What are the common side effects of One-A-Day Men’s Health Formula. How can you minimize potential risks while taking this multivitamin. What are the benefits of this supplement for men’s health.

Overview of One-A-Day Men’s Health Formula

One-A-Day Men’s Health Formula is a popular multivitamin supplement designed specifically for men’s nutritional needs. This comprehensive vitamin and mineral blend aims to support overall health, energy levels, and immune function. While generally considered safe when taken as directed, it’s important to be aware of potential side effects.

Common Side Effects of One-A-Day Men’s Health Formula

Most men tolerate this multivitamin well, but some may experience mild side effects, including:

• Upset stomach or nausea
• Diarrhea
• Constipation
• Changes in stool color (often greenish)
• Abdominal discomfort

These effects are typically mild and may subside as your body adjusts to the supplement. Taking the vitamin with food can often help minimize digestive issues.

Are there ways to reduce the likelihood of side effects?

To minimize potential side effects, consider these tips:

1. Take the supplement with a meal
2. Stay well-hydrated throughout the day
3. Start with a lower dose and gradually increase if needed
4. Avoid taking on an empty stomach
5. Consult your healthcare provider if side effects persist

Severe Side Effects and Allergic Reactions

While rare, some individuals may experience more serious adverse reactions to One-A-Day Men’s Health Formula. It’s crucial to be aware of these potential issues and seek immediate medical attention if they occur.

What are the signs of a serious allergic reaction?

Signs of a severe allergic reaction may include:

• Rash or hives
• Itching
• Swelling of the face, lips, tongue, or throat
• Difficulty breathing or swallowing
• Chest tightness
• Unusual hoarseness

If you experience any of these symptoms, stop taking the supplement and seek emergency medical care immediately.

Long-Term Considerations and Precautions

While One-A-Day Men’s Health Formula is generally safe for long-term use, it’s essential to be mindful of potential interactions and cumulative effects over time.

Can One-A-Day Men’s Health Formula interact with medications?

Yes, this multivitamin may interact with certain medications. It’s important to inform your healthcare provider about all supplements and medications you’re taking. Some potential interactions include:

• Antibiotics: Take the multivitamin at least 2-3 hours before or after antibiotic doses, especially tetracyclines and quinolones.
• Blood thinners: The vitamin K content may interfere with anticoagulant medications.
• Thyroid medications: Calcium and iron in the supplement may affect absorption.

Always consult your doctor or pharmacist about potential drug interactions.

Benefits of One-A-Day Men’s Health Formula

Despite potential side effects, this multivitamin offers numerous benefits for men’s health when used appropriately:

• Supports overall nutritional balance
• Promotes heart health with B-vitamins and antioxidants
• Aids in maintaining healthy blood pressure levels
• Supports immune function with vitamins C, D, and zinc
• Promotes muscle health and energy production
• Supports prostate health with lycopene and selenium

How does One-A-Day Men’s Health Formula support prostate health?

The formula contains key nutrients like lycopene, selenium, and zinc, which have been associated with prostate health. These compounds may help reduce the risk of prostate issues and support overall urinary function in men.

Proper Usage and Dosage Guidelines

To maximize benefits and minimize risks, it’s crucial to follow proper usage guidelines for One-A-Day Men’s Health Formula:

• Take one tablet daily with food
• Do not exceed the recommended dosage
• Store in a cool, dry place away from direct sunlight
• Keep out of reach of children

Is it safe to take One-A-Day Men’s Health Formula with other supplements?

While it’s generally safe to take this multivitamin with other supplements, it’s important to be cautious about overlapping nutrients. Excessive intake of certain vitamins and minerals can lead to adverse effects. Always consult with a healthcare professional before combining multiple supplements.

Special Considerations for Specific Health Conditions

Certain health conditions may require special consideration when taking One-A-Day Men’s Health Formula:

Diabetes

The chromium content in this supplement may affect blood sugar levels. Diabetic individuals should monitor their glucose closely and consult their healthcare provider.

Kidney Disease

Those with kidney problems should be cautious about vitamin A and potassium intake. Consult a nephrologist before starting this supplement.

Gastrointestinal Disorders

Men with conditions like ulcerative colitis or Crohn’s disease may need to be cautious due to potential digestive side effects.

Alternatives to One-A-Day Men’s Health Formula

For those who experience persistent side effects or are looking for alternatives, consider these options:

• Food-based multivitamins
• Liquid or powder formulations for easier absorption
• Individual nutrient supplements based on specific deficiencies
• Dietary changes to increase nutrient intake naturally

How do food-based multivitamins differ from synthetic ones?

