Holistic treatment for pancreatitis. Holistic Treatments for Pancreatitis: Natural Remedies to Relieve Symptoms

09.07.202312.06.2023 by alexxlab

What are effective natural remedies for pancreatitis. How can diet and lifestyle changes help manage pancreatitis symptoms. Which foods and supplements can reduce pancreatic inflammation. What holistic approaches can complement medical treatment for pancreatitis.

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Understanding Pancreatitis: Causes, Symptoms, and Diagnosis

Pancreatitis is a condition characterized by inflammation of the pancreas, an organ located behind the stomach in the upper abdomen. This inflammation can be acute (sudden and severe) or chronic (long-lasting), and it can significantly impact a person’s quality of life.

The primary causes of pancreatitis include:

Gallstones
Excessive alcohol consumption
High triglyceride levels
Certain medications
Genetic factors
Autoimmune disorders

Common symptoms of pancreatitis include:

Upper abdominal pain that may radiate to the back
Nausea and vomiting
Fever
Rapid pulse
Tenderness when touching the abdomen
Unintended weight loss

Diagnosis typically involves blood tests, imaging studies such as CT scans or MRIs, and sometimes endoscopic procedures. Early diagnosis and proper management are crucial for preventing complications and improving outcomes.

The Power of Turmeric in Managing Pancreatitis Symptoms

Turmeric, a vibrant yellow spice commonly used in Indian cuisine, has gained significant attention for its potential therapeutic benefits in managing pancreatitis symptoms. The active compound in turmeric, curcumin, is known for its powerful anti-inflammatory and antioxidant properties.

How does turmeric help with pancreatitis?

Reduces inflammation: Curcumin inhibits inflammatory pathways in the body, potentially alleviating pancreatic inflammation.
Antioxidant effects: It helps neutralize free radicals that can contribute to tissue damage in the pancreas.
Pain relief: Some studies suggest that curcumin may help reduce abdominal pain associated with pancreatitis.

To incorporate turmeric into your diet, consider:

Adding it to rice or vegetable dishes
Mixing it with warm milk to create “golden milk”
Taking curcumin supplements under medical supervision

While turmeric shows promise, it’s essential to consult with a healthcare provider before using it as a complementary treatment for pancreatitis, especially if you’re taking other medications.

Ginger: A Natural Anti-Inflammatory for Pancreatic Health

Ginger, a root known for its distinctive flavor and aroma, has been used for centuries in traditional medicine. Recent research suggests that ginger may offer benefits for those suffering from pancreatitis due to its anti-inflammatory and antioxidant properties.

How can ginger help with pancreatitis symptoms?

Reduces inflammation: Gingerols and shogaols, active compounds in ginger, have been shown to inhibit inflammatory processes in the body.
Alleviates nausea: Ginger is well-known for its ability to reduce nausea and vomiting, common symptoms of pancreatitis.
Supports digestion: It may help stimulate the production of digestive enzymes, aiding in nutrient absorption.

To incorporate ginger into your diet:

Brew fresh ginger tea by steeping sliced ginger in hot water
Add grated ginger to soups, stir-fries, or smoothies
Consider ginger supplements, but consult your healthcare provider first

While ginger is generally safe, it’s important to use it in moderation and be aware of potential interactions with medications, particularly blood thinners.

Coconut Oil: A Gentle Fat Option for Pancreatic Support

Coconut oil has gained popularity in recent years for its potential health benefits, including its possible role in supporting pancreatic health. Unlike many other oils, coconut oil contains medium-chain triglycerides (MCTs), which are easier for the body to digest and may be less taxing on the pancreas.

Why might coconut oil be beneficial for those with pancreatitis?

Easy digestion: MCTs require less pancreatic enzymes for digestion compared to long-chain fatty acids.
Anti-inflammatory properties: Some studies suggest that coconut oil may have anti-inflammatory effects.
Nutrient absorption: It may enhance the absorption of fat-soluble vitamins and minerals.

