Toradol and Alcohol: Interactions, Side Effects, and Precautions
How does Toradol interact with alcohol. What are the potential side effects of combining Toradol and alcohol. Why should you avoid drinking alcohol while taking Toradol. What precautions should be taken when using Toradol.
Understanding Toradol: Uses and Mechanism of Action
Toradol, also known by its generic name ketorolac, is a potent nonsteroidal anti-inflammatory drug (NSAID) used for short-term management of moderate to severe pain. It works by reducing the production of prostaglandins, substances in the body that cause inflammation, pain, and fever.
How does Toradol differ from other pain medications. Toradol is unique among NSAIDs due to its powerful analgesic properties, often compared to opioids in terms of pain relief. However, it is not a narcotic and does not carry the same risks of addiction or respiratory depression associated with opioid medications.
Common Uses of Toradol
- Post-operative pain management
- Acute pain from kidney stones
- Migraine headaches
- Severe back pain
- Dental pain
Is Toradol suitable for long-term use. No, Toradol is typically prescribed for short-term use only, usually no longer than 5 days for oral formulations and 2 days for injectable forms. Prolonged use increases the risk of serious side effects.
The Dangers of Mixing Toradol and Alcohol
Combining Toradol with alcohol can significantly increase the risk of adverse effects, particularly gastrointestinal bleeding and ulceration. Both substances can irritate the stomach lining and interfere with the body’s natural protective mechanisms.
Why is the combination of Toradol and alcohol particularly risky. Alcohol enhances the blood-thinning properties of Toradol, which can lead to prolonged bleeding times and increase the likelihood of gastrointestinal hemorrhage. Additionally, both substances can cause liver stress, potentially leading to liver damage when used together.
Symptoms of Gastrointestinal Bleeding
- Black, tarry stools
- Blood in vomit or vomit that resembles coffee grounds
- Severe abdominal pain
- Dizziness or fainting
- Rapid heartbeat
How quickly can gastrointestinal bleeding occur when mixing Toradol and alcohol. The onset of gastrointestinal bleeding can be rapid and unpredictable. Some individuals may experience symptoms within hours of combining the two substances, while others may develop complications over a period of days or weeks.
Side Effects and Precautions When Using Toradol
Even when used as directed, Toradol can cause a range of side effects. It’s crucial to be aware of these potential reactions and take necessary precautions to minimize risks.
Common Side Effects of Toradol
- Stomach pain or discomfort
- Nausea and vomiting
- Headache
- Dizziness
- Drowsiness
Can Toradol cause allergic reactions. Yes, some individuals may experience allergic reactions to Toradol, which can range from mild skin rashes to severe anaphylaxis. It’s important to seek immediate medical attention if you experience symptoms such as difficulty breathing, swelling of the face or throat, or severe skin reactions.
Precautions When Taking Toradol
- Inform your healthcare provider about all medications you’re taking
- Avoid using Toradol if you have a history of stomach ulcers or bleeding disorders
- Use caution if you have kidney problems or are at risk for kidney disease
- Do not use Toradol before or after heart bypass surgery
- Avoid using Toradol during the last trimester of pregnancy
How does Toradol affect blood pressure. Toradol, like other NSAIDs, can cause fluid retention and increase blood pressure. Patients with hypertension or heart conditions should monitor their blood pressure closely while using this medication and consult their healthcare provider if they notice any significant changes.
Interactions Between Toradol and Other Medications
Toradol can interact with numerous medications, potentially altering their effectiveness or increasing the risk of side effects. It’s crucial to inform your healthcare provider about all medications, supplements, and herbal products you’re using.
Medications That May Interact with Toradol
- Other NSAIDs (e.g., ibuprofen, naproxen)
- Blood thinners (e.g., warfarin, heparin)
- Selective serotonin reuptake inhibitors (SSRIs)
- ACE inhibitors and ARBs
- Diuretics
- Methotrexate
- Lithium
Why is it important to avoid combining Toradol with other NSAIDs. Using multiple NSAIDs simultaneously can significantly increase the risk of gastrointestinal bleeding and ulceration. Additionally, it doesn’t provide any additional pain relief benefits and may lead to NSAID toxicity.
Proper Dosage and Administration of Toradol
The correct dosage of Toradol varies depending on the form of administration (oral, intramuscular, or intravenous) and the specific medical condition being treated. It’s crucial to follow your healthcare provider’s instructions carefully.
General Dosage Guidelines
- Oral tablets: Typically 10 mg every 4 to 6 hours, not to exceed 40 mg per day
- Intramuscular injection: Usually 30 to 60 mg as a single dose
- Intravenous administration: Generally 30 mg as a single dose
How long can Toradol be safely used. The duration of Toradol treatment should be limited to 5 days or less for oral formulations and 2 days or less for parenteral forms. Prolonged use increases the risk of serious side effects, particularly gastrointestinal and cardiovascular complications.
Alternatives to Toradol for Pain Management
For individuals who cannot take Toradol due to contraindications or those seeking alternatives, several other pain management options are available. The choice of alternative depends on the type and severity of pain, as well as individual patient factors.
Non-NSAID Pain Management Options
- Acetaminophen (Tylenol)
- Topical analgesics (e.g., lidocaine patches)
- Gabapentinoids (e.g., gabapentin, pregabalin)
- Tricyclic antidepressants
- Physical therapy and exercise
- Acupuncture
- Cognitive-behavioral therapy
Are there natural alternatives to Toradol for pain relief. Yes, some individuals find relief from pain using natural remedies such as turmeric, ginger, omega-3 fatty acids, or white willow bark. However, it’s important to note that these alternatives may not be as potent as Toradol and should be used under the guidance of a healthcare professional, especially if you have underlying health conditions or are taking other medications.
