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Aristocort side effects: Side Effects of Aristocort (Triamcinolone Diacetate Injectable Suspension), Warnings, Uses

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Aristocort – Uses, Side Effects, Interactions

How does this medication work? What will it do for me?

Triamcinolone belongs to the class of medications called topical corticosteroids. It is used to treat certain skin conditions, including psoriasis and allergic eczema. It may also be used to relieve itchiness. It works by reducing inflammation or swelling of the skin.

This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.

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What do you do when topical medications aren’t enough?

What form(s) does this medication come in?

Cream
Aristocort “C” (0.5%), concentrate; Aristocort “R” (0.1%), regular. Nonmedicinal ingredients: benzyl alcohol, emulsifying wax, glycerin, isopropyl palmitate, lactic acid, sorbitol solution, and purified water.

Ointment
Aristocort “R” (0.1%), regular. The ointment contains no preservatives. Nonmedicinal ingredients: white petrolatum.

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How should I use this medication?

A small amount of this medication should be applied to the affected areas no more than 3 or 4 times daily. For some cases of psoriasis and certain other conditions, your doctor may advise you to cover the area with an occlusive dressing (a dressing that doesn’t breathe) such as plastic wrap for more effective treatment. If your doctor has not suggested this, do not cover the area as this may cause unwanted effects.

Do not let this medication get in your eyes. If contact occurs, flush with plenty of water and consult your doctor.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is important to use this medication exactly as prescribed by your doctor. If you miss a dose, apply it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Who should NOT take this medication?

Do not use this medication if you:

  • are allergic to triamcinolone or any ingredients of the medication
  • have a skin infection caused by viruses, including herpes simplex, vaccinia, and varicella (chickenpox)
  • have tuberculosis of the skin
  • have untreated infected skin lesions caused by an infection with fungi or bacteria if no antifungal (for fungal infections) or antibacterial agent (for bacterial infections) is used at the same time

What side effects are possible with this medication?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • burning, dryness, irritation, itching, or redness or skin (usually mild and temporary)
  • increased redness or scaling of skin sores (usually mild and temporary)
  • skin rash (usually mild and temporary)

Although most of these side effects listed below don’t happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • blood-containing blisters on skin
  • blood vessels visible through the skin (or “spider veins”)
  • burning and itching of skin
  • lack of healing of skin condition
  • skin discoloration
  • skin infection
  • stretch marks
  • thinning of skin with easy bruising

Additional side effects may occur if this medication is used improperly or for long periods of time. Check with your doctor as soon as possible if any of the following side effects occur:

  • acne or oily skin
  • backache
  • blurring or loss of vision (occurs gradually if used near the eye)
  • burning and itching of skin with pinhead-sized red blisters
  • depression
  • eye pain (if used near the eye)
  • filling or rounding of the face
  • increased blood pressure
  • irregular heartbeat
  • irregular menstrual periods
  • irritability
  • irritation of skin around mouth
  • loss of appetite
  • muscle cramps, pain, or weakness
  • nausea
  • rapid weight gain or loss
  • reddish-purple lines on arms, face, legs, trunk, or groin
  • skin colour changes
  • softening of the skin
  • stomach bloating, burning, cramping, or pain
  • swelling of feet or lower legs
  • tearing of the skin
  • unusual bruising
  • unusual decrease in sexual desire or ability (in men)
  • unusual increase in hair growth, especially on the face
  • unusual loss of hair, especially on the scalp
  • unusual tiredness or weakness
  • vomiting
  • weakness of the arms, legs, or trunk (severe)
  • worsening of infections

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.

Are there any other precautions or warnings for this medication?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Inform all doctors you go to that you are using a topical (skin-applied) corticosteroid.

Absorption: When triamcinolone is used over extensive areas for prolonged periods and under dressings that don’t breathe, it is possible that enough medication will absorb into the bloodstream to give rise to unwanted side effects. Therefore, it is advisable to use triamcinolone for brief periods only and to stop using it as soon as the problem clears.

Adverse effects: Although adverse effects associated with the use of this medication are uncommon and not to be expected from ordinary use, sensitization, irritation, and failure of therapeutic response have been noticed in rare instances.

Eyes: Use this medication with caution on lesions close to the eye. Take care to ensure that it does not enter the eye, as glaucoma may result. Cataracts have been reported following internal use of corticosteroids.

Infection: Topical corticosteroids may increase the risk of developing a skin infection. Contact your doctor if you notice any increased redness, swelling, heat, or pain around the area where the medication is applied as these are possible signs of infection.

Thinning of skin: Using topical corticosteroid medications for a long period of time can cause skin to thin or soften or cause stretch marks. Your doctor may recommend you stop using this medication once in a while or to apply to one area of the body at a time. Suddenly stopping corticosteroid medication may cause psoriasis to return.

Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.

Breast-feeding: It is not known if triamcinolone passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The active ingredient in this medication, triamcinolone, belongs to the family of medications known as corticosteroids. Children may be more likely to experience the side effects encountered by using large amounts of this class of medication for long periods of time (e.g., slowing down of growth, delayed weight gain). The use of this medication by children should be limited to the smallest effective amount. Discuss with your doctor the risks and benefits of using medication by children.

What other drugs could interact with this medication?

There may be an interaction between triamcinolone and any of the following:

  • other topical medications that contain corticosteroids or that have irritating effects

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

All material copyright MediResource Inc. 1996 – 2021. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Aristocort

Aristocort Cream (Triamcinolone) – InhousePharmacy.vu

Product Name
Aristocort Cream 100g/Tube

Active Ingredient
Triamcinolone acetonide 0.02% w/w

Manufacturer
Sigma Pharmaceuticals

Product Type
Corticosteroid (topical anti-inflammatory)

Product expiry date we are currently shipping
Jul 2022

Aristocort Cream 0. 02% contains triamcinolone, a corticosteroid used as a topical treatment for various forms of chronic inflammatory skin disease like eczema and dermatitis, to relieve symptoms like itchy, dry and inflamed skin.

Aristocort Cream general information

What is Aristocort Cream used for?

Aristocort Cream 0.02% is a topical skin cream used to treat several moderate to severe inflammatory skin diseases, such as various forms of dermatitis and eczema, including seborrhoeic dermatitis (a scaly rash that usually affects areas of the skin or scalp that are greasy or oily), neurodermatitis, caused by repeated rubbing or scratching, and other and chronic inflammatory skin conditions like psoriasis that forms patches of red scaly rash. Aristocort Cream 0.02% is also used to treat otitis externa (inflammation of the outer ear and ear canal) and anal and vulval pruritus or itching. Aristocort Cream 0.02% helps relieve symptoms such as itching, redness, dryness, crusting, scaling and discomfort.

How does Aristocort Cream work?

Aristocort Cream 0.02% contains the synthetic corticosteroid triamcinolone, which is a moderately potent glucocorticoid steroid hormone that is more potent than prednisone. Triamcinolone in Aristocort Cream 0.02% has anti-inflammatory, antipruritic (stops itching) and immunosuppressive properties. It also has vasoconstrictor actions, which means that it causes blood vessel narrowing. Triamcinolone in Aristocort Cream 0.02% works by blocking the enzyme involved in the production of a hormone-like substance called prostaglandin, which causes inflammation. Triamcinolone also blocks formation of other mediators of inflammation, like kinins and histamine release which causes itching, and also modifies the body’s immune response. These actions of Aristocort Cream 0.02% reduce symptoms of inflammatory skin conditions.

What does Aristocort Cream contain?

Aristocort Cream 0.02% contains the active ingredient triamcinolone acetonide, a synthetic corticosteroid used as a topical treatment for inflammatory skin conditions. It also contains emulsifying wax, isopropyl palmitate, glycerol, sorbitol, lactic acid, 2% benzyl alcohol and purified water.

