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Hematocrit chart. Hematocrit Levels: Understanding Normal Ranges, High and Low Values, and Their Impact on Health

What are normal hematocrit levels for men, women, and children. How do high and low hematocrit levels affect health. What causes abnormal hematocrit levels. How are hematocrit levels measured and interpreted.

What is Hematocrit and Why is it Important?

Hematocrit is a crucial measure of blood composition, representing the percentage of red blood cells in a person’s total blood volume. This vital indicator plays a significant role in assessing overall health and diagnosing various conditions. Red blood cells, also known as erythrocytes, are responsible for transporting oxygen throughout the body, making them essential for proper cellular function and energy production.

The importance of hematocrit lies in its ability to provide insights into several aspects of health:

  • Oxygen-carrying capacity of the blood
  • Potential presence of anemia or polycythemia
  • Hydration status
  • Overall blood health

Understanding hematocrit levels can help healthcare providers identify underlying health issues and guide treatment decisions. By measuring the proportion of red blood cells in the blood, doctors can assess a patient’s ability to deliver oxygen to tissues and organs, which is crucial for maintaining optimal health.

Normal Hematocrit Ranges: What’s Considered Healthy?

Normal hematocrit levels vary depending on several factors, including age, sex, and overall health status. While different institutions may define normal ranges slightly differently, a comprehensive 2017 cross-population study established the following typical ranges:

  • Adult males: 42-52%
  • Adult females: 37-47%
  • Children: 30-44% (varies with age and sex)
  • Newborns: Higher levels that gradually decrease with age

Is there a single universal hematocrit range for all individuals? No, hematocrit levels are influenced by various factors, making it essential to consider individual circumstances when interpreting results. Factors that can affect hematocrit levels include:

  • Pregnancy: Pregnant individuals may have lower levels due to increased blood volume
  • Altitude: Higher altitudes can lead to increased red blood cell production
  • Smoking: Chronic smokers may have elevated hematocrit levels
  • Chronic obstructive pulmonary disease (COPD): This condition can result in higher hematocrit levels
  • Recent blood transfusions: These can temporarily affect hematocrit readings

High Hematocrit Levels: Causes and Implications

Elevated hematocrit levels, also known as polycythemia, occur when the percentage of red blood cells in the blood exceeds the normal range. This condition can have significant health implications and may indicate underlying medical issues.

Potential Causes of High Hematocrit

  • Dehydration: Reduced blood plasma volume can concentrate red blood cells
  • Polycythemia vera: A rare blood disorder causing overproduction of red blood cells
  • Chronic lung diseases: Conditions like COPD can lead to increased red blood cell production
  • Heart disorders: Certain heart conditions may result in elevated hematocrit levels
  • Living at high altitudes: The body produces more red blood cells to compensate for lower oxygen levels
  • Smoking: Chronic smoking can stimulate red blood cell production

What are the risks associated with high hematocrit levels? Elevated hematocrit can lead to several health complications:

  • Increased blood viscosity, making circulation more difficult
  • Higher risk of blood clots, potentially leading to stroke or heart attack
  • Reduced oxygen delivery to tissues due to impaired blood flow
  • Increased workload on the heart

Healthcare providers may recommend lifestyle changes, medication, or other treatments to address high hematocrit levels and their underlying causes. Regular monitoring and appropriate interventions can help mitigate the risks associated with elevated hematocrit.

Low Hematocrit Levels: Understanding Anemia and Its Effects

Low hematocrit levels, typically below 35% in women and 41% in men, often indicate anemia. Anemia is a condition characterized by a reduced number of red blood cells or insufficient hemoglobin, the protein responsible for carrying oxygen in the blood.

Common Causes of Low Hematocrit

  • Iron deficiency: The most common cause of anemia worldwide
  • Vitamin B12 or folate deficiency: Essential for red blood cell production
  • Chronic diseases: Conditions like kidney disease or cancer can affect red blood cell production
  • Blood loss: Due to injury, surgery, or chronic conditions like heavy menstrual bleeding
  • Hemolytic anemia: Premature destruction of red blood cells
  • Bone marrow disorders: Conditions affecting the production of blood cells

How does anemia affect daily life? The symptoms of low hematocrit and anemia can significantly impact a person’s quality of life:

  • Fatigue and weakness
  • Shortness of breath, especially during physical activity
  • Pale skin and mucous membranes
  • Dizziness or lightheadedness
  • Cold hands and feet
  • Chest pain or irregular heartbeat
  • Cognitive difficulties, such as trouble concentrating

Treating low hematocrit levels typically involves addressing the underlying cause. This may include dietary changes, iron or vitamin supplements, medication, or in severe cases, blood transfusions. Regular monitoring and follow-up care are essential for managing anemia and preventing complications.