Long-term Effects of Toradol Use
While Toradol is intended for short-term use, some individuals may be prescribed this medication repeatedly over time. Understanding the potential long-term effects is crucial for patients and healthcare providers alike.
Potential Long-term Consequences of Toradol Use
- Increased risk of cardiovascular events (e.g., heart attack, stroke)
- Chronic kidney disease
- Gastrointestinal ulceration and bleeding
- Liver dysfunction
- Increased risk of bleeding disorders
How does long-term Toradol use affect the cardiovascular system. Prolonged use of Toradol and other NSAIDs can increase the risk of cardiovascular events by affecting blood clotting mechanisms and potentially raising blood pressure. This risk is particularly significant for individuals with pre-existing heart conditions or risk factors for heart disease.
Special Considerations for Toradol Use in Specific Populations
Certain groups of people may be at higher risk for complications when using Toradol. Healthcare providers must carefully consider these factors when prescribing the medication.
High-Risk Groups for Toradol Use
- Elderly patients
- Individuals with a history of gastrointestinal bleeding or ulcers
- Patients with kidney disease
- Those with liver impairment
- Pregnant women, especially in the third trimester
- Individuals with bleeding disorders
- Patients with cardiovascular disease
Why is Toradol use particularly risky in elderly patients. Older adults are more susceptible to the side effects of NSAIDs, including Toradol. They have a higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Additionally, elderly patients often take multiple medications, increasing the likelihood of drug interactions.
Can Toradol be used safely during pregnancy. Toradol is generally contraindicated during pregnancy, especially in the third trimester. It can cause premature closure of the ductus arteriosus in the fetus and may increase the risk of bleeding during delivery. Women who are pregnant or planning to become pregnant should discuss alternative pain management options with their healthcare provider.
Monitoring and Follow-up for Toradol Users
Regular monitoring is essential for patients using Toradol, especially those at higher risk for complications. This may include:
- Periodic blood tests to check kidney and liver function
- Blood pressure monitoring
- Assessment of gastrointestinal symptoms
- Evaluation of cardiovascular risk factors
- Monitoring for signs of bleeding or anemia
How often should patients using Toradol have follow-up appointments. The frequency of follow-up appointments depends on individual patient factors and the duration of Toradol use. For short-term use, a follow-up within 1-2 weeks may be sufficient. Patients using Toradol more frequently or those with underlying health conditions may require more frequent monitoring, potentially every 1-3 months.
Emergency Situations and Toradol Use
While Toradol can be an effective pain management tool, there are situations where its use may lead to emergencies. Recognizing these situations and knowing how to respond is crucial for patient safety.
Signs of a Toradol-related Emergency
- Severe abdominal pain or cramping
- Bloody or black, tarry stools
- Vomiting blood or material that looks like coffee grounds
- Severe headache or blurred vision
- Difficulty breathing or wheezing
- Swelling of the face, throat, or extremities
- Chest pain or irregular heartbeat
- Yellowing of the skin or eyes (jaundice)
What should you do if you suspect a Toradol-related emergency. If you experience any of these symptoms while taking Toradol, stop using the medication immediately and seek emergency medical attention. It’s important to inform healthcare providers about your Toradol use, as well as any other medications or substances you’ve been taking, including alcohol.
Preventing Toradol-related Emergencies
- Follow dosage instructions carefully
- Avoid alcohol consumption while using Toradol
- Inform all healthcare providers about your Toradol use
- Report any unusual symptoms to your doctor promptly
- Do not combine Toradol with other NSAIDs or blood thinners without medical supervision
- Stay hydrated to support kidney function
- Be aware of the signs and symptoms of potential complications
How can patients minimize the risk of Toradol-related emergencies. The best way to prevent emergencies is to use Toradol exactly as prescribed, for the shortest duration necessary. Patients should be proactive in discussing any concerns or side effects with their healthcare provider and should never hesitate to seek medical attention if they experience worrying symptoms.
Future Developments in Pain Management: Alternatives to Toradol
As medical research advances, new approaches to pain management are being developed that may provide alternatives to traditional NSAIDs like Toradol. These developments aim to offer effective pain relief with fewer side effects and risks.
Emerging Pain Management Strategies
- Targeted nanoparticle drug delivery systems
- Gene therapy for chronic pain conditions
- Novel non-opioid analgesics
- Advanced nerve stimulation techniques
- Personalized pain management based on genetic profiling
- Artificial intelligence-assisted pain treatment plans
How might future pain management strategies improve upon current treatments like Toradol. Future developments in pain management aim to provide more targeted therapies that can effectively relieve pain while minimizing systemic side effects. For example, nanoparticle drug delivery systems could potentially deliver pain-relieving medications directly to the site of inflammation or injury, reducing the need for systemic NSAIDs like Toradol.
Will Toradol become obsolete in the future of pain management. While new pain management strategies are promising, it’s unlikely that Toradol will become entirely obsolete in the near future. Instead, it may be used more selectively or in combination with newer therapies to provide comprehensive pain relief while minimizing risks. The goal of future pain management is to have a diverse toolkit of options that can be tailored to each patient’s unique needs and medical history.
The Role of Patient Education in Safe Toradol Use
As pain management strategies evolve, patient education remains a crucial component in ensuring the safe and effective use of medications like Toradol. Informed patients are better equipped to recognize potential side effects, adhere to treatment guidelines, and communicate effectively with their healthcare providers.
