What are the common side effects of Euflexxa shots. How is the procedure performed. What precautions should be taken before and after Euflexxa injections. When should you seek medical attention following hyaluronate injections.

Understanding Hyaluronate Injections for Knee Osteoarthritis

Hyaluronate injections, including brands like Euflexxa, Hymovis, and Orthovisc, are increasingly popular treatments for knee pain caused by osteoarthritis. These injections aim to provide relief when other osteoarthritis treatments have proven ineffective.

Osteoarthritis is a degenerative joint disease characterized by the breakdown of cartilage, the protective tissue at the ends of bones. This deterioration can lead to pain, swelling, and reduced mobility. Hyaluronate injections are designed to alleviate these symptoms by supplementing the joint’s natural lubricating fluid.

How do hyaluronate injections work?

Hyaluronate injections work by introducing a substance similar to the naturally occurring synovial fluid in your joints. This supplementation helps to:

• Improve joint lubrication
• Reduce inflammation
• Provide a cushioning effect
• Potentially stimulate the production of natural hyaluronic acid in the joint

Treatment schedule and duration of relief

The treatment regimen for hyaluronate injections typically involves:

• Weekly injections for 2 to 5 weeks, depending on the specific medication used
• Pain relief lasting from several weeks to a few months

Is hyaluronate treatment suitable for everyone with knee osteoarthritis. While many patients benefit from these injections, they are usually recommended when other treatments have not provided adequate relief. Your doctor will assess your individual case to determine if hyaluronate injections are appropriate for you.

Preparing for Your Euflexxa or Hyaluronate Injection

Proper preparation is crucial for ensuring the safety and effectiveness of your hyaluronate injection. Before your procedure, it’s essential to communicate openly with your healthcare provider about your medical history and current medications.

Important information to disclose to your doctor

Be sure to inform your doctor if you:

• Have any allergies, especially to latex or medications
• Are experiencing an infection near the knee joint where the injection will be administered
• Are currently undergoing chemotherapy
• Are taking blood-thinning medications or NSAIDs

Why is it important to disclose medication use before the procedure. Certain medications, particularly blood thinners and anti-inflammatory drugs, can increase the risk of bleeding or interfere with the effectiveness of the injection. Your doctor may advise you to temporarily discontinue or adjust the dosage of these medications before the procedure.

Medications that may affect your hyaluronate injection

Pay special attention to the following medications:

1. Aspirin and aspirin-containing products
2. Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) or naproxen (Aleve)
3. Anticoagulants like warfarin (Coumadin), clopidogrel (Plavix), or heparin
4. Novel oral anticoagulants (NOACs) including rivaroxaban (Xarelto), dabigatran (Pradaxa), and apixaban (Eliquis)

Should you stop all medications before the procedure. No, do not stop any prescribed medications without first consulting your doctor. They will provide specific instructions based on your individual health needs and the requirements of the hyaluronate injection procedure.

The Hyaluronate Injection Procedure: What to Expect

Understanding the injection process can help alleviate anxiety and ensure you’re properly prepared for the procedure. Here’s a step-by-step breakdown of what typically occurs during a hyaluronate injection appointment.

Before the injection

Prior to receiving your first hyaluronate injection, you will need to:

• Sign a consent form acknowledging that you understand the procedure and its potential risks
• Undergo a brief examination of your knee joint
• Possibly have an ultrasound to determine the precise injection site

During the injection

The injection process usually involves the following steps:

1. Cleaning of the injection site
2. Possible administration of local anesthesia
3. Insertion of the needle and injection of the hyaluronate medication
4. Removal of the needle and application of a small bandage

Is the hyaluronate injection painful. Most patients report only mild discomfort during the procedure, typically described as a pinching sensation when the needle enters the skin and when the medication is injected. The use of local anesthesia, when administered, can further minimize any potential pain.

Post-Injection Care and Recovery

Proper aftercare is crucial for maximizing the benefits of your hyaluronate injection and minimizing the risk of complications. Following your doctor’s post-procedure instructions carefully can help ensure a smooth recovery and optimal results.

