’s ability to communicate with the body.

    As a result, the combination can significantly interfere with mental alertness and physical coordination, leading to side effects including extreme drowsiness, unconsciousness, severe dizziness, and balance problems such as stumbling or daze.

    Consuming too much alcohol by itself can cause a person to “go out” or experience a period that they do not remember after sobering up.When Xanax is added to the mixture, the risk of this dangerous occurrence is greatly increased.

    Alcohol also enhances Xanax’s ability to cause confusion, significantly impair judgment, and produce unusual behavior, making drug use a prescription for a potentially disastrous experience.

    The Department of Health and Human Services claims that Xanax even replaced the Rohypnol benzodiazepine parrot with flunitrazepam, otherwise known as “Ruffies,” as a day rape drug in parts of the US due to the amnestic properties of Xanax when mixed with alcohol,

    The combination of two powerful central nervous system depressants can cause serious cardiovascular and respiratory side effects, NIDA reports.

    Alcohol and Xanax, when combined, slow down the heart rate as well as reduce the rate of breathing.

    This side effect is especially dangerous for someone who passes out from a soothing cocktail, as it can lead to respiratory failure.

    Dependency and Withdrawal

    Both alcohol and Xanax can cause physical and psychological dependence, and both can create withdrawal symptoms when abruptly stopped.Chronic use of two drugs at the same time can aggravate withdrawal symptoms for each drug, which include intense cravings for alcohol or Xanax, irritability, insomnia, hallucinations, and seizures.


    Drinking with Xanax should be avoided primarily because of the risk of a fatal side effect of the combination: overdose. Alcohol consumption while taking Xanax significantly increases the risk of overdose associated with alprazolam alone.

    Overdose can be identified by specific side effects that cause key symptoms, according to MedlinePlus.These include confusion, drowsiness, severe motor coordination problems, and coma.

    If any of these side effects happen to someone who has drunk alcohol while taking Xanax, it is imperative that you contact emergency services immediately.

    Source: https://ru.healthypasty.com/what-are-side-effects-of-drinking-with-xanax-17132

    Alprazolam – the most popular drug among young people or how to treat Xanax addiction?

    Oddly enough, but spice and “salt” are gradually disappearing into the past, making room for new psychoactive substances.On television, there are less and less reports about how people go crazy after Chinese drugs. Times are changing, and with them the drug market.

    Among young drug users, smoking mixtures are no longer quoted, and “salt”, having found its niche among consumers, unfortunately, has become the norm for many. The excitement is growing around a new drug known to many as Xanax or, scientifically, Alprazolam.

    Back to the past

    Among others, it is possible to note Marilyn Monroe, who, as many believe, died precisely from an overdose of barbiturates, or the charismatic leader of the immortal group The Doors, Jim Morrison, who died at the age of 27 from cardiovascular disease with complications resulting from a high dose cocaine and barbiturates.

    Later, barbiturates lost their relevance and opioids became fashionable, which could be easily found in pharmacies in the United States of the 90s. The best known of these are oxycodone, oxycontin, hydrocodone, and many codeine derivatives.

    Now it is more difficult to do it, but it is still quite possible. That is why in the media so often you can see articles about the fact that in the United States the opioid crisis is declared a national disaster.

    What now?

    Quite recently, at the peak of popularity in the States, there was the so-called “Purple drank” – a drink based on cough syrup with a strong narcotic effect from the main active ingredient codeine.

    In Russia, this type of drug has not taken root, because now it is very difficult to get pure codeine, especially to mix it and make syrups. Although you can find this on the black market for a huge price. Today, at the peak of popularity, the benzodiazepine tranquilizer alprazolam, better known under the trade name “Xanax”.

    Xanax does not disdain many western rappers, often using it and even composing their own tracks about it. From across the ocean, fashion has come to us: in Russia there are also hip-hop performers who praise this substance.And, as you know, the main audience of modern Russian benchmarks is young guys who love to experiment with different things.