Aristocort Cream for inflammatory skin disease

Aristocort Cream 0.02% contains triamcinolone, a corticosteroid that is used as a topical treatment for various forms of chronic inflammatory skin disease. These include eczema and dermatitis, including atopic eczema, an inherited form of eczema, seborrhoeic dermatitis (a scaly rash that usually affects areas of the skin or scalp that are greasy or oily), neurodermatitis, caused by repeated rubbing or scratching, and other and chronic inflammatory skin conditions like psoriasis that forms patches of red scaly rash. Triamcinolone in Aristocort Cream 0.02% has anti-inflammatory properties and inhibits the production of inflammatory mediators like prostaglandins, which helps relieve symptoms such as itching, redness, dryness, crusting, scaling and discomfort.

Aristocort Cream for itchy skin

Aristocort Cream 0. 02% contains triamcinolone, a corticosteroid that is used to help relieve itchy skin, which is a symptom of several skin conditions, like dermatitis, eczema and psoriasis, and can cause the skin to become sore and inflamed. It is also used to treat otitis externa (inflammation of the outer ear and ear canal), anal and vulval pruritus or itching. Triamcinolone in Aristocort Cream 0.02% has anti-inflammatory properties and inhibits the production of inflammatory mediators like prostaglandins, and histamine release, which causes itching. These actions of Aristocort Cream 0.02% reduce symptoms of inflammatory skin conditions that cause itching and other conditions characterised by pruritus or itching.

What are the side effects of Aristocort Cream?

The most commonly reported side effects when using Aristocort Cream 0.02% include: burning, itching, irritation and dryness at the site of application, stretch marks (striae), drying or cracking of the skin caused by atrophy, minor infection if used under a dressing. Long-term use of Aristocort Cream may cause the adrenal glands, which produce endogenous (naturally occurring) corticosteroids, to stop working efficiently and this may slow down the growth rate in children.

When should Aristocort Cream not be used?

You should not use Aristocort Cream if you:

  • are allergic to triamcinolone or any ingredients in Aristocort Cream
  • are pregnant or are breastfeeding without discussion with your doctor
  • have a viral infection of the skin, tuberculosis, acne rosacea (a chronic skin condition), perioral dermatitis (facial rash around the mouth), fungal skin infections or ulcerative conditions
  • have damaged skin

How should Aristocort Cream be used?

You should apply your Aristocort Cream 0.02% to the affected area of skin by gently rubbing a small amount into the skin, 3-4 times daily. You should always wash your hands after applying the medication and make sure you don’t get any in your eyes, nose or mouth. For eczematised psoriasis you should apply your Aristocort Cream 0.02% under an occlusive impermeable dressing. You should continue to use Aristocort Cream 0.02% for as long as recommended by your doctor and depending on your condition; long term continuous use should be avoided as it can cause problems.

How long should you use Aristocort Cream?

You should continue to use Aristocort Cream 0.02% for as long as recommended by your doctor and depending on your condition; long term continuous use should be avoided as it can cause problems.

Missed dose of Aristocort Cream

If you miss a dose of Aristocort Cream 0.02% apply it as soon as you remember, unless it is time for the next dose, then skip the missed dose. Do not take a double dose.

How should Aristocort Cream be stored?

You should store your Aristocort Cream below 25°C in a cool dry place.

Buy Aristocort (Triamcinolone) from Our Certified Canadian Pharmacy

Type

Drug

Mfr.

Country

Dosage

Qty

Price(USD)

Type:

Drug:Aristocort Ointment

Mfr.:Bristol-Myers Squibb

Country:Turkey

Dosage:0.1 %/20 gm

Qty:1

Price:$33.99

Type:

Aristocort Ointment

Bausch Health

Canada

0.1 %/30 gm

1

$22.99

Type:

Drug:Aristocort Cream

Mfr.:Bausch Health

Country:Canada

Dosage:0. 1 %/30 gm

Qty:1

Price:$22.99

Type:

Aristocort Cream

Bausch Health

Canada

0.1 %/30 gm

3

$37.99

Type:

Drug:Aristocort Ointment

Mfr.:Bausch Health

Country:Canada

Dosage:0.1 %/30 gm

Qty:3

Price:$37.99

Type:

Aristocort Cream

Bausch Health

Canada

0.5 %/15 gm

1

$43. 99

Information

Aristocort (Triamcinolone) is a prescription medication that is used to treat a variety of skin conditions such as eczema, dermatitis, allergies and rash. Triamcinolone belongs to the class of drugs called corticosteroids. This medication works by reducing the actions of chemicals in the body that cause inflammation. It reduces the swelling, itching and redness that occur with these types of skin conditions.

Manufacturer Information

Canadian Pharmacy King is currently offering the brand Aristocort ointment from Turkey and Canada manufactured by Bristol-Myers Squibb. We also carry the Aristocort cream from Canada manufactured by Bristol-Myers Squibb. Aristocort ointment is available in the strength of 0.1%/20 gm, 0.1%/30 gm ointment and 0.5%/15 gm cream.

Side Effects

The common side effects of Aristocort may include burning, dryness, irritation and itching when this medication is first applied to the skin.

Inform your doctor right away if you have any of the serious side effects such as:

• Headache;

• Increased thirst or urination;

• Swelling ankles or feet;

• Unusual or extreme tiredness;

• Vision problems;

• Weight loss

This is not a complete list of side effects and others may occur. Please call your doctor if you have any further concerns or questions.

Customer Precautions

You should not use Aristocort if you are allergic to Triamcinolone or if you have any other allergies. Before you start taking this medication, talk to your doctor about your medical history and about all the medications you take including OTC and herbal medications. You should not use this medication if you have an infection or sore present in the area to be treated. Aristocort may slow down a child’s growth if used for a long time. Check your child’s height checked regularly. This medication should not be used during pregnancy unless it is clearly needed. It is unknown whether this medication passes into breast milk when applied to the skin. Talk to your doctor before breast-feeding.

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Aristocort product description


Drug uses

Aristocort is a corticosteroid with mainly glucocorticoid activity. The drug provides an anti-allergic, immunosuppressive, and anti-inflammatory effect. Aristocort inhibits connective tissue reaction during inflammation and reduces scar tissue regeneration. In addition, the drug relieves swelling, itching, and redness.

Immunosuppressant Aristocort can be administered to patients by intramuscular, intradermal, and intra-articular ways. Glucocorticoid Aristocort is effective in treatment of:

  • allergic states
  • endocrine disorders
  • rheumatic disorders
  • hematologic disorders
  • dermatologic diseases
  • gastrointestinal diseases

Duration of Aristocort application depends on the pathology nature and the treatment efficiency. Depending on the specific disease, an initial dosage for adults may vary from 3 mg to 48 mg per day. An initial dose for children may vary from 0.11 to 1.6 mg per kg of the body weight, divided in three doses.

Missed dose

The patient should be aware that the prescribed dosage regimen should be strictly complied during treatment with glucocorticoid Aristocort, and if the dose of Aristocort is accidentally missed, the drug should be taken as soon as possible.

If it is nearly time for the next dose of the immunosuppressant, the missed dose of Aristocort is recommended to skip, and to continue with regular dosing schedule. Do not take 2 doses of Aristocort at once, as it causes overdose and side effects.

More information

Patients are not recommended to abruptly stop taking corticosteroid Aristocort, since it may lead to adrenal insufficiency. Extra caution should be taken by patients with renal insufficiency, hypertension, or osteoporosis while on the drug. During treatment with corticosteroids, the patients are not advised to be vaccinated. Corticosteroids may reduce the resistance to infections and mask the symptoms.

Storage

Aristocort drug should be protected from moisture, sunlight, and freezing and be stored at temperature of 20°C to 25°C, out of the children’s reach.

Aristocort safety information


Warnings

Aristocort should not be indicated to patients with fungal skin infections, cutaneous tuberculosis, viral skin infections (such as shingles, varicella, and cold sores). Corticosteroid Aristocort is not recommended for pregnant women and breastfeeding mothers.

