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Sulfacetamide Sodium Ophthalmic: Uses, Side Effects, and Essential Information

What is sulfacetamide sodium ophthalmic. How does it treat bacterial eye infections. What are the potential side effects and precautions. When should you consult a healthcare professional.

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Understanding Sulfacetamide Sodium Ophthalmic: A Comprehensive Guide

Sulfacetamide sodium ophthalmic is an antibiotic medication used to treat bacterial infections of the eyes. This powerful solution plays a crucial role in ophthalmology, offering relief to patients suffering from various eye conditions. Let’s delve into the details of this medication, exploring its uses, administration, and potential side effects.

What Is Sulfacetamide Sodium Ophthalmic and How Does It Work?

Sulfacetamide sodium ophthalmic is an antibiotic specifically formulated for use in the eyes. It belongs to a class of drugs known as sulfonamides, which work by inhibiting the growth and reproduction of bacteria. By targeting the bacterial cells responsible for eye infections, this medication helps to alleviate symptoms and promote healing.

Common Brand Names and Formulations

  • Bleph-10
  • Cetamide
  • Isopto Cetamide
  • Sodium Sulamyd
  • Sulf-10
  • AK-Sulf
  • Ocusulf-10

Sulfacetamide sodium ophthalmic is available in two primary formulations: ophthalmic ointment (10%) and ophthalmic solution (10%). The choice between these forms often depends on the specific condition being treated and the patient’s preferences.

Indications and Uses of Sulfacetamide Sodium Ophthalmic

The primary use of sulfacetamide sodium ophthalmic is to treat bacterial infections of the eyes. It’s important to note that this medication is only effective against bacterial infections and will not treat viral or fungal eye conditions. Some common eye infections that may be treated with sulfacetamide sodium ophthalmic include:

  • Conjunctivitis (pink eye)
  • Blepharitis (inflammation of the eyelids)
  • Keratitis (inflammation of the cornea)
  • Bacterial corneal ulcers

In some cases, healthcare providers may prescribe sulfacetamide sodium ophthalmic for off-label uses not listed in the medication guide. Always follow your doctor’s instructions and use the medication only as prescribed.

Proper Administration and Dosage Guidelines

Correct administration of sulfacetamide sodium ophthalmic is crucial for its effectiveness and safety. Here’s a step-by-step guide on how to use this medication:

  1. Wash your hands thoroughly before handling the medication.
  2. Tilt your head back and gently pull down your lower eyelid to create a small pocket.
  3. For eye drops: Hold the dropper above the eye and squeeze out the prescribed number of drops.
  4. For ointment: Squeeze a small ribbon of ointment into the lower eyelid pocket.
  5. Close your eyes for 2-3 minutes, tipping your head down without blinking.
  6. Gently press your finger to the inner corner of your eye for about a minute to prevent drainage.
  7. If using multiple eye medications, wait at least 10 minutes between applications.

It’s essential to avoid touching the tip of the dropper or ointment tube to prevent contamination. If you wear contact lenses, remove them before applying the medication and wait at least 15 minutes before reinserting them.

Potential Side Effects and Precautions

While sulfacetamide sodium ophthalmic is generally well-tolerated, it’s important to be aware of potential side effects and take necessary precautions. Some common side effects may include:

  • Temporary burning or stinging sensation
  • Blurred vision
  • Increased sensitivity to light
  • Mild eye irritation

In rare cases, more severe side effects may occur. Seek immediate medical attention if you experience:

  • Signs of an allergic reaction (hives, difficulty breathing, swelling of face, lips, tongue, or throat)
  • Severe eye pain or irritation
  • Vision changes
  • Signs of a new or worsening eye infection

Important Precautions

Before using sulfacetamide sodium ophthalmic, inform your healthcare provider about:

  • Any allergies, especially to sulfa drugs
  • Pregnancy or breastfeeding status
  • Other medications or eye drops you’re currently using

This medication should not be used in children younger than 2 months old without explicit medical advice.

