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Hot flashes from birth control: I’m having hot flashes. Does it mean I’m starting menopause?

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I’m having hot flashes. Does it mean I’m starting menopause?

by Rachel Burt, Women’s Health Nurse Practitioner at Roswell OB/GYN…………………………………

We all know hot flashes and night sweats are very common symptoms of menopause.  But, a new study by The North American Menopause Society (NAMS) suggests many young premenopausal women have hot flashes too.  I often have women in the thirties and forties complain of night sweats or hot flashes.  Typically, they come to our office concerned their hot flashes are a sign of early menopause.  In some cases, premature menopause is the culprit of the internal thermoregulation changes.  However, other times it may be completely unrelated to menopause.

The new study released by NAMS found 55 percent of women age 45 to 56 years old with regular menstrual cycles reported night sweats or hot flashes.  Asian and Hispanic women were less likely to report symptoms, while Native Americans and black women were the most likely to report hot flashes.   Women reporting hot flashes were more likely to be taking soy supplements than those not reporting hot flashes.

There are some common reasons for hot flashes or night sweats in young women.  If you are experiencing these symptoms, try to track when they occur in your cycle.  We have a drop in estrogen levels a few days prior to our periods.  It is common to have hot flashes those few days before you start bleeding.  Women on birth control pills often have hot flashes the week of their placebo pills.  The active pills in the birth control pack have estrogen whereas the placebos do not.  During the placebo week, some women experience hot flashes as a response to the estrogen withdrawal.  The hot flashes should resolve once you start back on the active pills. It is also very common to have night sweats in the postpartum period.  The hormone fluctuations after delivering a baby may cause night sweats that resolve with time.

If you are having night sweats or hot flashes, I recommend you speak with your healthcare provider.   Often these symptoms are normal, but your provider may decide to draw some blood work to confirm.

If you have any questions, please contact your healthcare provider and schedule an appointment at 770 751 3600 or online athttps://secure.awhg.org/rosobgyn/

When Is It Time to Quit?

Medically reviewed by Sophia Yen, MD, MPH – Written by Pandia Health Editorial Team. Updated on March 1, 2021

Menopause and Birth Control: When Is It Time to Quit?

Menopause can be a distressing, confusing time for many women. It’s a natural part of life, but the timeline may vary between individuals with a uterus. You may have several questions about what this process entails, which is totally normal! The following article will provide some insight, particularly in terms of how to manage birth control use as you approach menopause.

What is menopause? 

The National Institute of Health (NIH) defines menopause as “a point in time 12 months after a woman’s last period. ” This is commonly experienced between the ages of 45 and 55 and can last anywhere from seven to 14 years. During this time, the body’s production of estrogen and progesterone (a.k.a the female hormones) decreases.

Menopause is often incorrectly used interchangeably with “perimenopause,” which refers to the early stages of the menopausal process. However, a person with a uterus has only officially reached menopause one year after their last period.

What is the difference between menopause and perimenopause?

Perimenopause is the time when the reproductive hormones first start to change. While periods continue during this time, they typically become irregular (i.e. a period may not occur every month) as the production of estrogen and progesterone slows down. Additional symptoms may occur, though some individuals report feeling normal during perimenopause. With that said, it is always a best practice to consult with a doctor if you notice any abnormal changes in your body.

In contrast, menopause is marked by the final period a woman has. If a person with a uterus has gone 12 months without a period they have gone through menopause. Their life after that 12 months is considered postmenopausal.

How long does perimenopause last?

The average length of perimenopause is four years. With that said, it may only last a few months for some or up to 10 years for others, though this is rare. An individual can know that they have completed perimenopause once they have gone 12 months without getting a period.

What are the symptoms of perimenopause?

Although menopause is a normal, healthy part of life for individuals with a uterus, it typically entails symptoms that can become unpleasant. Some individuals may not notice any significant changes, but many will likely experience one or more of the following:

  • Hot flashes and night sweats = a sudden feeling of warmth that spreads over the body
  • Breakthrough bleeding and spotting = bleeding when not on your period 
  • Irregular periods = inconsistent timing and heaviness of periods 
  • Headaches and/or migraines = pain that occurs in one or more regions of your head
  • Mood swings = intense and sudden changes in mood 
  • Insomnia = persistent difficulty falling or staying asleep 
  • Urine urgency and/or leakage = constantly feeling the need to go pee 
  • Vaginal dryness = lack of lubrication in the vagina 
  • Acne = blemishes (i. e. white heads and black heads) that pop up on the skin
  • Fatigue = feeling more tired than usual 
  • Breast tenderness = sore and/or swollen breasts 
  • Lower sex drive = lack of desire to have sex and/or pain during sex

Sometimes, the symptoms of perimenopause can cause significant problems in day-to-day functioning. Fortunately, there are various treatments that can be implemented to help provide some relief.

When should you see a doctor about perimenopausal symptoms?

While experiencing some symptoms is normal and common, a person with a uterus should consult a doctor if their daily life is negatively impacted. It is possible that their experience is solely related to perimenopause, but it could also be the result of other, more serious conditions such as fibroids, pregnancy, blood clotting disorders, or even cancer. Furthermore, speaking with a doctor is necessary in order to ensure that symptoms are caused by menopause and not something else.

The following symptoms may warrant a trip to the doctor

  • Very heavy periods with blood clots.
  • Periods that last much longer than usual.
  • Periods that occur more frequently than normal
  • Breakthrough bleeding between periods.
  • Spotting and/or pain after intercourse.

Can women get pregnant even if they’re perimenopausal?

Tldr: yes! 

Despite declines in fertility during perimenopause,  it is still possible to become pregnant. Even when periods become less frequent, the body may be releasing more eggs. Furthermore, if a person with a uterus is currently taking birth control, they should continue to do so during perimenopause. If they are not on birth control, they should use an additional form of contraception (i.e. condoms) for protection. It is also necessary to keep track of menstrual cycles in order to determine when it has been 12 months since the last cycle. Scheduling regular gynecological visits is a great way to help ensure that any rogue pregnancies will be detected early.

How does birth control affect perimenopause symptoms?

Hormonal birth control (i.e. the pill, patch, ring, IUD, etc.) can help prevent pregnancy and eliminate period symptoms. Similarly, using birth control during perimenopause can help alleviate unpleasant symptoms and even decrease the likelihood of negative health conditions. For instance, the process of menopause may lead to osteoporosis and other bone-related issues, and implementing birth control can help reduce this risk. Additionally, because birth control regulates hormone levels, it can further minimize some of the effects associated with perimenopause such as hot flashes, acne, and vaginal dryness.

It is important to note, however, that hormonal contraceptives can mask perimenopause symptoms. Furthermore, those who take birth control may not recognize when they have reached the perimenopause stage. For this reason, it is crucial to communicate with a doctor in order to better understand what is going on in your body.

When should women not take birth control pills for perimenopause?

While hormonal birth control can be extremely beneficial, it can increase the risk of blood clots in some individuals with a uterus. More specifically, it is recommended that those with a history of blood disorders, heart disease, and/or cancer (either in their family or personally) stop taking hormonal contraceptives as they enter their late forties. This also applies to individuals who smoke.

Instead of using high-dose hormonal birth control (which can increase the likelihood of developing blood clots) to alleviate the symptoms of perimenopause, individuals with a uterus can try hormone therapies or low-dose birth control pills. With that said, there are pros and cons to these methods, so individuals should consult a doctor in order to determine the best path for their lifestyle.

How can perimenopausal women benefit from low-dose estrogen birth control?

Low-dose birth control can be implemented both to prevent pregnancy and alleviate symptoms of perimenopause. Although low dose birth control is typically not recommended for individuals under the age of 30 because it can decrease bone density, it may have the opposite effect for those going through perimenopause. This is especially important, as the risk of osteoporosis increases with age. Low dose birth control may also be implemented to help prevent ovarian and uterine cancers.

How can I tell if I’ve reached menopause?

The average age of menopause is around 51 years old. Once an individual with a uterus has gone 12 months without a period, they have reached menopause. However, this may be difficult to track if the individual is taking hormonal birth control. Some may choose to stop birth control once they start to notice symptoms of perimenopause for this reason, but this does not have to be the case for all individuals. If one does choose to stop taking birth control, they should use another form of contraception (i.e. condoms) to prevent pregnancy. 

What’s the takeaway?

While menopause may seem like a scary thing to tackle, it is a natural part of life that occurs in all women with a uterus. Thankfully, several methods can be implemented to make the process a little easier. So rather than feeling doomed or ashamed if you are approaching the age of menopause, you might as well embrace it! 

How can Pandia Health help? 

Pandia Health makes accessing birth control easier than ever! Sign up for our FREE delivery service to get your prescription sent right to your mailbox. You can also schedule an online consultation with one of our expert doctors if you live in AZ, CA, CO, FL, GA, IL, MI, NV, TX, TN, PA, WA, or WY.

With Pandia Health, you can #SkipTheTrip to the pharmacy and feel confident that you will never run out of birth control on our watch. 

Frequently Asked Questions 

Can birth control cause hot flashes?

While birth control is typically not associated with hot flashes, if you do notice temperature fluctuations after starting a new prescription, consult a doctor to determine whether it may be a good idea to switch. Low-dose birth control may actually be implemented for those going through perimenopause as a means to reduce the severity of hot flashes. 

Do birth control pills delay menopause? 

Birth control pills have not been found to delay menopause. 

Do I need birth control after 45?

This depends on whether or not you have reached menopause. If you are still in the perimenopause stage, you can keep taking birth control in order to prevent pregnancy and reduce symptoms. 

