What are the benefits of vitamin D3? How much vitamin D3 should you take daily? Explore the uses, side effects, and interactions of cholecalciferol in this informative article.

The Remarkable Benefits of Vitamin D3

Vitamin D3, also known as cholecalciferol, is an essential nutrient that plays a vital role in maintaining overall health and well-being. Far beyond its well-known benefits for bone health, vitamin D3 offers a wide range of advantages that may surprise you. In this comprehensive guide, we’ll dive into 17 remarkable benefits of this remarkable vitamin.

Strengthening Bones and Teeth

Vitamin D3 is essential for the proper absorption and utilization of calcium, the primary mineral found in our bones and teeth. By facilitating calcium metabolism, vitamin D3 helps to build and maintain strong, healthy bones, reducing the risk of osteoporosis and fractures. It also plays a crucial role in maintaining the integrity of our teeth.

Boosting the Immune System

Vitamin D3 is a powerful ally in supporting the immune system. It stimulates the production of T-cells, which are responsible for recognizing and responding to viral infections, such as the common cold, influenza, and other illnesses caused by viruses, bacteria, and fungi. By enhancing the immune system’s function, vitamin D3 can help the body fight off these common ailments more effectively.

Potential Cancer Prevention

Emerging research suggests that vitamin D3 may play a role in preventing certain types of cancer. Epidemiological studies have shown that individuals who live in southern or equatorial regions, where they are exposed to more sunlight, have a lower risk of developing certain cancers. Vitamin D3 is believed to aid in the repair and regeneration of cells, potentially slowing the growth of cancer cells.

Improved Brain Function and Mood

Vitamin D3 has been linked to improved brain function and cognitive performance. It may also have a positive impact on mood, potentially helping to alleviate symptoms of depression. By supporting the proper functioning of the nervous system, vitamin D3 can contribute to overall mental well-being.

Weight Management and Diabetes Prevention

Interestingly, vitamin D3 has been associated with weight management and reduced risk of type 2 diabetes. It may help in weight loss efforts and can potentially lower the risk of developing this metabolic disorder. By regulating various physiological processes, vitamin D3 can play a role in maintaining a healthy weight and glucose metabolism.

Versatile Health Benefits

The benefits of vitamin D3 extend beyond the areas mentioned so far. It has been linked to reduced risk of heart disease, lower blood pressure, decreased inflammation, improved oral health, and even better lung function and nervous system support. Vitamin D3 truly is a multifaceted nutrient with a wide range of health-promoting properties.

Now that we’ve explored the remarkable benefits of vitamin D3, let’s dive into the details of how this essential nutrient works in the body.

Understanding Vitamin D3

Vitamin D is a unique nutrient in that it can be synthesized by the body when the skin is exposed to sunlight. Specifically, vitamin D3 (cholecalciferol) is produced in the skin when ultraviolet-B (UVB) rays from the sun interact with a precursor molecule.

However, the amount of vitamin D3 produced through sun exposure can vary greatly depending on factors such as age, skin pigmentation, season, latitude, time of day, clothing habits, and sunscreen use. As a result, many individuals may not be able to obtain sufficient vitamin D3 from sunlight alone, necessitating dietary sources or supplementation.

Optimal Vitamin D3 Intake

There is no established Recommended Dietary Allowance (RDA) for vitamin D3. The Institute of Medicine (IOM) recommends a daily intake of 600 IU (15 mcg) for most adults between the ages of 19 and 70 years, including pregnant and lactating women.

However, certain populations, such as older adults, individuals with dark skin, and those with limited sun exposure, may require higher intakes to maintain optimal vitamin D3 levels. The IOM has set an Upper Limit (UL) of 4,000 IU (100 mcg) per day to avoid potential adverse health effects associated with excessive vitamin D3 intake.

It’s important to note that the optimal vitamin D3 intake can vary from person to person, and it’s always best to consult with a healthcare professional to determine the appropriate dosage based on your individual needs and circumstances.

Vitamin D3 Interactions and Side Effects

While vitamin D3 is generally considered safe when taken within the recommended range, it’s important to be aware of potential interactions and side effects. Vitamin D3 may interact with certain medications, such as cholestyramine, corticosteroids, and some antiseizure drugs. It’s crucial to discuss any supplements you’re taking with your healthcare provider to avoid potential conflicts.

Excessive intake of vitamin D3 can lead to side effects like nausea, vomiting, loss of appetite, constipation, weakness, and kidney problems. It’s essential to follow the recommended dosages and to seek medical advice if you experience any adverse reactions.