Food-based multivitamins are derived from whole food sources, which may be easier for the body to absorb and utilize. They often contain additional beneficial compounds found in foods, such as phytonutrients. However, they may be more expensive and have shorter shelf lives compared to synthetic vitamins.

Understanding Nutrient Interactions and Absorption

The effectiveness of One-A-Day Men’s Health Formula depends not only on its ingredients but also on how well your body can absorb and utilize them. Several factors can influence nutrient absorption:

• Timing of intake
• Presence of other nutrients
• Overall diet and gut health
• Age and individual metabolism

How can you enhance nutrient absorption from your multivitamin?

To maximize absorption, consider these strategies:

1. Take fat-soluble vitamins (A, D, E, K) with a meal containing healthy fats
2. Space out calcium and iron intake, as they can compete for absorption
3. Maintain a healthy gut microbiome through a balanced diet and probiotics
4. Pair vitamin C with iron-containing foods to enhance iron absorption
5. Avoid excessive alcohol and caffeine consumption, which can interfere with nutrient absorption

Monitoring and Assessing Supplement Effectiveness

While taking One-A-Day Men’s Health Formula, it’s important to monitor its effectiveness and any potential issues. Regular health check-ups and blood tests can help assess your nutrient levels and overall health status.

How often should you have your nutrient levels checked?

The frequency of nutrient level checks can vary based on individual health status and concerns. Generally, an annual comprehensive blood panel that includes vitamin and mineral levels is recommended. However, those with specific health conditions or on certain medications may need more frequent monitoring.

Key indicators to watch for include:

• Energy levels and overall vitality
• Immune function and frequency of illnesses
• Skin, hair, and nail health
• Digestive function and regularity
• Mental clarity and cognitive performance

Lifestyle Factors and Supplement Efficacy

The effectiveness of One-A-Day Men’s Health Formula can be significantly influenced by various lifestyle factors. Optimizing these aspects of your life can enhance the benefits of the supplement and promote overall health:

Diet and Nutrition

A balanced, nutrient-rich diet is crucial for maximizing the benefits of your multivitamin. Focus on incorporating a variety of fruits, vegetables, whole grains, lean proteins, and healthy fats into your meals.

Physical Activity

Regular exercise not only supports overall health but can also improve nutrient absorption and utilization. Aim for at least 150 minutes of moderate-intensity aerobic activity or 75 minutes of vigorous-intensity activity per week.

Sleep and Stress Management

Adequate sleep and effective stress management are essential for optimal health and can impact how your body processes nutrients. Prioritize 7-9 hours of quality sleep per night and incorporate stress-reduction techniques like meditation or yoga into your routine.

Hydration

Proper hydration is crucial for nutrient transport and overall bodily functions. Aim to drink at least 8 glasses of water per day, adjusting based on activity level and climate.

How does alcohol consumption affect nutrient absorption?

Excessive alcohol intake can interfere with the absorption and metabolism of several nutrients, including:

• B vitamins, particularly thiamine and folate
• Vitamin A
• Vitamin D
• Calcium
• Zinc

Moderate alcohol consumption (up to one drink per day for men) is generally considered safe, but it’s best to avoid alcohol when taking your multivitamin to ensure optimal absorption.

Future Developments and Research in Men’s Health Supplements

The field of nutritional supplements is constantly evolving, with ongoing research into more effective formulations and targeted health benefits. Some areas of focus for future developments in men’s health supplements include:

• Personalized nutrition based on genetic profiles
• Advanced delivery systems for improved nutrient absorption
• Integration of probiotics and prebiotics for gut health
• Incorporation of adaptogens for stress management
• Nanotechnology for enhanced bioavailability

What role might artificial intelligence play in supplement formulation?

Artificial intelligence (AI) is poised to revolutionize the supplement industry by:

1. Analyzing vast datasets to identify optimal nutrient combinations
2. Predicting individual nutrient needs based on lifestyle and health factors
3. Optimizing formulations for specific health outcomes
4. Simulating nutrient interactions and absorption patterns
5. Personalizing supplement recommendations based on real-time health data

As research progresses, we can expect to see more tailored and effective supplement options for men’s health, potentially reducing side effects and maximizing benefits.

