Round white 5 325. Ratio-Oxycocet: Understanding the Oxycodone-Acetaminophen Combination Medication
What is Ratio-Oxycocet. How does this combination medication work. What are the potential benefits and risks of using Ratio-Oxycocet. Who should use caution when taking this medication. What are the proper dosage guidelines for Ratio-Oxycocet. How can patients safely store and dispose of this medication. What are the alternatives to Ratio-Oxycocet for pain management.
What is Ratio-Oxycocet and How Does It Work?
Ratio-Oxycocet is a combination medication that contains two active ingredients: oxycodone and acetaminophen. This powerful pain reliever is prescribed for moderate to severe pain management. But how exactly does it work in the body?
Oxycodone, an opioid analgesic, works by binding to specific receptors in the brain and spinal cord, effectively altering the way the body perceives and responds to pain signals. Acetaminophen, on the other hand, is believed to work by inhibiting the production of prostaglandins, substances in the body that cause pain and fever.
Together, these two medications provide a synergistic effect, offering more comprehensive pain relief than either component alone. This combination can be particularly effective for various types of pain, including post-surgical pain, injury-related pain, and chronic pain conditions.
Benefits and Risks of Using Ratio-Oxycocet
While Ratio-Oxycocet can be highly effective for pain management, it’s crucial to understand both its potential benefits and risks. What are the advantages of using this medication?
- Powerful pain relief for moderate to severe pain
- Combination of two effective pain-relieving mechanisms
- Potential for improved quality of life for those suffering from chronic pain
However, like all medications, Ratio-Oxycocet comes with potential risks and side effects. These can include:
- Drowsiness and dizziness
- Constipation
- Nausea and vomiting
- Risk of addiction and dependence
- Potential for liver damage due to acetaminophen content
It’s essential for patients to discuss these risks with their healthcare provider and carefully follow prescribed dosage instructions to minimize potential harm.
Who Should Use Caution with Ratio-Oxycocet?
While Ratio-Oxycocet can be an effective pain management tool for many, certain individuals should exercise caution or avoid its use altogether. Who falls into these categories?
- Individuals with a history of substance abuse or addiction
- People with liver disease or impaired liver function
- Those with respiratory conditions such as asthma or COPD
- Elderly patients, who may be more sensitive to the effects of opioids
- Pregnant or breastfeeding women
It’s crucial for patients to provide a complete medical history to their healthcare provider before starting Ratio-Oxycocet to ensure its safe and appropriate use.
Proper Dosage and Administration of Ratio-Oxycocet
Adhering to proper dosage guidelines is crucial when taking Ratio-Oxycocet. How should patients take this medication?
The typical starting dose for adults is one tablet every 6 hours as needed for pain. However, dosage can vary based on individual factors such as age, weight, and the severity of pain. It’s essential never to exceed the recommended dose, particularly due to the acetaminophen content, which can cause liver damage in high doses.
Patients should take Ratio-Oxycocet exactly as prescribed by their healthcare provider. It can be taken with or without food, but taking it with food may help reduce the risk of stomach upset.
Important Dosage Considerations:
- Never crush, chew, or break the tablets
- Do not increase the dose without consulting a healthcare provider
- Keep track of the timing between doses to avoid accidental overdose
- Be aware of other medications containing acetaminophen to avoid exceeding the daily limit
Safe Storage and Disposal of Ratio-Oxycocet
Proper storage and disposal of Ratio-Oxycocet are crucial for preventing accidental ingestion and potential misuse. How can patients ensure they’re handling this medication safely?
For storage:
- Keep the medication in its original container
- Store at room temperature, away from moisture and heat
- Keep out of reach of children and pets
- Consider using a lockbox for additional security
When it comes to disposal:
- Do not flush unused medication down the toilet
- Check for local drug take-back programs
- If no take-back program is available, mix the medication with an undesirable substance (like used coffee grounds), seal in a plastic bag, and dispose of in household trash
Proper storage and disposal help prevent accidental ingestion, misuse, and environmental contamination.