Can birth control cause night sweats?

Night sweats may occur as a result of starting a new birth control prescription. However, this will not be the case for everyone. 

Does birth control help regulate periods?

Yes! Birth control stabilizes the female hormones, estrogen and progesterone, in order to create more regular cycles. It is also possible to skip your period while on birth control by skipping the row of sugar pills. 

Can perimenopause mimic pregnancy symptoms?

Perimenopause symptoms such as nausea, weight gain, and hot flashes can mimic those associated with pregnancy. With that said, it is important to take note of what is going on in your body and consult a doctor if you notice any changes. 

What age should you stop taking birth control pills?

This can vary depending on when an individual wants to get pregnant and/or starts to experience perimenopause symptoms. Consult a doctor if you are considering stopping your current birth control. 

How long does perimenopause last?

Perimenopuse typically lasts anywhere between a few months and four years. 

Can periods restart after menopause?

Periods do not restart after menopause. If you do experience vaginal bleeding after you have gone through menopause, consult a doctor. 

How long is too long for a period during perimenopause?

While this may vary in each individual with a uterus, most periods that occur during perimenopause should not last more than seven days. 

How long does a woman go through menopause?

The entire process of menopause (perimenopause, menopause, and post-menopause) typically lasts between 7 and 11 years, though it may be more or less for some.

 

Disclaimer: The views expressed in this article intend to inform and induce conversation. They are the views of the author and do not necessarily represent the views of Pandia Health, and are for informational purposes only, even if and to the extent that this article features the advice of physicians and medical practitioners. This article is not, nor is it intended to be, a substitute for professional medical advice, diagnosis or treatment, and should never be relied upon for specific medical advice.

Using the Pill to Treat Menopause – Menopause Center

While the main reason to take birth control pills is to prevent pregnancy, it turns out that the Pill can also act as a treatment for women approaching menopause — the time period called perimenopause — to manage irregular periods, hot flashes, and night sweats.

Birth control pills contain various combinations of the hormones estrogen and progesterone and are designed to shut down ovulation so that you don’t release a monthly egg and can’t get pregnant.

“As women age, the balance between the pituitary gland that excretes follicle stimulating hormone (FSH), and the ovary that excretes estrogen is all over the place,” says Robert S. Wool, MD, an ob-gyn at Noble Hospital, Mercy Medical Center, and Baystate Medical Center and in private practice in Westfield and Springfield, Mass. “Women may be making estrogen, but not usually cycling. Birth control pills will quiet the wildness of the reproductive cycle in a perimenopausal woman.”

It is important to note that, once you reach true menopause, you’ll stop taking the Pill — there’s no longer the need to suppress ovaries once they’re no longer active. If you’re still experiencing unpleasant symptoms, hormone replacement therapy, which uses smaller doses of hormones, might be an option, though you’ll want to discuss the risks with your doctor.

The Pill: Pros and Cons

Generally, birth control pills can bring relief for many perimenopausal women experiencing hot flashes or irregular periods, or both. If you and your doctor choose the birth control pill as a treatment for perimenopause, a low-dose type is best — usually 20 micrograms of ethinyl estradiol or less, but it may take some trial and error to find just the right dosage.

The Pill isn’t appropriate for every woman, however. “Women over age 35 who smoke are not good candidates to take birth control pills,” says Julia Schlam Edelman, MD, author of Menopause Matters: Your Guide to a Long and Healthy Life. “Smokers are at higher risk for getting a heart attack or stroke if they are over age 35 and take birth control pills.” Women with high blood pressure, who have had a blood clot in their leg, lung, or pelvis, who have had breast cancer, or who have liver disease also should not use birth control pills.

While the benefits of taking birth control pills may include relief of perimenopause symptoms like hot flashes and irregular cycles, there can also be the typical side effects of oral contraceptives, such as irregular bleeding (especially in the first few months), nausea, puffiness, and weight gain (though many low-dose oral contraceptive pills are weight neutral), says Charla Blacker, MD, a reproductive endocrinologist at Henry Ford Hospital in Detroit. “Mood swings usually are improved. However, occasionally, women report more depression with birth control pills. If a woman did not tolerate birth control pills during her early reproductive years, she may not tolerate them well in perimenopause.”

Also, women should be aware that birth control pills are not the fountain of youth. “Birth control pills can mask and treat symptoms,” says Dr. Wool, “but they do not alter the aging process.” Menopause will still occur when nature intends, although if a woman continues on perimenopausal birth control pills, she may not realize exactly when she has passed into menopause. In that situation, after stopping the pills, she will no longer menstruate and may begin to have hot flashes that were previously masked.

Ultimately, whether to use the Pill for perimenopause symptoms is a decision that should be made by you and your doctor. Each woman’s situation is different and there is no one-size-fits-all solution.

How do I know I’ve reached menopause if I’m on the pill?

You cannot know for sure you’ve reached the menopause when you’re on the pill. This is because hormonal contraception can affect your periods.

Menopause (when your periods stop permanently and you’re no longer fertile) is usually diagnosed:

  • if you’re over 50 and have not had a period for more than 12 months
  • if you’re under 50 and have not had a period for more than 2 years

These rules do not apply if you’re taking hormonal contraception.

In younger women, there are other reasons (apart from early menopause) why periods might stop, so discuss this with a healthcare professional if you’re worried.

Bleeding if you’re on the pill

If you’re taking the combined pill, you’ll have monthly period-type bleeds for as long as you keep taking the pill.

If you’re taking the progestogen-only pill, your bleeds may be irregular or stop altogether for as long as you keep taking the pill.

The combined pill may also mask or control menopausal symptoms, such as hot flushes and night sweats.

These factors can make it hard to know when you’re no longer ovulating and therefore no longer fertile.

No menopause test

There is no test that can tell for certain whether you’re in the menopause and can stop contraception.

There is a blood test to measure levels of follicle stimulating hormone (FSH) that can indicate if a woman is becoming menopausal. But this is not a useful test in women over 45 as FSH levels naturally go up and down at this time.

The FSH test is also not a reliable indicator that ovulation has stopped if a woman is taking the combined pill. It can be a helpful guide for women over 50 who are taking the progestogen-only pill.

Stopping contraception

All women can stop using contraception at the age of 55 as getting pregnant naturally after this is very rare. For safety reasons, women are advised to stop the combined pill at 50 and change to a progestogen-only pill or other method of contraception.

It is sensible to use a barrier method of contraception, such as condoms, to avoid getting sexually transmitted infections (STIs), even after the menopause.

Find local contraception services.

Page last reviewed: 1 July 2020

Next review due: 1 July 2023

Birth Control For Perimenopause In Low Doses

“Hot flashes, night sweats, anxiety, headaches, menopausal acne, joint pain, and brand-new belly fat during menopause? Woot! BRING IT ON!” said no woman. EVER.

And yet, if we are fortunate to live long enough, we women are guaranteed to go through menopause at some point along the way, and many of us will endure at least some of these of these symptoms at perimenopause and menopause.

Erratic and dropping estrogen is the primary culprit behind many menopause symptoms. Before reproduction shuts down for good at around age 51, rises and dips in hormone levels are responsible for the emotional and physical roller coaster ride many women experience, starting as early as their mid-30s.

The Effectiveness of Birth Control Pills

One way to manage many perimenopausal symptoms may be a treatment you thought you were done with: the Pill. * Because hormonal birth control provides estrogen at an even, predictable rate, the Pill can smooth the dips and peaks of fluctuations and balance out the hormones you’re losing.

For many women, hormonal birth control is an escape (maybe temporary and incomplete, but still an escape) from some of the more disruptive symptoms of perimenopause and menopause. If you’re having a hard time of it, and are a good candidate for hormonal birth control (no abnormal clot risk, not a smoker, etc.), a few years on the Pill might be a good way to go.

Why should you use birth control pills for perimenopause?

NOTE: As Dr. Sherry told us about birth control delaying menopause, if you’re still having periods, erratic or otherwise, you can still get pregnant. So if you engage in intercourse with men, some sort of birth control is called for. After teens, perimenopausal women have the second highest rate of unintended pregnancies. Remember, however, that the Pill does NOT reduce your risk of sexually transmitted diseases like herpes, so please continue to use condoms.  

The Pluses

Low-dose birth control pills can help ease the perimenopause transition for many women by regulating hormones. This can reduce hot flashes, ease mood swings, lessen the menstrual flow, regulate erratic periods, and lessen the impact of endometriosis. According to Harvard Health, birth control pills may also reduce vaginal dryness and prevent bone loss, all while protecting you from endometrial and ovarian cancers and those unintended pregnancies. And, WebMD adds, low-dose birth control pills may also help stave off colorectal cancer.

Want to try birth control for menopause symptoms/ A Gennev menopause-certified gynecologist can give you a trusted opinion, determine if medication is right for you, and they can provide prescription support. Book an appointment with a doctor here.

Risks of low-dose birth control?

Because the amount of hormones is so low, and because current formulations of the Pill are safer than previous versions, there are fewer side effects and risks to fear. Studies show low-dose birth control doesn’t cause weight gain, and vascular issues like deep-vein thrombosis and stroke aren’t generally an issue for women over 35 who don’t smoke.

The Minuses: The risk of increased breast cancer is still a subject of some debate, particularly when it involves women who are older (possibly because they started with the riskier, higher-dose oral contraceptives that were available when they were younger) or who have a family history of breast cancer.