    • Can’t persuade
      for treatment ?
    • We will help with motivation for treatment. As a rule, close people find it difficult to persuade or force the addict to be treated. World experts have developed EFFECTIVE schemes of motivation, using which, you can lead the addict to the decision to seek help. 8 (800) 333-20-07

    So what is alprazolam?

    And I must say that it copes with these goals perfectly: those who drink this medicine as prescribed by a doctor for, for example, stopping severe anxiety or panic attacks, remain satisfied.But is this substance so safe when uncontrolled systematic use for the sake of euphoria?

    It should be noted that all benzadiazepine tranquilizers have one of the most severe withdrawal symptoms, sometimes even surpassing opioids such as heroin. This means that if you use the same Xanax for a long time and constantly, you can get a very strong withdrawal syndrome or withdrawal symptoms.

    Acting on the psyche for a long time as a sedative, relaxing agent, when canceled, a number of extremely unpleasant symptoms appear, but the main thing is that a person can no longer fully function without this substance, as before.Here is what users of benzodiazepines like Xanax write about it on foreign forums:

    After 4-5 months of using benzodiazepines, I felt so bad that I began to hallucinate and feel insane, as if it was an endless “bad trip”. Brain zaps from benzodiazepines are even worse than from antidepressants, and a couple of times they even turned into full-fledged seizures.

    It was as if I heard a loud “BAM” sound, then I saw a flash of light, and my body began to beat in convulsions.That’s how it was! It was like a flash grenade was blown up in my head. Damn scary! ”

    Xanax overdose deaths

    Most notorious case in recent years: the death of rapper Gustav Ara, better known as Lil Peep. At the peak of his popularity, at 22, he was heavily addicted to drugs. Once, after mixing the potent synthetic opioid fentanyl with xanax, his breathing stopped because alprazolam significantly increases the depressing effect of other substances on the respiratory system, such as opiates or alcohol.

    Lil Peep is reported to have previously been a drug addict, addicted to cocaine and alprazolam; he regularly mentioned the topic of drugs in his texts and posts on social networks. In one Instagram post, Gustav declared himself a “productive addict” and called for drug withdrawal.

    Alprazolam in Russia

    What if a person uses Xanax?

    If you are sure that a person has problems with alprazolam or any other benzodiazepine tranquilizer, and he cannot cope on his own, he urgently needs the help of specialists.Every minute can cost your life, as long-term use of potent tranquilizers can lead to irreversible consequences in the work of the nervous system and the brain!

    If you or your loved one is addicted to tranquilizers, call us! We know how to help and return a person to normal life: 8 (800) 333-20-07!

    Source: https://www.czm.su/articles/alprazolam-samyy-populyarnyy-narkotik-u-molodezhi-ili-kak-lechit-zavisimost-ot-ksanaksa

    Xanax – addictive pharmaceutical drug – Narco Info

    Currently, there are a large number of drugs that have a stimulating effect on the human psyche and in the case of improper use, causing drug intoxication, and with regular use and strong dependence.

    These drugs include Xanax or Alprazolam. Currently, this medicine cannot be purchased in Russia, but its analogues are sold by prescription.

    Xanax is very popular abroad because it helps to relieve anxiety, eliminate panic attacks. It should not be forgotten that not all pills can cure.

    Uncontrolled, and even more so without special indications, the use of potent drugs that have an effect on the psyche, can cause damage to health.Xanax belongs to a group of so-called pharmaceutical drugs.

    Xanax Action

    Xanax is a tranquilizer drug used to treat neurotic conditions characterized by:

    • deterioration of the emotional state;
    • constant anxiety and fear;
    • bad sleep.

    This medication relieves depression, muscle cramps, anxiety. In this case, the drug should be prescribed by the doctor very carefully, starting with the smallest dose.

    Side effects

    Despite the fact that in some cases Xanax is a very effective drug that allows you to bring your psyche back to normal, it also has many side effects. And if a medicine is brought from abroad and the instructions for its use are written in a foreign language, then there is a danger of incorrect dosage.

    First, it causes drowsiness and slows down the reaction. It is very dangerous to use Xanax if you then need to drive a car yourself or work at a height.Also, the medicine can cause disorientation in space and impaired coordination of movements.