Hematocrit Testing: Methods and Interpretation

Hematocrit testing is typically performed as part of a complete blood count (CBC), a comprehensive panel of tests that evaluate various components of blood. Understanding the testing process and result interpretation is crucial for both healthcare providers and patients.

Methods of Hematocrit Measurement

  1. Microhematocrit method: A small blood sample is centrifuged to separate red blood cells from plasma, allowing for direct measurement of the red blood cell volume.
  2. Automated analyzers: Modern laboratories often use sophisticated machines that calculate hematocrit based on red blood cell count and mean cell volume.
  3. Estimated hematocrit: Sometimes calculated from hemoglobin levels, though this method is less precise.

What other tests are typically included in a CBC? A complete blood count often includes:

  • Red blood cell count
  • White blood cell count and differential
  • Platelet count
  • Hemoglobin level
  • Mean corpuscular volume (MCV)
  • Mean corpuscular hemoglobin (MCH)
  • Mean corpuscular hemoglobin concentration (MCHC)

Interpreting hematocrit results requires considering various factors, including the patient’s age, sex, medical history, and current health status. Healthcare providers use these results in conjunction with other tests and clinical findings to make accurate diagnoses and develop appropriate treatment plans.

Factors Influencing Hematocrit Levels: Beyond Health Conditions

While various health conditions can significantly affect hematocrit levels, several other factors can influence these measurements. Understanding these influences is crucial for accurate interpretation of test results and appropriate medical decision-making.

Environmental and Lifestyle Factors

  • Altitude: Living at high altitudes can increase hematocrit levels as the body produces more red blood cells to compensate for lower oxygen levels.
  • Hydration status: Dehydration can temporarily elevate hematocrit levels by concentrating blood components.
  • Exercise: Regular physical activity, particularly strength training, may affect hematocrit levels. A 2018 study found that middle-aged women who participated in a 16-week strength training program showed lower hematocrit levels at the end of the study.
  • Smoking: Chronic smoking can lead to increased red blood cell production and elevated hematocrit levels.
  • Alcohol consumption: Excessive alcohol intake can affect red blood cell production and lifespan.

How do seasonal changes impact hematocrit levels? Some studies suggest that hematocrit levels may vary slightly with seasons, potentially due to changes in temperature, humidity, and daylight hours. However, these variations are generally minor and within normal ranges for most individuals.

Demographic and Physiological Factors

  • Age: Hematocrit levels naturally change throughout life, with newborns having higher levels that gradually decrease as they age.
  • Sex: Adult males typically have higher hematocrit levels than adult females due to the influence of hormones and menstrual blood loss in women.
  • Pregnancy: Expectant mothers often experience a decrease in hematocrit levels due to the body’s increased blood volume during pregnancy.
  • Ethnicity: Some blood disorders, such as sickle cell anemia, are more prevalent in certain ethnic groups, potentially affecting hematocrit levels.

Understanding these influencing factors helps healthcare providers contextualize hematocrit test results and make more informed decisions about patient care and potential interventions.

Hematocrit and Disease Management: Beyond Diagnosis

Hematocrit testing plays a crucial role not only in diagnosing conditions but also in monitoring disease progression and treatment efficacy. This versatile blood parameter provides valuable insights for healthcare providers managing various medical conditions.

Hematocrit in Chronic Disease Management

  • Cancer treatment: Regular hematocrit tests help monitor the effects of chemotherapy on bone marrow function and guide supportive care decisions.
  • Kidney disease: Hematocrit levels are essential for assessing anemia in chronic kidney disease patients and managing erythropoietin therapy.
  • Heart failure: Monitoring hematocrit can help evaluate fluid status and guide diuretic therapy in heart failure patients.
  • Polycythemia vera: Regular testing is crucial for monitoring disease progression and treatment response in this blood disorder characterized by excessive red blood cell production.

How often should hematocrit levels be checked in chronic disease management? The frequency of hematocrit testing varies depending on the specific condition, treatment regimen, and individual patient factors. Healthcare providers typically establish personalized monitoring schedules based on clinical guidelines and patient needs.

Hematocrit in Acute Care Settings

  • Trauma and surgery: Rapid hematocrit testing helps assess blood loss and guide transfusion decisions in emergency situations.
  • Sepsis: Monitoring hematocrit levels can provide insights into fluid status and help guide resuscitation efforts in septic patients.
  • Acute anemia: Serial hematocrit measurements help evaluate the severity and progression of acute anemia, guiding treatment decisions.

By incorporating hematocrit testing into comprehensive disease management strategies, healthcare providers can optimize patient care, adjust treatments as needed, and improve overall outcomes across a wide range of medical conditions.