In summary, vitamin D3 is a remarkable nutrient with a wide range of health benefits, from strengthening bones and teeth to supporting the immune system and potentially preventing certain types of cancer. Understanding how to optimize your vitamin D3 intake and being mindful of potential interactions and side effects can help you harness the full power of this essential vitamin.

17 Vitamin D3 Benefits Everyone Should Know

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Did you know that vitamin D is actually a hormone? It’s true! And it’s one of the most important hormones in the body. Vitamin D is essential for good health, and there are many benefits to be had from getting enough of it.

In this blog post, we will discuss 17 of the best vitamin D3 benefits. So whether you’re looking to improve your overall health or just want to learn more about this important nutrient, read on.

1.      It strengthens bones.

2.      It strengthens the immune system.

3.      It might prevent certain types of cancer.

4.      It may improve brain function.

5.      It boosts your mood.

6.      It can aid in weight loss.

7.      It can lower the risk of rheumatoid arthritis.

8.      It lowers the risk of type 2 diabetes.

9.      It can help lower blood pressure.

10.   It might reduce the risk of heart disease.

11.   It can fight inflammation.

12.   It can strengthen oral health.

13.   It can reduce risk of fractures.

14.   It supports proper lung function.

15.   It can support a healthy nervous system.

16.   It can encourage healthy hair growth.

17.   It can improve cognitive function and prevent dementia.

How does vitamin D3 work?

Vitamin D is a fat-soluble vitamin that can be found in only a few foods, added to others, and obtained as a dietary supplement. It’s also made naturally by the body when sunlight hit the skin and stimulate vitamin D synthesis.

Vitamin D obtained from sun exposure, food, and supplements is biologically inert and must undergo two hydroxylations in the body for activation. The first occurs in the liver and converts vitamin D to 25-hydroxyvitamin D [25(OH)D], also known as calcidiol.

Calcitriol circulates as a hormone in the blood and regulates calcium and phosphate metabolism for bone formation and other physiological functions. Vitamin D sufficiency is achieved when serum 25(OH)D concentrations are ≥30 ng/mL (75 nmol/L).

Most vitamin D is derived from sun exposure; however, the amount of sun exposure required to maintain adequate levels varies by age, skin pigmentation, season, latitude, time of day, clothing habits, and use of sunscreen.

People who have limited sun exposure need to include good sources of vitamin D in their diet or take supplements to achieve and maintain adequate serum 25(OH)D concentrations.

How much vitamin D3 should a person take?

There is no Recommended Dietary Allowance (RDA) for vitamin D. The Institute of Medicine (IOM) recommends a daily intake of 600 IU (15 mcg) of vitamin D for most adults between the ages of 19 and 70 years, including pregnant and lactating women.

The IOM set an Upper Limit (UL) of 4000 IU (100 mcg) per day for adults to avoid the potential risk of adverse health effects associated with excessive vitamin D intake.

Pregnant and lactating women, as well as people over the age of 70 years, are advised to get more than 600 IU/day because they are at increased risk for vitamin D deficiency.

People with dark skin are at increased risk for vitamin D deficiency and may need higher intakes of vitamin D. Some researchers recommend that people with dark skin should get up to 1000-2000 IU (25-50 mcg) of vitamin D per day.

A number of factors can affect how much vitamin D you need, including your age, skin color, and level of sun exposure. Talk to your healthcare provider about how much vitamin D you should take.

What are the benefits of taking vitamin D?

There is some evidence that vitamin D may have a number of health benefits, including:

1. Strengthens Bones

Vitamin D3 aids in the management and absorption of calcium, as well as being essential to your bones (and teeth).

Calcium is the most common mineral in the body. The majority of this element is found in our bones and teeth. Calcium consumption should be sufficient to maintain your bones and teeth healthy. Inadequate calcium intake can result in joint pain with early-onset osteoarthritis and tooth loss.

2. Strengthens the Immune System

Vitamin D’s most important functions include supporting the immune system and improving its function. It stimulates T-cell production and aids in the proper response to viral infections, such as the common cold, influenza, and other community-wide illnesses caused by viruses, bacteria, and fungus.

3. Might Prevent Certain Types of Cancer

Vitamin D3 can assist decrease the chance of developing particular types of cancer. Epidemiological studies have shown that people who reside in southern/equatorial regions and are more exposed to the sun have a lower risk of some malignancies.

Vitamin D has been linked to cancer in numerous studies. Vitamin D aids in the repair and regeneration of cells, which might slow the growth of cancerous tumors, stimulate the death of cells that have been damaged by cancer, and decrease blood vessel formation in tumors.