Potential Drug Interactions with Ratio-Oxycocet
Understanding potential drug interactions is crucial for patients taking Ratio-Oxycocet. What other substances might interact with this medication?
Several types of medications and substances can interact with Ratio-Oxycocet, potentially increasing risks or altering its effectiveness:
- Other opioid medications
- Benzodiazepines
- Alcohol
- Certain antidepressants
- Muscle relaxants
- Some antihistamines
It’s essential for patients to inform their healthcare provider about all medications, supplements, and substances they use to prevent potentially dangerous interactions.
Specific Interaction Concerns:
- Combining Ratio-Oxycocet with other opioids or central nervous system depressants can increase the risk of severe respiratory depression.
- Alcohol can enhance the sedative effects of oxycodone and increase the risk of liver damage due to the acetaminophen content.
- Some antidepressants, particularly MAOIs, can interact dangerously with oxycodone.
Patients should always consult their healthcare provider or pharmacist about potential interactions before starting any new medication or supplement while taking Ratio-Oxycocet.
Recognizing and Managing Side Effects of Ratio-Oxycocet
While Ratio-Oxycocet can be effective for pain management, it’s important for patients to be aware of potential side effects. What are some common side effects, and how can they be managed?
Common side effects may include:
- Drowsiness and dizziness
- Constipation
- Nausea and vomiting
- Dry mouth
- Itching
Most side effects are mild and may decrease over time as the body adjusts to the medication. However, some management strategies can help:
- For constipation: Increase fiber intake, stay hydrated, and consider using a gentle laxative as recommended by a healthcare provider.
- For nausea: Take the medication with food, avoid lying down immediately after dosing, and try ginger tea or other anti-nausea remedies.
- For drowsiness: Avoid driving or operating machinery until you know how the medication affects you.
It’s crucial to report any severe or persistent side effects to a healthcare provider promptly. Patients should seek immediate medical attention if they experience signs of an allergic reaction, severe dizziness, difficulty breathing, or signs of liver problems such as yellowing of the skin or eyes.
Alternatives to Ratio-Oxycocet for Pain Management
While Ratio-Oxycocet can be effective for pain management, it’s not suitable for everyone. What are some alternative options for managing moderate to severe pain?
Depending on the type and severity of pain, healthcare providers might consider several alternatives:
Non-Opioid Medications:
- NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) like ibuprofen or naproxen
- COX-2 inhibitors
- Gabapentin or pregabalin for neuropathic pain
- Topical analgesics for localized pain
Non-Pharmacological Approaches:
- Physical therapy
- Acupuncture
- Cognitive Behavioral Therapy (CBT)
- Mindfulness and meditation techniques
In some cases, a combination of different approaches may provide the most effective pain relief while minimizing the risks associated with opioid medications like Ratio-Oxycocet.
It’s important for patients to work closely with their healthcare providers to find the most appropriate pain management strategy for their individual needs and circumstances. This may involve trying different approaches or combinations of treatments to achieve optimal pain relief with minimal side effects.
Long-Term Use and Addiction Risk of Ratio-Oxycocet
Given the opioid component in Ratio-Oxycocet, there are important considerations regarding long-term use and addiction risk. How can patients and healthcare providers navigate these concerns?
Long-term use of opioid medications like Ratio-Oxycocet can lead to physical dependence and, in some cases, addiction. It’s crucial for patients and healthcare providers to be aware of these risks and take steps to minimize them:
- Regular reassessment of pain levels and medication effectiveness
- Exploring alternative or complementary pain management strategies
- Monitoring for signs of tolerance or increasing dosage needs
- Implementing opioid-sparing techniques when possible
- Being vigilant for signs of misuse or addiction
Healthcare providers may implement strategies such as opioid contracts, regular urine drug screening, and pill counts to help ensure appropriate use of the medication. Patients should be encouraged to communicate openly about their pain levels, any concerns about dependence, and any challenges they face in managing their medication use.
