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Side effects of echinacea goldenseal: Echinacea – Side Effects, Interactions, Uses, Dosage, Warnings


Echinacea: What Should I Know About It?

Echinacea is a flowering plant that grows in the U.S. and Canada. It is also called coneflower. It is a member of the daisy family of plants. Echinacea has been a popular herbal remedy for centuries. Today, it is often used to prevent or treat viruses that cause colds, sore throats, or the flu.

You can find echinacea products in most drug stores or health food stores. It comes in teas, capsules, pills, liquid extracts, or dried herbs. It is one of the most popular herbs in the United States.

Path to improved health

Many people use echinacea as a dietary supplement for infections such as the common cold. They believe it stimulates the immune system. This helps the body do a better job fighting the infection. This can result in the sickness not lasting as long. Some people take it when they are well to prevent getting an infection.

If you want to treat your cold or flu with echinacea, talk to your family doctor first. Also, make sure you do your research. The FDA does not have to approve dietary supplements before they are sold. In some supplements, the ingredients do not match what the label says. Find a company that quality tests its products. Then you will know you are taking the right thing.

Read the package label carefully. Echinacea can come in many different strengths and dosages. It can also come mixed with other supplements. Follow the directions on the package. Only take the recommended dosage. Taking more than the recommended amount can be dangerous.

Most brands say you should avoid taking echinacea on an empty stomach. They recommend taking it with food or a large glass of water. Don’t take echinacea for more than a few weeks. The long-term safety has not been studied thoroughly.

Talk to your doctor before taking echinacea or other supplements. He or she can tell you if it will interfere with any other medicines you take. They can also recommend what dosage you should take.

Store all herbal products out of reach and out of sight of young children. Keep them in a cool, dry place so they do not lose effectiveness. Do not store them in bathrooms, which get hot and humid.

Things to consider

Does it work?

Many studies have been done on echinacea’s effect on the common cold. So far, researchers have not found conclusive evidence on its effectiveness. They don’t believe that taking it after you come down with a cold will shorten the time you are sick. Taking it when you are well may slightly reduce your chances of catching a cold.

What are the side effects?

Echinacea can cause minor side effects. These can include an upset stomach, nausea, and dizziness. Serious side effects include allergic reactions such as rash, swelling, and difficulty breathing. It can also worsen asthma symptoms. Talk to your doctor right away about any side effects you are having.

Some people are allergic to plants in the daisy family. These could include daisies, ragweed, marigolds, or chrysanthemums. This may put you at more risk of having an allergic reaction to echinacea.

Who should not take echinacea?

Echinacea is generally safe, but not for everyone. Do not take echinacea if you have any of the following conditions:

In addition, you should not take echinacea if you take immunosuppressants. It may interact with these medicines.

Talk to your doctor before taking echinacea if any of the following apply to you.

  • You take other medicines regularly or are being treated for a chronic condition. Echinacea may interact with other medicines. It could reduce their effectiveness or cause unwanted side effects.
  • You drink alcohol, smoke, or use illegal drugs. These substances may affect the way echinacea works.
  • You are pregnant or breastfeeding.

Questions to ask your doctor

  • Will echinacea help my cold?
  • Is it safe for me to take it?
  • What is the best dosage for me?
  • How long should I take it?
  • What else can I do to ease my symptoms or shorten the duration of my cold?


National Center for Complementary and Integrative Health, Echinacea

Copyright © American Academy of Family Physicians

This information provides a general overview and may not apply to everyone. Talk to your family doctor to find out if this information applies to you and to get more information on this subject.

Goldenseal – an overview | ScienceDirect Topics

IV. Goldenseal (

Hydrastis canadensis)

Goldenseal is following in the footsteps of American Ginseng (Panax quinquefolius) in terms of plant demographics (reduced wild populations), governmental status (both now regulated in Appendix II of the Convention for International Trade in Endangered Species of Wild Fauna and Flora (CITES)), and by way of rising popularity and escalating price. However, Ginseng is widely cultivated, while Goldenseal cultivation is poorly understood and lags far behind demand. Cultivation of Goldenseal is unquestionably the most significant current herbal agricultural opportunity, but is a path fraught with challenges. United Plant Savers (UpS) is sponsoring ongoing experimentation designed to determine sustainable wild-harvesting techniques and also to define preferred cultivation scenarios. Experimentation is taking place at the UpS Botanical Sanctuary in Rutland, Ohio. Results are reported on an ongoing basis in the ‘United Plant Savers Newsletter’.3

As with cultivation of any forest-dependent species, successful cultivation of Goldenseal requires exact conditions of shade, soil and season. Choosing a site within the hardwood forest and within the original distribution range of the plant is more likely to prove successful than attempts to field cultivate the plant under shadecloth or lath, or to grow it in woods outside its native range. As one gets further away from native ecology, more problems tend to occur, and thus more time, money and energy go into adapting the environment to the plant. Ideally, one grows the plant where the right conditions already exist.

Monocropping in the forest may cause problems such as runaway disease and insect infestation. Alternaria fungus and Goldenseal mites are cases in point. Creating a diverse cropping system, where beds of the main crop are interspersed with plantings of their natural companions, helps the plants sequester soil bacteria and fungi, which assist in nutrient assimilation and protect the plant from insects, parasites and disease organisms. Good candidates for intercropping with Goldenseal are Jewel Weed (Impatiens spp.), Bloodroot (Sanguinaria canadensis), Black Cohosh (Cimicifuga racemosa) and Wild Yam (Dioscorea villosa.) The woody species Spicebush (Lindera benzoin) and Paw Paw (Asimina triloba) may prove useful in further shading the understory. Just as healthy natural ecologies are characterized by the diversity of their plant life, a diversity of plantings in the agroforest contribute to the rapid growth and disease resistance of crop plants.

Cultivation of goldenseal from seed is challenging, but this practice also yields several advantages. Genetic diversity is enhanced, and seedlings are more disease resistant than plants grown from cuttings. A single mature plant may be dug and the rhizome divided into three or four new plants, but that same plant, if allowed to go to seed, can produce approximately thirty new individuals on a yearly basis.

The seed is washed from the ripe fruit in the late summer and sown as soon as possible into prepared beds, under the forest canopy or in the shade garden. Initial germination occurs the following spring, with ongoing germination in the spring of the second year. Seedlings may be grown at close spacing for two years, then transplanted in the fall to a wider spacing, attaining maturity in seven years.

To propagate by root cutting, each mature rhizome is divided into three or more cuttings, which are planted at 12-inch centers in the fall or very early spring. The first year of growth from cuttings is usually a bit weak, typified by attrition of the rhizome, early dormancy and potential for fungal infection. This may be avoided, in part, by planting root cuttings in the fall, not the spring. Further protection from fungal disease is afforded by planting at a wider spacing, thereby improving air circulation around the plants.

The lateral rootlets bear reproductive nodules, which serve to spread the plant in nature. Masses of free rootlets found in Goldenseal shipments may be planted in flats, or the nodule-bearing rootlets may be removed from rhizome cuttings and planted separately in flats. These produce hardy plants that may be transplanted out after a year of containerized growth.

Facts on Echinacea & Goldenseal | Healthy Eating

Echinacea and goldenseal are sometimes combined and marketed as a supplement to support your immune system. While the effect may be true for echinacea, the active ingredient in goldenseal does not impact the immune system. Goldenseal is dangerous for pregnant and breast-feeding women, and both herbs may interact with prescription medications, so consult your health-care provider before taking these supplements.

Echinacea Basics

Echinacea, also known as purple coneflower, belongs to the daisy family and includes nine different species. Laboratory tests show that it stimulates the immune system by increasing the production of cells that fight bacteria and infections, but research continues to explore exactly how it works. Echinacea significantly reduces the severity of cold symptoms and may help you get over a cold faster, but it doesn’t prevent colds, according to New York University Langone Medical Center.

Echinacea Evidence

In the December 2010 issue of the “Annals of Internal Medicine,” researchers reported that echinacea did not affect the duration or severity of the common cold in their study. But it did successfully reduce the number and length of colds in a 2012 study published in “Evidence-Based Complementary and Alternative Medicine.” Contradictory studies may be explained by differences in the way the study preparations are made. “Cochrane Database of Systematic Reviews” reported that the ingredients in echinacea preparations vary depending on the species and the part of the plant used. Evidence to date indicates that using the above-ground portion or whole plant extract from the species Echinacea purpurea works the best.

Goldenseal Basics

You can tell from goldenseal’s various names — turmeric root and goldenroot — that the root is the part used for medicinal purposes. Goldenseal contains a substance called berberine that kills bacteria and fungi. Research shows, but does not yet prove, that berberine may lower blood pressure. When used topically or as a gargle for a sore throat, it may help wounds heal and prevent infections, but insufficient research exists to support its effectiveness. Goldenseal is often sold with echinacea, but as of 2013, no evidence existed to show that it increases immunity or helps treat colds.

Health Warnings

Women who are pregnant should never take goldenseal because it may harm the baby or stimulate contractions; breast-feeding women should also avoid it. Echinacea is generally considered safe, but may cause side effects, such as nausea, vomiting, abdominal pain and diarrhea. If you have allergies to ragweed, daisies or marigolds, you may also be allergic to echinacea. It can slow down the absorption of caffeine, making you jittery from excess caffeine in your system. In addition, echinacea may worsen some autoimmune conditions, including rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus.