Drug Interactions and Contraindications

While sulfacetamide sodium ophthalmic is generally safe, it’s important to be aware of potential drug interactions and contraindications. Some key points to consider include:

  • Avoid using other eye medications unless specifically instructed by your doctor
  • Inform your healthcare provider about all medications you’re taking, including over-the-counter drugs and supplements
  • Do not use sulfacetamide sodium ophthalmic if you have a known allergy to sulfa drugs

It’s crucial to provide your doctor with a complete medical history to ensure the safe and effective use of this medication.

Storage and Handling of Sulfacetamide Sodium Ophthalmic

Proper storage and handling of sulfacetamide sodium ophthalmic are essential for maintaining its effectiveness and safety. Follow these guidelines:

  • Store at room temperature away from moisture and heat
  • Do not freeze the medication
  • Keep the bottle or tube tightly closed when not in use
  • Do not use the medication if it has changed color or contains particles
  • Discard any unused medication after the expiration date

By following these storage instructions, you can help ensure that the medication remains potent and safe for use throughout its intended lifespan.

When to Seek Medical Attention

While sulfacetamide sodium ophthalmic is generally effective in treating bacterial eye infections, there are situations where you should seek immediate medical attention. Contact your healthcare provider if:

  • Your symptoms worsen or do not improve after a few days of treatment
  • You experience severe eye pain, vision changes, or signs of a new infection
  • You develop an allergic reaction to the medication
  • You accidentally ingest the medication

Remember, prompt medical attention can prevent complications and ensure proper treatment of your eye condition.

Monitoring Your Condition

During treatment with sulfacetamide sodium ophthalmic, it’s important to monitor your condition closely. Keep track of any changes in your symptoms and follow up with your healthcare provider as recommended. Regular check-ups can help ensure that the medication is working effectively and allow for any necessary adjustments to your treatment plan.

Frequently Asked Questions About Sulfacetamide Sodium Ophthalmic

To provide a comprehensive understanding of sulfacetamide sodium ophthalmic, let’s address some common questions patients often have about this medication:

Can I use sulfacetamide sodium ophthalmic while pregnant or breastfeeding?

The safety of sulfacetamide sodium ophthalmic during pregnancy and breastfeeding is not fully established. It’s crucial to consult your healthcare provider before using this medication if you are pregnant, planning to become pregnant, or breastfeeding. Your doctor will weigh the potential risks and benefits to determine if this treatment is appropriate for you.

How long does it take for sulfacetamide sodium ophthalmic to start working?

Many patients begin to experience relief from symptoms within a few days of starting treatment. However, it’s important to complete the full course of medication as prescribed by your doctor, even if your symptoms improve. Stopping the medication too soon may allow the infection to return or become resistant to treatment.

Can I wear contact lenses while using sulfacetamide sodium ophthalmic?

It’s generally recommended to avoid wearing contact lenses while using this medication. The preservatives in the solution can discolor soft contact lenses. If you must wear contacts, remove them before applying the medication and wait at least 15 minutes before reinserting them. Consult your eye care professional for specific guidance based on your individual situation.

What should I do if I miss a dose?

If you miss a dose of sulfacetamide sodium ophthalmic, apply it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra medication to make up for a missed dose, as this may increase the risk of side effects.

Can sulfacetamide sodium ophthalmic be used for viral eye infections?

No, sulfacetamide sodium ophthalmic is specifically designed to treat bacterial eye infections. It is not effective against viral or fungal infections. If you suspect you have a viral eye infection, such as viral conjunctivitis, consult your healthcare provider for appropriate treatment options.

Are there any lifestyle modifications I should make while using this medication?

While using sulfacetamide sodium ophthalmic, it’s advisable to:

  • Avoid rubbing your eyes
  • Refrain from wearing eye makeup until the infection clears
  • Use caution when driving or operating machinery, as the medication may cause temporary blurred vision
  • Avoid swimming or hot tubs until your doctor advises it’s safe to do so

These precautions can help prevent the spread of infection and promote faster healing.

Can I use over-the-counter eye drops along with sulfacetamide sodium ophthalmic?

