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Side effects of red rice: Red Yeast Rice | NCCIH

Red Yeast Rice | NCCIH

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What is red yeast rice?

Red yeast rice is produced by fermentation of a yeast on rice. The yeast is usually Monascus purpureus.

Depending on the yeast strain used and the conditions of fermentation, the yeast can enrich the rice with substances known as monacolins, including monacolin K. Monacolin K is structurally identical to the medicine lovastatin.

Lovastatin, like other statin drugs, helps slow the production of cholesterol in the body to decrease the amount of cholesterol that may build up on the walls of arteries and block blood flow to the heart, brain, and other parts of the body. Statin drugs are used together with diet, weight loss, and exercise to reduce the risk of heart attack and stroke.

Red yeast rice comes in the forms of food, traditional Chinese medicine, dietary supplements, and other products.

How much monacolin K is in red yeast rice?

Traditional red yeast rice may contain trace amounts of monacolin K (lovastatin).

Some commercial red yeast rice products contain very little or no detectable monacolin K. Other products, however, have been found to contain large amounts of monacolin K. Some researchers reported that commercial lovastatin is illegally added to some red yeast rice products.

It’s impossible for consumers to know the amount of monacolin K in red yeast rice products. Levels of monacolin K and lovastatin are not usually included on product labels. A 2017 review analyzed 28 brands of red yeast rice products from mainstream retailers in the United States, and none of the products included the quantity of monacolin K on the label. Monacolin K was not detected in two brands, and in the 26 brands that contained monacolin K, the quantity ranged more than 60-fold, from 0.09 to 5.48 mg per 1,200 mg of red yeast rice.

How does the U.S. Food and Drug Administration (FDA) regulate red yeast rice products?

According to the FDA, red yeast rice products that have enhanced or added lovastatin—which is structurally identical to monacolin K—cannot be marketed as a dietary supplement in the United States. This regulation is based on the FDA’s approval of lovastatin as a new drug before it was ever marketed as a food or dietary supplement.

On several occasions, the FDA sent warning letters to companies selling red yeast rice products that had enhanced or added lovastatin, telling the companies to correct their violations.

Are red yeast rice products effective?

Red yeast rice products that have considerable amounts of monacolin K may effectively lower blood cholesterol levels, blood glucose levels, and blood pressure. They may also reduce the risk of heart problems and death in people with metabolic syndrome. (Metabolic syndrome, also called insulin resistance syndrome, is a group of conditions that raise the risk of heart disease, diabetes, and stroke.) But, because of the levels of monacolin K, these products are considered by the FDA to be unapproved new drugs and are not sold legally in the United States.

Other red yeast rice products may contain very little monacolin K, and it’s unknown if these products are effective in reducing cholesterol levels or improving other areas of health. Some products have levels of monacolin K that are below the level known to lower cholesterol in clinical trials.

Are red yeast rice products safe?

A 2019 systematic review of clinical trials suggested that red yeast rice products with varying levels of monacolin K were safe. But that went against the opinion of the European Food Safety Authority (EFSA), published in 2018, which concluded that exposure to monacolin K from red yeast rice products could lead to severe side effects. The EFSA panel could not identify a guaranteed safe dietary level of monacolins from red yeast rice products.

What are possible side effects from red yeast rice products?

Red yeast rice products that contain significant amounts of monacolin K can have the same potential side effects as statin drugs, including muscle, kidney, and liver damage. They may also cause digestive problems (such as diarrhea, nausea, and stomach pain) and other reported side effects.

Red yeast rice products can have the same types of drug interactions as statin drugs and therefore may interfere with certain medicines or increase the chance for side effects.

Are there other safety concerns with red yeast rice products?

Yes. Some red yeast rice products contain a contaminant called citrinin, which is toxic and can damage the kidneys.

In a 2021 analysis of 37 red yeast rice products, only one had citrinin levels below the maximum level currently set by the European Union. Also, four products that were contaminated with citrinin were labeled as “citrinin-free.”

Are red yeast rice products safe during pregnancy?

There are no studies on the safety of red yeast rice products during pregnancy or while breastfeeding. Red yeast rice products are not recommended for those who are pregnant or lactating.

