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Pristiq weight gain side effects. Pristiq Weight Gain: Understanding Side Effects and Management Strategies

What are the common side effects of Pristiq. How can weight gain be managed while taking Pristiq. What should you know about Pristiq’s impact on appetite and metabolism. Why might Pristiq cause weight changes in some individuals. When should you consult your doctor about Pristiq side effects.

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Understanding Pristiq: An Overview of the Antidepressant Medication

Pristiq is a prescription medication used to treat major depressive disorder in adults. Its active ingredient, desvenlafaxine, belongs to a class of drugs known as serotonin-norepinephrine reuptake inhibitors (SNRIs). Pristiq works by increasing the levels of serotonin and norepinephrine in the brain, which are neurotransmitters associated with mood regulation.

Administered as a tablet taken orally, Pristiq is typically prescribed for long-term use. While it can be an effective treatment for depression, like all medications, it may cause various side effects that patients should be aware of.

Common Side Effects of Pristiq: What to Expect

When starting Pristiq, patients may experience a range of mild side effects as their body adjusts to the medication. These commonly reported side effects include:

  • Dizziness
  • Trouble sleeping (insomnia)
  • Increased sweating
  • Loss of appetite
  • Nausea
  • Headache
  • Constipation
  • Dry mouth
  • Anxiety
  • Sexual side effects

It’s important to note that these side effects are usually temporary and may subside as the body acclimates to the medication. However, if any of these symptoms persist or become bothersome, it’s crucial to consult with a healthcare provider.

Pristiq and Weight Gain: Exploring the Connection

While weight gain was not reported as a common side effect in clinical studies of Pristiq, some patients have reported experiencing weight changes after starting the medication. This raises an important question: Can Pristiq cause weight gain?

The relationship between Pristiq and weight gain is complex. While the medication itself may not directly cause weight gain, it can influence factors that contribute to changes in weight, such as appetite and metabolism. Additionally, weight fluctuations can be a symptom of depression itself, making it challenging to determine the exact cause of weight changes in individuals taking Pristiq.

Factors Contributing to Weight Changes on Pristiq

Several factors may contribute to weight changes in individuals taking Pristiq:

  1. Appetite changes: Some patients may experience an increase in appetite while taking Pristiq, potentially leading to weight gain.
  2. Metabolic effects: SNRIs like Pristiq can affect metabolism, which may influence weight in some individuals.
  3. Improved mood: As depression symptoms improve, some patients may experience changes in eating habits or activity levels that could impact weight.
  4. Individual variations: Each person’s body may respond differently to the medication, leading to varied effects on weight.

Managing Weight Gain While Taking Pristiq: Practical Strategies

If you’re concerned about potential weight gain while taking Pristiq, there are several strategies you can employ to maintain a healthy weight:

  • Monitor your diet: Keep track of your food intake and make conscious choices about nutrition.
  • Stay active: Regular exercise can help manage weight and improve overall mood.
  • Stay hydrated: Drinking water can help control appetite and support overall health.
  • Get adequate sleep: Poor sleep can affect weight management, so prioritize good sleep habits.
  • Consult your healthcare provider: Discuss any concerns about weight changes with your doctor, who can provide personalized advice.

Serious Side Effects of Pristiq: When to Seek Medical Attention

While most side effects of Pristiq are mild, some patients may experience more serious adverse reactions. It’s crucial to be aware of these potential serious side effects and seek immediate medical attention if they occur:

  • Increased blood pressure
  • Mania or hypomania (elevated mood states)
  • Serotonin syndrome
  • Increased risk of bleeding
  • Angle-closure glaucoma
  • Seizures
  • Low sodium levels in the blood
  • Suicidal thoughts or actions (particularly in young adults)

Pristiq carries a boxed warning, the most serious warning from the FDA, regarding the increased risk of suicidal thoughts and actions in children, adolescents, and young adults. While Pristiq is not approved for use in individuals under 18, this risk extends to young adults up to age 24.

Discontinuation Syndrome: Understanding Withdrawal Symptoms

Abruptly stopping Pristiq can lead to discontinuation syndrome, a collection of withdrawal symptoms that can range from mild to severe. These symptoms may include:

  • Nausea
  • Dizziness
  • Headache
  • Irritability
  • “Brain zaps” (electrical shock sensations)
  • Anxiety or agitation

In more severe cases, discontinuation syndrome can lead to serious symptoms such as seizures, suicidal thoughts, or severe aggression. To minimize the risk of these symptoms, it’s crucial to work closely with a healthcare provider when considering stopping Pristiq. A gradual tapering of the medication over several months is typically recommended to safely discontinue use.

Dosage Considerations: Impact on Side Effects

The dosage of Pristiq may influence the likelihood and severity of side effects. While studies have shown that the types of side effects are generally consistent across different dosages, higher doses may increase the risk of experiencing certain side effects.

Pristiq is typically prescribed at a starting dose of 50 mg per day, with the option to increase to 100 mg if needed. Some patients may require doses up to 400 mg daily, although doses above 100 mg have not shown increased effectiveness in clinical trials.

Dosage Adjustments and Side Effect Management

If you’re experiencing troublesome side effects on Pristiq, your healthcare provider may consider adjusting your dosage. This could involve:

  • Lowering the dose to reduce side effects while maintaining therapeutic benefit
  • Splitting the daily dose to minimize peak concentrations in the body
  • Timing the dose to align with your daily routine and minimize disruptive side effects

It’s important to never adjust your Pristiq dosage without consulting your healthcare provider, as improper dosing can lead to withdrawal symptoms or reduced effectiveness of the medication.

Long-Term Use of Pristiq: What to Expect

Pristiq is often prescribed for long-term use in the treatment of major depressive disorder. While many side effects may subside over time as the body adjusts to the medication, some effects may persist or develop with prolonged use. Understanding what to expect with long-term Pristiq use can help patients make informed decisions about their treatment.

Potential Long-Term Effects

Some potential long-term effects of Pristiq use may include:

  • Sexual side effects: Changes in libido or sexual function may persist in some individuals.
  • Weight changes: While not a direct side effect, some patients may experience gradual weight changes over time.
  • Blood pressure changes: Regular monitoring of blood pressure is important during long-term use.
  • Bone health: Some studies suggest long-term SNRI use may affect bone density.

Regular check-ups with your healthcare provider can help monitor these potential long-term effects and adjust treatment as necessary.