How to use coconut oil in your diet:

Use it as a cooking oil for low to medium-heat cooking
Add a small amount to smoothies or hot beverages
Use it as a replacement for butter in baking recipes

It’s important to note that while coconut oil may offer benefits, it should be consumed in moderation as part of a balanced diet. Always consult with a healthcare provider before making significant changes to your diet, especially if you have pancreatitis.

The Role of Spinach and Other Leafy Greens in Pancreatic Health

Spinach and other leafy greens are nutrient powerhouses that may play a significant role in supporting pancreatic health and potentially alleviating symptoms of pancreatitis. These vegetables are packed with vitamins, minerals, and antioxidants that can contribute to overall digestive health.

How do leafy greens benefit those with pancreatitis?

Rich in antioxidants: They help combat oxidative stress and reduce inflammation in the body, including the pancreas.
Vitamin K: This nutrient found abundantly in leafy greens may help regulate insulin and glucose metabolism.
Fiber content: The high fiber in these vegetables supports digestive health and may help manage blood sugar levels.

Incorporating leafy greens into your diet:

Add spinach or kale to smoothies for a nutrient boost
Use mixed greens as a base for salads
Lightly sautÃ© leafy greens as a side dish
Include them in soups and stews for added nutrition

While leafy greens are generally safe and nutritious, it’s important to introduce them gradually if you’re not used to consuming them regularly. Some people with digestive issues may need to start with cooked greens rather than raw to aid digestion.

Mushrooms: Powerful Allies in Fighting Pancreatic Inflammation

Various types of mushrooms have been studied for their potential therapeutic effects on pancreatic health. Certain mushrooms, particularly medicinal varieties like Reishi, Shiitake, and Maitake, contain compounds that may help reduce inflammation and support overall pancreatic function.

What makes mushrooms beneficial for pancreatitis?

Anti-inflammatory compounds: Many mushrooms contain beta-glucans and other substances that can help reduce inflammation.
Immune system support: Certain mushrooms may help modulate the immune system, potentially beneficial in autoimmune-related pancreatitis.
Antioxidant properties: Mushrooms are rich in antioxidants that can help protect pancreatic cells from damage.

Incorporating mushrooms into your diet:

Add sliced mushrooms to stir-fries or omelets
Use mushroom powder in soups or broths
Consider mushroom supplements, but consult with a healthcare provider first
Try mushroom teas or extracts for a concentrated dose of beneficial compounds

While mushrooms offer potential benefits, it’s crucial to ensure they’re from a reputable source and to introduce them gradually into your diet. Some people may have allergies or sensitivities to certain types of mushrooms, so monitor your body’s response when trying new varieties.

Dietary and Lifestyle Changes to Support Pancreatic Health

Managing pancreatitis often requires a comprehensive approach that includes not only medical treatment but also dietary and lifestyle modifications. These changes can help reduce the burden on the pancreas, manage symptoms, and support overall digestive health.

Key Dietary Considerations:

Low-fat diet: Reducing fat intake can help ease the workload on the pancreas.
Small, frequent meals: This approach can help prevent overtaxing the digestive system.
Avoiding alcohol: Alcohol is a common trigger for pancreatitis and should be avoided.
Staying hydrated: Adequate fluid intake is crucial for overall health and can help prevent dehydration during bouts of pancreatitis.

Lifestyle Modifications:

Smoking cessation: Smoking can exacerbate pancreatitis and increase the risk of pancreatic cancer.
Stress management: Chronic stress can impact digestive health, so incorporating stress-reduction techniques is beneficial.
Regular exercise: Gentle physical activity can support overall health and may help with symptom management.
Adequate sleep: Proper rest is crucial for the body’s healing and repair processes.

Implementing these dietary and lifestyle changes can significantly impact the management of pancreatitis. However, it’s essential to work closely with a healthcare provider to develop a personalized plan that addresses your specific needs and medical history.

Complementary Therapies for Pancreatitis Management

While conventional medical treatments are the cornerstone of pancreatitis management, many patients find relief by incorporating complementary therapies into their care plan. These approaches can help manage symptoms, reduce stress, and improve overall quality of life.