4. Improve Brain Function 

Vitamin D has been linked to a variety of bodily processes, including the brain’s function. Vitamin D receptors may be found in all parts of the brain and spinal cord. Vitamin D helps you by promoting nerve growth and repair as well as stimulating and inhibiting neurotransmitter synthesis.

Vitamin D, it is thought, benefits the brain by lowering inflammation and preserving neurons. Vitamin D has also been shown to protect neurons in animal studies, which may help to explain why it promotes alertness and quick reaction time.

Another study looked at the relationship between Vitamin D levels and performance on mental tests in a group of people. This research revealed that those with lower Vitamin D levels did worse than those with sufficient amounts, suggesting it improves attention.

5. Boosts Your Mood 

The diminished sunlight exposure in the winter, as well as the darker months, is advantageous for Vitamin D. A number of studies have shown that low levels of Vitamin D3, linked to insufficient sunshine exposure, are associated with Seasonal Affective Disorder (SAD) symptoms.

SAD is a mood disorder characterized by sadness as the primary symptom. Vitamin D3 levels have been shown to decrease, which has been linked to lower levels of serotonin in the brain, a neurotransmitter that controls emotions. You may improve your mood by taking a Vitamin D3 supplement or increasing your sun exposure.

6. Aids in Weight Loss

Did you know that Vitamin D has other benefits? If you’ve been trying to reduce weight and haven’t seen the desired results, consider upping your vitamin D3 intake through diet and sunlight.

Studies have shown that taking a Vitamin D3 supplement, eating more foods that are high in this vitamin, or simply exposing oneself to more sunshine – along with eating a healthy diet and exercising – can help one lose weight. Because Vitamin D3 can assist reduce body fat levels.

People who have insufficient Vitamin D are more likely to become overweight and develop obesity-related diseases, according to studies. However, remember that simply taking a pill, eating more Vitamin D-rich foods, and spending more time in the sun isn’t enough; you’ll also need to eat a balanced diet and exercise regularly.

7. Lower the Risk of Rheumatoid Arthritis

Vitamin D deficiency has been linked to rheumatoid arthritis – a chronic inflammatory disease of the joints. Rheumatoid arthritis is an autoimmune disorder.

The linings of the joints are mistaken by the immune system for foreign materials, resulting in inflammation and stiffness.

A lack of Vitamin D might lead to the development of rheumatoid arthritis since it is required for the immune system’s proper functioning. Raising your Vitamin D levels has the potential to alleviate the severity and incidence of this disease as well as other autoimmune disorders.

8. Lowers the Risk of Type 2 Diabetes

If you have diabetes in your family or have been diagnosed with pre-diabetes, you might want to consider taking more Vitamin D. Recent studies have shown a link between Vitamin D deficiency, insulin resistance, and type 2 diabetes. You may be able to prevent the development of type 2 diabetes by overcoming insulin resistance.

The cells in the pancreas that produce insulin have alpha-hydroxylase enzymes and VDRs, which are important in determining glucose tolerance and resistance to insulin.

Vitamin D deficiency can also reduce the secretion of insulin from the pancreas, which might cause insulin resistance and modify how the body responds to glucose. Given these findings, it is a good idea to consult with your doctor to see if taking extra Vitamin D improves your overall health.

9. Lowers Blood Pressure

Low Vitamin D levels have been linked to high blood pressure in several long-term studies.

It was previously unknown whether Vitamin D insufficiency causes hypertension, but a large genotypic research with over 150,000 participants has revealed that low levels of Vitamin D can induce high blood pressure.

Those who had the most vitamin D in this research had lower blood pressure. It was revealed that an increase of 10% in Vitamin D levels resulted in a 10% reduction in high blood pressure. An increase in your Vitamin D levels may help if you have high blood pressure or wish to prevent it from developing.

10. Reduces Risk of Heart Disease

Vitamin D deficiency has been linked to a variety of health problems, including high blood pressure, heart disease, congestive heart failure, peripheral arterial disease, strokes, and heart attack. Vitamin D levels can be elevated to help reduce the chance of developing heart illness and its symptoms.

Furthermore, because it may aid in weight reduction and maintaining healthy body weight, this vitamin might also be able to minimize the negative effects of obesity and excessive body fat on heart disease. To discover more about Vitamin D advantages, consult with your doctor.

11. Vitamin D can fight inflammation

Vitamin D is beneficial to the immune system because it helps regulate the production of cytokines. Cytokines are proteins that are used by the immune system to communicate with other cells, and when they are produced in the wrong amounts or at the wrong time, they can cause inflammation.

Vitamin D can also help reduce the risk of infections by promoting the production of white blood cells and increasing the efficiency of T-cells. A lack of Vitamin D has been linked to an increased susceptibility to infection, so maintaining healthy levels might help keep you from getting sick.