Immediate post-injection care

In the first 24 hours after your injection:

• Keep the injection site dry and covered with a clean bandage
• Avoid baths, hot tubs, saunas, or swimming
• Do not apply hot or warm packs to the injection site
• Avoid applying creams or topical medications to the area

Managing discomfort and activity levels

To manage any post-injection discomfort and protect your knee:

• Use cold packs for 10-15 minutes every 4 hours if needed
• Take over-the-counter pain medication as recommended by your doctor
• Follow your doctor’s advice regarding activity restrictions
• Be aware that your knee may feel stiff or spongy for 2-3 days

How long does it take to feel the effects of the hyaluronate injection. The timing can vary among individuals, but many patients don’t experience significant pain relief until after completing their full series of injections. It’s important to be patient and maintain open communication with your healthcare provider about your progress.

Potential Side Effects and Complications of Euflexxa and Other Hyaluronate Injections

While hyaluronate injections are generally considered safe, it’s important to be aware of potential side effects and know when to seek medical attention. Most side effects, when they occur, are mild and resolve on their own.

Common side effects

The most frequently reported side effects include:

• Temporary pain or stiffness at the injection site
• Mild swelling or warmth around the knee
• Brief increase in joint pain

Rare but serious complications

Although uncommon, more serious reactions can occur, such as:

• Allergic reactions
• Infection at the injection site
• Severe inflammation
• Bleeding into the joint

Can hyaluronate injections cause long-term side effects. Long-term side effects from hyaluronate injections are extremely rare. However, as with any medical procedure, it’s important to discuss any concerns about potential long-term effects with your healthcare provider.

When to Seek Medical Attention After Hyaluronate Injections

While serious complications from hyaluronate injections are rare, it’s crucial to be vigilant and know when to seek medical help. Prompt attention to unusual symptoms can prevent potential complications from becoming more serious.

Emergency situations

Call 911 immediately if you experience:

• Signs of a severe allergic reaction (anaphylaxis), such as difficulty breathing, swelling of the face or throat, or a widespread rash
• Sudden, severe pain in the injected knee
• Loss of sensation or movement in the leg

Non-emergency concerns

Contact your doctor if you notice:

• Fever of 100.4°F (38.3°C) or higher
• Persistent pain at the injection site beyond 48 hours
• Increasing redness, swelling, or warmth around the knee
• Unusual bruising or discoloration
• Unexplained back or muscle pain
• Nausea or skin irritation
• Any new or unexplained symptoms

How quickly should you expect a response to your concerns. Your healthcare provider should have a system in place for addressing patient concerns. If you’re experiencing worrying symptoms, don’t hesitate to reach out. Many practices offer after-hours contact options for urgent issues.

Maximizing the Benefits of Your Hyaluronate Treatment

While hyaluronate injections can provide significant relief from osteoarthritis pain, there are steps you can take to enhance and prolong the benefits of your treatment. Combining these injections with other osteoarthritis management strategies can lead to better overall outcomes.

Complementary treatments and lifestyle changes

Consider incorporating the following into your osteoarthritis management plan:

• Physical therapy to improve joint strength and flexibility
• Low-impact exercises like swimming or cycling
• Weight management to reduce stress on your knees
• Use of assistive devices when necessary
• Application of hot or cold therapy as recommended by your doctor

Follow-up care and monitoring

To ensure ongoing success with your treatment:

• Attend all scheduled follow-up appointments
• Keep a pain diary to track your symptoms and improvements
• Discuss any changes in your condition with your healthcare provider
• Be open to adjustments in your treatment plan as needed

How often should you receive hyaluronate injections. The frequency of injections can vary depending on individual response and the specific product used. Some patients may benefit from repeat treatments every 6 months, while others may have longer-lasting relief. Your doctor will work with you to determine the optimal treatment schedule based on your unique needs and response to the injections.