Consumer Warnings

A 2003 survey of echinacea products found that 10 percent of the supplements contained no echinacea and half did not accurately label the species used. More than half did not contain the amount of ingredients as stated on the label. Look for the USP Verified mark on the products you buy, which indicates the supplement was tested for quality.



Writer Bio

Sandi Busch received a Bachelor of Arts in psychology, then pursued training in nursing and nutrition. She taught families to plan and prepare special diets, worked as a therapeutic support specialist, and now writes about her favorite topics – nutrition, food, families and parenting – for hospitals and trade magazines.

Echinacea – Susan G. Komen®

What is it?

Echinacea (E. angustifolia, E. purpurea, E. pallida.) are plants related to sunflowers and ragweed. The leaf, flower, and root are used as medicine.

Echinacea species are native to areas east of the Rocky Mountains in the United States. Echinacea seems to activate chemicals in the body that decrease inflammation. It might also increase the body’s immune system.

Echinacea is most commonly used for the common cold and other infections, but there is no good scientific evidence to support most of these uses. There is also no good evidence to support using echinacea for COVID-19.

It is effective?

Natural Medicines rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.

Possibly Effective for …
  • Common cold. Taking echinacea by mouth while still healthy might help prevent some colds in adults, but the benefit is probably small. Taking echinacea after catching a cold doesn’t seem to improve symptoms. It isn’t clear if echinacea is helpful in children.

There is interest in using echinacea for a number of other purposes, but there isn’t enough reliable information to say whether it might be helpful.

How does it work?

Is there concern for the safety of its use?

When taken by mouth: Echinacea is likely safe for most people in the short-term. Various echinacea products have been used safely for up to 10 days. Some products, such as Echinaforce (A. Vogel Bioforce AG), have been used safely for up to 6 months.

The most common side effects are stomach pain, constipation, diarrhea, heartburn, vomiting, and rash. Allergic reactions might occur in some people, especially in people who are allergic to ragweed, mums, marigolds, or daisies.

When applied to the skin: Echinacea is possibly safe when used short-term. A cream (Linola Plus Cream) containing echinacea has been used safely for up to 12 weeks. Applying echinacea to the skin might cause redness, itchiness, or a rash.

Special Precautions & Warnings:

Pregnancy: Echinacea is possibly safe when taken by mouth for up to 7 days when pregnant. There isn’t enough reliable information to know if using echinacea for longer than 7 days is safe.

Breast-feeding: There isn’t enough reliable information to know if echinacea is safe to use when breast-feeding. Stay on the safe side and avoid use.

Children: Echinacea is possibly safe when taken by mouth or applied to the skin for up to 10 days. Taking echinacea by mouth seems to be safe in most children ages 2-11 years, but rashes due to an allergic reaction can occur. There is some concern that allergic reactions to echinacea could be more severe in some children.

An inherited tendency toward allergies (atopy): People with this condition are more likely to develop an allergic reaction to echinacea. It’s best to avoid exposure to echinacea if you have this condition.

“Auto-immune disorders” such as such as multiple sclerosis (MS), lupus (systemic lupus erythematosus, SLE), rheumatoid arthritis (RA), a skin disorder called pemphigus vulgaris, or others: Echinacea might have an effect on the immune system that could make these conditions worse. Don’t take echinacea if you have an auto-immune disorder.

Are there any drug interactions?


Interaction Rating=Moderate Be cautious with this combination.

Echinacea might decrease how quickly the body breaks down caffeine. Taking echinacea along with caffeine might increase levels of caffeine and increase the risk of side effects from caffeine, such as jitteriness, headache, and fast heartbeat.

Darunavir (Prezista)

Interaction Rating=Minor Be watchful with this combination.

Echinacea might affect how quickly the body breaks down darunavir. Taking echinacea along with darunavir might increase the risk of side effects or decrease the effects of darunavir. But it’s not clear if this is a big concern.

Docetaxel (Taxotere)

Interaction Rating=Minor Be watchful with this combination.

Echinacea might affect how quickly the body breaks down docetaxel. Taking echinacea along with docetaxel might increase the risk of side effects or decrease the effects of docetaxel. But it’s not clear if this is a big concern.

Etoposide (VePesid)

Interaction Rating=Moderate Be cautious with this combination.

Echinacea might decrease how quickly the body breaks down etoposide. Taking echinacea along with etoposide might increase the side effects of etoposide.

Etravirine (Intelence)

Interaction Rating=Minor Be watchful with this combination.

Echinacea might affect how quickly the body breaks down etravirine. Taking echinacea along with etravirine might increase the side effects or decrease the effects of etravirine. But it’s not clear if this is a big concern.

Lopinavir / Ritonavir (Kaletra)

Interaction Rating=Minor Be watchful with this combination.

Echinacea might affect how quickly the body breaks down lopinavir / ritonavir. Taking echinacea along with lopinavir / ritonavir might increase the side effects or decrease the effects of lopinavir / ritonavir. But it’s not clear if this is a big concern.

Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates)

Interaction Rating=Moderate Be cautious with this combination.

Some medications are changed and broken down by the liver. Echinacea might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates)

Interaction Rating=Moderate Be cautious with this combination.

Some medications are changed and broken down by the liver. Echinacea might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Medications that decrease the immune system (Immunosuppressants)

Interaction Rating=Moderate Be cautious with this combination.

Echinacea can increase the activity of the immune system. Some medications, such as those used after a transplant, decrease the activity of the immune system. Taking echinacea along with these medications might decrease the effects of these medications.

Midazolam (Versed)

Interaction Rating=Minor Be watchful with this combination.

Echinacea seems to affect how quickly the body breaks down midazolam. Taking midazolam with echinacea might increase the side effects or decrease the effects of midazolam.

Warfarin (Coumadin)

Interaction Rating=Minor Be watchful with this combination.

Warfarin is used to slow blood clotting. Echinacea might increase the breakdown of warfarin and decrease how well warfarin works. This might increase your risk of having a clot. Be sure to have your blood checked regularly. The dose of your warfarin might need to be changed.

Are there any interactions with herbs and supplements?

There are no known interactions with herbs and supplements.

Are there any interactions with food?

There are no known interactions with foods.

What dose is used?

Echinacea is available in many different types of products, including supplements, liquids, creams, mouthwashes, and throat sprays. Doses vary widely depending on the type of product used. Speak with a healthcare provider to find out what type of product and dose might be best for a specific condition.

By what other names is the product known?

American Cone Flower, Black Sampson, Black Susans, Brauneria Angustifolia, Brauneria Pallida, Brauneria Purpurea, Comb Flower, Coneflower, Echinacea Angustifolia, Echinacea Pallida, Echinacea Purpurea, Echinacea Serotine, Echinacea Speciose, Echinaceawurzel, Échinacée, Échinacée Angustifolia, Échinacée Pallida, Échinacée Pourpre, Échinacée Purpurea, Equinácea, Fleur À Hérisson, Hedgehog, Helichroa Purpurea, Igelkopfwurzel, Indian Head, Kansas Snakeroot, Narrow-Leaved Echinacea, Narrow-Leaved Purple Coneflower, Narrow-Leaved Purple Cone Flower, Pale Coneflower, Pale Flower Echinacea, Pale Purple Coneflower, Purple Coneflower, Purple Cone Flower, Purpursonnenhutkraut, Purpursonnenhutwurzel, Racine D’echininacea, Red Sunflower, Rock-Up-Hat, Roter Sonnenhut, Rudbeckia Purpurea, Rudbeckie Pourpre, Schmallblaettrige Kegelblumenwurzel, Schmallblaettriger Sonnenhut, Scurvy Root, Snakeroot, Sonnenhutwurzel.

Natural Medicines disclaims any responsibility related to medical consequences of using any medical product. Effort is made to ensure that the information contained in this monograph is accurate at the time it was published. Consumers and medical professionals who consult this monograph are cautioned that any medical or product related decision is the sole responsibility of the consumer and/or the health care professional. A legal License Agreement sets limitations on downloading, storing, or printing content from this Database. Except for any possible exceptions written into your License Agreement, no reproduction of this monograph or any content from this Database is permitted without written permission from the publisher. Unlawful to download, store, or distribute content from this site.

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© Copyright 1995-2021. Therapeutic Research Faculty, publishers of Natural Medicines, Prescriber’s Letter, and Pharmacist’s Letter. All rights reserved.

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Echinacea | aidsinfonet.org | The AIDS InfoNet

Fact Sheet 726




Echinacea is a flowering plant. It is sometimes called Purple Coneflower. It grows mainly in Europe and the North America. There are several closely related species: Echinacea purpurea, angustifolia, and pallida. They have slightly different medicinal properties. Echinacea purpurea seems more active in the test tube. Echinacea angustifolia appears more effective in people.

Echinacea was the main medicinal herb used by Native Americans in the Great Plains region. Since the late 1930s, German researchers have studied echinacea and its effects on the immune system. Echinacea is one of the most frequently sold herbs in the United States.

The German government has approved Echinacea pallida root and Echinacea purpurea leaf for use against colds, flu, and chronic respiratory or urinary infections. Many studies support its use. However, a US study in 2006 found no benefits from one particular preparation.



