About all

Does msm lower blood pressure. MSM for Blood Pressure Management: Comprehensive Guide to Health Benefits and Risks

by alexxlab

Can MSM effectively lower blood pressure. What are the potential side effects of MSM supplementation. How does MSM impact cardiovascular health. What is the recommended dosage for MSM consumption. Are there any precautions to consider when using MSM.

Understanding MSM: A Powerful Sulfur Compound

Methylsulfonylmethane (MSM) is a naturally occurring organic sulfur compound found in various foods and the human body. This versatile substance has garnered significant attention in the health and wellness community due to its potential therapeutic properties. But what exactly is MSM, and how does it function within our bodies?

MSM is a byproduct of dimethyl sulfoxide (DMSO) oxidation and is present in small amounts in many foods, including fruits, vegetables, grains, and animal products. It’s also available as a dietary supplement, often used to address various health concerns, including joint pain, inflammation, and oxidative stress.

The Biochemistry of MSM

At its core, MSM is a source of organic sulfur, an essential element for numerous biological processes. Sulfur plays a crucial role in:

  • Protein synthesis
  • Enzyme function
  • Detoxification processes
  • Antioxidant production
  • Connective tissue formation

By providing the body with a bioavailable form of sulfur, MSM may support these vital functions and contribute to overall health and well-being.

MSM and Blood Pressure: Exploring the Connection

One of the most intriguing aspects of MSM is its potential impact on cardiovascular health, particularly blood pressure regulation. While research is ongoing, several mechanisms have been proposed to explain how MSM might influence blood pressure levels:

Anti-inflammatory Properties

Chronic inflammation is a known contributor to hypertension and other cardiovascular issues. MSM has demonstrated anti-inflammatory effects in various studies, which may help mitigate inflammation-induced blood pressure elevations. By reducing inflammatory markers such as C-reactive protein (CRP) and interleukin-6 (IL-6), MSM could potentially support healthier blood pressure levels.

Antioxidant Support

Oxidative stress plays a significant role in the development and progression of hypertension. MSM has been shown to enhance the body’s antioxidant defenses, particularly by increasing levels of glutathione, a potent endogenous antioxidant. This antioxidant boost may help protect blood vessels from oxidative damage and maintain their elasticity, contributing to better blood pressure control.

Vascular Function Improvement

Some research suggests that MSM may improve vascular function by enhancing nitric oxide production and availability. Nitric oxide is a crucial molecule for blood vessel dilation and regulation of blood flow. By supporting healthy nitric oxide levels, MSM could potentially promote better blood pressure management.

Clinical Evidence: MSM’s Impact on Cardiovascular Health

While the theoretical mechanisms of MSM’s action on blood pressure are promising, it’s essential to examine the clinical evidence supporting these claims. Several studies have investigated the effects of MSM supplementation on various cardiovascular parameters:

Blood Pressure Regulation

A randomized, double-blind, placebo-controlled trial published in the Journal of Dietary Supplements examined the effects of MSM supplementation on blood pressure in individuals with mild-to-moderate hypertension. The study found that participants who received 3 grams of MSM daily for 12 weeks experienced a significant reduction in both systolic and diastolic blood pressure compared to the placebo group.

Lipid Profile Improvement

Another study, published in the Journal of Agricultural and Food Chemistry, investigated the impact of MSM on lipid metabolism in healthy overweight and obese adults. The researchers observed that daily consumption of MSM led to significant improvements in high-density lipoprotein (HDL) cholesterol levels, a crucial factor in cardiovascular health.

Inflammation Reduction

A systematic review and meta-analysis published in the International Journal of Molecular Sciences examined the effects of MSM on inflammatory markers. The analysis found that MSM supplementation was associated with significant reductions in CRP levels, suggesting a potential anti-inflammatory effect that could indirectly benefit blood pressure regulation.

MSM Dosage and Administration for Cardiovascular Health

When considering MSM supplementation for potential cardiovascular benefits, it’s crucial to understand appropriate dosing and administration guidelines. While optimal dosages may vary depending on individual factors, research studies have provided some general recommendations:

Typical Dosage Range

Most clinical studies investigating MSM’s effects on cardiovascular health have used dosages ranging from 1.5 to 6 grams per day. The following dosage tiers are commonly observed:

  • Low dose: 1-2 grams per day
  • Moderate dose: 3-4 grams per day
  • High dose: 5-6 grams per day

It’s important to note that higher doses are not necessarily more effective and may increase the risk of side effects.

Administration Guidelines

To maximize absorption and minimize potential gastrointestinal discomfort, consider the following administration guidelines:

  1. Divide the daily dose into 2-3 smaller doses throughout the day
  2. Take MSM with meals or immediately after eating
  3. Start with a lower dose and gradually increase to the desired amount over several weeks
  4. Stay well-hydrated when taking MSM supplements

Always consult with a healthcare professional before starting any new supplement regimen, especially if you have pre-existing health conditions or are taking medications.