By following these guidelines and maintaining open communication with your healthcare team, you can maximize the benefits of your hyaluronate injections and improve your overall quality of life while managing knee osteoarthritis. Remember that everyone’s experience with osteoarthritis and its treatments is unique, so it’s important to work closely with your doctor to develop a personalized approach that works best for you.

About Hyaluronate Injections in Your Knee

Time to Read:
About 2 minutes

This information explains what to expect after your hyaluronate (Hymovis^®, Orthovisc^®, Euflexxa^®) injections (shots) in your knee.

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About Hyaluronate Injections

Hyaluronate is a medication that’s used to treat knee pain caused by osteoarthritis. Osteoarthritis is a disease in which the cartilage (protective tissue at the ends of bones) of your joint wears down. This can lead to pain and swelling.

Hyaluronate is used when you still have pain after trying other treatments for osteoarthritis. This medication is injected into your joint and should help with the pain when you move.

Most people get the injections once a week for 2 to 5 weeks in a row, depending on which medication your doctor is using. The pain relief from hyaluronate injections may last from several weeks to a few months.

For more information about your injection, ask your nurse for the resource Hyaluronate and Derivatives.

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Before Your Procedure

Before your injection, tell your doctor if you:

• Have an allergy to latex or any medications.
• Have an infection near your knee joint where the injection will be given.
• Are currently receiving chemotherapy.
• Are taking any of the following medications:
  • Aspirin or medications that contain aspirin
  • Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil®, Motrin®) or naproxen (Aleve®)
  • Medications that prevent blood clots, such as warfarin (Coumadin®), clopidogrel (Plavix®), enoxaparin (Lovenox®), rivaroxaban (Xarelto®), dabigatran (Pradaxa®), apixaban (Eliquis®), or heparin

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During Your Procedure

The first time you get your hyaluronate injection, you will need to sign a consent form (form that says you agree to the procedure and understand the risks).

Your doctor may do an ultrasound (imaging that uses sound waves to make a picture) to decide where to do the injection.  Your doctor will examine your joint and clean the area. Some people may get an injection of local anesthesia (medication that numbs an area) before getting the hyaluronate injection.

During your hyaluronate injection, you should only feel some pinching as the needle is put through your skin and the medication is injected. After the medication is injected, your doctor will remove the needle and clean the injection site. You will have a small bandage (Band-aid^®) placed over the site.

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After Your Procedure

• Follow these guidelines after your procedure.
• Keep the injection site dry and keep a clean bandage over the site for 24 hours.
• Don’t take a bath, use a hot tub or sauna, go swimming, or submerge yourself in water for 2 days after your procedure.
• The site may be sore for a few days. Ask your doctor about taking pain medication.
• Ask your doctor if there are any activities or movements that you should avoid, such as standing for long periods, jogging, or lifting heavy objects.
• Don’t use hot or warm packs on the site for 24 hours after your injection.
• Your knee may feel stiff or you may feel a spongy sensation when you walk. This may last for 2 to 3 days.
• You may not feel relief from your knee pain until after your last injection.
• You may apply a cold pack to your knee for 10 to 15 minutes every 4 hours to help with any discomfort.
• After your injection, you may take your usual prescription or over-the-counter (medications you buy without a prescription) pain medication (such as Advil, Aleve, or Tylenol®) to help with any pain you’re feeling. 
• Don’t put on any creams or topical medications (medications you put on your skin) to the injection site for 24 hours.

Side effects

Side effects are rare. Your knee may feel slightly tender or stiff following the injection. Most people don’t have any other reaction to their hyaluronate injection.

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Call 911 if You:

• Have any signs of an allergic reaction such as a rash, red, swollen, blistered, or peeling skin, difficulty breathing, or swelling in your mouth, face, lips or throat.

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Call Your Doctor or Nurse if You Have Any of the Following Signs of Infection:

• A fever of 100.4° F (38.3° C) or higher
• Pain at the injection site that doesn’t start to feel better after 48 hours
• Redness or swelling where the shot was given
• Bruising or discoloration where the shot was given
• Warmth in or by your knee
• Back pain
• Muscle pain
• Higher blood pressure than usual
• Nausea (feeling like you’re going to throw up)
• Skin irritation such as rash or itching.
• Any new or unexplained symptoms

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Last Updated

Thursday, December 19, 2019

What Is Euflexxa and How Does It Work?

