One rip side effects. 7 Dangerous Side Effects of Steroid Use: What You Need to Know
What are the major side effects of steroid use. How do steroids impact your skin, heart health, and hormones. Can steroid use lead to permanent damage. How quickly do side effects appear after starting steroids. Are the effects of steroids reversible after stopping use.
The Hidden Dangers of Steroid Use: Acne and Skin Damage
Steroid use can wreak havoc on your skin in multiple ways. These powerful drugs stimulate oil glands to produce more fat and cholesterol, resulting in greasier skin. Simultaneously, they prompt increased production of bacteria on the skin. This combination creates the perfect environment for clogged pores and acne breakouts.
Dr. Hallie Zwibel, director of the Center for Sports Medicine at New York Institute of Technology College of Osteopathic Medicine, explains: “The increased oil and bacteria production caused by steroids can lead to severe acne. While these effects may subside after discontinuing steroid use, the risk of permanent scarring remains high due to the severity of steroid-induced acne.”
How quickly can steroid-induced acne appear?
Steroid-induced acne can develop rapidly, often within days to weeks of starting steroid use. The severity and extent of acne can vary from person to person, but it tends to be more severe than typical acne vulgaris.
Can steroid-induced skin damage be reversed?
While the increased oil production and bacterial growth will subside after discontinuing steroid use, the potential for lasting damage remains. Severe acne can lead to permanent scarring, affecting both the texture and appearance of the skin long after steroid use has ended.
Cardiovascular Complications: High Blood Pressure and Heart Attack Risk
Steroid use can have significant impacts on cardiovascular health, potentially leading to long-term complications. Two major concerns are increased blood pressure and elevated risk of heart attack.
How do steroids affect blood pressure?
Steroids cause the body to retain sodium and fluids within days of starting use. This retention puts extra stress on blood vessels, leading to increased blood pressure. Research has shown that regular steroid users typically have blood pressure readings 8 to 10 millimeters of mercury (mm Hg) higher than non-users.
Dr. Jotwani warns: “Chronically high blood pressure can cause heart muscles to stiffen, potentially leading to heart disease or heart failure. While blood pressure may normalize within days of stopping steroid use, any damage sustained by the heart muscle could result in a permanent increase in diastolic blood pressure.”
What is the link between steroids and heart attack risk?
Steroids can increase LDL (bad) cholesterol levels while decreasing HDL (good) cholesterol. This imbalance promotes atherosclerosis, a condition where arteries narrow due to plaque buildup. Dr. Zwibel explains that steroids alter the production of hepatic triglyceride lipase, an enzyme in the liver responsible for cholesterol regulation.
A study published in the journal Circulation revealed that male weightlifters who regularly used steroids for more than two years showed irreversible damage to their arteries, significantly increasing their risk of heart attack.
Psychological Effects: Aggression and Mood Changes
Steroid use can have profound effects on mood and behavior, often leading to increased aggression and irritability. These psychological changes can be severe and potentially dangerous.
How do steroids affect mood and behavior?
The flood of testosterone caused by steroid use can hijack the central nervous system and suppress the production of serotonin, a neurotransmitter associated with feelings of well-being. This hormonal imbalance can lead to:
- Increased irritability and short temper
- Episodes of rage or uncharacteristic aggression
- Heightened anxiety and perception of threats
- Potential for violent responses to perceived threats
Research from Dartmouth has shown that steroid users may perceive more people as threatening and respond with violence in an attempt to protect themselves. These mood changes can occur rapidly after beginning steroid use and may persist throughout the duration of use.
Unexpected Physical Changes: Gynecomastia and Hair Loss
Steroid use can lead to surprising and often unwanted physical changes, including the development of breast tissue in men (gynecomastia) and accelerated hair loss.
Can steroids really cause male breast growth?
Yes, steroid use can indeed lead to the development of “man boobs” or gynecomastia. Dr. Zwibel explains: “Certain enzymes in the body can convert testosterone into estradiol, a form of estrogen, which promotes the growth of breast tissue.” This process can occur within months or even weeks of starting steroid use.
Unfortunately, the breast tissue growth caused by steroids is often permanent. Even after discontinuing steroid use, the expanded breast tissue will not revert to its original size.
How do steroids contribute to hair loss?
Steroid-induced hair loss can begin within weeks or months of starting use. Dr. Jotwani states: “High levels of testosterone are the hormonal factor that induce alopecia, or baldness. Since anabolic steroids send testosterone levels through the roof, they usually cause hair loss.”