Migraines may worsen with hormonal birth control, and the possibility of blood clots does still exist for some. Pills containing estrogen are not advised for those at risk of cardiovascular disease or hypertension or for those who smoke. Finally, research is being done to determine if birth control pills contribute to vaginal atrophy and painful sex.

[stay tuned for an upcoming podcast with Rachel Gelman, DPT, PT, of the Pelvic Health and Rehabilitation Center
on the effects of birth control]

And because the rates of STDs among the over-50 crowd are increasing (thanks, perhaps, to the advent of that little blue pill), we’ll remind you again: the Pill does not protect against sexually transmitted diseases such as herpes, gonorrhea, genital warts, or HIV.  Continue to use a barrier method such as condoms to reduce your risk of an STD.

When can I go off birth control?

Because the Pill can mask menopause symptoms – including causing “withdrawal bleeds” during the sugar-pill week – a woman on mixed-hormone oral contraception may not know she’s completed the transition to menopause. There are many hormone menopause tests availble. Getting an FSH (follicle-stimulating hormone) test during a break from taking the Pill may help a woman and her OB/GYN determine where she is in her menopause journey. The Gennev Menopause Assessment can also help her determine her place in the perimenopause to menopause transition during this break.

When a woman goes off the Pill to get a sense of her cycles (or lack thereof), some research indicates that may be a good time for her to transition from oral contraceptives to HRT (hormone replacement therapy), if she decides to go that route.

There are natural ways to manage menopause symptoms that are highly effective for some women. There are lifestyle choices or foods to eat for a healthier gutthat can make life during this challenging time easier for others. If you prefer not to take the hormonal route, or can’t because of an increased risk of breast or other cancers, you’re not out of luck. We highly recommend you talk with a Gennev Health Coach/Dietitian. Our coaches get special training in ways to mitigate menopause symptoms through nutrition, exercise, stress management, sleep hygiene strategies and more. 

You can book 30 minutes for your personal consultation with a health coach.

Do your research on low dose birth control pills

And for some women, there are birth control pills. There are risks to oral contraceptives, higher for some women than others, so please – do your research, talk to your doctor or one of ours, to make sure the information you’re getting is recent and reliable.

But as always, there is no need (and no medal that we know of) for suffering in silence. Reach out and talk with a menopause doctor OB/GYN or Health Coach at our menopause clinic  to find the solution that works best for your lifestyle, medical history, and current situation.

We’d love to know what you’re doing to make perimenopause/menopause more comfortable. Fill us in in the comments below, or share on the Gennev Facebook page or in Midlife & Menopause Solutions, the closed Gennev Facebook group.

*The information in this blog is for educational purposes only. To understand your potential risks and benefits, talk to a doctor.

 

Contraception: You Need It Longer Than You May Think, Sexual Side Effects of Menopause

Although fertility falls during perimenopause, women are not fully protected from an unplanned pregnancy until they have reached menopause, which means 12 straight months without a period. Even if you have a few months without a period, you can still get pregnant.

The bottom line is that you need to use an effective, safe, and appropriate method of birth control until menopause is confirmed if you don’t want to get pregnant at midlife.

Many choices for the midlife woman. Perimenopausal women can choose from a number of effective birth control options:

You need to use an effective, safe, and appropriate method of birth control until menopause is confirmed if you don’t want to get pregnant at midlife.

  • Hormonal oral contraceptives, such as combined estrogen-progestogen or progestogen-alone pills
  • Non-oral hormonal contraceptives, delivered by injection, skin patch, or vaginal ring
  • Intrauterine devices (IUDs) with or without hormones
  • Sterilization (tubal ligation or fallopian tube implants for women; vasectomy for men)
  • Barrier methods (diaphragm plus spermicide, spermicide-containing sponge, spermicide alone, male and female condoms), although
    these require disciplined use to be effective.

Natural family planning (the rhythm method) is not recommended for perimenopausal women because irregular periods make predicting ovulation difficult. Emergency contraception (one of the “morning-after” pills that actually can be used up to 72 hours after intercourse) is also available to provide backup after a contraceptive failure, but it is not recommended as regular birth control.

Remember that only one form of birth control—condom use—provides some protection against HIV and other sexually transmitted infections.

Special considerations for hormonal contraceptives. There are several things about hormonal contraceptive use that are particularly pertinent for perimenopausal women:

  • Hormonal oral contraceptives can provide a number of benefits for perimenopausal women beyond preventing pregnancy. These benefits, listed in the table at the bottom of the page, may also apply to non-oral hormonal contraceptives, although more study is needed to be sure.
  • In addition to potential benefits, use of hormonal contraceptives by perimenopausal women has been associated with an increased risk of blood clots and may be associated with some increase in the risk of heart attack, stroke, and breast cancer.
  • Perimenopausal women should not use estrogen-containing contraceptives if they smoke or have a history of estrogen-dependent cancer, heart disease, high blood pressure, diabetes, or blood clots. Otherwise, hormonal contraceptives appear to be safe for healthy women over age 35, provided they do not smoke.
  • Taking hormonal contraceptives can mask signs of approaching menopause, including menstrual irregularities. This can make it difficult to know when perimenopause is occurring.
  • Use of any combination estrogen-progestogen contraceptive will result in withdrawal bleeding (ie, bleeding like a menstrual period) even after menopause.
  • Some providers tell women to stop hormonal contraceptives at age 51 (the average age when menopause occurs), but this strategy is not always appropriate, since not all women will have reached menopause by that age and will still need birth control.
Benefits of hormonal oral contraceptives beyond birth control
More regular menstrual cycles
Reduced menstrual bleeding (and lower rates of iron deficiency anemia as a result)
Decreased uterine pain during menstruation
Decreased risk of ovarian and uterine cancer
Reduced hot flashes
Maintenance of bone strength
Improvements in acne (which can flare up around menopause)
 
Adapted from Menopause Practice: A Clinician’s Guide, 4th ed. Copyright 2010, 
The North American Menopause Society.

What Happens to Your Body After You Stop Taking the Pill

Design by Betsy FarrellGetty Images

The idea of getting off the pill once you’ve gotten used to a daily alarm schedule and a lighter period can feel like losing a familiar friend. And it might raise more than a few questions about your post-pill lifestyle, like: How will I feel afterwards? Will my skin ever be this clear again? Will I be an emotional monster? Will my periods be as terrible as I remembered?

Turns out, the best predictor of how your body will change after stopping the pill, according to Dr. Lauren Streicher—an Associate Clinical Professor of Obstetrics and Gynecology at Northwestern University’s Feinberg School of Medicine—is how your body acted beforehand. So, if you were experiencing nightmare periods and symptoms like bad cramps, PMS, and headaches prior to starting hormones, she says chances are the same will kick in when you’re off the pill. Oof. Similarly, bad acne and period-related mood swings are likely to come back if you experienced a temporary grace period when you were on the pill. The reason behind this is that your body maintains a stable level of daily hormones—estrogen and progesterone—when you’re on the pill, she says, and starts to cycle again when you stop taking them.

Getty Images

As for how long it takes for your period to return to normal? According to Streicher, it’s highly variable. “Some women will go off the pill, and then they might get their regular spontaneous period a month later or not. Sometimes it’s going to take a few months until things click in.” And unless you’re trying to get pregnant, it’s important to take up other methods of birth control once you stop using the pill. Most women typically start to ovulate again within one to two months after they stop taking the pill, but it’s possible to get pregnant immediately after.

Another important factor to note is that the effects of ditching the pill can differ from someone who’s around the age of 25 or 30 and another woman who’s pre-menopausal. Streicher says that the pill could be masking a host of menopause symptoms like hot flashes, so women should be prepared to deal with big physical changes after stopping the pill.

“And I think there’s still this notion floating around that you should go off the pill periodically to give your body a rest. There’s no science behind that,” says Streicher. Unless you have a personal or medical reason to get off the pill, such as a risk of blood clots or an estrogen-dependent cancer like breast cancer, she says there’s no reason to stop taking the pill if you’re doing well “just because.”

“There’s still this notion floating around that you should go off the pill periodically to give your body a rest. There’s no science behind that.”

In fact, she notes that there are a long list of health benefits to staying on the pill long-term, such as a reduced risk of uterine cancer and ovarian cancer, plus endometriosis and anemia. So until you start considering other options, there are plenty of reasons to keep enjoying life on the pill.

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Memorial Sloan Kettering Cancer Center

This document, provided by Lexicomp ® , contains all the information you need to know about the drug, including the indications, route of administration, side effects and when you should contact your healthcare provider.

Trade names: USA

Arimidex

Trade names: Canada

ACH-Anastrozole; APO-Anastrozole; Arimidex; BIO-Anastrozole; CCP-Anastrozole; JAMP-Anastrozole; Mar-Anastrozole; MED-Anastrozole; MINT-Anastrozole; NAT-Anastrozole; PMS-Anastrozole; RAN-Anastrozole; RIVA-Anastrozole; SANDOZ Anastrozole; TARO-Anastrozole; TEVA-Anastrozole; VAN-Anastrozole [DSC]; Zinda-Anastrozole

What is this drug used for?

  • Used to treat postmenopausal breast cancer.
  • This medicinal product can be used for other indications. Consult your doctor.

What should I tell my doctor BEFORE taking this drug?

  • If you are allergic to anastrozole or any of the other ingredients of this medicine.
  • If you are allergic to this drug, any of its ingredients, other drugs, foods or substances. Tell your doctor about your allergy and how it manifested itself.
  • If you are taking any of the following drugs: estrogen drugs or tamoxifen.
  • If you have not yet entered the menopause period, or you are still able to give birth to a child.
  • If you are breastfeeding. Do not breast-feed while taking this drug or for 2 weeks after your last dose.