Euflexxa is a brand of drug used to treat pain caused by knee osteoarthritis (OA). OA, also called “wear and tear” arthritis, is the most common and long-term degenerative joint condition that causes joint pain, stiffness, and swelling.  

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In OA, the strong fibrous tissue surrounding the ends of the bones (cartilage) breaks down or changes in structure resulting in symptoms such as pain, joint swelling, and stiffness.

A doctor may prescribe Euflexxa for patients whose pain is not relieved by simple pain medications, such as acetaminophen (Tylenol), or non-drug treatments, such as exercise and physical therapy.

Euflexxa contains the active drug sodium hyaluronate. Sodium hyaluronate is a thick gel-like substance naturally present in our joint tissue acting as the fluid between our joints. It lubricates the joint, absorbs shock during movement, and allows the joint to function properly. 

Other brands that contain sodium hyaluronate are:

• Durolane
• Synvisc
• Gel-One
• Hyalgan
• Hyalgan LL
• Supartz
• Supartz FX

How Is Euflexxa Supplied and Used?

Euflexxa comes in disposable, pre-filled glass syringes. Each syringe contains 2 ml of the product or 20 mg of the active drug. A doctor or other healthcare professional injects the product into the affected knee. 

How Does Euflexxa Work?

Euflexxa contains sodium hyaluronate, which helps joint pain by: 

• Increasing the amount of hyaluronic acid in the joint tissue and fluid
• Reducing inflammation in the affected knee
• Blocking sensitivity to pain stimulus
• Stimulating natural hyaluronic acid production 

What Are the Side Effects of Euflexxa?

Common Side Effects

• Feeling of warmth, pain, or redness at the injection site
• Nausea
• Stomach pain
• Loss of appetite
• Diarrhea
• Difficulty walking
• Swelling in your hands or feet
• Back pain
• Joint pain
• Muscle pain
• Numbness
• Headache
• Dizziness
• Runny or stuffy nose
• Sneezing
• Sore throat

Most patients do not experience any side effects, or if they do, the side effects are temporary and usually subside quickly after the injection. However, if a side effect does not go away after the injection, it is best to contact your healthcare provider immediately. 

Serious Side Effects

Contact your doctor immediately if any of the following side effects occur during treatment:

• Bluish discoloration or flushing 
• Cough
• Difficulty swallowing
• Severe dizziness
• Fever
• Persistent or worsening pain at the injection site
• Skin rash/hives with or without itching
• Swelling of eyelids, face, or lips
• Tightness in chest
• Difficulty breathing
• Wheezing
• Severe headache
• Pounding heartbeat

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Can This Medication Cause Severe Allergic Reactions?

A life-threatening allergic reaction to this drug is rare. However, seek immediate medical care if you notice the signs and symptoms of a serious allergic reaction, such as:

• Rash
• Hives
• Swelling of the face, tongue, or throat
• Severe itching
• Severe dizziness
• Breathing difficulty

Euflexxa Dosage

Your doctor or a healthcare professional will inject 2 ml of Euflexxa into the affected joint every week for three weeks total. 

What Should You Know Before Taking Euflexxa?

Patients should be advised to avoid taking this drug if they have a history of allergy to the product or other hyaluronic acid products. Furthermore, they should not receive the injection in case of a knee infection or skin infection around the knee. 

Please inform your doctor if you are pregnant or planning to become pregnant, as safety and efficacy have not been established in specific populations. Your doctor should also be informed if you are breastfeeding or younger than 18 years of age. 

What Should You Not Do After Taking Euflexxa?

• Avoid physical activities, such as jogging, tennis, and heavy lifting, for at least 48 hours after receiving the injection.
• Do not stand on your feet for more than 60 minutes without a break during the 48-hour period after taking this medication. 