Optimizing Hematocrit Levels: Strategies for Maintaining Healthy Blood Composition

Maintaining optimal hematocrit levels is crucial for overall health and well-being. While some factors affecting hematocrit are beyond an individual’s control, there are several strategies that can help promote healthy blood composition.

Dietary Approaches

  • Iron-rich foods: Consuming lean meats, fish, beans, and leafy green vegetables can help prevent iron-deficiency anemia.
  • Vitamin B12 and folate: Including foods like eggs, dairy products, and fortified cereals in the diet supports red blood cell production.
  • Vitamin C: This nutrient enhances iron absorption when consumed alongside iron-rich foods.
  • Hydration: Maintaining proper fluid intake helps prevent dehydration-induced hematocrit elevation.

Can dietary supplements help optimize hematocrit levels? While supplements can be beneficial for individuals with diagnosed deficiencies, it’s essential to consult a healthcare provider before starting any supplementation regimen, as excessive intake of certain nutrients can be harmful.

Lifestyle Modifications

  • Regular exercise: Engaging in moderate physical activity can help maintain healthy blood composition.
  • Smoking cessation: Quitting smoking can help normalize hematocrit levels and improve overall health.
  • Stress management: Chronic stress can affect blood cell production, so practicing stress-reduction techniques may be beneficial.
  • Altitude considerations: Individuals living at high altitudes may need to take extra precautions to maintain optimal hematocrit levels.

By adopting these dietary and lifestyle strategies, individuals can support healthy hematocrit levels and contribute to their overall well-being. However, it’s important to remember that significant changes in hematocrit levels should always be evaluated by a healthcare professional to rule out underlying medical conditions.

Understanding hematocrit levels and their implications is crucial for maintaining optimal health and identifying potential health issues early. By recognizing the factors that influence hematocrit and working closely with healthcare providers, individuals can take proactive steps to support healthy blood composition and overall well-being. Regular health check-ups, including complete blood count tests, remain an essential tool in monitoring hematocrit levels and ensuring timely intervention when necessary.

What it is, levels, high and low range

Hematocrit is the percentage of red blood cells in a person’s blood. A typical hematocrit range in healthy adults is 37–52%. This varies depending on a person’s sex and age.

Authors of a 2017 study identified the above typical range.

Low red blood cell levels indicate conditions such as anemia. High red blood cell levels could signal polycythemia, increasing a person’s chance of developing a blood clot.

If a person feels tired, dizzy, or short of breath, a doctor may want to test their hematocrit levels to see if those levels fall into a normal range or not.

Read on to learn more about what this measure of red blood cell volume means, symptoms of abnormal levels, and what low and high levels might indicate.

Hematocrit measures the percentage of red blood cells in the body. For example: if a person has 50 milliliters (ml) of red blood cells in 100 ml of blood, their hematocrit level is 50%.

Red blood cells transport oxygen around the body and give blood its characteristic red color. In addition to oxygen, they also contain hemoglobin, a protein that binds to oxygen molecules. This allows red blood cells to pick up oxygen from the lungs and deliver it throughout the body.

An adequate amount of red blood cells is essential to keep the body’s processes running smoothly.

Many conditions can affect red blood cell production or its life cycle. This can make it difficult for a medical professional to diagnose these conditions. A doctor will use a hematocrit test to confirm whether a person’s red blood cell count is affecting a health condition.

Doctors usually test hematocrit levels as part of a complete blood count (CBC).

A CBC is composed of a range of tests and may include:

  • red blood cell count
  • reticulocyte count (young red blood cells)
  • an analysis of hemoglobin levels
  • an analysis of red blood cells, including size and shape
  • white blood cell tests
  • platelet tests

A doctor will also consider a person’s sex, race, and age. It is important to note that certain blood-related conditions, such as sickle-cell anemia, affect particular demographic groups at higher rates.

Learn more about sickle cell anemia in African Americans here.

A doctor may request frequent hematocrit tests to monitor the effect of chemotherapy on a person’s bone marrow.

Both high and low hematocrit levels can be detrimental to a person’s health and result from various conditions and lifestyle factors.

What are normal hematocrit levels?

Different institutions will define normal hematocrit levels differently. However, a 2017 cross-population study found the following ranges to be typical.

  • Male: 42-52%
  • Female: 37-47%
  • Children: 30–44%, depending on their age and sex

Newborn babies have high hematocrit levels that gradually decrease as they get older.

If a person has recently received a blood transfusion, it may affect their results. Additionally, pregnant individuals may have lower levels than usual because the body increases its blood volume during pregnancy.

Other factors, such as smoking and chronic obstructive pulmonary disease (COPD), may push levels into a higher range.

Low levels

A hematocrit level below 35% in women and 41% in men is low. A level under this value can signify chronic anemia.