It’s best to avoid using any other eye medications, including over-the-counter eye drops, unless specifically instructed by your healthcare provider. Some products may interfere with the effectiveness of sulfacetamide sodium ophthalmic or increase the risk of side effects. Always consult your doctor or pharmacist before combining eye medications.

How should I dispose of unused or expired sulfacetamide sodium ophthalmic?

Proper disposal of unused or expired medication is important for safety and environmental reasons. Do not flush the medication down the toilet or pour it down the drain. Instead, check with your local pharmacy about medication take-back programs or follow FDA guidelines for safe disposal of unused medicines.

The Role of Sulfacetamide Sodium Ophthalmic in Modern Ophthalmology

Sulfacetamide sodium ophthalmic plays a significant role in the treatment of bacterial eye infections in modern ophthalmology. Its effectiveness, combined with a generally favorable safety profile, makes it a valuable tool in the management of various ocular conditions. As research in ophthalmology continues to advance, we may see further refinements in the use of this medication and potentially new applications in eye care.

Ongoing Research and Future Perspectives

While sulfacetamide sodium ophthalmic has been a staple in ophthalmic care for many years, ongoing research continues to explore its potential benefits and limitations. Some areas of current interest include:

  • Combination therapies with other ophthalmic medications
  • Development of extended-release formulations for improved patient compliance
  • Investigation of its efficacy against emerging antibiotic-resistant bacterial strains
  • Exploration of potential new indications in ocular surface diseases

As our understanding of eye health and disease mechanisms grows, the role of sulfacetamide sodium ophthalmic may evolve, potentially leading to more targeted and effective treatment strategies in the future.

Patient Education and Empowerment in Eye Care

Understanding the proper use and potential effects of medications like sulfacetamide sodium ophthalmic is an essential part of patient education and empowerment in eye care. By being well-informed about their treatment, patients can:

  • Actively participate in their eye health management
  • Recognize and report potential side effects promptly
  • Adhere more closely to prescribed treatment regimens
  • Make informed decisions about their eye care in consultation with their healthcare providers

This knowledge not only improves treatment outcomes but also fosters a collaborative relationship between patients and their eye care professionals.

The Importance of Regular Eye Check-ups

While medications like sulfacetamide sodium ophthalmic are crucial in treating acute eye conditions, they are just one aspect of comprehensive eye care. Regular eye check-ups play a vital role in maintaining overall ocular health and can help detect potential issues before they become serious. During these check-ups, your eye care professional can:

  • Assess the effectiveness of ongoing treatments
  • Screen for early signs of eye diseases
  • Provide personalized advice on eye health maintenance
  • Update your prescription for corrective lenses if needed

By prioritizing both acute treatment with medications like sulfacetamide sodium ophthalmic and regular preventive care, patients can ensure the best possible outcomes for their long-term eye health.

Sulfacetamide ophthalmic Uses, Side Effects & Warnings

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Generic name: sulfacetamide ophthalmic [ SUL-fa-SEET-a-mide-off-THAL-mik ]
Brand names: Bleph-10, Cetamide, Isopto Cetamide, Sodium Sulamyd, Sulf-10,
… show all 12 brands
AK-Sulf, Ocusulf-10, Sulfac 10%, Sulfacet Sodium, Ocu-Sul 10, Ocu-Sul 15, Ocu-Sul 30

Dosage forms: ophthalmic ointment (10%), ophthalmic solution (10%)
Drug class: Ophthalmic anti-infectives

Medically reviewed by Drugs.com on May 1, 2023. Written by Cerner Multum.

What is sulfacetamide ophthalmic?

Sulfacetamide is an antibiotic.

Sulfacetamide ophthalmic (for use in the eyes) is used to treat bacterial infections of the eyes.

sulfacetamide ophthalmic will not treat a viral or fungal infection. Sulfacetamide ophthalmic is for use only in treating eye infections caused by bacteria.

Sulfacetamide ophthalmic may also be used for purposes not listed in this medication guide.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use sulfacetamide ophthalmic if you are allergic to sulfacetamide.

