What are the traditional uses of gotu kola. How does gotu kola benefit venous insufficiency and wound healing. Can gotu kola help with anxiety and other health conditions.

The Rich History and Traditional Uses of Gotu Kola

Gotu kola (Centella asiatica) boasts a long and storied history in traditional medicine systems across Asia. For millennia, healers in India, China, and Indonesia have turned to this humble herb for its remarkable healing properties. But what exactly did they use it for?

Gotu kola’s traditional applications were diverse and far-reaching:

• Wound healing
• Enhancing mental clarity
• Treating skin conditions like leprosy and psoriasis
• Combating respiratory infections
• Managing syphilis and hepatitis
• Soothing stomach ulcers
• Alleviating mental fatigue
• Controlling epilepsy
• Treating diarrhea and fever
• Easing asthma symptoms

Perhaps most intriguingly, gotu kola earned the moniker “fountain of life” due to a captivating legend. It’s said that an ancient Chinese herbalist lived for over two centuries, attributing his longevity to the regular consumption of gotu kola. While we can’t verify this claim, it speaks to the reverence this herb has commanded throughout history.

Gotu Kola’s Modern Applications in Western Medicine

Today, gotu kola has found its way into Western medical practices, albeit with a more focused set of applications. In the United States and Europe, practitioners primarily recommend gotu kola for two key purposes:

1. Treating varicose veins
2. Managing chronic venous insufficiency (a condition where blood pools in the legs)

Additionally, gotu kola has gained traction in topical treatments. Many practitioners incorporate it into ointments designed to:

• Alleviate psoriasis symptoms
• Promote the healing of minor wounds

Distinguishing Gotu Kola from Kola Nut

It’s crucial to note that gotu kola is distinct from kola nut (Cola nitida). Unlike its namesake, gotu kola contains no caffeine and does not act as a stimulant. This fundamental difference sets it apart in terms of both its effects and potential applications.

The Botanical Profile of Gotu Kola

Understanding the physical characteristics and native habitat of gotu kola can provide valuable context for its medicinal uses. So, what does this plant look like, and where does it thrive?

Gotu kola is a perennial plant with a wide distribution across the tropical and subtropical regions of the world. Its native range includes:

• India
• Japan
• China
• Indonesia
• South Africa
• Sri Lanka
• South Pacific islands

Botanically, gotu kola belongs to the parsley family, though it lacks the distinctive taste and aroma associated with its cousins. The plant has a strong affinity for water, often found growing in and around aquatic environments.

Physical Characteristics

Gotu kola’s appearance is quite distinctive:

• Leaves: Small and fan-shaped, with a vibrant green color
• Flowers: White or light purple-to-pink in hue
• Fruit: Small and oval-shaped

For medicinal purposes, herbalists primarily utilize the leaves and stems of the gotu kola plant. These parts contain the highest concentration of the herb’s bioactive compounds.

Gotu Kola’s Promising Effects on Venous Health

One of the most well-researched applications of gotu kola in modern medicine is its potential to improve venous health. But how exactly does it work, and what evidence supports its use?

Venous insufficiency occurs when blood vessels lose their elasticity, causing blood to pool in the legs and fluid to leak out of the blood vessels. This leads to swelling and discomfort. Several small-scale studies have indicated that gotu kola may help address these issues:

• Reduced swelling: Gotu kola appears to decrease leg swelling associated with venous insufficiency.
• Improved blood flow: The herb may enhance circulation in affected areas.
• Decreased fluid leakage: Studies using ultrasound have shown that gotu kola can reduce the amount of fluid leaking from blood vessels in people with varicose veins.

Clinical Evidence

A study involving 94 participants with venous insufficiency found that those taking gotu kola experienced improved symptoms compared to those receiving a placebo. This suggests that the herb may have real, measurable benefits for people struggling with this condition.

Potential for Travel-Related Swelling

Interestingly, one study explored gotu kola’s potential to prevent swelling during air travel. Participants who took gotu kola before flying experienced less ankle and leg swelling than those who did not. This finding could have implications for frequent flyers or those prone to travel-related edema.

Gotu Kola’s Role in Wound Healing and Skin Health

The potential of gotu kola to promote wound healing and improve skin health has garnered significant attention from researchers. But what mechanisms underlie these effects, and how strong is the evidence supporting them?

At the heart of gotu kola’s wound-healing properties are compounds called triterpenoids. Animal and laboratory studies have revealed several ways these chemicals may contribute to the healing process:

• Strengthening skin tissue
• Boosting antioxidant activity in wounds
• Increasing blood supply to the affected area

These findings have led to the development of topical gotu kola preparations for various skin-related issues:

1. Minor burns
2. Psoriasis
3. Scar prevention after surgery
4. Reduction or prevention of stretch marks

Many commercial creams now incorporate gotu kola as an active ingredient for wound healing. However, it’s essential to consult with a healthcare provider before using any new topical treatment, especially for persistent or severe skin conditions.

Exploring Gotu Kola’s Potential Mental Health Benefits

While gotu kola’s effects on physical health are well-documented, emerging research suggests it may also have applications in mental health. But what does the evidence say about gotu kola’s impact on anxiety and cognitive function?

Anxiety Reduction

The same triterpenoids that contribute to gotu kola’s wound-healing properties may also play a role in reducing anxiety. Animal studies have shown that these compounds can decrease anxiety-like behaviors in mice. But how does this translate to humans?

One intriguing human study found that participants who took gotu kola were less likely to be startled by a sudden noise compared to those who received a placebo. Researchers use the startle response as one way to measure anxiety levels, suggesting that gotu kola might help mitigate anxiety symptoms.

However, it’s crucial to note that the dose used in this study was exceptionally high. More research is needed to determine how gotu kola might be safely and effectively used to treat anxiety in clinical settings.