Interestingly, hair-restoring drugs like Propecia work by blocking testosterone’s effects on hair follicles. Once hair loss occurs due to steroid use, it is typically permanent and will not regrow even after stopping steroid use.
Reproductive Health: Testicular Atrophy and Infertility
Steroid use can have significant impacts on male reproductive health, potentially leading to testicular shrinkage and reduced fertility.
How do steroids affect testicular function and sperm production?
The excessive testosterone introduced by steroid use can suppress the body’s natural production of luteinizing hormone and follicle-stimulating hormone. These hormones are crucial for signaling the testicles to produce sperm. As a result, steroid users may experience:
- Shrinkage of the testicles
- Reduced sperm count
- Decreased sperm motility
- Overall reduced fertility
The National Institute of Drug Abuse estimates that problems with sperm production affect around half of all steroid users.
Is steroid-induced infertility reversible?
While fertility issues caused by steroid use are often reversible, the recovery process can be lengthy. Dr. Jotwani notes: “It can take months or even years for sperm production and testicular function to return to normal after discontinuing steroid use.” The exact recovery time varies depending on factors such as duration of use, dosage, and individual physiology.
Long-Term Health Risks: Liver Damage and Endocrine Disruption
Beyond the immediate and visible side effects, steroid use can lead to serious long-term health complications, particularly affecting the liver and endocrine system.
How do steroids impact liver function?
Anabolic steroids, especially oral formulations, can be hepatotoxic, meaning they can cause damage to liver cells. Prolonged steroid use may lead to:
- Elevated liver enzymes
- Cholestasis (reduced bile flow)
- Peliosis hepatis (blood-filled cysts in the liver)
- Increased risk of liver tumors
The liver plays a crucial role in metabolizing steroids, and the constant strain of processing high doses can lead to long-lasting damage. Regular liver function tests are essential for individuals using steroids to monitor potential harm.
What are the long-term effects on the endocrine system?
Steroid use can significantly disrupt the body’s natural hormone production and regulation. Long-term effects on the endocrine system may include:
- Suppression of natural testosterone production
- Altered thyroid function
- Disrupted cortisol levels
- Imbalances in growth hormone production
These hormonal imbalances can persist long after steroid use has stopped, potentially leading to a range of health issues including metabolic disorders, growth abnormalities, and chronic fatigue.
Legal and Ethical Considerations: The Dark Side of Performance Enhancement
While the health risks of steroid use are significant, it’s also important to consider the legal and ethical implications of using these substances for performance enhancement.
What is the legal status of anabolic steroids?
In many countries, including the United States, anabolic steroids are classified as controlled substances. Their use without a valid medical prescription is illegal. Penalties for possession, distribution, or use of steroids can include:
- Fines
- Imprisonment
- Disqualification from athletic competitions
- Damage to professional reputation
The legal consequences of steroid use can have far-reaching impacts on an individual’s personal and professional life, extending well beyond the realm of sports and fitness.
What are the ethical concerns surrounding steroid use in sports?
The use of performance-enhancing drugs like steroids raises serious ethical questions in competitive sports. Key issues include:
- Fairness and level playing field in competition
- Pressure on athletes to use steroids to remain competitive
- Role model influence on young athletes
- Integrity of sports records and achievements
Many sports organizations have implemented strict anti-doping policies and testing regimens to combat steroid use. However, the ongoing cat-and-mouse game between athletes using performance-enhancing drugs and regulatory bodies continues to challenge the integrity of competitive sports.
7 Side Effects of Steroids
1
Acne.
Getty Images
Steroids wreck your skin in two ways. First, they cause oil glands to produce more fat and cholesterol, which makes your skin greasier. At the same time, they also prompt your skin to ramp up production of bacteria, explains Hallie Zwibel, D.O., director of the Center for Sports Medicine at New York Institute of Technology College of Osteopathic Medicine. And that combo can clog your pores and lead to pimples.
While the oil and bacteria production—and the zits that come with it—will go away after you stop juicing, you could be left with lifelong damage. Acne caused by steroids can be severe, which ups the risk for permanent scarring, Dr. Zwibel says.
2
High blood pressure.
Petry Oeschger/Getty Images
The hormones in steroids cause your body to retain sodium and fluids within a matter of days. That puts extra stress on your blood vessels, which can lead to high blood pressure.