To make sure sulfacetamide ophthalmic is safe for you, tell your doctor if you have ever had an allergic reaction to a sulfa drug.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether sulfacetamide ophthalmic passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

Sulfacetamide ophthalmic should not be given to a child younger than 2 months old.

How should I use sulfacetamide ophthalmic?

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Do not use this medicine while wearing contact lenses. Sulfacetamide ophthalmic may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using this medicine before putting in your contact lenses.

Wash your hands before using eye medication.

To use this medicine:

  • Tilt your head back slightly and pull down your lower eyelid to create a small pocket.

  • Eye drops: Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop. Close your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct.

  • Use only the number of drops your doctor has prescribed. If you use more than one drop, wait about 5 minutes between drops.

  • Wait at least 10 minutes before using any other eye drops your doctor has prescribed.

  • Eye ointment: Hold the ointment tube with the tip pointing toward this pocket. Look up and away from the tip. Squeeze out a ribbon of ointment into the lower eyelid pocket without touching the tip of the tube to your eye. Blink your eye gently and then keep it closed for 1 or 2 minutes.

  • Use a tissue to wipe excess ointment from your eyelashes.

  • After opening your eyes, you may have blurred vision for a short time. Avoid driving or doing anything that requires you to be able to see clearly.

Do not touch the tip of the eye dropper or ointment tube. Do not place the tip directly on your eye. A contaminated dropper or tube can infect your eye, which could lead to serious vision problems.

Do not use the eye drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.

Store at room temperature away from moisture and heat. Do not freeze. Keep the bottle or tube tightly closed when not in use.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

An overdose of sulfacetamide ophthalmic is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

What should I avoid while using sulfacetamide ophthalmic?

sulfacetamide ophthalmic may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Do not use other eye medications unless your doctor tells you to.

Sulfacetamide ophthalmic side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your doctor right away if you have symptoms of a new or worsening eye infection: eye swelling, redness, severe discomfort, crusting or drainage.

Although the risk of serious side effects is low when sulfacetamide is used in the eyes, side effects can occur if the medicine is absorbed into your bloodstream. Stop using this medicine and call your doctor at once if you have:

  • confusion, feeling very irritable;

  • rapid weight gain, especially in your face and midsection;

  • easy bruising or bleeding;

  • pale skin, flu-like symptoms; or

  • severe skin reaction–fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common side effects may include mild eye redness or irritation, such as stinging or burning.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect sulfacetamide ophthalmic?

It is not likely that other drugs you take orally or inject will have an effect on sulfacetamide used in the eyes. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

More about sulfacetamide sodium ophthalmic

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  • Drug class: ophthalmic anti-infectives
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  • Patient Information
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Other brands

Bleph-10

Professional resources

  • Prescribing Information

Related treatment guides

  • Conjunctivitis
  • Eye Conditions
  • Trachoma

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Copyright 1996-2023 Cerner Multum, Inc. Version: 6.02.

Sulfacetamide Ophthalmic: MedlinePlus Drug Information


pronounced as (sul fa see’ ta mide)

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  • Why is this medication prescribed?
  • How should this medicine be used?
  • Other uses for this medicine
  • What special precautions should I follow?
  • What should I do if I forget a dose?
  • What side effects can this medication cause?
  • What should I know about storage and disposal of this medication?
  • What other information should I know?
  • Brand names
  • Brand names of combination products

Ophthalmic sulfacetamide stops the growth of bacteria that cause certain eye infections. It is used to treat eye infections and to prevent them after injuries.

