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Barium solution: Barium Sulfate: MedlinePlus Drug Information

[New preparation method for barium enema: efficacy and administration of oral intestinal lavage solution with gastrointestinal prokinetic agent]

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. 2004 Jan;64(1):22-30.

[Article in

Japanese]

Shinichi Futei 
1
, Yoshinori Sugino, Sachio Kuribayashi, Yutaka Imai, Fumiaki Ueno, Toshifumi Hibi, Toru Mitsushima

Affiliations

Affiliation

  • 1 Department of Radiology, Keio University School of Medicine.
  • PMID:

    14994507

[Article in

Japanese]

Shinichi Futei et al.

Nihon Igaku Hoshasen Gakkai Zasshi.

2004 Jan.

. 2004 Jan;64(1):22-30.

Authors

Shinichi Futei 
1
, Yoshinori Sugino, Sachio Kuribayashi, Yutaka Imai, Fumiaki Ueno, Toshifumi Hibi, Toru Mitsushima

Affiliation

  • 1 Department of Radiology, Keio University School of Medicine.
  • PMID:

    14994507

Abstract

The modified Brown’s method is commonly used in Japan as preparation for barium enema; however, in a few cases, its cleansing effect is not satisfactory even with the use of adequate diet. To develop a new method of preparation for barium enema, we examined the use of an oral intestinal lavage solution (PEG-ELS) with mosapride and compared it with the modified Brown’s method. We administered mosapride and PEG-ELS by four different methods. These methods were assessed by the amount of remaining feces and the adequacy of barium coating. Methods in which mosapride was taken separately before and after the intake of PEG-ELS were more effective than the method using mosapride and the modified Brown’s method. Lesion detection was almost the same as that with the modified Brown’s method. In conclusion, preparation for barium enema using mosapride before and after PEG-ELS intake is more effective than the modified Brown’s method.

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Barium Enema: Purpose, Procedure & Risks

Barium Enema: Purpose, Procedure & Risks

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Medically reviewed by Deborah Weatherspoon, Ph. D., MSN — By Brian Krans — Updated on July 9, 2017

What Is a Barium Enema?

A barium enema is a type of X-ray imaging test that allows doctors to examine your lower intestinal tract. It involves delivering a contrast solution that contains the metallic element barium into your rectum while a technician takes X-ray images of the area. The barium solution will be delivered using an enema — a process in which your doctor pushes a liquid into your rectum through your anus.

The barium solution helps to improve the quality of the X-ray images by highlighting certain areas of tissue. The X-ray used in this procedure is known as fluoroscopy. It allows the radiologist to see your internal organs in motion by tracking the flow of the barium solution through your intestinal tract.

The test doesn’t require painkillers or sedation, but there may be moments of slight discomfort.

Your doctor may order a barium enema if they suspect an abnormality in your lower gastrointestinal (GI) tract. There are numerous conditions and symptoms that could prompt your doctor to examine your lower GI tract, including:

  • abdominal pain
  • blood in your stools
  • a change in your bowel movements
  • Crohn’s disease
  • chronic diarrhea
  • colorectal cancer
  • diverticulitis
  • irritable bowel syndrome
  • polyps
  • rectal bleeding
  • a twisted loop of the bowels (volvulus)
  • ulcerative colitis

Your doctor will ask you to cleanse your bowels the night before your test. This may include using laxatives or taking an enema at home.

You shouldn’t eat anything after midnight the night before your procedure. On the day of the procedure, you can drink clear liquids, such as water, tea, juice, or broth. This is to ensure that your colon is clear of any stool, which could show up in the X-ray images. Tell your doctor if you’ve been having problems with your bowel movements prior to the test.

A barium enema typically takes between 30 and 60 minutes and is performed at a hospital or specialized testing facility. You’ll change into a hospital gown and remove any jewelry or other metal from your body. Metal can interfere with the X-ray process.

You’ll be positioned on an exam table. X-rays will be taken to ensure that your bowels are clear. This may also involve a physical rectal exam.

The radiologist will then insert a small tube into your rectum and introduce the barium and water mixture. The radiologist may gently push air into your colon after the barium has been delivered in order to allow for even more detailed X-ray images. This is called an air-contrast barium enema.

The technician will instruct you to hold still and hold your breath while the X-ray images are taken. You’ll most likely be repositioned several times to take pictures of your colon from different angles. This may cause you some discomfort and cramping, but it’s typically mild.

If you’re having trouble keeping the solution in your colon, alert the technician.

After the procedure, the majority of the barium and water will be removed through the tube. The rest you’ll pass in the bathroom.

The results are typically categorized as negative or positive. A negative result means that there were no abnormalities found. A positive result means that abnormalities were found. This usually means that further testing will be required.

Your doctor will discuss your results with you and the next steps.

Any test involving radiation carries a slight risk of cancer, including X-rays. However, the benefit of an accurate diagnosis outweighs the risks from the small amount of radiation you’ll be exposed to during the test. Remember that many things you do regularly, such as flying in an airplane, expose you to much more radiation than an X-ray.