Advocates of Echinacea suggest drinking it from small batches made from herbs less than one year old. Echinacea is available in capsules containing a powder of the dried plant or root, and also as a tincture (an alcohol-based preparation). In some cases, people drink pressed juice from fresh plants. For treating skin conditions, special preparations containing pressed juice are used.

The suggested dosage of echinacea depends on which species and which parts of the plant were used. In general, it should not be used for more than 1-2 weeks at a time.



The major use of echinacea is to treat colds and flu. It is also used for urinary tract infections, skin wounds that aren’t healing well, and skin conditions such as psoriasis and eczema.

Echinacea stimulates the immune system. It promotes CD4 cell activation and increases the activity of the immune system. It helps white blood cells attack germs. These effects may decrease if people take echinacea for more than a few weeks.

Echinacea is generally not recommended for use by people with diseases of the immune system such as HIV, multiple sclerosis, or tuberculosis. The German government recommends against using echinacea if you have these conditions. Some researchers believe that echinacea could actually worsen these immune system problems.



Many people with HIV have used echinacea because it stimulates the immune system, or for short-term treatment of colds and the flu. The use of echinacea for people with HIV is controversial.

Some doctors believe that it is not a good idea to stimulate the immune system in people who have some type of immune disorder. Increasing the activation of CD4 cells could give HIV more “target cells” to infect. Other doctors believe that some parts of the immune system are already overactive, causing damage to healthy cells and tissues.

They are also concerned about an animal study showing that echinacea increased levels of tumor necrosis factor alpha (TNF-alpha), a substance produced by the immune system to kill unhealthy cells. High levels of TNF-alpha have been linked to the progression of HIV disease.

Unfortunately, as with most herbal products, there is no careful research in people with HIV. There is no published research to document any dangerous results from the use of echinacea by people with HIV. There is no research on the use of echinacea by pregnant women. They should be careful with tinctures due to their high alcohol content.

Some researchers believe that short-term use of echinacea (up to two weeks) to treat colds or flu does not present any serious risks to people with HIV. However, both AIDS researchers and herbalists warn against long-term use of echinacea.



There are no known side effects from internal or external use of echinacea. The warnings about negative effects of echinacea use in people with immune disorders are based on laboratory studies. There are no human studies that document these side effects.



Most interactions between herbs and medications have not been carefully studied. Echinacea has been shown to reduce blood levels of some antiretroviral medications. However, none of these interactions appear to be significant or to require dose adjustments. Tell your doctor if you are using herbal supplements.



Echinacea (purple coneflower) is a flowering plant used for respiratory problems and to stimulate the immune system. It is a very popular herb in the United States. There are hundreds of published research studies on echinacea, mostly done in Europe. These studies document echinacea’s effects on the immune system and its benefits for treating colds and flu.

Some researchers believe that echinacea’s effects on the immune system might cause problems for people with HIV. However, there are no published studies showing any harmful effects from echinacea. There may be no risk from using echinacea for less than two weeks.



Uses, Benefits, Side Effects, Dose, Precautions & Warnings

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Bhowmick, S. K., Hundley, O. T., and Rettig, K. R. Severe hypernatremia and hyperosmolality exacerbated by an herbal preparation in a patient with diabetic ketoacidosis. Clin Pediatr (Phila) 2007;46(9):831-834. View abstract.

Bolle P, Cometa MF, Palmery M, and et al. Response of rabbit detrusor muscle to total extract and major alkaloids of Hydrastis canadensis. Phytotherapy Research 1998;12:S86-S88.

Cheng, Z., Pang, T., Gu, M., Gao, A. H., Xie, C. M., Li, J. Y., Nan, F. J., and Li, J. Berberine-stimulated glucose uptake in L6 myotubes involves both AMPK and p38 MAPK. Biochim. Biophys.Acta 2006;1760(11):1682-1689. View abstract.

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Chun YT, Yip TT, Lau KL, and et al. A biochemical study on the hypotensive effect of berberine in rats. Gen Pharmac 1979;10:177-182. View abstract.

Chung, J. G., Chen, G. W., Hung, C. F., Lee, J. H., Ho, C. C., Ho, H. C., Chang, H. L., Lin, W. C., and Lin, J. G. Effects of berberine on arylamine N-acetyltransferase activity and 2-aminofluorene-DNA adduct formation in human leukemia cells. Am J Chin Med 2000;28(2):227-238. View abstract.

Chung, J. G., Wu, L. T., Chu, C. B., Jan, J. Y., Ho, C. C., Tsou, M. F., Lu, H. F., Chen, G. W., Lin, J. G., and Wang, T. F. Effects of berberine on arylamine N-acetyltransferase activity in human bladder tumour cells. Food Chem Toxicol 1999;37(4):319-326. View abstract.

Cometa MF, Abdel-Haq H, and Palmery M. Spasmolytic activities of Hydrastis canadensis L. on rat uterus and guinea-pig trachea. Phytotherapy Research 1998;12(suppl 1):S83-S85.

Desai, A. B., Shah, K. M., and Shah, D. M. Berberine in treatment of diarrhoea. Indian Pediatr. 1971;8(9):462-465. View abstract.

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Fukuda, K., Hibiya, Y., Mutoh, M., Koshiji, M., Akao, S., and Fujiwara, H. Inhibition by berberine of cyclooxygenase-2 transcriptional activity in human colon cancer cells. J Ethnopharmacol. 1999;66(2):227-233. View abstract.

Guo, Y., Chen, Y., Tan, Z. R., Klaassen, C. D., and Zhou, H. H. Repeated administration of berberine inhibits cytochromes P450 in humans. Eur J Clin Pharmacol 2012;68(2):213-217. View abstract.

Hajnicka, V., Kost’alova, D. , Svecova, D., Sochorova, R., Fuchsberger, N., and Toth, J. Effect of Mahonia aquifolium active compounds on interleukin-8 production in the human monocytic cell line THP-1. Planta Med 2002;68(3):266-268. View abstract.

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Hu, Y., Ehli, E. A., Kittelsrud, J., Ronan, P. J., Munger, K., Downey, T., Bohlen, K., Callahan, L., Munson, V., Jahnke, M., Marshall, L. L., Nelson, K., Huizenga, P., Hansen, R., Soundy, T. J., and Davies, G. E. Lipid-lowering effect of berberine in human subjects and rats. Phytomedicine. 7-15-2012;19(10):861-867. View abstract.

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Jeong, H. W., Hsu, K. C., Lee, J. W., Ham, M., Huh, J. Y., Shin, H. J., Kim, W. S., and Kim, J. B. Berberine suppresses proinflammatory responses through AMPK activation in macrophages. Am J Physiol Endocrinol.Metab 2009;296(4):E955-E964. View abstract.

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Kaneda Y, Tanaka T, and Saw T. Effects of berberine, a plant alkaloid, on the growth of anaerobic protozoa in axenic culture. Tokai J Exp Clin Med 1990;15(6):417-423.

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Khin, Maung U. and Nwe, Nwe Wai. Effect of berberine on enterotoxin-induced intestinal fluid accumulation in rats. J Diarrhoeal Dis Res 1992;10(4):201-204. View abstract.

Khin, Maung U., Myo, Khin, Nyunt, Nyunt Wai, Aye, Kyaw, and Tin, U. Clinical trial of berberine in acute watery diarrhoea. Br.Med.J.(Clin.Res.Ed) 12-7-1985;291(6509):1601-1605. View abstract.

Khin-Maung U, Myo-Khin, Nyunt-Nyunt-Wai, and et al. Clinical trial of high-dose berberine and tetracycline in cholera. J Diarrhoeal Dis Res 1987;5(3):184-187.

Kim, H. S., Kim, M. J., Kim, E. J., Yang, Y., Lee, M. S., and Lim, J. S. Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression. Biochem.Pharmacol 2-1-2012;83(3):385-394. View abstract.

Kim, W. S., Lee, Y. S., Cha, S. H., Jeong, H. W., Choe, S. S., Lee, M. R., Oh, G. T., Park, H. S., Lee, K. U., Lane, M. D., and Kim, J. B. Berberine improves lipid dysregulation in obesity by controlling central and peripheral AMPK activity. Am J Physiol Endocrinol.Metab 2009;296(4):E812-E819. View abstract.

Kong, W., Wei, J., Abidi, P., Lin, M., Inaba, S., Li, C., Wang, Y., Wang, Z., Si, S., Pan, H., Wang, S. , Wu, J., Wang, Y., Li, Z., Liu, J., and Jiang, J. D. Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. Nat Med 2004;10(12):1344-1351. View abstract.

Kowalewski, Z., Mrozikiewicz, A., Bobkiewicz, T., Drost, K., and Hladon, B. [Toxicity of berberine sulfate]. Acta Pol.Pharm 1975;32(1):113-120. View abstract.

Kulkarni, S. K., Dandiya, P. C., and Varandani, N. L. Pharmacological investigations of berberine sulphate. Jpn.J Pharmacol. 1972;22(1):11-16. View abstract.

Kuo, C. L., Chi, C. W., and Liu, T. Y. Modulation of apoptosis by berberine through inhibition of cyclooxygenase-2 and Mcl-1 expression in oral cancer cells. In Vivo 2005;19(1):247-252. View abstract.

Kuo, C. L., Chou, C. C., and Yung, B. Y. Berberine complexes with DNA in the berberine-induced apoptosis in human leukemic HL-60 cells. Cancer Lett 7-13-1995;93(2):193-200. View abstract.