Environmental and Ethical Considerations

When choosing a multivitamin like One-A-Day Men’s Health Formula, it’s important to consider the environmental and ethical implications of supplement production and consumption. Here are some factors to keep in mind:

Sustainability

Look for brands that prioritize sustainable sourcing of ingredients and use eco-friendly packaging materials. Some companies are now offering refillable containers or biodegradable packaging to reduce waste.

Ethical Sourcing

Consider supplements that use ethically sourced ingredients, ensuring fair labor practices and responsible harvesting methods, particularly for plant-based components.

Animal Testing

If you’re concerned about animal welfare, research brands that avoid animal testing and use alternative methods to ensure product safety and efficacy.

Natural vs. Synthetic Ingredients

While both natural and synthetic vitamins can be effective, some consumers prefer naturally derived nutrients. Research the pros and cons of each to make an informed decision.

How can consumers make more environmentally conscious choices when it comes to supplements?

To make more eco-friendly supplement choices, consider these tips:

1. Choose brands with minimal packaging or recyclable materials
2. Opt for larger containers to reduce overall packaging waste
3. Look for certifications like USDA Organic, Non-GMO Project Verified, or B Corp
4. Support companies with transparent supply chains and sustainability initiatives
5. Consider whole food supplements or increasing nutrient intake through diet when possible

By considering these factors, consumers can support more sustainable and ethical practices in the supplement industry while still prioritizing their health needs.

One-A-Day Men’s Health Formula Side Effects: Common, Severe, Long Term

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Generic name: multivitamin

Medically reviewed by Drugs.com. Last updated on Jun 21, 2023.

Note: This document contains side effect information about multivitamin. Some dosage forms listed on this page may not apply to the brand name One-A-Day Men’s Health Formula.

Applies to multivitamin: oral capsule, oral liquid, oral tablet, oral tablet disintegrating. Other dosage forms:

• injection injectable, injection solution, oral capsule, oral elixir, oral liquid, oral tablet, sublingual liquid
• oral elixir, oral tablet, oral tablet extended release
• oral capsule, oral tablet
• oral tablet
• oral liquid, oral solution, oral tablet chewable
• oral capsule

Warning

If your product has iron in it:

• Accidental overdose of drugs that have iron in them is a leading cause of deadly poisoning in children younger than 6 years of age. Keep
  away from children. If this drug is taken by accident, call a doctor or poison control center right away.

Serious side effects

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your
doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

All products:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing;
  tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue,
  or throat.

If your product has iron in it:

• Black, tarry, or bloody stools.
• Fever.
• Very upset stomach or throwing up.
• Very bad belly pain.
• Throwing up blood or throw up that looks like coffee grounds.
• Stomach cramps.

Other side effects

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical
help if any of these side effects or any other side effects bother you or do not go away:

All products:

• Upset stomach or throwing up.

If your product has iron in it:

• Constipation.
• Change in color of stool to green.
• Diarrhea.
• Belly pain.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical
advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

Frequently asked questions

• What is Foltanx prescribed for?

More about One-A-Day Men’s Health Formula (multivitamin)

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Patient resources

• Patient Information

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Professional resources

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Related treatment guides

• Dietary Supplementation

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer

One-A-Day Men’S Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Uses

This combination of vitamins and selected minerals is used to prevent or treat vitamin deficiency due to poor eating habits, problems that affect the body’s ability to absorb nutrition from food, or increased need for vitamins and minerals due to stress or illness. Vitamins are needed for the body to function well.This vitamin/mineral combination contains high levels of B vitamins (such as folic acid, niacin, B-1, B-2, B-6, and B-12) and vitamin C. It also contains other vitamins (A, D, and E) and minerals such as zinc. This medication does not contain iron and has only a small amount of calcium. It should not be used to treat “iron-poor” blood (anemia) or to prevent osteoporosis.

How to use One-A-Day Men’s Tablet

Take this medication by mouth with or without food as directed by your doctor, usually once or twice daily. If stomach upset occurs, it may help to take this product with food.

Take this medication 2 to 3 hours before or after taking certain antibiotics (including tetracyclines, quinolones such as ciprofloxacin). The minerals in this product may interfere with the antibiotic, preventing it from being absorbed.

Side Effects

Nausea, stomach upset, diarrhea, flushing and unpleasant taste may occur. If any of these effects last or get worse, notify your doctor or pharmacist promptly.

If your doctor has prescribed this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: mental/mood changes, unusual weakness.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to any of its ingredients such as folic acid; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood count (such as pernicious anemia, megaloblastic anemia, vitamin B-12 deficiency), high calcium levels, kidney disease, liver disease.

