What are the potential side effects of B12 sublingual tablets. How does cyanocobalamin affect the body. Is vitamin B12 supplementation safe for everyone. What precautions should be taken when using B12 supplements.

The Importance of Vitamin B12 and Its Forms

Vitamin B12, also known as cobalamin, is a crucial nutrient that plays a vital role in various bodily functions. It’s essential for DNA synthesis, red blood cell formation, and proper neurological function. While most people obtain sufficient B12 through their diet, some individuals may require supplementation.

Cyanocobalamin is a synthetic form of vitamin B12 commonly used in supplements, including sublingual tablets. These tablets are designed to dissolve under the tongue, potentially improving absorption compared to traditional oral supplements.

Why might someone need B12 supplements?

• Vegetarian or vegan diets
• Age-related decreased absorption
• Certain medical conditions (e.g., pernicious anemia)
• Medications that interfere with B12 absorption

Understanding B12 Sublingual Side Effects

While vitamin B12 is generally considered safe, some individuals may experience side effects, particularly when taking high doses or using sublingual forms. It’s important to note that many people tolerate B12 supplements well, and severe side effects are rare.

Common side effects of B12 sublingual tablets

• Mild diarrhea
• Itching or mild skin rash
• Headache
• Dizziness
• Nausea
• Vomiting (less common)

Do these side effects occur in everyone? No, most people taking B12 supplements experience no adverse effects. However, it’s essential to be aware of potential reactions and consult a healthcare provider if you have concerns.

Rare but Serious Side Effects of B12 Supplementation

While uncommon, some individuals may experience more severe side effects from B12 supplementation, particularly when using injectable forms or very high doses.

Rare side effects to be aware of

• Pulmonary edema
• Congestive heart failure (early in treatment)
• Vein thrombosis
• Sensation of swelling
• Polycythemia vera (a rare, slow-growing blood cancer)

Is there a risk of allergic reactions to B12 supplements? Yes, although extremely rare, some individuals may experience severe allergic reactions (anaphylaxis) to vitamin B12 supplements. Symptoms can include swelling of the face, tongue, and throat, as well as difficulty swallowing and breathing. If you experience these symptoms, seek emergency medical attention immediately.

Interactions Between B12 and Other Medications

Certain medications can interfere with the absorption or effectiveness of vitamin B12. Understanding these interactions is crucial for individuals taking B12 supplements or those considering supplementation.

Medications that may affect B12 absorption

1. Colchicine
2. Metformin
3. Proton pump inhibitors
4. Vitamin C supplements
5. Chloramphenicol
6. H3 blockers
7. Aminosalicylic acid

How can you ensure proper B12 absorption when taking these medications? If you’re taking any of the above medications, consult your healthcare provider about the optimal timing for B12 supplementation. In some cases, separating the doses (e.g., taking B12 in the morning and the other medication at night) may help maximize absorption.

Recommended Dietary Allowances (RDAs) for Vitamin B12

Understanding the appropriate dosage of vitamin B12 is essential for maintaining optimal health and avoiding potential side effects associated with excessive intake.

RDAs for different age groups and conditions

• Ages 14 years or older: 2.4 micrograms (mcg) daily
• Pregnant women: 2.6 mcg daily
• Breastfeeding women: 2.8 mcg daily

Should older adults take higher doses of B12? For individuals over 50 years of age, it’s recommended to aim for the RDA through a combination of B12-rich foods and supplements containing 25 to 100 mcg of B12, as absorption may decrease with age.

Natural Sources of Vitamin B12

While supplements can be beneficial for some individuals, obtaining vitamins through dietary sources is often preferable. Vitamin B12 is naturally found in various animal-based foods.

Foods rich in vitamin B12

• Eggs
• Cheese
• Fish
• Shellfish
• Liver
• Kidney
• Red meat

Can vegetarians and vegans obtain sufficient B12 from their diet? It can be challenging for vegetarians and especially vegans to get adequate B12 from food sources alone. Fortified foods and supplements may be necessary to meet their nutritional needs.

Managing and Preventing B12 Sublingual Side Effects

If you experience side effects from B12 sublingual tablets or other forms of supplementation, there are steps you can take to address these issues and ensure you’re getting the right amount of this essential vitamin.

Steps to take if you experience side effects

1. Discontinue use of the supplement
2. Consult your healthcare provider
3. Discuss alternative dosages or forms of B12
4. Consider obtaining B12 from dietary sources
5. Monitor symptoms and report any changes to your doctor

How quickly do B12 side effects subside after stopping supplementation? In most cases, side effects should resolve shortly after discontinuing the supplement. However, if symptoms persist or worsen, it’s crucial to seek medical attention.