What Should You Do After Taking Euflexxa?

• Ask your doctor when you can return to doing physical activities that require using your leg. 
• You may apply a cold pack to relieve mild pain or swelling near the injection site. 
• Call your doctor right away if you have severe joint pain, back pain, or muscle pain. 

How Long Will Euflexxa Relieve Pain?

After receiving all three injections, you can expect pain relief for about 6 months. However, results can and will be different for each patient.  For optimal benefits, you should get all the injections on time without delay. It is unknown if repeating treatment cycles for more than one year is safe. 

How Long Does It Take For Euflexxa to Work?

The time it takes for Euflexxa to work can vary. However, it is common for most users to start feeling better 2 weeks after the third injection. 

Can Pregnant Women Use This Medication?

Euflexxa has not been tested in pregnant patients, and it is unclear if this drug is safe and effective for use in pregnant women. Nonetheless, a doctor may prescribe it if the potential benefits clearly outweigh the risks. 

Can Breastfeeding Women Use This Medication?

It is unclear if this drug is safe and effective for use in breastfeeding women as it was not tested. Furthermore, researchers have yet to determine if Euflexxa passes into breast milk. Therefore, talk to your doctor before breastfeeding and starting Euflexxa.

Euflexxa vs. Corticosteroid Injection: Which Is Better?

Corticosteroid injections have been used to help manage joint pain for many years. While they help by reducing inflammation in the joints, injections such as Euflexxa consist of sodium hyaluronate, which acts as a lubricant for the joints providing better and longer pain-free periods. Both have comparable benefits in improving knee function. Nonetheless, according to a 2017 study, injectable corticosteroids may be more effective in the short term, while Euflexxa appears better for long-term pain relief [1].

Which Is the Cheapest Injectable Hyaluronate Brand?

A 2016 study compared the costs and benefits (in terms of quality of life) of different hyaluronic acid injection products: Euflexxa, Synvisc, Durolane, Hyalgan, and Supartz. 

It was found that Euflexxa had the lowest cost–utility ratio among all the five products, which indicates that Euflexxa users paid the lowest for improved quality of life.

Can You Use Euflexxa for Shoulder or Hip Pain Due to Osteoarthritis?

No. Euflexxa is only intended for use only in the knees.  

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Is the Injection Painful?

Pain, regardless of the type, is subjective. Yet, there are several ways to reduce injection pain. For instance, your doctor will likely use a numbing agent on the site of injection to reduce pain and discomfort. 

How Much Does Euflexxa Cost?

The amount you pay for the treatment can vary, depending on your insurance plan, geographical location, and pharmacy. Contact your insurance provider to find out if your plan covers this product or if you need prior authorization. 

REFERENCES:

1. He, Wei-wei et al. “Efficacy and safety of intraarticular hyaluronic acid and corticosteroid for knee osteoarthritis: A meta-analysis. ” International journal of surgery 39 (2017): 95-103.
2. Rosen, J., Sancheti, P., Fierlinger, A. et al. Cost-Effectiveness of Different Forms of Intra-Articular Injections for the Treatment of Osteoarthritis of the Knee. Adv Ther 33, 998–1011 (2016). https://doi.org/10.1007/s12325-016-0331-8

This information is not a substitute for medical advice or treatment. Talk to your doctor or healthcare provider about your medical condition prior to starting any new treatment. AmeriPharma Specialty Care assumes no liability whatsoever for the information provided or for any diagnosis or treatment made as a result, nor is it responsible for the reliability of the content.

AmeriPharma Specialty Care does not operate all the websites/organizations listed here, nor is it responsible for the availability or reliability of their content. These listings do not imply or constitute an endorsement, sponsorship, or recommendation by AmeriPharma Specialty Care.

This webpage may contain references to brand-name prescription drugs that are trademarks or registered trademarks of pharmaceutical manufacturers not affiliated with AmeriPharma Specialty Care.