Ophthalmic sulfacetamide comes as a solution (liquid) to instill in the eyes, and an ointment to apply to the eyes. The eye drops usually are instilled every 2 to 3 hours during the day and less frequently at night; the ointment usually is applied four times a day and at bedtime. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use sulfacetamide exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

To instill the eye drops, follow these steps:

  1. Wash your hands thoroughly with soap and water.
  2. Check the dropper tip to make sure that it is not chipped or cracked.
  3. Avoid touching the dropper tip against your eye or anything else; eye drops and droppers must be kept clean.
  4. While tilting your head back, pull down the lower lid of your eye with your index finger to form a pocket.
  5. Hold the dropper (tip down) with the other hand, as close to the eye as possible without touching it.
  6. Brace the remaining fingers of that hand against your face.
  7. While looking up, gently squeeze the dropper so that a single drop falls into the pocket made by the lower eyelid. Remove your index finger from the lower eyelid.
  8. Close your eye for 2 to 3 minutes and tip your head down as though looking at the floor. Try not to blink or squeeze your eyelids.
  9. Place a finger on the tear duct and apply gentle pressure.
  10. Wipe any excess liquid from your face with a tissue.
  11. If you are to use more than one drop in the same eye, wait at least 5 minutes before instilling the next drop.
  12. Replace and tighten the cap on the dropper bottle. Do not wipe or rinse the dropper tip.
  13. Wash your hands to remove any medication.

To apply the eye ointment, follow these instructions:

  1. Wash your hands thoroughly with soap and water.
  2. Avoid touching the tip of the tube against your eye or anything else; the tube tip must be kept clean.
  3. Holding the tube between your thumb and forefinger, place it as near to your eyelid as possible without touching it.
  4. Brace the remaining fingers of that hand against your face.
  5. Tilt your head backward slightly.
  6. With your index finger, pull the lower eyelid down to form a pocket.
  7. Squeeze a 1/4- to 1/2-inch (0.6- to 1.25-centimeter) ribbon of ointment into the pocket made by the lower eyelid. Remove your index finger from the lower eyelid.
  8. Blink your eye slowly; then gently close your eye for 1 to 2 minutes.
  9. With a tissue, wipe any excess ointment from the eyelids and lashes. With another clean tissue, wipe the tip of the tube clean.
  10. Replace and tighten the cap right away.
  11. Wash your hands to remove any medication.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Before using sulfacetamide eye drops or eye ointment,

  • tell your doctor and pharmacist if you are allergic to sulfacetamide, sulfa drugs, sulfites, or any other drugs.
  • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other eye medications and vitamins.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using sulfacetamide, call your doctor immediately.
  • you should know that your vision may be blurred during your treatment with sulfacetamide eye ointment. Avoid rubbing your eyes even if your vision is blurred. Do not drive a car or operate machinery if you are unable to see clearly.
  • tell your doctor if you wear soft contact lenses. If the brand of sulfacetamide you are using contains benzalkonium chloride, wait at least 15 minutes after using the medicine to put in soft contact lenses.

Instill or apply the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not instill or apply a double dose to make up for a missed one.

Sulfacetamide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • temporary stinging or burning of the eye
  • increased redness, itching, or swelling of the eye that continues for more than 48 hours

Keep this medication in the container it came in, tightly closed, and out of the reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Do not let it freeze and do not use discolored eye drops (yellowish brown to deep reddish brown).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA’s Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

  • AK-Sulf
  • Bleph-10®
  • Bleph-30®
  • Cetamide®
  • Sodium Sulamyd®
  • Blephamide® (containing Prednisolone, Sulfacetamide)
  • FML-S® (containing Fluorometholone, Sulfacetamide)
  • Vasocidin® (containing Prednisolone, Sulfacetamide)

This branded product is no longer on the market. Generic alternatives may be available.

Last Revised – 11/15/2015

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Sulfacetamide – description of the substance, pharmacology, use, contraindications, formula

Contents

  • Structural formula

  • Russian name

  • English name

  • Latin name

  • chemical name

  • Gross formula

  • Pharmacological group of the substance Sulfacetamide

  • Nosological classification

  • CAS code

  • pharmachologic effect

  • Characteristic

  • Pharmacology

  • Application of the substance Sulfacetamide

  • Contraindications

  • Application restrictions

  • Side effects of Sulfacetamide

  • Interaction

  • Dosage and administration

  • Precautionary measures

  • Trade names with the active substance Sulfacetamide

Structural formula

Russian name

Sulfacetamide

English name

Sulfacetamide

Latin name

Sulfacetamidum ( born Sulfacetamidi)

Chemical name

N-[(4-Aminophenyl)sulfonyl]acetamide

General formula

C 8 H 10 N 900 69 2 O 3 S

Pharmacological group of the substance Sulfacetamide

Sulfonamides

Ophthalmic products

Nosological classification

List of ICD-10 codes

CAS code

144-80-9

Pharmacological action

Pharmacological action

antibacterial , bacteriostatic , antimicrobial .