If you are pregnant or believe you may be pregnant, tell your doctor. X-rays are not recommended for pregnant women because the radiation could harm your unborn child.

If it’s possible you have a tear, also called a perforation, in your colon, your doctor may opt for a contrast solution with iodine in it. This solution causes fewer potential complications if it leaks out of your colon.

The most common risk of a barium enema is an allergic reaction to the barium solution. Tell your doctor about any allergies you have.

Other rare complications from a barium enema may include:

  • inflammation of the tissues around your colon
  • obstruction of your gastrointestinal tract
  • a perforated colon
  • a tear in your colon wall

After the exam you can go about your day as you normally would. You may resume a normal diet but you should drink lots of water and increase your fiber intake. This means increasing how much water you drink and eating foods like whole-wheat pasta, beans, peas, and raspberries. Sometimes a laxative is needed to help remove the barium.

For a few days after the procedure, you may notice that your stools are white or lighter in color than normal. This is caused by the barium and is considered normal. Your rectum and anus may be sore from the procedure.

If you have difficulty or pain with bowel movements, fever, or rectal bleeding, call your doctor. If you do not have a bowel movement for two days after the exam or are unable to pass gas, call your doctor.

Last medically reviewed on January 14, 2016

How we reviewed this article:

Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.

  • Barium Enema. (n.d.)
    hopkinsmedicine.org/healthlibrary/test_procedures/gastroenterology/barium_enema_92,P07687/
  • Barium Enema Examination. (n.d.)
    asrt.org/docs/default-source/patientpages/barenema_papg.pdf
  • Mayo Clinic Staff. Barium enema. (2011, June 18)
    mayoclinic.com/health/barium-enema/MY00619
  • Radiation exposure during commercial airline flights. (n.d.)
    hps.org/publicinformation/ate/faqs/commercialflights.html

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Medically reviewed by Deborah Weatherspoon, Ph.D., MSN — By Brian Krans — Updated on July 9, 2017

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Barium sulfate for fluoroscopy – instructions for use, doses, side effects, reviews of the drug:

0.002 ‰

Analogs

All forms of release, dosages, registration certificates, drug manufacturers, drug characteristics

Barium sulfate for fluoroscopy (powder for suspension for oral administration), instructions for medical use RU No. Р N000252/01

Last modified: 08/15/2017

Contents

  • Active substance
  • ATX
  • Pharmacological group
  • Dosage form
  • Compound
  • pharmachologic effect
  • Description of the dosage form
  • Pharmacokinetics
  • Pharmaco-therapeutic group
  • Indications
  • Contraindications
  • Use during pregnancy and lactation
  • Dosage and administration
  • Side effects
  • Interaction
  • special instructions
  • Release form
  • Terms of dispensing from pharmacies
  • Storage conditions
  • Best before date
  • Reviews

Active ingredient

Barium sulfate

ATX

V08BA02 Barium sulfate without suspending agent

Pharmacological group

Radiocontrast agents

Dosage form

Powder for oral suspension.

Composition

The active ingredient in is barium sulfate.

Radiocontrast agent. Envelops the mucous membrane of the digestive tract and provides a clear image of the microrelief of the mucous membrane. Increases image contrast in x-ray studies of the gastrointestinal tract. The maximum contrast of the esophagus, stomach and duodenum is achieved immediately after oral administration, the small intestine – after 15–90 min (depending on the rate of gastric emptying and the viscosity of the drug). The greatest visualization of the distal small and large intestine depends on the position of the body and hydrostatic pressure.

Description of dosage form

White or almost white, fine, odorless loose powder.

Pharmacokinetics

Low toxicity. It is not absorbed from the gastrointestinal tract and does not enter the systemic circulation. Completely excreted through the intestines after 24-48 hours.

Pharmacotherapeutic group

Radiocontrast agent.

Indications

X-ray examination of the pharynx, esophagus, stomach and intestines (including double contrast method).

Contraindications

Hypersensitivity; violation of the integrity of the walls of the gastrointestinal tract (suspicion of it), esophagotracheal fistulas; swallowing disorder, intestinal obstruction, constipation, stenosis of the esophagus, bleeding from the organs of the gastrointestinal tract; condition after surgical interventions on the organs of the gastrointestinal tract; malabsorption syndrome, food allergy.

With caution

General serious condition of the patient; bronchial asthma.

Use during pregnancy and lactation

Not recommended during pregnancy. If it is necessary to conduct a study during lactation, breastfeeding should be stopped within 24 hours after the study.

Dosage and administration

Information for healthcare professionals only.
Are you a healthcare professional?