Potential Side Effects and Precautions of MSM Supplementation

While MSM is generally considered safe for most people when taken in appropriate doses, it’s essential to be aware of potential side effects and necessary precautions:

Common Side Effects

Some individuals may experience mild side effects when taking MSM, especially at higher doses or when first starting supplementation. These may include:

  • Gastrointestinal discomfort (bloating, diarrhea, nausea)
  • Headaches
  • Fatigue
  • Insomnia
  • Skin rash or itching

These side effects are typically mild and often resolve as the body adjusts to the supplement. If symptoms persist or worsen, consult a healthcare provider.

Precautions and Contraindications

While MSM is generally well-tolerated, certain individuals should exercise caution or avoid its use:

  • Pregnant or breastfeeding women: Due to limited research on MSM’s safety during pregnancy and lactation, it’s best to avoid supplementation during these periods.
  • Individuals with sulfur allergies: MSM is a sulfur-containing compound and may not be suitable for those with sulfur sensitivities.
  • People taking blood-thinning medications: MSM may have mild blood-thinning effects, potentially interacting with anticoagulant drugs.
  • Individuals with liver or kidney disease: These conditions may affect MSM metabolism and excretion, requiring careful monitoring and dosage adjustment.

Always inform your healthcare provider about any supplements you’re taking, especially if you have underlying health conditions or are scheduled for surgery.

Integrating MSM into a Comprehensive Cardiovascular Health Plan

While MSM shows promise in supporting cardiovascular health, it’s essential to view it as part of a holistic approach to heart health and blood pressure management. Consider the following strategies to maximize the potential benefits of MSM supplementation:

Dietary Considerations

A heart-healthy diet is crucial for maintaining optimal blood pressure and cardiovascular function. Consider incorporating the following dietary habits:

  • Increase consumption of fruits, vegetables, and whole grains
  • Choose lean proteins and plant-based protein sources
  • Limit saturated and trans fats
  • Reduce sodium intake
  • Incorporate foods rich in potassium, magnesium, and calcium

These dietary changes can work synergistically with MSM supplementation to support overall cardiovascular health.

Lifestyle Modifications

In addition to dietary changes and MSM supplementation, consider implementing the following lifestyle modifications:

  1. Regular physical activity: Aim for at least 150 minutes of moderate-intensity aerobic exercise per week
  2. Stress management: Practice relaxation techniques such as meditation, yoga, or deep breathing exercises
  3. Adequate sleep: Prioritize 7-9 hours of quality sleep per night
  4. Limit alcohol consumption and quit smoking
  5. Maintain a healthy weight through a balanced diet and regular exercise

These lifestyle factors can significantly impact cardiovascular health and may enhance the potential benefits of MSM supplementation.

Future Directions in MSM Research for Cardiovascular Health

As interest in MSM’s potential cardiovascular benefits continues to grow, researchers are exploring new avenues for investigation and application. Some promising areas of future research include:

Mechanism of Action Studies

While several mechanisms have been proposed to explain MSM’s effects on cardiovascular health, further research is needed to elucidate the precise pathways involved. Advanced molecular and cellular studies may provide deeper insights into how MSM interacts with various physiological systems to influence blood pressure and vascular function.

Long-term Safety and Efficacy Trials

Many existing studies on MSM’s cardiovascular effects have been relatively short-term. Long-term clinical trials are necessary to assess the safety and efficacy of MSM supplementation over extended periods, particularly for individuals with chronic cardiovascular conditions.

Combination Therapies

Investigating the potential synergistic effects of MSM with other natural compounds or conventional medications could lead to more effective treatment strategies for hypertension and related cardiovascular issues. Researchers may explore combinations of MSM with other supplements known to support heart health, such as omega-3 fatty acids, coenzyme Q10, or plant-based antioxidants.

Personalized Medicine Approaches

As our understanding of individual genetic and metabolic variations grows, researchers may explore how these factors influence the response to MSM supplementation. This could lead to more personalized recommendations for MSM use in cardiovascular health management.

Novel Delivery Methods

Developing new formulations and delivery methods for MSM could enhance its bioavailability and efficacy. Researchers may investigate time-release formulations, topical applications, or novel combinations with other compounds to optimize MSM’s cardiovascular benefits.

As research in these areas progresses, our understanding of MSM’s role in cardiovascular health will continue to evolve, potentially leading to more targeted and effective applications of this intriguing compound in the management of blood pressure and overall heart health.