Lifestyle Considerations While Taking Pristiq

To maximize the benefits of Pristiq while minimizing side effects, consider incorporating the following lifestyle strategies:

  • Maintain a balanced diet rich in fruits, vegetables, whole grains, and lean proteins.
  • Engage in regular physical activity, aiming for at least 150 minutes of moderate exercise per week.
  • Practice stress-reduction techniques such as meditation, yoga, or deep breathing exercises.
  • Prioritize sleep hygiene by maintaining a consistent sleep schedule and creating a relaxing bedtime routine.
  • Limit alcohol consumption, as it can interact with Pristiq and exacerbate side effects.
  • Stay hydrated by drinking plenty of water throughout the day.

These lifestyle modifications can not only help manage potential side effects but also support overall mental health and well-being.

Navigating Pristiq Treatment: Communication with Your Healthcare Provider

Open and honest communication with your healthcare provider is crucial when taking Pristiq. Regular check-ins can help address any concerns or side effects promptly, ensuring the best possible outcomes from your treatment. Consider discussing the following with your doctor:

  • Any new or worsening side effects you experience
  • Changes in your mood, energy levels, or overall well-being
  • Concerns about weight changes or other physical effects
  • Questions about dosage adjustments or long-term treatment plans
  • Any other medications or supplements you’re taking, as they may interact with Pristiq

Remember, your healthcare provider is your partner in managing your depression and ensuring that your treatment with Pristiq is as effective and well-tolerated as possible.

Alternative Treatment Options: When Pristiq Isn’t the Right Fit

While Pristiq can be an effective treatment for many individuals with major depressive disorder, it may not be suitable for everyone. If you’re experiencing significant side effects or not seeing the desired improvement in your symptoms, your healthcare provider may consider alternative treatment options. These could include:

  • Other antidepressant medications (e.g., SSRIs, TCAs, MAOIs)
  • Psychotherapy or counseling
  • Combination therapy (medication plus psychotherapy)
  • Alternative treatments such as transcranial magnetic stimulation (TMS) or electroconvulsive therapy (ECT) for treatment-resistant depression

The decision to switch treatments should always be made in consultation with your healthcare provider, who can help weigh the potential benefits and risks of different options based on your individual needs and medical history.

Conclusion: Balancing the Benefits and Risks of Pristiq Treatment

Pristiq can be an effective medication for managing major depressive disorder, but like all treatments, it comes with potential side effects that need to be carefully considered. While weight gain is not a commonly reported side effect in clinical trials, some individuals may experience changes in weight or appetite while taking Pristiq.

By staying informed about potential side effects, maintaining open communication with your healthcare provider, and adopting healthy lifestyle habits, you can work towards achieving the best possible outcomes from your Pristiq treatment. Remember that managing depression is a journey, and finding the right treatment approach may take time and patience.

If you have concerns about Pristiq or its side effects, don’t hesitate to discuss them with your healthcare provider. They can provide personalized advice and guidance to help you navigate your treatment journey effectively.

What They Are and How to Manage Them

If you have depression, your doctor might suggest Pristiq as a treatment option for you.

Pristiq is a prescription drug that’s used to treat major depressive disorder in adults.

The active ingredient in Pristiq is desvenlafaxine. An active ingredient is what makes a drug work. Pristiq comes as a tablet that you swallow. It’s usually taken long term.

For more information about Pristiq, including details about its uses, see this in-depth article.

Like other drugs, Pristiq can cause mild to serious side effects. Keep reading to learn more.

Some people may experience mild to serious side effects during Pristiq treatment. Examples of Pristiq’s commonly reported side effects include:

  • dizziness
  • trouble sleeping
  • increased sweating
  • loss of appetite
  • nausea*

* To learn more about this side effect, see the “Side effects explained” section below.

Read on to learn about other potential mild and serious side effects of Pristiq.

Pristiq may cause mild side effects. Examples of mild side effects that have been reported with Pristiq include:

  • dizziness
  • vomiting
  • trouble sleeping
  • increased sweating
  • drowsiness
  • loss of appetite
  • anxiety
  • dry mouth
  • sexual side effects*
  • nausea*
  • headache*
  • constipation*
  • mild allergic reaction*

* To learn more about this side effect, see the “Side effects explained” section below.

In most cases, these side effects should be temporary. And some may be easily managed, too. But if you have any symptoms that are ongoing or bother you, talk with your doctor or pharmacist. And do not stop taking Pristiq unless your doctor recommends it.

Pristiq may cause mild side effects other than the ones listed above. See the Pristiq prescribing information for details.

Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. If you’d like to notify the FDA about a side effect you’ve had with Pristiq, visit MedWatch.

Pristiq can cause serious side effects, though these are usually rare. Serious side effects that have been reported with Pristiq are listed below. Some of these side effects were reported in studies of Pristiq. But others were reported after the drug became available on the market.

  • increased blood pressure
  • mania and hypomania, which cause elevated mood
  • serotonin syndrome, resulting from a buildup of the chemical serotonin
  • increased risk of bleeding, which may be life threatening
  • angle-closure glaucoma, a serious eye condition
  • discontinuation syndrome, which causes withdrawal symptoms
  • seizures
  • low level of sodium in the blood
  • risk of suicidal thoughts and actions*
  • severe allergic reaction†‡

* Pristiq has a boxed warning for this side effect. This is the most serious warning from the Food and Drug Administration (FDA). To learn more, see the “Side effects explained” section below.
† To learn more about this side effect, see the “Side effects explained” section below.
‡ An allergic reaction is possible after taking Pristiq. But this side effect wasn’t reported in studies.

If you develop serious side effects while taking Pristiq, call your doctor right away. If the side effects seem life threatening or you think you’re having a medical emergency, immediately call 911 or your local emergency number.

Get answers to some frequently asked questions about Pristiq’s side effects.

Does Pristiq cause weight gain?

It’s possible. In studies of Pristiq, weight gain was not a reported side effect. But after Pristiq was made available on the market, some people who took it reported gaining weight.

It’s important to note that weight changes, including weight gain, can be a symptom of depression.

If you experience weight gain while taking Pristiq, talk with your doctor. They may have tips to help with this side effect.

If I suddenly stop taking Pristiq, will I have withdrawal symptoms?