This medication is not recommended for use in children under 12 because of increased risk of some vitamins/minerals building up to harmful levels in the body.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This drug passes into breast milk. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Some products that may interact with this drug are: altretamine, cisplatin, levodopa, hydantoins (such as phenytoin), methotrexate, pyrimethamine.

Does One-A-Day Men’s Tablet interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overuse may include: symptoms of liver disease (such as nausea/vomiting that doesn’t stop, dark urine, stomach/abdominal pain, yellowing of eyes/skin), kidney disease (such as back pain, painful urination, change in amount of urine), bone pain, mental/mood changes, severe headache.

Keep all medical and lab appointments.

Remember that it is best to get your vitamins and minerals from healthy foods. Maintain a well-balanced diet and follow any dietary guidelines as directed by your doctor. B vitamins, including folic acid, are naturally found in leafy greens and other vegetables, and citrus fruits. You will also find folic acid in enriched grains such as bread, pasta and cereal.

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from light and moisture. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Today on WebMD

A side effect that has changed the lives of millions of men

One of the main conditions for a harmonious and long relationship between a man and a woman is the physical and sexual health of the partner. However, daily troubles, conflicts at work, stressful situations, the desire to succeed in life sometimes affect both the physical and sexual well-being of the stronger sex. And now, to unpleasant situations at work and daily stresses, problems in the intimate sphere gradually begin to be added, which sometimes fall on the heads of men with a diagnosis of “erectile dysfunction”. In this context, it should be remembered that the problem of erectile dysfunction can be eliminated with the help of modern effective drugs with a favorable safety profile.

The term “erectile dysfunction” was proposed in 1988 by the US National Institutes of Health (National Institutes of Health) and replaced the outdated concept of “impotence”. Erectile dysfunction is defined as the inability to achieve and/or maintain an erection sufficient for sexual intercourse. In the structure of sexual disorders, this pathology occupies a leading place in terms of frequency of occurrence and social significance [1, 2].

A NEW ERA IN THE TREATMENT OF ERECTILE DYSFUNCTION

A revolutionary event in the field of erectile dysfunction treatment was the appearance in 1998 of the drug sildenafil citrate, known under the trade name Viagra ^® [3].

Interesting Facts:

• Viagra® is known worldwide for its side effects. The results of clinical studies of sildenafil conducted in 1992 with the participation of several thousand patients with coronary heart disease disappointed the developers of the drug Viagra P. Dunn and A. Wood, however, its side effect, which was reported by many participants in the study, namely: a pronounced effect on blood flow in the area of ​​the pelvic organs (including the penis), prompted the idea of ​​using this drug for the treatment of erectile dysfunction [4];
• later, sildenafil also showed efficacy in the treatment of pulmonary hypertension [5];
• in 1998. Viagra ^® was mentioned in connection with the award of the Nobel Prize in Physiology and Medicine [6];
• Viagra ^® was awarded the Galen Prize in 1999 in the Netherlands, in 2000 in France and Great Britain, and in 2001 in Canada [7].
• in 2001, Pfizer was awarded the Queens Award for Enterprise (UK) for the discovery and development of Viagra ^® [8];
• in 2003, Viagra ^® won the nomination “The brightest brand of the Ukrainian pharmaceutical market” [9].

Sildenafil is a selective inhibitor of cyclic guanosine monophosphate specific phosphodiesterase type 5 (PDE5), in cavernous bodies, where PDE5 is responsible for the breakdown of cyclic guanosine monophosphate (cGMP). Blockade of this enzyme leads to the accumulation of cGMP, which causes relaxation of smooth myocytes, providing an erection.

Sildenafil is the gold standard in the treatment of erectile dysfunction today. This is primarily due to its high efficiency, as well as to the oral non-invasive form of sildenafil [10].

It should be noted that the effect of the drug, that is, the onset of an erection, begins 14-20 minutes after taking it [11], and the duration of action of Viagra® 100 mg in most men is 12 hours [12]. Viagra® remains effective even 4 years after the start of regular intake, so, more than 94% of patients who participated in the clinical study of the effectiveness of Viagra®, after 4 years of regular use, noted that they were satisfied with the result of treatment and significantly increased the level of sexual activity [13 ]. With Viagra®, men can have sex more often and longer. Viagra® 100 mg increases the duration of erection in men with erectile dysfunction without changing the characteristics of sperm, and has a positive effect on the resumption of erection after ejaculation in the presence of continuous sexual arousal [14]. It should be noted that Viagra ^® has a favorable safety profile. Thus, the incidence of acute cardiovascular diseases in patients with erectile dysfunction who took Viagra ^® does not exceed that in the general population [2].