Lahiri S and Dutta NK. Berberine and chloramphenicol in the treatment of cholera and severe diarrhoea. Journal of the Indian Medical Association 1967;48(1):1-11. View abstract.

Lau, C. W., Yao, X. Q., Chen, Z. Y., Ko, W. H., and Huang, Y. Cardiovascular actions of berberine. Cardiovasc Drug Rev 2001;19(3):234-244. View abstract.

Lee, S., Lim, H. J., Park, H. Y., Lee, K. S., Park, J. H., and Jang, Y. Berberine inhibits rat vascular smooth muscle cell proliferation and migration in vitro and improves neointima formation after balloon injury in vivo. Berberine improves neointima formation in a rat model. Atherosclerosis 2006;186(1):29-37. View abstract.

Lee, Y. S., Kim, W. S., Kim, K. H., Yoon, M. J., Cho, H. J., Shen, Y., Ye, J. M., Lee, C. H., Oh, W. K., Kim, C. T., Hohnen-Behrens, C., Gosby, A., Kraegen, E. W., James, D. E., and Kim, J. B. Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states. Diabetes 2006;55(8):2256-2264. View abstract.

Li XB. [Controlled clinical trial in infants and children comparing Lacteol Fort sachets with two antidiarrhoeal reference drugs]. Ann Pediatr 1995;42(6):396-401.

Li, H., Miyahara, T., Tezuka, Y., Namba, T., Suzuki, T., Dowaki, R., Watanabe, M., Nemoto, N., Tonami, S., Seto, H., and Kadota, S. The effect of kampo formulae on bone resorption in vitro and in vivo. II. Detailed study of berberine. Biol Pharm Bull 1999;22(4):391-396. View abstract.

Lin, C. C., Kao, S. T., Chen, G. W., Ho, H. C., and Chung, J. G. Apoptosis of human leukemia HL-60 cells and murine leukemia WEHI-3 cells induced by berberine through the activation of caspase-3. Anticancer Res 2006;26(1A):227-242. View abstract.

Lin, J. G., Chung, J. G., Wu, L. T., Chen, G. W., Chang, H. L., and Wang, T. F. Effects of berberine on arylamine N-acetyltransferase activity in human colon tumor cells. Am J Chin Med 1999;27(2):265-275. View abstract.

Lin, J. P., Yang, J. S., Lee, J. H., Hsieh, W. T., and Chung, J. G. Berberine induces cell cycle arrest and apoptosis in human gastric carcinoma SNU-5 cell line. World J Gastroenterol. 1-7-2006;12(1):21-28. View abstract.

Lin, S., Tsai, S. C., Lee, C. C., Wang, B. W., Liou, J. Y., and Shyu, K. G. Berberine inhibits HIF-1alpha expression via enhanced proteolysis. Mol Pharmacol 2004;66(3):612-619. View abstract.

Liu CX, Xiao PG, and Liu GS. Studies on plant resources, pharmacology and clinical treatment with berbamine. Phytotherapy Research 1991;5:228-230.

Lu, S. S., Yu, Y. L., Zhu, H. J., Liu, X. D., Liu, L., Liu, Y. W., Wang, P., Xie, L., and Wang, G. J. Berberine promotes glucagon-like peptide-1 (7-36) amide secretion in streptozotocin-induced diabetic rats. J Endocrinol. 2009;200(2):159-165. View abstract.

Mantena, S. K., Sharma, S. D., and Katiyar, S. K. Berberine, a natural product, induces G1-phase cell cycle arrest and caspase-3-dependent apoptosis in human prostate carcinoma cells. Mol Cancer Ther 2006;5(2):296-308. View abstract.

Marazzi, G., Cacciotti, L., Pelliccia, F., Iaia, L., Volterrani, M., Caminiti, G., Sposato, B., Massaro, R., Grieco, F. , and Rosano, G. Long-term effects of nutraceuticals (berberine, red yeast rice, policosanol) in elderly hypercholesterolemic patients. Adv.Ther 2011;28(12):1105-1113. View abstract.

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Meng, S., Wang, L. S., Huang, Z. Q., Zhou, Q., Sun, Y. G., Cao, J. T., Li, Y. G., and Wang, C. Q. Berberine ameliorates inflammation in patients with acute coronary syndrome following percutaneous coronary intervention. Clin Exp.Pharmacol Physiol 2012;39(5):406-411. View abstract.

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Nature’s Truth Echinacea & Goldenseal Root (250 ct.)

Enjoy an herbal support complex for year-round wellness with Nature’s Truth® Echinacea & Goldenseal Root!† These vegetarian capsules were made with your well-being in mind and deliver the dynamic herbal duo of Echinacea and Goldenseal Root to provide advanced support.†

Herbal Blend of Echinacea & Goldenseal

Each serving of Nature’s Truth® Echinacea & Goldenseal Root provides a 1,400mg Proprietary Herbal Blend** of these two traditional herbs. This blend features a 10:1 extract of Echinacea (Echinacea purpurea) and a 4:1 extract of Goldenseal (Hydrastis canadensis), making it a convenient way to add this traditional herbal supplement to your daily routine.†

Experience Echinacea

Echinacea has been used for hundreds of years in traditional herbal health practices. Today, it is still beloved for its many benefits. Native to the prairies and forests of North America, Echinacea is a flowering plant that’s part of the daisy family. It also goes by the name purple coneflower.

Goldenseal Goodness

Like Echinacea, Goldenseal Root has also been used for centuries for its beneficial wellness properties. Goldenseal is native to the dense forests of North America and is a perennial herb of the buttercup family. Goldenseal Root is also known as orangeroot or yellow puccoon.

What’s the Serving Size?

Take two Nature’s Truth® Echinacea & Goldenseal Root capsules one to two times a day, preferably with meals.

Experience the Power of Nature’s Truth®

Built on a foundation of truth, Nature’s Truth® uses only the best ingredients so you can enjoy an honestly clean wellness experience. Nature’s Truth vegetarian-friendly Echinacea & Goldenseal Root capsules supply the high-quality nutrition you deserve. They are Non-GMO, gluten-free, wheat-free, yeast-free, milk-free, lactose-free, soy-free, and free of artificial colors, artificial flavors, artificial sweeteners, and preservatives. Discover the Nature’s Truth® difference for yourself!

**Equivalent from a proprietary blend of Echinacea 10:1 extract and Goldenseal Root 4:1 extract per serving

90,000 benefits and harms to the body, echinacea resistance in oncology

Top 9 health benefits of echinacea – from colds to cancer

If you’ve ever looked for antiviral herbs to help fight colds and flu, chances are you’ve come across echinacea, a medicinal herb that is now very popular in the natural health market.

What is the reason for the popularity of this amazing flower? All thanks to its ability to maintain our health with the power of several types of various medicinal herbs.

Formerly known as an alternative way to prevent the common cold, echinacea quickly gained prominence for a range of benefits, from helping cancer treatments to relieving pain.

What else? For the prevention of diseases, you do not have to purchase preparations containing echinacea all year round. Instead, try making your own infusion and enjoy its amazing healing properties.

What is Echinacea?

Echinacea is a plant of the genus Rudbeckia, which came to us from North America.It was discovered by the indigenous people of the Great Plain over 400 years ago and has become a traditional healing remedy. As a medicinal plant, the flowers, leaves and roots of some types of echinacea are used to prepare medicines.

Until the 1950s and the advent of antibiotics, echinacea was very popular in medicine. But with the development of health care, antibiotics came to the fore, and the plant lost its status.

Now this flower can often be found in flower beds.Echinacea purpurea Echinacea purpurea with its purple-pink buds has become a favorite of gardeners and naturalists. Beautiful, chamomile-like flowers with pink, purple or violet petals and cone-shaped piths grow on sturdy stems high above the grass.

Many people do not even suspect how different the chemical compositions of the root system and the upper part of this plant are. If we analyze the roots of echinacea, we will see that they contain a high concentration of essential oils, and the aerial part of the plant contains a large amount of polysaccharides, which we know to support the immune system.Essentially, echinacea extract is an infusion from the top of it.

Most of the chemicals found in echinacea are powerful immunomodulators with important therapeutic functions. Among them are aromatic oils, vitamin C, inulin, flavonoids, and polysaccharides already known to us.

As mentioned above, the part of the plant that is above the ground is the most effective. So, in Germany, where food plants are under the control of the state, the stem and flowers Echinacea purpurea are considered a good natural remedy for combating infections of the urinary and upper respiratory tract, colds, as well as for accelerating the healing of various wounds and cuts.

Health Benefits

So what are the benefits of echinacea? Despite the fact that it has a lot of advantages, we presented 9 of the most striking ones.

Cancer Fight

An interesting study on the effects of echinacea on brain cancer has been published by the US National Institutes of Health. Scientists argue that “the medicinal value of the phytochemicals contained in echinacea is absolutely clear, that is, these agents, along with the phytochemicals of other medicinal herbs, can become a valuable aid in the fight against tumors.”

According to the study, the use of echinacea as an alternative cancer treatment can literally be recommended “in addition to or instead of conventional therapy.”