This list of drugs and diseases that may be adversely associated with this drug is not exhaustive.

Tell your doctor and pharmacist about all the medicines you take (both prescription and over-the-counter, natural products and vitamins) and your health problems. You need to make sure that this drug is safe for your medical condition and in combination with other drugs you are already taking. Do not start or stop taking any drug or change the dosage without your doctor’s approval.

What do I need to know or do while taking this drug?

  • Tell all healthcare providers that you are taking this drug.These are doctors, nurses, pharmacists and dentists.
  • Perform blood tests as directed by your doctor. Please consult your doctor.
  • This drug lowers estrogen levels in your body, which can thin and weaken bones. This can increase the risk of bone fractures, such as fractures of the spine, hip, and wrist. Consult your doctor.
  • Get a bone density test as directed by your doctor.Consult your doctor.
  • Increases in cholesterol have happened with this drug. If you have any questions, please consult your doctor.
  • This drug may cause fertility problems. This can negatively affect the ability to have children. Consult your doctor.
  • Potential adverse effects of this drug on the fetus. Before you start taking this drug, you will have a pregnancy test to confirm that you are NOT pregnant.
  • If you are at risk of becoming pregnant, you must use birth control during treatment and for some time after your last dose of this drug. Ask your doctor how long to use contraception. If you become pregnant, contact your doctor immediately.

What side effects should I report to my doctor immediately?

WARNING. In rare cases, some people with this drug can have serious and sometimes deadly side effects.Call your healthcare professional or get medical attention right away if you have any of the following signs or symptoms, which may be associated with serious side effects:

  • Signs of an allergic reaction such as rash, hives, itching, reddened and swollen skin with blistering or scaling, possibly associated with fever, wheezing or wheezing, tightness in the chest or throat, difficulty breathing, swallowing or speaking, unusual hoarseness, swelling in the mouth, face, lips, tongue, or throat.
  • Signs of liver problems such as dark urine, feeling tired, lack of appetite, nausea or abdominal pain, light stools, vomiting, yellowing of the skin and eyes.
  • Signs of high blood pressure, such as very severe headache, or dizziness, or loss of consciousness, or blurred vision.
  • Signs of a urinary tract infection, including blood in the urine, burning or painful sensations when urinating, frequent or immediate urge to urinate, fever, pain in the lower abdomen or pelvis.
  • Unusual burning, numbness, or tingling sensations.
  • Swelling of the gland.
  • Bone pain.
  • Shortness of breath.
  • Swelling of the hands or feet.
  • Depression and other mood disorders.
  • Change in vision.
  • Pain in the chest area.
  • Abnormal vaginal bleeding.
  • Vaginal itching or discharge.
  • People with impaired blood vessels in the heart (coronary artery disease) may have more symptoms associated with impaired blood flow to the heart. See your doctor immediately if you experience or worsen chest pain or shortness of breath.

What are some other side effects of this drug?

Any medicine can have side effects. However, many people have little or no side effects. Call your doctor or get medical help if these or any other side effects bother you or do not go away:

  • Tides.
  • Feeling dizzy, tired, or weak.
  • Headache.
  • Nausea or vomiting.
  • Pain or inflammation in the joints.
  • Muscle pain.
  • Sleep disorders.
  • Cough.
  • Sore throat.
  • Back pain.
  • Diarrhea or constipation.
  • Weight gain.
  • Anxiety.
  • Excessive sweating.
  • Flu-like symptoms.
  • Dry mouth.
  • Pelvic pain.

This list of potential side effects is not exhaustive. If you have any questions about side effects, please contact your doctor. Talk to your doctor about side effects.

You can report side effects to the National Health Office.

You can report side effects to the FDA at 1-800-332-1088. You can also report side effects at https: // www.fda.gov/medwatch.

What is the best way to take this drug?

Use this drug as directed by your healthcare practitioner. Read all the information provided to you. Follow all instructions strictly.

  • Take this medication with or without food.
  • Continue taking this drug as directed by your doctor or other healthcare professional, even if you feel well.

What should I do if a dose of a drug is missed?

  • Take the missed dose as soon as you can.
  • If it is time for your next dose, do not take the missed dose and then return to your normal dose schedule.
  • Do not take 2 doses at the same time or an additional dose.

How do I store and / or discard this drug?

  • Store at room temperature in a dry place. Do not store in the bathroom.
  • Store all medicines in a safe place. Keep all medicines out of the reach of children and pets.
  • Dispose of unused or expired drugs. Do not empty into toilet or drain unless directed to do so. If you have any questions about the disposal of your medicinal products, consult your pharmacist. Your area may have drug recycling programs.

General information on medicinal products

  • If your health does not improve or even worsens, see your doctor.
  • You should not give your medicine to anyone and take other people’s medicines.
  • Some medicines may have different patient information sheets. If you have questions about this drug, talk with your doctor, nurse, pharmacist, or other healthcare professional.
  • Some medicines may have different patient information sheets. Check with your pharmacist. If you have questions about this drug, talk with your doctor, nurse, pharmacist, or other healthcare professional.
  • If you think there has been an overdose of a drug, call a Poison Control Center immediately or seek medical attention. Be prepared to tell or show which drug you took, how much and when it happened.

Use of information by consumer and limitation of liability

This information should not be used to make decisions about taking this or any other drug. Only the attending physician has the necessary knowledge and experience to make decisions about which drugs are suitable for a particular patient. This information does not guarantee that the drug is safe, effective, or approved for the treatment of any disease or specific patient.Here are only brief general information about this drug. It does NOT contain all available information on the possible use of the drug with instructions for use, warnings, precautions, information about interactions, side effects and risks that may be associated with this drug. This information should not be construed as a treatment guide and does not replace information provided to you by your healthcare professional. Check with your doctor for complete information on the possible risks and benefits of taking this drug.Use of this information is governed by the Lexicomp End User License Agreement available at https://www.wolterskluwer.com/en/solutions/lexicomp/about/eula.

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© UpToDate, Inc. and its affiliates and / or licensors, 2021. All rights reserved.

90,000 Treatment of unwanted hair growth in women according to the male pattern

Relevance

About 5% – 10% of women have hirsutism – male-pattern hair (hair grows in places that are usually found only in men: mustache, beard area, on the chest, abdomen, back, etc.).etc.). The most common cause of this is polycystic ovary syndrome. Hirsutism can lead to psychological distress, low self-esteem, low self-esteem, depression, shame, and social difficulties.

Review Question

What treatments (excluding laser and light therapy separately) work best for hirsutism?

Study Profile
We included 157 studies published up to June 2014, in which 10,550 people were studied. The participants were women with an average age of 25 years. There were significant differences in the quality of the way the studies were conducted; more than half did not have blinding, and this may have influenced the presentation of outcomes. Most of the studies were conducted at selected centers in Europe and lasted from six to 12 months. A variety of treatment procedures have been evaluated, mostly in isolated studies. These included some topical treatments, lifestyle modifications, oral contraceptives (OCs), drugs to suppress the effects of hormones that are responsible for male traits, and combination therapy.Participant-rated improvement and the impact on quality of life were examined in a minority of studies, while most studies measured physician-assessed reductions in hirsutism as well as blood androgen levels. Half of the studies reported adverse events and about one third reported other signs and symptoms, such as oily skin and menstrual irregularities, which may be related to increased blood androgen levels.

Key Findings

Oral contraceptive (OC) (birth control) pills reduced hair count, but this reduction was not consistent across studies, although two OCs (ethinyl estradiol 35 mcg + cyproterone acetate 2 mg versus ethinyl estradiol 30 mcg + desogestrel 0.15 mg) proved to be effective to the extent that it can be considered important for women with hirsutism.

Of the antiandrogens (drugs with anti-androgenic effects), flutamide has been evaluated by both women and doctors as more effective than placebo. Spironolactone was also effective, but data were only available for physician evaluations. Finasteride has not shown conclusive efficacy based on assessments by both women and researchers. The addition of cyproterone acetate (antiandrogen) to OC was found to increase the beneficial effect of OC in reducing hair growth.

Insulin sensitizers (antidiabetic drugs) and lifestyle changes had no apparent benefit in terms of the severity of hirsutism.Unfortunately, women’s self-assessment, as well as the effect of hirsutism on their quality of life, were outcomes that were not adequately addressed in studies.

Well-known adverse events reported for various drugs, such as stomach and intestinal pain, breast tenderness, decreased libido and dry skin with flutamide and finasteride; irregular bleeding – when using spironolactone; nausea, diarrhea and bloating – when using metformin; and hot flashes, decreased libido, vaginal dryness, breast tenderness and headaches – when using analogs of gonadotropin-releasing hormones (GnRH).

There were no significant differences in blood androgen levels between the different treatment groups; OCs had a positive effect on acne (blackheads), and insulin sensitizers improved menstrual regularity.

We expected to find evidence that combining OC with an antiandrogen would be more effective than, for example, OC alone, but the lack of research did not allow us to draw such conclusions.

Overall, we concluded that OC (especially with antiandrogenic activity), OC in combination with cyproterone acetate, flutamide and spironolactone are effective in the treatment of hirsutism.However, as a rule, additional cosmetic measures are required (epilation, waxing, bleaching, electrolysis, laser and photo epilation), because it takes at least six to 12 months to achieve the optimal effect. In addition, because of the distress associated with hirsutism and its impact on quality of life, psychological support should be part of treatment.