Yes, it’s possible. Withdrawal symptoms may be a side effect of stopping Pristiq, and they can be mild or serious. Some of the mild symptoms of withdrawal include:

  • nausea
  • sweating
  • dizziness
  • headache
  • trouble sleeping
  • “brain zaps” (feeling an electrical jolt in the head that may travel to other parts of the body)
  • irritability, anxiety, or agitation

Some serious symptoms of withdrawal include:

  • seizure
  • suicidal thoughts
  • severe aggression
  • increased blood pressure
  • blurry vision

These side effects are more likely to happen if you stop taking Pristiq suddenly. If you want to stop taking Pristiq, talk with your doctor first. They’ll likely recommend that you take a smaller dose for a while rather than stopping Pristiq abruptly. It may take several months to stop taking Pristiq completely.

Will my risk of side effects be higher with the 100-mg dose of Pristiq than with lower doses of the drug?

It’s possible. During studies of Pristiq, people took different doses of the drug. The side effects that were reported were the same for each dosage. But more people who took the 100-milligram (mg) dose reported certain side effects than those who took the 50-mg dose. Some of these side effects were:

  • dry mouth
  • sleepiness
  • trouble sleeping
  • certain sexual side effects*
  • nausea*

* To learn more about this side effect, see the “Side effects explained” section below.

Learn more about some of the side effects Pristiq may cause.

Risk of suicidal thoughts and actions

Pristiq carries a boxed warning about the risk of suicidal thoughts and actions in children, adolescents, and adults ages 24 years and younger. A boxed warning is the most serious warning from the Food and Drug Administration (FDA).

Antidepressants such as Pristiq may increase the risk of suicidal thoughts and actions in people under 25 years of age. The FDA has not approved the use of Pristiq in people ages 18 years or younger.

Symptoms of suicidal thoughts and actions include:

  • sudden changes in mood, behaviors, thoughts, or feelings
  • trouble sleeping
  • new or worsened irritability or depression
  • extreme anger, violence, or aggression
  • extreme increase in talking, excitement, and activity, which can result from mania
  • panic attack
  • impulsive behavior
  • thoughts about dying or hurting yourself
  • suicide attempts
What might help

Keep track of how you feel while taking Pristiq. If you experience any of the symptoms listed above while taking Pristiq, tell your doctor right away.

Consider letting people close to you know about this Pristiq side effect and its symptoms. They can also help you watch out for these symptoms.

If you’re 18 to 24 years of age, your doctor may monitor you more closely for symptoms of suicidal thoughts and actions during Pristiq treatment.

Suicide prevention

If you know someone at immediate risk of self-harm, suicide, or hurting another person:

  • Ask the tough question: “Are you considering suicide?”
  • Listen to the person without judgment.
  • Call 911 or the local emergency number, or text TALK to 741741 to communicate with a trained crisis counselor.
  • Stay with the person until professional help arrives.
  • Try to remove any weapons, medications, or other potentially harmful objects.

If you or someone you know is having thoughts of suicide, a prevention hotline can help. The Suicide and Crisis Lifeline is available 24 hours per day when you call 988. During a crisis, people who are hard of hearing can use their preferred relay service or dial 711 and then 800-273-8255.

Click here for more links and local resources.

Sexual side effects

Antidepressants such as Pristiq may cause sexual side effects. In studies of the drug, males* reported:

  • decreased libido
  • problems getting an erection
  • delayed ejaculation

In studies of the drug, females* reported:

  • not being able to reach orgasm
  • decreased libido

* In this article, we use the terms “male” and “female” to refer to someone’s sex assigned at birth. For information about the difference between sex and gender, see this article.

What might help

Over time, sexual side effects may lessen on their own. Sometimes, switching to a different antidepressant may help. If you experience any sexual side effects while taking Pristiq, tell your doctor. They can suggest ways to help ease sexual side effects.

Nausea

In studies, nausea was a common side effect of Pristiq. By itself, nausea may be considered a mild side effect. But it can be a symptom of withdrawal, which may occur if you stop taking Pristiq suddenly. (For more information, see the “FAQs about Pristiq’s side effects” section above.)

Nausea may also be a symptom of serotonin syndrome. This is a serious condition that can happen when too much serotonin builds up in the body.

Other symptoms of serotonin syndrome include:

  • confusion
  • agitation
  • dizziness
  • racing heartbeat or changes in blood pressure
  • flushing (temporary warmth, redness, or deepening of skin color) or sweating
  • seizure
  • muscle twitching or tremors
  • seeing or hearing things that aren’t real
  • increased body temperature
  • severe vomiting or diarrhea
  • coma
What might help

If you have nausea with Pristiq, the following tips may help ease this side effect:

  • Take your dose with some crackers or toast.
  • Try drinks or foods that contain ginger.
  • Ask your doctor about medications that can help decrease nausea.

If your nausea is severe or occurs with the symptoms of serotonin syndrome listed above, seek immediate medical care.

Headache

Headache was a common side effect in short-term studies of Pristiq. This side effect was usually mild.

This side effect may also occur if you suddenly stop Pristiq. (For more information, see the “FAQs about Pristiq’s side effects” section above.)

Headaches may be a symptom of a low blood level of sodium. This is a side effect of certain antidepressants such as Pristiq, and it can be a serious problem. Older adults (ages 65 years and older) and people who take diuretics may have a higher risk of this side effect. Symptoms to watch out for include:

  • confusion
  • problems with concentration or memory
  • feeling weak and unsteady
  • seeing or hearing things that aren’t real
  • seizure
  • fainting
  • coma
What might help

Mild headaches may lessen a few weeks after starting Pristiq. But if this side effect continues to bother you, talk with your doctor. They may recommend medications to treat your headaches.

If your headaches occur with the other symptoms of a low blood level of sodium listed above, seek immediate medical treatment.

Constipation

Constipation was a common, mild side effect in studies of Pristiq.

What might help

Constipation usually goes away after taking Pristiq for a few weeks. Drinking more water and mild exercise may help with this side effect.

If you experience constipation that becomes severe, talk with your doctor. They may recommend changes in your diet or medications to help relieve this side effect.

Allergic reaction

Like most drugs, Pristiq can cause an allergic reaction in some people. But this side effect wasn’t reported in studies.