12. Vitamin D can help Strengthen Oral Health

Vitamin D helps our bodies absorb calcium, which is essential for dental health. Vitamin D has been shown to be beneficial for oral health, according to a 2011 analysis published in The Journal of the Tennessee Dental Association.

13. Reduces the Risk of Fractures

Vitamin D is essential for strong bones. It helps the body absorb calcium, which is necessary for bone health. A lack of vitamin D can lead to a condition called osteoporosis, which weakens bones and makes them more susceptible to fractures.

14. Supports Proper Lung Function

Vitamin D is essential for proper lung function. It helps the body absorb calcium, which is necessary for healthy lungs. A lack of vitamin D has been linked to a variety of respiratory problems, including asthma and COPD.

15. Supports a Healthy Nervous System

Vitamin D is essential for a healthy nervous system. It helps the body absorb calcium, which is necessary for healthy nerves. A lack of vitamin D has been linked to a variety of neurological problems, including Alzheimer’s disease and dementia.

16. Encourages Healthy Hair Growth

Vitamin D is essential for healthy hair growth. It helps the body absorb calcium, which is necessary for healthy hair follicles. A lack of vitamin D has been linked to a variety of hair problems, including hair loss and alopecia.

17. Improves Cognitive Function and Prevents dementia 

Vitamin D is essential for brain development, and a lack of it has been linked to cognitive problems and dementia. A 2017 study published in the journal Neurology found that people with vitamin D deficiency were more likely to experience a decline in cognitive function over a six-year period than those who had sufficient levels of the vitamin.

Should everyone be taking vitamin D3?

There are many benefits of vitamin D, and it’s often called the “sunshine vitamin” because we can produce it when our skin is exposed to sunlight. Vitamin D is important for strong bones and teeth, and it helps our bodies absorb calcium.

It also supports our immune system and may help prevent certain chronic diseases such as cancer.

There are several ways to get vitamin D, including exposure to sunlight, certain foods, and supplements. Vitamin D deficiencies are relatively common, especially in the winter months when there is less sun exposure.

If you think you may be deficient in vitamin D, talk to your doctor about getting a blood test. You may also want to consider taking a supplement, especially if you don’t get much sun exposure.

Image courtesy Elm & Rye

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While we do love so many of the Elm & Rye supplements, today we’re sharing their D3 capsules and D3 gummies so that you can rest easier knowing you’re taking a GMO-free, gluten-free, and dairy-free D3 supplement for your vitamin D deficiency.

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How do you know you are vitamin D deficiency?

There are a few ways to know if you are vitamin D deficient. The most common way is to get your blood tested by a doctor. You can also look for symptoms of deficiency, which include fatigue, bone pain, and muscle weakness.

If you think you might be deficient, it’s important to talk to your doctor and get a blood test. Vitamin D deficiency can be treated with supplements, so it’s important to get diagnosed and treated early.

Can taking too much vitamin D3 hurt you?

Although vitamin D is essential for good health, taking too much of it can be harmful. Vitamin D toxicity can cause nausea, vomiting, weakness, and poor appetite. It can also lead to more serious problems such as kidney stones and heart arrhythmias.

If you take too much vitamin D, be sure to drink plenty of fluids and get some rest. You may also want to see your doctor to be sure that you are not experiencing any other health problems.

Can low vitamin D cause Gray hair?

There is no scientific evidence to support the claim that low vitamin D levels can cause grey hair. However, vitamin D is necessary for healthy hair growth. So, if you are not getting enough vitamin D, you may experience other problems such as dry, brittle hair.

Do I need to take a vitamin D supplement?

If you are not getting enough vitamin D from sunlight or your diet, you may need to take a supplement. Vitamin D supplements are available in both capsule and liquid form. Be sure to talk to your doctor before taking any supplements, as they can interact with other medications you may be taking.

Final Thoughts

There are many benefits of vitamin D, but it’s important to get the right amount. Too much or too little vitamin D can be harmful. Be sure to talk to your doctor about whether you should take a supplement. And, get out in the sun when you can to soak up some of this essential vitamin!

Vitamin D is an essential nutrient that offers many health benefits. If you are not getting enough vitamin D, be sure to talk to your doctor about taking a supplement. Getting enough vitamin D can help improve your overall health and well-being.

Benefits, Sources, Deficiency And Risks – Forbes Health

Also known as the “sunshine vitamin,” vitamin D is an essential nutrient available through sun exposure, dietary sources and supplementation. This vitamin plays a key role in many aspects of health, including bone health, immune function and more.