Quality of evidence

Overall, the quality of the evidence for the various outcomes was rated moderate to very low on average.The important reasons for this were that the studies did not have blinding, or had a small sample size.

The baby does not have enough breast milk

The most common reasons for the lack of milk are inadequately rare attachments to the breast, supplementary feeding with formula, violation of technique (incorrect attachment), and most mothers understand this. But there are other, “hidden” reasons that need to be borne in mind.

  • Taking certain medications. Drugs that can reduce milk production include antihistamines and some vasoconstrictors, some weight loss and appetite suppressants, high doses of vitamin B6, diuretics, etc.e. There are other drugs, including those dispensed without a prescription, which may not directly harm the baby, but may affect the amount of milk. Therefore, it is always a good idea to contact a qualified lactation counselor before taking any medication. You can also learn on your own about the effect of the drug on lactation in the book by Dr. Thomas Hale. Remember that the leaflets in the medicine box are not the best source of information, and that not all doctors are knowledgeable enough about how medicines affect breastfeeding.Always doubt if your doctor advises weaning your baby for the duration of treatment, because there are many alternative medicines and treatments that are not contraindicated for breastfeeding.

  • Taking hormonal contraceptives. It is a well-established fact that contraceptives containing synthetic estrogen can – and sometimes do quite quickly – lead to a decrease in milk production. And although most women use drugs containing progesterone alone, this should also be treated with caution.You should not take any hormonal contraceptive medication earlier than 6 to 8 weeks after childbirth. This time will be quite enough for the body to adapt to produce a sufficient amount of milk and become less susceptible to the influence of foreign hormones. Also, up to 6 – 8 weeks, the child’s liver is not yet mature enough to break down the hormones of the contraceptive well. After this time, if a woman wants to take hormonal contraceptives, it is better to start with progesterone-containing mini-pills.This drug can be quickly canceled if the milk becomes noticeably less. Most lactation specialists do not recommend Depo-Provera injections because it lasts three months and cannot be reversed at will. Estrogen-containing contraceptives should be avoided until at least 6 months of age and until the baby is good at digesting solid foods.
  • Decreased thyroid function (hypothyroidism). In some women, this condition first occurs during pregnancy and lactation.It is always a good idea to get tested for thyroid hormones if the usual methods to increase milk production do not help. Symptoms of hypothyroidism also include hair loss, dry skin, chilliness, poor appetite, extreme fatigue, depression, and swelling along the front of the neck. If, in fact, hypothyroidism is detected, a medicine to enhance the function of the thyroid gland is compatible with breastfeeding.
  • Anemia. As in the case of impaired thyroid function, if conventional techniques to increase milk production do not help and no other cause is found, anemia should be ruled out.Mothers with anemia also have an increased risk of blocked milk ducts and inflammation of the mammary glands.
  • Smoking. Mothers who smoke more than 20 cigarettes a day usually have less milk. Their children also tend to gain weight more slowly than those whose mothers smoke less or no smoke at all.
  • Rapid weight loss. During breastfeeding, it is not recommended to lose more than 450 g per week or 1800 g per month. If you lose weight more intensively, milk may become less, in addition, this poses some risk to the baby.Have a reasonable physical activity and consume at least 1,800 calories a day while you are breastfeeding. Avoid slimming drinks and other fashions.
  • Preceding hormonal disorders. Those who have had problems conceiving or carrying a child may have problems with the amount of milk. Although – for many mothers with disabilities of this kind, this is not the case. With polycystic ovary syndrome, not enough milk may be produced.
  • Previous breast surgery or breast injury. Women who have undergone breast augmentation or resection surgery are at risk of never receiving full lactation. This is more likely in situations. When the ducts were crossed and did not recover, or their patency was not restored. Operations in which the nipple has been removed and then transferred to another place is fraught with the most severe damage to the ducts and nerves. Before doing such operations, carefully discuss with your doctor the question of maintaining the possibility of breastfeeding in the future.If the doctor says that the operation will not affect breastfeeding in any way, ask someone else for advice. Because this is almost always not true! Indeed, many women feed their children after such operations, albeit not quite fully. However, if a woman really wants to breastfeed her future children, she should not easily decide on such operations. Women who have undergone breast trauma (burns, bruises, radiation therapy, birth defects, etc.) are also more prone to milk supply problems for many of the reasons listed above.Most of them can feed a baby, albeit not fully.

  • Difficulty separating the placenta. If the placenta has not separated on its own and is completely bloody after delivery for more than 6 weeks, this is a possible reason for insufficient milk production. Heavy postpartum hemorrhage can also cause low milk supply.
  • Breast underdevelopment. It is very rare that the mammary glands simply cannot produce enough milk for the baby.Simply put, the milk ducts and glandular tissue are not sufficiently developed to function properly. Such women note that their breasts did not change their shape or size during pregnancy. Also, one gland can differ significantly in size and shape from another. Moms do not feel “milk coming” in the early postpartum period and never feel full or hardened. Nevertheless, these women should be supported in their efforts to feed. Let them need supplementary feeding with a mixture so that the baby’s nutrition is sufficient – yet the milk that the baby will receive from the mother’s breast is priceless.
  • Nipple abuse. All babies have a need to suck, and it is this that often ensures that the baby will be at the breast often enough to produce the right amount of milk. Avoid giving your baby a pacifier as much as possible. In addition to the fact that nipple sucking affects milk production, it has been shown to increase the risk of otitis media, thrush, and premature breast abandonment. If you still use a pacifier, give it after feeding or if you see that the baby really loves to suckle it.Avoiding the use of a nipple is an effective way to increase milk supply when needed.
  • Early complementary foods. If the baby is given anything other than breast milk before 6 months, this can lead to the mother having less milk. There are other negative points as well. Solid food displaces mother’s milk from the baby’s diet. As a result, he suckles less often, and accordingly less stimulates the mammary glands. Avoid introducing complementary foods (including cereals) before 6 months and breastfeeding BEFORE offering solid foods.Do this until your baby is one year old. Thus, he will suck often and most of the calories will come from your milk, as it should be in the first year of life. Continue feeding your baby on demand and after the introduction of solid food. Give water and juices only with meals and from a cup. The total juice should not exceed 90 – 120 grams.
  • When a child is taught to sleep all night. Oftentimes, they try to “train” children to sleep all night too early. This often causes the mother to have less milk.If the child himself sleeps all night by his own will, and you have enough milk, then let him sleep. But resist the temptation to train him to sleep, especially if you are in doubt whether you have enough milk. Night feeds have the most beneficial effect on the amount of milk.
  • Incorrect attachment or violation of the act of sucking in a child. Both of these problems have a negative effect on milk supply because the breast does not empty properly. The body regards this inadequate drainage over time as a signal for a decrease in milk production.If you suspect your baby has such a problem, call a qualified lactation specialist. It should be noted that you need to check the child’s health with a good doctor.
  • When a baby is limited in breastfeeding time or is not offered both breasts at every feed. Have the baby suckle one breast completely and wait until he falls asleep and releases it himself, or until he stops and continues to suck and swallow. Always offer him both breasts at every feed.The baby may not always want to suckle on the other breast, but always needs to be offered. Always start feeding with the breast that the baby sucked last (or sucked more briefly in the last feed), or that did not suck at all. Feeding in this way will give both breasts the same stimulation.
  • The use of overlays. The pad reduces stimulation of the nipple and the amount of milk sucked at once. Both of these reasons can adversely affect milk production. If pads are needed, select silicone pads, which provide better nipple stimulation, and use them under the guidance of an experienced lactation consultant.
  • The baby confuses a nipple with a bottle nipple. The bottle requires a different type of suckling than the breast, and it is easier for the baby to suck from the bottle. As a result, this can lead to problems – either because the baby does not pick up the nipple correctly, or because the baby prefers a faster and lighter spray from the bottle.

  • Pregnancy. Most mothers have less milk by half of their pregnancy. This happens due to changes in hormonal levels.
  • Return to work, especially before 6 to 8 weeks after delivery. Try to delay the return time to work as much as possible so that the body has time to establish adequate milk production. If you get to work, arrange regular pumping with good suction during the feeding hours. Irregular pumping and poor breast pumping can cause milk supply to diminish quickly. When you are at home with your baby, make it a rule to breastfeed only.No bottles in the evenings and weekends. Even giving the breast to calm the baby (instead of a nipple) can easily help you preserve milk.
  • Scheduled feeding. This interferes with the establishment of the amount of milk that is required and can lead to its decrease, and mainly not immediately, but after a few months. Feed your baby as soon as he gets hungry.
  • Sleepy child. Some babies sleep very long in the first few weeks after birth, rarely ask for food, and suckle for a short time.Until your baby wakes up regularly and begs for food on its own, feed him at least every 2 hours during the day and every 4 hours at night to ensure sufficient milk supply is established.

Finally, studies have shown that excessive consumption of coffee and alcohol also reduces milk flow. Slow milk flow or lack thereof is not directly related to the amount of milk, but may affect it indirectly. Try to “cut” coffee to 4-5 cups a day, and alcohol to an average of one drink a day or less.Strong emotions and fatigue also prevent a full reflex milk flow.

Becky Flora
Source: Breastfeeding Essentials
Translated by Veronica Maslova
In our Center you can consult with a breastfeeding specialist.

90,000 How birth control pills affect menopause symptoms – Medaboutme.ru

Many women take birth control pills, and not only to prevent unwanted pregnancies, but also to treat some gynecological problems.In women aged 45-50 years and older, regular use of oral contraceptives masks the symptoms of menopause, and hot flashes and other signs can be attributed to natural changes in the hormonal background. Is such a disguise dangerous, how does taking pills affect the development of menopause and can the consequences associated with its onset be prevented?