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Key References

  • Cohen PA, Avula B, Khan IA. Variability in strength of red yeast rice supplements purchased from mainstream retailers. European Journal of Preventive Cardiology. 2017;24(13):1431-1434.
  • Consumer Lab Product Reviews. Red Yeast Rice Supplements Review. Accessed at www.consumerlab.com/reviews/red-yeast-rice-supplements-review/red-yeast-rice on May 27, 2022.
  • European Food Safety Authority (EFSA) Panel on Food Additives and Nutrient Sources Added to Food (ANS), Younes M, Aggett P, et al.  Scientific opinion on the safety of monacolins in red yeast rice. EFSA Journal. 2018;16(8):e05368.
  • Fogacci F, Banach M, Mikhailidis DP, et al. Safety of red yeast rice supplementation: a systematic review and meta-analysis of randomized controlled trials. Pharmacological Research. 2019;143:1-16.
  • Food and Drug Administration. Warning Letter: Dr. Sam Robbins, Inc. dba HFL Solutions, LLC, MARCS-CMS 608729, August 28, 2020. Accessed at www.fda.gov/inspections-compliance-enforcement-and-criminal-investigations/warning-letters/dr-sam-robbins-inc-dba-hfl-solutions-llc-608729-08282020 on May 27, 2022.
  • Food and Drug Administration. Warning Letter: Ip-6 International Inc., FLA-14-10, April 23, 2014. Accessed at web.archive.org/web/20140526231131/http://www.fda.gov/iceci/enforcementactions/warningletters/2014/ucm396822.htm on May 27, 2022.
  • Righetti L, Dall’Asta C, Bruni R. Risk assessment of RYR food supplements: perception vs. reality. Frontiers in Nutrition. 2021;8:792529.
  • Song J, Luo J, Ma Z, et al. Quality and authenticity control of functional red yeast rice—a review. Molecules. 2019;24(10):1944.
  • Yuan R, Yuan Y, Wang L, et al. Red yeast rice preparations reduce mortality, major cardiovascular adverse events, and risk factors for metabolic syndrome: a systematic review and meta-analysis. Frontiers in Pharmacology. 2022;13:744928.

Other References

  • Chen C-H, Yang J-C, Uang Y-S, et al. Improved dissolution rate and oral bioavailability of lovastatin in red yeast rice products. International Journal of Pharmaceutics. 2013;444(1-2):18-24.
  • Gordon RY, Cooperman T, Obermeyer W, et al. Marked variability of monacolin levels in commercial red yeast rice products: buyer beware! Archives of Internal Medicine. 2010;170(19):1722-1727.
  • Marley E, Brown P, Leeman D, et al. Analysis of citrinin in cereals, red yeast rice dietary supplement, and animal feed by immunoaffinity column cleanup and LC with fluorescence detection. Journal of AOAC International. 2016;99(4):1025-1031.
  • National Heart, Lung, and Blood Institute. What Is Metabolic Syndrome? Accessed at www.nhlbi.nih.gov/health/metabolic-syndrome on May 31, 2022.
  • Raschi E, Girardi A, Poluzzi E, et al. Adverse events to food supplements containing red yeast rice: comparative analysis of FAERS and CAERS reporting systems. Drug Safety. 2018;41(8):745-752.
  • Russo R, Gallelli L, Cannataro R, et al. When nutraceuticals reinforce drugs side effects: a case report. Current Drug Safety. 2016;11(3):264-266.
  • Twarużek M, Ałtyn I, Kosicki R, et al. Dietary supplements based on red yeast rice—a source of citrinin? Toxins (Basel). 2021;13(7):497.

Acknowledgments

NCCIH thanks D. Craig Hopp, Ph.D., and David Shurtleff, Ph.D., NCCIH, for their review of the 2022 update of this publication.

 

This publication is not copyrighted and is in the public domain. Duplication is encouraged.

NCCIH has provided this material for your information. It is not intended to substitute for the medical expertise and advice of your health care provider(s). We encourage you to discuss any decisions about treatment or care with your health care provider. The mention of any product, service, or therapy is not an endorsement by NCCIH.

Last Updated: November 2022

Red yeast rice Information | Mount Sinai

Angkak; Beni-koji; Hong qu; Hung-chu; Monascus; Red koji; Red leaven; Red rice; Xue zhi kang; Zhitai





Red yeast rice, also called Went Yeast, has been used for centuries in China as both food and medicine. It is made by fermenting a type of yeast called Monascus purpureus over red rice. In Chinese medicine, red yeast rice is used to lower cholesterol, improve blood circulation, and improve digestion.