Strengthening the immune system

How does echinacea help fight colds and flu? In the journal Lancet Infectious Diseases , the University of Connecticut presented a meta-analytical study using data from 14 different papers that assesses the effect of echinacea.It showed that:

  • Echinacea May Reduce the Chance of Getting Cold by 58%
  • Echinacea reduces the duration of colds by 1-1.5 days

Craig Coleman, assistant professor of pharmaceutical practice and lead author of this study, added that “the main result of this work is that echinacea does have a powerful preventive and curative effect.” That is why preparations containing echinacea are one of the most effective anti-cold remedies.

Dr. Coleman noted that “the importance of such a discovery is clear given the fact that there are 1 billion cases of the common cold in the United States each year. Every year, Americans spend about $ 1.5 billion on doctor visits and another $ 2 billion on cough and cold medicine. ”

The US Natural Resources Conservation Service reports that the state of the immune system is highly dependent on the amount of echinacea extract taken. It turns out that a dose of 10 mg of this plant per 1 kg of body weight daily for 10 days can significantly strengthen your immunity.

Moreover, the medical journal “Hindawi” published material showing that echinacea protects against SARS. This plant is no less effective for frequent infections. To date, it has been proven to relieve cold symptoms, but echinacea may be more effective when cold symptoms are just beginning to appear.

Another study, this time published in the journal “Virus Research”, talks about the benefits of echinacea in the fight not only against SARS, but also against frequently occurring subsequent secondary bacterial infections.The plant extract is able to fight respiratory viral infections, including influenza, while reducing inflammation and reducing the risk of bacterial inflammation.

That is why preparations containing echinacea are often used to treat colds and flu, and its extract is recommended to their patients by homeopaths, naturopaths and therapists.

Pain Relief

Echinacea first showed itself when the Indians of the Great Plains began to use Echinacea purpurea as a pain reliever.This plant is especially effective for:

  • intestinal pain
  • headache
  • herpes-associated pain
  • measles
  • throat disease
  • 90,050 snakebites

  • abdominal pain angina
  • toothache

To relieve pain, it is enough to drink an infusion of echinacea or apply a paste of dried herb to the area of ​​pain.


Like most herbs, echinacea has a healing effect primarily on the stomach and gastrointestinal tract in general.In herbal medicine, for example, echinacea acts as a mild laxative for constipation with a calming effect.

In this case, it is enough to drink herbal tea. If the problem is regular, then a cup of infusion will help relax the intestines, and 2-3 cups a day will cope with discomfort and pain.

However, to avoid side effects, do not overuse echinacea. Limit yourself to 2 cups of infusion per day and, if necessary according to the instructions on the drug, take food supplements.

Anti-inflammatory effect

Perhaps the root of most diseases is inflammation. It can be caused by a variety of causes, including stress, lack of sleep, and toxins. Fortunately, according to the University of British Columbia, regular consumption of echinacea can significantly alleviate and even slow down the inflammatory process.

Echinacea preparations can also help with uveitis, an inflammation of the choroid in the eye.For rheumatoid arthritis, regular use of herbal tea can reduce system-wide inflammation.

Improving skin condition

Other benefits of echinacea include fighting wrinkles and skin dehydration. Research has shown that echinacea extract products improve overall skin health. What’s nice is that it has no side effects such as irritation.

Improving mental health

Echinacea angustifolia, or Echinacea angustifolia, is recommended for ADD / ADHD-related ailments.Both children and adults with these diseases are prone to various kinds of emotional disorders, especially to:

  • Anxiety
  • depression
  • social phobia

Again, moderation is key. The recommended maximum single dose is 20 mg, not more. An overdose can only increase anxiety.

Elimination of upper respiratory tract problems

Due to its immunomodulatory and anti-inflammatory effect, echinacea is able to fight diseases of the upper respiratory tract, such as:

  • acute sinusitis
  • influenza
  • asthma
  • cold
  • groats
  • diphtheria
  • inflammation
  • acute pharyngitis
  • tuberculosis
  • whooping cough

In clinical studies of patients with asthma, echinacea has acted as an analogue of classical synthetic drugs.For the treatment of asthma. Scientists write: “Recent studies have shown that the secretion of cytokines in the cells of the bronchial epithelium in asthma can be stopped by drugs containing echinacea.”

Namely, echinacea has good bronchodilator and anti-inflammatory effects. The authors of this work concluded that this fact “provides a scientific basis for the use of this medicinal herb as an accompanying therapy for allergic diseases of the upper respiratory tract such as asthma.”

In more severe cases, the concentration of echinacea in the infusion, for example, will not be enough.

Infection control

Echinacea is also an amazing remedy for many infections. One study found that taking echinacea in combination with a cream could reduce the incidence of vaginal infections by 16% compared to using cream alone. This herb is also effective against:

  • bloodstream infections
  • genital herpes
  • gum disease
  • malaria
  • syphilis
  • typhus
  • urinary tract infections
  • vaginal infections caused by fungus

Echinacea use

Prevention of colds

A 2018 review of 82 studies published in the medical journal Evidence-Based Complementary and Alternative Medicine concluded that 2.4 mg of echinacea extract daily for 4 months will protect you from or, if you do get sick, reduce it. duration and will save you from complications.

Removal of symptoms and reduction of duration of illness

In 2015, the Journal of the American Medical Association published a meta-analysis of research, which says that if you start using echinacea at the onset of the first symptoms, the duration and severity of colds can be reduced.

Prevention of influenza

A 2009 cell study tells us that some types of influenza, including swine and the potentially deadly bird flu, are unable to infect cultured human cells that have been exposed to echinacea extract.

Of course, laboratory results may not always be applicable in real life. However, these findings, coupled with human studies, convince us to experience the healing powers of echinacea, especially when the cold is in the air.

Alleviating influenza symptoms and shortening the period of illness

A 2015 European study found echinacea to be as effective as the antiviral drug Oseltamivir when it comes to relieving flu symptoms and preventing complications.However, it is worth noting that in this case, it is worth starting to take echinacea already at an early stage of the disease.

In addition, scientists have shown that echinacea can also help:

  • defeat cancer
  • improve immunity
  • relieve pain
  • get rid of constipation
  • relieve inflammation
  • improve skin condition
  • Maintain Mental Health
  • to cope with diseases of the upper respiratory tract

Risks and side effects

It should be remembered that when taking large amounts of echinacea, unwanted effects may appear.In some cases, large amounts of this herb extract can cause nausea or dizziness. Especially in people with different types of allergies, you should not use echinacea to treat seasonal allergies, for example.

When administered intramuscularly, echinacea can cause even more serious side effects, such as diarrhea, disorientation, dizziness, dry mouth, fever, headache, insomnia, muscle and joint pain, nausea, abdominal pain and vomiting.

The most important thing to remember in order to avoid unpleasant consequences is not to exceed the recommended dose indicated on the drug. And with regular use, you should take a break every few weeks.

Release form and dosage

Echinacea is available in many stores, including health food stores, pharmacies, and even supermarkets. It can be seen in the form of liquid infusions, dry picks, capsules, tablets, and tea.

Although it is not officially proven in which form it is most effective, the US National Institutes of Health is confident that regular use of echinacea is certainly beneficial for both immunity and health in general, which is why it is often taken for colds and flu.

Some sources state that echinacea is most beneficial when taken within 7-10 days of the first symptoms of the disease. It is also believed that liquid forms of echinacea are more effective due to the easier absorption.

In this case, it is worth giving preference to alcohol-free drugs for both adults and children.

And the last thing I would like to warn about. Always buy drugs and medicines from trusted manufacturers only. Questionable products may contain ingredients not listed in the composition, or in other quantities.

Final conclusions

  • There are many reasons to take echinacea. However, it is most effective in relieving symptoms and slowing the development of viral diseases of the upper respiratory tract, such as the flu and colds.
  • Scientists also believe that echinacea is useful in fighting cancer, strengthening immunity, relieving pain and inflammation, relieving constipation, healing skin, supporting mental health, etc.
  • You can easily grow your own echinacea in your garden and experience its healing properties.

You can leave a request for planned hospitalization on our website and we will contact you.

Echinacea Plus + Goldenseal (Cartel +)

Echinacea Plus + Goldenseal

Echinacea Plus

Natural supplement for immunostimulation and treatment of colds.

120 capsules

capsule: echinacea extract – 50 mg, golden root extract – 40 mg or echinacea extract – 90 mg, golden root extract – 10 mg; alcohol solution: echinacea extract (total in solution 6 thousand mg) – 60%, golden root extract (total in solution 4 thousand mg) – 40% or echinacea extract (total in solution 9 thousand mg) -90%, extract golden root (total in solution 1 thousand mg) – 10%.

Pharmacological action:

  • stimulates cellular, local and general immunity, increases antiviral protection;
  • reduces the permeability of cell membranes for viruses and bacteria;
  • provides a direct anti-inflammatory and antibacterial effect;
  • partially inhibits the development of tumor tissues.

Golden Root:

  • Binds and removes toxins, incl. food origin;
  • has an antibacterial effect;
  • lowers blood sugar by increasing insulin production;
  • increases blood clotting.

Clinical indications:
colds, runny nose, catarrh of the upper respiratory tract, flu; herpes;
skin diseases (including purulent ones), psoriasis; rheumatoid arthritis; allergic diseases; leukemia; foodborne diseases.

Echinacea is non-toxic and does not cause side effects.