In fact, when researchers measured the BP of regular steroid users, their numbers were, on average, 8 to 10 millimeters of mercury (mm Hg) higher compared to guys who didn’t take steroids. That might not seem like much, but over time it can take a toll.
Chronically high blood pressure can cause your heart muscles to stiffen, Dr. Jotwani says, which can lead to heart disease or heart failure. And while the effects can be reversed within a few days of stopping steroids, if your heart muscle has already sustained damage, that could lead to a permanent increase in your diastolic blood pressure (the bottom number), because your heart has to work harder to pump blood through your body.
3
Heightened heart attack risk.
Getty Images
In addition to raising your blood pressure, steroids can increase your LDL (bad) cholesterol and lower your HDL (good) cholesterol.
Both of those things cause atherosclerosis (when your arteries become more narrow with plaque), which can lead to a heart attack. This happens because steroids alter the production of hepatic triglyceride lipase, an enzyme in the liver that’s responsible for cholesterol regulation, explains Dr. Zwibel.
Experts can’t say for sure how long you’d need to take steroids for your heart attack risk to increase. But findings published in the journal Circulation show that male weight lifters who regularly used steroids for more than two years had irreversible damage to their arteries.
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4
Aggressive behavior.
Courtesy of Giphy
Steroids don’t just make you irritable and short-tempered. They can send you into a full-on rage and make you do things that normally you’d never dream of. They can also make you more anxious: you might perceive more people as threatening, and you could end up responding violently in an effort to protect yourself, Dartmouth researchers have shown.
The flood of testosterone hijacks your central nervous system and suppresses the production of the feel-good neurotransmitter serotonin. As a result, you’re more prone to feeling angry or stressed.
5
Breast growth.
Screengrab via 20th Century Fox/YouTube
You might be skeptical that male hormones could give you man boobs. But they can—within months or even weeks. That’s because certain enzymes in the body can convert testosterone into estradiol (a form of estrogen), which promote the growth of breast tissue, explains Dr. Zwibel.
Worse, the results will be permanent, even if you quit juicing. Once your breast tissue expands, it’ll never go back to its original size, Dr. Zwibel says.
6
Baldness.
Getty Images
You might notice some of your hair thinning within weeks or months after starting steroids. “High levels of testosterone are the hormonal factor that induce alopecia, or baldness,” Dr. Jotwani says. And since anabolic steroids send your testosterone levels through the roof, they usually cause hair loss.
In fact, testosterone is so good at causing hair loss that hair-restoring drugs like Propecia actually work by blocking the hormone, adds Dr. Jotwani. And once your hair is gone, it won’t come back—even after your ‘roid run ends.
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7
Infertility.
Getty Images
All that extra testosterone from the steroids can shrink your testicles and zap your sperm count. Too-high levels of the hormone can suppress the production of luteinizing hormone and follicle-stimulating hormone, which tell the testicles to produce sperm, explains Dr. Jotwani.
Problems with sperm production affect around half of all steroid users, estimates the National Institute of Drug Abuse. It’ll reverse itself eventually once you stop juicing, but it can take months or even years for things down there to get back to normal, Dr. Jotwani says.
Marygrace Taylor
Marygrace Taylor is a health and wellness writer for Prevention, Parade, Women’s Health, Redbook, and others. She’s also the co-author of Prevention’s Eat Clean, Stay Lean: The Diet and Prevention’s Mediterranean Kitchen. Visit her at marygracetaylor.com.
One Rip sides and doseage
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Hi guys taken delivery of my 10ml vile of one rip today to take along side my Winny 10mg x4 a day plus 2x T5s two days on one day off now had differing advice on dose of onerip to stick the guy i had it of when i told him i was gona stick 1ml eod told me no do 1ml every 5 days i can prob take 1ml eod so what do you think anyone done this or the 5 day dose also what if any sides can i expect as the guys i know that have used it have only said some of them got a lil cough any advice would be massively helpfull thanks:confused1:
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Definitely EOD.
Sides differ from person to person.