Acupuncture:

This traditional Chinese medicine technique involves inserting thin needles into specific points on the body. Some studies suggest that acupuncture may help reduce pain and inflammation associated with pancreatitis.

Herbal Medicine:

Certain herbs, such as licorice root and chamomile, have been traditionally used to support digestive health. However, it’s crucial to consult with a healthcare provider before using any herbal remedies, as they can interact with medications.

Mind-Body Techniques:

Practices like meditation, yoga, and tai chi can help reduce stress and promote relaxation, which may indirectly benefit pancreatic health by reducing inflammation in the body.

Probiotics:

While research is ongoing, some studies suggest that probiotics may help support gut health and potentially reduce inflammation in the digestive system, including the pancreas.

When considering complementary therapies, it’s essential to:

Discuss all treatments with your healthcare provider to ensure they’re safe and appropriate for your condition
Choose qualified practitioners for therapies like acupuncture or herbal medicine
Be aware that complementary therapies should not replace conventional medical treatment
Monitor your symptoms and report any changes to your healthcare provider

By taking a holistic approach that combines conventional medicine with carefully selected complementary therapies, many individuals with pancreatitis find improved symptom management and overall well-being. However, it’s crucial to remember that what works for one person may not work for another, so a personalized approach is key.

Natural Treatment Remedies to Relieve Pancreatitis

Pancreatitis is a condition that is characterized by irritation or inflammation of the pancreas. The pancreas is located behind your stomach in the upper abdomen. Symptoms of pancreatitis include nausea and vomiting, abdominal pain that spreads to the back, and pain that occurs after eating a meal. Pain becomes constant once the problem passes into the chronic stage.

Symptoms of pancreatitis can be relieved by natural remedies. If you are suffering from pancreatitis pain, natural methods along with your medical treatment can bring you greater comfort and relief. Let’s talk about the natural treatment remedies that can relieve pancreatitis symptoms.

Turmeric

Turmeric contains curcumin, which is a powerful antioxidant that reduces inflammation and provides relief from the symptoms of an inflamed pancreas. It is recommended that pancreatitis patients take 500 to 700 mg of turmeric per day. Turmeric can be used in cooking rice or meat dishes, or mixed in with milk to make it more palatable.

Ginger

Ginger contains antioxidants that are good for the pancreas as they control inflammation and boost the enzymes needed for proper digestion. When brewed, ginger tea provides soothing effects for anyone experiencing pancreatitis symptoms such as pain and nausea. It can also be used in cooking soup dishes.

Ginger can provide relief from pancreatitis and also other gastrointestinal issues including stomach pain, heartburn, and acid reflux. Furthermore, ginger extract is in fact known for its anti-cancer properties and can be used as a preventive measure against pancreatic cancer.

Coconut Oil

If you have pancreatitis, avoid cooking with oils that can worsen inflammation. Coconut oil is rich in omega-6 fatty acids, which are very beneficial to those with inflammatory conditions. In addition, coconut oil contains medium-chain triglycerides (MCTs), which means it is not taxing on the pancreas to break down. Furthermore, coconut oil not only reduces inflammation but also boosts nutrient absorption. Coconut oil can be consumed on its own or used in cooking since it remains stable even at elevated temperatures.

Spinach

Vitamin deficiency can worsen symptoms of pancreatitis. In addition to being rich in antioxidants, spinach contains a number of vitamins that support the pancreas. Spinach contains vitamins A, B, C, and E, iron, and selenium, all of which benefit pancreas health.

Mushrooms

Mushrooms contain naturally occurring compounds that slow the progression of pancreatitis. Reishi mushrooms contain powerful anti-inflammatory agents and have an analgesic effect, which improves symptoms of pancreatitis. Terpenoids, which is a compound found in Reishi mushrooms, decreases COX-2 expression and inhibits prostaglandin E2 production, which eases pain and inflammation. In addition to Reishi mushrooms, Shiitake mushrooms and Maitake mushrooms also contain compounds that relieve inflammation in the pancreas and protect it.