The glucocorticoid drug should be avoided in dysmature infants because it contains benzyl alcohol. It is recommended to be prescribed with extra caution to patients suffering from diverticulitis, nonspecific ulcerative colitis, and peptic ulcer since Aristocort increases the risk of gastrointestinal perforation.

Particular caution is recommended while taking Aristocort for the patients with an increased risk of osteoporosis (for example, in post-menopausal women). Under corticosteroid influence, bone density may decrease, leading to weakened and fragile bones making them more prone to fractures.

Disclaimer
Information about Aristocort is intended to increase awareness of this anti-inflammatory drug, and in any way should not be used as the recommendations provided by the attending physician. The online pharmacy disclaims all damages of any kind (without limitation) arisen from the use of any and all published information about Aristocort.

Aristocort side effects


Aristocort may cause variety of unwanted effects whilst be used, most frequent of them are as follows: headache and exacerbation of infectious diseases. Other common unwanted effects involve the skin, such as dry skin, redness, rash, itching, irritation, skin cracking, and epidermal atrophy.Aristocort corticosteroid is rarely reported to cause arthralgia, arrhythmia, emotional instability, and weight gain. In case of such unwanted effects, as telangiectasia, anaphylaxis, or angioedema, the treatment with Aristocort should be immediately stopped.

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Aristocort product description


Drug uses

Aristocort is a corticosteroid with mainly glucocorticoid activity. The drug provides an anti-allergic, immunosuppressive, and anti-inflammatory effect. Aristocort inhibits connective tissue reaction during inflammation and reduces scar tissue regeneration. In addition, the drug relieves swelling, itching, and redness.

Immunosuppressant Aristocort can be administered to patients by intramuscular, intradermal, and intra-articular ways. Glucocorticoid Aristocort is effective in treatment of:

  • allergic states
  • endocrine disorders
  • rheumatic disorders
  • hematologic disorders
  • dermatologic diseases
  • gastrointestinal diseases

Duration of Aristocort application depends on the pathology nature and the treatment efficiency. Depending on the specific disease, an initial dosage for adults may vary from 3 mg to 48 mg per day. An initial dose for children may vary from 0.11 to 1.6 mg per kg of the body weight, divided in three doses.

Missed dose

The patient should be aware that the prescribed dosage regimen should be strictly complied during treatment with glucocorticoid Aristocort, and if the dose of Aristocort is accidentally missed, the drug should be taken as soon as possible.

If it is nearly time for the next dose of the immunosuppressant, the missed dose of Aristocort is recommended to skip, and to continue with regular dosing schedule. Do not take 2 doses of Aristocort at once, as it causes overdose and side effects.

More information

Patients are not recommended to abruptly stop taking corticosteroid Aristocort, since it may lead to adrenal insufficiency. Extra caution should be taken by patients with renal insufficiency, hypertension, or osteoporosis while on the drug. During treatment with corticosteroids, the patients are not advised to be vaccinated. Corticosteroids may reduce the resistance to infections and mask the symptoms.

Storage

Aristocort drug should be protected from moisture, sunlight, and freezing and be stored at temperature of 20°C to 25°C, out of the children’s reach.

Aristocort safety information


Warnings

Aristocort should not be indicated to patients with fungal skin infections, cutaneous tuberculosis, viral skin infections (such as shingles, varicella, and cold sores). Corticosteroid Aristocort is not recommended for pregnant women and breastfeeding mothers.

The glucocorticoid drug should be avoided in dysmature infants because it contains benzyl alcohol. It is recommended to be prescribed with extra caution to patients suffering from diverticulitis, nonspecific ulcerative colitis, and peptic ulcer since Aristocort increases the risk of gastrointestinal perforation.

Particular caution is recommended while taking Aristocort for the patients with an increased risk of osteoporosis (for example, in post-menopausal women). Under corticosteroid influence, bone density may decrease, leading to weakened and fragile bones making them more prone to fractures.

Disclaimer
Information about Aristocort is intended to increase awareness of this anti-inflammatory drug, and in any way should not be used as the recommendations provided by the attending physician. The online pharmacy disclaims all damages of any kind (without limitation) arisen from the use of any and all published information about Aristocort.

Aristocort side effects


Aristocort may cause variety of unwanted effects whilst be used, most frequent of them are as follows: headache and exacerbation of infectious diseases. Other common unwanted effects involve the skin, such as dry skin, redness, rash, itching, irritation, skin cracking, and epidermal atrophy.Aristocort corticosteroid is rarely reported to cause arthralgia, arrhythmia, emotional instability, and weight gain. In case of such unwanted effects, as telangiectasia, anaphylaxis, or angioedema, the treatment with Aristocort should be immediately stopped.

Aristocort (Generic Triamcinolone Topical) – Prescriptiongiant

Triamcinolone comes in ointment, cream, lotion, and aerosol (spray) in various strengths for use on the skin and as a paste for use in the mouth. It usually is applied two to four times a day. For mouth sores, it is applied at bedtime and, if necessary, two or three times daily, preferably after meals. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use triamcinolone exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor. Do not apply it to other areas of your body or use it to treat other skin conditions unless directed to do so by your doctor.

To use triamcinolone topical, apply the ointment, cream, or lotion sparingly in a thin film and rub it in gently.

To use the lotion or aerosol (spray) on your scalp, part your hair, apply a small amount of the medicine on the affected area, and rub it in gently. Protect the area from washing and rubbing until the lotion or spray dries. You may wash your hair as usual but not right after applying the medicine.

To apply an aerosol, shake well and spray on the affected area holding the container about 3 to 6 inches away. Spray for about 2 seconds to cover an area the size of your hand. Take care not to inhale the vapors. If you are spraying near your face, cover your eyes.

To apply the paste, press a small amount on the mouth sore without rubbing until a thin film develops. You may need to use more paste if the mouth sore is large. If the mouth sore does not begin to heal within 7 days, call your doctor.

Triamcinolone aerosol (spray) may catch fire. Stay away from open fire, flames, and do not smoke while you are applying triamcinolone aerosol, and for a short time afterward.

If you are using triamcinolone topical on your face, keep it out of your eyes.

Do not apply other skin preparations or products on the treated area without talking with your doctor.

If you are using triamcinolone on a child’s diaper area, do not use tight-fitting diapers or plastic pants. Such use may increase side effects.

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Aristocort product description


Drug uses

Aristocort is a corticosteroid with mainly glucocorticoid activity. The drug provides an anti-allergic, immunosuppressive, and anti-inflammatory effect. Aristocort inhibits connective tissue reaction during inflammation and reduces scar tissue regeneration. In addition, the drug relieves swelling, itching, and redness.

Immunosuppressant Aristocort can be administered to patients by intramuscular, intradermal, and intra-articular ways. Glucocorticoid Aristocort is effective in treatment of:

  • allergic states
  • endocrine disorders
  • rheumatic disorders
  • hematologic disorders
  • dermatologic diseases
  • gastrointestinal diseases

Duration of Aristocort application depends on the pathology nature and the treatment efficiency. Depending on the specific disease, an initial dosage for adults may vary from 3 mg to 48 mg per day. An initial dose for children may vary from 0.11 to 1.6 mg per kg of the body weight, divided in three doses.

Missed dose

The patient should be aware that the prescribed dosage regimen should be strictly complied during treatment with glucocorticoid Aristocort, and if the dose of Aristocort is accidentally missed, the drug should be taken as soon as possible.

If it is nearly time for the next dose of the immunosuppressant, the missed dose of Aristocort is recommended to skip, and to continue with regular dosing schedule. Do not take 2 doses of Aristocort at once, as it causes overdose and side effects.