I loved using 1Rip but after a few weeks the pinning got too much
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Hi mate how offten did you inject ive heard it has to be frequent as it is only short acting so needs to be injected more often where as i have also been told 1ml every 5 days aswell as other people saying 1ml eod also never heard anything negative on sides only a couple of people saying they had a lil cough
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Is that the lixus “one rip”? I used it for 6 weeks with anavar, and got good results but still felt it was underdosed.
a 10ml vial will last you for 20 days @ 1ml, every other day. I do short (6 week) cycles, up to four a year. Two vials works out at 40 days, and I begin PCT on day 43. Rip blends are a good, cheap way of getting compounds without too many injections. I ended up staying the same weight on the scales, but with more muscle, so they are good for bulking too.
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Yep, you’ll have to pin EOD
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Looking at for next cycle. Thinking 6 week cycle. What are the thoughts on running Test Prop after to take it to 10-12 weeks?
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That’s a long time to pin EOD, but it would work, all a third of 1Rip is is T Prop.
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Yeah true, by the end of it I’ll be walking like Danial Day-Lewis in My Left Foot!!!!! :blink:
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EOD always.
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Reaper 2X3 said:
Yeah true, by the end of it I’ll be walking like Danial Day-Lewis in My Left Foot!!!!! :blink:
Click to expand. ..
Why not use Test E as a base, and jab that twice a week max, and use the OneRip when you see fit?
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So start with a Test E base and bring in the 1rip towards the end of a cycle? Run Test E for 6 and then 1 rip final 6?
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or go with Rohm it has test E rather than prop
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BatemanLondon said:
or go with Rohm it has test E rather than prop
Click to expand…
go with which ever is cheaper. Both the same anyways.
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BatemanLondon said:
or go with Rohm it has test E rather than prop
Click to expand…
thats not test e, thats test ace, another very short-acting ester like prop
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Yeah. Those two are the same thing.
If you’re wanting a 12 week course I’d definitely do 6 weeks test e then then 6 weeks OneRip.
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good point , for some reason i thought it had ent in it lol i should read the labels.. a pointless post from me.
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Cheers Dux. Would i get the results from 6 weeks of Test E and then switching to a lower doage of Test P? being that test E is long ester so wouldnt get much payback for 6 weeks? Maybe better running Test E for 10 weeks then 6 weeks of 1rip?
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Reaper 2X3 said:
Cheers Dux. Would i get the results from 6 weeks of Test E and then switching to a lower doage of Test P? being that test E is long ester so wouldnt get much payback for 6 weeks? Maybe better running Test E for 10 weeks then 6 weeks of 1rip?
Click to expand…
why 6 weeks of test-e, why not just start on 1-rip now?
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I have just started my latest course of one rip and i love the stuff, first course was ROHM now this course is pro chem. .. You will get really good results from one rip and defo EOD it only has a 3 day life span on it so if you do every 5 days it will be like trying to load up on it every time as your body will have done two days dry. Side Effects- Your body temp will be through the roof and you will be sweating walking up the stairs as it increases body temp to shed weight, which kick starts metabolism, also the pip is horrific! im talking you will be struggling to sit down. I had to ease myself into a chair every time i sat down, Seemed to clear up after first 3 weeks though. and its just about manageable, alot of people i know had to actually come off it all together for this reason. But apart from that yea you will get great results, personally wouldnt bother with the winny as it drys your joints right out, I would stack it with Anavar, But these days probably winny anyway to be fair.
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I’ve had biochem or prochem cant think and ROHM 1 rip and found the ROHM to be alot better
EOD is ideal
my experience was a jab on monday you were raring to go on the wednesday
as for sides just mad dreams and a bit of the sweats :sleeping:
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Type 3 poliovirus declared eradicated
WHO experts say wild type 3 poliovirus can now be considered eradicated. Only one strain of the pathogen now survives, poliovirus type one, which continues to spread in Pakistan and Afghanistan. After defeating him, it will be possible to say that polio is completely defeated.
Poliovirus is one of the simplest viruses: it consists of an RNA molecule and a protein capsid. It enters the human body with traces of excrement – that is, from dirty hands or unwashed food – and therefore is most common in poor countries with a low level of hygiene. The poliovirus can settle and multiply in different human cells, and often the infection is asymptomatic, but from time to time it gets to the neurons and disrupts the nervous system, which can lead to paralysis or death.
In total, three strains of poliovirus are known, they differ only in the features of the structure of the capsid. A vaccine has long been developed against them, which exists in two forms. The simplest variant of administration is oral, it is simpler and cheaper, so it is more often used in poor countries, the second variant is injections. However, many people are skeptical about vaccines and spread rumors that they themselves can provoke polio – which is indeed possible, but in extremely rare cases.