Directions for use: children – 1-3 capsules per day or 12 drops – 3 times a day (drip into tea, juice), adults 2-6 capsules or 25 drops – 3 times a day, preferably with meals. The course of admission is up to 10 days, followed by a break of 5 days.
After a break, you can continue taking the drug, if necessary, with an increase in the dose.

Registered by the Ministry of Health R.F.
Registration certificate No. 002039.I.840.10.2000

Echinacea purpurea with Canadian yellow root 450mg

The study of the immunomodulatory properties of Echinacea during its intake made it possible to establish an increase in the total number of leukocytes in the blood due to an increase in granulocytes (by 34-89%). This effect is due to the stimulating effect of Echinacea on the function of bone marrow hematopoiesis. At the same time, an increase in the phagocytic activity of both leukocytes and reticuloendothelial cells of the liver is observed.
These data served as the basis for the use of Echinacea preparations for diseases associated, first of all, with a weakening of the functional state of the immune system caused by various etiological factors: chronic inflammatory diseases, exposure to ionizing radiation of ultraviolet rays, chemotherapy drugs, long-term antibiotic therapy.
Along with immunomodulatory properties, Echinacea preparations have a number of other valuable properties, which primarily include antibacterial, antiviral and fungicidal properties.
Echinacea inhibits the growth of streptococcus, staphylococcus, Escherichia coli, influenza and herpes viruses, has a pronounced interferon-inducing effect.
The aerial part of E. purpurea is rich in polysaccharides, and the roots contain a fairly high concentration of inulin. Inulin activates the immune system by increasing the movement of white blood cells to areas of infection, increasing the solubility of immune complexes, and destroying bacteria, viruses, and other microorganisms.
Echinacea polysaccharides enhance macrophage phagocytosis and stimulate macrophage production of several components important for the immune system.Polysaccharides. contained in Echinacea purpurea, cause increased proliferation of phagocytes in the spleen and bone marrow, as well as the migration of granulocytes to the peripheral blood in vivo. In vitro, microphages are stimulated to produce interleukin-1, interleukin-6 and antitumor factor alpha, which increases the number of reactive oxygen messengers and inhibits the growth of Candida albicans.
Echinazides are perhaps the most beneficial component of Echinacea.
Echinazides, like penicillin, can be just as effective in killing large numbers of viruses, bacteria, fungi and protozoa (six milligrams of Echinazide is equivalent to one penicillin module).
Echinazides have a protective effect against free radicals generated by the breakdown of type III collagen, allowing collagen to return to its natural state.
Alkylamides, found in the highest concentration in Echinacea roots, have mild anesthetic properties.
Echinacea contains biologically active substances, this is due to its immunomodulatory properties. Echinacea composition: polysaccharides, resins, essential oils, organic acids and phytosterols (also polyunsaturated fatty ones), saponins, glycosides, tannins, alkaloids.Polyenes are substances that kill some types of fungi. Phenolic acids have antiseptic properties. Echinacea rhizomes and roots contain glucose, inulin, resins, fatty and essential oils, betaine – a substance that helps prevent the development of stroke and heart attack. It also contains phenol carboxylic acids, which have diuretic properties and strengthen the immune system. Echinacea received its properties due to the content of a number of unique components in it: essential oils, resins, vitamins, antioxidants, organic acids.The plant is rich in iron, calcium, selenium, magnesium, potassium, sodium, manganese, vitamins A, C, E. All together, these substances activate the healing effect of each other, creating a kind of natural multifunctional medicinal complex. The very same treatment with echinacea implies the elimination of the root causes of ailments.
All parts of echinacea contain a large amount of minerals, also rare, often lacking in our diet – potassium, calcium, manganese, selenium, zinc, as well as silver, molybdenum, cobalt, chlorine, aluminum, magnesium, iron, nickel, barium, vanadium, beryllium.
Echinacea has antifungal, anti-inflammatory, anti-allergic, immunomodulatory, antiviral, anti-rheumatic effects.
Echinacea also works as an antibiotic. She treats angina, flu, hepatitis, arthritis, prostatitis, impotence, eczema, psoriasis, wounds, burns and even depression. In other words, echinacea has a very wide application and is truly an invaluable gift of nature to man. It is most effective at the very beginning of diseases – throwing all the body’s protective resources to fight them, this plant does not allow diseases to develop and take large-scale forms.
Echinacea is multifunctional. This miraculous plant heals and rejuvenates our body, strengthens the immune system and cures many diseases. Echinacea can be called a priceless gift of nature, a kind of magic wand that quickly restores strength, health and youth. She saves us from many troubles and makes us feel great all year round. This is a real queen of medicinal plants, an irreplaceable queen, omnipotent and eternal.
It has a bacteriostatic, fungicidal, virostatic and anti-inflammatory effect, inhibits the formation of hyaluronidase, enhances deicopoiesis, is a strong activator of macrophages, granulocytes and lymphocytes (especially T-lymphocytes), increasing the body’s defenses, immunity and thus belongs to herbal stimulants or modulators the immune system.It also gently stimulates the adrenal cortex, increasing the production of hormones that have a certain anti-allergic and anti-rheumatic effect.
Juice from fresh inflorescences accelerates blood coagulation, and when applied topically, accelerates wound healing.

It can be grown in private plots – Echinacea thrives on well-treated and moist soil in sunny places. The entire ground part of the plant and its rhizomes are used as a medicinal raw material.For drying, echinacea is harvested during the growing season. In autumn, winter and spring it is drunk like tea, a cup a day for the prevention of diseases and three cups a day at the onset of these diseases. To make tea, two teaspoons of the plant are poured with half a liter of boiling water and infused for forty minutes. In summer, salads can be prepared from finely chopped leaves of this plant, pouring them with vegetable oil and adding dill, parsley and vegetables.
Fresh juice of echinacea leaves is used to rejuvenate the skin of the face and cleanse it of age spots, freckles and warts.And the juice of fresh inflorescences promotes rapid wound healing and rapid blood clotting.
Echinacea is part of the herbal preparations used in the treatment of joint diseases, alcoholism, dysbiosis. There is also echinacea in tablets in pharmacies, intended for the treatment and prevention of colds, activating the body’s defenses, restoring the psychological and physical state in case of stress and chronic fatigue, and so on. The range of application of these drugs is very wide.However, when seeking help from Echinacea, you should remember that it has some contraindications and can cause side effects. So, echinacea is not recommended for allergy sufferers, pregnant women and nursing mothers, children under four years old, people with tuberculosis, AIDS and a number of other diseases. Therefore, before starting treatment with an extract, tincture or echinacea preparations, it is imperative to consult a doctor.

Echinacea is popular in many countries: Germany, France, USA, etc.In the Federal Republic of Germany, the drug echinacin was obtained for oral administration and in ampoules. The German physician Madaus (1938) recommended echinacea for angina, tonsillitis, chroniosepsis, parametritis and various inflammatory diseases of internal organs.
The first researcher and popularizer of echinacea in our country was Professor S. A. Tomilin, who considered it a powerful stimulant of the central nervous system, a biostimulator and a wonderful therapeutic agent, like ginseng.
Echinacea is one of the most commonly used herbs used for medicinal purposes by the North American Indians.tumors, syphilis, gangrene, typhoid, malaria, hemorrhoids. By the 1920s, Echinacea was one of the most popular medications. Echinacea was introduced to Europe in the 1930s, extensively researched in the 1950s, and is now being used extensively in medicine.
In West Germany, more than 250 pharmaceuticals are manufactured from Echinacea, including extracts, ointments and beverages.
In 1997, US $ 1 billion worth of Echinacea preparations were sold worldwide.Echinacea is very popular in the USA and Europe. It is ranked among the ten most used herbs in the world in terms of sales.
Echinacea extracts are effectively used in the treatment of chronic upper respiratory tract infections.
In a double-blind, placebo-controlled study, 108 people took liquid echinacin for 8 weeks. Compared to the placebo group, those who took echinacin had a shorter duration of illness and less severe symptoms. In 36% of those treated with Echinatsin, the infection did not subsequently recur.
Echinacea can be a useful adjunct in cancer treatment.With Echinacea, leukocyte levels can be adjusted during radiation or chemotherapy. Thus, a study with 55 participants undergoing radiation therapy showed that 85% of patients taking E. purpurea at this time maintained a stable leukocyte count, while the rest of the patients showed a constant decrease. In patients with carcinoma who consumed Echinacea, the number of CD4 + cells, natural killer cells, and activated killer cells of lymphokines increased.At the same time, the level of CD8 + cells decreased. (Z) -18-pentadecadine found in the roots of E. rigrigea has a direct anti-cancer effect.
E. rigrigea in combination with ginseng (Rapach ginseng) is used in the treatment of AIDS patients and patients with chronic fatigue syndrome.
The anti-inflammatory efficacy of Echinitsea in the treatment of rheumatoid arthritis has been proven (4 ml of svez / this plant juice is approximately equivalent in action to 1 mg of cortisone).
In one study, taking 20 drops of E.rigrigea 3 times a day reduced inflammation by 21.8%. Although this reduction is less than half that caused by cortisone or prednisone, there were no side effects during treatment that occur with steroid use.
The use of Echinacea causes a decrease in the level of lipid peroxidation and enhances antioxidant protection, which is lacking in patients taking non-steroidal drugs.
Biologically active food supplement “Echinacea” is recommended for use:
• In diseases associated with a weakening of the functional state of the immune system caused by chronic inflammatory diseases, exposure to ionizing radiation, ultraviolet rays, chemotherapy drugs, long-term antibiotic therapy.
• With diabetes mellitus, liver diseases.
• To neutralize in the body the negative effects of various chemical compounds of a toxic nature contained in the air and food (heavy metals, pesticides, insecticides, fungicides).
• For the prevention and in the complex therapy of diseases of the upper respiratory tract.
• With inflammatory diseases (rheumatism, polyarthritis, prostatitis, gynecological disorders).
• For various wound processes (trophic ulcers, osteomyelitis), microbial eczema.
• For infectious and septic diseases. The biologically active substances that make up Echinacea inhibit the growth and reproduction of streptococcus, staphylococcus, Escherichia coli, influenza viruses, herpes, stomatitis.
• Outwardly: with carbuncles, abscesses, infected wounds, burns of I-III degree (with burns, the analgesic effect of Echinacea is manifested) and severe bedsores.
• For prophylactic purposes at the first sign of a cold.