Special Considerations for B12 Supplementation

While vitamin B12 is generally safe for most people, there are certain groups who should exercise caution or consult a healthcare provider before starting supplementation.

Groups that may require special consideration

• Pregnant and breastfeeding women
• Individuals with a history of allergies or sensitivities
• People with certain medical conditions (e.g., Leber’s disease)
• Those taking medications that interact with B12

Is B12 supplementation safe during pregnancy and breastfeeding? Generally, B12 is considered safe during pregnancy and breastfeeding when taken in recommended dosages. However, it’s always best to consult with a healthcare provider before starting any new supplement regimen during these periods.

Understanding the potential side effects of B12 sublingual tablets and other forms of supplementation is crucial for making informed decisions about your health. While most people tolerate B12 supplements well, being aware of possible adverse reactions and knowing how to manage them can help ensure safe and effective use of this essential vitamin. Always consult with a healthcare professional before starting any new supplement regimen, especially if you have pre-existing medical conditions or are taking other medications.

Vitamin B-12 Side Effects

Vitamin B-12 Side Effects

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Medically reviewed by Jared Meacham, Ph. D., RD, PMP, MBA, CSCS — By Emily Cronkleton — Updated on June 8, 2023

Your doctor will give you the right dosage of vitamin B-12 supplement, especially if you will inject it. Taking too much can cause side effects like nausea, headache, dizziness, and in rarely, blood clots or cancer.

Everyone needs vitamin B-12, and most people get enough through their diet. However, it’s important to know what side effects occur when you take too much.

Vitamin B-12 is water-soluble and absorbed in the intestines. After it’s absorbed, it’s used to make DNA and red blood cells. Vitamin B-12 that isn’t being used is stored in the liver. But if you take supplements, you might ingest more than your body needs.

Oral vitamin B-12 is safe to take at recommended doses for healthy people.

Injectable vitamin B-12, which is used to treat significant deficiencies, can cause the following side effects:

• mild diarrhea
• itching
• skin rash
• headache
• dizziness
• nausea
• vomiting
• pulmonary edema and congestive heart failure early in treatment
• vein thrombosis
• sensation of swelling
• polycythemia vera (rare, slow growing blood cancer)

Vitamin B-12 can cause very rare but serious allergic reactions (anaphylaxis). This includes swelling of the face, tongue, and throat, and difficulty swallowing and breathing. If this occurs after you take vitamin B-12, call 911 or your local emergency services immediately.

Some agents are linked to reduced absorption or serum levels of vitamin B-12. You may need vitamin B-12 supplements if you take any of the following:

• colchicine
• metformin
• proton pump inhibitors
• vitamin C
• chloramphenicol
• h3 blockers
• aminosalicylic acid

Folic acid supplements may interfere with vitamin B-12. Be sure to tell your doctor if you take folic acid.

You may need to take vitamin B-12 separately from the above drugs and supplements — say, one in the morning and one at night — so you can get the full dose of vitamin B-12.

Don’t take vitamin B-12 supplements if you have sensitivities or allergies to vitamin B-12, cobalt, and any other ingredients. Vitamin B-12 is safe to take in recommended dosages if you’re pregnant or breastfeeding.

If you notice any adverse effects after you start taking vitamin B-12 supplements, you should discontinue use immediately. Seek medical attention if your symptoms get worse or are severe.

You can consult your doctor to establish an appropriate dose if it’s determined that you don’t get enough B-12 from food sources.

According to the National Institutes of Health, the recommended dietary amounts (RDAs) are as follows:

• 2.4 micrograms (mcg) daily for ages 14 years or older
• 2.6 mcg daily for pregnant women
• 2.8 mcg daily for breastfeeding women

If you’re over the age of 50, you should try to get your RDA by eating foods with B-12 or by taking a supplement containing 25 to 100 mcg of B-12.

Foods with vitamin B-12 include:

• eggs
• cheese
• fish
• shellfish
• liver
• kidney
• red meat

See your doctor if you have bothersome side effects that don’t go away once you stop taking the supplements. Avoid taking supplements if possible, and try to get B-12 from food sources.

If you develop any side effects from taking vitamin B-12, you can stop taking the supplement and the symptoms should subside.

After this, you’ll need to determine either an appropriate dose or how to get the vitamin B-12 you need from food sources. You can discuss this with your doctor.