Therefore, it was only recently that one of the types of poliovirus was completely eradicated. In 2015, the WHO Special Commission for the Certification of Poliovirus Eradication confirmed that the type 2 virus could be considered eradicated. Doctors observed the last case of infection with it in 1999, since then no one has been able to detect it.
In 2012, the last case of type three poliovirus infection was described in Northern Nigeria. For seven years, laboratories around the world have been looking for it, and only now the WHO commission has officially announced its liquidation.
Only one strain survived, wild poliovirus type one, now prevalent in Afghanistan and Pakistan. Two obstacles prevent him from finally defeating him. The first is the distrust of the population in vaccines, and the second is its side effects. After a person receives a weakened version of the virus, it partially leaves the body in the feces and spreads like a normal virus. At the same time, a weakened strain can mutate and turn into a new, even more pathogenic strain – such strains are called circulating vaccine-derived polioviruses.
These circulating viruses are harmless to the vaccinated person, but they can cause outbreaks in an incompletely immunized population. Thus, the polio epidemic from Afghanistan reaches Africa. And despite the fact that the last case of infection with wild poliovirus type one in Africa was registered back in 2016, circulating polioviruses still continue to threaten the continent.
For more information about the methods scientists use to fight infectious diseases, read our material “It Cannot Be Eliminated”.
Polina Loseva
Found a typo? Select the fragment and press Ctrl+Enter.
Radiotherapy methods.
1. Remote
radiation therapy. between source and
irradiated surface has
distance.
Long distance
– distance
between the radiation source and the irradiated
surface (RIP)=50-80cm.
Close distance
– RIP=1.5-25cm
(average 1.5-7.5 cm).
2. Contact
radial
therapy – the source is adjacent to the organ.
Application
method – the source is placed on the surface
irradiated area. Is used for
treatment of tumors located on
depth of 1-2 cm – continuous irradiation.
Intracavitary
method – introduction of radioactive sources
into the organ cavity. Is used for
treatment of tumors of the oropharynx, neck
uterus, rectum, bladder.
Interstitial
therapy – the tumor is stitched with a thread, in
which introduced Co balls in capsules.
3. Radiosurgery
method. Irradiation
performed on the operating table: either
before tumor removal or after
removal.
TYPES OF SOURCES.
Closed:
capsules, balls.
open:
in ampoules – gold, cobalt, strontium.
RADIATION REACTIONS
AND DAMAGE.
They
accompany radiation therapy and undergo
on one’s own.
General
radiation reactions:
Disorders
from the side of the central nervous system – headaches, dizziness,
dystonia, insomnia, drowsiness,
tearfulness.
Hematological
shifts – oppression of hematopoiesis.
Gastroenteric
disorders – vomiting, diarrhea.
Disorders with
side of the vessels and the heart.
Disorders with
sides of the skin.
Local
radiation reactions:
1. Erythema.
2. Dry
radiodermatitis.
3. Wet
radiodermatitis.
4. Atrophy
epidermis.
5. On
mucous membranes – membranous radiepithelitis.
Prevention
radiation reactions – thymus preparations,
vitamins, hematopoietic stimulants;
dermatomodifying ointments.
Damage
may be early (developing during
3 months after radiotherapy) and
late (radio-induced sclerosis
tissues, radiation ulcers, fibrosis, osteoporosis,
radiation cancer, fistulas). To prevent
radiation damage is carried out sanitation
hollow organs.
RADIATION THERAPY
NON-TUMOR DISEASES.
1. Sharp
surgical diseases: mastitis,
hydroadenitis, felon, paronychia,
osteomyelitis, carbuncles.
2. Diseases
nervous system.
3. Generative-dystrophic
diseases: arthritis, osteochondrosis,
bursitis, neuritis.
4. Neurological
diseases: neuritis, neuralgia,
radiculitis, post-amputation pain
syndrome.
Basic
principles of therapy .
Use small doses; 0.1-0.2Gy is a single
dose for acute inflammation. With chronic
inflammation single dose = 0.3-0.5Gy.
1-2 sessions of irradiation. With ulcers and
mastitis as a result of therapy decreases
pain, inflammation is relieved if the process
in the initial stage, then it is completely
stops. With necrosis and suppuration
irradiation accelerates
melting of the infiltrate, its delimitation.
Radiation therapy leads to regeneration
and rapid epithelialization of wounds; she doesn’t
shown in phlegmon.