Viagra ^® — do not forget about physical pleasure!

Representative office of Pfizer has developed an educational website for Ukrainian consumers, which is dedicated to the problem of erectile dysfunction — top-result.com.ua . On the site you can get information on possible problems with erection and ways to solve it.

REFERENCES

1. Pushkar D.Yu., Rasner P.I. Drug treatment of erectile dysfunction: a preliminary comparison of existing methods//Farmateka. – 2004. – 3.4 (82): 31–35. Available at http://medi.ru/doc/260122.htm dated 09/01/2014.

2. Gorilovsky L.M., Lakhno D.A. Erectile dysfunction//Russian medical journal. 2005; 10:653–656. Available at http://rmj.ru/articles_3734.htm from 01.09.2014.

3. FDA Home Drug Databases Orange Book. Available at http://www.accessdata.fda.gov/scripts/cder/ob/docs/obdetail.cfm?Appl_No=020895& TABLE1=OB_Rx on 08/28/2014.

4. Katzenstein L. Viagra: The Remarkable Story of the Discovery and Launch. New York, NY: Medical Information Press. 2001.

5. Avdeev S.N. Pulmonary hypertension in chronic respiratory diseases. Atmosphere. Pulmonology and Allergology. 2010; 2:2–10.

6. Robert F. Furchgott, Louis J. Ignarro, Ferid Murad. The Nobel Prize in Physiology or Medicine 1998. Press release. Available at http://www.nobelprize.org/nobel_prizes/medicine/laureates/1998/press.html dated 07/30/2014.

7. Prix Galien – winners. Available at http://www.prixgalien.com/en/05/02/winners-sorted-by-medical-field.htm on 29/08/2014.

8. T. Harding Royal birthday award for makers of Viagra. Available at http://www.telegraph.co.uk/news/uknews/1316876/Royal-birthday-award-for-makers-of-Viagra.html on 28/08/2014.

9. Brands of the Ukrainian pharmaceutical market. Weekly PHARMACY. Available at http://www.apteka.ua/online/19779 dated 07/31/2014.

10. Mazo E.B., Dmitriev D.G., Gamidov S.I. et al. Pharmacotherapy of erectile dysfunction // Russian Medical Journal. 2001.9:1077–78. Available at http://rmj.ru/articles_1461.htm from 09/01/2014.

11. Padma-Nathan H., Stecher V., Sweeney M., et al. Minamal time to successful intercourse after sildenafil citrate: results of a randomized, double-blind, placebo-controlled trial//Urology. 2003. 62(3): 400–403.

12. Moncada I., Jara J., Subira D., et al. Efficacy of sildenafil citrate at 12 hours after dosing: Reexploring the therapeutic window//Eur Urol. 2004; 46(3): 357–61.

13. McMurray J.G., Feldman R.A., Auerbach S.M., et al., for the Multicenter Study Group. Long-term safety and effectiveness of sildenafil citrate in men with erectile dysfunction. Ther Clean Risk Management. 2007; 3(6): 975–981.

14. A. Aversa, F. Mazzilli, T. Rossi, et al.; Effects of sildenafil (Viagra) administration on seminal parameters and post-ejaculatory refractory time in normal males; Hyman reproduction. 2000; 15(1): 131–134.

Svetlana Shelepko

Information for the professional activities of medical and pharmaceutical workers.