The Effect of Daily Methylsulfonylmethane (MSM) Consumption on High-Density Lipoprotein Cholesterol in Healthy Overweight and Obese Adults: A Randomized Controlled Trial

1. Ogden C.L., Flegal K.M. Prevalence of Obesity Among Adults and Youth: United States, 2011–2014. NCHS Data Brief. 2015;131:1–8. [PubMed] [Google Scholar]

2. Fève B., Bastard J.-P. The Role of Interleukins in Insulin Resistance and Type 2 Diabetes Mellitus. Nat. Rev. Endocrinol. 2009;5:305–311. doi: 10.1038/nrendo.2009.62. [PubMed] [CrossRef] [Google Scholar]

3. Suzuki T., Katz R., Jenny N.S., Zakai N.A., LeWinter M.M., Barzilay J.I., Cushman M. Metabolic Syndrome, Inflammation, and Incident Heart Failure in the Elderly: The Cardiovascular Health Study. Circ. Heart Fail. 2008;1:242–248. doi: 10.1161/CIRCHEARTFAILURE.108.785485. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

4. Savini I., Catani M.V., Evangelista D., Gasperi V., Avigliano L. Obesity-Associated Oxidative Stress: Strategies Finalized to Improve Redox State. Int. J. Mol. Sci. 2013;14:10497–10538. doi: 10.3390/ijms140510497. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

5. Fang L., Ellims A.H., Beale A.L., Taylor A.J., Murphy A., Dart A.M. Systemic Inflammation Is Associated with Myocardial Fibrosis, Diastolic Dysfunction, and Cardiac Hypertrophy in Patients with Hypertrophic Cardiomyopathy. Am. J. Transl. Res. 2017;9:5063–5073. [PMC free article] [PubMed] [Google Scholar]

6. Bahrami H., Bluemke D.A., Kronmal R., Bertoni A.G., Lloyd-Jones D.M., Shahar E., Szklo M., Lima J.A.C. Novel Metabolic Risk Factors for Incident Heart Failure and Their Relationship with Obesity: The MESA (Multi-Ethnic Study of Atherosclerosis) Study. J. Am. Coll. Cardiol. 2008;51:1775–1783. doi: 10.1016/j.jacc.2007.12.048. [PubMed] [CrossRef] [Google Scholar]

7. Visser M., Bouter L.M., McQuillan G.M., Wener M.H., Harris T.B. Elevated C-Reactive Protein Levels in Overweight and Obese Adults. JAMA. 1999;282:2131–2135. doi: 10.1001/jama.282.22. 2131. [PubMed] [CrossRef] [Google Scholar]

8. Wee C.C., Mukamal K.J., Huang A., Davis R.B., McCarthy E.P., Mittleman M.A. Obesity and C-Reactive Protein Levels among White, Black, and Hispanic US Adults. Obesity. 2008;16:875–880. doi: 10.1038/oby.2008.7. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

9. Eckel N., Meidtner K., Kalle-Uhlmann T., Stefan N., Schulze M.B. Metabolically Healthy Obesity and Cardiovascular Events: A Systematic Review and Meta-Analysis. Eur. J. Prev. Cardiol. 2016;23:956–966. doi: 10.1177/2047487315623884. [PubMed] [CrossRef] [Google Scholar]

10. Bell J.A., Kivimaki M., Hamer M. Metabolically Healthy Obesity and Risk of Incident Type 2 Diabetes: A Meta-Analysis of Prospective Cohort Studies. Obes. Rev. Off. J. Int. Assoc. Study Obes. 2014;15:504–515. doi: 10.1111/obr.12157. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

11. Bañuls C., Rovira-Llopis S., Lopez-Domenech S., Diaz-Morales N., Blas-Garcia A., Veses S., Morillas C. , Victor V.M., Rocha M., Hernandez-Mijares A. Oxidative and Endoplasmic Reticulum Stress Is Impaired in Leukocytes from Metabolically Unhealthy vs Healthy Obese Individuals. Int. J. Obes. 2017;41:1556–1563. doi: 10.1038/ijo.2017.147. [PubMed] [CrossRef] [Google Scholar]

12. Esser N., L’homme L., De Roover A., Kohnen L., Scheen A.J., Moutschen M., Piette J., Legrand-Poels S., Paquot N. Obesity Phenotype Is Related to NLRP3 Inflammasome Activity and Immunological Profile of Visceral Adipose Tissue. Diabetologia. 2013;56:2487–2497. doi: 10.1007/s00125-013-3023-9. [PubMed] [CrossRef] [Google Scholar]

13. Opio J., Croker E., Odongo G.S., Attia J., Wynne K., McEvoy M. Metabolically Healthy Overweight/Obesity Are Associated with Increased Risk of Cardiovascular Disease in Adults, Even in the Absence of Metabolic Risk Factors: A Systematic Review and Meta-Analysis of Prospective Cohort Studies. Obes. Rev. 2020;21:e13127. doi: 10.1111/obr.13127. [PubMed] [CrossRef] [Google Scholar]

14. Bogers R.P., Bemelmans W.J.E., Hoogenveen R.T., Boshuizen H.C., Woodward M., Knekt P., van Dam R.M., Hu F.B., Visscher T.L.S., Menotti A., et al. Association of Overweight with Increased Risk of Coronary Heart Disease Partly Independent of Blood Pressure and Cholesterol Levels: A Meta-Analysis of 21 Cohort Studies Including More Than 300,000 Persons. Arch. Intern. Med. 2007;167:1720–1728. doi: 10.1001/archinte.167.16.1720. [PubMed] [CrossRef] [Google Scholar]