An important part of pancreatitis treatment is making dietary and lifestyle changes that will help soothe symptoms. Before starting any natural treatment for pancreatitis symptoms, consult your physician.

Pancreatitis Treatment in Austin, TX

At Austin Gastroenterology, our gastrointestinal (GI) doctors are highly experienced in treating pancreatitis. The goal of treatment is to address the underlying issue, soothe symptoms, and restore pancreatic function. We will make personalized recommendations that can improve your quality of life.

Pancreatitis can be scary if you deal with it alone. At Austin Gastroenterology, our compassionate GI doctors support you throughout treatment and recovery. To schedule an appointment with one of our GI doctors, call our clinic nearest you or use our convenient appointment request form.

Pancreatitis Symptoms + 11 Natural Ways to Help

The symptoms of pancreatitis depend on whether it is an acute or chronic case. Acute cases come on rapidly and can be the result of heavy drinking, gallstones or even blunt force trauma from an accident. Acute pancreatitis can be life-threatening, but with proper medical intervention and treatment the majority of people recover. However, recurrences can happen and it is possible for acute pancreatitis to become chronic.

Diagnosing this condition requires a thorough examination and often multiple tests. The severity and the type will determine the course of action. For acute cases, a few days on clear liquids may resolve the problem, while more severe cases may require surgical intervention. For chronic pancreatitis, adjusting the diet and finding ways to manage the pain and discomfort is typical. However, antibiotics, IV hydration and nutritional support may be required.

Chronic: This form is incurable. The severity and frequency of chronic pancreatitis symptoms vary from person to person. Worsening symptoms are often linked to eating a large high-fat meal or drinking alcohol. As the disease continues to create scar tissue and damage the pancreas, the risk for certain conditions like diabetes and pancreatic cancer increases. In addition, the body can start to have a difficult time processing and absorbing nutrients causing vitamin deficiencies.

Childhood Pancreatitis: This condition is considered fairly rare and is most often found in children with cystic fibrosis or after a physical trauma. In some cases, the anatomy of the ducts in the liver or pancreas may cause this disease in children. Anti-seizure medications, certain antibiotics and chemotherapy may also cause childhood pancreatitis. However, in nearly one-third of cases a cause will not be identified. (6)

Autoimmune Pancreatitis: Sharing many of the same symptoms as both chronic and acute, here the inflammation is caused by the body’s immune system attacking the pancreas directly. This condition is broken into two types, Type 1 can affect multiple organs while Type 2 affects only the pancreas. Autoimmune pancreatitis is rare and newly-recognized disease that can be misdiagnosed as pancreatic cancer. (7)

Treatment protocols will be determined based on the type, the symptoms that are presenting, and the severity of symptoms. For acute cases, once hospitalized, fasting will provide the pancreas the opportunity to recover. Once the inflammation is under control, clear liquids and bland foods will be introduced. If inflammation persists, a feeding tube may be required to ensure that the patient is receiving adequate nutrition.

Vitamin D. Shows anti-proliferative effects and repression of cancer cells in the pancreas and, more importantly, a study has found that it reduces inflammation and fibrosis in pancreatitis. (21) With pancreatitis, try to get 15–30 minutes each day of sunshine, without sunscreen, to increase vitamin D levels in your body. In addition, focus on cold-water fish like halibut, mackerel and salmon in your diet.