Red yeast rice contains chemicals that are similar to prescription statin medications. One of these, called monacolin K, has the same makeup as the drug lovastatin (Mevacor). Doctors prescribe statins to lower LDL (“bad”) cholesterol levels and help reduce the risk of heart disease.

Researchers are not sure if red yeast rice lowers cholesterol because of the statin-like chemical or because of other things in red yeast rice, such as unsaturated fatty acids, isoflavones, and phytosterols. But because many red yeast rice supplements did have monacolin, the Food and Drug Administration (FDA) considered them to be drugs. Manufacturers were supposed to remove any red yeast rice products with monacolin from the market. As a result, many of the red yeast rice products you can buy may not contain monacolin. Unfortunately, there is no way to tell whether a product contains moacolin because it is not listed on the label.











































Therapeutic Uses

Prevention

Several studies have shown that red yeast rice lowers LDL (“bad”) cholesterol levels. High cholesterol levels raise the risk of heart disease. Red yeast (Monascus purpureus) stops the action of an enzyme in the body that helps make cholesterol.

Red yeast rice contains substances known as monacolins. One of these, monacolin K, has the same chemical makeup as lovastatin (Mevacor), a prescription drug that lowers cholesterol. Some researchers think that is why red yeast rice lowers cholesterol. Others point out that the amount of monacolin in red yeast rice is less than you would find in the prescription drug. They think there may be other substances in red yeast rice that help lower cholesterol. More research is needed.

Treatment

Several studies suggest that red yeast rice reduces high cholesterol. However, most of the studies have used a formulation of red yeast rice, Cholestin, which is no longer available in the U.S. You can still buy Cholestin, but it no longer has any red yeast rice. The FDA requires any red yeast product that has monacolin to be taken off the market.

These studies support the claim that red yeast rice lowers cholesterol:

  • One study by UCLA School of Medicine involved 83 people with high cholesterol levels. Those who took red yeast rice over a 12 week period had lower levels of total cholesterol, LDL cholesterol, and triglycerides (fats in the blood) compared to those taking placebo. HDL (“good”) cholesterol levels did not change in either study group.
  • A study presented to the American Heart Association showed that red yeast rice lowered LDL cholesterol. In the study, 187 people had mild-to-moderately high levels of total cholesterol and LDL cholesterol. The study showed that taking red yeast rice reduced total cholesterol by more than 16%, LDL cholesterol by 21%, and triglycerides by 24%. HDL cholesterol also went up by 14%.
  • In another 8-week study of 446 people with high cholesterol, those who took red yeast rice had a drop in cholesterol levels compared to those who took placebo. Total cholesterol fell by 22. 7%, LDL by 31%, and triglycerides by 34% in the red yeast rice group. HDL cholesterol went up by 20% in the red yeast rice group as well.












Dietary Sources

Asia, and Chinese communities in North America, use red yeast rice in powdered form as a food coloring for fish, alcoholic beverages, and cheese.












Dosage and Administration

Red yeast rice is an ingredient in several supplements advertised to promote heart health. Red yeast rice is also available in commercial preparations. One of the proprietary products most often studied was Cholestin, which contained monacolin. However, that product is no longer on the market. The current ingredients in Cholestin do not include red yeast rice.

Pediatric

People younger than 20 should not use red yeast rice supplements.

Adult

In Traditional Chinese Medicine (TCM), the dosage of dietary or supplemental red yeast rice can be quite high. But the right dose for adults may be different, depending on the form of the supplement. Most studies have used standardized extract: 600 mg, 2 to 4 times daily.












Precautions

Researchers do not know whether it is safe to use red yeast rice for longer than 12 weeks.

People with liver disease, and those at risk for liver disease, should not take red yeast rice. Red yeast rice may affect the function in the same way prescription drugs to lower cholesterol can.

These people should not take red yeast rice: people with kidney disease, thyroid problems, or musculoskeletal disorders, or those at higher risk of cancer.

People who drink more than two alcoholic beverages a day, have a serious infection or physical condition, or have had an organ transplant should also avoid using red yeast rice.

Side Effects

Side effects of red yeast rice are rare but can include:

  • Headache
  • Stomachache or bloating
  • Gas
  • Dizziness
  • Heartburn
  • Muscle aches and weakness. This can lead to a rare but serious condition called rhabdomyolysis. Stop taking red yeast rice immediately and call your doctor

Pregnancy and Breastfeeding

Pregnant and breastfeeding women should not take red yeast rice.