Characteristics

Sodium Sulfacetamide is an odorless white crystalline powder with a slightly bitter taste. Easily soluble in water, practically insoluble in ethanol, ether, acetone, chloroform.

Pharmacology

Competes with para-aminobenzoic acid in the synthesis of folate, reduces the formation of dihydrofolic acid, stops the growth and reproduction of microorganisms. The spectrum of action includes gram-positive and gram-negative microorganisms: Escherichia coli, Shigella spp., Vibrio cholerae, Clostridium perfringens, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp., Actinomyces israelii, Toxoplasma gondii .

When using ophthalmic forms, it penetrates into the tissues and fluids of the eye, is absorbed into the systemic circulation through the inflamed conjunctiva.

Use of the substance Sulfacetamide

Eye drops and ointment for external use: conjunctivitis, blepharitis, purulent corneal ulcer, prevention and treatment of blenorrhea in newborns, gonorrhea and chlamydial eye diseases in adults. Injection solution: pneumonia, purulent tracheobronchitis, urinary tract infections.

Contraindications

History of hypersensitivity, toxic-allergic reactions to sulfonamides.

Restrictions on use

In / in the introduction is contraindicated in severe diseases of the hematopoietic system and uremia.

Substance side effects Sulfacetamide

Severe hypersensitivity reactions to sulfa drugs (Stevens-Johnson syndrome, fever, skin rash, gastrointestinal disorders, bone marrow depression).

Local reactions: burning, lacrimation, pain, itching in the eyes, allergic reactions.

Interaction

Sulfacetamide is incompatible with silver salts. Combined use with procaine and tetracaine reduces the bacteriostatic effect.

Dosage and administration

Topically, parenterally . Locally: eye drops are instilled 1-2 drops into each conjunctival sac 4-6 times a day. For the prevention of blennorrhea in newborns – 2 drops in each conjunctival sac immediately after birth and 2 drops – after 2 hours. The ointment is applied over the eyelid 3-4 times a day.

IV slowly (over at least 5 minutes) 3-5 ml of a 30% solution twice a day with an interval of 12 hours.

Precautions

Patients with hypersensitivity to furosemide, thiazide diuretics, sulfonylurea or carbonic anhydrase inhibitors may be hypersensitive to sulfacetamide.

Trade names with active substance Sulfacetamide

Information for healthcare professionals only.
Are you a healthcare professional?

Sulfacyl sodium instructions for use: indications, contraindications, side effects – description Sulfacyl sodium eye drops 20%: vial-drip. 5 ml or 10 ml (10616)

💊 Composition of the preparation Sulfacyl sodium

✅ Application of the preparation Sulfacyl sodium

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Description of the active ingredients of the preparation

Sulfacyl sodium
(Sulfacyl sodium)

The scientific information provided is general and cannot be used to make decisions.
decisions about the use of a particular drug.

Update date: 2020.10.19

Marketing authorization holder:

RENEWAL OF PFK JSC
(Russia)

ATX code:

S01AB04

(Sulfacetamide)

Active substance:
sulfacetamide
(sulfacetamide)

Rec.INN

registered by WHO

Dosage form

Sulfacyl sodium

Eye drops 20%: vial-drop 5 ml or 10 ml

reg. No.: LS-001909
dated 24. 08.11
– Indefinitely

Release form, packaging and composition
drug Sulfacyl sodium

Eye drops 20% transparent, colorless or slightly colored.

5 ml – polymeric dropper bottles (1) – packs of cardboard.
10 ml – polymeric dropper bottles (1) – packs of cardboard.