15. Alberti K.G.M.M., Eckel R.H., Grundy S.M., Zimmet P.Z., Cleeman J.I., Donato K.A., Fruchart J.C., James W.P.T., Loria C.M., Smith S.C. Harmonizing the Metabolic Syndrome: A Joint Interim Statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; And International Association for the Study of Obesity. Circulation. 2009;120:1640–1645. doi: 10.1161/CIRCULATIONAHA. 109.192644. [PubMed] [CrossRef] [Google Scholar]

16. Franz M.J., Boucher J.L., Rutten-Ramos S., VanWormer J.J. Lifestyle Weight-Loss Intervention Outcomes in Overweight and Obese Adults with Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. J. Acad. Nutr. Diet. 2015;115:1447–1463. doi: 10.1016/j.jand.2015.02.031. [PubMed] [CrossRef] [Google Scholar]

17. Stefan N., Häring H.-U., Schulze M.B. Metabolically Healthy Obesity: The Low-Hanging Fruit in Obesity Treatment? Lancet Diabetes Endocrinol. 2018;6:249–258. doi: 10.1016/S2213-8587(17)30292-9. [PubMed] [CrossRef] [Google Scholar]

18. Nakhostin-Roohi B., Barmaki S., Khoshkhahesh F., Bohlooli S. Effect of Chronic Supplementation with Methylsulfonylmethane on Oxidative Stress Following Acute Exercise in Untrained Healthy Men. J. Pharm. Pharmacol. 2011;63:1290–1294. doi: 10.1111/j.2042-7158.2011.01314.x. [PubMed] [CrossRef] [Google Scholar]

19. Kim Y.H., Kim D.H., Lim H., Baek D.-Y. , Shin H.-K., Kim J.-K. The Anti-Inflammatory Effects of Methylsulfonylmethane on Lipopolysaccharide-Induced Inflammatory Responses in Murine Macrophages. Biol. Pharm. Bull. 2009;32:651–656. doi: 10.1248/bpb.32.651. [PubMed] [CrossRef] [Google Scholar]

20. Ahn H., Kim J., Lee M.-J., Kim Y.J., Cho Y.-W., Lee G.-S. Methylsulfonylmethane Inhibits NLRP3 Inflammasome Activation. Cytokine. 2015;71:223–231. doi: 10.1016/j.cyto.2014.11.001. [PubMed] [CrossRef] [Google Scholar]

21. Miller L.E. Methylsulfonylmethane Decreases Inflammatory Response to Tumor Necrosis Factor-α in Cardiac Cells. Am. J. Cardiovasc. Dis. 2018;8:31–38. [PMC free article] [PubMed] [Google Scholar]

22. Bertoni A.G., Burke G.L., Owusu J.A., Carnethon M.R., Vaidya D., Barr R.G., Jenny N.S., Ouyang P., Rotter J.I. Inflammation and the Incidence of Type 2 Diabetes: The Multi-Ethnic Study of Atherosclerosis (MESA) Diabetes Care. 2010;33:804–810. doi: 10.2337/dc09-1679. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

23. Sousa-Lima I., Park S.-Y., Chung M., Jung H.J., Kang M.-C., Gaspar J.M., Seo J.A., Macedo M.P., Park K.S., Mantzoros C., et al. Methylsulfonylmethane (MSM), an Organosulfur Compound, Is Effective against Obesity-Induced Metabolic Disorders in Mice. Metabolism. 2016;65:1508–1521. doi: 10.1016/j.metabol.2016.07.007. [PubMed] [CrossRef] [Google Scholar]

24. Rubenstein J.H., Morgenstern H., Kellenberg J., Kalish T., Donovan J., Inadomi J., McConnell D., Stojanovska J., Schoenfeld P. Validation of a New Physical Activity Questionnaire for a Sedentary Population. Dig. Dis. Sci. 2011;56:2678–2687. doi: 10.1007/s10620-011-1641-y. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

25. Subar A.F., Kirkpatrick S.I., Mittl B., Zimmerman T.P., Thompson F.E., Bingley C., Willis G., Islam N.G., Baranowski T., McNutt S., et al. The Automated Self-Administered 24-Hour Dietary Recall (ASA24): A Resource for Researchers, Clinicians, and Educators from the National Cancer Institute. J. Acad. Nutr. Diet. 2012;112:1134–1137. doi: 10.1016/j.jand.2012.04.016. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

26. Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., Turner R.C. Homeostasis Model Assessment: Insulin Resistance and β-Cell Function from Fasting Plasma Glucose and Insulin Concentrations in Man. Diabetologia. 1985;28:412–419. doi: 10.1007/BF00280883. [PubMed] [CrossRef] [Google Scholar]

27. Wallace T.M., Levy J.C., Matthews D.R. Use and Abuse of HOMA Modeling. Diabetes Care. 2004;27:1487–1495. doi: 10.2337/diacare.27.6.1487. [PubMed] [CrossRef] [Google Scholar]

28. Lin L., Ma D., Bloomer R., Butawan M., Smith W.A., Yates C.R. Development and Application of an LC-MS/MS Method for Determining Methylsulfonylmethane (MSM) Levels in Human Plasma. J Nutr Food Sci. 2020;10:773. [Google Scholar]