Complications and side effects after fillers

Filler injections are a cosmetic procedure that successfully corrects the appearance. Fillers help to model the volume of the face, replenish tissues, smooth out wrinkles, creases, and even out the skin. Despite their effectiveness and safety, fillers can cause complications. This happens due to the individual characteristics of the body, the wrong dosage, the mistakes of doctors.

Fillers are widely used in cosmetology. Previously, fillers were less perfect, as they were developed on the basis of synthetic materials. such as silicone. Such drugs caused a lot of side effects, the most striking of which was the displacement of the filler in the tissues. He remained there literally forever and had to be removed by a rather painful surgical procedure with a long rehabilitation.

Modern cosmetology does not stand still and instead of outdated preparations, fillers based on hyaluronic acid have come, which is excreted over time and does not migrate in tissues. Fillers with hyaluron are unique. They help the skin look young and well-groomed. Their composition is quite safe and the main component is hyaluronic acid. It allows not only to eliminate aesthetic imperfections, but also helps to model harmonious features of the face and body. Used to correct the following zones:

• Lips;
• Nasolabial folds;
• Cheekbones and cheeks;
• Forehead;
• Eyelids and nasolacrimal groove;
• Nose;
• Chin;
• Scalp.

Filler injections are injection methods for skin rejuvenation. They are considered by medical experts to be quite safe. Moreover, in some cases they can become a fairly good alternative to plastic surgery, the minus of which is possible clinical complications and a fairly long rehabilitation. But the body of each person is individual and no one is immune from side effects. Such as allergic reactions, swelling in the injection area, redness, burning, soreness, hematomas, bruises, hyperemia. Some of the complications pass quickly and without a trace. For others, a long and thorough treatment is required.

Causes of complications after contouring

Very often, clinical complications appear due to insufficient qualifications of a medical specialist or due to the individual characteristics of the patient’s body. Many women want to save money and turn to rather dubious clinics that provide incompetent services. Uneducated cosmetologists can work there. Or the clinic uses cheap, non-certified drugs that can be harmful to health. Therefore, too low a price should definitely alert you. A good clinic will not offer their services too cheaply, nor will they save on fillers. The quality of cosmetic services in such establishments usually leaves much to be desired. Cheaper than the cost of the manufacturer can not cost a drug for contour plastics. Especially if it is officially certified.

Also, certain side effects may be associated with inadequate care during the rehabilitation period, when patients simply do not follow the recommendations of medical specialists. This happens if the injections were made in particularly delicate areas. For example, in the nasolabial fold or periorbital zone. There are individual body reactions that can lead to side effects. Such as allergies, so the beautician should conduct a consultation and take an anamnesis in advance before the procedure. Remember that filler injections for contouring are done only in beauty salons or clinics that are licensed to carry out medical activities. No normal certified cosmetologist will do this kind of procedure at home. And unprofessionalism is another reason for the appearance of side effects. They can be caused by drugs at a low price and from unverified manufacturers.

Common side effects after injections of fillers

The most common side effects in patients are of the following nature:

• Bruising at the injection site . They are painful. Appear in the injection area. With normal care, they pass in patients on their own without a trace. The risk of large bruises and hematomas increases when taking blood thinners, non-steroidal anti-inflammatory drugs, certain types of antibiotics, dietary supplements. This fact must be told to the beautician in advance;
• Edema formation . After the injection, edema often appears. This is a completely normal reaction of the body to intervention in it. In fillers, the main component is hyaluronic acid. It attracts water, so the first couple of days after injections, swelling will be noticeable;
• Tyndall effect . With it, a slight translucence of the filler is noted. The quality of the drug itself plays a role in the formation of a side effect. Cheap fillers of dubious origin often give this effect. The Tyndall effect is also noted when using hyaluronic fillers that are too dense in texture;
• Pain sensations i. Another individual reaction of the human body to drug injections. Cosmetologists use special creams or gels with anesthetic components to relieve pain.

In some cases, patients may experience sensory impairment due to nerve compression by the filler. If such a symptom occurs, you should immediately consult a doctor for medical attention. Phenomena such as pain, bruising, bruising, swelling disappear after a couple of days.