Effect on symptoms

Climax is a natural period in the life of every woman. The body is no longer able to produce enough hormones responsible for regulating the menstrual cycle to support pregnancy.These include estrogens and progesterone.

Women can be recommended several types of oral contraceptives: containing one, as well as two hormones, the latter are called combined. Taking the pills will prevent the body from recognizing the hormone deficiency, therefore, the symptoms go unnoticed in a timely manner.

One of the most common symptoms of an approaching menopause will be an irregular menstrual cycle, and this cannot be seen when taking oral contraceptives.But some studies show that women who take mini-pills with a synthetic form of progesterone may be more likely to experience symptoms of menopause: irregularities in the regulation of the menstrual cycle, hot flashes, etc.

Can taking pills relieve symptoms?

The hormones contained in the combination pills regulate the menstrual cycle, which prevents the development of unpleasant symptoms. But it is worth remembering that many pills can be associated with a number of side effects, which include:

  • mood swings;
  • decreased libido;
  • changes in appetite;
  • excess weight gain;
  • exacerbation of chronic diseases and worsening of the condition.

It is known that these symptoms are similar to those of menopause. Some women may also have an irregular menstrual cycle, bleeding between periods, even while taking pills.

How not to miss the climax?

Sometimes it is difficult to say what will be the symptoms of menopause, and what will be the manifestation of side effects from taking birth control pills. It is quite easy to find out the real reason: you should stop taking pills for a while, this helps to resume the natural cycle.

Doctors note that sometimes it takes time for the natural hormonal background to return to normal and nothing interferes with the regulation of the menstrual cycle.

If the symptoms do not stop, while taking the contraceptive pill is completed, then most likely this indicates the onset of menopause. If the symptoms disappear, then we can safely talk about side effects. In assessing the results, the main thing is the time, several months, which will make it possible to draw the correct conclusion and, of course, an examination by a doctor.

Climax, tablets, pregnancy

If a woman is taking birth control pills, there is no reliable way to say for sure and recognize the symptoms of menopause: the cycle remains regular, because it is controlled by the hormones taken, although there may be exceptions.

If the condition is confirmed by refusal to take pills, this does not mean that pregnancy is impossible. Women need to take care of additional contraception, only a doctor can recommend methods and methods, based on the individual characteristics of the patient, her state of health, sexual activity and a number of other factors.

What to expect from menopause?

Menopause is preceded by a number of symptoms, the main thing is to notice them in a timely manner and seek help from specialists. The first signs of menopause can be considered:

  • increased fatigue;
  • night sweats, moreover, profuse;
  • 90,017 sleep disorders and insomnia;

  • hot flashes;
  • increased anxiety;
  • depressive conditions;
  • decreased libido, discomfort during intimacy;
  • dryness of the mucous membranes;
  • changes in skin, hair.

Menopause is associated with an increased risk of certain pathologies, for example, heart disease, osteoporosis, some of which can be very serious. Therefore, during this period, it is extremely important to regularly visit a doctor and monitor your condition.

How to get rid of unpleasant symptoms?

The climax is individual, like every woman: in some, the symptoms are pronounced and affect the quality of life, in others, they pass more or less easily and imperceptibly. You can get rid of unpleasant symptoms and prevent unwanted consequences through hormone replacement therapy (HRT).

HRT can reduce or prevent symptoms associated with decreased hormone production. But this treatment does not provide contraception, it only relieves symptoms and prevents unwanted consequences. Therefore, women are advised to take care of additional contraceptive measures, which the doctor will help to choose.

Making adjustments to the lifestyle will also help alleviate the condition:

  • Reducing the number of drinks containing caffeine;
  • room temperature regulation for greater comfort;
  • herbal medicine;
  • use of clothing made from natural, breathable fabrics;
  • Use of vaginal lubricants for comfortable sensations;
  • maintaining an active lifestyle;
  • stress prevention;
  • refusal or at least limitation of the amount of alcohol.

Forecast

Climax is a natural period, a process that begins at a certain point in the life of every woman. However, taking birth control pills can mask some of the symptoms of menopause, making it difficult to detect.

Many doctors recommend that their patients take birth control pills to reduce the severity of unpleasant symptoms, but only if there are no contraindications:

  • hormone-dependent tumors;
  • high blood pressure;
  • diseases of the heart and blood vessels;
  • diabetes mellitus;
  • thrombosis.

All women who suggest the onset of menopause should visit a gynecologist. After the examination and some types of research, a plan of therapeutic and prophylactic measures will be proposed, which will not only relieve unpleasant symptoms, but also prevent the development of consequences associated with a reduced production of hormones.

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Functional principle

Passionate temperament or addiction, which can only be dealt with by contacting a specialist? Where is the line after which the sexual appetite becomes irrepressible and harms both the person himself and his partner? The famous Kegel exercises are ideal for training intimate muscles.They can be performed at any time of the day and anywhere – even on the way to work. Contract the vaginal opening muscles for a few minutes every day – and in a few days you will feel the result.

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Composition

Contraceptive pills have gained immense popularity among women. They not only reliably protect against unwanted pregnancy, but are also used for certain diseases.Because of the contraceptive pills, the logest libido was gone. family problems are serious. advise pills that would not reduce so much – in general, right now, I do not want anything. but you can’t live like that! If the reader is interested in which contraceptives do not reduce libido, then you should turn your own. Positive and negative properties of contraceptives. Despite the fact that COC and libido are closely related, most women still prefer this method of contraception. Thus, birth control pills and libido are interrelated, and this is important to consider when choosing a contraceptive.Finding the right pills that do not lower libido can only be done by trial and error. Of course, you do not need to test them without a doctor’s appointment. About a decrease in libido due to contraceptives – this is a common opinion, but not indisputable. There is an opposite opinion that there is allegedly no such effect likar.info/ginekologiya/news-78885-protivozachatochnye-tabletki-ne-snizhayut-libido/ As for the mechanism of reduction. Contraception and libido: does hormonal contraception affect sex drive? Are libido and oral contraception incompatible? Do hormone pills really reduce libido: what does science say and where does the speculation start? Oksana Bogdashevskaya all articles of the author.However, birth control pills that increase libido are also lacking today. Modern medicine does not stand still, so the range of hormonal contraceptives is constantly expanding. Due to the early development of the body, unwanted pregnancies are increasingly common among adolescents. Also, many women are insured against unplanned pregnancy. Finding the right pills that do not lower libido can only be done by trial and error. Of course, you don’t need to test them. Birth control pills and libido are related concepts.Do not take them without your doctor’s permission to avoid negative consequences. If this or that medicine. The reasons for the influence of contraceptive pills on libido are considered. It would seem that hormonal contraceptives are the most convenient and affordable way in modern life to achieve an ideal sex life, eliminating the need to purchase condoms. Today the majority. Birth control pills are at first glance a convenient and affordable way to make your sex life easier and more enjoyable: you no longer need to worry about condoms, there is nothing foreign between you.

Effect from application

Sometimes there is no attraction, but physically nothing interferes with intimacy. Sometimes there is more than enough desire and the body does not show readiness. This situation is quite normal and can change over time. Libido in men, like libido in women, consists of two interrelated parts. The first is mental (desire itself), the second is physical (arousal and body reactions). They do not always act with the same strength or simultaneously. If your partner is such an addictive type, then you have to make a difficult but important decision for yourself: whether you are happy with an open relationship or not.You should not try to reeducate or remake your partner – most likely, this is simply not in your power, and he does not want to stop.

Expert opinion

The problem with these people is that they see sex as the only way to solve their problems. They are, as the name implies, addicted to sex, and you may feel somewhat impersonal. It’s like he’s not having sex with you to make you feel good, but just to relax.If you come across such a lover, look together for a way to more productively relieve tension outside of bed: it can be extreme sports, and meditation, and the practice of mindfulness. It will be good if you still convince your lover to go to a psychotherapist.

Some people often have a strong sexual desire, and, it would seem, there is nothing abnormal in this phenomenon, but experts share a normal sexual desire and increased libido. Increased libido or hypersexuality – increased sexual desire and the resulting sexual activity.Is increased libido good or bad? The answer to this question depends on how hypersexuality affects a person’s life. In some cases, high libido may be an option. Increased libido is associated with an accelerated rate of hormone recovery in the body. This means that after the end of intercourse, after a short time, there is a repeated need for sexual satisfaction. 10 ways to boost your libido Awaken your sensuality. Sex gimmicks. Aphrodisiac foods will help increase libido.It is also good to do inhalations based on these herbs, and some – for example, aloe – can even be consumed in pure form (aloe juice with honey). These herbs are also found in many. Libido is a person’s sexual desire. To increase libido, they often drink vitamins in courses. Ascorbic acid or vitamin. Strengthens the vascular wall, prevents the occurrence of atherosclerosis. Low libido is as serious a problem as sleep deprivation, acne, chronic fatigue, and digestive disorders.These conditions are a warning bell that you are in a danger zone. Characteristic of increased libido in women. Increased libido (nymphomania) is intense sex drive that is very difficult to satisfy due to the rapid recovery of hormone levels after intercourse. Reasons for increased libido: – functional impairment. Girls, what to do? About a week before menstruation, I always noticed that I wanted to. All girls with increased libido – you can cooperate with me). But the libido is so high that the husband is not enough.Cheated on him for the first time in her life. And the husband changed immediately.