Cognitive Function

Some animal studies have indicated that the triterpenoids in gotu kola may enhance mental function. While these results are promising, more human studies are necessary to confirm these effects and establish appropriate dosages.

Gotu Kola’s Potential in Managing Other Health Conditions

Beyond its more well-known applications, researchers have begun exploring gotu kola’s potential to address a variety of other health concerns. While many of these studies are preliminary, they offer intriguing avenues for future research.

Scleroderma

A small study involving 13 women with scleroderma, an autoimmune condition that causes hardening of the skin, yielded promising results. Participants who took gotu kola experienced:

• Decreased joint pain
• Reduced skin hardening
• Improved finger movement

While these findings are encouraging, larger studies are needed to confirm gotu kola’s effectiveness for scleroderma.

Insomnia

Animal studies have demonstrated that gotu kola can act as a sedative. This has led some researchers to speculate about its potential as a natural sleep aid. However, human studies are necessary to determine whether gotu kola could be a safe and effective treatment for insomnia.

It’s important to note that using any herb for sleep should be done under the guidance of a healthcare professional, as improper use could potentially worsen sleep issues.

Safety Considerations and Potential Side Effects of Gotu Kola

While gotu kola has a long history of traditional use and shows promise in various health applications, it’s essential to approach its use with caution. As with any herbal supplement, there are potential risks and side effects to consider.

Common Side Effects

When taken orally, gotu kola may cause:

• Headache
• Upset stomach
• Nausea
• Dizziness

In some cases, gotu kola has been associated with liver problems. While rare, this underscores the importance of using the herb under medical supervision, especially if you have a history of liver disease.

Topical Use Considerations

When applied to the skin, gotu kola may occasionally cause:

• Skin irritation
• Burning sensation

It’s always advisable to perform a patch test before applying any new topical treatment over a large area of skin.

Interactions and Contraindications

Gotu kola may interact with certain medications or be contraindicated in some conditions:

• It may increase the effects of sedatives or anti-anxiety medications.
• Some studies suggest it could interfere with blood sugar control, which is a concern for diabetics.
• Due to its potential effects on the liver, it should be used cautiously by people taking medications that affect liver function.

Pregnant or breastfeeding women should avoid using gotu kola, as its safety in these populations has not been established.

Dosage and Administration of Gotu Kola

Determining the right dosage of gotu kola can be challenging, as it can vary depending on the specific health concern being addressed and the form of the herb being used. How should one approach using gotu kola safely and effectively?

Oral Supplementation

For oral use, common dosages range from 60 to 180 mg of gotu kola extract per day, typically divided into two or three doses. However, some studies have used much higher doses, particularly for short-term use.

Gotu kola is available in several forms for oral consumption:

• Dried herb for tea
• Capsules
• Tinctures
• Standardized extracts

Topical Application

For skin conditions, gotu kola is often used in creams or ointments containing 1% to 10% of the herb. The frequency of application can vary depending on the specific product and condition being treated.

Important Considerations

When using gotu kola, keep the following in mind:

1. Always start with the lowest effective dose and increase gradually if needed.
2. Follow the instructions on commercial products carefully.
3. Consult with a healthcare provider before starting any new supplement regimen, especially if you have pre-existing health conditions or are taking medications.
4. Be aware that the quality and potency of herbal supplements can vary widely between manufacturers. Look for products from reputable sources that have been third-party tested for purity and potency.

Remember, while gotu kola shows promise for various health applications, more research is needed to fully understand its effects and establish standardized dosing guidelines for different conditions.

Gotu kola Information | Mount Sinai

Brahmi; Centella; Centella asiatica; Hydrocotyle; Indian pennywort; Luei gong gen; Marsh pennywort

Gotu kola (Centella asiatica) has been used to treat many conditions for thousands of years in India, China, and Indonesia. It was used to heal wounds, improve mental clarity, and treat skin conditions such as leprosy and psoriasis.

Some people use it to treat respiratory infections, such as colds, and in the past it was used for that in China. It has been called “the fountain of life” because legend has it that an ancient Chinese herbalist lived for more than 200 years as a result of taking gotu kola.

Historically, gotu kola has also been used to treat syphilis, hepatitis, stomach ulcers, mental fatigue, epilepsy, diarrhea, fever, and asthma. Today, in the U.S. and Europe gotu kola is most often used to treat varicose veins and chronic venous insufficiency, a condition where blood pools in the legs. It is also used in ointments to treat psoriasis and help heal minor wounds.

Gotu kola is not the same as kola nut (Cola nitida). Unlike kola nut, gotu kola does not have caffeine, and is not a stimulant.

Plant Description

Gotu kola is a perennial plant native to India, Japan, China, Indonesia, South Africa, Sri Lanka, and the South Pacific. A member of the parsley family, it has no taste or smell. It thrives in and around water. It has small fan-shaped green leaves with white or light purple-to-pink flowers, and small oval fruit. The leaves and stems of the gotu kola plant are used as medicine.

Medicinal Uses and Indications

Treatment

Venous insufficiency and varicose veins

When blood vessels lose their elasticity, blood pools in the legs and fluid leaks out of the blood vessels. That causes the legs to swell (venous insufficiency). Several small studies suggest gotu kola may help reduce swelling and improve blood flow. In a study of 94 people with venous insufficiency, those who took gotu kola saw their symptoms improve compared to those who took placebo. In another study of people with varicose veins, ultrasound tests showed that people who took gotu kola had less leakage of fluid.

One study also found that people who took gotu kola before flying had less ankle and leg swelling than those who did not take it.