Article resources

• Cyanocobalamin – cyanocobalamin injection. (2023). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a66eb3c4-3e1d-4d49-b963-4fa2334cc9b6
• Vitamin B12: Fact sheet for health professionals. (2022). https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/

Last medically reviewed on June 8, 2023

How we reviewed this article:

Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available.

Current Version

Jun 8, 2023

Written By

Emily Cronkleton

Edited By

John Bassham

Medically Reviewed By

Jared Meacham, Ph. D., RD, PMP, MBA, CSCS

Copy Edited By

Copy Editors

Feb 15, 2023

Written By

Emily Cronkleton

Edited By

Frank Crooks

VIEW ALL HISTORY

Share this article

Medically reviewed by Jared Meacham, Ph.D., RD, PMP, MBA, CSCS — By Emily Cronkleton — Updated on June 8, 2023

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Vitamin B-12 Side Effects

Vitamin B-12 Side Effects

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    • No More Silence
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• Plan
  • Health Challenges
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    • Sugar Savvy
    • Move Your Body
    • Gut Health
    • Mood Foods
    • Align Your Spine
  • Find Care
    • Primary Care
    • Mental Health
    • OB-GYN
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    • Psoriasis

Medically reviewed by Jared Meacham, Ph. D., RD, PMP, MBA, CSCS — By Emily Cronkleton — Updated on June 8, 2023

Your doctor will give you the right dosage of vitamin B-12 supplement, especially if you will inject it. Taking too much can cause side effects like nausea, headache, dizziness, and in rarely, blood clots or cancer.

Everyone needs vitamin B-12, and most people get enough through their diet. However, it’s important to know what side effects occur when you take too much.

Vitamin B-12 is water-soluble and absorbed in the intestines. After it’s absorbed, it’s used to make DNA and red blood cells. Vitamin B-12 that isn’t being used is stored in the liver. But if you take supplements, you might ingest more than your body needs.

Oral vitamin B-12 is safe to take at recommended doses for healthy people.

Injectable vitamin B-12, which is used to treat significant deficiencies, can cause the following side effects:

• mild diarrhea
• itching
• skin rash
• headache
• dizziness
• nausea
• vomiting
• pulmonary edema and congestive heart failure early in treatment
• vein thrombosis
• sensation of swelling
• polycythemia vera (rare, slow growing blood cancer)

Vitamin B-12 can cause very rare but serious allergic reactions (anaphylaxis). This includes swelling of the face, tongue, and throat, and difficulty swallowing and breathing. If this occurs after you take vitamin B-12, call 911 or your local emergency services immediately.

Some agents are linked to reduced absorption or serum levels of vitamin B-12. You may need vitamin B-12 supplements if you take any of the following:

• colchicine
• metformin
• proton pump inhibitors
• vitamin C
• chloramphenicol
• h3 blockers
• aminosalicylic acid

Folic acid supplements may interfere with vitamin B-12. Be sure to tell your doctor if you take folic acid.

You may need to take vitamin B-12 separately from the above drugs and supplements — say, one in the morning and one at night — so you can get the full dose of vitamin B-12.

Don’t take vitamin B-12 supplements if you have sensitivities or allergies to vitamin B-12, cobalt, and any other ingredients. Vitamin B-12 is safe to take in recommended dosages if you’re pregnant or breastfeeding.

If you notice any adverse effects after you start taking vitamin B-12 supplements, you should discontinue use immediately. Seek medical attention if your symptoms get worse or are severe.

You can consult your doctor to establish an appropriate dose if it’s determined that you don’t get enough B-12 from food sources.

According to the National Institutes of Health, the recommended dietary amounts (RDAs) are as follows:

• 2.4 micrograms (mcg) daily for ages 14 years or older
• 2.6 mcg daily for pregnant women
• 2.8 mcg daily for breastfeeding women

If you’re over the age of 50, you should try to get your RDA by eating foods with B-12 or by taking a supplement containing 25 to 100 mcg of B-12.

Foods with vitamin B-12 include:

• eggs
• cheese
• fish
• shellfish
• liver
• kidney
• red meat

See your doctor if you have bothersome side effects that don’t go away once you stop taking the supplements. Avoid taking supplements if possible, and try to get B-12 from food sources.

If you develop any side effects from taking vitamin B-12, you can stop taking the supplement and the symptoms should subside.

After this, you’ll need to determine either an appropriate dose or how to get the vitamin B-12 you need from food sources. You can discuss this with your doctor.