More information

Patients are not recommended to abruptly stop taking corticosteroid Aristocort, since it may lead to adrenal insufficiency. Extra caution should be taken by patients with renal insufficiency, hypertension, or osteoporosis while on the drug. During treatment with corticosteroids, the patients are not advised to be vaccinated. Corticosteroids may reduce the resistance to infections and mask the symptoms.

Storage

Aristocort drug should be protected from moisture, sunlight, and freezing and be stored at temperature of 20°C to 25°C, out of the children’s reach.

Aristocort safety information


Warnings

Aristocort should not be indicated to patients with fungal skin infections, cutaneous tuberculosis, viral skin infections (such as shingles, varicella, and cold sores). Corticosteroid Aristocort is not recommended for pregnant women and breastfeeding mothers.

The glucocorticoid drug should be avoided in dysmature infants because it contains benzyl alcohol. It is recommended to be prescribed with extra caution to patients suffering from diverticulitis, nonspecific ulcerative colitis, and peptic ulcer since Aristocort increases the risk of gastrointestinal perforation.

Particular caution is recommended while taking Aristocort for the patients with an increased risk of osteoporosis (for example, in post-menopausal women). Under corticosteroid influence, bone density may decrease, leading to weakened and fragile bones making them more prone to fractures.

Disclaimer
Information about Aristocort is intended to increase awareness of this anti-inflammatory drug, and in any way should not be used as the recommendations provided by the attending physician. The online pharmacy disclaims all damages of any kind (without limitation) arisen from the use of any and all published information about Aristocort.

Aristocort side effects


Aristocort may cause variety of unwanted effects whilst be used, most frequent of them are as follows: headache and exacerbation of infectious diseases. Other common unwanted effects involve the skin, such as dry skin, redness, rash, itching, irritation, skin cracking, and epidermal atrophy.Aristocort corticosteroid is rarely reported to cause arthralgia, arrhythmia, emotional instability, and weight gain. In case of such unwanted effects, as telangiectasia, anaphylaxis, or angioedema, the treatment with Aristocort should be immediately stopped.

Triamcinolone (Topical): Pediatric Medication | Memorial Sloan Kettering Cancer Center

This document, provided by Lexicomp ® , contains all the information you need to know about the drug, including the indications, route of administration, side effects and when you should contact your healthcare provider.

Trade names: USA

Dermasorb TA [DSC]; Dermazone [DSC]; Kenalog; Oralone; Sila III; SilaLite Pak [DSC]; Trianex; Triderm; Tritocin

Trade names: Canada

Aristocort C; Aristocort R; Oracort; Triaderm

What is this drug used for?

All skin products:

  • Used to treat skin rashes and other skin irritations.

Oral paste:

  • This medication is used to treat irritations in the mouth.

What should I tell my doctor BEFORE my child takes this drug?

All forms of issue:

  • If your child is allergic to this drug, any of its ingredients, other drugs, foods, or substances. Tell your doctor about the allergy and how your child has it.

Oral paste:

  • If your child has a mouth or throat infection.

This list of drugs and diseases that may be adversely associated with this drug is not exhaustive.

Talk to your doctor or pharmacist about all medications your child is taking (prescription and over-the-counter, natural products, and vitamins) and any health concerns.You need to make sure that this drug is safe for your child’s illness and in combination with other drugs he or she is already taking. You should not start, stop, or change the dosage of any drug your child is taking without talking to your doctor.

What do I need to know or do while my child is taking this drug?

All forms of issue:

  • Tell all health care providers for your child that your child is taking this drug.These are your child’s doctors, nurses, pharmacists and dentists.
  • Do not use on a child for longer than prescribed by your child’s healthcare provider.
  • If the patient is a child, use this medication with caution. In children, the risk of some side effects may be higher.
  • In some cases, the drug may affect the growth rate in children and adolescents. They may need to check their growth rate regularly. Consult your doctor.

If your daughter is pregnant or breastfeeding:

  • Consult a doctor if your daughter is pregnant, pregnant, or breastfeeding. The benefits and risks for your daughter and her child will need to be discussed.

All skin products:

  • Consult your child’s healthcare professional before using any other drug or product on your child’s skin.
  • Use caution when applying to large areas of skin.Consult your doctor.
  • Using this drug too often by your child may make the skin disorder worse.

Spray:

  • This preparation is flammable. Do not use near open flames or while smoking.
  • Make sure your child is not breathing vapors.

What side effects should I report to my child’s healthcare provider right away?

WARNING / CAUTION: Although rare, this drug can cause very serious and sometimes deadly side effects in some people.Call your child’s doctor right away or get medical attention if your child has any of the following signs or symptoms that could be associated with a very bad side effect:

All forms of issue:

  • Signs of an allergic reaction, such as rash, hives, itching, reddened and swollen skin with blisters or scaling, possibly associated with fever, wheezing or wheezing, tightness in the chest or throat, difficulty breathing, swallowing or speaking, unusual hoarseness, swelling in the mouth, face, lips, tongue, or throat.
  • Signs of high blood sugar, such as confusion, drowsiness, increased thirst and hunger, increased urination, facial flushing, rapid breathing, and fruity breath.
  • Signs of adrenal dysfunction such as severe nausea and vomiting, severe dizziness or loss of consciousness, muscle weakness, extreme fatigue, mood changes, lack of appetite, or weight loss.
  • Signs of Cushing’s disease such as weight gain in the upper back or abdomen, moon face, severe headache, or slow healing.
  • Irritation at the site of application of the medicinal product.

All skin products:

  • Skin changes (acne, stretch marks, slow healing, hair growth).
  • Skin discoloration.
  • Thinning of the skin.

What are some other side effects of this drug?

Any drug can have side effects. However, many people have little or no side effects.Call your child’s doctor or get medical help if any of these or other side effects bothers your child or does not go away:

  • Burn.
  • Itching.
  • Dry skin.

This list of potential side effects is not exhaustive. If you have any questions about side effects, talk to your child’s doctor. Talk to your child’s doctor about side effects.

You can report side effects to the National Health Office.

What is the best way to give this drug?

Give this drug to your child as directed by the doctor. Read all the information provided to you. Follow all instructions strictly.

All skin products:

  • Not for oral administration. For baby skin only. Avoid getting in your child’s mouth, nose and eyes (possible burns).
  • Keep using this drug as directed by your child’s doctor or other healthcare professional, even if your child’s condition improves.
  • Wash hands before and after use.
  • Wash affected area before use. Make sure the skin is dry well.
  • Apply a thin layer to the affected area and rub lightly.
  • Do not use on the face, armpit or groin unless otherwise directed by a physician.
  • Do not apply any coverings (bandages, dressings) unless otherwise directed by your doctor.
  • Do not wear tight-fitting diapers or plastic panties on a baby being treated in the groin-femoral area (“panty area”). This can cause more drug to enter the body.
  • Do not use to treat diaper dermatitis.
  • Do not apply to cuts, scrapes or damaged skin.

Lotion & Spray:

  • Shake well before use.

Oral paste:

  • Keep using this drug as directed by your child’s doctor or other healthcare professional, even if your child’s condition improves.
  • Wash hands before and after use.
  • Using a cotton swab, apply a thin layer to the affected area.Do not rub.
  • Do not let your child swallow the drug.

What if my child misses a dose of a drug?

  • Take the missed dose as soon as you can.
  • If it is time for your child to take the next dose, do not take the missed dose and then return to your child’s normal schedule.
  • Do not use 2 doses at the same time or an additional dose.

How do I store and / or discard this drug?

All forms of issue:

  • Store at room temperature.Do not freeze.
  • Store all medicines in a safe place. Keep all medicines out of the reach of children and pets.
  • Dispose of unused or expired drugs. Do not empty into toilet or drain unless directed to do so. If you have any questions about the disposal of your medicinal products, consult your pharmacist. Your area may have drug recycling programs.

Spray:

  • Protect from heat or open flame. Do not pierce or burn, even if it appears empty.