Wound healing and skin lesions

Gotu kola has chemicals called triterpenoids. In animal and lab studies, these compounds seem to help heal wounds. For example, some studies suggest that triterpenoids strengthen the skin, boost antioxidants in wounds, and increase blood supply to the area. Based on these findings, gotu kola has been applied to the skin, or used topically, for minor burns, psoriasis, preventing scars after surgery, and preventing or reducing stretch marks.

You can find gotu kola in many creams for wound healing. Ask your health care provider if one is right for you.

Anxiety

These same chemicals, triterpenoids, seem to reduce anxiety and increase mental function in mice. One human study found that people who took gotu kola were less likely to be startled by a new noise than those who took placebo. Since the “startle noise” response can be a way to tell if someone is anxious, researchers think that gotu kola might help reduce anxiety symptoms. But the dose used in this study was very high, so it is impossible to say how gotu kola might be used to treat anxiety.

Scleroderma

A single study of 13 women with scleroderma found that gotu kola decreased joint pain and skin hardening, and improved finger movement.

Insomnia

Gotu kola acts as a sedative when given to animals in tests. Because of that, it is sometimes suggested to help people with insomnia. But no human studies have been done to see whether it works or whether it is safe.

Dosage and Administration

Gotu kola is available in teas and as dried herbs, tinctures, capsules, tablets, and ointments. Products should be stored in a cool, dry place and used before the expiration date on the label.

Pediatric

Gotu kola is not recommended for children under 18 years old.

Adult

The standard dose of gotu kola (Centella asiatica) is different depending on what kind you use and what you use it for. Your health care provider can help you choose the right dose for you. Most studies have used standardized extracts:

• Dried herb: You can make a tea of the dried leaf, 3 times daily.
• Powdered herb: available in capsules
• Tincture (1:2 w/v, 30% alcohol): 30 to 60 drops (equivalent to 1.5 to 3 mL, there are 5 mL in a tsp.), 3 times daily.
• Standardized extract: 50 to 250 mg, 2 to 3 times daily. Standardized extracts should contain 40% asiaticoside, 29 to 30% asiatic acid, 29 to 30 % madecassic acid, and 1 to 2% madecassoside. Doses used in studies mentioned in the Treatment section include 20 mg for scleroderma and up to 180 mg in one study for venous insufficiency, although most of the studies for this condition used 90 to 120 mg daily.

Precautions

Gotu kola has been used in some studies that lasted up to one year. However, gotu kola has the potential to be harmful to the liver. It is best not to use gotu kola for more than 6 weeks without talking to your doctor. You may need to take a 2-week break before taking the herb again.

Asiaticoside, a major part of gotu kola, has also been link with tumor growth in mice. Anyone with a history of precancerous or cancerous skin lesions, such as squamous cell, basal cell skin cancer, or melanoma, should not use gotu kola.

People with liver disease, or who take medications that affect the liver, should not take gotu kola. Ask your doctor if you take any prescription medications, or often take over-the-counter pain relievers.

Side Effects

Side effects are rare but may include skin allergy and burning sensations with external use, headache, stomach upset, nausea, dizziness, and extreme drowsiness. These tend to happen with high doses of gotu kola.

Pediatric Use

Gotu kola is not recommended for children.

Geriatric Use

People older than 65 should take a lower dose of gotu kola. Your health care provider can help you determine the right dose for you, which can be increased slowly over time.

Interactions and Depletions

Gotu kola may interact with the following medications:

Drugs that affect the liver: Gotu kola contains things that may hurt a person’s liver, and taking it along with some other medications that also can harm the liver may cause liver damage.

Cholesterol-lowering drugs (including statins): In animal studies, gotu kola raised cholesterol levels. It may also raise cholesterol levels in humans, although no studies have been done.

Diabetes medications: In animal studies, gotu kola seems to increase blood sugar levels. People with diabetes should not take gotu kola without first talking to their doctor.

Diuretics (water pills): Gotu kola seems to act like a diuretic, meaning it helps the body get of excess fluid. Taking diuretic medications and gotu kola could cause your body to lose too much fluid, upsetting the balance of electrolytes you need. The same is true of taking gotu kola with herbs that have diuretic effects, such as green tea, astragalus, or gingko.

Sedatives: Because gotu kola acts like a sedative, it might make some drugs taken for anxiety or insomnia stronger. The same is true for herbs taken for anxiety or insomnia, such as valerian.

Supporting Research

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Belcaro GV, Rulo A, Grimaldi R. Capillary filtration and ankle edema in patients with venous hypertension treated with TTFCA. Angiology. 1990;41(1):12-18.

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Cesarone MR, Incandela L, De Sanctis MT, et al. Flight microangiopathy in medium- to long-distance flights: prevention of edema and microcirculation alterations with total triterpenic fraction of Centella asiatica. Angiology. 2001;52 Suppl 2:S33-7.

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Pointel JP, Boccalon H, Cloarec M, Ledevehat C, Joubert M. Titrated extract of centella asiatica (TECA) in the treatment of venous insufficiency of the lower limbs. Angiology. 1987;38(1 Pt 1):46-50.

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10 Benefits, Side Effects, and More

What’s gotu kola?

Pegged as the “herb of longevity,” gotu kola is a staple in traditional Chinese, Indonesian, and Ayurvedic medicine. Practitioners claim the medicinal plant has the power to boost brainpower, heal skin issues, and promote liver and kidney health — and some studies seem to agree.

Keep reading to learn how gotu kola may help improve your overall health and well-being.

A small 2016 study compared the effects of gotu kola extract and folic acid in boosting cognitive function after a stroke. This small study assessed the impact on three groups of participants — one taking 1,000 milligrams (mg) of gotu kola per day, one taking 750 mg of gotu kola per day, and one taking 3 mg of folic acid per day.

Although gotu kola and folic acid were equally beneficial in improving overall cognition, gotu kola was more effective in improving memory domain.