Signs of Potential Misuse or Addiction:
- Taking higher doses than prescribed or more frequent doses
- Seeking prescriptions from multiple doctors (“doctor shopping”)
- Using the medication for reasons other than pain relief (e.g., to relax or get high)
- Continued use despite negative consequences in life or relationships
- Experiencing withdrawal symptoms when trying to stop or reduce use
If patients or their loved ones notice signs of potential misuse or addiction, it’s crucial to seek help promptly. Many resources are available, including addiction specialists, support groups, and rehabilitation programs designed specifically for opioid use disorders.
While Ratio-Oxycocet can be an effective tool for pain management, its use requires careful consideration, ongoing monitoring, and open communication between patients and healthcare providers to ensure safe and appropriate use over time.
Unknown opioid found in fake pain pills
Story highlights
Fake prescription painkillers are the suspected cause of an overdose cluster in Georgia this week
One of the drugs in the pills is still a mystery and may be a new compound
CNN
—
Two synthetic opioids have been found in fake prescription pills suspected to have caused a cluster of overdoses this week in Georgia, including four deaths, according to a statement from the Georgia Bureau of Investigation.
One of the drugs is still unidentified and may be a new compound, according to a GBI representative.
“The fact that the GBI Crime Lab has never seen it is a very bold statement,” said Nelly Miles, director of the GBI Office of Public Affairs and a forensic chemist by training. “We’re essentially working it up from scratch.”
The unknown opioid is a modified type of fentanyl that the GBI Crime Lab had never seen, the bureau said. The pills were made to resemble the prescription painkiller Percocet and sold on the street, according to state officials.
Miles said synthetic drugs like this one are coming in from overseas, where fentanyl molecules are altered slightly in an effort to skirt US laws. Then, they may be packed into pill presses in the United States, she said.
Courtesy Bibb County Sheriff’s Office
Overdose cluster in Georgia linked to mystery pill
Fentanyl is 50 to 100 times more potent than the drug morphine, and experts say some fentanyl-like molecules can be far more potent. Further testing is required to verify the identity of the new drug, the bureau said.
The second opioid found was a known synthetic drug, Miles said, but its name is being withheld until the full analysis of both drugs is complete. This could take days, she said.
cms.cnn.com/_components/paragraph/instances/paragraph_06734C02-9C09-9198-449C-88A4E8B5ABA8@published” data-editable=”text” data-component-name=”paragraph”>Those who overdosed thought they were swallowing Percocet, but the overdose symptoms were “much more severe in onset,” Dr. Christopher Hendry, chief medical officer of Navicent Health, said Tuesday. Navicent Health was one of three hospitals in Georgia known to have received the overdose patients.
“Percocet” had been stamped in capital letters on one side of the pills, the Bibb County Sheriff’s Office said Wednesday. On the other side, the pills are imprinted with the numbers “10/325,” usually an indication of medication dosage. Investigators noticed that the imprints on the counterfeit pills were made “at an angle” and not as deep as the manufacturer’s pills.
Georgia Bureau of Investigation
‘Grey death’: The powerful street drug that’s puzzling authorities
Over two dozen people are thought to have overdosed over three days, including the four deaths, according to a representative for the Georgia Department of Public Health. But toxicology results are still pending, and these numbers are “very fluid,” the spokeswoman said.
The patients, mostly brought in by ambulance, appeared sleepy, had slurred speech and had difficulty breathing, Hendry said. These symptoms led doctors at several Georgia hospitals to suspect opioid overdose.
Other street drugs – such as the opioid concoction known as “grey death” – have recently been linked to overdoses in Georgia and other parts of the South.
There were about 1,300 overdose deaths in Georgia in 2015, according to the US Centers for Disease Control and Prevention.
Follow CNN Health on Facebook and Twitter
Bibb County Sheriff David Davis said Tuesday that he suspected “someone has developed this particular pill … and is passing it off as a prescription medicine. ” Thursday’s announcement confirms that theory.