General information on medicinal products

  • If your child’s symptoms or health problems do not improve, or if they get worse, see your child’s doctor.
  • Do not share your child’s medicine with others or give anyone’s medicine to your child.
  • Some medicines may have other patient information sheets. If you have questions about this drug, talk with your child’s doctor, nurse, pharmacist, or other healthcare professional.
  • If you think an overdose has occurred, call a Poison Control Center immediately or seek medical attention. Be prepared to tell or show which drug you took, how much and when it happened.

Use of information by consumer and limitation of liability

This information should not be used to make decisions about taking this or any other drug. Only the attending physician has the necessary knowledge and experience to make decisions about which drugs are appropriate for a particular patient. This information does not guarantee that the drug is safe, effective, or approved for the treatment of any disease or specific patient.Here are only brief general information about this drug. It does NOT contain all available information on the possible use of the drug with instructions for use, warnings, precautions, information about interactions, side effects and risks that may be associated with this drug. This information should not be construed as a guide to treatment and does not replace the information provided to you by your healthcare professional. Check with your doctor for complete information on the possible risks and benefits of taking this drug.Use of this information is governed by the Lexicomp End User License Agreement available at https://www.wolterskluwer.com/en/solutions/lexicomp/about/eula.

Copyright

© UpToDate, Inc. and its affiliates and / or licensors, 2021. All rights reserved.

TRIAMCINOLONE ACETONIDE (TRIAMCINOLONE ACETONIDE) DESCRIPTION

GCS. Suppresses the function of leukocytes and tissue macrophages. Limits the migration of leukocytes to the area of ​​inflammation.Violates the ability of macrophages to phagocytosis, as well as the formation of interleukin-1. Promotes the stabilization of lysosomal membranes, thereby reducing the concentration of proteolytic enzymes in the area of ​​inflammation. Reduces capillary permeability due to the release of histamine. Suppresses fibroblast activity and collagen formation.

Inhibits the activity of phospholipase A 2 , which leads to suppression of the synthesis of prostaglandins and leukotrienes. Suppresses the release of COX (mainly COX-2), which also helps to reduce the production of prostaglandins.

Decreases the number of circulating lymphocytes (T and B cells), monocytes, eosinophils and basophils due to their movement from the vascular bed into the lymphoid tissue; inhibits the formation of antibodies.

Suppresses the release of ACTH and β-lipotropin by the pituitary gland, but does not reduce the level of circulating β-endorphin. Inhibits the secretion of TSH and FSH.

When applied directly to the vessels, it has a vasoconstrictor effect.

Has a pronounced dose-dependent effect on the metabolism of carbohydrates, proteins and fats.Stimulates gluconeogenesis, promotes the uptake of amino acids by the liver and kidneys, and increases the activity of gluconeogenesis enzymes. In the liver, it enhances the storage of glycogen, stimulating the activity of glycogen synthetase and the synthesis of glucose from the products of protein metabolism. An increase in blood glucose activates the release of insulin.

Suppresses the uptake of glucose by fat cells, which leads to the activation of lipolysis. However, due to the increase in insulin secretion, lipogenesis is stimulated, which contributes to the accumulation of fat.

Has a catabolic effect in lymphoid and connective tissue, muscles, adipose tissue, skin, bone tissue.

Osteoporosis and Itsenko-Cushing’s syndrome are the main factors limiting long-term GCS therapy. As a result of the catabolic effect, it is possible to suppress growth in children.

In high doses, it can increase the excitability of brain tissue and helps to lower the threshold of convulsive readiness. Stimulates excess production of hydrochloric acid and pepsin in the stomach, which contributes to the development of peptic ulcers.

With systemic use, the therapeutic activity is due to anti-inflammatory, antiallergic, immunosuppressive and antiproliferative effects.

When applied topically and locally, the therapeutic activity of triamcinolone acetonide is due to its anti-inflammatory, antiallergic and antiexudative (due to the vasoconstrictor effect) action.

In terms of the anti-inflammatory activity of triamcinolone, acetonide is 6 times more active than hydrocortisone.Mineralocorticoid activity in triamcinolone acetonide is practically absent.

TRIAMCINOLONE is … What is TRIAMCINOLONE?

Triamcinolone

Active ingredient

›› Triamcinolone * (Triamcinolone *)

Latin name

Triamcinolone

ATC:

›› 9› H02AB08 Triamcinolone 10)

›› D55-D59 Hemolytic anemias
›› D69.3 Idiopathic thrombocytopenic purpura
›› E88.0 Plasma protein metabolic disorders, not elsewhere classified
›› I05-I09 Chronic rheumatic heart disease
›› J45 Asthma
›› J98.8.0 * Bronchospasm
›› K50 Crohn’s disease [regional enteritis]
›› K51 Ulcerative colitis
›› L20 Atopic dermatitis
›› L30.9 Dermatitis, unspecified
›› M00-M25 Artropathies 7 ›› M05 Seropositive rheumatoid arthritis
›› M30-M36 Systemic connective tissue lesions
›› M32 Systemic lupus erythematosus
›› M45 Ankylosing spondylitis
›› N04 Nephrotic syndrome
R …8 Other specified general symptoms and signs

Composition and dosage form

1 tablet (divisible) contains triamcinolone 2 or 4 mg; in a package of 50, 100, 500 and 1000 pcs.

Pharmacological action

Pharmacological action – anti-inflammatory, anti-allergic, immunosuppressive.

Indications

Arthritis (rheumatoid, juvenile chronic), rheumatic heart disease, systemic lupus erythematosus and other collagenoses, nephrotic syndrome, bronchial asthma, medicinal and occupational lung lesions, serum sickness, hypoalbuminemia, allergic and inflammatory dermatoses, hemopathic anemia thrombocytopenic purpura, Crohn’s disease, ulcerative colitis.

Contraindications

Hypersensitivity, systemic fungal diseases, tuberculosis, herpes, other local and systemic infections, exacerbation of gastric ulcer and duodenal ulcer, acute glomerulonephritis, intestinal anastomosis.

Side effects

Hoarseness, dry mouth and throat, facial edema, difficulty breathing, cough, weakness, redness, itching, hypertrichosis, skin atrophy, hyper- or hypopigmentation, acne, osteoporosis, cataracts, peptic ulcer, delay growth in children, including infants and adolescents; changes in indicators of protein, fat and electrolyte metabolism, oral candidiasis.

Dosage and administration

Inside, depending on indications – from 4 to 48 mg / day. Children, if possible, are prescribed in the minimum dose and in short courses.

Shelf life

5 years

Storage conditions

List B. In a place protected from light and moisture, at a temperature not higher than 25 ° C.

* * *

TRIAMCINOLONE (Triamcinolonum). 9 a -Fluoro-16 a-oxyprednisolone. Synonyms: Kenacort, Polcortoron, Adcortyl, Albacort, Aristocort, Berlicort, Delfacort, Delsolone, Flogicort, Fluosterolone, Kenacort, Ledercort, Omcilon, Supercort, Triamcinolone, Triamcort, etc.In terms of chemical structure and action, it is close to dexamethasone. It differs from it by the presence of an hydroxy group (OH) instead of CH3 in position C (13). In some cases, it is better tolerated than other glucocorticosteroid analogues. Assign inside. The daily dose is 0.004 – 0.008 – 0.016 g (4 – 8 – 16 mg) in 2 – 4 doses. If necessary, the dose is increased, and after the onset of the therapeutic effect, it is gradually reduced by 0.002 g per day until the minimum maintenance dose is established, usually 0.001 g (1 mg per day).Release form: tablets of 0.004 g (4 mg) in a package of 50 and 100 pieces; Storage: List B. In the dark place. Under the name> 0.1% ointment and cream are produced for external use for dermatitis.

Dictionary of Medicines.
2005.