A separate study looked at the cognitive enhancing effects of gotu kola water extract on mice. Although both young and old mice showed improvements in learning and memory using the Morris Water Maze, the effect was higher in the older mice.

How to use: Take 750 to 1,000 mg of gotu kola per day for up to 14 days at a time.

Gotu kola has the ability to enhance memory and nerve function, which gives it potential in treating Alzheimer’s disease. In fact, one 2012 study on mice found that gotu kola extract had a positive effect on behavioral abnormalities in mice with Alzheimer’s disease.

The extract was also shown, in lab and animal studies, to have a modest effect on protecting brain cells from toxicity. This could also protect the cells from forming the plaque associated with Alzheimer’s.

Still, further research is needed to determine exactly how gotu kola could be used to treat Alzheimer’s. If you’re interested in adding this to your treatment plan, talk to your doctor before use.

How to use: Take 30 to 60 drops of liquid gotu kola extract 3 times per day. Dosages may vary between manufacturers, so always carefully follow the directions on the bottle.

Researchers in an animal study from 2016 found that gotu kola had an anti-anxiety effect on male mice that were sleep deprived for 72 hours. Sleep deprivation can cause anxiety, oxidative damage, and neuroinflammation.

Mice that were given gotu kola for five consecutive days before undergoing sleep deprivation experienced significantly less anxiety-like behavior. They also experienced improved locomotor activity and less oxidative damage.

A 2013 review of anti-anxiety herbal medicines also concluded that gotu kola has an acute anti-anxiety effect. However, more research is needed to confirm these findings.

How to use: Take 500 mg of gotu kola extract twice a day for up to 14 days at a time. You can take up to 2,000 mg per day in cases of extreme anxiety.

Gotu kola’s positive effect on brain function may also make it an effective antidepressant.

A review from 2016 supports these findings, in part due to a study on 33 people with generalized anxiety disorder. The participants were asked to take gotu kola in place of their antidepressant medication for 60 days. They self-reported decreased stress, anxiety, and depression.

Another study discussed in the review assessed the effect of gotu kola on rats induced with chronic depression. The herbal remedy had a positive effect on certain elements of behavioral depression, including body weight, body temperature, and heart rate.

How to use: Take 500 mg of gotu kola twice a day for up to 14 days at a time. You can take up to 2,000 mg per day during times of intensified depression.

Research from 2001 found that gotu kola can reduce problems with fluid retention, ankle swelling, and circulation tied to taking flights that last longer than three hours.

Participants who experienced mild-to-moderate superficial venous disease with varicose veins were asked to take gotu kola for two days before their flight, the day of their flight, and the day after their flight.

Researchers found that participants who took the supplement experienced significantly less fluid retention and ankle swelling than those who didn’t.

Older research has also shown that gotu kola can be useful in treating varicose veins. This may be because gotu kola has a positive metabolic effect on the connective tissue of the vascular wall.

How to use: Take 60 to 100 mg of gotu kola extract 3 times per day for a week, before and after any flights. You can also massage the affected area with a topical cream containing 1 percent gotu kola extract.

How to do a skin patch test: It’s important to do a patch test before using any topical medication. To do this, rub a dime-sized amount on to the inside of your forearm. If you don’t experience any irritation or inflammation within 24 hours, it should be safe to use elsewhere.

Given its perceived ability to treat anxiety, stress, and depression, gotu kola may also be used to treat the insomnia that sometimes accompanies these conditions. Some consider this herbal remedy to be a safe alternative to prescription medications used to treat insomnia and other sleep disorders.

Although older research does suggest that gotu kola can help treat sleep disorders, additional studies are needed to confirm these findings.

How to use: Take 300 to 680 mg of gotu kola extract 3 times per day for up to 14 days at a time.

According to a 2013 review, gotu kola can reduce the appearance of stretch marks. It’s thought that the terpenoids found in gotu kola increase collagen production in the body. This may help prevent new stretch marks from forming, as well as help heal any existing marks.

How to use: Apply a topical cream containing 1 percent gotu kola extract to the affected area several times per day.

How to do a skin patch test: It’s important to do a patch test before using any topical medication. To do this, rub a dime-sized amount on to the inside of your forearm. If you don’t experience any irritation or inflammation within 24 hours, it should be safe to use elsewhere.

Researchers in a 2015 study on rats found that wound dressing containing gotu kola had healing effects on multiple types of wounds. This includes clean cuts by sharp objects, irregular tears caused by blunt-force trauma, and infected tissue.

Although promising, further research is needed to confirm these findings.

How to use: Apply an ointment containing 1 percent gotu kola extract to the affected area several times per day. If your wound is deep or otherwise severe, see your doctor before use.

How to do a skin patch test: It’s important to do a patch test before using any topical medication. To do this, rub a dime-sized amount on to the inside of your forearm. If you don’t experience any irritation or inflammation within 24 hours, it should be safe to use elsewhere.

The anti-inflammatory properties of gotu kola may be useful in treating arthritis.

In fact, one 2014 study on collagen-induced arthritis in rats found that oral administration of gotu kola reduced joint inflammation, cartilage erosion, and bone erosion. Its antioxidant effect also had a positive effect on the immune system.

How to use: Take 300 to 680 mg of gotu kola extract 3 times per day for up to 14 days at a time.

Newer research is taking a look at gotu kola’s effect on liver and kidney toxicity.

According to one 2017 animal study, gotu kola can be used to suppress the toxic side effects of the antibiotic isoniazid. Isoniazid is used to treat and prevent tuberculosis.

Rats were given 100 mg of gotu kola for 30 days before they were given the antibiotic. These rats experienced less toxicity overall. Rats that did experience toxicity in the liver and kidneys resumed to near-normal levels after being given gotu kola.

More research is needed to expand upon these findings.