Bibb County officers have been following leads and tips, but the investigation is ongoing, the sheriff’s office confirmed. No arrests have been made.
“The individuals that are involved in the drug trade, this may be their newest product,” Davis said Tuesday, urging people to come forward with more information or turn themselves in.
“We need to know who’s putting this poison in the community right now. ”
CNN’s Kaylee Hartung contributed to this story.
ratio-Oxycocet | RxHealthMed
Medication Search
Explore the medications listed in our database.
ratio-Oxycocet
Common Name:
oxycodone – acetaminophen
How does this medication work? What will it do for me?
This combination product contains two medications: oxycodone and acetaminophen. Acetaminophen belongs to the group of medications called analgesics (pain relievers) and antipyretics (fever reducers). Oxycodone belongs to the group of medications called narcotic analgesics. Oxycodone – acetaminophen is used to relieve moderate to moderately severe pain, including conditions associated with fever.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
What form(s) does this medication come in?
Each white, round, biconvex tablet, imprinted with “TEC” on one side and single score on the other side, contains oxycodone HCl 5 mg and acetaminophen 325 mg. Nonmedicinal ingredients: colloidal silicon dioxide, crospovidone, magnesium stearate, microcrystalline cellulose, povidone, pregelatinized cornstarch, sodium starch glycolate, and stearic acid.
How should I use this medication?
The dosage varies according to each individual and can be affected by the severity of the pain as well as each person’s response to the medication.
The usual recommended adult dose of full-strength oxycodone – acetaminophen (each tablet contains 5 mg oxycodone and 325 mg acetaminophen) is one tablet every 6 hours as needed for pain. Full-strength oxycodone – acetaminophen is not recommended for people under 18 years of age.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
This medication may be habit-forming if taken for long periods of time. Do not stop taking this medication without talking with your doctor. If this medication is stopped suddenly, you may experience withdrawal symptoms such as anxiety, sweating, trouble sleeping, shakiness, nausea, tremors, diarrhea, or hallucinations. If you plan on stopping the medication, your doctor may want you to reduce the dose gradually to reduce the severity of withdrawal effects.
It is important to take this medication exactly as prescribed by your doctor. If your doctor has told you to take this medication on a regular basis and you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
This medication is available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms listed here. The forms available for the specific brand you have searched are listed under “What form(s) does this medication come in?”
Do not dispose of medications in wastewater (e. g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Who should NOT take this medication?
Oxycodone – acetaminophen should not be taken by anyone who:
- is allergic to oxycodone, acetaminophen, or to any of the ingredients of the medication
- has a seizure disorder
- has preexisting respiratory depression
- has status asthmaticus (unresponsive asthma)
What side effects are possible with this medication?
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
- constipation
- dizziness
- drowsiness
- itching
- lightheadedness or feeling faint
- mood changes
- nausea
- vomiting
Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
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|
Stop taking the medication and seek immediate medical attention if any of the following occur:
- convulsions (seizures)
- signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)
- signs of breathing problems (e.g., shallow, irregular breathing, or slow or troubled breathing)
- symptoms of overdose (e.g., cold, clammy skin, abnormally slow or weak breathing, severe dizziness, confusion, slow heartbeat, or extreme drowsiness)
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Are there any other precautions or warnings for this medication?
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
HEALTH CANADA ADVISORY
September 15, 2016
Health Canada has issued new restrictions concerning the use of acetaminophen. To read the full Health Canada Advisory, visit Health Canada’s web site at www.hc-sc.gc.ca.
A previous advisory on acetaminophen was issued on July 9, 2015. To read the full Health Canada Advisory, visit Health Canada’s web site at www.hc-sc.gc.ca.