- Understanding the proper use and dosage of Toradol
- Recognizing the signs of potential complications
- Being aware of drug interactions, including with alcohol
- Knowing when to seek medical attention
- Communicating effectively about pain levels and treatment efficacy
How can healthcare providers improve patient education regarding Toradol use. Healthcare providers can enhance patient education by using clear, accessible language, providing written materials, and utilizing digital resources such as educational videos or interactive apps. Regular follow-up appointments and open communication channels can also help reinforce important information and address any questions or concerns that arise during treatment.
Toradol and Alcohol/Food Interactions – Drugs.com
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There are 3 alcohol/food/lifestyle interactions with Toradol (ketorolac).
Ask your doctor before using ketorolac together with ethanol. Do not drink alcohol while taking ketorolac. Alcohol can increase your risk of stomach bleeding caused by ketorolac. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Switch to professional interaction data
NSAIDs – fluid retention
Fluid retention and edema have been reported in association with the use of nonsteroidal anti-inflammatory drugs (NSAIDs). Therapy with NSAIDs should be administered cautiously in patients with preexisting fluid retention, hypertension, or a history of heart failure. Blood pressure and cardiovascular status should be monitored closely during the initiation of NSAID treatment and throughout the course of therapy.
References
- “Product Information. Motrin (ibuprofen).” Pharmacia and Upjohn
(2002): - “Product Information. Nalfon (fenoprofen).” Xspire Pharma
(2002): - “Product Information. Indocin (indomethacin).” Merck & Co., Inc
(2002): - “Product Information. Orudis (ketoprofen).” Wyeth-Ayerst Laboratories
(2002): - “Product Information. Naprosyn (naproxen).” Syntex Laboratories Inc
(2002): - “Product Information. Anaprox (naproxen).” Roche Laboratories
(2006): - “Product Information. Clinoril (sulindac).” Merck & Co., Inc
(2001): - “Product Information. Tolectin (tolmetin). ” McNeil Pharmaceutical
(2001): - “Product Information. Relafen (nabumetone).” SmithKline Beecham
(2001): - “Product Information. Feldene (piroxicam).” Pfizer U.S. Pharmaceuticals
(2001): - “Product Information. Ansaid (flurbiprofen).” Pharmacia and Upjohn
(2001): - “Product Information. Lodine (etodolac).” Wyeth-Ayerst Laboratories
(2001): - “Product Information. Daypro (oxaprozin).” Searle
(2001): - “Product Information. Mobic (meloxicam).” Boehringer-Ingelheim
(2001):
View all 14 references
NSAIDs – hypertension
Nonsteroidal anti-inflammatory drugs (NSAIDs), including topicals, can lead to new onset of hypertension or worsening of preexisting hypertension, either of which can contribute to the increased incidence of cardiovascular events. NSAIDs should be used with caution in patients with hypertension. Blood pressure should be monitored closely during the initiation of NSAID therapy and throughout the course of therapy.
References
- “Product Information. Indocin (indomethacin).” Merck & Co., Inc
(2002): - “Product Information. Naprosyn (naproxen).” Syntex Laboratories Inc
(2002): - “Product Information. Voltaren (diclofenac).” Novartis Pharmaceuticals
(2001): - “Product Information. Relafen (nabumetone).” SmithKline Beecham
(2001): - “Product Information. Feldene (piroxicam).” Pfizer U.S. Pharmaceuticals
(2001): - “Product Information. Dolobid (diflunisal).” Merck & Co., Inc
(2001): - “Product Information. Ansaid (flurbiprofen).” Pharmacia and Upjohn
(2001): - “Product Information. Lodine (etodolac).” Wyeth-Ayerst Laboratories
(2001): - “Product Information. Daypro (oxaprozin).” Searle
(2001): - “Product Information. Celebrex (celecoxib).” Searle
(2001): - “Product Information. Meclofenamate Sodium (meclofenamate).” Mylan Pharmaceuticals Inc
(2012): - “Product Information. Flector Patch (diclofenac topical).” Actavis U.S. (Alpharma USPD)
(2016):
View all 12 references
Toradol drug interactions
There are 355 drug interactions with Toradol (ketorolac).
Toradol disease interactions
There are 13 disease interactions with Toradol (ketorolac) which include:
- GI toxicity
- platelet aggregation inhibition
- renal dysfunction
- asthma
- fluid retention
- GI toxicity
- rash
- thrombosis
- anemia
- heart failure
- hepatotoxicity
- hyperkalemia
- hypertension
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Drug Interaction Classification
Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
---|---|
Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Unknown | No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medical Disclaimer
Toradol Injection Drug / Medicine Information
NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia.
Consumer Medicine Information (CMI) summary
The full CMI on the next page has more details. If you are worried about using this medicine,
speak to your doctor or pharmacist.
Why am I using TORADOL?
TORADOL contains the active ingredient ketorolac trometamol. TORADOL is used to relieve
pain and reduce inflammation (swelling and soreness) that may occur following surgery.
For more information, see Section 1. Why am I using TORADOL? in the full CMI.
What should I know before I use TORADOL?
Do not TORADOL if you are pregnant or intend to become pregnant, or if you are breastfeeding
or intend to breastfeed. Do not use TORADOL if you are allergic to TORADOL, aspirin
or any other NSAID medicine, or any of the ingredients listed at the end of this leaflet.
Talk to your doctor if you have any other medical conditions or take any other medicines.
For more information, see Section 2. What should I know before I use TORADOL? in the full CMI.
What if I am taking other medicines?