Article resources

• Cyanocobalamin – cyanocobalamin injection. (2023). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a66eb3c4-3e1d-4d49-b963-4fa2334cc9b6
• Vitamin B12: Fact sheet for health professionals. (2022). https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/

Last medically reviewed on June 8, 2023

How we reviewed this article:

Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available.

Current Version

Jun 8, 2023

Written By

Emily Cronkleton

Edited By

John Bassham

Medically Reviewed By

Jared Meacham, Ph. D., RD, PMP, MBA, CSCS

Copy Edited By

Copy Editors

Feb 15, 2023

Written By

Emily Cronkleton

Edited By

Frank Crooks

VIEW ALL HISTORY

Share this article

Medically reviewed by Jared Meacham, Ph.D., RD, PMP, MBA, CSCS — By Emily Cronkleton — Updated on June 8, 2023

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• Vitamin B12 Deficiency and Weight Gain — What to Know

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• What Is a Vitamin B-12 Test?

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  A vitamin B-12 test measures the amount of B-12 in your blood. Find out what your B-12 results mean and how to optimize your B-12 intake.

  READ MORE

• Vitamin B12 (folate deficiency anemia) Signs and Symptoms

  By Jillian Kubala, MS, RD

  Vitamin B12 is an important water-soluble vitamin that many people are deficient in. Here are nine signs and symptoms of vitamin B12 deficiency.

  READ MORE

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  By Melissa Groves

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  READ MORE

• What Is Choline? An Essential Nutrient With Many Benefits

  By Mary Jane Brown, PhD, RD (UK)

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  READ MORE

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  READ MORE

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  By Rachael Ajmera, MS, RD

  The mineral magnesium plays a key role in nearly every aspect of your health, and many people take supplements to increase their intake. This article…

  READ MORE

• 7 Emerging Benefits of Pueraria mirifica

  By Ansley Hill, RD, LD

  Pueraria mirifica — or Kwao Krua — has long been used as a rejuvenation therapy in traditional Thai medicine practices. Here are 7 emerging health…

  READ MORE

• 9 Health Benefits of Lion’s Mane Mushroom (Plus Side Effects)

  By Erica Julson, MS, RDN, CLT

  Lion’s mane mushrooms and their extracts contain bioactive substances that have beneficial effects on the body.

  READ MORE

Vitamin B12 (methylcobalamin) spray with free home delivery from VkusVill

VkusVill

VITAMIN B12 Metabolically active form Sublingual spray 3 mcg in 2 sprays = 100% of the norm How to use: take 2 injections in the oral cavity under the tongue 1 once a day. Shake the bottle before use. • 100% of the daily requirement for adults in 2 sprays • 250 sprays: enough for 125 days of use • Convenient spray form: no need to drink, does not contain the extra components inherent in capsules and tablets • Grape flavor, no added sugar The role of vitamin B12 • Vitamin B12 is essential for the production of red blood cells, DNA synthesis, the proper functioning of the nervous system and metabolism • Insufficient intake of vitamin B12 can cause anemia, accompanied by weakness and fatigue • Vitamin B12 is found only in animal products If your diet does not contain animal products, it is important to get vitamin B12 with supplements or fortified foods The body’s ability to absorb vitamin B12 from food decreases with age, so people over 50 may need additional sources of this vitamin

Vitamin B12 (methylcobalamin) spray / Zdorovye

Zdorovye//Vitamins, dietary supplement

VkusVill

573 rub/piece 573. 00 573.00

Description

VITAMIN B12
Metabolically active form
Sublingual spray
3 mcg in 2 sprays = 100% of the norm
How to use: take 2 sprays in the mouth under the tongue 1 time per day. Shake the bottle before use.
• 100% of the daily requirement for adults in 2 sprays
• 250 sprays: enough for 125 days of use
• Convenient spray form: no need to drink, does not contain the extra components of capsules and tablets
• Grape flavor, no added sugar
The role of vitamin B12
• Vitamin B12 is essential for the production of red blood cells, DNA synthesis, proper functioning of the nervous system and metabolism
• Insufficient intake of vitamin B12 can cause anemia, accompanied by weakness and fatigue
• Vitamin B12 is found only in animal products
If your diet does not contain animal products, it is important to get vitamin B12 from supplements or fortified foods
The body’s ability to absorb vitamin B12 from food decreases with age, so people over 50 may need additional sources of this vitamin

When the doctor prescribed B12 in the form of a spray, I was already going to buy it on a foreign site, but I decided, let me look at Vkusvill. It is used very sparingly – 2 puffs a day, the taste is pleasant. Thank you VkusVill for such a gift. Everything you need is at hand and of such excellent quality!