Allergy to fillers

Allergic reactions are quite common side effects experienced by patients. They appear for the following reasons:

• Tendency to form allergies. There are people who overreact to literally any possible allergen;
• Reaction to anesthetic creams and gels used for pain relief;
• Intolerance to hyaluronic acid fillers. This is especially true for drugs with artificial non-natural fillers;
• Allergy to additional drugs included in fillers. These can be vitamins, amino acids, peptides;
• Presence of contraindications for contouring.

Symptoms vary by treatment area. For example, with injection lip augmentation, swelling, redness, and discomfort appear at the injection site of the filter. There are symptoms that indicate that you should immediately go to the doctor for medical help:

• Severe swelling that does not go away after a couple of days, but only intensifies with time;
• Herpes growth;
• Discoloration of the skin in the treatment area;
• Appearance of characteristic pigmentation;
• Severe burning and itching at the injection site;
• Eruptions on the skin.

First aid is the use of antihistamines, which temporarily relieve allergy symptoms. After that, you need to see a doctor.

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More dangerous complications from fillers

After injections of hyaluronic acid, more serious side effects can occur that threaten the patient’s health. Such as:

• The formation of severe inflammation, in which there is an increase in temperature, swelling, redness of the skin;
• Infection in soft tissues
• Granulomas. They appear during the rejection of fillers by the patient’s body. They look like small dense nodules on the surface of the skin;
• Filler displacement due to high density or incorrect distribution. Also, the drug is displaced if the injection was made close to the surface of the skin;
• Embolism. A serious side effect in which there is a blockage of the vessel by the drug. This can lead to tissue necrosis;
• Ischemia. With ischemia, the blood supply to the soft tissues is suppressed. As well as embolism can lead to tissue necrosis;
• Violation of nerve conduction in the area of ​​injection of a filler with hyaluronic acid.

It is important to note that even an experienced and qualified beautician is not completely immune from such cases.

How to minimize the risks of side effects?

Complications can be avoided if possible. And you need to pay attention to the following factors:

• Clinic. The medical organization must have a license and reviews. The longer the clinic operates, the more trust it should have;
• Specialists. Remember that a competent cosmetologist will never perform contouring with fillers at home. All manipulations are done only in the cosmetologist’s office. The doctor himself must have the appropriate education and skills;
• Explore clinics in detail, from job documents to customer reviews of the organization. After all, you trust doctors, first of all, your health;
• At the first consultation, you can ask for documents and certificates for preparations with hyaluronic acid;
• Find out more about possible contraindications and side effects during the consultation. If you have allergic reactions, then talk about them;
• See how thorough and detailed the initial consultation is. The cosmetologist is obliged to conduct an examination, collect a complete patient history in order to identify possible contraindications to hyaluronic acid filler injections. The medicinal product should be selected by the medical specialist taking into account the patient’s problem, anatomical features, type of aging, contraindications and indications for use.

You can minimize the risk of side effects if you pay attention to the choice of drugs. The safest fillers are approved by the FDA. And only doctors with a higher medical education can administer them to patients.

Frequently Asked Questions

What are the types of fillers and how do they differ?

Fillers with hyaluronic acid differ in biologically active composition, duration of therapeutic effect, substance density. Now cosmetologists mainly use such popular and safe fillers as Belotero, Juvederm, Restylane, Radiesse, Elevess, Sculptra and others.

Does it hurt to get fillers?

Everyone’s pain threshold is different. But cosmetologists use modern application anesthesia in the form of a cream or gel to minimize possible pain. There are dermal fillers that already contain such an anesthetic component as Lidocaine.

How long does the effect of fillers last?

It all depends on which preparation was chosen by the beautician. The brand of the filler, its manufacturer, how the patient complies with the rules of rehabilitation care, where the drug was localized, and the individual characteristics of the patient have an impact.

When should fillers not be injected?