Some medicines may interfere with TORADOL and affect how it works. A list of these
medicines is in Section 3. What if I am taking other medicines? in the full CMI.
How do I use TORADOL?
TORADOL is given as an injection, into a muscle by a doctor or trained nurse. The
usual dose for healthy adults is 10 mg to 30 mg every 4 to 6 hours, up to a maximum
daily dose of 90 mg. More information can be found in Section 4. How do I use TORADOL? in the full CMI.
What should I know while using TORADOL?
Things you should do | Call your doctor straight away if you become pregnant while receiving TORADOL. Tell your doctor if you get an infection soon after taking TORADOL. |
---|---|
Things you should not do | Do not receive TORADOL for longer than 5 days. Prolonged use may increase the occurrence |
Driving or using machines | Be careful before you drive or use any machines or tools until you know how TORADOL As with other NSAID medicines, TORADOL may cause dizziness or light-headedness in |
Drinking alcohol | Tell your doctor if you drink alcohol. If you drink alcohol, dizziness or light-headedness may be worse. |
Looking after your medicine | TORADOL will be stored in the pharmacy or on the hospital ward. It is kept in a cool |
For more information, see Section 5. What should I know while using TORADOL? in the full CMI.
Are there any side effects?
Call your doctor straight away, or go straight to the Emergency Department at your
nearest hospital if you notice any of these very serious side effects: vomiting blood
or material that looks like coffee grounds, bleeding from the back passage, black
sticky bowel motions or bloody diarrhoea, swelling of the face, lips or tongue which
may cause difficulty in swallowing or breathing, asthma, wheezing, shortness of breath,
sudden or severe itching, skin rash or hives, fainting, seizures or fits, pain or
tightness in the chest, or flu-like symptoms with a rash on the face then an extended
rash with a high temperature and enlarged lymph nodes. Tell your doctor immediately
if you notice any of the following serious side effects: severe dizziness, spinning
sensation, severe or persistent headache, abnormal vision, bleeding or bruising more
easily than normal, reddish or purplish blotches under the skin, severe pain or tenderness
in any part of the stomach or back, unusual weight gain, swelling of ankles or legs.
For more information, including what to do if you have any side effects, see Section
6. Are there any side effects? in the full CMI.
Active ingredient:
ketorolac trometamol
Consumer Medicine Information (CMI)
This leaflet provides important information about using TORADOL. You should also speak to your doctor or pharmacist if you would like further information
or if you have any concerns or questions about using TORADOL.
Where to find information in this leaflet:
1. Why am I using TORADOL?
2. What should I know before I use TORADOL?
3. What if I am taking other medicines?
4. How do I use TORADOL?
5. What should I know while using TORADOL?
6. Are there any side effects?
7. Product details
Why am I using TORADOL?
TORADOL contains the active ingredient ketorolac trometamol. TORADOL belongs to a family of medicines called Non-Steroidal Anti-Inflammatory Drugs
(NSAIDs).
TORADOL is used to relieve pain and reduce inflammation (swelling and soreness) that
may occur following surgery. Although TORADOL can relieve the symptoms of pain and inflammation, it will not cure
your condition.
Your doctor may have prescribed TORADOL for another purpose.
What should I know before I use TORADOL?
Warnings
Do not use TORADOL if:
you are allergic to ketorolac trometamol, aspirin or any other NSAID medicine, or
any of the ingredients listed at the end of this leaflet. Many medicines used to treat
headache, period pain and other aches and pains contain aspirin or NSAID medicines.
If you are not sure if you are taking any of these medicines, ask your doctor or pharmacist.
If you are allergic to aspirin or NSAID medicines and use TORADOL, these symptoms
may be severe. Symptoms of an allergic reaction to these medicines may include:
asthma, wheezing or shortness of breath
swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing
hives, itching or skin rash
fainting
Always check the ingredients to make sure you can use this medicine.
you are pregnant or intend to become pregnant
you are breastfeeding or intend to breastfeed
you have kidney disease
you have severe liver disease
you have severe heart failure
you have recently had or are about to have heart bypass surgery
you have a peptic ulcer (stomach or duodenal ulcer), a recent history of one, or have
had peptic ulcers before
you have had any bleeding disorders
you have asthma
you suffer dehydration
you have nasal polyps syndrome, angioedema or bronchospasm (breathing difficulties)
you have a history of Stevens-Johnsons Syndrome (a rare skin condition with severe
blisters and bleeding in the lips, eyes, mouth, nose and genitals)
you are receiving the following medicines:
other NSAID medicines
probenecid, a medicine used to treat gout
lithium, a medicine used to treat some types of depression
oxpentifylline, a medicine used to treat certain blood disorders
Do not give TORADOL to a child under 16 years of age.
The safety and effectiveness in children under 16 have not
been established.
If you are not sure if you should be given TORADOL,
contact your doctor.
Check with your doctor if you:
have any other medical conditions, especially the following:
heartburn, indigestion, stomach ulcers or other stomach problems
kidney or liver disease
heart failure
high blood pressure or heart problems
swelling of the ankles or feet
inflammatory bowel disease, such as Crohn’s disease
take any medicines for any other condition
you have any allergies to:
any other medicines
any other substances, such as foods, preservatives or dyes
you currently have an infection. TORADOL may hide some of the signs of an infection
(eg pain, fever) and may make you think that the infection is not serious or that
you are better.
you plan to have surgery
you have ever smoked or been a heavy alcohol drinker
If you have not told your doctor about any of the above, tell them before you are
given TORADOL.
During treatment, you may be at risk of developing certain side effects. It is important
you understand these risks and how to monitor for them. See additional information
under Section 6. Are there any side effects?