Abdominal conditions: Oxycodone may make the diagnosis of abdominal conditions more difficult or it may worsen these conditions. People with abdominal conditions such as inflammatory or obstructive bowel disease, acute cholecystitis, or pancreatitis should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Breathing: Oxycodone can suppress breathing. People at risk for breathing difficulties, such as asthma, should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Dependence and withdrawal: This medication contains oxycodone. Physical dependence, psychological dependence, and abuse have occurred with the use of oxycodone. People with a history of past or current substance use problems may be at greater risk of developing abuse or addiction while taking this medication. Abuse is not a problem with people who require this medication for pain relief. If this medication is stopped suddenly, you may experience withdrawal symptoms such as anxiety, sweating, trouble sleeping, shaking, pain, nausea, tremors, diarrhea, and hallucinations. If you have been taking this medication for a while, it should be stopped gradually as directed by your doctor.
Drowsiness/reduced alertness: This medication may cause drowsiness. Do not drive, operate machinery, or perform other potentially hazardous tasks until you have determined how this medication affects you.
Head injury: People with head injuries or increased pressure in the head may have a higher risk of experiencing side effects (breathing problems) or worsening of their condition while taking this medication. These people should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Kidney function: People with kidney disease or reduced kidney function should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Liver function: Acetaminophen can cause decreased liver function. People with liver disease or reduced liver function should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Other medical conditions: People about to undergo surgery of the biliary tract should use caution while taking oxycodone as it may worsen their condition. Oxycodone will worsen the effects of acute alcohol intoxication and delirium tremens.
As well, people with low thyroid (hypothyroidism), Addison’s disease, benign prostatic hypertrophy (enlarged prostate), urethral stricture, decreased function of the adrenal glands, or porphyria should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Seizures: This medication may cause seizures, especially when higher doses are used or when taken with other medications that may increase the risk of seizures such as:
- cyclobenzaprine
- monoamine oxidase inhibitors (MAOIs; e.g., phenelzine, tranylcypromine)
- neuroleptics (e.g., haloperidol, quetiapine, olanzapine, resperidone)
- opioids (e.g., morphine, codeine, oxycodone)
- promethazine
- selective serotonin reuptake inhibitors (SSRIs; e.g., paroxetine, fluoxetine, citalopram)
- tricyclic antidepressants (TCAs; e.g., amitriptyline, imipramine)
The risk of seizures is also higher for people with epilepsy, a history of seizures, or who are at risk of seizures (e.g., people with head trauma).
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: This medication passes into breast milk. If you are a breast-feeding mother and are taking oxycodone and acetaminophen, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using full-strength oxycodone – acetaminophen have not been established for children. (In the case of Percocet® Demi, the safety and effectiveness have not been established for children under 6 years old.)
Seniors: Seniors who take this medication may be more likely to experience side effects or worsening of preexisting medical conditions.
What other drugs could interact with this medication?
There may be an interaction between oxycodone – acetaminophen and any of the following:
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If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
All material copyright MediResource Inc. 1996 – 2021. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/ratio-Oxycocet
Neon-Night Duralyite LED, glow with dynamics (3W), 220V, 13 mm 121-325
Neon-Night Duralyite LED, 220V, 220V, 13 mm 121-325
Main durableon-night Dudidodode , glow with dynamics (3W), 220V, 13 mm 121-325
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Neon-night 121-325
LED Duralight, glow with dynamics (3W), white, 220V, diameter 13 mm, coil 100m, NEON-NIGHT
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Description Neon night 121-325
White duralight for 220v 100 m . Duralight-chasing round LED, dia=13 mm, 3 cores, 2 channels, 240 V, 2.4 W/m, cutting module 4 m, diode pitch 2.77 cm, winding 100 m
Includes 1 connection kit, max connected length 120m.
Specifications Neon-night 121-325
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Dynamics
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37 cm - Packing height
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22 cm - Volume weight
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100 - Power
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Yes
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Dynamics
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Neon-night LED Duralight, glow with dynamics (3W), 220V, 13 mm 121-325
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LED Duralight, glow with dynamics (3W), white, 220V, diameter 13 mm, coil 100m , NEON-NIGHT
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Cord LED Duralight chasing round 13mm white. 2.4W/m 220V IP54 (pack. 100 m) NEON-NIGHT 121-325
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