Hydrastis can be used for the following ailments:
Inflammatory processes in the intestines.
Problems with the bladder and gallbladder, as well as stomach ailments.
Laryngitis, bronchitis and other respiratory problems.
Renal failure and liver disease.
rash and skin lesions similar to it;
various inflammatory skin ailments.
In addition, products based on Canadian yellowroot help regulate menstrual cycles. Recent studies by scientists have also confirmed the beneficial effects of the plant in the treatment of hypoglycemia.
According to numerous reviews, excellent results with the use of funds based on hydrastis were achieved in inflammatory processes of the oral cavity, vagina, intestines and even the eyes. It is also noted that the plant copes well with allergic reactions and helps to improve the protective function of the body in case of immunodeficiency.

Echinacea Tablets – Forever

Forever Echinacea Supreme – Description

Echinacea. In European countries, echinacea as a medicine became known not so long ago, at the beginning of the 20th century. They brought it from North America, which is the birthplace of echinacea. For centuries, the indigenous population of this continent has used this plant for medicinal purposes, especially in the cold season for colds and for the treatment of other diseases. All parts of the plant, without exception, were used to create decoctions, which were consumed internally, made lotions with them and rinsed out the mouth.Modern scientists have discovered a number of useful properties of echinacea, where the most important of them should be its ability to significantly enhance immunity in a short time. Echinacea is capable of not only helping the body to cope with various viral and bacterial infections. It is used for various diseases, about which you can find out in detail here – Echinacea – application and indications.

Canadian Golden Root. Native to North America, this medicinal plant was prized by the Indians and used for a variety of health problems.It was used in the treatment of various neoplasms, both malignant and benign, for various infectious diseases and pneumonia. Goldenseal canadian effectively eliminated problems of the cardiovascular system, liver diseases and eye diseases. The strongest quality of this plant must be its ability to positively influence the mucous membranes of the body. Thanks to this ability, many problems of the gastrointestinal tract are solved, wounds and ulcers heal very quickly, and inflammatory processes are relieved.

Grape seed extract. Grape seeds are known to contain the most powerful antioxidant – Resveratrol. This antioxidant allows the body to largely protect the body from the negative effects of free radicals, which makes it possible not only to prevent early aging of the body, but also is the strongest protection against cancer and hypercholesterolemia. Grape seed extract strengthens the immune system, strengthens blood vessels, restores sleep and has a beneficial effect on the kidneys.

Forever Echinacea tablets are, first of all, a powerful protection of your immunity, along with which many problems of various organs and systems of the body are solved.

Package content: 60 tablets

Recommendations for use: take 1 tablet 2 times a day. The course of admission is 1 month, after which it is necessary to take a break for at least 2 weeks.

Production: USA


(2 tablets contain)

  • A mixture of Echinacea Purpurea and Echinacea angustifolia (root) – 500 mg
  • Canadian Golden Root – 300 mg
  • Grape Seed Extract – 100 mg
  • Cellulose
  • Stearic acid
  • Magnesium stearate
  • Croscarmellose sodium
  • Silicon dioxide
  • Hydroxypropyl methylcellulose

Register in the company’s online store and get a discount for all products 15 – 30%.

Based on scientific evidence. The numbers in brackets (1, 2, 3) are interactive links to peer-reviewed scientific articles. Prepared by specialists for informational purposes only. It should not be used as a guide for the treatment of disease, and it cannot replace professional medical advice, diagnosis, or treatment. In case of illness or any symptoms, you should not self-medicate and should always see a doctor.

Clinical Study Male Breast Cancer: alvespimycin hydrochloride, laboratory biomarker analysis, pharmacological study – Clinical Research Register


Intervention type:


Intervention name:

alvespimycin hydrochloride


Given IV

Arm Group label:

Treatment (alvespimycin hydrochloride)

Intervention type:


Intervention name:

laboratory analysis of biomarkers


Correlation studies

Arm Group label:

Treatment (alvespimycin hydrochloride)

Intervention type:


Intervention name:

pharmacological research


Correlation studies

Arm Group label:

Treatment (alvespimycin hydrochloride)

Another name:

pharmacological research



Inclusion criteria: – Histologically confirmed solid tumor, including but not limited to: – Prostate – Breast – Ovary – Colon – Kidney – Head and neck – Stomach – Melanoma – metastatic or inoperable disease – There is no standard curative or palliative therapy is no longer effective.- Progressive disease as indicated by the following: – Not prostate cancer – New lesions or enlargements of pre-existing ones on bone scintigraphy, CT scan, MRI, or physical examination – No increase in biochemical markers (such as carcinoembryonic antigen or CA-15-3) or symptoms as the only evidence of disease progression – Prostate cancer – Must have castrated metastatic disease (ie, disease progression after castration or treatment with a gonadotropin releasing hormone analogue [GnRH]) – Patients who have not had surgical orchiectomy should continue treatment.drug therapy (eg, GnRH analogs) to maintain serum testosterone castrate levels <50 ng / dL - Patients treated with antiandrogens as part of first-line hormones. therapy should show disease progression after stopping treatment - Progressive metastatic disease on imaging tests (eg, bone scans, computed tomography, or MRI) OR metastatic disease and an increase in prostate-specific antigen (PSA) levels are resolved - Biochemical progression is defined by at least 3 increases in PSA levels.3 - Bilirubin = <1.5 times the upper limit of normal (ULN) - AST and ALT <1.5 times the ULN - PT normal - Creatinine = <1.4 mg / dL - Creatinine clearance> 55 ml / min. – QTc <450 msec for male patients (470 msec for female patients) - LVEF> 40% MUGA – No history of serious ventricular arrhythmias (e.g., ventricular tachycardia or ventricular fibrillation> = 3 consecutive beats) – No myocardial infarction for the last year. – No active coronary artery disease in the past year – No New York Heart Association class III or IV congestive heart failure.- No congenital long QT syndrome – No left bundle branch block – No poorly controlled angina pectoris – No history of uncontrolled arrhythmias or the need for antiarrhythmic drugs. – Calcium blockers and beta-blockers are permitted – No other serious heart disease – Oxygen saturation> 88% – Dyspnea = Grade 2 – No mental illness or social situations that would interfere with adherence to the study regimen. – No other uncontrolled illness – More than 4 weeks since previous chemotherapy (6 weeks for mitomycin and nitrosourea) – At least 1 week since previous ketoconazole – More than 4 weeks since previous radiation therapy – Recovered from all previous therapy – More 4 weeks from the previous study of anticancer therapeutic drugs.- Lack of concurrent combination antiretroviral therapy for HIV-infected patients. – Do not take any of the following herbal medicines at the same time: – Hydrastis canadensis (yellow root) – Hypericum perforatum (St. John’s wort). St. John’s wort) – Uncaria tomentosa (cat’s claw) – Echinacea angustifolia roots – Trifolium pratense (wild cherry) – Matricaria chamomilla (chamomile) – Glycyrrhiza glabra (licorice) – Dillapiol – Hypericin – Naringenin – No other concurrent anti-tumor agents or treatments….



Minimum age:

18 years old

Maximum age:

N / A

Healthy volunteers:


Clinical study Unspecified solid tumor in adults, specific to the protocol: tanespimycin, irinotecan hydrochloride – Clinical trial registry

Inclusion criteria:

– Histologically confirmed solid tumor, excluding primary CNS tumors

– Localized disease standard therapy OR for which no standard therapy exists

– Tumor suitable for biopsy with Tru-cut®, CT or endoscopy (for patients, maximum tolerated dose treatment [extended cohort only])

– Pleural effusion or abdominal ascites not tissue considered available for biopsy

– There are no known new metastases in the central nervous system that have not been previously treated.3

– Bilirubin ≤ 1.5 mg / dL

– AST and ALT ≤ 3 times the upper limit of normal (ULN) (5 times the ULN if liver metastases are present)

– Creatinine ≤ 1.5 mg / dl

– No history of cardiac arrhythmias

– No myocardial infarction within the last 12 months

– No active coronary heart disease within the last 12 months

– No congestive heart failure class III-IV or LVEF <40% according to the classification of the New York Heart Association.MUGA

– No history of uncontrolled cardiac arrhythmia or dysrhythmia requiring medication

– No history of serious ventricular arrhythmias (eg, ventricular tachycardia or ventricular fibrillation ≥ 3 consecutive beats)

T No left bundle branch block

– QTc <450 msec (for male patients)

– QTc <470 msec (for female patients)

– Not pregnant

– Lack of nursing care during and during 2 months after participation in the study

– Negative pregnancy test

– Fertile patients should use effective contraception during the study and for 2 months afterwards.participation

– No serious or uncontrolled infections

– No serious allergic reactions to eggs or egg products.