Pediatric Use

People under 20 should not take red yeast rice until more research is done.

Geriatric Use

No studies have looked at the safety of red yeast rice in older adults. However, elderly people who took 1,200 mg per day of red yeast rice in an 8 week study had no major side effects.












Interactions and Depletions

Cholesterol-lowering medications: If you take drugs to lower your cholesterol, you should not take red yeast rice unless your doctor tells you to. Red yeast rice may make the effect of these drugs stronger, increasing the risk of liver damage. If you are already taking a statin or other drug to lower cholesterol, talk to your doctor before taking red yeast rice.

Anticoagulants (blood-thinners): Red yeast rice may increase the risk of bleeding. Blood thinners include warfarin (Coumadin), clopidogrel (Plavix), and daily aspirin.

Grapefruit juice: If you take a statin, grapefruit and grapefruit juice can increase the amount of the drug in your blood. That can give you a greater chance of side effects and liver damage. Because red yeast rice may act like statins in the body, you should not drink grapefruit juice or eat grapefruit while taking red yeast rice.

Coenzyme Q10 (CoQ10): Statins can lower the amount of CoQ10 in the body. CoQ10 is very important in heart and muscle health and in energy production. Not having enough CoQ10 can cause fatigue, muscle aches and pains, and muscle damage. Red yeast rice also may lower amounts of CoQ10 in the body. Ask your doctor if you need to take CoQ10 while you are taking red yeast rice products.

Other medications: Because it acts like a statin, red yeast rice may pose the same potential risk of liver damage that statins do, when combined with other prescription medications that also affect the liver. Some of these include:

  • Azathioprine (Imuran)
  • Cimetidine (Tagamet)
  • Clarithromycin (Biaxin)
  • Cyclosporine
  • Diclofenac (Voltaren)
  • Erythromycin
  • Gemfibrozil (Lopid)
  • Itraconazole (Sporanox)
  • Ketoconazole (Nizoral)
  • Methotrexate (Rheumatrex)
  • Rosiglitazone (Avandia)
  • Valproic acid












Supporting Research

Becker DJ, French B, Morris PB, Silvent E, Gordon RY. Phytosterols, red yeast rice, and lifestyle changes instead of statins; a randomized, double-blinded, placebo-controlled trial. Am Heart J. 2013;166(1):187-96.

Becker DJ, Gordon RY, Halbert SC, French B, Morris PB, Rader DJ. Red yeast rice for dyslipidemia in statin-intolerant patients: a randomized trial. Ann Intern Med. 2009;150(12):830-9.

Becker DJ, Gordon RY, Morris PB, Yorko J, Gordon YJ, Li M, Iqbal N. Simvastatin vs therapeutic lifestyle changes and supplements: randomized primary prevention trial. Mayo Clin Proc. 2008 Jul;83(7):758-64.

Bonovich, K, Colfer H, Davidson M, Dujovne C, Greenspan M, Karlberg R, et al. A Multi-Center, Self-Controlled Study of Cholestin In Subjects With Elevated Cholesterol. American Hear Association. 39th Annual Conference on Cardiovascular Disease Epidemiology and Prevention, Orlando, Fl. March 1999.

Havel R. Dietary supplement or drug? The case of cholestin. Am J Clin Nutr. 1999;69(2):175-176.

Heber D, Yip I, Ashley JM, Elashoff DA, Go VLW. Cholesterol-lowering effects of a proprietary Chinese red-yeast-rice dietary supplement. Am J Clin Nutr. 1999;69:231-236.

Huang CF, Li TC, Lin CC, Liu CS, Shih HC, Lai MM. Efficacy of Monascus purpureus Went rice on lowering lipid ratios in hypercholesterolemic patients. Eur J Cardiovasc Prev Rehabil. 2007 Jun;14(3):438-40.

Li C, Li Y, Hou Z. Toxicity study for Monascus purpureus (red yeast) extract. Information of the Chinese Pharmacology Society. 1995;12(4):12 [Translation].

Li C, Zhu Y, Wang Y, Zhu J, Chang J, Kritchevsky D. Monascus Purpureus-Fermented Rice (Red Yeast Rice): A natural food product that lowers blood cholesterol in animal models of hypercholesterolemia. Nutrition Research. 1998;18(1):71-81.