Viagra® (sildenafil), film-coated tablets, 50 mg and 100 mg; 1 or 4 tablets per pack. Brief instructions for the medical use of Viagra®. Indications. Treatment of erectile dysfunction, which is defined as the inability to achieve and maintain a penile erection necessary for successful intercourse. Method of application and dose. The drug is used orally. The recommended dose of Viagra® is 50 mg and is used, if necessary, approximately 1 hour before sexual intercourse. The maximum recommended dose is 100 mg. The maximum recommended frequency of use of the drug is 1 time per day. Contraindications. Hypersensitivity to the active substance or any of the auxiliary components of the drug; simultaneous use with nitric oxide donors (such as amyl nitrite) or nitrates in any form is contraindicated. Sildenafil is contraindicated in men who are not recommended for sexual activity. Side effects. The most commonly reported adverse reactions were headache, flushing, dyspepsia, visual disturbances, nasal congestion, loss of consciousness, and impaired color perception. Application features. Since sexual activity is associated with a certain risk on the part of the heart, before starting any treatment for erectile dysfunction, the doctor should assess the patient’s cardiovascular status. Methods for the treatment of erectile dysfunction, including sildenafil, should be administered with caution to patients with anatomical deformities of the penis (such as angulation, cavernous fibrosis, or Peyronie’s disease), or patients with conditions that cause priapism. Interaction with other drugs. At study in vitro Sildenafil is a weak inhibitor of cytochrome P450 isoforms. In Vivo Studies : Sildenafil has an effect on nitric oxide/cyclic guanisine monophosphate (cGMP) metabolism and has been found to potentiate the hypotensive effects of nitrates, so concomitant use with nitric oxide donors or nitrates in any form is contraindicated. Vacation category. On prescription. Before using the drug, you must read the instructions for medical use and consult a doctor. Information for doctors and pharmacists. It is intended for distribution at seminars, symposiums, conferences on medical topics. Registration certificates No. UA/0313/01/02, No. UA/0313/01/03 dated April 15, 2013. For more information, please contact the Faiser H. Si. Pi. Corporation” in Ukraine: 03680, Kyiv, st. Amosova, 12, business center “Horizon Park”, tel.: (044) 291-60-50. WUKVGR0214010. Printed with support from Pfizer H.C.P. Corporation.

Viagra Pfizer

The doctor spoke about the side effects of dexamethasone

June 17, 2020, 14:42

COVID-19 pandemic

MOSCOW, June 17. /TASS/. The anti-inflammatory drug dexamethasone, which has been shown to be effective in the complications of COVID-19, has side effects such as increased susceptibility to thrombosis and the ability to cause stomach ulcers. Therefore, only specialists should appoint it. Honored Doctor of Russia Mikhail Kagan told TASS about this.

Read also

The steroid dexamethasone has been called an effective remedy against severe forms of COVID-19

Dexamethasone is a steroid drug with anti-inflammatory and immunosuppressive effects. It is used to treat rheumatoid diseases, asthma, allergies, chronic obstructive pulmonary disease and many other diseases. According to the results of the RECOVERY clinical trial, which involved more than 6 thousand patients with coronavirus infection, dexamethasone reduced the mortality of patients with COVID-19 by a thirdwho were on artificial lung ventilation.

After that, the head of the World Health Organization (WHO) called these results a “scientific breakthrough”. However, the study has not yet been independently peer reviewed and has not been published in any scientific journal. The authors promise to do it in the near future.

Why dexamethasone should be taken with caution

“[Side effects] are the same as other drugs in this group – increased tendency to thrombosis, increased blood pressure, increased blood glucose levels, the ability to cause stomach ulcers, and so on. This is a serious drug , for serious situations with serious side effects, so only an experienced doctor will understand what’s what, Kagan said. 0003

The doctor explained that the drug, according to preliminary results of the study, does not affect the virus itself, it only reduces the excessive inflammation that occurs in the body after infection.

As a prophylaxis and in the first week after infection with coronavirus, Kagan did not recommend using this drug, as it suppresses the immune system. “It can only help the virus,” the doctor explained.

In general, as Kagan explained, dexamethasone has been known to mankind since 1960s and has long been registered for the treatment of autoimmune diseases in all countries, including the USSR and Russia. Corticosteroids are the basis of traditional therapy for many autoimmune diseases, such as systemic lupus erythematosus, glomerulonephritis, bronchial asthma, Kawasaki syndrome, autoimmune thrombocytopenic purpura, and others.

The use of corticosteroids for coronavirus infection is logical, the doctor noted, but there were no unambiguous recommendations, since there was no evidence of the effectiveness of this drug against COVID-19 before. In addition, doctors are aware of the risks of using such steroids. At the same time, in the seventh version of the interim guidelines of the Ministry of Health “Prevention, diagnosis and treatment of a new coronavirus infection” dated June 3, there was a recommendation that this drug can be used in severe cases of the disease, Kagan noted.

“It should be noted that in the UK, the dose of dexamethasone used was significantly lower than recommended by our Ministry of Health – 6 mg per day (in domestic recommendations – 20 mg per day. I think that the British managed to find the optimal dose that already provides a positive effect and minimizes side effects,” the doctor concluded.

How the clinical trials were conducted

The RECOVERY study, which began in March 2020, included more than 6,400 patients with coronavirus infection. Of these, 2.1 thousand people were randomly selected, who were given 6 mg of dexamethasone per day for ten days. The rest of the participants received the usual treatment in such cases.