High levels

Hematocrit levels above the typical ranges can have adverse effects. It may indicate serious underlying health conditions.

Accuracy of results

Results from hematocrit tests are typically accurate and provide a clear reading of a person’s red blood cell levels.

However, the percentage of red blood cells in someone’s blood can change depending on various lifestyle factors and even environmental changes. According to research, red blood cell counts tend to increase at high altitudes.

Exercise, particularly strength training, may also affect hematocrit levels. A 2018 study found that females who participated in 16 weeks of strength exercise had lower levels at the end than when they started. However, the study had a small sample size of 26 middle-aged, sedentary Turkish women. This means that these findings aren’t necessarily representative of a wider population.

Dehydration can also raise hematocrit levels, so this test is useful if a doctor suspects severe dehydration is the cause of a person’s symptoms.

When a person has low hematocrit levels, they tend to present with the following symptoms:

  • pale complexion
  • weakness
  • fatigue
  • low energy
  • trouble breathing
  • irregular heartbeat
  • cold hands or feet

These symptoms also indicate anemia, a condition where hemoglobin levels are lower than normal. Hemoglobin is a protein found in red blood cells that carries oxygen around the body.

Mild anemia is treatable, and it is particularly common in women. Severe anemia could signal a more serious underlying health condition that requires more extensive treatment.

Doctors associate anemia with several health conditions, including:

Nutrient deficiency

A person may lack B12, folate, or iron in their diet.

Learn more about how nutrient deficiency anemia is diagnosed and treated.

Chronic bleeding

This commonly occurs due to digestive tract ulcers, which are sores caused by the bacteria H.pylori or chronic use of anti-inflammatory medications such as ibuprofen, other nonsteroidal anti-inflammatory drugs (NSAIDs), and aspirin. Many women also experience excessive blood loss from heavy menstrual bleeding.

Bone marrow disorder

This includes aplastic anemia, which damages stem cells in bone marrow.

Cancer

These cancers spread to bone marrow, such as leukemia and lymphoma.

Learn more about bone marrow cancers here.

Kidney failure

Kidney disease can lower the production of red blood cells, reducing hematocrit levels.

Thalassemia

When a person has this condition, their body does not produce enough hemoglobin.

Learn more about thalassemia here.

Sickle cell anemia

This condition changes the shape of red blood cells. These cells die earlier than normal, and they also clump together, which impairs blood flow.

Learn more about sickle cell anemia here.

Autoimmune disease

Conditions like rheumatoid arthritis and lupus may reduce red blood cell count.

Learn more about autoimmune diseases here.

When a person has high hematocrit levels, they tend to present with these symptoms:

  • flushed skin
  • dizziness
  • vision problems
  • headaches
  • enlarged spleen

These symptoms signal polycythemia, a condition where the body produces too many red blood cells. This means blood is thicker and clots more easily.

Doctors cannot cure polycythemia, so treatment focuses on symptom management. The main goal is to avoid stroke and deep vein thrombosis (DVT), which is a blood clot usually occurring in a deep vein in the leg.

In some cases, dehydration causes polycythemia. When a person does not drink enough, their plasma levels drop, increasing the proportion of red blood cells in their blood volume. A person can lower their red blood cell count by rehydrating.

Some conditions that can cause high hematocrit levels include:

Lung or pulmonary disease

When the lungs cannot absorb oxygen effectively, and oxygen levels drop, the body compensates by making more red blood cells. One common pulmonary disease causing this is COPD.

Learn more about COPD here.

Heart disease

If the structure of a person’s heart reduces its ability to pump blood around the body, it can no longer sustain vital organs with oxygen. To try and overcome the oxygen deficit, the body produces more red blood cells.

Learn more about heart disease here.

Kidney cancer

Sometimes kidney cancer cells create more erythropoietin. Erythropoietin is a hormone that tells the bone marrow to create more red blood cells.

Learn more about kidney cancer here.

Genetic disease

The JAK2 gene, which controls the number of blood cells made in the bone marrow, can affect certain conditions. When someone has a mutated JAK2 gene, the body could make a protein that signals the bone marrow to create more red blood cells than it needs.

Learn more about genetic disorders here.

A person should speak with a doctor if they are experiencing any of the symptoms listed above that could be a sign of high or low hematocrit levels, including fatigue, weakness, vision problems, and dizziness.

These symptoms can also indicate an underlying condition, so a person must contact a doctor promptly to prevent future complications.

If a person is receiving chemotherapy treatment, a doctor should perform regular hematocrit tests to monitor bone marrow health.

Hematocrit is the percentage of blood cells in a person’s blood volume. A doctor may test an individual’s hematocrit level due to certain symptoms.

A low hematocrit level means there are too few red blood cells in the body. In these cases, a person may experience symptoms that signal anemia. Common symptoms include fatigue, weakness, and low energy.