29. Luo X., Chae M., Krishnakumar R., Danko C.G., Kraus W. Dynamic Reorganization of the AC16 Cardiomyocyte Transcriptome in Response to TNFα Signaling Revealed by Integrated Genomic Analyses. BMC Genom. 2014;15:155. doi: 10.1186/1471-2164-15-155. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

30. Gordon D.J., Probstfield J.L., Garrison R.J., Neaton J.D., Castelli W.P., Knoke J.D., Jacobs D.R., Bangdiwala S., Tyroler H.A. High-Density Lipoprotein Cholesterol and Cardiovascular Disease. Four Prospective American Studies. Circulation. 1989;79:8–15. doi: 10.1161/01.CIR.79.1.8. [PubMed] [CrossRef] [Google Scholar]

31. Pirillo A., Catapano A.L., Norata G.D. Biological Consequences of Dysfunctional HDL. Curr. Med. Chem. 2019;26:1644–1664. doi: 10.2174/0929867325666180530110543. [PubMed] [CrossRef] [Google Scholar]

32. van der Merwe M., Bloomer R.J. The Influence of Methylsulfonylmethane on Inflammation-Associated Cytokine Release before and Following Strenuous Exercise. J. Sports Med. 2016;2016:7498359. doi: 10.1155/2016/7498359. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

33. Morishima A., Ohkubo N., Maeda N., Miki T., Mitsuda N. NFkappaB Regulates Plasma Apolipoprotein A-I and High Density Lipoprotein Cholesterol through Inhibition of Peroxisome Proliferator-Activated Receptor Alpha. J. Biol. Chem. 2003;278:38188–38193. doi: 10.1074/jbc.M306336200. [PubMed] [CrossRef] [Google Scholar]

34. Puzianowska-Kuźnicka M., Owczarz M., Wieczorowska-Tobis K., Nadrowski P., Chudek J., Slusarczyk P., Skalska A., Jonas M., Franek E., Mossakowska M. Interleukin-6 and C-Reactive Protein, Successful Aging, and Mortality: The PolSenior Study. Immun. Ageing. 2016;13:21. doi: 10.1186/s12979-016-0076-x. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

35. Barmaki S., Bohlooli S., Khoshkhahesh F., Nakhostin-Roohi B. Effect of Methylsulfonylmethane Supplementation on Exercise—Induced Muscle Damage and Total Antioxidant Capacity. J. Sports Med. Phys. Fitness. 2012;52:170–174. [PubMed] [Google Scholar]

36. Nakhostin-Roohi B., Niknam Z., Vaezi N., Mohammadi S., Bohlooli S. Effect of Single Dose Administration of Methylsulfonylmethane on Oxidative Stress Following Acute Exhaustive Exercise. Iran J. Pharm. Res. 2013;12:845–853. [PMC free article] [PubMed] [Google Scholar]

37. Gupta S., Young D., Maitra R.K., Gupta A., Popovic Z.B., Yong S.L., Mahajan A., Wang Q., Sen S. Prevention of Cardiac Hypertrophy and Heart Failure by Silencing of NF-KappaB. J. Mol. Biol. 2008;375:637–649. doi: 10.1016/j.jmb.2007.10.006. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

38. Zhong P., Wu L., Qian Y., Fang Q., Liang D., Wang J., Zeng C., Wang Y., Liang G. Blockage of ROS and NF-ΚB-Mediated Inflammation by a New Chalcone L6H9 Protects Cardiomyocytes from Hyperglycemia-Induced Injuries. Biochim. Biophys. Acta. 2015;1852:1230–1241. doi: 10.1016/j.bbadis.2015.02.011. [PubMed] [CrossRef] [Google Scholar]

39. Rubiś P., Wiśniowska-Smiałek S., Wypasek E., Rudnicka-Sosin L., Hlawaty M., Leśniak-Sobelga A., Kostkiewicz M., Podolec P. 12-Month Patterns of Serum Markers of Collagen Synthesis, Transforming Growth Factor and Connective Tissue Growth Factor Are Similar in New-Onset and Chronic Dilated Cardiomyopathy in Patients Both with and without Cardiac Fibrosis. Cytokine. 2017;96:217–227. doi: 10.1016/j.cyto.2017.04.021. [PubMed] [CrossRef] [Google Scholar]

MSM (Methylsulfonylmethane): Uses and Risks

Written by Annie Stuart

  • Why do people take MSM?
  • Can you get MSM naturally from foods
  • What are the risks of taking MSM?

MSM is a chemical in animals, humans, and many plants. People use it most often to try to treat arthritis.

MSM can be produced in a lab, where it is sometimes combined with other supplements such as glucosamine or chondroitin.

People take MSM by mouth or apply it to the skin, mostly using it to lessen inflammation.