DermacinRx Trizapak and Pentamidine Isethionate

  • Generic Name: pentamidine
  • Dosage forms: no
  • Other brands: Nebupent, Pentam 300, Pentam

What is Pentamidine Isethionate?

Alternative for the treatment and prevention of Pneumocystis Jirovets (formerly Pneumocystis) pneumonia (PCP).Orphan drug status by the FDA for the treatment and prevention of PCP in patients at high risk of developing the disease.

Co-trimoxazole is the drug of choice for the treatment of mild, moderate and severe PN in adults, adolescents and children, including those with HIV.

CDC, NIS, and IDSA have recommended IL Pentamidine or a regimen of primaquine in combination with clindamycin as an alternative for the treatment of moderate to severe PN in HIV-infected adults and adolescents who cannot tolerate or have not responded to Co-trimoxazole.Some clinicians prefer the primaquine and clindamycin regimen because it may be more effective and associated with lower toxicity than IV pentamidine. For the treatment of Pneumocystis pneumonia in HIV-infected children who cannot tolerate Co-trimoxazole or do not respond after 5-7 days, Co-trimoxazole, CDC, Niz, Iosi, and AAP recommend Yves Pentamidine; treatment can be incorporated into an appropriate oral regimen (eg, atovaquone) following the initial response obtained with IV pentamidine.

CDC, Niz, Yosi, and AAP recommend Pentamidine given by oral inhalation via a nebulizer (aerosolized pentamidine) as one of the possible alternatives for preventing an initial episode of PCD (primary prevention) and for long-term suppressive or chronic therapy (secondary prevention) of Pneumocystis pneumonia in HIV -infected adults, adolescents and children ≥5 years of age who cannot tolerate drugs (Co-trimoxazole).

African trypanosomiasis

Treatment of early or first stage (hemolymphatic) trypanosomiasis caused by trypanosome brucei gambiense, and (West African trypanosomiasis, gambiense, and sleeping sickness).The drug of choice at the first stage, i.e. b. with a Gambian infection; Suramin (not commercially available in the US, but may be available from the CDC) is also effective in the first stage of the disease, but is an alternative because Pentamidine is better tolerated.

Used to treat early or first stage (hemolymphatic) trypanosomiasis caused by TB. rhodesiense; thus (East African trypanosomiasis, sleeping sickness rhodesiense; thus). Suramin (not commercially available in the US, but may be available from the CDC) is usually the first-stage drug of choice.b. rhodesiense; thus infection; Pentamidine is an alternative, but may be less effective in these infections than in TB. infections with the Gambian.

Do not use for treatment in the second stage (meningoencephalitic) t. B. with the Gambian or the like. Rhodesian form of infection with lesions of the central nervous system with pentamidine poorly penetrates the central nervous system. Eflornithine (with or without nitfurtimox) or melarsoprol (a drug not commercially available in the US but may be available from the CDC) is usually recommended for T.B. with a Gambian infection with damage to the central nervous system; Melarsoprol (not commercially available in the US, but may be available from the CDC) is generally recommended for TB treatment. rhodesiense; thus, an infection with damage to the central nervous system.

T. b. with the Gambian, etc. rhodesiense; thus transmitted to humans through the bite of an infected tsetse fly; transmission through blood or perinatal transmission from mother to child is rare. T. b. when the Gambian is widespread in West and Central Africa; T.b. rhodesiense; thus widespread in Eastern and Southern Africa. Trypanosomiasis has been reported in short stays in endemic areas and in immigrants and people from such areas.

For assistance with diagnosis or treatment of trypanosomiasis in the United States, contact the CDC Parasitic Disease Hotline at 404-718-4745 from 8:00 am to 4:00 pm ET or CDC Emergency Operations Center at 770-488-7100 at non-business hours and weekends and holidays. Contact the CDC Narcotics Service at 404-639-3670 for information on how to obtain antiparasitic drugs not readily available in the US.

Leishmaniasis

Used for the treatment of cutaneous and mucocutaneous leishmaniasis caused by various leishmaniasis spp. When systemic treatment is indicated, pentavalent antimonials (ie, sodium stibogluconate and meglumine antimonate [not commercially available in the US, but may be available from the CDC]) are commonly used; other options include amphotericin B, miltefosine, pentamidine, and ketoconazole. Although pentamidine has been recommended for the treatment of New World cutaneous leishmaniasis caused by L.guyanensis or L. panamensis, with varying efficacy and potential side effects, limit its usefulness for other types of cutaneous leishmaniasis.

Used to treat visceral leishmaniasis (also known as Kala Azar). Pentavalent antimonials (eg sodium stibogluconate or meglumine antimonate [drug not commercially available in the US, but may be available from the CDC]) have historically been considered the first choice for the primary treatment of visceral leishmaniasis, but drug resistance and treatment failures have been problematic some areas (eg India, Nepal).Other options include Amphotericin B, miltefosine, or paromomycin. Pentamidine is generally not recommended due to variable or suboptimal efficacy and potential side effects.

Leishmaniasis is caused by> 15 different types of Leishmanias, which are transmitted to humans by the bite of infected mosquitoes; it can also be transmitted through blood (eg, blood transfusions, needles shared by Eve addicts) and intrauterinely from mother to child. In the Eastern Hemisphere (old world), leishmaniasis occurs most frequently in parts of Asia, the Middle East, Africa, and southern Europe; in the Western Hemisphere (new world), occurs most commonly in Mexico and Central and South America, and reported rarely in Texas and Oklahoma.Leishmaniasis has been reported in short stays in endemic areas and in immigrants and immigrants from such areas; also reported in US military personnel serving or working in endemic areas (eg, Iraq, Afghanistan).

The specific form of leishmaniasis and the severity of the disease depend on the species of leishmania, geographic area of ​​origin, location, mosquito bite, and patient-related factors (eg nutritional and immune status). Treatment (e.g. drug, dosage, duration of treatment) should be individualized according to the region where the disease was acquired, likely by infecting drug susceptibility types reported in the area, origin, form of the disease, and patient factors (e.g., age, pregnancy, immune status ).No single treatment is appropriate for all possible clinical manifestations. Consultation with clinicians experience in the management of leishmaniasis is recommended.

Assistance with diagnosis or treatment of leishmaniasis in the United States, contact the CDC Parasitic Disease Hotline at 404-718-4745 from 8:00 am to 4:00 pm ET or CDC Emergency Operations Center at 770-488-7100 at non-business hours and weekends and holidays. Contact the CDC Narcotics Service at 404-639-3670 for information on how to obtain antiparasitic drugs not readily available in the US.

Babesiosis

Used in some patients for the treatment of babesiosis caused by microti babesiosis; effectiveness not established.

Used in combination with cotrimoxazole to treat infection with B. divergens, but has side effects associated with limited pentamidine use of this regimen.

When antibiotic treatment for babesiosis is indicated, Iosi et al. Recommend a regimen of clindamycin and quinine or a regimen of atovaquone and azithromycin.

90,000 💉 Knee injections for osteoarthritis: what to expect

Review

Osteoarthritis of the knee can affect anyone, but it usually develops in people over the age of 50.It is a progressive condition, which means that it becomes more painful and difficult to move your knee over time.

Your doctor will likely prescribe oral medications and suggest lifestyle modifications before recommending knee injections. Before turning to surgery, weigh the pros and cons of injections.

Read on to learn about the different types of knee injections and how they work, and find tips for taking care of your knees.

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Types

What are the different types of knee injections?

These are the main types of knee injections used in the treatment of osteoarthritis.

Corticosteroids

Corticosteroids are designed to be like cortisol, a hormone that is naturally produced in the body. The main goal is to reduce inflammation.

Although oral corticosteroids are used to treat rheumatoid arthritis, which is a systemic disease, it is not a variant of osteoarthritis.

If you have osteoarthritis in the knee, corticosteroids are most effective when injected directly into the joint.This is a targeted treatment to reduce inflammation, so the bone does not shed on the bones when the knee is moved.