    • Secondly, this tranquilizer can cause euphoria, loss of a sense of danger, and as a result, inadequate perception of reality.
    • Third, an overdose of the drug manifests itself in the form of hallucinations, the appearance of a feeling of fear, outbursts of aggression and suicidal desires.
    • But, the side effects of Xanax negatively affect not only the human psyche, but also his physical condition.These include:
    1. Deterioration of the liver.
    2. Intestinal disorder.
    3. Profuse salivation.
    4. Nausea.

    Xanax as a drug

    Most tranquilizers are used by drug addicts to immerse themselves in a state of euphoria and an illusory world. Xanax is no exception. Its use without a doctor’s recommendation and in strict accordance with the established dosage leads to severe physical and mental dependence.

    Three months are enough for the development of addiction. And then it will be impossible to stop using the medicine on your own. Even in cases where a person uses Xanax to treat a disease, and addiction is observed, the use of the drug should not be stopped abruptly.

    This can cause severe depression and acute psychosis.

    Xanax and alcohol

    Xanax and its analogs must not be categorically mixed with alcohol. Their interaction leads to hallucinations, depression of consciousness, and even a drug coma.

    Only a doctor can help to cope with drug addiction and protect the patient’s body from side effects.

    Source: https://narko-info.ru/ksanaks-aptechnyj-narkotik-vyzyvayushhij-zavisimost/

    How long does Xanax (Alprazolam) stay in your system? – Addiction – 2019

    Xanax (alprazolam) is a benzodiazepine medication that is used to treat anxiety disorders, panic disorders, and panic attacks. It is also sometimes prescribed for depression and other conditions like agoraphobia and severe premenstrual syndrome.

    Xanax works by slowing down your nervous system, giving you a sense of calm. Because it can be addictive, it is used as a short-term treatment.

    You may want to know how long Xanax stays in your system so you can avoid side effects, interactions with other drugs and substances, and accidental overdose.


    Xanax is considered an intermediate-acting benzodiazepine drug.After taking Xanax in pill form, peak levels are found in your blood after 1 to 2 hours.

    The average half-life of Xanax in the blood in healthy adults is 11.2 hours, which means that half of the drug has been metabolized and excreted in the urine during this time.

    In order to clear the body from 98 percent of the dose of the drug, it takes five to seven half-lives, so it takes at least four days to completely remove Xanax from the body.

    Longer half-life for geriatric populations, obese people, people with alcoholic liver disease, and people with Asian genetics. This means Xanax takes longer to metabolize and cleanse your system. Meanwhile, the concentration of Xanax in the blood of smokers is reduced by 50%.

    Windows Discovery

    Xanax is found in your blood, urine, saliva and hair, but how long it takes depends on many individual factors. Your age, weight, body fat, other medications, dose, duration of Xanax intake, hydration level, and metabolism all affect the time it takes for the drug to be cleared from your system.

    Here is the approximate detection window time for Xanax:

    • Urine: A urine test for drugs such as those made for work will test positive for benzodiazepines within five days and up to a week after the dose. For populations that metabolize Xanax more slowly — the elderly, obese, Asian, and those with alcoholic liver disease — this time may be even longer.
    • Saliva: Xanax can be detected in saliva for up to 2.5 days.
    • Hair. Like all medicines, Xanax can be found in your hair two to three weeks after and up to 90 days after your last dose.
    • Blood. Blood levels can be done as a screening test or when treating a suspected overdose, but they can only tell if you have taken Xanax in the past 24 hours.

    If you are taking Xanax and have a screening or drug test, report it to the laboratory so they can interpret your results correctly.If you are being tested at work, you can tell your employer that you are taking Xanax ahead of time.