Symptoms can be mild to serious and can include:

  • skin rash
  • itchiness
  • flushing (temporary warmth, redness, or deepening of skin color)
  • swelling under your skin, usually in your eyelids, lips, hands, or feet
  • swelling of your mouth, tongue, or throat, which can make it hard to breathe
What might help

If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away. They may suggest treatment options to manage your symptoms. Examples include:

  • an antihistamine you take by mouth, such as Benadryl (diphenhydramine)
  • a product you apply to your skin, such as hydrocortisone cream

If your doctor confirms you’ve had a mild allergic reaction to Pristiq, they’ll decide if you should continue taking it.

If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away. These symptoms could be life threatening and require immediate medical care.

If your doctor confirms you’ve had a serious allergic reaction to Pristiq, they may have you switch to a different treatment.

Keeping track of side effects

During your Pristiq treatment, consider taking notes on any side effects you’re having. You can then share this information with your doctor. This is especially helpful when you first start taking new drugs or using a combination of treatments.

Your side effect notes can include things such as:

  • what dose of the drug you were taking when you had the side effect
  • how soon you had the side effect after starting that dose
  • what your symptoms were
  • how it affected your daily activities
  • what other medications you were taking
  • any other information you feel is important

Keeping notes and sharing them with your doctor will help them learn more about how Pristiq affects you. They can then use this information to adjust your treatment plan if needed.

Pristiq comes with several warnings.

Boxed warning: Risk of suicidal thoughts and actions

Pristiq has a boxed warning for the risk of suicidal thoughts and actions in children, adolescents, and adults ages 24 years and younger. A boxed warning is the most serious warning from the Food and Drug Administration (FDA).

To learn more, see the “Side effects explained” section above.

Other warnings

Pristiq may cause drug-condition interactions. This means that Pristiq may not be right for you if you have certain medical conditions. Other factors may also affect whether Pristiq is a good treatment option for you.

Talk with your doctor about your health history before starting Pristiq. The list below includes factors to consider.

High blood pressure. Pristiq can cause your blood pressure to increase.If you have high blood pressure, your doctor may prescribe medication to treat it before you start taking Pristiq. Then they’ll monitor your blood pressure to make sure it’s well-managed. If your blood pressure remains high, your doctor may adjust your dosage of Pristiq or recommend a different antidepressant.

Heart disease. If you have heart disease, Pristiq may make it worse. Pristiq can increase your blood pressure, which may worsen heart disease. If you have a history of heart disease or high blood pressure, tell your doctor before starting Pristiq treatment.

Stroke or ministroke. Pristiq can increase your blood pressure, so it may increase your risk of stroke if you’ve had one before. If you’ve had a stroke or if you’ve had any problems with high blood pressure, let your doctor know. This will help them determine whether it’s safe for you to take Pristiq.

Bleeding problems. Medications like Pristiq may increase your risk of bleeding. If you take medications that increase bleeding, your risk may be greater. Before you take Pristiq, make sure your doctor knows all of the medications you take.

Angle-closure glaucoma. Pristiq may cause dilation of the pupils in the eye. This can cause an episode of glaucoma in certain people. Because of this, doctors will likely not prescribe Pristiq to anyone with this kind of glaucoma. If you have a history of glaucoma or if you take any eye drops for glaucoma, tell your doctor. They’ll discuss with you treatment options that are safe for you to take.

Mania, hypomania, or bipolar disorder. Pristiq may not be the right medication for people who have had mania, hypomania, or bipolar disorder. It also may not be safe for people who have a family history of these mental health conditions. If you have bipolar disorder, Pristiq can increase your risk of a manic episode. Before you start Pristiq treatment, tell your doctor about any mental health conditions you or close family members have had.

Allergic reaction. If you’ve had an allergic reaction to Pristiq or any of its ingredients, your doctor will likely not prescribe Pristiq. Ask them what other medications are better options for you.

Seizures or epilepsy. Pristiq was not studied in people with a history of seizures or epilepsy. If you’ve ever had a seizure or have epilepsy, tell your doctor. They’ll let you know if Pristiq is safe for you to take.

Low sodium level. Pristiq can lower the blood level of sodium, which can become a serious problem. Older adults (ages 65 years and older) or people who take diuretics may have a higher risk of this side effect. If you are an older adult or take a diuretic, or have had problems with a low sodium level in the past, your doctor will let you know whether it’s safe to take Pristiq.

Liver problems. If you have liver problems, your body may have trouble getting rid of Pristiq. Before you start treatment, tell your doctor about any liver problems you have or have had. They may prescribe a lower dosage of Pristiq.

Kidney problems. If you have kidney problems, your body may have trouble getting rid of Pristiq. Before you start treatment, tell your doctor about any kidney problems you have or have had. They may recommend that you take a lower dosage of Pristiq.

High cholesterol or triglycerides. Pristiq may increase cholesterol or triglycerides in certain people. If you’ve had high cholesterol or triglycerides or take medication to treat these conditions, tell your doctor. They may recommend more frequent blood tests to check levels of these substances while you’re taking Pristiq.

Alcohol and Pristiq

You should not take Pristiq with alcohol. Alcohol may increase your risk of side effects and may make depression worse.

Before you start taking Pristiq, tell your doctor if you drink alcohol. They may suggest ways to stop drinking or recommend a different medication for you.

Pregnancy and breastfeeding while taking Pristiq

Before taking Pristiq, talk with your doctor if you are pregnant or plan to become pregnant. They can help you decide if Pristiq is the best choice for you during this time.

Certain antidepressants can increase the risk of preeclampsia or bleeding complications during pregnancy. Taking Pristiq in the third trimester of pregnancy may cause withdrawal symptoms in your newborn.

If you become pregnant during treatment with Pristiq, ask your doctor about registering with the National Pregnancy Registry for Antidepressants. This registry gathers data from people who’ve taken Pristiq while pregnant. This data can help determine the safety of taking antidepressants such as Pristiq during pregnancy.

Small amounts of Pristiq may pass into breast milk. But it’s not known if Pristiq is safe to take during breastfeeding. If you’re breastfeeding or planning to breastfeed, talk with your doctor about ways to safely feed your child during treatment with Pristiq.

Pristiq may help treat your depression symptoms. Some people have mild side effects from the drug, such as nausea and constipation. More serious side effects from Pristiq aren’t common.

If you have questions about Pristiq’s side effects, talk with your doctor or pharmacist. Here are a few questions to ask about treatment with Pristiq:

  • Is my risk of sexual side effects higher when I first start treatment?
  • Does my risk of nausea and vomiting depend on what dose I take?
  • Does Pristiq have more side effects than other drugs that treat my condition?