If a person has too many red blood cells, they have a high hematocrit level. A person may experience dizziness and headaches, which can be a sign of the condition polycythemia.

Demographic and lifestyle factors can influence a person’s hematocrit levels. For example, males tend to have higher levels than females. Pregnant individuals can experience a decrease in hematocrit levels, and strength training may also reduce levels.

There are also several health conditions that can cause hematocrit levels outside the normal range. Excessive bleeding, thalassemia, and kidney disease are causes of low levels. COPD and sickle cell anemia can cause high levels.

Read this article in Spanish.

What it is, levels, high and low range

Hematocrit is the percentage of red blood cells in a person’s blood. A typical hematocrit range in healthy adults is 37–52%. This varies depending on a person’s sex and age.

Authors of a 2017 study identified the above typical range.

Low red blood cell levels indicate conditions such as anemia. High red blood cell levels could signal polycythemia, increasing a person’s chance of developing a blood clot.

If a person feels tired, dizzy, or short of breath, a doctor may want to test their hematocrit levels to see if those levels fall into a normal range or not.

Read on to learn more about what this measure of red blood cell volume means, symptoms of abnormal levels, and what low and high levels might indicate.

Hematocrit measures the percentage of red blood cells in the body. For example: if a person has 50 milliliters (ml) of red blood cells in 100 ml of blood, their hematocrit level is 50%.

Red blood cells transport oxygen around the body and give blood its characteristic red color. In addition to oxygen, they also contain hemoglobin, a protein that binds to oxygen molecules. This allows red blood cells to pick up oxygen from the lungs and deliver it throughout the body.

An adequate amount of red blood cells is essential to keep the body’s processes running smoothly.

Many conditions can affect red blood cell production or its life cycle. This can make it difficult for a medical professional to diagnose these conditions. A doctor will use a hematocrit test to confirm whether a person’s red blood cell count is affecting a health condition.

Doctors usually test hematocrit levels as part of a complete blood count (CBC).

A CBC is composed of a range of tests and may include:

  • red blood cell count
  • reticulocyte count (young red blood cells)
  • an analysis of hemoglobin levels
  • an analysis of red blood cells, including size and shape
  • white blood cell tests
  • platelet tests

A doctor will also consider a person’s sex, race, and age. It is important to note that certain blood-related conditions, such as sickle-cell anemia, affect particular demographic groups at higher rates.

Learn more about sickle cell anemia in African Americans here.

A doctor may request frequent hematocrit tests to monitor the effect of chemotherapy on a person’s bone marrow.

Both high and low hematocrit levels can be detrimental to a person’s health and result from various conditions and lifestyle factors.

What are normal hematocrit levels?

Different institutions will define normal hematocrit levels differently. However, a 2017 cross-population study found the following ranges to be typical.

  • Male: 42-52%
  • Female: 37-47%
  • Children: 30–44%, depending on their age and sex

Newborn babies have high hematocrit levels that gradually decrease as they get older.

If a person has recently received a blood transfusion, it may affect their results. Additionally, pregnant individuals may have lower levels than usual because the body increases its blood volume during pregnancy.

Other factors, such as smoking and chronic obstructive pulmonary disease (COPD), may push levels into a higher range.

Low levels

A hematocrit level below 35% in women and 41% in men is low. A level under this value can signify chronic anemia.

High levels

Hematocrit levels above the typical ranges can have adverse effects. It may indicate serious underlying health conditions.

Accuracy of results

Results from hematocrit tests are typically accurate and provide a clear reading of a person’s red blood cell levels.

However, the percentage of red blood cells in someone’s blood can change depending on various lifestyle factors and even environmental changes. According to research, red blood cell counts tend to increase at high altitudes.

Exercise, particularly strength training, may also affect hematocrit levels. A 2018 study found that females who participated in 16 weeks of strength exercise had lower levels at the end than when they started. However, the study had a small sample size of 26 middle-aged, sedentary Turkish women. This means that these findings aren’t necessarily representative of a wider population.

Dehydration can also raise hematocrit levels, so this test is useful if a doctor suspects severe dehydration is the cause of a person’s symptoms.

When a person has low hematocrit levels, they tend to present with the following symptoms:

  • pale complexion
  • weakness
  • fatigue
  • low energy
  • trouble breathing
  • irregular heartbeat
  • cold hands or feet

These symptoms also indicate anemia, a condition where hemoglobin levels are lower than normal. Hemoglobin is a protein found in red blood cells that carries oxygen around the body.

Mild anemia is treatable, and it is particularly common in women. Severe anemia could signal a more serious underlying health condition that requires more extensive treatment.