5. Omega-3 Fatty Acids: Adding 1 to 2 tablespoons each day of a high-quality omega-3 fatty acid supplement is shown to reduce inflammation and improve immunity. In a meta-analysis published in the journal Nutrients, supplementation reduced the risk of mortality, infectious complications, and reduced the length of hospital stays for pancreatic patients. Authors encouraged large-scale multi-center randomized clinical trials. (22)

9. Reishi Mushroom. Used in holistic medicine practices, a recent study on chronic pancreatitis found that Ganoderma lucidum (the scientific name for reishi mushroom) increased the abundance of beneficial bacteria. And researchers noted this study shows potential for use of this mushroom as a possible therapy for chronic pancreatitis. Take 150 milligrams to 300 milligrams twice a day to help relieve inflammation while boosting immune system response. (27)

A special note on Ghrelin, Leptin and Melatonin. These three hormones are noted in research to significantly reduce the severity of pancreatitis symptoms and protect pancreatic tissue from inflammatory damage. Learning how to improve your levels of ghrelin and leptin can be helpful. Resist restricting calories, get plenty of sleep and manage stress, avoid processed foods and eat plenty of protein to optimize your levels. (30)

In recent years, there has been a steady upward trend in the incidence of acute pancreatitis (AP) [1, 2, 11, 23, 27, 31, 41, 43, 58]. Difficulties in differential diagnosis, increasing frequency of occurrence, severity of course, complexity of social and labor rehabilitation of patients who have undergone OP make the diagnosis, treatment and prevention of this disease among the most controversial and complex problems of modern medicine [8, 13, 21]. OP is 9-12.6% of all acute surgical diseases of the abdominal cavity and is characterized by a variety of clinical forms, the complexity of pathogenesis with the development of a specific enzyme toxemia syndrome and frequent postnecrotic purulent complications [3, 10, 19, 38, 42].

With the progress achieved over the past decades in the diagnosis and treatment of this disease, the results of treatment to date remain unsatisfactory. If the overall mortality is 2.6-9%, then with destructive forms of pancreatitis it reaches 40-70% [6, 16, 18, 24, 27, 46-48]. The remaining high mortality in AP determines the need to develop and implement more effective methods to improve treatment outcomes and accelerate the clinical rehabilitation of patients [5, 17, 23, 28, 34].

As an independent nosological form, OP is a polyetiological disease [4, 22, 28]. The causes contributing to the development of AP are alimentary factors (40%), acute diseases of the biliary tree (30%), pancreatic injuries (10%), etc. (20%) [2, 3, 8, 24, 32, 45, 55]. One of the leading causes of OP development is diseases of the biliary tract (cholelithiasis, choledocholithiasis, complicated by obstruction of the common bile duct and major duodenal papilla) [2, 3, 9, 18, 48].

A number of researchers who have studied the pathogenesis of OP indicate that the activation of lipases, in particular phospholipase A ₂, is of no small importance in its development [7, 9, 53, 56]. Along with this, the factor of the ratio between activated enzymes and their inhibitors plays an important role in the pathogenesis of the disease. According to other researchers, the leading cause in the pathogenesis of AP is a violation of microcirculation in the pancreas [12, 15, 33, 49, 55]. The authors believe that the result of impaired blood circulation in the gland is the further accumulation of metabolic products, increasing acidosis and hypoxia [28, 45, 50]. Developing tissue hypoxia in OP leads to activation of lipid peroxidation (LPO) processes in cells with inhibition of natural antioxidant defense [22, 40, 59] and a decrease in the level of bioenergetic processes in the cell [39]. With the predominant effect of proteolytic enzymes and biologically active substances, acinar necrosis is formed [18]. Non-viable tissues of the pancreatic parenchyma have the ability to quickly melt, forming a gray mass with a high content of proteolytic enzymes, which, entering the bloodstream, cause the development of a systemic inflammatory reaction and endogenous intoxication, which determine the severity of the disease [36, 52, 60]. Severe endogenous intoxication in OP explains the extremely serious condition of patients and death in the early stages after the onset of the disease [31, 33, 37].

Today, regarding the treatment of patients with OP, doctors consider it necessary to adhere to a reasonable combination of both conservative and surgical methods of correction, without opposing them [13, 27, 42, 43]. It is generally accepted that all patients with OP should first be treated conservatively. According to numerous researchers, in most cases, a set of conservative measures gives a positive effect, only 10-32% of patients undergo surgical interventions due to the progression of the inflammatory process in the pancreas [11, 30, 49]. Endogenous intoxication and oxidative stress arising from OP often progress even after surgery, forcing surgeons to look for additional ways to prevent these severe consequences. As a result, the search for new methods of treating patients with OP, including minimally invasive interventions, is relevant [57].