Expiration date

12 months

Nutritional and energy value in 100 g

carbohydrates 0.1 g; 0.4 kcal

Weight/volume

30 ml

Composition

drinking water, stevia leaf extract, vitamin B12 (methylcobalamin), natural wild berry flavor, acidity regulator – citric acid, preservative – sorbic acid.

Label information may vary slightly This product is supplied by several manufacturers, appearance and specifications may vary slightly. The actual data is indicated on the label. The price may differ depending on the region or the format of the point of sale (vending, micromarket).

Show availability in stores

Vitamin B12 health benefits and supplement instructions

There can be many reasons why people start taking vitamin B12, including various diseases, or an examination and tests were carried out, during which a person was found to be deficient in this vitamin.

Or those who do not consume animal products, ie meat, fish, eggs, milk, often need vitamin B12.

If you decide to supplement with B12 or your doctor has prescribed it, then vitamin-mineral complexes will not work in this case.

For example, Optimum Nutrition Opti-men contains B12 in the form of cyanocobalamin, 100 mcg, 4000% DV. This vitamin and mineral complex will not suit you. Firstly, the dosage should be higher, from 1000 mcg, and, secondly, you should remember about the compatibility of vitamins – B12 is needed in its pure form (methylcobalamin).

Also in the composition of such a supplement may be folic acid, which is perfectly combined with methylcobalamin, without interfering with each other’s absorption.

If you are taking B-complex vitamins such as SOLGAR B-Complex 100, Puritan’s Pride B-Complex and B-12, Doctor’s Best Fully B Complex, you don’t have to stop taking them, just take a break between doses. For example, during breakfast, a vitamin-mineral complex, and after 4-5 hours, vitamin B12.

B12 tablets are available as cyanocobalamin and methylcobalamin. This is very easy to check, the manufacturer, as a rule, always indicate this on the back of the package in the composition table.

What is the difference between cyanocobalamin and methylcobalamin?

The latter is the active form of B12 and has a higher bioavailability. However, it is worth noting that the cost may be slightly higher. Although cyanocobalamin is cheaper, its bioavailability is lower, so it is preferable to buy vitamin B12 methylcobalamin.

What is the best way to take vitamin B12?

There is a wide selection of B12 on the market in various forms of release: spray, chewable tablets, liquid, lozenges, regular tablets, capsules. At the same time, it is worth saying that B12 in the form of a spray, chewable tablets and lozenges will be absorbed best.

Which brand is better (B12)?

Now the market is oversaturated with hundreds of manufacturers of vitamins and other supplements. We recommend trusting only trusted brands that have been around for many years and have a good reputation. For example: SWANSON, SOLGAR, NOW FOODS and many others, which are also presented in our store.

How to take vitamin B12?

There is no definite course for taking B12, it is taken based on the need. Vegetarians or those who, for some reason, do not consume enough animal protein, can follow the course on an ongoing basis, because B12 is not toxic, it is a water-soluble vitamin and is quickly excreted from the body. Therefore, it is extremely difficult to achieve an overdose.

Single dosage should be between 1000-1500 µg. It is advisable to take in the morning after a low-fat meal. It is also worth remembering that taking B12 cannot be combined with taking supplements (the exception is folic acid), especially Omega-3 and other fatty acids.

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Methylcobalamin (Vitamin B12), Solgar, 1000 mcg.

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Vitamin B12, Vitamin B12, Solgar, 1000 mcg, 30 Tablets

Methylcobalamin (Vitamin B12), Solgar, 5000 mcg.

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Vitamin B12, Methylcobalamin Vitamin B12, Solgar, 5000 mcg, 30 Tablets…

Vitamin B12, Solgar, 100 mg, 100 Tablets

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Vitamin B12, (Vitamin B12), Solgar, 100 mg, 100 Tablets

Vitamin B12, Solgar, 500 mcg, 100 tabs

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Vitamin B12, Vitamin B12, Solgar, 500 mcg, 100 tabs

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Vitamin B12 sublingual, Solgar, 1000 mcg.

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Vitamin B12 Sublingual, Vitamin B12 1000 mcg Sublingual, Solgar, 1000 mcg, 1…

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Vitamin B12 (Methylcobalamin), Swanson, 5000 mcg, Strawberry Flavor, 60 Tablets

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Vitamin B12 (methylcobalamin), Ultra Vitamin B-12 Methylcobalamin, Swanson, 5000 .