How to use: Take 30 to 60 drops of liquid gotu kola extract 3 times per day for up to 14 days at a time. Dosages may vary between manufacturers, so always carefully follow the directions on the bottle.

Gotu kola is generally well tolerated. In some cases, it can cause headache, upset stomach, and dizziness. Starting with a low dose and gradually working up to a full dose can help reduce your risk of side effects.

You should only take gotu kola for two to six weeks at a time. Be sure to take a two week break before resuming use.

When applied topically, gotu kola has the potential to cause skin irritation. You should always do a patch test before moving forward with a full application. Herbs aren’t monitored by the FDA and gotu kola has been found to have dangerous levels of heavy metals due to being grown in contaminated soil. Choose to buy products from reliable sources.

Don’t use gotu kola if you:

• are pregnant
• are breastfeeding
• have hepatitis or other liver disease
• have a scheduled surgery within the next two weeks
• are under 18 years of age
• have a history of skin cancer

Talk to your doctor before use if you:

• have liver disease
• have diabetes
• have high cholesterol
• are taking medications such as sedatives for sleep or anxiety
• are taking diuretics

Although gotu kola is generally considered safe to use, you should still check in with your doctor before use. This herbal remedy isn’t meant to replace any doctor-approved treatment plan, and, in some cases, it may lead to adverse side effects.

With your doctor’s approval, work an oral or topical dose into your daily routine. You may be able to avoid mild side effects by starting with a small amount and gradually increasing the dosage over time.

If you begin experiencing any unusual or prolonged side effects, discontinue use and see your doctor.

Gotu Kola (Centella asiatica) to protect our intellect

Gotu Kola (Centella asiatica, or shieldwort) is a creeping herbaceous perennial from the Umbelliferae family. Gotu grows wild in India, Indonesia, Malaysia and Sri Lanka, as well as in Iran and Northern Australia.

Centella Asiatica is grown for three months and harvested by hand. Its scientific name is Hydrocotile Asiatica. The first information about the plant comes from India. In traditional Chinese medicine, as well as in Indian Ayurvedic practice, Gotu Kola is used to prevent and treat memory disorders, anxiety, depression, and sleep disorders. Hindus and Chinese also believe that Gotu helps to increase life expectancy.

Gotu kola is often confused with the coca nut (Cola nitida), a caffeinated member of the cocoa family used to flavor cola soft drinks. Because the names are so similar, gotu kola is often thought to be related to the kola nut, but this is not the case. Gotu kola is sometimes added to energy drinks, reinforcing the false belief that it is a source of caffeine and an energy booster when in fact it is a decaffeinated relaxant.

Today, Gotu Kola is used in Western herbal pharmacotherapy, not only to improve cognitive function, but also as a prevention and treatment of venous diseases (eg, varicose veins and chronic venous insufficiency), as well as headaches. And a recent Japanese study in 2013 hypothesized that Gotu Kola contains saponins that can stop the growth of cancer cells.

How it affects the body

Gotu kola has impressive antioxidant, anti-inflammatory, antimicrobial and healing effects. It can be used externally to treat hemorrhoids, dislocations, dermatitis and cellulite. Some physicians even recognize its extremely curative effect for the treatment of leprosy. But the most significant benefits patients receive from the internal use of Gotu Kola. It is great for people with stomach ulcers, anemia, bronchitis, hypertension, dysentery.

It fights infections in the mouth and may prevent the formation of cancerous tumors. It is suitable for treating circulatory problems such as phlebitis, restless leg syndrome and varicose veins. Gotu kola strengthens blood vessels and gives elasticity to the arterial walls. It is also recommended for people with severe anxiety attacks and nervousness. It improves brain function, helping to concentrate and strengthening memory.

Due to its ability to form collagen fibers and elastin, it can be used to treat ulcers, burns and wounds (it is also suitable for accelerating the healing of scars after surgery), reducing wrinkles and stretch marks. Gotu kola is a wonderful assistant in the care of healthy hair and nails. It also has a beneficial effect on the condition of the scalp, especially in the presence of dandruff.

The plant helps to remove toxic and harmful substances that accumulate in the body. For this reason, scientists consider gotu kola to be a powerful diuretic that helps people who are overweight. It is also recommended for those with fluid retention or those suffering from kidney disease. Centella Asiatica is useful for women who suffer from severe and pronounced premenstrual syndrome, as well as those who feel constant fatigue due to daily activities.

The best way to support the brain

Gotu kola activates the release of neurotrophic factor (BDNF) in the brain, which acts as a fertilizer, stimulating the formation of new brain cells. To appreciate the effects of taking gotu kola, several weeks of daily use are needed. During this time, patients notice an increase in brain plasticity and facilitating communication between its cells. Thyroid boosts Nerve Growth Factor (NGF), which stimulates the growth of new nerve cells and protects existing ones.

If you are one of the millions of people struggling with stress, anxiety or depression, gotu kola can help. Research shows that gotu kola increases levels of neurotransmitters that make us feel good – serotonin, dopamine, and norepinephrine – while lowering levels of the stress hormone cortisol. By balancing these chemicals in the brain, gotu kola can help relieve stress, anxiety, and depression. In addition, it protects the brain from inflammation. It is believed that chronic brain inflammation is the main cause of depression. In human studies, the dietary supplement has shown an increase in life satisfaction, a state of rest and a 100% reduction in alertness, i.e. significantly reduced the symptoms of anxiety and depression.

The Journal of Alzheimer’s Disease has been researching the ability of gotu kola to improve memory at the molecular level. Its ability to enhance the activity of parts of the brain associated with the formation of long-term memory has been repeatedly documented. After testing the supplement in animals, specifically rats, Centella asiatica extract was found to improve learning and memory capacity by increasing blood levels of antioxidants. It also stimulates the cognitive function of the brain and improves memory in older subjects.