The following drugs are classified as corticosteroids:

  • Methylprednisolone (Medrol)
  • Triamcinolone (Aristocort, Aristospan, Clinacort, Kenalog, Triamcot, Triam-Forte, Triesence)

Hyaluronic acid (viscosupplements)

If you have osteoarthritis, you probably do not have enough hyaluronic acid in your knees. This substance helps coat your cartilage and acts as a lubricant and shock absorber so your knee can move freely.

More information: Viscosupplements: Comparison of your capabilities »

This thick preparation serves to supplement your own hyaluronic acid and prevents bones from scraping together. It can also help reduce inflammation and relieve pain.

The following are types of hyaluronic acid injections:

  • sodium hyaluronate (Euflexxa, Hyalgan, Supartz)
  • high molecular weight hyaluronan (Monovik, Ortovik)
  • hylan GF 20 (Synvisc, Synvisc One)
  • cruciform hyaluronate (Gel-One)

Fluid aspiration (arthrocentesis)

Instead of injecting something into the knee, this procedure is withdrawn from the knee.Removing excess fluid can provide immediate relief from pain and swelling. This is sometimes done before receiving an injection of corticosteroid or hyaluronic acid.

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Procedure

What does the procedure include?

Knee injections can be given at your doctor’s office. The procedure takes only a few minutes.

You will be sitting during the procedure and your doctor will place your knee. In some cases, they will use ultrasound to help guide the needle in a better place.

First, the skin on the knee will be cleansed and treated with a local anesthetic. Your doctor will insert a needle into your joint. You may feel some pressure or mild discomfort. The medicine will then be injected into your joint.

In some cases, a small amount of joint fluid is removed first to make room for medication. To do this, the doctor will use a needle attached to a syringe to enter the knee joint. The liquid is then sucked into the syringe and the needle is removed.

Once the fluid has been removed, the same puncture site can be used to inject the appropriate medication into the joint.

A small bandage will be placed over the injection site and you can return home fairly quickly. Your doctor may advise you not to strain your knees for the next day or so. The knee may feel tender for several days. Ask if there are any driving restrictions.

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Pros and cons

Pros and Cons of Knee Injections for Osteoarthritis

Before weighing the pros and cons, you’ll want to ask your doctor what type of injections they plan to give you.Each type carries its own set of pros and cons.

Pros

  1. Corticosteroid injections can provide immediate relief from pain and inflammation. Relief can last up to 24 weeks.
  2. Hyaluronic acid injections may take longer to provide relief, but the benefits can last anywhere from three to six months.
  3. Side effects from hyaluronic acid may be less severe than side effects from corticosteroid injections.

corticosteroid injections

On the positive side, direct injection can provide immediate relief from pain and inflammation.There is evidence for a short-term improvement of up to two weeks, as well as a longer response lasting up to 24 weeks.

On the other hand, not everyone gets relief from a corticosteroid injection. And this is usually a short term solution. You may not be able to have corticosteroid injections if your knee is severely injured.

Potential side effects include:

  • tumor immediately after injection
  • nerve damage
  • thinning of the adjacent bone

.There is also a limit to how often you can receive a corticosteroid injection in the same joint — usually just once every three or four months. Too many injections can break the cartilage, which is even worse. It can also contribute to the development of high blood pressure, osteoporosis, and skin atrophy.

Potential pros and cons of hyaluronic acid injections

The injection may relieve pain and swelling, but not immediately. Research shows that it takes about five weeks before you feel the full effect of the treatment.The relief can last from three to six months. For some people, hyaluronic acid injections do not help.

Potential side effects include:

  • mild injection site reaction
  • outbreak of arthritis immediately after injection

Hyaluronic acid injections are administered differently depending on the product or drug used, some require one injection, while others require multiple injections given weekly.

Potential pros and cons of liquid aspiration

Removing excess fluid can provide immediate relief from pain and discomfort. Side effects may include bruising, swelling, or infection at the aspiration site.

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Outlook

What’s the prospect?

After knee injections, notify your doctor if you have any signs of infection.

The effectiveness of these treatments varies from person to person. Much depends on how far your arthritis has progressed.Some people respond well, but others don’t get relief.

Your doctor can tell you which injections might be helpful for you. If the injections don’t work, talk to your doctor about other treatment options, which may include stronger pain relievers or surgery.

Learn More: Alternatives to Knee Replacement Surgery »

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Tips

Tips for the care of knees

No matter what treatment you get for osteoarthritis of the knees, you should also take other steps to take care of your knees.Here are some tips to get you started:

  • Try to minimize activities that strain your knees. For example, use an elevator or escalator instead of stairs.
  • Avoid strong impacts such as running or tennis. You can replace them with swimming, cycling, or walking, which are great forms of exercise that are also easy on your knees.
  • Maintain a healthy weight or lose a few pounds as needed. The extra weight strains the knees.
  • Use heat and ice to calm your knees.
  • If your knees interfere with mobility, try wearing a knee brace or using a cane.
  • Consider physical therapy or an individualized exercise program with someone who is knowledgeable about osteoarthritis.

Triamcinolone | Triamcinolone – description of the drug, ⚕️ instructions for use, contraindications, reviews | 🧾 Analogs for Triamcinolone

Analogs:

  • Kenacort
  • Polcortolone
  • Adcortyl
  • Albacort
  • Aristocort
  • Burlikourt
  • Delfacourt
  • Delsolon
  • Flogikort
  • Fluosterolone
  • Ledercourt
  • Omtsilon
  • Supercourt

Triamcinolone – description

Indications for use:

– For oral administration: rheumatism, rheumatoid arthritis, systemic lupus erythematosus and other collagenoses, acute allergic reactions, allergic skin diseases, severe forms of bronchial asthma, erythema multiforme, hemorrhagic diathesis, hemolytic anemia, lymphomas, leukemias.

– For parenteral use: rheumatoid arthritis, connective tissue diseases, systemic lupus erythematosus, dermatoses, pulmonary emphysema and pulmonary fibrosis, lymphosarcoma, lymphogranulomatosis, lymphatic leukemia, nephrotic syndrome, sprue.

– For inhalation use: bronchial asthma in the acute phase. Insufficient effectiveness of bronchodilators and / or stabilizers of mast cell membranes in the treatment of bronchial asthma. Hormone-dependent bronchial asthma (in order to reduce the dose of oral corticosteroids).Allergic rhinitis.

– For external use: eczema, psoriasis, neurodermatitis, various types of dermatitis and other inflammatory and allergic skin diseases of non-microbial etiology (as part of complex therapy).

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Method of application and dosage:

Orally for adults – 4-20 mg per day in 2-3 doses. After improvement of the condition, the daily dose is gradually reduced by 1-2 mg every 2-3 days to the minimum maintenance dose of 1 mg and the complete cancellation of therapy.

V / m at the beginning of treatment – 40 mg 1 time per 4 weeks. Then, depending on the indications and the patient’s response to treatment, 40-80 mg can be administered every 2-4 weeks. If necessary, a single dose can be increased to 100 mg. To avoid subcutaneous atrophy, it is injected deep into the muscle.

When administered intra-articularly, as well as when administered in the area of ​​the lesion, the dose is 10-40 mg. The interval between injections is at least 1 week.

For use in the form of inhalation, the dose depends on the dosage form used and the age of the patient.

Applied externally 1-3 times / day. The duration of treatment is determined individually and is usually 5-10 days.
In case of a persistent course of the disease, the course of treatment can be extended up to 25 days. Application for more than 4 weeks is not recommended.