Function

The essence of addiction is that a person suffering from it manifests his sexuality in such a way that it harms either himself or his loved ones. Another aspect is secrecy: some sufferers of this disorder lead a secret double life that their regular partner is not even aware of.

How to order?

Fill out the form for consultation and ordering contraceptive pills that do not lower libido.The operator will clarify all the details with you and we will send your order. In 1-10 days you will receive the parcel and pay for it upon receipt.

non-libido-lowering contraceptive pills . means for increasing female libido buy in Amasia. Reviews, instructions for use, composition and properties.

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The famous Kegel exercises are ideal for training intimate muscles.They can be performed at any time of the day and anywhere – even on the way to work. Contract the vaginal opening muscles for a few minutes every day – and in a few days you will feel the result. Libido – Indicates sexual desire or sexual instinct. This term is necessary to describe the various manifestations of sexuality. Libido has two parts: mental (desire) and physical (arousal). Cosmo Online. Relationship. Not news. 18+ Vostock-media. Sensual. For a sensitive lover, the emotional component of sex means much more than technical execution.What lies at the heart of female sex appeal? What is female libido and how can you increase it? What can be done to develop female sexuality? Read about this in our article. Non-verbal sexual signals from women are very diverse, although they are often. How women betray their sexual desire. TSN.ua. A certain body structure, balance of height to weight and a number of other parameters create that very exciting gait for men. And the structure of the body. The propensity for sexual activity determines the presence of libido in a woman, but what is it? Female libido is a natural instinct, the desire to receive pleasure from intercourse, which causes a surge of joyful excitement.Such an emotional state is peculiar only. Female libido is a mysterious thing, and sometimes it can even resemble a roller coaster: today is, and tomorrow is not. However, doctors say that this is a completely natural phenomenon, which has a number of reasons. Most often, temperamental women have high libido. Look for a woman with a strong-willed character, active, cheerful and sociable. Outwardly, this can never be determined either in a woman or in a man. How strong is your libido? With the help of the proposed test, any woman can assess the level of her own libido with a sufficient degree of objectivity.You should only be extremely honest to answer all the questions proposed in this test. Take a pencil and a piece of paper, write down the answers so that. Increased female libido. Natural increase in libido in women occurs in the following situations. The specialists of our center carry out diagnostics, determine the source of the problem and prescribe a correction program. Sometimes there is no attraction, but physically nothing interferes with intimacy. Sometimes there is more than enough desire and the body does not show readiness. This situation is quite normal and can change over time.Libido in men, like libido in women, consists of two interrelated parts. The first is mental (desire itself), the second is physical (arousal and body reactions). They do not always act with the same strength or simultaneously.

Passionate temperament or addiction, which can only be dealt with by contacting a specialist? Where is the line after which the sexual appetite becomes irrepressible and harms both the person himself and his partner?

For a sensitive lover, the emotional component of sex means much more than technical performance.It is important for them to feel a special connection with their partner. People of this type are generous with affection and emotion, but demand the same for themselves.

Try to show him half-naked as often as possible. When you’re at home, you don’t have to wrap yourself up in robes or tracksuits all the time. You’re a woman. Let him go about his business, and at this time, dressed in seductive underwear, as if by chance, walk by. Believe me, this will not go unnoticed.

Women refuse birth control pills. What do they choose instead?

  • Rachel Schraer
  • BBC News

Photo Credit, Getty Images

More women than ever are moving away from pills and condoms in favor of long-term contraception such as implants or spirals. Among them, most of all young women, according to the British health care system NHS.

In 2007, 21% of women in England who received contraception through a dedicated NHS sexual health clinic chose one of the long-acting reversible contraception (LARC). By 2017, this figure had almost doubled to 39%.

Here are some options for long term reverse contraception:

  • copper intrauterine devices (IUDs) or intrauterine devices (IUDs)
  • hormonal intrauterine devices (IUDs)
  • implants
  • injectable contraceptives such as

Hot pills such as oral contraceptives remain by far the most widely used contraceptive method (chosen by 44% of women receiving contraception through British sexual health services), and their use has declined over the past 10 years.

So why are more women looking for alternative forms of contraception?

Since 2010, the UK NHS has been trying to raise awareness of long-term contraceptives and train as many skilled workers as possible.

As women learn about the different options for preventing pregnancy, a large proportion of them are looking for long-acting non-hormonal drugs, says Dr. Anatole Menon-Johansson of Guy and St.Thomas Hospital and Brook, a youth sexual health charity of people.

“The most effective form of advertising for contraception is personal advice. There is a ‘cascade’ effect: when people hear about something from friends and learn from the experience,” he says.

25-year-old Rosa, who now lives in Spain and has set herself a spiral, says: “I was looking for a method of protection on a permanent basis, which I would not have to constantly think about.”

At the same time, 27-year-old Sarah chose a new method of contraception to avoid unnecessary problems: “Pills are problematic.You have to constantly get a new prescription, you forget about them, and they end. ” to photo,

IUDs prevent sperm from entering the uterus, either thanks to copper or hormones

for example, condoms and pills.

Despite the fact that theoretically, with strict adherence to the instructions, the effectiveness of tablets in preventing pregnancy is 99%, with their typical use, this figure, according to the NHS, decreases to 91%.

This only applies to preventing pregnancy – condoms remain the only protection against most sexually transmitted infections.

Pearl Index shows the effectiveness of the chosen method of contraception – the lower this indicator, the more reliable the method of contraception.

  • one in 2,000 women gets pregnant using an implant
  • one in 500
  • uses an IUD – one in 100
  • Approximately one in 10 women gets pregnant while relying on pills

But Sarah mentions another common contraceptive problem … “I was worried about my mental health,” she says.

In recent years, there has also been growing concern about the link between oral contraception and depression.

A 2016 study found that women who regularly take pills were more likely to be diagnosed with depression.

However, researchers have not been able to prove a causal relationship between pill use and depression, although the NHS indicates that mood swings may occur with combined hormonal contraceptive pills, as these drugs contain estrogen and progesterone.

Dr. Menon-Johansson says that he is offering IUD to many women who want to use non-hormonal contraceptives precisely because of mental health concerns, although he notes that there is no clear evidence of such a relationship.

For many women over the age of 20, hormonal contraception has become a part of their life as early as adolescence. And some of them believe that throughout their adult life they have used something that can potentially affect mood – and therefore do not know what life would be without pills.

For example, Gabrielle began to realize that she did not know what her mental state would be like without the hormones that she started taking at age 18.

“I was just wondering what they were doing to me and how I would be without them,” she says.

Now a woman wants to try a diaphragm as a contraceptive, but says that her doctor “has not even heard of it.”

Natika Kheilil, executive director of the Family Planning Association, warns that there is a lot of misinformation around contraception.

Some women are worried that they have been taking hormones for a long time or that their periods have stopped because of the medication. Haleel says, “People shouldn’t be afraid. Contraceptive methods have improved dramatically in the last 20-30 years.”

Photo by Getty Images

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Doctors should discuss different contraceptive options with patients

She believes pills can have a positive effect on women – from skin condition to mood, but long-term contraception is really not for everyone …

For example, 26-year-old Alyssia had a predominantly positive experience with pills, but after 10 years wanted to try a product that contains fewer hormones.However, the hormonal coil did not fit her, and now she wants to remove it.

Misinformation

27-year-old Charlotte suffers from polycystic ovary syndrome and began taking combined oral contraceptives at the age of 15.

According to her, the combined drugs led to an unstable psychoemotional state, and when the woman began to use only progesterone, she had constant bleeding.

“I was told that (hormonal.- Ed. ) a coil would be the perfect solution, but unfortunately I had constant bleeding with it, “she told the BBC.

Dr. Esti Acha, Lead Contraception and Sexual Health Specialist at St. Helens and Knowsley Hospital, notes that the NHS is committed to encouraging doctors to discuss all contraceptive options with their patients, and when they do, many women who come for the pill choose something else.

Now patients ask her about long-term reverse contraception is a big change from what it was 20 years ago when women only asked about pills.

When the birth control pill was introduced almost 60 years ago, it marked a real social revolution. However, the new generation of women is demanding more choices.

And despite varying experiences, almost all of the women we spoke to noted one obvious change – an increase in supply, from pills to other possible alternatives.

Meloflex rompharm solution for in / out introduction 10mg / ml 1.5ml No. 3

City pharmacies:

Vidnoe, Construction street, d.3, pom. 19-25
Mon-Sun 8: 00-20: 00
8 (495) 419-24-84

Domodedovo airport, 2nd floor
Mon-Sun round the clock
8-495-419-12-81

Golikovo, Uskovsky pr-d, 2
Mon-Sun 9: 00-22: 00
+7 495 419-15-65

Zhukovsky, Club street, 4/8
Mon-Sun 9: 00-21: 00
+7 495 221-53-88

Moscow st.Suschevsky Val, 5, p. 5.
Mon-Fri 08: 00-21: 00, Sat-Sun 09: 00-20: 00
8 (495) 419 29 10

Moscow, Avtozavodskaya st., 13/1
Mon-Fri 8: 00-22: 00, Sat-Sun 9: 00-22: 00
+7 (495) 419-24-50

Moscow, Zhivopisnaya st., 12
Mon-Fri 8: 00-22: 00, Sat 8: 00-21: 00, Sun 9: 00-21: 00
+7 495 419-06-22

Moscow, Nizhnyaya Krasnoselskaya street, 35, from 49
Mon-Fri 9: 00-22: 00, Sat-Sun 10: 00-22: 00
+7 495 419 13 48

Moscow, Zamora Machela st., 2A
Mon-Fri 9: 00-22: 00, Sat-Sun 9: 00-21: 00
+7 495 419-12-51

Moscow, st.Bolshaya Tulskaya, 11
Mon-Fri 08: 00-21: 00, Sat-Sun 09: 00-20: 00
8 (495) 419 30 12

Noginsk, 1st Ilyicha st., Building 6/29
Mon-Sun 9: 00-22: 00
+7 495 221-53-85

Noginsk, Dmitry Mikhailov st., 1
Mon-Sun 9: 00-22: 00
+7 495 419-06-21

Odintsovo urban district, Trekhgorka, st.Trekhgornaya, 4
Mon-Sun 09: 00-21: 00
+7 (495) 419-12-85

Khimki, Leninsky prospect, 1k1
Mon-Sun 8: 00-21: 00
+7 495 419 12 97

Composition

1 ml:
– meloxicam 10 mg
Excipients: meglumine – 6.25 mg, glycofurfural – 100 mg, poloxamer 188 – 50 mg, glycine – 5 mg, sodium chloride – 3.5 mg, sodium hydroxide solution 1M – pH 8.6-9, water d / i – up to 1 ml.