A separate study to enhance the cognitive effects of an aqueous extract of gotu kola was performed in mice. Although both young and old mice showed improvement in learning and memory using the Morris water maze, the effect was more pronounced in older mice. Also in laboratory studies, the existence of the effect of gotu kola on the protection of brain cells from toxic substances has been proven. This effect could potentially protect brain cells from plaque formation, which is associated with the development of Alzheimer’s. However, further research is needed to determine exactly how gotu kola can be used to treat Alzheimer’s disease.

Gotu kola can be considered a sedative, reduces anxiety and helps relieve stress. Some studies have found that centella helps in the treatment of depression by calming the nerves and even showing a hypnotic effect and improving the quality of sleep. A number of animal studies also confirm that this plant reduces anxiety and has an antidepressant effect.

A study published in the Journal of Ethnopharmacology came to similar conclusions, showing that older subjects who received centella asiatica supplements experienced improved mood and memory.

Some more benefits of Gotu Kola

Due to its antioxidant properties, gotu kola helps to strengthen tissues, in particular skin cells. It improves the condition of the upper layer of the epithelium, promotes rapid healing of wounds and enhances regeneration processes. Destruction of free radicals, helps to reduce the intensity of their accumulation, prevents premature aging of the skin and the appearance of oxidative damage.

Test animals treated with Centella asiatica directly on the wound, twice daily, had increased levels of antioxidants and accelerated healing. With prolonged use of the product, at least for 24 weeks, scientists noted an increase in collagen production by the skin. Thanks to this, the regeneration processes were significantly improved. Due to the regenerative properties of Centella asiatica, it is often used topically for skin conditions such as psoriasis and eczema.

Gotu kola also contains a chemical called triterpene fraction (TTFCA). TTFCA is especially helpful for varicose veins as it stimulates the production of collagen and elastin. These connective tissues are necessary to strengthen the inner lining and walls of blood vessels. Collagen and elastin are also elements of healthy skin that we lose with age. These factors indicate that gotu kola helps your skin look healthier. However, its effectiveness in the treatment of varicose veins is still a controversial issue that requires additional research.

Centella asiatica can help with venous insufficiency by reducing swelling and improving blood flow. Venous insufficiency is a medical condition in which your blood does not flow properly. This may be due to a complication of the upward movement of blood by damaged vessels, or a decrease in the general blood circulation due to cholesterol plaques. This state of the body often provokes varicose veins, which over time can lead to the appearance of vascular networks.

Gotu kola’s anti-inflammatory properties may also be helpful in the treatment of arthritis. In 2014, a study was conducted on rats, which revealed that the introduction of the extract reduces inflammation of the joints, erosion of cartilage and bones. Due to its antioxidant effect, gotu kola also showed a positive effect on the immune system of test subjects. A study in people with scleroderma found that gotu kola reduced joint pain, skin indurations, and improved finger movement.

When the blood vessels lose their elasticity, bloody effusions form in the legs and an increase in the general level of fluid. Because of this, the legs swell and venous insufficiency occurs. Several small studies have shown that gotu kola can help reduce swelling and improve circulation. In a study of 94 people with venous insufficiency, patients showed improvement after taking gotu kola compared to those who took a placebo.

Side effects and contraindications

Gotu kola is generally well tolerated. In some cases, its long-term use can cause headaches, indigestion, and dizziness. Starting with a low dose and gradually increasing it to the required one can significantly reduce the risk of side effects.

Gotu kola should be taken for two to six weeks. With longer use, it can accumulate in the body and cause a number of adverse effects. Be sure to take a break before repeating a course of at least two weeks.

Topical application of gotu kola may cause skin irritation. You should always do a sensitivity test by applying a small amount to an area of ​​skin and waiting for the result before fully using the herbal extract. Dangerous levels of heavy metals can be detected in gotu kola through cultivation in contaminated soil. Use products only from reliable sources.

Do not use gotu kola if:

• you are pregnant
• You are breastfeeding
• You have hepatitis or other liver disease
• You plan to have surgery within the next two weeks
• You are under 18 years of age
• You have skin cancer

Consult your doctor before use if:

• Do you have liver disease
• you are diabetic
• you have high cholesterol
• you take sleep or anxiety sedatives
• you take diuretics

Side effects from gotu kola are very rare, but they can still include skin allergies and itching when applied topically, and headache, upset stomach, nausea, dizziness, and extreme sleepiness when applied topically. This usually happens when taking too high doses.

Dosage and method of administration

Few herbal remedies can easily be added to your daily diet because, frankly, they don’t taste very good. But this does not apply to gotu kola. This plant has a mild taste, pleasant texture and attractive appearance. It’s almost watercress or parsley. Gotu kola is a common ingredient in many Asian cuisines. It is added to salads, rice and curry dishes. You won’t find gotu kola at your local grocery store here, but you can purchase seeds and grow your own if you live in a warm, humid climate.

The standard dose of gotu kola (Centella asiatica) differs depending on what you are using it for. Your doctor can help you find the right dose. Most studies use the following dosages:

Dried herb: dried leaf tea (a few grams or a teaspoon) can be consumed 3 times a day.

Herb powder: is available in capsules, used up to three times a day depending on dosage.

Tincture: 30 – 60 drops (equivalent to 1.5 – 3 ml) 3 times a day.

Standardized extract: 50 to 250 mg 2-3 times a day.

Standardized extracts should contain 40% Asiaticoside, 29-30% Asiatic acid, 29-30% Macacic acid and 1-2% Macacasoside.

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Gotu kola ᐈ What is it, benefits and harms, instruction, contraindications.

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Contents

What is gotu kola?