Pregnancy and breastfeeding
Do not take TORADOL if you are pregnant or intend to become pregnant.
TORADOL may affect your developing baby if you take it during pregnancy. If it is
necessary for you to take TORADOL, your doctor will discuss the risks and benefits
of taking it during pregnancy.
TORADOL may impair fertility and is not recommended in women attempting to conceive.
Do not take TORADOL if you are breast-feeding or intend to breast-feed.
TORADOL passes into breast milk. The effect on the baby is not known.
What if I am taking other medicines?
Tell your doctor or pharmacist if you are taking any other medicines, including any
medicines, vitamins or supplements that you buy without a prescription from your pharmacy,
supermarket or health food shop.
Some medicines may interfere with TORADOL and affect how it works. These include:
aspirin, salicylates or other NSAID medicines (such as ibuprofen or naproxen)
warfarin, a medicine used to stop blood clots
probenecid, a medicine used to treat gout
oxpentifylline, a medicine used to treat certain blood disorders
lithium, a medicine used to treat some types of depression
selective serotonin reuptake inhibitors (SSRIs), medicines used to treat depression
(such as fluoxetine, paroxetine or citalopram)
thiothixene, a medicine used to treat psychosis
diuretics, also called fluid or water tablets
phenytoin, a medicine used to treat epilepsy
carbamazepine, a medicine used to treat epilepsy
methotrexate, a medicine used to treat arthritis and some cancers
heparin, a medicine used to treat blood disorders
medicines used to treat high blood pressure, including ACE inhibitors, angiotensin
receptor antagonists and beta-blockers.
certain antibiotics called aminoglycosides
You may need to use different amounts of your medicine, or you may need to use different
medicines. Your doctor will advise you.
Check with your doctor or pharmacist if you are not sure about what medicines, vitamins
or supplements you are taking and if these affect TORADOL.
How do I use TORADOL?
How TORADOL is given
TORADOL is given as an injection, into a muscle by a doctor or trained nurse.
The injection should not be injected directly into the veins (intravenously).
Your doctor will decide what dose of TORADOL you will receive. This depends on your
condition.
The usual dose for healthy adults is 10 mg to 30 mg every 4 to 6 hours, up to a maximum
daily dose of 90 mg.
If you are over 65 years old or have reduced kidney function, your doctor may prescribe
a lower dose.
When TORADOL is given
TORADOL injection is given every 4 to 6 hours as required, up to a maximum daily dose
of 90 mg
How long TORADOL is given for
Do not receive TORADOL for longer than 5 days. Prolonged use may increase the occurrence of side effects.
If you use too much TORADOL
If you receive too much TORADOL, you may have pain or tenderness in the stomach, stomach
upset including nausea (feeling sick), vomiting, heartburn, indigestion or cramps.
If you think that you have used too much TORADOL, you may need urgent medical attention.
You should immediately:
phone the Poisons Information Centre
(by calling
13 11 26), or
contact your doctor, or
go to the Emergency Department at your nearest hospital.
You should do this even if there are no signs of discomfort or poisoning.
If you are not sure what to do, contact your doctor or pharmacist.
What should I know while using TORADOL?
Call your doctor straight away if you:
become pregnant while receiving TORADOL
get an infection soon after receiving TORADOL. TORADOL may hide some of the signs
of an infection and may make you think, mistakenly, that the infection is not serious
or that you are better. Signs of an infection may include fever, pain, swelling and
redness.
Remind any doctor, dentist or pharmacist you visit that you are using TORADOL.
If you are going to have surgery tell your doctor you are being given TORADOL.
Driving or using machines
Be careful before you drive or use any machines or tools until you know how TORADOL
affects you.
As with other NSAID medicines, TORADOL may cause dizziness or light-headedness in
some people. Make sure you know how you react to TORADOL before you drive a car, operate
machinery, or do anything else that could be dangerous if you are dizzy or light-headed.
If this occurs do not drive.
Drinking alcohol
Tell your doctor if you drink alcohol.
If you drink alcohol, dizziness or light-headedness may be worse.
Looking after your medicine
TORADOL will be stored in the pharmacy or on the hospital ward. It is kept in a cool
dry place where the temperature stays below 30°C. It should be protected from light.
Getting rid of any unwanted medicine
If you no longer need to use this medicine or it is out of date, take it to any pharmacy
for safe disposal.
Do not use this medicine after the expiry date.
Are there any side effects?
All medicines can have side effects. If you do experience any side effects, most of
them are minor and temporary. However, some side effects may need medical attention.
See the information below and, if you need to, ask your doctor or pharmacist if you
have any further questions about side effects.
Other side effects not listed here may occur in some people. Tell your doctor if you
notice anything else that is making you feel unwell.
Less serious side effects
Less serious side effects | What to do |
---|---|
Gastrointestinal or gut related: stomach upset including nausea (feeling sick), heartburn, indigestion pain in the stomach or wind diarrhoea Head related: dizziness drowsiness headache dry mouth feeling extremely thirsty Skin related: skin rash or hives sweating Muscle related: aching muscles, muscle tenderness or weakness, not caused by exercise Injection related: pain at site of injection Urinary or bladder related: passing more or less urine than normal | Speak to your doctor if you have any of these less serious side effects and they worry |
Serious side effects
Very serious side effects
Serious side effects | What to do |
---|---|
Gastrointestinal or gut related: vomiting blood or material that looks like coffee grounds bleeding from the back passage (rectum), black sticky bowel motions (stools) or bloody Allergic reaction related: swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing asthma, wheezing, shortness of breath sudden or severe itching, skin rash or hives fainting, seizures or fits pain or tightness in the chest flu-like symptoms with a rash on the face then an extended rash with a high temperature, | Call your doctor straight away, or go straight to the Emergency Department at your |
Tell your doctor or pharmacist as soon as possible if you do not feel well while you
are receiving TORADOL.