    There are certain potential risks when taking Xanax, including:

    • You may feel drowsy and drowsy when you are taking Xanax, so do not drive, operate equipment, or perform any other activity or task that requires full concentration.
    • Xanax may harm your fetus if you are pregnant, so talk to your doctor if you become pregnant or plan to become pregnant while taking Xanax.
    • Interaction with other medicines can lead to serious, life-threatening breathing problems, sedation and coma while you are taking Xanax. Talk to your doctor about all prescription and over-the-counter medications you are taking, plan to take, or plan to stop. Some drugs of particular concern include opiate drugs such as codeine, hydrocodone, fentanyl, hydromorphone, meperidine, methadone, morphine, oxycodone, and tramadol.
    • Drinking alcohol and / or using illegal drugs increases the likelihood of life-threatening side effects. You need to avoid alcohol and street drugs while you are taking Xanax.
    • Since Xanax can induce feelings of relaxation, calmness and well-being, and because it takes very little time for your body to tolerate the dose you are taking, it has the potential to develop a habit. Your doctor will likely prescribe the lowest dose for you to see how effective it is and keep you at the lowest effective dose.Make sure you are only taking Xanax as directed; do not take it more often, take a large dose, or continue to use it for longer than your doctor ordered.
    • You may experience withdrawal symptoms if you suddenly stop taking Xanax. Do not stop or reduce the dose yourself, as this can be dangerous. Talk to your doctor who will prescribe an appropriate narrowing schedule that will minimize or eliminate any possible withdrawal symptoms.

    Common side effects

    Xanax can cause side effects that often go away when your body gets used to the medication. The most common side effects include:

    • Drowsiness
    • Fatigue
    • Feeling dizzy
    • Dizziness
    • Headache
    • Dry mouth
    • Erectile dysfunction and / or other sexual performance or interest problems
    • Nausea
    • Constipation
    • Changes in appetite
    • Joint pain
    • Nasal congestion

    Tell your doctor if these side effects persist or are serious.

    Serious side effects

    Serious side effects are not very common, but if you experience any of the following situations while taking Xanax, call your doctor immediately:

    • Shortness of breath
    • Seizures
    • Hallucinations (hearing or seeing things that are not real)
    • Severe rash on your skin
    • Yellow eyes or skin
    • Memory problems
    • Difficulty speaking
    • confusion
    • Coordination problems
    • depression
    • Suicidal thoughts
    • Mood changes that are not normal for you


    Take your prescription on schedule and the dosage prescribed by your doctor.Do not cut or crush the extended-release tablets, as this will give you a large dose right away and may cause an overdose.

    Symptoms of a Xanax overdose may include:

    • Drowsiness
    • Shallow breathing
    • Sticky skin
    • Late students
    • Weak and fast pulse
    • confusion
    • coma

    If you suspect someone has taken an overdose of Xanax, call 911 or the Poison Control Center at 1-800-222-1222.

    Source: https://rus.psychic-parapsychologist.com/how-long-does-xanax-stay-your-system-63671

    Phenazepam and alcohol: consequences, compatibility, how much can you take

    Phenazepam is a psychotropic drug that affects brain cells, parts of the human central nervous system. The function of the drug is based on inhibition of the excitability of the central nervous system, inhibition of brain functions.

    It belongs to the group of tranquilizing substances. The active ingredient of Phenazepam – bromodihydrochlorophenylbenzodiazepine – relieves psychoemotional stress, eliminates anxiety and panic attacks.

    Has pronounced sedative, hypnotic and relaxing effects.

    The drug develops addiction, so it must be taken under the supervision of specialists.

    With prolonged use of the drug, people prone to headaches and increased anxiety become addicted.

    After taking the medicine, the patient is in a lethargic state and poorly oriented in space. As soon as the body adapts to the doses of Phenazepam, the reaction to the application stops.

    The drug is indicated for the treatment of disorders of the nervous system in people at any age. The medicine is prescribed for sleep disturbances, nervous disorders. Also in the case of panic attacks, the development of phobias and severe depressive and neurotic conditions. Phenazepam is used to treat nervous tics and VSD.

    Surpasses other benzodiazepine tranquilizers in terms of effectiveness. Has the form of release in the form of tablets or liquid consistency. Doctors prescribe a standard dosage of 0.5 mg 3 times a day.Patients with epileptic seizures should take 3-10 mg per day.