Inside, for x-ray examination of the pharynx, esophagus, stomach and small intestine: barium sulfate for fluoroscopy is used in the form of an aqueous suspension prepared immediately before the x-ray examination. To prepare a suspension from a powder, mix it with warm boiled or distilled water in a ratio of 2:1 to 4:1 for adults and from 1:1.5 to 1:2 for children and mix thoroughly for 4-5 minutes (possibly with using a mixer), the dose for adults per study is 300 ml, for children – 50-100 ml.

Side effects

Allergic reaction, constipation; isolated cases of the so-called “barium” appendicitis are described.

When using gas-forming substances in the process of double contrasting – discomfort in the epigastric region.

Interactions

Information for healthcare professionals only.
Are you a healthcare professional?

Not marked.

Special instructions

For double contrasting in adults and older children (double contrasting is not advisable in younger children), immediately before the examination, the patient is given, depending on age, 1.5–3.5 g of baking soda (in solution or powder), which is quickly washed down with a solution of 1-3 g of citric acid. The total volume of distilled water should not exceed 7–15 ml. Can be used to study intestinal motility in children. After oral administration, the suspension passes through the small intestine in children in 1-2 hours, which makes it possible to study the structure and motor function of the small intestine in a short time and, thereby, to abandon the special methods of its study. The duration of the passage of the suspension through the colon is 4 hours, which significantly reduces the time of inspection of the intestine and reduces the radiation exposure by 2 times.

Presentation

Powder for suspension for oral administration.

100 g in plastic cups. Each cup is hermetically sealed with an aluminum foil lid.

A cup with the drug, together with instructions for use, is placed in a cardboard box.

For inpatient use, drug cups are placed in cartons of 10, 20, 30, 40, 50, 60, 90, or 120 pieces, along with the appropriate number of instructions for use.

Terms of dispensing from pharmacies

At the request of medical institutions.

Storage conditions

Store in a dry place.

Keep out of reach of children.

Shelf life

5 years.

Do not use after the expiry date which is stated on the packaging.

Update date: 03/24/2023

Reviews



Read all reviews and leave your own.

Information for healthcare professionals only.
Are you a healthcare professional?

instructions for use, price, analogues, composition, indications

active substance – barium sulfate.

White or almost white, fine, odorless powder.

Radiopaque agent. Envelops the mucous membrane of the digestive tract and provides a clear image of the microrelief of the mucous membrane. Increases image contrast in x-ray studies of the gastrointestinal tract. The maximum contrast of the esophagus, stomach and duodenum is achieved immediately after oral administration, the small intestine – after 15-90 min (depending on the rate of gastric emptying and the viscosity of the drug). The greatest visualization of the distal small and large intestine depends on the position of the body and hydrostatic pressure.

Low toxicity. It is not absorbed from the gastrointestinal tract and does not enter the systemic circulation. Completely excreted through the intestines after 24-48 hours.

Used as a radiocontrast agent for visualization of the upper gastrointestinal tract (esophagus, stomach, duodenum) both by conventional X-ray and by double contrast.

Hypersensitivity; violation of the integrity of the walls of the gastrointestinal tract (suspicion of it), esophagotracheal fistulas; swallowing disorder, intestinal obstruction, constipation, stenosis of the esophagus, bleeding from the organs of the gastrointestinal tract; condition after surgical interventions on the organs of the gastrointestinal tract; malabsorption syndrome, food allergy; atresia; ischemic and necrotizing enterocolitis; injury or chemical burns of the gastrointestinal tract.

Carefully.

The general serious condition of the patient; bronchial asthma, dehydration.

Not recommended during pregnancy. If it is necessary to conduct a study during lactation, breastfeeding should be stopped within 24 hours after the study.

Inside, for x-ray examination of the pharynx, esophagus, stomach and small intestine: barium sulfate for fluoroscopy is used in the form of an aqueous suspension prepared immediately before the x-ray examination. To prepare a suspension from a powder, mix it with warm boiled or distilled water in a ratio of 2:1 to 4:1 for adults and from 1:1.5 to 1:2 for children and mix thoroughly for 4-5 minutes (possibly with using a mixer), the dose for adults per study is 300 ml, for children – 50-100 ml.

From the digestive system: barium appendicitis, constipation; at

the use of gas-forming substances in the process of double contrasting – discomfort in the epigastric region.

Allergic reactions: urticaria, erythema, rash.

Barium sulfate is biologically inert and does not interact with other drugs. However, the presence of barium sulfate in the gastrointestinal tract may affect the absorption of other drugs taken at the same time.

Influence on the ability to drive a car or other mechanisms

Does not affect.

– The drug should be taken under medical supervision.

– Do not use in patients during and up to 4 weeks after radiotherapy to the rectum or prostate.

– After using barium sulfate to prevent constipation, it is recommended to drink an increased amount of fluid.

– Caution should be exercised when using barium sulfate in children, elderly and debilitated patients

– For double contrasting in adults and older children (double contrasting is not advisable in young children), immediately before the study, the patient is given, depending on age, 1.5-3.5 g of baking soda (in solution or powder), which quickly washed down with a solution of 1-3 g of citric acid.