Reporting side effects
After you have received medical advice for any side effects you experience, you can
report side effects to the Therapeutic Goods Administration online at www.tga.gov.au/reporting-problems . By reporting side effects, you can help provide more information on the safety of
this medicine.
Product details
This medicine is only available with a doctor’s prescription.
TORADOL is not addictive.
What TORADOL contains
Active ingredient (main ingredient) | each 10 mg/mL TORADOL injection contains 10 mg of ketorolac trometamol each 30 mg/mL TORADOL injection contains 30 mg of ketorolac trometamol |
---|---|
Other ingredients (inactive ingredients) | ethanol sodium chloride sodium hydroxide or hydrochloric acid water for injections |
Potential allergens | TORADOL does not contain sucrose, gluten, tartrazine or any other azo dyes. |
Do not take this medicine if you are allergic to any of these ingredients.
What TORADOL looks like
TORADOL is a clear to slightly yellow solution in 1 mL glass ampoules. TORADOL comes
in packs of 5 ampoules.
TORADOL 10 mg/mL injection (AUST R 34356)
TORADOL 30 mg/mL injection (AUST R 34357)
TORADOL is also available as a tablet.
Who distributes TORADOL
TORADOL is supplied in Australia by:
Clinect Pty Ltd
120 – 132 Atlantic Drive
Keysborough VIC 3173
Australia
Customer enquiries: 1 800 899 005
Sponsor:
Atnahs Pharma Australia Pty Ltd
Level 10
10 Shelley Street,
SYDNEY, NSW, 2000, Australia
This leaflet was prepared in August 2021.
What you need to know before taking Toradol for pain – Drink-Drink
Contents
- What is a drug?
- What is Toradol?
- What is it used for?
- Side effects and warnings
- Other painkillers
- Conclusion
Review
Toradol is a non-steroidal anti-inflammatory drug (NSAID). It’s not a drug.
Toradol (general name: ketorolac) is not addictive, but it is a very strong NSAID and can lead to serious side effects. You also shouldn’t take it for a long period of time.
Read on to learn about the uses and dangers of toradol and how to take it correctly.
What is a drug?
Narcotic is another name for an opioid, which is a drug made from opium or a synthetic (laboratory/man-made) substitute for opium. These prescription-only medicines help manage pain, suppress coughs, cure diarrhea, and help people sleep. There are also illegal drugs such as heroin.
Drugs are very strong drugs that are highly addictive. They can cause serious problems, including nausea and vomiting, decreased physical activity, constipation, and slow breathing. It is possible to overdose on drugs and they can be fatal.
Therefore drugs are considered controlled substances. A controlled substance is a drug that is regulated by federal law. They are placed on “lists” based on their medical use, potential for abuse, and safety. Drugs for medical use are Schedule 2, which means that they generally have a high potential for abuse that can lead to severe psychological or physical dependence.
What is Toradol?
Toradol is a prescription NSAID. NSAIDs are medicines that reduce the amount of prostaglandins, substances in the body that cause inflammation. However, doctors are not entirely sure how it works. NSAIDs are used to reduce inflammation, swelling, fever, and pain.
Toradol is not made from opium (or a synthetic version of opium), so it is not a drug. It’s also non-addictive. Because Toradol is not addictive, it is not regulated as a controlled substance.
However, Toradol is very effective and is only used for short-term pain relief of five days or less. It comes in the form of injections and tablets, or it can be given intravenously (IV). It also comes as an intranasal solution that you spray into your nose. Toradol is often used after surgery, so you can get it first by injection or intravenously and then take it by mouth.
What is it used for?
Toradol is used for moderately severe pain that may otherwise require opioids. You should not use it for minor or chronic pain.
Your doctor may prescribe you Toradol after your surgery. This is the most common use of this medicine. If you are receiving Toradol after surgery, your doctor will give you the first dose as an injection into a muscle or intravenously. Toradol can also be used in the emergency department for acute pain, including sickle cell crises and other severe pain.
It is also used off-label for migraine.
Side effects and warnings
Toradol may cause minor side effects similar to other side effects of NSAIDs. This includes:
- Headache
- dizziness
- drowsiness
- upset stomach
- nausea/vomiting
- diarrhea
Possible and more serious side effects. Because Toradol is much more effective than over-the-counter NSAIDs, serious side effects are more likely to occur. This includes:
- Heart attack or stroke. You should not take Toradol if you have recently had a heart attack, stroke, or heart surgery.
- Bleeding, especially in your stomach. Do not take Toradol if you have a history of ulcers or gastrointestinal bleeding.
- Ulcers or other intestinal or stomach problems.
- Kidney or liver disease.
Because of these potential side effects, you should not take Toradol with other NSAIDs (including aspirin) or if you are taking steroids or blood thinners. You also should not smoke or drink while taking Toradol.
Other painkillers
There are many types of painkillers other than Toradol. Some are available without a prescription and some are only available from your doctor. Below are some common pain relievers and their types.