Li Y, Jiang L, Jia Z, et al. A meta-analysis of red yeast rice: an effective and relatively safe alternative approach for dyslipidemia. PLoS One. 2014;9(6):e98611.

Liu J, Zhang J, Shi Y, Grimsgaard S, Alraek T, Fønnebø V. Chinese red yeast rice (Monascus purpureus) for primary hyperlipidemia: a meta-analysis of randomized controlled trials. Chin Med. 2006 Nov 23;1:4.

Ma J, Li Y, Ye Q, Li J, Hua Y, Ju D, et al. Constituents of red yeast rice, a traditional Chinese food and medicine. J Agric Food Chem. 2000;48:5220-5225.

Mark D. All red yeast rice products are not created equal. The Am J of Cardiol. 106(3).

Mueller PS. Symptomatic myopathy due to red yeast rice. Ann Intern Med. 2006;145(6):474-5.

Ong HT, Cheah JS. Statin alternatives or just placebo: an objective review of omega-3, red yeast rice and garlic in cardiovascular therapeutics. Chin Med J (Engl). 2008 Aug 20;121(16):1588-94.

Qin S, Zhang W, Qi P, Zhao M, Dong Z, Li Y , et al. Elderly patients with primary hyperlipidemia benefited from treatment with a Monacus purpureus rice preparation: A placebo-controlled, double-blind clinical trial. American Heart Association. 39th Annual conference on Cardiovascular Disease Epidemiology and Prevention, Orlando, Fl. March 1999.

Shamim S, Al Badarin FJ, DiNicolantonio JJ, Lavie CJ, O’Keefe JH. Red yeast rice for dysipidemia. Mo Med. 2013;110(4):349-54.

Wang J, Lu Z, Chi J, Wang W, Su M, Kou W, et al. Multicenter clinical trial of serum lipid-lowering effects of a Monascus purpureus (red yeast) rice preparation from traditional Chinese medicine. Curr Ther Res. 1997;58(12):964-978.

Venero C, Venero J, Wortham D, Thompson P. Lipid-lowering efficacy of red yeast rice in a population intolerant to statins. The Am J Cardiol. 2010;105(5):664-6.

Vercelli L, Mongini T, Olivero N, Rodolico C, Musumeci O, Palmucci L. Chinese red rice depletes muscle coenzyme Q10 and maintains muscle damage after discontinuation of statin treatment. J Am Geriatr Soc. 2006;54(4):718-20.










RED YEAST RICE – PREVENTION FOR THE THREE MOST TERRIBLE DISEASES

I am a fan of natural or alternative medicine and therefore inspire others to use everything nature has given us to heal themselves. Raw Yeast Rice may not seem very attractive, but their active ingredients are very effective. It can be your number one healer if you are suffering from problems that red rice yeast can cure.

Red yeast rice is obtained by fermentation. It has been used in traditional Chinese medicine for centuries due to its powerful healing properties. What is interesting about this alternative medicine is that although it is rice yeast, it is suitable for people who are sensitive to fungal diseases. So, if you’ve had to fight a fungus, red rice yeast won’t do you much harm. You can use them when you are trying to get rid of a fungus or if you are hypersensitive to fungi.

Red rice yeast is primarily good for heart health, but it has other benefits as well. Find out what red rice yeast can do and see if it’s your alternative healer. My goal is to bring you all closer to nature and inspire you to take care of your health with the power of nature.

It contains natural monacolin K, the herb’s number one heart and circulatory protection.

Strong heart builder , protector of the cardiovascular system and cholesterol reducer .

Cardiovascular disease is at the forefront of the post-cancer world when it comes to diseases that take people out of this world. Therefore, it is extremely important for you and everyone else to take care of the health of your heart. These numbers are high because people get sick not only from stress and overwork, but also from food.

Red Yeast Rice helps protect your heart from disease and problems that can cause serious complications or put your life at risk.

This is a useful remedy for lowering cholesterol levels. If your cholesterol levels are too high, you can try red rice yeast instead of expensive drugs with side effects at your own risk. It is also used in Chinese traditional medicine to deal with such a problem.

Cholesterol levels can be high if you eat the wrong fats, such as animal fats ( meat, eggs, dairy products of animal origin ). Vegans rarely have cholesterol problems because they don’t consume animal fats.