Clinical and pharmacological group:

Drug with antimicrobial action for local use in ophthalmology

Pharmacotherapeutic group:

Antimicrobial agent, sulfanilamide

Pharmacological action

Antibacterial agent for topical use in ophthalmology, a derivative of sulfanilamide. It has a wide spectrum of antimicrobial activity. It has a bacteriostatic effect. The mechanism of action is associated with competitive antagonism with PABA and competitive inhibition of dihydropteroate synthetase, which leads to disruption of the synthesis of tetrahydrofolic acid, which is necessary for the synthesis of purines and pyrimidines.

Sulfacetamide is active against Gram-positive and Gram-negative cocci, Escherichia coli, Shigella spp., Vibrio cholerae, Clostridium perfringers, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp., Actinomyces israelii, Toxoplasma gondii.

Possible development of resistance to sulfacetamide.

Pharmacokinetics

When applied topically, it penetrates into the tissues and fluids of the eye. It is absorbed into the systemic circulation through the inflamed conjunctiva.

Sulfacetamide is metabolized in the liver by N-acetylation, metabolites have antibacterial activity.

Excretion of sulfacetamide occurs in the kidneys by glomerular filtration.

Indications of the active substances of the drug

Sulfacyl sodium

In the complex therapy of diseases of the eyelids, conjunctiva, cornea, anterior segment of the choroid and lacrimal ducts caused by microorganisms sensitive to sulfacetamide. Prevention of infectious complications in the complex therapy of burns and injuries of the organs of vision. Prevention of blennorrhea in newborns.

Open list of ICD-10 codes

A54.3 Gonococcal eye infection
H01.0 Blepharitis
H04.3 Acute and unspecified inflammation of lacrimal ducts
H04.4 Chronic inflammation of the lacrimal ducts
h20.2 Other acute conjunctivitis
h20.4 Chronic conjunctivitis
h20.5 Blepharoconjunctivitis
h26 Keratitis
h30. 0 Acute and subacute iridocyclitis (anterior uveitis)
h30.1 Chronic iridocyclitis
P39.1 Conjunctivitis and dacryocystitis in the newborn
S05 Trauma to the eye and orbit
T26 Thermal and chemical burns limited to the area of ​​the eye and adnexa
Z29.2 Other prophylactic chemotherapy (prophylactic administration of antibiotics)

Dosing regimen

The method of administration and dosing regimen of a particular drug depends on its form of release and other factors. The optimal dosage regimen is determined by the doctor. Compliance of the dosage form of a particular drug with indications for use and dosing regimen should be strictly observed.

Apply 2-3 drops into the lower conjunctival sac of each eye 5-6 times a day.

To prevent blennorrhea in newborns, 2 drops of solution are instilled into the eyes immediately after birth and 2 drops every 2 hours.

Side effects

Possible: physical conjunctivitis, the development of superinfection, severe allergic reactions to sulfonamides (Stevens-Johnson syndrome, toxic epidermolysis, fulminant liver necrosis, agranulocytosis, aplastic anemia).

Contraindications for use

Hypersensitivity to sulfacetamide and other sulfa drugs; children’s age up to 2 months – depending on the dosage form.

Use during pregnancy and lactation

During pregnancy and lactation, use only after consulting a doctor, in cases where the expected benefit to the mother outweighs the potential risk to the fetus or infant.

Pediatric use

May be used in children according to indications, in recommended doses and dosage forms according to age. It is necessary to strictly follow the instructions in the instructions for sulfacetamide preparations on contraindications for use in children of different ages of specific dosage forms of sulfacetamide.

Special instructions

Patients with hypersensitivity to furosemide, thiazide diuretics, sulfonylurea or carbonic anhydrase inhibitors may be hypersensitive to sulfacetamide.

Possible overgrowth of sulfanilamide-insensitive microorganisms and fungal flora.

A decrease in the antibacterial activity of sulfonamides is noted in the presence of high concentrations of para-aminobenzoic acid in the presence of a large amount of purulent discharge.

It is necessary to stop therapy in case of allergy symptoms, as well as intensification of pain and other signs of an infectious process, an increase in purulent discharge.

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