    Abstinence dependence is treated with a drug with a dosage of 5 mg per day. Systematic insomnia is eliminated after consuming 2 mg of the substance at bedtime. With serious psychoemotional disorders, an increase in dosage occurs.

    5 mg of a substance per 1 kg of weight is a lethal dose.

    Phenazepam and alcohol

    Alcohol reduces the excitability of cells and increases the feeling of euphoria like a narcotic substance.The appearance of a feeling of intoxication is explained by the presence in the body of the decay products of ethyl alcohol.

    With frequent alcohol abuse, neurons are damaged, the cardiovascular system and the gastrointestinal tract are susceptible to disorders.

    The simultaneous use of the drug with alcohol increases the effect of the substance on the body by 2 times.

    The interaction of Phenazepam with alcohol will lead to negative consequences for the body:

    • Severe inhibition, change in coordination of movement, vomiting.
    • The appearance of complicated shortness of breath with possible respiratory arrest.
    • Cardiac arrest.
    • Mental disorders: the development of suicidal tendencies, aggressive behavior.

    Incompatibility of Phenazepam with alcohol depresses the central nervous system, which entails critical consequences. A negative effect on the body should be a good reason to establish a categorical ban on such a combination.

    Phenazepam and beer

    The drug is contraindicated with both strong and low alcohol drinks.Even a small amount of alcohol, reacting with drug substances, can provoke an unexpected reaction. However, in addition to alcohol, beer contains carbon dioxide and fusel oils, which interact with the drug and increase the risk of poisoning.

    If you combine Phenazepam with beer, there is a risk of developing reactions:

    • Deep sleep, lasting 13-15 hours, accompanied by bouts of shortness of breath, coughing or choking.
    • Confusion and disorientation in space.
    • A day later, signs of a depressive state appear, which are difficult to deal with.
    • There is a risk of complications of the respiratory tract. If you try again to combine the drug with beer, an attack of suffocation with a fatal outcome is possible.

    In response to a combination of beer and medicine, you can provoke the strongest drug addiction, even if you take pills in small doses.

    Phenazepam with hangover syndrome

    The drug is used in toxic and narcological practice.It is used to eliminate alcohol withdrawal and its consequences. It is believed that the use of the drug is possible with a hangover syndrome. But you can use it only as directed by a doctor in case of alcohol intoxication or against the background of withdrawal symptoms.

    During the period of abstinence, patients suffer from obsessive fears and increased anxiety, the presence of anxiety and psychopathic conditions.

    Treatment with a tranquilizer is long-term and is carried out in a hospital setting.Phenazepam with a hangover syndrome only exacerbates the symptoms of mental disorders.

    The concentration of alcohol in the blood remains, with which the substance reacts.

    With an abrupt discontinuation of the drug, there is a risk of withdrawal syndrome. It will provoke the development of a new attack of psychoemotional disorder. You will be tempted to drink alcohol again.

    Taking Phenazepam with a hangover leads to the occurrence of “phenazepam sleep”, which proceeds with the development of complications.During sleep, there is a risk of death from suffocation or cardiac arrest.

    Drinking a tranquilizer with a hangover syndrome is strictly prohibited, since:

    • While maintaining ethanol residues in the blood, Phenazepam reacts and enhances the effect on the central nervous system. Particularly dangerous cases are the use of the drug during prolonged binges, with severe intoxication of the body. Then there is the risk of “Phenazepam Sleep”. During prolonged and sound sleep, there is a possibility of cardiac arrest, asthma attacks.It is also possible death when choking with vomit in the supine position.
    • People who regularly drink alcohol have a higher risk of drug dependence than others.
    • The occurrence of fits of rage, inappropriate behavior is possible.
    • There is a decrease in performance, a weakening of muscle activity, lethargy appears.

    Consequences of application

    The use of Phenazepam and alcohol leads to a number of serious complications.Their degree and nature will depend on the volume of alcohol consumed and the dose of the medication taken:

    • Inhibition of consciousness appears, coordination of movement is disturbed. The person is haunted by hallucinations. There is nausea, vomiting.
    • Difficulty breathing begins, shortness of breath with attacks of suffocation.
    • Intoxication of the body occurs. The combination of a tranquilizer with an alcoholic drink leads to destructive processes in the brain.
    • A person is prone to suicide.He is overcome by bouts of unreasonable anger and irritation.
    • There is a possibility that the heart will stop working.
    • In severe cases, a person falls into a coma, which ends in death.