Functional rest of the pancreas can be achieved in two ways: by reducing the stimulating effects on the exocrine function and by affecting the acinar cells themselves [16]. An effective method for correcting enzyme-inhibitory imbalance in the blood is hemosorption using the Ovosorb duck protein sorbent, which is active against trypsin and other pancreatic proteolytic enzymes [21]. A new direction in the treatment of hyperenzymatic pancreatitis is the development of drugs – platelet activating factor antagonists. The representative of this group is lexipafant, which, according to foreign authors, is more effective than sandostatin in terms of reducing the number of complications, reducing mortality and terms of relief of pain in acute pancreatitis [29, 44].

Observations show that the treatment of OP cannot be successful without the inclusion of components that help reduce the activity of free radical processes and stimulate the body’s antioxidant system [12, 22]. Since the activation of the process of lipid peroxidation of biomembranes reduces the resistance of the cells of the body as a whole and the phenomena of endointoxication progress [36, 54, 58], the activation or direct use of antioxidant systems in the complex of therapeutic measures in OP becomes of fundamental importance, especially since the level of antioxidant activity of the pancreatic tissue one of the lowest in the body [35, 51, 59].

In their studies, J. Antosiewicz et al. [22] show that the use of antioxidants with different levels of impact on LPO processes, in particular the use of fat emulsions with preparations of unitiol and α-tocopherol, provided the most adequate protection of pancreatic cell membranes and the whole organism as a whole, preventing the progression of cellular disorders in patients with OP. [22]. Some authors point to the effectiveness of using ultraviolet blood irradiation [45], magnetic laser (MIL) therapy [44], and ozone therapy [14] in the complex treatment of OP. The development and improvement of the latest medical technologies has contributed to the widespread introduction into clinical practice of various methods of ozone therapy, which are currently successfully used in the treatment of a huge range of diseases, including a number of surgical ones [14, 25, 26]. Influencing almost all links of the body’s homeostasis, ozone affects both the cellular and molecular levels, as well as the organ and organism levels [14]. It has been proven that when high concentrations of ozonized solutions are used (by local action), powerful oxidizing properties of ozone are manifested, directed against microorganisms. It is important that ozone therapy not only has an anti-inflammatory property, but also improves microcirculation and reparative processes at the sites of ozonide application, stimulates the restoration of the adaptive-compensatory properties of subcellular structures [26]. Our experience in the use of ozone therapy in the treatment of a number of surgical diseases suggests that this method is able to influence the key links in the pathogenesis of systemic disorders in OP of various etiologies, including biliary etiology, and can be fully used in its complex treatment.

In recent years, lasers with magneto-infrared radiation have been used to improve the results of treatment of patients with OP [45]. Studies have shown that magneto-infrared laser radiation is characterized by such properties as temporal and spatial coherence, polarization, monochromaticity, power density and radiation energy. A decrease in general intoxication, an improvement in organ and peripheral hemoperfusion, and a rapid relief of clinical manifestations prove the effectiveness of using MIL therapy in the complex treatment of patients with OP [15].

Despite the fact that no one disputes the role of intraductal hypertension in AP of biliary etiology, the methods and timing of its elimination remain debatable. Some authors, if duodenoscopy does not reveal a stone wedged into the nipple of Vater to relieve hypertension, consider the formation of cholecystostomy to be optimal [2]. According to other recommendations, endoscopic retrograde cholangiopancreatography with possible endoscopic papillosphincterotomy is indicated only in patients with signs of obstructive jaundice and dilated bile ducts or if conservative measures have failed within 48 hours [11, 18, 57]. Other authors point out the need to perform endoscopic retrograde cholangiopancreatography followed by endoscopic papillosphincterotomy [11, 20, 47] as the first step in resolving biliary hypertension, which is often impossible in emergency surgery. The technical feasibility of performing endoscopic papillosphincterotomy is largely determined by the successful cannulation of the major duodenal papilla, which is possible in 65-86% of cases for the common bile duct and in 80-89% of observations for the pancreatic duct [19], which in turn depends on the possibility of “removing” its mouth opposite the distal end of the duodenoscope [20, 48].