• Benefits of Gotu Kola

Prevention and treatment of diseases

• Gotu kola extract for the nervous system
• Brain health
• Cardiovascular system
• Gotu kola benefits for insomnia
• Skin condition
• Detoxification
• Gotu kola extract for joints
• Prevention and treatment of oncology

Gotu kola manual

• How to take gotu kola?

Safety gotu kola

• Side effects
• Contraindications

Terminals

Sources

Benefits of gotu kola for humans

Gotu kola is a perennial plant that has long been used in traditional medicine due to its powerful healing properties, its extract helps speed up wound healing, improve cognitive function and lower blood pressure. And this is not all the useful qualities of such a healing bush.

Numerous scientific studies have shown that Gotu Kola contains unique compounds such as triterpenoid saponins. Scientists are confident that it is that they are largely responsible for the medicinal properties of this plant and its impact on human health. But to confirm this information, additional tests are being carried out.

Alternative medicine practitioners have successfully used gotu kola in the treatment of:

1. wounds and certain dermatological diseases
2. diarrhea
3. reduced energy and loss of vitality
4. potency disorders
5. venereal diseases
6. menstrual irregularities
7. Hansen’s disease (leprosy)

In Ayurvedic and Traditional Chinese Medicine Gotu kola is widely used for anti-aging and life extension. Practitioners also claim that its extract is able to increase mental capacity, improve liver and kidney health.

It is worth noting that, to date, scientists do not have enough clinical data to confirm the effectiveness of such a plant for many of the conditions listed above . But at the same time, many properties of gotu kola are indeed scientifically confirmed (1).

Gotu kola extract for nervous system health

Gotu kola is widely used as a natural antidepressant and anxiolytic (anxiety medicine). Scientists have found that the effect of this plant on mood is due to its ability to regulate the activity of neurotransmitters (in particular, gamma-aminobutyric acid – GABA) in the human brain. This effect, according to most experts, gives such a component of the plant as asiatic acid. If classic anxiolytic drugs (GABA agonists) have a pronounced sedative effect and often cause drowsiness, then asiatic acid relieves anxiety without these side effects .

Several animal experiments have confirmed that gotu kola extract helps to calm down male mice that have been deprived of sleep for three days (2). As you know, lack of sleep negatively affects well-being, causes increased anxiety, oxidative damage and neuroinflammation. Gotu kola helps to neutralize such symptoms.

Another trial confirmed that mice given the extract for 5 days prior to sleep deprivation exhibited much less anxious behavior . They also had significantly improved locomotor activity and decreased oxidative damage. The plant extract also helped reduce some of the physical symptoms of behavioral depression in rats.

The unique antidepressant and anxiolytic properties of gotu kola have also been confirmed in human studies, in particular, a trial conducted among patients in a British hospital showed that it is the plant helps to improve people’s response to startle .

And an experiment among 33 patients diagnosed with generalized anxiety disorder showed that the use of gotu kola as a replacement for antidepressants after 60 days helped to significantly reduce the severity of stress, anxiety and depression.

Therefore, supplements with such an active ingredient can be a reliable assistant in maintaining a healthy psychological state. And every person who is worried about increased anxiety or depressed mood can experience the benefits of using them for themselves . Modern dietary supplements contain exclusively environmentally friendly natural raw materials and are well tolerated by the body without causing unwanted side effects.

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Brain Health Benefits of Gotu Kola

Gotu Kola’s antioxidant properties, as well as its ability to influence neurotransmitter activity, make this plant potentially effective in the prevention and treatment of cognitive impairment . And such properties have been confirmed by scientists.

A small clinical study looking at the effects of gotu kola extract and vitamin B9 (folic acid) after stroke found that taking 0.75-1 g of gotu kola or 3 mg of vitamin B9 per day has a positive effect on brain function, in particular on general cognition (3). At the same time, it was found that gotu kola is more effective for stimulating memory processes.

An experiment on rats showed that taking an aqueous extract of this plant improved learning and memory in both old and young animals. But in older animals, this effect was more pronounced.

READ ALSO: The best natural remedies for memory in the article:
Substances and drugs to improve memory and brain function

At the same time, one human study showed that gotu kola extract supplementation did a good job of improving alertness. And several laboratory experiments have confirmed that the extract based on this plant protects brain cells well from toxicity. This may reduce the risk of amyloid plaque formation, which is associated with Alzheimer’s disease.

Therefore, already now, every person who wants to improve the functioning of his brain and reduce the risk of cognitive impairment and severe neurodegenerative diseases can evaluate the benefits of dietary supplements with such a plant in his own practice.

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Cardiovascular Benefits of Gotu Kola

People who occasionally travel long distances by air are well aware of how much discomfort such flights can cause even in full health, including circulatory disorders, swelling, pain in the ankles and others unpleasant symptoms. Scientists have found that gotu kola can help prevent these conditions . An experiment among participants with varicose veins (such people are especially affected by long flights) showed that taking gotu kola extract two days before the flight, on the day of departure, and also on the next day after it significantly reduces the severity of unpleasant symptoms (4).

Also, several studies have confirmed that gotu kola improves the condition of the connective tissue of blood vessels . This makes it useful for the treatment of varicose veins and venous insufficiency. In one study among participants with severe venous hypertension, it was found that taking gotu kola daily for 8 weeks significantly improved the condition of the veins.

There is some evidence that Gotu kola helps patients with chronic venous insufficiency (CVI) by improving their blood circulation and promoting overall well-being. With this disease, the walls and / or valves of the veins of the lower extremities work inefficiently, which makes it difficult for the reverse flow of venous blood to the heart. Taking gotu kola helps to significantly alleviate the symptoms of chronic venous insufficiency, including heaviness in the legs, soreness and swelling.