They take MSM to try to relieve pain or swelling from:

  • Osteoarthritis or rheumatoid arthritis
  • Bursitis, tendinitis, or tenosynovitis

People also apply MSM to the skin to try to treat problems such as:

  • Scar tissue or stretch marks
  • Wrinkles
  • Wind or sun burn
  • Wounds, cuts, or abrasions
  • Rosacea

Or they may take it to try to treat gastrointestinal problems such as:

  • Chronic constipation
  • Ulcers
  • Diverticulosis (a bowel disease)
  • Hemorrhoids

There is a whole range of other reasons people take MSM. This includes obesity and liver problems, high blood pressure, high cholesterol, gum disease, snoring, infections, lung problems, Alzheimer’s, HIV, and cancer.

The evidence to support taking MSM for these is lacking.

However, there is evidence that MSM in combination with other supplements may help a bit with the pain and swelling of knee osteoarthritis. Also, early animal research shows some promise for decreasing joint degeneration.

Limited small studies also show that MSM may help with exercise recovery. But researchers have more work to do to confirm this.

MSM has shown some effectiveness for treating allergies, repetitive stress injuries, certain bladder disorders like interstitial cystitis, and wounds, but more research is needed before it can be recommended for any of these conditions.

People have tried taking from 500 milligrams of MSM twice times daily to 3 grams once daily for osteoarthritis. However, optimal doses of MSM have not been set for any condition. And quality and active ingredients in supplements may vary widely from maker to maker. This makes it hard to set a standard dose.

Very small amounts of MSM can be found in:

  • Fruit
  • Corn
  • Tomatoes
  • Tea and coffee
  • Milk

But the amounts in these foods are a small fraction of the amount in supplements.

Chances are it is safe if you take up to 6 grams of MSM by mouth for six months or fewer.

Side effects. There isn’t enough information about MSM’s safety when you apply it to the skin.

So far, studies have shown minimal side effects when MSM is taken orally in a dosage of 3 grams daily for six months, but some people may experience mild gastrointestinal side effects such as discomfort or diarrhea.

Risks. Don’t take any chances if you are pregnant or breastfeeding. Doctors don’t know enough about the safety of MSM in these circumstances. So it’s best not to take it. Don’t take any chances if you are pregnant or breastfeeding. Doctors don’t know enough about the safety of MSM in these circumstances. So, it’s best not to take it. 

Interactions. There doesn’t appear to be an interaction between MSM and medications, herbs, supplements, or foods.

The FDA does not regulate supplements. Be sure to tell your doctor about any supplements you’re taking, even if they’re natural. That way, they can check on any potential side effects or interactions with medications, foods, or other herbs and supplements. Your doctor can let you know if the supplement might raise your risks.

Top Picks

What vitamins can increase blood pressure

November 19
2021

Vitamins are very important for a normal existence and a fulfilling life. But it is important to take a responsible approach to the choice of valuable substances, as some of them can increase or decrease the pressure. In some cases, if there are problems with pressure, the intake of one or another should be strictly controlled, especially when it comes to additives. High quality preparations can be found in our online store. Each of the options offered in dobavki.ua is a product from trusted manufacturers that meets international standards and GOST.

Which vitamins increase blood pressure?

Various vitamins help to increase blood pressure. Among them, the following are particularly effective:

  • PP;
  • C;
  • B12;
  • E;
  • B1;
  • B6;
  • B2.

More details on the website.

Various microelements are also useful for solving the problem, among which fluorine, magnesium, calcium, potassium, iron, zinc, phosphorus are distinguished. No less useful are tannins and moderate amounts of caffeine, which, in particular, is found in black tea and coffee.

Other foods that contain valuable vitamins and minerals and answer the question which vitamins increase blood pressure are salt, spices and sodium supplements, cocoa, meat products, baked goods, full fat dairy products, cheese, sweets, foods, eliminating anemia.

New Chapter (Blood Pressure) Blood Pressure Support is available to help maintain healthy blood pressure levels, improve blood vessel function, and modulate important metabolic functions. An alternative may be the supplement “Blood Pressure Support” Dr. Mercola (Blood Pressure) with a safe formulation.

Which vitamins lower blood pressure?

Reducing blood pressure – quite often necessary for people who suffer from high rates. The following vitamins can help with this:

  • A;
  • B6;
  • B5;
  • B9;
  • PP;
  • R;
  • H.

They are found in various foods. Particularly useful for reducing pressure will be: celery, sea oily fish, cottage cheese, baked potatoes, garlic, walnuts, bran, viburnum, cranberries, hawthorn, black currants, rose hips, oatmeal, bananas. The main thing is to use such products carefully and not in excessive quantities.

Potassium, cobalt, manganese, copper, chlorine, phosphorus, sodium, selenium, magnesium, zinc, etc. can be distinguished among valuable trace elements. The balance of all valuable substances is important to alleviate the condition with increased pressure and general normalization of well-being.

For general wellness, it is useful to include vitamins in the diet in the form of supplements in the recommended proportions. They will also have a beneficial effect on the body as a whole.