The question of the expediency of surgical treatment in the enzymatic phase of OP is the subject of discussion among many generations of surgeons [3]. According to different authors, it makes no sense to operate on patients with severe OP at an early stage of the disease [2], since the results of treatment (overall mortality up to 30-50% and the incidence of purulent complications with or without surgery) will be the same [48]. So, V.I. Filin et al. [21] contraindications to surgery are:

Currently, direct indications for surgery are cholecystopancreatitis with increasing jaundice (destructive forms of cholecystitis, cholangitis, choledocholithiasis) [2, 3, 34, 48] and the ineffectiveness of conservative detoxification methods in the first 2-3 days of the disease [15]. A compromise between supporters of extremely radical surgical and conservative treatment was the combination of pathogenetically substantiated conservative therapy with elements of minimally invasive surgery (laparoscopy, laparocentesis) [20]. Laparoscopy allows assessing the degree of enzymatic “lesion” of the abdominal cavity, the state of the pancreas, draining the abdominal cavity and omental sac, and forming a cholecystostomy [11, 34]. The advantages of this intervention are low trauma and short duration [31]. The rational use of low-traumatic methods of treating OP is an urgent problem today, given that with such a disease as pancreatic necrosis, patients are admitted in a serious condition, most often caused by enzymatic, pancreatogenic shock. The implementation of any radical interventions in such a situation is accompanied by a high level of mortality. Low invasiveness and constantly growing possibilities of endovideosurgery make it possible to introduce new provisions in the tactics of managing patients with OP [20]. It is these aspects, in our opinion, that were the reason for the constantly growing number of publications in domestic and foreign literature devoted to this problem. In case of OP, some authors stop only at the diagnostic stage, urging, in case of detection of destructive changes in the parenchyma with effusion and spread of destruction to the parapancreatic tissue, to switch to laparotomy with subsequent drainage of the abdominal cavity, considering the indication for laparoscopic drainage only the presence of single foci of steatonecrosis and effusion not exceeding 200 ml [32].

The literature also contains information on the use of videolaparoscopic resection of the pancreas as a method of treating OP [20]. The authors believe that the optimal period for the use of endoscopic methods for the diagnosis and treatment of acute OP is the first 24 hours after the onset of clinical symptoms of the disease. The indication for combined endoscopic papillosphincterotomy is the presence of acute occlusion of the major duodenal papilla by gallstones with no bile flow into the duodenum [23, 31].

Thus, the study of modern literature showed that along with the successes achieved in the treatment of acute pancreatitis, there are a number of unresolved issues. Developing pancreatogenic toxemia leads to the development of endotoxemia with the appearance and growth of multiple organ failure syndrome affecting all organs and systems without exception [5, 8, 13, 23, 27, 45], which is one of the important reasons for poor treatment outcomes. In our opinion, the use of ozone therapy and antioxidants in the complex treatment of acute pancreatitis in combination with laser therapy will reduce the number of complications, reduce mortality and thereby improve the results of treatment. The foregoing determines the relevance of further study of the pathogenesis of acute pancreatitis and the search for effective methods for correcting emerging disorders of the body’s homeostasis.

In pancreatitis, patients complain of acute pain in the abdomen, more often in the left side of it, radiating to the back. Intoxication is expressed, which manifests itself in the form of nausea, vomiting, general weakness, fever, fever, loss of appetite. The stool is mushy, oily, contains undigested food particles. At the same time, certain types of pancreatitis can be almost asymptomatic for the patient, but digestive disorders are still present, which can be expressed in heaviness in the lower part of the stomach or slight numbness in this area after eating or alcohol.