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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

What They Are and How to Manage Them

If you have depression, your doctor might suggest Pristiq as a treatment option for you.

Pristiq is a prescription drug that’s used to treat major depressive disorder in adults.

The active ingredient in Pristiq is desvenlafaxine. An active ingredient is what makes a drug work. Pristiq comes as a tablet that you swallow. It’s usually taken long term.

For more information about Pristiq, including details about its uses, see this in-depth article.

Like other drugs, Pristiq can cause mild to serious side effects. Keep reading to learn more.

Some people may experience mild to serious side effects during Pristiq treatment. Examples of Pristiq’s commonly reported side effects include:

  • dizziness
  • trouble sleeping
  • increased sweating
  • loss of appetite
  • nausea*

* To learn more about this side effect, see the “Side effects explained” section below.

Read on to learn about other potential mild and serious side effects of Pristiq.

Pristiq may cause mild side effects. Examples of mild side effects that have been reported with Pristiq include:

  • dizziness
  • vomiting
  • trouble sleeping
  • increased sweating
  • drowsiness
  • loss of appetite
  • anxiety
  • dry mouth
  • sexual side effects*
  • nausea*
  • headache*
  • constipation*
  • mild allergic reaction*

* To learn more about this side effect, see the “Side effects explained” section below.

In most cases, these side effects should be temporary. And some may be easily managed, too. But if you have any symptoms that are ongoing or bother you, talk with your doctor or pharmacist. And do not stop taking Pristiq unless your doctor recommends it.

Pristiq may cause mild side effects other than the ones listed above. See the Pristiq prescribing information for details.

Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. If you’d like to notify the FDA about a side effect you’ve had with Pristiq, visit MedWatch.

Pristiq can cause serious side effects, though these are usually rare. Serious side effects that have been reported with Pristiq are listed below. Some of these side effects were reported in studies of Pristiq. But others were reported after the drug became available on the market.

  • increased blood pressure
  • mania and hypomania, which cause elevated mood
  • serotonin syndrome, resulting from a buildup of the chemical serotonin
  • increased risk of bleeding, which may be life threatening
  • angle-closure glaucoma, a serious eye condition
  • discontinuation syndrome, which causes withdrawal symptoms
  • seizures
  • low level of sodium in the blood
  • risk of suicidal thoughts and actions*
  • severe allergic reaction†‡

* Pristiq has a boxed warning for this side effect. This is the most serious warning from the Food and Drug Administration (FDA). To learn more, see the “Side effects explained” section below.
† To learn more about this side effect, see the “Side effects explained” section below.
‡ An allergic reaction is possible after taking Pristiq. But this side effect wasn’t reported in studies.

If you develop serious side effects while taking Pristiq, call your doctor right away. If the side effects seem life threatening or you think you’re having a medical emergency, immediately call 911 or your local emergency number.

Get answers to some frequently asked questions about Pristiq’s side effects.

Does Pristiq cause weight gain?

It’s possible. In studies of Pristiq, weight gain was not a reported side effect. But after Pristiq was made available on the market, some people who took it reported gaining weight.

It’s important to note that weight changes, including weight gain, can be a symptom of depression.

If you experience weight gain while taking Pristiq, talk with your doctor. They may have tips to help with this side effect.

If I suddenly stop taking Pristiq, will I have withdrawal symptoms?

Yes, it’s possible. Withdrawal symptoms may be a side effect of stopping Pristiq, and they can be mild or serious. Some of the mild symptoms of withdrawal include:

  • nausea
  • sweating
  • dizziness
  • headache
  • trouble sleeping
  • “brain zaps” (feeling an electrical jolt in the head that may travel to other parts of the body)
  • irritability, anxiety, or agitation

Some serious symptoms of withdrawal include:

  • seizure
  • suicidal thoughts
  • severe aggression
  • increased blood pressure
  • blurry vision

These side effects are more likely to happen if you stop taking Pristiq suddenly. If you want to stop taking Pristiq, talk with your doctor first. They’ll likely recommend that you take a smaller dose for a while rather than stopping Pristiq abruptly. It may take several months to stop taking Pristiq completely.

Will my risk of side effects be higher with the 100-mg dose of Pristiq than with lower doses of the drug?

It’s possible. During studies of Pristiq, people took different doses of the drug. The side effects that were reported were the same for each dosage. But more people who took the 100-milligram (mg) dose reported certain side effects than those who took the 50-mg dose. Some of these side effects were:

  • dry mouth
  • sleepiness
  • trouble sleeping
  • certain sexual side effects*
  • nausea*

* To learn more about this side effect, see the “Side effects explained” section below.

Learn more about some of the side effects Pristiq may cause.

Risk of suicidal thoughts and actions

Pristiq carries a boxed warning about the risk of suicidal thoughts and actions in children, adolescents, and adults ages 24 years and younger. A boxed warning is the most serious warning from the Food and Drug Administration (FDA).

Antidepressants such as Pristiq may increase the risk of suicidal thoughts and actions in people under 25 years of age. The FDA has not approved the use of Pristiq in people ages 18 years or younger.

Symptoms of suicidal thoughts and actions include:

  • sudden changes in mood, behaviors, thoughts, or feelings
  • trouble sleeping
  • new or worsened irritability or depression
  • extreme anger, violence, or aggression
  • extreme increase in talking, excitement, and activity, which can result from mania
  • panic attack
  • impulsive behavior
  • thoughts about dying or hurting yourself
  • suicide attempts
What might help

Keep track of how you feel while taking Pristiq. If you experience any of the symptoms listed above while taking Pristiq, tell your doctor right away.

Consider letting people close to you know about this Pristiq side effect and its symptoms. They can also help you watch out for these symptoms.

If you’re 18 to 24 years of age, your doctor may monitor you more closely for symptoms of suicidal thoughts and actions during Pristiq treatment.

Suicide prevention

If you know someone at immediate risk of self-harm, suicide, or hurting another person:

  • Ask the tough question: “Are you considering suicide?”
  • Listen to the person without judgment.
  • Call 911 or the local emergency number, or text TALK to 741741 to communicate with a trained crisis counselor.
  • Stay with the person until professional help arrives.
  • Try to remove any weapons, medications, or other potentially harmful objects.