– There are no other medical conditions that would prevent you from participating in the study.

– At least 3 weeks since the previous immunotherapy

– No concomitant administration of filgrastim (G-CSF) or sargramostim (GM-CSF).

– At least 3 weeks after previous chemotherapy (6 weeks for nitrosourea or mitomycin)

– Irinotecan pre-approved

– Without prior 17-N-allylamino-17-demethoxygeldanamycin (17-AAG)

– At least 2 weeks after previous nonmyelosuppressive chemotherapy (optional by Principal Investigator)

– At least 3 weeks after previous radiation therapy

– No previous radiation therapy field that would include the heart (e.g. mantle)

– Recovered from all previous therapy

– At least 3 weeks after previous studies of anticancer therapeutic drugs

– More than 7 days from the previous one and the absence of concurrent inducers, inhibitors or modifiers of CYP3A4, including any of the following:

– fluconazole

– Itraconazole

– Ketoconazole

– Azithromycin

– Clarithromycin

– Erythromycin

– Troleandomycin

– Nifedipine

– Verapamil

– Diltiazem

– Nefazodone

– Cyclosporine Juice ->

9000 Liters

– Cyclosporine Juice ->


– Ritonavir

– Saquinavir

– Carbamazepine

– Phenobarbital

– Phenytoin

– Rifampicin

– Hydrastis canadenum

– Hydrastis canadensis

– Hydmentrastis canadensis

– Echinacea angustifolia root

– Trifolium pratense (wild cherry)

– Matricaria chamomila (chamomile)

– Glycyrrhiza glabra (licorice)

– Dillapiol

– No concomitant

– Dillapiol

which would prolong QTc

– No concurrent vitamins, ant ioxidants, herbal preparations or supplements

– Concurrent use of multivitamins once a day is allowed

– No other concomitant anticancer therapy

– No concurrent antiretroviral combination therapy for HIV-infected patients.

– No other concurrent investigational drugs

by what means to remove papillomas

by what means to remove papillomas

by what means to remove papillomas


What means by what means to remove papillomas?

Papiderm is a unique medicine that has no analogues.This is due to the characteristics of the composition, which includes: Cordyceps extract; yellow root; shoots of potatoes; black walnut; maclura extract; extractor hood from shiitake.

The effect of using what means to remove papillomas

Papiderm contains only natural substances, so it has no contraindications and does not cause side effects. Ordered online, used a month in total. All the growths disappeared, as if they had never existed.I passed the tests again – there is no virus! Papiderm is really a very effective drug, and most importantly, absolutely safe. It would always be so quickly to get rid of all diseases …

Expert opinion

To enhance the effect, Papiderm can be taken orally. According to the instructions, the drops should be diluted in warm water (50 ml) and drunk in one gulp. The drug will fight the virus, helping the body to cope with the disease. It is important to understand that therapy is carried out in courses. The treatment time is selected individually.In most cases, 3-4 weeks are enough to remove skin defects.

How to order

In order to place an order by what means to remove papillomas, you must leave your contact information on the site. The operator will contact you within 15 minutes. Will clarify all the details with you and we will send your order. In 3-10 days you will receive the parcel and pay for it upon receipt.

Customer Reviews:


I have always had a lot of papillomas on my body.They did not give me much discomfort, so I never thought about treatment. After I turned 40, I noticed that there are more of them, and with great speed. I went to the hospital, where I was diagnosed with papillomavirus and prescribed a very expensive and voluminous treatment. I didn’t have enough money to buy all the drugs, so I decided to find some analogues. At the women’s forum I was advised by Papiderm. Real reviews of real people – regulars of the forum, became for me irrefutable proof of the effectiveness of the drug.I bought it on the official website, took it inside and processed the largest papillomas outside. Within a week, most of them were halved! And after another 2 weeks, even those that I had not processed disappeared. I am very pleased with the result, I recommend Papiderm to everyone!

Fyokla Pavlovna

Using Papiderm, you will permanently get rid of neoplasms, the virus in your body will be suppressed, and the immune system will be restored. The advantage over some drugs is that the body does not get used to it.Even after you stop using it, the virus will not show up again, as your immune system can already cope with the problem on its own.

Properties of the drug Papiderm: increases immunity; helps to suppress the activity of the virus in the body; reduces existing warts; prevents the appearance of new growths. The drug acts delicately, therefore it does not have an immediate effect. The end result can only be assessed after a full course of treatment.Where to buy by what means to remove papillomas? To enhance the effect, Papiderm can be taken orally. According to the instructions, the drops should be diluted in warm water (50 ml) and drunk in one gulp. The drug will fight the virus, helping the body to cope with the disease. It is important to understand that therapy is carried out in courses. The treatment time is selected individually. In most cases, 3-4 weeks are enough to remove skin defects.

List of the most effective drugs for papillomas Papillomas – skin formations that are caused by papillomaviruses of different types.Once in the body, the virus remains forever in the deep layers of the skin. Removing the file with special tools! Only a specialist will tell you how to bring out the pill in the home environment quickly. As a rule, this can be done using pharmaceuticals. It can be mazi, special solutions, and also tablets. The tablet form does not work. An effective remedy for papillomas is a drug that contains echinacea juice. This plant stimulates the production of immunity at the cellular level.Strong immunity is able to effectively fight the human papillomavirus, and. A place. Name. Characteristics in the rating. Top 10 best remedies for papillomas and warts. 1. Verrukacid. Better efficiency and safety. 2. DEZPAPILON. The widest spectrum of action. 3. Vartosine. Papilloma is a benign skin growth that should. This medicine for human papillomavirus stimulates the immune system and removes it from. Freezing pharmaceuticals for papillomas. In a clinical setting, liquid nitrogen has been successfully used to get rid of papillomas.There are several pharmacy drugs that help to quickly and permanently remove papillomas without negative consequences. Usually, external agents are used in the form of ointments and solutions. Papillomas are one of the few diseases that can be absolutely asymptomatic for a long time. However, with the appearance of at least one provoking factor, it will be possible to observe the appearance of ugly formations on the body. Kako. Top 10 medicines for papillomas and warts. This review concerns primarily the vulgar warts that cover the legs and arms of patients.Sometimes it is necessary to treat flat and senile warts, as well as condylomas. It is difficult to independently diagnose the type of neoplasm. Human papillomavirus is a viral infection that leads to neoplasms with a positive prognosis, which occurs suddenly and causes significant discomfort to its owner. The most effective drugs for papilloma, a review of antipapiloma drugs against viral formations on the body, skin of adults and children. Medicines for HPV removal that you can buy from.There are many remedies for papillomas, they are divided depending on the specific mechanism of action. … Review of medicines. Topical keratolytic medicines for papillomas.




https: // www.galika.com/userfiles/chem_vyvesti_papillomu_aptechnymi_sredstvami2903.xml


Papiderm contains only natural substances, so it has no contraindications and does not cause side effects. Ordered online, used a month in total. All the growths disappeared, as if they had never existed. I passed the tests again – there is no virus! Papiderm is really a very effective drug, and most importantly, absolutely safe.It would always be so quickly to get rid of all diseases …

what means to remove papillomas

Papiderm is a unique medicine that has no analogues. This is due to the characteristics of the composition, which includes: Cordyceps extract; yellow root; shoots of potatoes; black walnut; maclura extract; extractor hood from shiitake.

Surgical treatment of cervical warts. Surgical treatment is used if long-term conservative treatment has failed. Then there is no point in delaying, because complications of the disease are possible.Content. 1 Flat and genital warts of the cervix. 2 Opinion of doctors about the most effective methods of treating warts and papillomas. 3 Removal of genital warts on the cervix. 4 Be careful. Flat condyloma of the cervix is ​​formed due to the fact that the virus enters the cells of deeper layers. They are more dangerous than pointed ones, because they are likely to degenerate into a cancerous growth. If treatment is not started on time, warts grow, capturing an ever larger area. Treatment of cervical warts.Even isolated warts found on the cervix must be removed. The sooner this happens, the lower the likelihood of complications. There are several methods of removal Treatment of cervical warts. You should go to a good gynecologist and start treating the disease as soon as possible. … 1. It is best to remove warts on the cervix using radiosurgery. This will allow not only to remove the damaged ones. Condyloma of the cervix is ​​a viral pathology. It is most common in women of childbearing age.It is dangerous because it can lead to infertility and oncopathologies of the organs of the reproductive system. Warts are benign formations, they never turn into cancer. Likewise, they should not be treated to protect the sexual partner, since removing genital warts does not guarantee you will get rid of the HPV that caused them. There is no better treatment for genital warts. The best treatment. Many women develop neoplasms on the cervix called warts. These are small tumors that are a manifestation of the human papillomavirus.Until some time, they are not dangerous. Treatment of cervical warts. You should go to a good gynecologist and start treating the disease as soon as possible.