Plastic surgery with hyaluronic acid preparations is contraindicated in patients under the age of eighteen, during pregnancy and breastfeeding, pathologies of hematopoietic functions, exacerbation of the herpes virus, malignant neoplasms, acute respiratory infections, abrasions, burns, cuts in the area of ​​drug administration.

How do you know if there are complications from a filler injection?

Usually swelling, bruising, redness of the skin disappear without a trace after a couple of days after the injection of preparations with hyaluronic acid. If you have experienced severe swelling, itching, irritation, redness, extensive bruising for more than a week, then you should urgently contact medical specialists. If an allergic reaction is suspected, the first step is to take an antihistamine drug. And then also turn to the doctor for help. During the rehabilitation period, it is necessary to strictly follow all the recommendations of the doctor in order to avoid possible side effects. This way you can avoid them.

Photos of complications after contouring

Elena Ilchuk

Dermatologist-cosmetologist, Candidate of Medical Sciences, Chief Physician of the “Elevans” clinic, over 17 years of experience.

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Frequently Asked Questions

Euflexxa is an effective remedy for knee pain caused by osteoarthritis. Physicians or licensed healthcare professionals, as well as hospitals and clinics, can purchase Euflexxa online at MedicaDepot.com. In addition, this drug can also be ordered by phone, contacting our support specialists to help patients feel as good as possible in the shortest possible time.

3 pre-filled 2 ml syringes Package leaflet

Euflexxa is an injectable gliding agent used to relieve pain caused by osteoarthritis of the knee. Euflexxa is made from hyaluronic acid, a natural substance found in the synovial fluid of the knee joint. Usually, side effects associated with the use of this drug are mild and include pain and irritation at the injection site, swelling, bruising, warmth in the knee, and headache.

As the patient ages, or when the knee is stressed due to excess weight or physical activity, cartilage begins to break down and the amount of synovial fluid decreases. Without this protection, the patient’s knee bones begin to rub against each other. This causes inflammation, irritation and pain. After the introduction of Euflex (Euflexxa) into the patient’s knee, the drug replaces the synovial fluid, which has become less in the joint, lubricates the knee and softens the movement. This allows the patient to walk without feeling the friction of the bones and restore mobility.

Sodium hyaluronate (10 mg/ml), sodium chloride (8.5 mg/ml), sodium hydrogen phosphate dodecahydrate (0.56 mg/ml), sodium dihydrogen phosphate dihydrate (0. 05 mg/ml). Instructions for use How to administer this product This medical product is approved for use only by qualified physicians. Remove all joint effusion. Connect a suitable size needle (17-21G) to the syringe according to the manufacturer’s instructions. Inject the entire contents of the syringe into the joint (synovial capsule of the knee) according to the aseptic insertion procedure.

Euflexxa is designed to relieve knee pain caused by osteoarthritis.

Some patients report a reduction in pain after the first injection of Euflexxa, but in some cases the symptoms of osteoarthritis are relieved only after all three injections. In any case, the patient is recommended to undergo 3 treatments with the introduction of Euflex (Euflexxa) at intervals of 1 week. In most cases, the effect lasts for about 6 months.

Euflexxa reduces knee pain associated with osteoarthritis and may be used when standard therapies (eg, physical therapy and pain medication) do not relieve pain enough. Euflexxa is contraindicated in patients suffering from hypersensitivity to hyaluronate-based products, knee infections, site infections, or skin conditions.

Many injectables for osteoarthritis are made from hyaluronic acid, which comes from rooster combs. Such preparations should not be used by patients suffering from allergies to birds, feathers or eggs. Euflexxa is not made from birds and is therefore safe for these patients. In addition, some of the other drugs require up to 5 injections to work, while Euflexxa requires only 3. This saves the patient time and reduces the number of visits to the doctor. Licensed medical professionals, such as orthopedic surgeons and other doctors, as well as various organizations (clinics, hospitals), can purchase Euflexxa from Medica Depot at a beneficial low wholesale price. Order Euflexxa for your clinic and you can help patients suffering from osteoarthritis feel better by relieving them of pain and discomfort, improving their mobility and making them more independent.