Scientists suggest that this effect is associated with the action of triterpenes of this plant, which stimulate the production of cardiac glycosides . Cardiac glycosides, in turn, are organic compounds, they are able to increase the strength of the heart and increase the rate of heart contractions.

READ ALSO: About the most important nutrients for the heart and blood vessels in the article:
Vitamins for the heart

But the benefits of Gotu Kola for the cardiovascular system do not end there. Such a plant is also able to:

1. stabilize fatty plaques in blood vessels, which helps to avoid their rupture and the development of a heart attack or stroke
2. normalize blood pressure in hypertension
3. to reduce the risk of diabetic microangiopathy – a complication of diabetes mellitus, the further progression of which can lead to various serious conditions, incl. blindness, heart failure, gangrene

It is safe to use gotu kola supplements for varicose veins or CVI . Modern manufacturers offer a wide range of dietary supplements on a natural basis. Such drugs are well tolerated, rarely cause side effects, act gently and give a positive effect for a long time.

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How does gotu kola extract work for insomnia?

Since gotu kola is indeed effective in reducing anxiety, stress and depression, it can also be used to combat insomnia that often accompanies such conditions (5).

Many researchers believe that extracts based on this plant are a safe alternative to prescription drugs , while herbal supplements work just as effectively, but more gently and do not cause unwanted side effects, including addiction.

How does gotu kola affect the skin?

The antioxidant properties of gotu kola make it a good anti-aging agent, but scientists have also shown that extract of this plant can prevent the shortening of telomeres (a series of DNA sequences at the end of the chromosome) that is correlated with aging.

Therefore, both internal supplementation with gotu kola and topical application of products with its extract contribute to:

1. tightening loose skin
2. prevention of early wrinkles
3. to eliminate existing wrinkles

Gotu kola topicals also have powerful anti-inflammatory properties and stimulate regenerative processes. Scientists have confirmed their effectiveness in skin rashes (including eczema and psoriasis). In trials, gotu kola ointment was found to help speed up the healing of wounds, including cuts and infected tissues (6). It also reduces the risk of stretch marks.

READ ALSO: About the most important vitamins and minerals for skin health in the article:
Vitamins for hair, skin and nails myth or reality?

Gotu kola for detoxification of the body

Studies have shown that gotu kola can be used as a means to combat intoxication of the body , including after taking certain medications. In particular, one animal study found that taking gotu kola for a month before antibiotic therapy helped almost completely neutralize the negative effect of antibiotics on the liver and kidneys (7). Also, similar results were obtained when taking the extract of this plant after antibiotic therapy.

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Gotu kola benefits for joint pain

Gotu kola can help relieve joint pain. It has a good anti-inflammatory effect, which according to many experts makes it potentially useful for the treatment of arthritis . Such properties of a unique plant have been confirmed during several studies.

One experiment in rats with arthritis showed that oral administration of Gotu Kola extract reduced joint inflammation, inhibited erosive processes in cartilage and bone tissue (8). Also, the individuals showed a significant improvement in the functioning of the immune system.

Therefore, gotu kola supplements for arthritis can indeed be of great benefit and even replace some of the standard medications that cause a lot of side effects. Dietary supplements with an extract of such a medicinal plant act gently and are well tolerated by the body.

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Gotu Kola for Cancer Prevention and Treatment

Gotu Kola is known to have powerful antioxidant properties. It effectively neutralizes many free radicals, the excess of which increases the risk of cancer. Studies have confirmed that such properties of this plant can increase the body’s defense against oncology (1).

It also turned out that asiatic acid is able to induce apoptosis (natural cell death) and inhibit the growth of certain cancer cells, incl. cancer of the liver, breast, skin, brain and digestive tract.

How to take gotu kola?

To date, scientists have not yet determined the optimal dosage options for gotu kola extract – more research is being done for this. Nevertheless, according to the results of previous experiments to combat anxiety, you need to take 500 mg of this remedy twice a day. And in the treatment of depression, it is worth slightly increasing the dosage – up to 750 mg twice a day. If necessary, the dosage may be changed.

Numerous experiments confirm that dose of 2-4 g of gotu kola extract is absolutely safe for humans. Most scientists recommend that you still follow the recommendations on the packaging of a particular drug.

Gotu kola extract course should not exceed 2-6 weeks , and you can resume taking only after a two-week break.

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Side effects of gotu kola

Gotu kola is generally well tolerated. Only occasionally an extract of this plant may cause some side effects:

1. headache
2. diarrhea
3. dizziness

To avoid side effects, experts recommend starting with small doses of and then gradually increasing the dosage to full.

Contraindications

Gotu kola contraindications include:

1

pregnancy

2

breast-feeding

3

hepatitis and other liver diseases

4

planning for surgery in the next 2 weeks

5

childhood

6

a history of skin cancer

It is important for some people to consult a doctor before taking gotu kola supplements. This applies to persons who:

1

have liver disease

2

suffer from diabetes

3

have high cholesterol levels

4

are taking sedatives, anxiolytics, antidepressants, or diuretics

On our website you can get a free consultation from a pharmacist who will help you understand the peculiarities of dosing and supplementing with gotu kola. A qualified specialist with specialized education will answer your questions absolutely free of charge.

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Conclusions

Gotu kola is an extract of the medicinal plant of the same name, which is used as a antioxidant, anti-inflammatory and anti-anxiety agent. It has long been used in Ayurvedic medicine, but over time, the properties of such a plant have been confirmed at the scientific level.

Gotu kola supports nervous system health and can be used to treat anxiety and depression. It helps to calm down and pull yourself together, neutralizes illogical fears and promotes a healthy night’s rest. Also, the extract of this plant has a positive effect on the functioning of the brain: it slows down the aging process, improves memorization and reduces the risk of developing Alzheimer’s disease and other neurodegenerative diseases.