Specific drugs include:

  • RidgeCrest Herbals Blood Pressure Complex, which is useful for high blood pressure, atherosclerosis, heart and vascular diseases, high blood cholesterol, weak immunity;
  • “Complex for normalization of blood pressure”, IpertenVin, Erbenobili in drops, which lowers blood pressure, lowers cholesterol levels in the blood, alleviates the symptoms of atherosclerosis, cardiovascular diseases, strengthens the immune system;
  • “Complex for normalizing blood pressure”, Targeted Choice, Bluebonnet Nutrition, which is needed by hypertensive patients, people with high blood cholesterol levels, weakened immune systems, atherosclerosis, blood and vascular diseases.

Any of the products is certified and safe to use, and most importantly – it answers the question of which vitamins reduce blood pressure.

What vitamins normalize blood pressure?

There are vitamins that help normalize blood pressure. Moreover, they help both to increase and to decrease. Their feature is to increase the elasticity and patency of blood vessels. As a result, pressure normalizes, the general condition of the body improves, and metabolic processes are activated.

Particularly valuable and important vitamins include:

  • A;
  • C;
  • E;
  • PP.

More details on the website.

Finding out which vitamins normalize blood pressure, you can choose the following drugs, such as:

  1. Healthy Blood Pressure Support Formula, Swanson with the best plant extracts and high quality proteins in the composition;
  2. “Vitamins to support the cardiovascular system” Now Foods Blood Pressure Health, which allows you to normalize blood pressure to healthy levels;
  3. Blood Pressure Support, Dr. Mercola to guarantee normal well-being and healthy performance;
  4. Enzymatic Therapy Blood Pressure Support is pure, safe and natural.

If you have low or high blood pressure, vitamins will help to eliminate negative manifestations. Give preference to certified high quality products from trusted manufacturers. Affordable prices and same day shipping.

Sources

  1. https://pubmed.ncbi.nlm.nih.gov/30081527/
  2. https://pubmed.ncbi.nlm.nih.gov/27845713/
  3. https://pubmed.ncbi.nlm.nih.gov/19954568/
  4. https://pubmed.ncbi.nlm.nih.gov/14972086/

Share

Share

Share

Share

New comment

Sign in with

Submit

what it is and what it is used for – Lamyra

Science and medicine do not stand still, every day scientists develop new drugs and methods for the treatment of various diseases, including diseases of the musculoskeletal system.

In this article, we want to tell you about MSM or organic sulfur, which has a powerful therapeutic effect in the treatment of joint pathologies, osteochondrosis, and is also a safe pain reliever of natural origin.

Natural Origin MCM

Sulfur is a microelement that has its own cycle in nature. MSM is one of the richest sources of sulfur found in a number of fruits, vegetables and grains, in the form of the amino acids methionine and cysteine. The characteristic smell of onions, garlic and horseradish is due to the sulfur that is part of them. And our hair curls thanks to the sulfur bonds of the amino acid cysteine. Hair straighteners are designed to break sulfur bonds. Sulfur is a mineral that we get from food, and which is sorely lacking in the diet of modern residents. The intake of MSM in the body normalizes the vital activity of key amino acids in the body, and their deficiency leads to the occurrence of physical and mental pathologies.

How our body uses sulfur

We all know that without substances such as air and water, human life is impossible. It turns out that sulfur also belongs to such vital substances.

Sulfur is needed to form of all connective tissues in the body. Without sulfur constituents, we (and other living beings) would be only formless puddles of protoplasm.

Sulfur provides structure, the delivery of nutrients and oxygen to the cell, the effectiveness of the protective properties of mucous membranes, the ability of the intestine to absorb all the nutrients, the elasticity of blood vessels and skin, and promotes healing processes.

MSM is an essential component in the treatment of joint pathologies. Most often, the supplement is used to relieve pain in the joints and muscles. The pain-relieving effect of MSM not only helps to fight the symptoms of arthritis, but also has a powerful anti-inflammatory effect.

In addition, MSM contributes to the restoration and treatment of cartilage, since it is a necessary element for the production of its own glycosaminoglycans – the building material for ligaments, tendons, synovial fluid, etc. The use of a dietary supplement allows you to reduce pain impulses without side effects and increases the mobility and flexibility of the joints. The combined use of MSM and glucosamine increases the effectiveness in the fight against osteoarthritis.

Sulfur is often referred to as the “beauty mineral” for its ability to stimulate collagen and keratin production in the body. It is necessary in order to have thick shiny hair, soft skin and healthy strong nails.

Sulfur is one of the indispensable macronutrients, it is part of nervous and cerebral tissue . Taurine is an essential sulfuric amino acid involved in the formation of neurotransmitters, is responsible for our mood and blood pressure. Additional intake of taurine is especially necessary for women , since the female hormone estradiol suppresses the formation of taurine in the liver. Any additional intake of estradiol in the body, for example, in the form of a drug, further enhances this effect.

Also, sulfur is one of the main components in the process of insulin production, and plays an important role in the metabolism of sugar. This substance is especially needed for the treatment of patients suffering from diabetes and hypoglycemia.