    The body’s reaction to Phenazepam with alcohol depends on individual intolerance: some suffer from shortness of breath, others lose consciousness. For some, a dangerous cocktail is fatal. But the conclusion is unique for everyone: alcohol is incompatible with Phenazepam under any circumstances!

    While drinking alcohol, tranquilizer overdose often occurs.The terrible incompatibility of alcohol with the drug is aggravated by the intoxication of the body from an overdose of pills. There are such symptoms indicating an overdose of a tranquilizer and intoxication of the body:

    • Nausea and vomiting.
    • Pallor and blue discoloration of the skin.
    • There is urinary incontinence and involuntary defecation.
    • Decrease in body temperature.
    • Rapid breathing and heart rate.
    • Light-headedness.

    There are 4 stages of Phenazepam poisoning:

    1. At the first stage of intoxication, symptoms similar to alcohol poisoning appear. A few hours after consumption, a person is in a state of euphoria, speech impairment is observed. Further, there is a violation of the coordination of movements. The euphoric state is replaced by weakness, apathy, drowsiness. The man falls asleep. There is a decrease in pulse rate, the pupils react to light.
    2. The second stage is characterized by a superficial coma.The patient loses consciousness. Retains the ability to respond to external stimuli. Muscle tone is reduced. Vomiting begins.
    3. In the third stage, the injured person is in a deep coma. Does not respond to pain. All reflexes are suspended. There is a malfunction in the liver and kidneys. Urgent medical attention is needed.
    4. The fourth stage occurs after the timely assistance provided by doctors. It is characterized by the restoration of the state of health.

    First aid

    To eliminate the consequences of the use of Phenazepam with alcohol, urgent medical assistance is needed.You can try to alleviate the condition of the victim before the arrival of an ambulance.

    It is necessary to rinse the stomach with water with added salt. It is necessary to repeat the procedure until the wash water becomes transparent. Further, if the victim is conscious, cleanse the intestines with an enema. Give the patient a sorbing agent – activated carbon, Polysorb or Enterosgel.

    It is necessary to monitor a person’s condition before providing medical assistance.It is necessary to monitor breathing and pulse. In case of fainting, lay the victim so as to fix the legs above the level of the head.

    Also, to prevent the effect of tongue sinking, an unconscious patient needs to tilt his head back and open his mouth, pushing the lower jaw forward.

    Under stationary conditions, it is necessary to intravenously inject the antidote of Phenazepam – flumazenil. The drug should be used in a course of 10 injections, which is equal to 3 mg. In severe cases, hemodialysis is performed, tracheal intubation is performed.

    List of standard hospital procedures after taking Phenazepam with alcohol:

    • Using a probe to cleanse the stomach.
    • Droppers with saline and glucose to eliminate intoxication of the body.
    • Use of drugs to normalize the functioning of the respiratory system, stabilize pressure.
    • Use of a ventilator in case of shortness of breath.
    • Resuscitation measures.

    How to avoid the consequences

    It is possible to take alcohol after a tranquilizer only when the medicine is excreted from the body. The instructions say that the elimination time for half the dose of the drug is 12 hours. After this gap, 50 percent of the dose of the drug used will remain in the blood. After the next 12 hours, the second part of the substance will be excreted. This means that the concentration in the blood will be zero.

    However, it is impossible to say with certainty when and in what quantity the drug will be excreted from the blood.Therefore, the optimal period of time is at least 48 hours from the moment of using the last pill. It is strictly forbidden to drink the medicine with alcohol and mix it with alcohol!

    Source: https://GastroTract.ru/intoksikatsiya/fenazepam-i-alkogol.html

    Phenazepam and Alcohol – Can Phenazepam be taken with alcohol?