If you or someone you know is having thoughts of suicide, a prevention hotline can help. The Suicide and Crisis Lifeline is available 24 hours per day when you call 988. During a crisis, people who are hard of hearing can use their preferred relay service or dial 711 and then 800-273-8255.

Click here for more links and local resources.

Sexual side effects

Antidepressants such as Pristiq may cause sexual side effects. In studies of the drug, males* reported:

  • decreased libido
  • problems getting an erection
  • delayed ejaculation

In studies of the drug, females* reported:

  • not being able to reach orgasm
  • decreased libido

* In this article, we use the terms “male” and “female” to refer to someone’s sex assigned at birth. For information about the difference between sex and gender, see this article.

What might help

Over time, sexual side effects may lessen on their own. Sometimes, switching to a different antidepressant may help. If you experience any sexual side effects while taking Pristiq, tell your doctor. They can suggest ways to help ease sexual side effects.

Nausea

In studies, nausea was a common side effect of Pristiq. By itself, nausea may be considered a mild side effect. But it can be a symptom of withdrawal, which may occur if you stop taking Pristiq suddenly. (For more information, see the “FAQs about Pristiq’s side effects” section above.)

Nausea may also be a symptom of serotonin syndrome. This is a serious condition that can happen when too much serotonin builds up in the body.

Other symptoms of serotonin syndrome include:

  • confusion
  • agitation
  • dizziness
  • racing heartbeat or changes in blood pressure
  • flushing (temporary warmth, redness, or deepening of skin color) or sweating
  • seizure
  • muscle twitching or tremors
  • seeing or hearing things that aren’t real
  • increased body temperature
  • severe vomiting or diarrhea
  • coma
What might help

If you have nausea with Pristiq, the following tips may help ease this side effect:

  • Take your dose with some crackers or toast.
  • Try drinks or foods that contain ginger.
  • Ask your doctor about medications that can help decrease nausea.

If your nausea is severe or occurs with the symptoms of serotonin syndrome listed above, seek immediate medical care.

Headache

Headache was a common side effect in short-term studies of Pristiq. This side effect was usually mild.

This side effect may also occur if you suddenly stop Pristiq. (For more information, see the “FAQs about Pristiq’s side effects” section above.)

Headaches may be a symptom of a low blood level of sodium. This is a side effect of certain antidepressants such as Pristiq, and it can be a serious problem. Older adults (ages 65 years and older) and people who take diuretics may have a higher risk of this side effect. Symptoms to watch out for include:

  • confusion
  • problems with concentration or memory
  • feeling weak and unsteady
  • seeing or hearing things that aren’t real
  • seizure
  • fainting
  • coma
What might help

Mild headaches may lessen a few weeks after starting Pristiq. But if this side effect continues to bother you, talk with your doctor. They may recommend medications to treat your headaches.

If your headaches occur with the other symptoms of a low blood level of sodium listed above, seek immediate medical treatment.

Constipation

Constipation was a common, mild side effect in studies of Pristiq.

What might help

Constipation usually goes away after taking Pristiq for a few weeks. Drinking more water and mild exercise may help with this side effect.

If you experience constipation that becomes severe, talk with your doctor. They may recommend changes in your diet or medications to help relieve this side effect.

Allergic reaction

Like most drugs, Pristiq can cause an allergic reaction in some people. But this side effect wasn’t reported in studies.

Symptoms can be mild to serious and can include:

  • skin rash
  • itchiness
  • flushing (temporary warmth, redness, or deepening of skin color)
  • swelling under your skin, usually in your eyelids, lips, hands, or feet
  • swelling of your mouth, tongue, or throat, which can make it hard to breathe
What might help

If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away. They may suggest treatment options to manage your symptoms. Examples include:

  • an antihistamine you take by mouth, such as Benadryl (diphenhydramine)
  • a product you apply to your skin, such as hydrocortisone cream

If your doctor confirms you’ve had a mild allergic reaction to Pristiq, they’ll decide if you should continue taking it.

If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away. These symptoms could be life threatening and require immediate medical care.

If your doctor confirms you’ve had a serious allergic reaction to Pristiq, they may have you switch to a different treatment.

Keeping track of side effects

During your Pristiq treatment, consider taking notes on any side effects you’re having. You can then share this information with your doctor. This is especially helpful when you first start taking new drugs or using a combination of treatments.

Your side effect notes can include things such as:

  • what dose of the drug you were taking when you had the side effect
  • how soon you had the side effect after starting that dose
  • what your symptoms were
  • how it affected your daily activities
  • what other medications you were taking
  • any other information you feel is important

Keeping notes and sharing them with your doctor will help them learn more about how Pristiq affects you. They can then use this information to adjust your treatment plan if needed.

Pristiq comes with several warnings.

Boxed warning: Risk of suicidal thoughts and actions

Pristiq has a boxed warning for the risk of suicidal thoughts and actions in children, adolescents, and adults ages 24 years and younger. A boxed warning is the most serious warning from the Food and Drug Administration (FDA).

To learn more, see the “Side effects explained” section above.

Other warnings

Pristiq may cause drug-condition interactions. This means that Pristiq may not be right for you if you have certain medical conditions. Other factors may also affect whether Pristiq is a good treatment option for you.

Talk with your doctor about your health history before starting Pristiq. The list below includes factors to consider.

High blood pressure. Pristiq can cause your blood pressure to increase.If you have high blood pressure, your doctor may prescribe medication to treat it before you start taking Pristiq. Then they’ll monitor your blood pressure to make sure it’s well-managed. If your blood pressure remains high, your doctor may adjust your dosage of Pristiq or recommend a different antidepressant.

Heart disease. If you have heart disease, Pristiq may make it worse. Pristiq can increase your blood pressure, which may worsen heart disease. If you have a history of heart disease or high blood pressure, tell your doctor before starting Pristiq treatment.

Stroke or ministroke. Pristiq can increase your blood pressure, so it may increase your risk of stroke if you’ve had one before. If you’ve had a stroke or if you’ve had any problems with high blood pressure, let your doctor know. This will help them determine whether it’s safe for you to take Pristiq.

Bleeding problems. Medications like Pristiq may increase your risk of bleeding. If you take medications that increase bleeding, your risk may be greater. Before you take Pristiq, make sure your doctor knows all of the medications you take.