Contraindications

combination of bronchial asthma, recurrent polyposis of the nose and paranasal sinuses and intolerance to acetylsalicylic acid and pyrazolone drugs, gastric ulcer and duodenal ulcer (in the acute phase), chronic hepatic failure (CC less than 30 ml / min), active gastrointestinal bleeding, progressive kidney disease, severe liver failure or active liver disease, condition after coronary artery bypass grafting, confirmed hyperkalemia, inflammatory bowel disease, children under 18 years of age, hypersensitivity (in T.old age, coronary artery disease, chronic heart failure, cerebrovascular diseases, dyslipidemia / hyperlipidemia, diabetes mellitus, peripheral arterial disease, smoking, chronic renal failure (CC 30-60 ml / min), gastrointestinal ulcers history, presence of Helicobacter pylori infection, prolonged use of NSAIDs, alcoholism, severe somatic diseases, concomitant use of oral corticosteroids (including prednisolone), anticoagulants (incl.including warfarin), antiplatelet agents (including clopidogrel), selective serotonin reuptake inhibitors (including citalopram, fluoxetine, paroxetine, sertraline).

Application during pregnancy and lactation

Inhibition of prostaglandin synthesis may have an undesirable effect on pregnancy and fetal development. Thus, Meloflex Rompharm is contraindicated during pregnancy.
The drug passes into breast milk, therefore Meloflex Rompharm is contraindicated during lactation.At the time of taking the drug, you must stop breastfeeding.

Side effects

Frequency of side effects: often (more than 1%), infrequently (0.1-1%), rarely (0.01-0.1%), very rarely (less than 0.01%).
From the digestive system: often – dyspepsia, incl. nausea, vomiting, abdominal pain, constipation, flatulence, diarrhea, infrequently – a transient increase in the activity of hepatic transaminases, hyperbilirubinemia, belching, esophagitis, gastroduodenal ulcer, bleeding from the gastrointestinal tract (incl.hidden), stomatitis, rarely – gastrointestinal tract perforation, colitis, hepatitis, gastritis.
On the part of the hematopoietic organs: often – anemia, infrequently – a change in the blood count, incl. leukopenia, thromocytopenia.
On the part of the skin: often – itching, skin rash, infrequently – urticaria, rarely – photosensitivity, bullous eruptions, erythema multiforme, incl. Stevens-Johnson syndrome, toxic epidermal necrolysis.
From the respiratory system: infrequently – the occurrence of attacks of bronchial asthma in persons allergic to acetylsalicylic acid or other NSAIDs.
From the side of the central nervous system: often – dizziness, headache, infrequently – vertigo, tinnitus, drowsiness, rarely – confusion, disorientation, emotional lability.
From the side of the cardiovascular system: often – peripheral edema, infrequently – increased blood pressure, palpitations, flushes of blood to the skin of the face.
From the urinary system: infrequently – hypercreatininemia and / or increased serum urea concentration, rarely – acute renal failure, the relationship with meloxicam intake has not been established – interstitial nephritis, albuminuria, hematuria.
From the senses: rarely – conjunctivitis, visual impairment, incl. blurred visual perception.
Allergic reactions: rarely – angioedema, anaphylactoid / anaphylactic reactions.

Interaction

– Pharmacodynamic interaction:
The simultaneous administration of several NSAIDs (including salicylates) may increase the risk of developing erosive and ulcerative lesions of the gastrointestinal tract due to a synergistic effect, therefore, the use of meloxicam with other NSAIDs is not recommended.
When using meloxicam with diuretics, the patient needs to consume a sufficient amount of fluids, and also requires regular medical monitoring of renal function before and during treatment.
Combined use with indirect anticoagulants increases the risk of bleeding due to inhibition of platelet function and damage to the mucous membrane of the stomach and intestines. Therefore, combined use with NSAIDs and indirect anticoagulants is not recommended.
With the combined use of thrombolytic and antithrombotic drugs with meloxicam, an increased risk of bleeding is possible (periodic monitoring of blood clotting parameters is necessary).
Concomitant use with ACE inhibitors and other antihypertensive drugs in elderly patients with symptoms of dehydration can provoke the development of acute renal failure. In addition, combined use with meloxicam can reduce their hypotensive effect.
Meloxicam increases the nephrotoxic effect of cyclosporine.
Meloxicam may reduce the effectiveness of contraceptives.
– Pharmacokinetic interaction:
NSAIDs can increase the concentration of lithium in the blood serum to a toxic level (decrease in the excretion of lithium by the kidneys).Therefore, the simultaneous use of meloxicam with lithium preparations is not recommended. If necessary, their combined use should carefully monitor the lithium content in the blood serum before, during and after the end of the course of therapy with meloxicam and lithium preparations.
When used simultaneously with methotrexate, the negative effect on the hematopoietic system (the risk of anemia and leukopenia) increases. Periodic monitoring of the hemogram is required.
Kolestyramine accelerates the elimination of meloxicam, increasing the clearance of meloxicam by 50%, decreasing its T1 / 2 by 13 ± 3 hours.This interaction has clinical implications.
When taken simultaneously with antacids, cimetidine and digoxin, no significant clinical interaction was noted.
NSAIDs reduce the effectiveness of contraceptive intrauterine devices.
When meloxicam is used together with drugs that have a known ability to inhibit CYP2C9 and / or CYP3A4 (or are metabolized with the participation of these enzymes), the possibility of a pharmacokinetic interaction should be taken into account.The possibility of interaction of meloxicam with oral hypoglycemic agents cannot be ruled out.
With the simultaneous use of meloxicam with selective serotonin reuptake inhibitors, the risk of gastrointestinal bleeding increases.

Method of administration and doses

The drug is injected deep into the / m. IV is contraindicated.
V / m administration of the drug Meloflex Rompharm is indicated only during the first days of treatment. In the future, treatment is continued with the use of oral forms (tablets).
Osteoarthritis in the acute phase – 7.5 mg / day, if the condition does not improve, you can increase the dose to 15 mg / day.
Rheumatoid arthritis, ankylosing spondylitis – 15 mg / day. Depending on the therapeutic effect, the dose can be reduced to 7.5 mg / day. Do not exceed the daily dose of meloxicam 15 mg.
In elderly patients, the recommended dose for long-term therapy of rheumatoid arthritis or ankylosing spondylitis is 7.5 mg / day. In elderly patients with an increased risk of side effects, therapy should be started with a dose of 7.5 mg / day
In dialysis patients with severe renal impairment, the daily dose of meloxicam 7.5 mg should not be exceeded. In patients with mild or moderate renal impairment (creatinine clearance more than 25 ml / min), there is no need to reduce the dose.
In patients with mild or moderately severe liver dysfunction, there is no need to reduce the dose of Meloflex Rompharm.

Overdose

Increase in dose-dependent side effects.Symptoms: impaired consciousness, nausea, vomiting, epigastric pain, bleeding from the gastrointestinal tract, acute renal failure, acute liver failure, respiratory arrest, asystole. Treatment: symptomatic therapy. Forced diuresis, alkalization of urine, hemodialysis are ineffective due to the high degree of binding of meloxicam to plasma proteins. There is no specific antidote

Special instructions

Care should be taken when treating patients with a history of gastrointestinal diseases.Patients with gastrointestinal symptoms should be monitored regularly. If ulcerative lesions of the gastrointestinal tract or gastrointestinal bleeding occur, Meloflex Rompharm must be canceled.
As with other NSAIDs, potentially life-threatening gastrointestinal bleeding, ulcers and perforations can occur during treatment at any time, whether there is a history of alarming symptoms or a history of serious gastrointestinal complications or absence of these signs.The consequences of these complications are generally more serious in the elderly.
Particular attention should be paid to patients reporting the development of adverse events from the skin and mucous membranes. In such cases, the question of discontinuing the use of Meloflex Rompharm should be considered.
In patients with reduced BCC and decreased glomerular filtration (dehydration, chronic heart failure, liver cirrhosis, nephrotic syndrome, clinically pronounced kidney disease, taking diuretics, dehydration after major surgery), clinically expressed chronic renal failure may appear, which is completely reversible after discontinuation the drug (in such patients, at the beginning of treatment, daily diuresis and renal function should be monitored).
With a persistent and significant increase in transaminases and changes in other indicators of liver function, the drug should be discontinued and control tests should be performed.
In patients at increased risk of side effects, treatment is initiated with a dose of 7.