    Sometimes a person raises a glass without thinking about the course of treatment and the drugs taken the day before. Often, unacceptable lightheadedness turns into death.

    Accidental combination of the tranquilizer phenazepam with any alcoholic beverage can lead to very serious consequences, including death. There is no need to talk about a deliberate “cocktail” of pills and alcohol. The mortality rate among homegrown “alchemists” is incredibly high. A person seems to be testing his own body for strength.

    Can I take phenazepam with alcohol

    Phenazepam belongs to a number of widely prescribed tranquilizers. Prescription restrictions indicate the specificity of the drug.Doctors include it in the treatment of anxiety, depression and other psychosomatic conditions. The drug inhibits brain activity, promotes immersion in sound sleep.

    The tranquilizer has a similar effect to alcohol on the nervous system and the brain. Which makes it very dangerous to take them together.

    The annotation to the drug contains a warning about unwanted alcohol intake during the course of treatment. Also, phenazepam has identical side properties as alcohol.The tablets increase the effect of alcohol on the nervous system and brain activity. A great danger is caused by taking the drug after prolonged binges, when there is still a residual concentration of ethyl alcohol in the body.

    [idea] A hangover is not a sign of sobriety! Frequent drinking takes a longer time to cleanse the body of alcohol. [/ Idea]

    Consequences of a dangerous combination

    Phenazepam multiplies the severity of the “drunken sleep”.As a result, the victim has dangerous symptoms:

    • Intermittent breathing;
    • Attenuation of the heart rate;
    • Vomiting during sleep;
    • Crash syndrome;
    • Amnesia.

    Usually, a person needs to take a very high dose of alcohol in order to fall into a “drunken sleep”. At this stage of intoxication, it is recommended to call an ambulance. Phenazepam lubricates and accelerates the transition to the stages of intoxication. This condition poses a high threat to life.

    The lethal dose is only 10 mg. Which is just a few pills. An overdose can occur from a lower dose, given the mutually reinforcing effect of the drug and ethyl alcohol.

    Alcohol, in turn, increases the side effects of phenazepam, which affect mental health:

    • Depressed state;
    • Confused knowledge;
    • Uncontrolled aggression;
    • Paranoid fear;
    • Disorientation;
    • Weak memory;
    • Suicidal tendencies.

    “Isoprinosine” and alcohol: compatibility, consequences

    Human behavior defies explanation. He becomes unpredictable, dangerous to others. Such a condition requires increased attention from loved ones.

    A dangerous combination of phenazepam and alcohol becomes apparent. It is dangerous to take a tranquilizer with any alcohol, even with whiskey, even with wine or beer.

    It is important that the drink contains ethyl alcohol in any concentration.

    Phenazepam instructions for use with alcohol

    Narcologists prescribe phenazepam in combination with other drugs for the treatment of alcohol withdrawal. A tranquilizer relieves the symptoms of alcohol withdrawal when the body insistently demands another dose of alcohol. A multi-day course of treatment helps to eliminate anxiety, insomnia, mood swings, and depression.

    At the same time, experts observe great caution in the use of phenazepam and cancel it as soon as possible.This is due to the high rate of habituation of the organism, against the background of which phenazepam dependence is already formed. Usually, the course of treatment is no more than ten days. Subsequently, it is replaced with more harmless tranquilizers.

    How long can phenazepam after alcohol

    Instructions for the use of phenazepam states that the half-life is 12 hours. Consequently, after this period of time, half of the dose of the sedative drug taken the day before will remain in the body.After the next 12 hours, another half of the remaining concentration of phenazepam will be excreted. A blood level of 0.2 mg is considered safe for drinking.

    Quite a complicated explanation for a simple consumer and alcoholic drinker. Simply put, each tablet contains 2 mg of phenazepam. After 24 hours, 0.5-1 mg will remain in the body. A day later – 0.125-0.25 mg. It is still too early to drink alcohol even at the end of the second day after taking the last tranquilizer pill. You must wait a full two days so as not to endanger your life.

    Phenazepam and Safe Driving

    The inhibitory property of the drug predetermines the restriction on driving or other activities that require a quick mental and muscular response.