Angle-closure glaucoma. Pristiq may cause dilation of the pupils in the eye. This can cause an episode of glaucoma in certain people. Because of this, doctors will likely not prescribe Pristiq to anyone with this kind of glaucoma. If you have a history of glaucoma or if you take any eye drops for glaucoma, tell your doctor. They’ll discuss with you treatment options that are safe for you to take.

Mania, hypomania, or bipolar disorder. Pristiq may not be the right medication for people who have had mania, hypomania, or bipolar disorder. It also may not be safe for people who have a family history of these mental health conditions. If you have bipolar disorder, Pristiq can increase your risk of a manic episode. Before you start Pristiq treatment, tell your doctor about any mental health conditions you or close family members have had.

Allergic reaction. If you’ve had an allergic reaction to Pristiq or any of its ingredients, your doctor will likely not prescribe Pristiq. Ask them what other medications are better options for you.

Seizures or epilepsy. Pristiq was not studied in people with a history of seizures or epilepsy. If you’ve ever had a seizure or have epilepsy, tell your doctor. They’ll let you know if Pristiq is safe for you to take.

Low sodium level. Pristiq can lower the blood level of sodium, which can become a serious problem. Older adults (ages 65 years and older) or people who take diuretics may have a higher risk of this side effect. If you are an older adult or take a diuretic, or have had problems with a low sodium level in the past, your doctor will let you know whether it’s safe to take Pristiq.

Liver problems. If you have liver problems, your body may have trouble getting rid of Pristiq. Before you start treatment, tell your doctor about any liver problems you have or have had. They may prescribe a lower dosage of Pristiq.

Kidney problems. If you have kidney problems, your body may have trouble getting rid of Pristiq. Before you start treatment, tell your doctor about any kidney problems you have or have had. They may recommend that you take a lower dosage of Pristiq.

High cholesterol or triglycerides. Pristiq may increase cholesterol or triglycerides in certain people. If you’ve had high cholesterol or triglycerides or take medication to treat these conditions, tell your doctor. They may recommend more frequent blood tests to check levels of these substances while you’re taking Pristiq.

Alcohol and Pristiq

You should not take Pristiq with alcohol. Alcohol may increase your risk of side effects and may make depression worse.

Before you start taking Pristiq, tell your doctor if you drink alcohol. They may suggest ways to stop drinking or recommend a different medication for you.

Pregnancy and breastfeeding while taking Pristiq

Before taking Pristiq, talk with your doctor if you are pregnant or plan to become pregnant. They can help you decide if Pristiq is the best choice for you during this time.

Certain antidepressants can increase the risk of preeclampsia or bleeding complications during pregnancy. Taking Pristiq in the third trimester of pregnancy may cause withdrawal symptoms in your newborn.

If you become pregnant during treatment with Pristiq, ask your doctor about registering with the National Pregnancy Registry for Antidepressants. This registry gathers data from people who’ve taken Pristiq while pregnant. This data can help determine the safety of taking antidepressants such as Pristiq during pregnancy.

Small amounts of Pristiq may pass into breast milk. But it’s not known if Pristiq is safe to take during breastfeeding. If you’re breastfeeding or planning to breastfeed, talk with your doctor about ways to safely feed your child during treatment with Pristiq.

Pristiq may help treat your depression symptoms. Some people have mild side effects from the drug, such as nausea and constipation. More serious side effects from Pristiq aren’t common.

If you have questions about Pristiq’s side effects, talk with your doctor or pharmacist. Here are a few questions to ask about treatment with Pristiq:

  • Is my risk of sexual side effects higher when I first start treatment?
  • Does my risk of nausea and vomiting depend on what dose I take?
  • Does Pristiq have more side effects than other drugs that treat my condition?

For tips on managing your mental health, sign up for Healthline’s anxiety and depression newsletter.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

Samyun Wan – scam dangerous to health

Attention: DANGEROUS ADDITIVE!

We receive daily questions from customers about when the so-called Samyun Wan goes on sale. Our answer: never. Here’s why:

> This product is not officially registered in any register of the countries participating in the Customs Union.
> In nature, there is no Certificate of State Registration of such a product, as well as a Certificate of Conformity, and a Declaration of Conformity of the EAC. That is, not a single official document was issued for this product by any of the authorities of Kazakhstan, Belarus and the Russian Federation.
> Based on the previous paragraph, this product is contraband and cannot be sold by any self-respecting store.
> The manufacturer indicated on the package is neither in Indonesia nor in China. That is, the real origin of the product is unknown.
> Packaging does not comply with GOSTs of any developed country. The absence of mandatory storage conditions, barcodes, references to regulatory documents or organizations that are responsible for this product eloquently indicates the counterfeit nature of the additive. That is, it is a fake made by no one knows who, no one knows under what conditions, no one knows from what.
> Ingredients do not list any product that could have any effect on muscle mass gain. That is, the supplement either does not give any weight gain, or contains hidden components, which means it is potentially dangerous to take.


Composition Samyun Wan (a set of useless dietary supplements)

10 seconds of Google and immediately find the nearest seller who generously paints the positive effects of taking this supplement and its composition. Let’s start with the composition, that’s what it is, so we understand the compositions well.

– Shandar ginseng root.
-Let’s start with the fact that there is no “Shandai” ginseng. There is simply no such concept. There is a corresponding region in Dagestan, but, alas, ginseng does not grow there.

Classical ginseng can slightly act as an aphrodisiac, that is, improve potency and slightly stimulate the central nervous system as an adaptogen. As a potency stimulant, it is rather weak and therefore is not prescribed by urologists even to the most suspicious patients, and as a CNS stimulant, it is absolutely ineffective against the background of the most common caffeine. It has absolutely no effect on a set of muscle mass and endurance.

– Rhizome of Atractylodes largehead.
-Unfortunately, there are simply no authoritative sources that would describe this herb. Information on it is found only on sites that sell Chinese herbs of dubious origin. In Western medicine, it is not used at all and is not even mentioned. On Chinese sites, there is no word about “saving energy”, only that this supplement is used to improve bowel movement, that is, a remedy for constipation.

– Astragalus membranous.
– Another additive unknown to classical medicine. It is used only in alternative medicine, that is, by grandmothers-healers. Of the described effects – a decrease in fatigue, while the principle of operation is not described anywhere. The composition is just grass without any special components. An interesting fact: an endangered species listed in the Red Book, that is, it is quite difficult to meet it, and it is very difficult to grow it, because. whimsical. Most likely, it simply does not exist.