Ibuprofen (Advil, Motrin) | OTC NSAID | |
Naproxen (Aleve) | OTC NSAID | |
Acetaminophen (Tylenol) | OTC pain reliever | |
Aspirin | OTC NSAID | |
Corticosteroids | Steroid | opioid |
Morphine | opioid | |
Tramadol | opioid 97 Oxycodone ( OxyContin) | opioid |
Codeine | opioid |
Conclusion
Toradol is not a drug, but it can still have serious side effects. If your doctor prescribes Toradol for you, be sure to discuss with him the best way to take it, how long to take it, and what symptoms of side effects you should be aware of. When taken properly, Toradol can help you manage short-term, moderate pain or moderately severe pain without the potential for opioid dependence.
Ketorolac (Systemic: Pediatric Medication | Memorial Sloan Kettering Cancer Center
Pediatric Medicine
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This document, provided by Lexicomp ® , contains all the information you need to know about this medicine, including indications, directions for use, side effects, and when your healthcare provider should be contacted.
Trade names: USA
ReadySharp Ketorolac [DSC]
Brand names: Canada
ALTI-Ketorolac; APO-Ketorolac; JAMP Ketorolac; Mar-Ketorolac; MINT-Ketorolac; Toradol
Warning
All Forms:
- This drug may increase the risk of heart and blood vessel side effects such as heart attack and stroke. These side effects can be deadly if they occur. The risk of these side effects may be increased if your child has or is at risk of developing heart disease. However, the risk may also be higher for people who do not have heart disease or are not at risk of developing heart disease. The risk of these health problems may begin immediately during the first weeks of using this drug and may increase with higher doses or long-term use of the drug. This drug should not be given to a child immediately before or after coronary bypass surgery.
- This drug may increase the chance of developing severe and sometimes deadly stomach or intestinal problems, such as ulcers or bleeding. The risk is increased in the elderly and in people who have previously had ulcers or bleeding in the stomach or intestines. Such disturbances can occur suddenly.
- This drug should only be used to treat short-term pain (up to 5 days in total). When taken for more than 5 days, the drug can cause the development of dangerous side effects.
- Do not give your child more than the amount of this drug prescribed by the doctor. Taking more than what is prescribed for this drug may increase the risk of serious side effects.
- Do not use on a child for longer than prescribed by your child’s doctor.
- You should not give this drug if your child has a peptic ulcer, very bad kidney problems, or is at risk of developing kidney problems due to low blood volume, or is at high risk of bleeding or active bleeding such as a cerebral hemorrhage .
- Tell your doctor if your child has kidney problems or weighs less than 110 pounds (50 kilograms).
- Do not give this drug to your child if they have had an allergic reaction to this drug, aspirin, or other non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen in the past.
- Do not give to prevent pain before surgery.
- Do not give in combination with aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen.
- This drug is not approved for use in children. Consult your doctor.
If your daughter is pregnant:
- Do not give the drug if your daughter is pregnant or giving birth:
Injection:
- This drug is not injected into the spine.
What is this drug used for?
- Used to relieve pain.
What do I need to tell the doctor BEFORE my child takes this drug?
- If your child has an allergy to this drug, any of its ingredients, other drugs, foods, or substances. Tell the doctor about the allergy and how it manifested itself in the child.
- If your child has had nasal polyps or swelling of the mouth, face, lips, tongue, or throat; unusual hoarseness; or difficulty breathing while taking aspirin or NSAIDs.
- If your child has any of these health problems: gastrointestinal bleeding, kidney disease, or peptic ulcers.
- If your child has heart failure (weakened heart).
- If your child has recently had a heart attack.
- If your child is being tested for fertility.
- If your child is taking any of the following drugs: pemetrexed, pentoxifylline, probenecid, a salicylate drug such as aspirin, or any other NSAID.
If your daughter is pregnant:
- If your daughter is pregnant, planning to become pregnant, or becomes pregnant while taking this drug, talk with your doctor. If you take this drug after 20 weeks of pregnancy, it may harm the fetus. If your daughter is 20 to 30 weeks pregnant, give this drug only as directed by your doctor. Do not give this drug to your daughter if she is more than 30 weeks pregnant.
This list of drugs and conditions that may interfere with this drug is not all inclusive.
Talk to your doctor or pharmacist about all medicines your child is taking (prescription and over-the-counter, natural, and vitamins) and any health problems. You need to make sure that this drug is safe to use for your child’s illnesses and in combination with other drugs he or she is already taking. Do not start, stop taking, or change the dosage of any drug your child is taking without the doctor’s approval.
What do I need to know or do while my child is taking this drug?
- Tell all health care providers who care for your child that your child is taking this drug. These are your child’s doctors, nurses, pharmacists and dentists.
- Perform blood tests as directed by your doctor. Consult with your doctor.
- The use of drugs of this kind was accompanied by high blood pressure. Monitor your child’s blood pressure as directed by your doctor.
- Your child may become more prone to bleeding. Make sure your child is careful to avoid injury. Make sure your child uses a soft toothbrush.
- If your child has asthma, check with your doctor. The child may be hypersensitive to this drug.
- Alcohol can interact with this drug. Make sure your child does not drink alcohol.
- If your child smokes, check with your doctor.
- The risk of developing heart failure increases with the use of drugs of this kind. People with heart failure have an increased risk of myocardial infarction, hospitalization for heart failure, and death. Consult your doctor.
- People who have had a heart attack and are taking this type of drug are at increased risk of having another heart attack and dying from a heart problem. People who took drugs of this kind after their first myocardial infarction were also more likely to die one year after myocardial infarction than those who did not take such drugs. Consult your doctor.
- There was a serious reaction that could be deadly. In most cases, this reaction was accompanied by symptoms such as fever, rash, inflammation of the lymph nodes, and dysfunction of various organs such as the liver, kidneys, blood, heart, muscles, joints and lungs. If you have any questions, please consult your doctor.