Doctors associate anemia with several health conditions, including:

Nutrient deficiency

A person may lack B12, folate, or iron in their diet.

Learn more about how nutrient deficiency anemia is diagnosed and treated.

Chronic bleeding

This commonly occurs due to digestive tract ulcers, which are sores caused by the bacteria H. pylori or chronic use of anti-inflammatory medications such as ibuprofen, other nonsteroidal anti-inflammatory drugs (NSAIDs), and aspirin. Many women also experience excessive blood loss from heavy menstrual bleeding.

Bone marrow disorder

This includes aplastic anemia, which damages stem cells in bone marrow.

Cancer

These cancers spread to bone marrow, such as leukemia and lymphoma.

Learn more about bone marrow cancers here.

Kidney failure

Kidney disease can lower the production of red blood cells, reducing hematocrit levels.

Thalassemia

When a person has this condition, their body does not produce enough hemoglobin.

Learn more about thalassemia here.

Sickle cell anemia

This condition changes the shape of red blood cells. These cells die earlier than normal, and they also clump together, which impairs blood flow.

Learn more about sickle cell anemia here.

Autoimmune disease

Conditions like rheumatoid arthritis and lupus may reduce red blood cell count.

Learn more about autoimmune diseases here.

When a person has high hematocrit levels, they tend to present with these symptoms:

  • flushed skin
  • dizziness
  • vision problems
  • headaches
  • enlarged spleen

These symptoms signal polycythemia, a condition where the body produces too many red blood cells. This means blood is thicker and clots more easily.

Doctors cannot cure polycythemia, so treatment focuses on symptom management. The main goal is to avoid stroke and deep vein thrombosis (DVT), which is a blood clot usually occurring in a deep vein in the leg.

In some cases, dehydration causes polycythemia. When a person does not drink enough, their plasma levels drop, increasing the proportion of red blood cells in their blood volume. A person can lower their red blood cell count by rehydrating.

Some conditions that can cause high hematocrit levels include:

Lung or pulmonary disease

When the lungs cannot absorb oxygen effectively, and oxygen levels drop, the body compensates by making more red blood cells. One common pulmonary disease causing this is COPD.

Learn more about COPD here.

Heart disease

If the structure of a person’s heart reduces its ability to pump blood around the body, it can no longer sustain vital organs with oxygen. To try and overcome the oxygen deficit, the body produces more red blood cells.

Learn more about heart disease here.

Kidney cancer

Sometimes kidney cancer cells create more erythropoietin. Erythropoietin is a hormone that tells the bone marrow to create more red blood cells.

Learn more about kidney cancer here.

Genetic disease

The JAK2 gene, which controls the number of blood cells made in the bone marrow, can affect certain conditions. When someone has a mutated JAK2 gene, the body could make a protein that signals the bone marrow to create more red blood cells than it needs.

Learn more about genetic disorders here.

A person should speak with a doctor if they are experiencing any of the symptoms listed above that could be a sign of high or low hematocrit levels, including fatigue, weakness, vision problems, and dizziness.

These symptoms can also indicate an underlying condition, so a person must contact a doctor promptly to prevent future complications.

If a person is receiving chemotherapy treatment, a doctor should perform regular hematocrit tests to monitor bone marrow health.

Hematocrit is the percentage of blood cells in a person’s blood volume. A doctor may test an individual’s hematocrit level due to certain symptoms.

A low hematocrit level means there are too few red blood cells in the body. In these cases, a person may experience symptoms that signal anemia. Common symptoms include fatigue, weakness, and low energy.

If a person has too many red blood cells, they have a high hematocrit level. A person may experience dizziness and headaches, which can be a sign of the condition polycythemia.

Demographic and lifestyle factors can influence a person’s hematocrit levels. For example, males tend to have higher levels than females. Pregnant individuals can experience a decrease in hematocrit levels, and strength training may also reduce levels.

There are also several health conditions that can cause hematocrit levels outside the normal range. Excessive bleeding, thalassemia, and kidney disease are causes of low levels. COPD and sickle cell anemia can cause high levels.

Read this article in Spanish.

Hemogram with leukogram (B-CBC 5-diff, B-CBC 3-diff )

Hemogram with leukogram (B-CBC 5-diff, B-CBC 3-diff ) – SYNLAB Eesti

A hemogram is a comprehensive study in which the content of hemoglobin in the blood is measured, blood cells are counted: leukocytes, erythrocytes, platelets, and erythrocyte and platelet indices are calculated.