Red Yeast Rice helps lower bad cholesterol levels, prolong heart life, and improve overall body health. Red yeast rice is known to have no side effects. Of course, all people perceive plants differently, and I emphasize that you all know for yourself what suits you and what does not.

Red Yeast Rice is the first plant I would personally turn to if my heart and circulatory system were in need of support.

This is a traditional Chinese medicine plant that reduces the risk of heart attack. If you have gone through this condition, then this may be an alternative medicine to prevent next time.

Possible prevention of chronic diseases: cancer, diabetes and heart disease.

Red yeast rice has a good property – it protects the body from inflammation. An inflamed body is a good playground for the most terrible diseases. Thanks to this, you can remove inflammation from your body and protect it from inflammation. In the same way help turmeric capsules, which also have anti-inflammatory effects.

Red Yeast Rice also helps to reduce the symptoms of chronic diseases and promote rehabilitation.

It can reduce the number of cancer cells and inhibit their growth. In fact, it is good to know what gives us all the chance to fight cancer if such a problem occurs in life. At the same time, you can take Red Yeast Rice Healing every year to prevent the development of serious diseases such as cancer. It’s worth considering if you feel that this alternative healer could be helpful for other issues as well, such as heart problems. In this case, you can give your body a two-in-one healing.

One of the best alternative drugs for the treatment of metabolic syndrome.

Metabolic syndrome is a serious disease that many people are not even aware of. Symptoms include obesity (even if you exercise and eat right), blood sugar fluctuations or high blood sugar, and high blood pressure.

Red Yeast Rice is an alternative herb that can be used to treat or support metabolic syndrome. It is also a potential assistant in preventive therapy.

Red Yeast Rice helps reduce blood diglycerides, making it easier to explain the fats in your blood. This, in turn, helps improve cardiovascular health and helps lower high blood pressure.

It is good for metabolism, helps to improve digestion and use of whole body fats. Thus, red yeast rice helps to prevent the weak side of the metabolic syndrome, that is, poor metabolism and the development of obesity.

Helps produce GABA. What is GABA and why is it important to know?

In short, GABA is an amino acid that your body makes. Red yeast rice contributes to its production. Many people around the world have problems with the production of GABA, which cause various mental problems, stress, depression, insomnia, nervousness, difficulty relaxing and feeling unwell. It is extremely important to eat in such a way that your body can produce GABA.

Red Yeast Rice contributes to the normal functioning of the body when the body needs to relax. GABA deficiency can be associated with many different mental problems that a person cannot resolve. For example, in addition to red rice, HAKA production is also supported by Bacopa Monnieri , Ashwagandha and Rhodiola .

Wearing Celectin or using this crystal also helps produce GABA. In addition, essential oil Clary sage should definitely be used in aromatherapy to produce GABA. What Else You Might Know About Red Yeast Rice … With the appearance of flatulence and pain in the abdomen, its use should be stopped immediately. Whatever new and unknown plants you use for your body, watch your feelings. Your feeling shows whether it suits you or not.

You can find more information on the application of HERE .

Red Yeast Rice is better absorbed by the body if you simultaneously consume omega-3 fatty acids .

You use the tips, tricks and information in this article at your own risk. The information provided represents Tené’s own experience, knowledge, personal opinion and recommendations. The use of red yeast rice is the responsibility of each individual. If necessary, consult your doctor before use.

RED YEAST RICE Alternative to synthetic statins.

What is
red yeast rice?

Red yeast rice (other names: RYR, vent rice, red fermented rice, red koji rice, akakoji, red koji rice, red koji rice, anka) is made by fermenting the yeast Monascus purpureus with rice. When rice is mixed with fermenting yeast, the resulting red yeast rice turns red-purple in color.
In Asia, powdered RYR is used to color a variety of foods including tofu, meat, fish, cheese, vinegar, baked goods, Korean rice wines, and Japanese sake.

CR contains the natural substance monacolin, which blocks the production of cholesterol. One of these monacolins found in RYR supplements is called monacolin K (lovastin) – this chemical is thought to be an active statin-like compound with the same chemistry as statins (cholesterol-lowering drugs) such as
lovastatin and mevinolin
.

Well, the most famous property of red rice is the ability to lower LDL cholesterol, known as “bad cholesterol”.
Many people with high cholesterol take red yeast rice supplements to avoid statins, which can be serious
side effects such as memory loss, liver damage, muscle pain, high blood sugar and even type 2 diabetes. Natural blends of statins in CR do not have these side effects.