If your child is or may be sexually active:
- Non-steroidal anti-inflammatory drugs (NSAIDs), such as this drug, may interfere with the release of an egg (ovulation). This can negatively affect the ability to get pregnant. As a rule, the process of ovulation is restored after stopping this drug. Consult your doctor.
If your daughter is breastfeeding:
- Tell your doctor if your daughter is breastfeeding. You will need to be counseled about the possible risks to the child.
What side effects should I report to my child’s doctor right away?
WARNING/CAUTION: Although rare, some people may have very serious and sometimes deadly side effects from this drug. Call your child’s doctor right away or get medical help if your child has any of the following signs or symptoms that could be associated with a very bad side effect:
- Signs of an allergic reaction, such as rash, hives, itching, red and swollen skin with blisters or peeling, possibly accompanied by fever, wheezing or wheezing, tightness in the chest or throat, difficulty breathing, swallowing or speaking, unusual hoarseness, swelling in the mouth, face, lips, tongue or throat. In rare cases, some allergic reactions have resulted in death.
- signs of bleeding, such as vomiting or coughing up blood; vomiting of the type of coffee grounds; blood in the urine; black, red, or tarry stools; bleeding from the gums; non-cyclic vaginal bleeding; bruises that appear or increase for no reason; bleeding that you cannot stop.
- Signs of kidney problems, including not passing urine, changes in the volume of urine, blood in the urine, or rapid weight gain.
- Signs of elevated potassium levels such as feeling of an abnormal heartbeat, confusion, feeling weak or dizzy, feeling faint, feeling numb or tingly, or short of breath.
- Signs of high blood pressure, such as a very severe headache, or dizziness, or loss of consciousness, or blurred vision.
- Pain or pressure in the chest.
- Weakness on 1 side of the body, difficulty speaking or thinking, problems with balance, sagging on one side of the face, or blurred vision.
- Shortness of breath, sudden weight gain, or swelling of the arms or legs.
- Feeling extremely tired or weak.
- Swelling of the gland.
- The use of drugs like this has been associated with liver problems. In some cases, this has led to death. Call your doctor right away if your child shows signs of liver problems, such as dark urine, fatigue, decreased appetite, nausea or abdominal pain, light-colored stools, vomiting, yellowing of the skin or eyes.
- Severe skin reactions have occurred during treatment with this drug. These include Stevens-Johnson syndrome (SSD), toxic epidermal necrolysis (TEN), and other severe skin reactions. In some cases, this has led to death. Seek medical attention right away if your child has symptoms such as redness, swelling of the skin, blistering or peeling, other skin irritations (with or without a fever), red or irritated eyes, sores in the mouth, throat, nose, or eyes.
What are some other side effects of this drug?
Any drug can cause side effects. However, for many people, side effects are either minor or non-existent. Contact your child’s doctor or seek medical attention if any of these or other side effects bother your child or if they persist:
- Headache.
- Abdominal pain or heartburn.
- Nausea.
This list of possible side effects is not exhaustive. If you have any questions about side effects, ask your child’s doctor. Talk to your child’s doctor about side effects.
You can report side effects to the National Health Board.
What is the best way to give this drug?
Give this drug to your child as directed by your doctor. Read all the information provided to you. Strictly follow all instructions.
Tablets:
- Give this drug with or without food. If the drug causes stomach upset, give it with food.
Injection:
- For intramuscular or intravenous injections.
What if my child misses a dose of medication?
Tablets:
- If the child takes the drug regularly, give him the missed dose as soon as you remember about it.
- If it is time for your child to take the next dose, do not take the missed dose and then go back to your child’s normal schedule.
- Do not give a double dose at the same time or additional doses.
- In most cases, this drug is used as needed. Do not give your child the drug more often than prescribed by the doctor.
Injection:
- Contact your child’s doctor to find out the next steps.
How do I store and/or discard this drug?
Tablets:
- Store at room temperature, protected from light. Store in a dry place. Do not store in the bathroom.
Injection:
- If you need to store this drug at home, check with your child’s doctor, nurse, or pharmacist about how to store it.
All forms:
- Keep all medicines in a safe place. Keep all medicines out of the reach of children and pets.
- Dispose of unused or expired drugs. Do not empty into a toilet or sewer unless instructed to do so. If you have any questions about disposing of medicines, ask your pharmacist. Drug disposal programs may be in place in your area.
General drug information
- If your child’s symptoms or health problems do not improve, or worsen, contact your child’s doctor.
- Do not share your child’s medicine with others and do not give anyone else’s medicine to your child.
- Some medicines may come with other patient information leaflets. If you have questions about this drug, talk with your child’s doctor, nurse, pharmacist, or other health care professional.
- If you think you have overdosed, call a poison control center or get medical help right away. Be prepared to tell or show what drug you took, how much, and when it happened.
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This summary information includes a summary of the diagnosis, treatment, and/or drug product. It is not intended to be a comprehensive source of data and should be used as a tool to help the user understand and/or evaluate potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a particular patient. It should not be considered medical advice or a substitute for medical advice, diagnosis or treatment provided by a physician based on a medical examination and assessment of the patient’s specific and unique circumstances. Patients should consult with their physician for full information about their health, medical issues, and treatment options, including any risks or benefits regarding the use of medications. This information is not a guarantee that a treatment or drug is safe, effective, or approved for a particular patient. UpToDate, Inc. and its subsidiaries disclaim any warranties or liabilities related to this information or its use. The use of this information is subject to the Terms of Use found at https://www.