– Ginseng root.
– It is not clear why ginseng is mentioned twice, apparently simply because there is nothing more to write.

– Deer antler extract.
– The type of deer is not indicated, but it is most likely about the “antlers” that have set the teeth on edge, which were popular in the early 2000s as a remedy for all diseases. Naturally, time put everything in its place and now no one is looking for or buying this supplement anymore, because. she is absolutely useless. And how can it be effective if the human digestive system simply cannot absorb a product of this kind.

There is nothing else in the composition. Just a collection of dubious herbs and no truly effective ingredient. No creatine, no citrulline, no vitamin-mineral premix, which have been the base for all sports supplements for over 30 years! Not a single component with proven effectiveness, just garbage for gullible people.

Mass Gaining Products Proven to Work

Rated 4.89 out of 5

Halal Creatine Monohydrate

8’770 ₸

The described effects (lie squared)

000 tenge, that’s luck! A cheap product that is superior in effectiveness to all known sports nutrition supplements:

There are already 9 magical effects of this supplement, only points about prolonging life and enhancing potency are missing.

– Promotes 5 to 7 kg mass gain with one can
– When customers buy proven products from us from famous companies and ask how much they can gain “in one can”, we NEVER answer, because. it depends on individual characteristics, nutrition, sleep, lifestyle, hormonal background and so on. We immediately explain that the one who promises you that you will gain N-th number of kilograms is just a charlatan. That is, we boldly declare that the one who wrote this promotion is just a liar.

– Acceleration of recovery after physical exertion.
-Due to what mechanism?

– Improvement of metabolism.
– How can metabolism be improved? There is such a thing as “speed of metabolic processes”, in medicine there is no concept of “bad” or “good” metabolism, each metabolism is good for each individual case and is determined by genetics, as well as general health. In the first case, nothing can be done with him, and in the second, you need to undergo treatment, and obviously, not with such a “drug”.

– Increased energy.
– There is no “energy”. There is functional training and tolerance to physical activity. It is achieved through training and diet/sleep. No other way.

– Increased appetite.
– Appetite is manifested by a decrease in blood glucose levels, if this drug affects the rate of glucose utilization, then this supplement is dangerous to use.

– Strengthening the body.
– Another term from couch doctors who are treated with cupping and urine therapy. There is no such thing as “body strength”. Neither medicine, nor even more so dietology, does not contain this concept. There are no scales and evaluation criteria. The “strength” of the body is simply impossible to feel or measure, there is no device that can determine this very “strength”. Another unfounded assertion.

– Increased immune system. (sic!)
– Seriously, that’s what the author wrote. According to the author, the immune system has a size, apparently, it can be large, sometimes small, sometimes medium or between medium and large. What kind of nonsense you ask? Here we are about the same. Complete nonsense. There is a speed and strength of the immune response, but you can’t buy really effective immunomodulators without a prescription, and it’s hard to find them in a pharmacy. All sorts of cycloferons are drugs with unproven effectiveness, and human immunity is such a complex and poorly studied area that in most cases doctors simply recommend leading a healthy lifestyle without prescribing anything in essence, tk. THERE IS NO PILL THAT WILL STRENGTHEN THE IMMUNE SYSTEM.

– Fight against viral infections.
– We can ask real practitioners about drugs against viruses and here is their answer (in particular, Zhukov N.E. best-selling author in medicine): for herpes and a couple of too cool names; everything else (including BAT for AIDS) is just additional treatment – all these interferons, nucleotides and other poultices are unproven drugs and their significance is usually exaggerated. I’m not talking about homeopathy and dietary supplements, just forget about them.

This drug belongs to the class of dietary supplements, which means that it simply cannot be effective.

– Removes slags.
– Slag does not exist. Medicine does not know such a concept. This term was coined by charlatans to prescribe non-working supplements in order to make money on gullible people. Here is an excerpt from Wikipedia:

“Slag” is a pseudoscientific[1][2] term common in alternative medicine, meaning harmful substances from food and the environment that accumulate in the body[3]. Some representatives of alternative medicine consider the accumulation of toxins as one of the factors in the deterioration of health.

Key words: pseudoscientific (that is, not related to science) and alternative medicine (that is, not medicine at all).

Samyun Wan packaging (clownish design with a claim to traditionality)

Describing the packaging is just a waste of time, but it should be mentioned that the packaging does not comply with the norms of the Republic of Kazakhstan and the Customs Union. There is no information in Russian and Kazakh languages. The manufacturer’s label is incorrect. A certain Wisdom Group is declared by the manufacturer, in the Russian Federation there is a website for such a company, only it deals with building materials from China. Other mentions are that there is a software development team in Chicago with the same name, and there is also a company with the same name in China, except that they sell electronic devices. That is, this company simply does not exist. We can safely assume that Samyun Wan is produced in some kind of basement in violation of sanitary and epidemiological requirements.

Only natural components (and not natural dexamethasone)
and positively negative for health. There are references on the net about Samyun Wan, which contains the synthetic hormone dexamethasone. This is a glucocorticosteroid, it is not the same as a regular anabolic steroid. If anabolic steroids, although harmful, are able to increase muscle mass, then such a drug does not give such effects, providing the opposite. Dexamethasone is used for cerebral edema and among a large list of side effects has the following: it reduces protein synthesis and enhances protein catabolism in muscle tissue, that is, muscle tissue is destroyed. When you take a dexamethasone supplement, you will LOSE muscle mass, not gain it.

Sales points (hucksters selling from apartments)
It was impossible to find a respectable store that would sell this supplement. Still, no one would issue accompanying documents for such products. We decided to check one of these sellers by asking a completely banal question – is there an SGR (certificate of state registration) of this product. The seller, who introduced himself as Ruslan, hesitated, began to ask again what we mean, when we explained what kind of document it was and where to get it, he said that of course it is, just call back in 10 minutes, he will look for it. We did just that, only no one took the phone, however, as well as the next day and a week after that. We tried to WhatsApp the seller, but he blocked us.

For understanding: in our store there are more than 300 items of various products made in the USA, Canada, Poland, Great Britain, Russia, Hungary, and for each of these products there is a SGR with a unique number, which is registered in the unified register of the Customs Union. You can request, we will forward the request to suppliers (importers) and they will provide a scan of the document within 2-3 days from the date of receipt of the application.