Leukogram with 5-component leukogram presented in absolute values:

  • neutrophils
  • eosinophils
  • basophils
  • lymphocytes
  • monocytes

Leukogram with 3-component leukogram presented in absolute values:

  • neutrophils
  • lymphocytes
  • MXD cells (monocytes, eosinophils, basophils)

Readings:

  • Diagnosis of anemia. In addition to measuring hemoglobin and RBC levels, red blood evaluation also considers mean red cell volume (MCV), mean hemoglobin per erythrocyte (MCH), and mean hemoglobin concentration in erythrocyte (MCHC), as well as the red blood cell distribution index by volume (anisocytosis index RDW).
  • Determination of the presence of a pathological process based on changes in the number of leukocytes and in the leukogram, for example, infection, inflammation, allergy, malignancy, immunosuppression,.
  • Determination of the platelet count is an important test in the presence of signs of bleeding. A change in the number of platelets, together with the indices characterizing them (MPV – mean platelet volume, PDW – platelet distribution width by volume) indicates a possible disturbance in platelet production or their accelerated destruction.

Analysis method: Flow cytometry

See table for reference values ​​

See table for critical values ​​

Interpretation of the result:

HEMOGLOBIN, HEMATOCRITE, RED CYTES

Normally, the values ​​of hemoglobin, hematocrit and erythrocytes are interconnected and change in the same direction.

  • Low values: anemia
  • High values: hypovolemia, polycythemia, chronic oxygen deficiency, smoking.

RBC INDICES: MCV, MCH, MCHC, RDW-CV

RBC indices characterize the morphological type of anemia.

Normocytic normochromic (MCV normal, MSI normal):

  • Early stage iron deficiency
  • Chronic disease (e.g. cancer)
  • Acute blood loss
  • Aplastic anemia
  • Acquired hemolytic anemia (e.g. prosthetic heart valves)

Microcytic hypochromic (MCV ↓, MCH ↓):

  • Advanced iron deficiency
  • Thalassemia
  • Lead poisoning

Microcytic normochromic (MCV ↓, MCH normal):

  • Kidney disease (erythropoietin deficiency)

Macrocytic normochromic (MCV ↑, MCH normal):

  • Folic acid or vitamin B12 deficiency
  • Chemotherapy

Other possible causes of MCV ↑: pregnancy, certain drugs, alcohol.

With significant changes in MCV, it is necessary to evaluate the morphology of erythrocytes in the blood smear preparation.

RDW

Indicates Indicates the variability in the amount of erythrocytes (anisocytosis).

L LEUKOCYTES, LEUKOGRAM

  • There are many possible causes of leukocytosis. More accurate information is given by an automatic 5-component leukogram of 5 types of leukocytes.
  • A total white blood cell count that falls within the reference interval does not rule out abnormalities in different white blood cell populations.
  • Neutrophilia – acute inflammation, toxic injury, immune disease, myeloproliferative disease.
  • Eosinophilia – allergies, parasites, immune syndromes, malignant diseases (lymphoma, carcinoma).
  • Basophilia – allergy, myeloproliferative diseases.
  • Monocytosis – chronic inflammation, diseases occurring with tissue damage, chronic myeloproliferative diseases.
  • Lymphocytosis – viral infections, reactive conditions, malignant lymphoproliferative diseases.
  • Leukopenia – usually occurs from neutropenia. Occurs with viral infections, toxic (for example, drugs) or immune damage to the hematopoietic function, and with acute leukemia.

PLATELETS

  • Thrombocytopenia most often occurs in connection with viral infections, the use of drugs, some autoimmune diseases, liver diseases, megaloblastic anemia, alcoholism, diseases of the hematopoietic system, hypersplenism.
  • So-called pseudothrombocytopenia occurs when several aggregated platelets are counted by the analyzer as one large platelet.
    • This may be due to insufficient mixing of blood with anticoagulant after sample collection or platelet sensitivity to EDEDTA. In this case, to count the platelets, the test should be repeated by taking the blood into the citrate tube used for coagulation tests (with a blue stopper). Platelet aggregates are clearly visible by microscopic examination of a blood smear.
    • Thrombocytosis usually occurs in association with myeloproliferative disorders such as polycythemia and essential thrombocythemia and after splenectomy.
  • Elevated platelet values ​​often occur together with reactive changes in leukocytes in bacterial infections.

PLATELET INDICES: MPV, PDW

MPV and PDW are important in clarifying the essence of the nature of thrombocytopenia and thrombocytosis.

  • Elevated MRV and thrombocytopenia – indicates a normal regenerative ability of thrombocytopenia.
  • Artifact MPV increase:
    • Long time between sample collection and analysis itself – platelets swell in blood sample cells EDTA
    • Platelet aggregates
  • High PDW and MPV values ​​are a common finding in chronic myeloproliferative diseases.
  • Increased PDW and decreased platelet count are common findings in megaloblastic anemias.
  • Normal PDW and platelet count >500 × 109/L – often associated with reactive changes

Indications for blood smear microscopy

If the result of the absolute blood count is one If any of the following indicators are present in the hemogram, and if the analyzer reports atypical morphology, then blood smear microscopy is performed as a clarifying study.