Contraindications:

– history of acute psychosis

– active form of tuberculosis

– myasthenia gravis

– neoplasms with metastases

– diverticulitis

– gastric ulcer and duodenal ulcer

– arterial hypertension

– arterial hypertension

– history of thrombosis and embolism

– osteoporosis

– diabetes mellitus

– hidden foci of infection

– amyloidosis

– syphilis

– fungal diseases

– viral infectionsincluding caused by Herpes simplex and Varicella zoster)

– amoebic infections, poliomyelitis (excluding bulbar-encephalitis form)

– gonococcal or tuberculous arthritis

– vaccination period

– lymphadenitis after vaccination with BCG

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Pharmacological action:

Glucocorticosteroid. Suppresses the function of leukocytes and tissue macrophages. Limits the migration of leukocytes to the area of ​​inflammation.Violates the ability of macrophages to phagocytosis, as well as the formation of interleukin-1.
Promotes the stabilization of lysosomal membranes, thereby reducing the concentration of proteolytic enzymes in the area of ​​inflammation. Reduces capillary permeability due to the release of histamine. Suppresses fibroblast activity and collagen formation.

Inhibits the activity of phospholipase A2, which leads to suppression of the synthesis of prostaglandins and leukotrienes. Suppresses the release of COX (mainly COX-2), which also helps to reduce the production of prostaglandins.

Decreases the number of circulating lymphocytes (T and B cells), monocytes, eosinophils and basophils due to their movement from the vascular bed into the lymphoid tissue; inhibits the formation of antibodies.

Triamcinolone inhibits the release of ACTH and β-lipotropin by the pituitary gland, but does not reduce the level of circulating endorphin. Inhibits the secretion of TSH and FSH.

When applied directly to the vessels, it has a vasoconstrictor effect.

Triamcinolone has a pronounced dose-dependent effect on the metabolism of carbohydrates, proteins and fats.Stimulates gluconeogenesis, promotes the uptake of amino acids by the liver and kidneys, and increases the activity of gluconeogenesis enzymes. In the liver, triamcinolone enhances the storage of glycogen, stimulating the activity of glycogen synthetase and the synthesis of glucose from the products of protein metabolism. An increase in blood glucose activates the release of insulin.

Triamcinolone inhibits the uptake of glucose by fat cells, which leads to the activation of lipolysis. However, due to the increase in insulin secretion, lipogenesis is stimulated, which contributes to the accumulation of fat.

Has a catabolic effect in lymphoid and connective tissue, muscles, adipose tissue, skin, bone tissue.

Osteoporosis and Itsenko-Cushing’s syndrome are the main factors limiting long-term GCS therapy. As a result of the catabolic effect, it is possible to suppress growth in children.

In high doses, triamcinolone can increase the excitability of brain tissue and helps to lower the seizure threshold. Stimulates excess production of hydrochloric acid and pepsin in the stomach, which contributes to the development of peptic ulcers.

With systemic use, the therapeutic activity of triamcinolone is due to anti-inflammatory, antiallergic, immunosuppressive and antiproliferative effects.

When applied topically and locally, the therapeutic activity of triamcinolone is due to its anti-inflammatory, antiallergic and antiexudative (due to the vasoconstrictor effect) action.

When used by inhalation, it has an anti-inflammatory effect on the bronchial mucosa in patients with bronchial asthma.With constant use, it reduces the number of mast cells, macrophages, T-lymphocytes and eosinophils in the epithelium and submucosal layer of the bronchi, suppresses airway hyperresponsiveness.

In terms of anti-inflammatory activity, triamcinolone is close to hydrocortisone, and triamcinolone acetonide is 6 times more active. Mineralocorticoid activity in triamcinolone and triamcinolone acetonide is practically absent.

Side effects:

– From the endocrine system: redistribution of adipose tissue, menstrual irregularities, increased blood glucose levels, suppression of adrenal function, “moon face”, striae, hirsutism, acne.

– From the side of metabolism: edema, electrolyte imbalance, negative nitrogen balance, growth retardation in children.

– From the digestive system: steroid stomach ulcer, erosive and ulcerative lesions of the gastrointestinal tract, acute pancreatitis.

– From the side of the central nervous system: convulsions, sleep disturbances, mental disorders, headaches and dizziness, weakness.

– From the musculoskeletal system: myopathy, osteoporosis.

– From the side of the cardiovascular system: arterial hypertension.

– From the side of the blood coagulation system: thromboembolism.

– From the side of the organ of vision: visual impairment, posterior subcapsular cataract, increased intraocular pressure or exophthalmos, anaphylactic reactions.

– Reactions due to immunosuppressive action: exacerbation of infectious diseases.

– With intra-articular administration: possible joint pain, irritation at the injection site, depigmentation, sterile abscess, skin atrophy, when administered in doses of more than 40 mg, resorptive side effects are possible.

– For inhalation use: possible headache, sneezing, cough, dryness of the mucous membrane of the mouth or nose, irritation in the nose, hoarseness, rarely – a fungal infection of the nasopharynx caused by Candida albicans.

– For external use: itching, skin irritation, late reactions such as eczema, steroid acne, purpura are possible. With prolonged use of the ointment, the development of secondary infectious lesions and atrophic skin changes is possible.

Drug release form:

Synthetic preparation.The main active ingredient is triamcinolone.
Produce:
10 tablets of 0.004 g – 30 pcs. packaged;
0.1% ointment – in a tube of 15 g;
suspension for injection 40 mg / ml in 1 ml ampoules – 5 ampoules per pack.

This page is for informational purposes only! Description of the drug Triamcinolone should not be used by patients to make an independent decision about their use. The decision on the appointment of the drug and the method of its use is made only by the attending physician as a result of an in-person consultation.


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FLUDROCORTISONE (Fludrocortisone).

Synonyms: Cortinef, Florinef, Alfanonidrone, Cortinef, Florinef, Fludronil, etc.

Chemical name: (11beta) -9-Fluoro-11,17,21-trihydroxypregn-4-ene-3,20-dione (and as 21-acetate)

Pharmacology: Pharmacological action – mineralocorticoid, glucocorticoid.

Increases blood pressure, reabsorption of sodium, water and potassium secretion in the renal tubules. Inhibits the production of ACTH, adrenal function, stimulates gluconeogenesis, protein breakdown (causes a negative nitrogen balance), exhibits immunosuppressive and anti-inflammatory activity; when applied topically, it reduces itching and exudation. It is well absorbed from the gastrointestinal tract. Easily passes histohematogenous barriers. T 1/2 – 18-36 hours. It is excreted in the urine in the form of metabolites. A small part is excreted by the lactating mammary glands.

Application: Primary and secondary adrenal insufficiency, adrenogenital syndrome with severe electrolyte loss; locally in ophthalmic practice: keratitis, allergic diseases and eye injuries.

Contraindications: Hypersensitivity, heart failure, hypertension, hyper- and hypothyroidism, osteoporosis, impaired liver and kidney function, systemic and local mycoses, herpes, chronic infections, diabetes, peptic ulcer disease, diverticulitis, mental disorders, pregnancy and lactation; for topical use – fungal and bacterial lesions of the eyes.

Side effects: Adrenal insufficiency, myasthenia gravis, gastrointestinal erosion, increased glucose levels, hyperkalemia, hypertension, headache, dizziness, euphoria, emotional lability, increased intraocular pressure (inside, topically), cataract formation (topically), menstrual irregularities, slowing down growth in children, edema.

Interaction: Increases the effectiveness (and toxicity) of systemic gluco- and mineralocorticoids, reduces – anabolic steroids (but increases their hepatotoxicity), oral antidiabetic drugs.Increases the likelihood of side effects when prescribing cardiac glycosides, drugs that cause hypokalemia (diuretics, amphotericin B). Against the background of sodium-containing drugs, the risk of developing edema and hypertension, acetylsalicylic acid and other NSAIDs – ulceration of the gastric mucosa increases. Psychotropic drugs and alcohol stimulate elimination.

Overdose: Symptoms: arrhythmia, hypokalemia, hypertensive crisis, edema, weight gain.