✔️ A 2010 study examined the effects of red yeast rice supplementation on patients who
did not tolerate conventional statins
. Their total cholesterol decreased by 13%, LDL cholesterol decreased by 19%.
Another study assessed the effects of red rice on people with high cholesterol ages 23 to 65. The results showed
lower cholesterol
– 1.2 g per day lowered LDL levels by 26% in 8 weeks; 2.4g per day lowered LDL by 22% and total cholesterol by 16% in 12 weeks.

More Benefits:

✔️ Red Yeast Rice has been used in Traditional Chinese Medicine for over 1000 years to treat health problems associated with poor circulation and poor digestion.

✔️ Potential
in the treatment of obesity and hyperlipidemia.

✔️ One of the main complaints when taking statins is muscle fatigue. In fact, 10-15% of people taking statins experience skeletal muscle problems. Red yeast rice works just as well as statins, but
with less fatigue.

✔️ Reduction
biomarkers of oxidative stress.

✔️ Combination
Red Yeast Rice
+
Policosanol
+
Berberine (barberry)
renders
positive effect on insulin resistance
and other components of the metabolic syndrome. Course with berberine (as opposed to one red rice) 2 months 1 time in six months.

✔️ Red Rice Combination with nattokinase will help lower blood pressure, protect blood vessels from cholesterol plaques, improve blood flow and lipid profile.

✅ Take with food. It is advisable, not even mandatory, to take with Coenzyme Q10 (CoQ10) to prevent CoQ10 deficiency. These drugs, like statins, suppress the synthesis of coenzyme (due to natural statins), reducing it by 30-40%, and Ku10 is necessary for general health.


Jarrow Formulas, Red Yeast Rice + Coenzyme Q10

Dosage 1200 to 2400 mg 2 to 4 tablets of 600 mg. One study found that older people who took 1,200 mg (1.2 g) of RYR every day for 8 weeks had no serious side effects.
The effect is cumulative, it takes several months to see a significant reduction in cholesterol levels. You can take long courses and do not forget to monitor the tests. Consult your doctor!

❗️ Possible side effects and precautions

Red rice supplements should not be taken by people under 20 years of age.
Side effects are usually minor and may include headache, upset stomach, heartburn, gas, dizziness, muscle pain, and weakness—especially if the RYR supplement contains high levels of monacolin. If you experience muscle pain and weakness, discontinue use and consult a physician.

Avoid if you have kidney, liver, thyroid, musculoskeletal disease, or if there is an increased risk of cancer, if there is a serious infection.
It is recommended to avoid red yeast rice if you are taking any
of these medicines:

* Statins
* Serzon (antidepressant)
* Antifungals
* Drugs that suppress the immune system, such as cyclosporine
* Antibiotics erythromycin and clarithromycin (Biaxin)
*Protease inhibitors used to treat HIV

Do not eat grapefruit or take St. John’s wort with red rice or other statins.
Possible Interactions

If you have high cholesterol, it is also important to focus on diet and exercise. If you decide to try red yeast rice, make sure it’s from a trusted source. Do not buy cheap drugs from unknown manufacturers.

The amount of monacolins in RYR supplements may vary as manufacturers may use different yeast strains and fermentation processes.
Not all red yeast rice supplements contain the amount of lovastatins needed to lower high cholesterol.

FDA action:
In the late 1990s, the red yeast rice product Cholestin® was called into question because the label stated the amount of lovastatin and claimed the product’s ability to lower cholesterol. The FDA said that cholestin is an unapproved drug and ordered it to be taken off the market. However, other dietary supplements with red yeast rice continue to be sold in the US, but the labels only list the amount of red yeast rice, not the total amount or the amount of individual monacolins.
In August 2007, the FDA sent warning letters to several companies touting the cholesterol-lowering effects of their red yeast rice supplements. Products that did not claim to lower cholesterol or prevent disease received no warnings. That. any supplement containing lovastatin may violate FDA policy.

In short, you can’t sell supplements with monacolin on the label in the US, lovastatins make a lot of money, so like this ..

ConsumerLab tested red yeast rice supplements and their levels of lovastatin and citrinin (citrine is a potential toxin).
Tests show that the amount of lovastatin compounds in CR supplements varies widely.

There are no standards for the amount of lovastatin (monacolins K and KA) in red yeast rice supplements.