Parameter Hemogram with
3-component leukogram
Hemogram with
5-component leukogram
Erythrocytes < 2.0 x 10 12 /L
> 6.5 x 10 12 /L
< 2.0 x 1012/L
> 6.5 x 1012/L
Hemoglobin < 80 g/L
> 200 g/L
< 80 g/L
> 200 g/L
Leukocytes < 1. 5 x 109/L
> 15 x 109/L (> 2 l)
> 20 x 109/L (< 2 l)
≤ 2 x 10 9 /L
< 1.5 x 109/L
> 15 x 109/L (> 2 l)
> 20 x 109/L (< 2 l)
≤ 2 x 10 9 /L
Neutrophils < 1.0 x 109/L
> 20 x 109/L
< 1.0 x 109/L
> 20 x 109/L
Lymphocytes < 0.8 x 109/L
> 5.0 x 109/L (> 12 l)
> 7.0 x 109/L (< 12 l)
< 0.8 x 109/L
> 5.0 x 109/L (> 12 l)
> 7.0 x 109/L (< 12 l)
Monocytes > 1.5 x 109/L (> 12 l)
> 3.0 x 109/L (< 12 l)
MXD cells
(monocytes, eosinophils, basophils)
> 2 x 109/L (> 12 l)
> 3.5 x 109/L (< 12 l)
Platelets < 100 x 109/L
> 1000 x 109/L
< 100 x 109/L
> 1000 x 109/L

Veterinary Glucose and Ketone Analyzer

    • Portable Veterinary Glucose and Ketone Analyzer
    • No calibration codes
    • Measurement of the level of beta-hydroxybutyrate in the blood of animals
    • The “gold standard” for detecting subclinical ketosis
    • Minimum blood sample – 0. 4 µl for glucose and 0.8 µl for ketones
    • Fast Results – 4 seconds for Glucose, 10 seconds for Ketones
    • Accuracy equivalent to
    • laboratory analyzer

    Glucose and Ketone Analyzer Applications NovaVet Glu/Ket
    NovaVet Veterinary Glucose and Ketone Analyzer measures beta-hydroxybutyrate (BHB) levels in animal blood and is the gold standard for subclinical detection. ketosis using a tiny drop of blood. The NovaVet Glucose and Ketone Analyzer provides an accuracy comparable to reference laboratory tests at the subclinical BHB threshold for predicting health risk in early lactating cows. Quantitative BHB results rule out subjective interpretation of the semi-quantitative color charts used when testing milk or urine ketones.

    Glucose and Ketone Analyzer NovaVet detects clinical ketosis in early lactation in a dairy farm.
    The transition of dairy cows to breastfeeding is a critical moment and a decisive factor in the health and performance of the cow throughout the entire period of feeding. All transitional cows are at risk of clinical ketosis characterized by anorexia, anorexia, signs of nervous dysfunction, etc. Clinical ketosis causes economic damage to the dairy farm due to:

    • Reduced milk production;
    • Poor quality milk;
    • Mastitis;
    • Treatment costs.

    NovaVet corrects the results of the analysis for ketones and glucose according to the hematocrit level.
    Cow hematocrit levels differ significantly from human blood hematocrit levels and may vary during lactation depending on sampling site, season and breed. Devices designed to measure blood ketones for humans may give erroneous results in cow blood due to lower hematocrit levels. NovaVet measures the hematocrit level in each blood sample and corrects the results for ketones or glucose to ensure the results are accurate.

    Measuring glucose and ketones on one veterinary analyzer.
    Glucose testing can be used to make important clinical decisions regarding intravenous glucose administration. Both glucose and ketone tests use the same device, you just need to insert the appropriate test strip.

    Accurate quantitative results of beta-hydroxybutyrate ( BHB ).
    NovaVet provides an accuracy comparable to reference laboratory tests at the subclinical BHB threshold for predicting health risk in early lactating cows. Quantitative BHB results rule out subjective interpretation of the semi-quantitative color charts used when testing milk or urine ketones.

    Specifications:

    • B/W LCD with large digits (30 mm)
    • Traditional Liquid Quality Controls
    • Data storage: 400 tests of analysis results and quality controls
    • Communication: data transfer via USB port
    • Replacement battery type: 3V Li battery
    • Battery life: Minimum for 1000 tests
    • Dimensions: 91.4 x 58.4 x 22.9 mm
    • Weight: 75 g.

    NovaVet® Glucose Test Strips

    Tests:
    Measurement tests: hematocrit corrected glucose
    Output test: glucose
    Analysis time: 4 seconds
    Sample volume: 0.