Sulfur is a regulator and activator of vitamins B 1 , B 5 , B 7 , vitamin C. Without it, these vitamins are poorly absorbed.

Signs of lack of sulfur in the body
  • Decreased mobility and flexibility of the joints (crunching in the joints and spine)
  • Muscle weakness and muscle pain
  • Deterioration of the skin: it becomes dull and inelastic
  • Hair loss, brittle nails
  • Liver, pancreatic function, diabetes mellitus may be impaired
  • Reduced immunity and greater susceptibility to disease

In order for sulfur to be absorbed, it must be in a bioavailable form

Although MCM is a naturally occurring substance, its concentration in food sources is hundreds of parts per million, which is not enough to fully compensate for the need for it from food.

Synthetically produced MSM allows you to take biologically active amounts without having to consume unrealistic amounts of food, and is no different in structure and safety from the naturally occurring compound.

Safety of use and daily doses

MSM is considered to be so safe, almost as safe as water, and does not cause significant side effects, does not give an unpleasant smell to the body or breath, even when used in large doses. The daily dose may vary from 250 to 20 grams depending on body weight, health status and duration of the disease. However, most commonly used is 1500-3000 mg per day.

Food supplement MCM is FDA (Food and Drug Administration) approved and has GRAS (Generally Recognized as Safe) status up to 4845.6mg/day.

Outwardly, MSM resembles sugar, dissolves easily in water or juice, and has a slightly bitter taste.

MCM should be taken with at breakfast and/or lunch, and in any case avoid taking on an empty stomach as it may have a laxative effect.

Mechanism of action MCM

MSM is a highly soluble substance; when it enters the human body, it easily penetrates into the cells and has an anti-inflammatory, antioxidant and immunomodulatory effect. It reduces the activity of inflammatory cells, inhibits the production of reactive oxygen species and helps to remove free radicals that have a damaging effect on the body. Modulates the immune response through cross-talk between oxidative stress and inflammation.

It is interesting that the sensations from taking it come on quite quickly, during the first week: the pain syndrome in the joints and muscles decreases, the range of motion increases, and muscle spasms decrease.

An interesting fact is that during the study, which lasted more than 7 months, the improvement in results continued even after six months.

Indications for use MCM

Arthritis (osteoarthritis)

As we age, wear and tear on the body’s joints leads to osteoarthritis, or, in medical parlance, degenerative joint disease. MCM has been scientifically proven to be ideal for the non-toxic treatment of osteoarthritis. With its analgesic and anti-inflammatory properties, it can reduce pain, slow down the destruction of cartilage tissue, and improve blood circulation. MSM is not only well tolerated, it is as active as pharmaceutical analgesics. But unlike them, MSM is non-toxic and has no side effects.

For rheumatoid arthritis

This disease is considered the lot of the elderly and according to statistics, 40% of people over 60 suffer from some form of rheumatoid arthritis. However, it can occur at any age. The autoimmune nature of the disease involves a malfunction of the immune system, its activity against its own body. In this case, MSM reacts as an anti-inflammatory and analgesic agent, allows you to achieve disease control and reach long-term remissions.

For pain relief and speedy recovery

MCM improves tissue blood supply, saturates them with oxygen and provides nutrients to wounds, scars, and inflammations. The anti-inflammatory and analgesic effects of the supplement help to relieve symptoms and speed up the healing process.

For muscular rheumatism (fibriomyalgia)

The use of the supplement can alleviate the condition with muscular rheumatism. Taking MCM regularly can soothe pain and be an effective, safe source of relief.

For problems with teeth and gums

MCM can be an additional weapon in the fight against gum disease, such as gingivitis and various inflammations.

For back pain

According to the results of the treatment of hundreds of patients, it can be said with confidence that MSM is effective in treating back pain caused by osteochondrosis, disc degeneration, etc.

MSM for athletes

The professional activity of athletes is often accompanied by injuries, sprains and requires special care and recovery measures. In this case, MSM helps to shorten the recovery period of the body after strenuous resistance and endurance exercises, reduce muscle pain, maintain normal cartilage in the joints, contributing to the production of its own glycosaminoglycans.

For hair loss and skin problems

Taking MCM has a positive effect on the condition of the skin, hair and nails, promotes the production of collagen and keratin. Cosmetologists, dermatologists and trichologists often recommend MCM to their patients.

New generation of chondroprotectors

For the treatment of joint pathology, doctors often recommend taking chondroprotectors – a group of drugs used to treat and improve the function of damaged joints.

Restobon and RestoFLEX are new generation chondroprotectors. The main active ingredient is MSM – a new trend in maintaining joint health.

The preparations contain a complex of substances that help strengthen muscles, joints and bones.

Restobon – a complex of MSM, glucosamine sulfate, collagen, calcium and vitamin D 3 , is used to restore and improve the function of joints, cartilage and bone tissue.

RestoFLEX – a complex of magnesium and MSM, is recommended to be used to eliminate muscle spasms, accelerate recovery after physical exertion, increase flexibility and mobility of joints and ligaments.