Still, many people are missing out, with some research estimating that nearly 48% of the global population has below-adequate blood levels of vitamin D ^{tippy-popover-container-bg-white’ }”>[1]}Cui A, et al. Global and Regional Prevalence of Vitamin D Deficiency in Population-Based Studies From 2000 to 2022: A Pooled Analysis of 7.9 Million Participants. Front Nutr. 2023;10:1070808. . Vitamin D3 supplements can be a safe and convenient option to help you meet your needs, especially if you’re at risk of an insufficiency or deficiency.

In this article, we cover how vitamin D3 can benefit your health, how you can meet your needs and the potential safety concerns and side effects of supplementation.

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Vitamin D2 vs Vitamin D3

Vitamin D is found in two different forms; ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3), each of which differs slightly in terms of chemical structure. “Vitamin D3 is obtained from animal sources, whereas vitamin D2 is mainly from fungal sources,” explains John White, Ph.D., chair of the department of physiology at McGill University in Montreal and a molecular biologist who has conducted extensive research on vitamin D.

Though both forms are well-absorbed in the gut, vitamin D3 may be a better choice for supplementation. According to one small study, vitamin D3 could actually be more effective at increasing vitamin D levels in the blood than vitamin D2^[2]Shieh A, et al. Effects of High-Dose Vitamin D2 Versus D3 on Total and Free 25-Hydroxyvitamin D and Markers of Calcium Balance. J Clin Endocrinol Metab. 2016 ;101(8):3070-8. . On the other hand, Dr. White notes that vitamin D2 may be a better choice if you’re following a vegan diet, as vitamin D3 supplements are often derived from animal sources.

Benefits of Vitamin D3

Maintaining adequate levels of vitamin D may offer several potential benefits:

Enhances Bone Health

“Vitamin D3 is essential for the absorption and utilization of calcium and phosphorus, which are vital for maintaining strong and healthy bones,” says Sam Schleiger, a functional medicine dietitian and founder of Simply Nourished, a nutrition practice in Elkhorn, Wisconsin.

Vitamin D is also needed to support bone growth and for bone remodeling, a bodily process which involves the removal of old bone tissue from the skeleton and the formation of new bone tissue. “A profound vitamin D deficiency leads to rickets [a softening and weakening of bones] in children and osteomalacia, or soft bone, in adults because there’s not enough calcium in the bone,” notes Dr. White.

Promotes Immune Function

Vitamin D is essential for immune health and disease prevention. In fact, some research suggests vitamin D deficiency could worsen or increase the incidence of certain autoimmune conditions, such as rheumatoid arthritis ^{tippy-popover-container-bg-white’ }”>[3]}Ao T, et al. The Effects of Vitamin D on Immune System and Inflammatory Diseases. Biomolecules. 2021;11(11):1624. . “There is also evidence that maintaining vitamin D sufficiency reduces the long-term risk of developing certain types of cancer,” adds Dr. White.

According to one review, vitamin D supplementation could be associated with a reduced risk of certain infections, including influenza and COVID-19^[4]Grant WB, et al. Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths. Nutrients. 2020;12(4):988. . What’s more, another study shows that having low levels of vitamin D could even be tied to a greater risk of multiple sclerosis ^{tippy-popover-container-bg-white’ }”>[5]}Sintzel MB, et al. Vitamin D and Multiple Sclerosis: A Comprehensive Review. Neurol Ther. 2018;7(1):59-85. .

May Support Weight Management

Some research suggests that obesity may be associated with low vitamin D levels. It’s also believed that vitamin D could influence body weight by regulating the growth of fat cells and altering the expression of certain genes and the levels of hormones that affect hunger, such as leptin^[6]Karampela I, et al. Vitamin D and Obesity: Current Evidence and Controversies. Curr Obes Rep. 2021;10(2):162-180. .

While more research is needed, one very small study found pairing vitamin D supplementation with a weight loss diet resulted in greater weight loss and fat loss than following a weight loss diet alone ^{tippy-popover-container-bg-white’ }”>[7]}Lotfi-Dizaji L, et al. Effect of Vitamin D Supplementation Along With Weight Loss Diet on Meta-Inflammation and Fat Mass in Obese Subjects With Vitamin D Deficiency: A Double-Blind Placebo-Controlled Randomized Clinical Trial. Clin Endocrinol (Oxf) . 2019 ;90(1):94-101. .

Regulates Mood

“Vitamin D3 is involved in the production and regulation of neurotransmitters like serotonin, which is important for mood regulation,” says Schleiger. “Adequate vitamin D3 levels may help improve mood and overall mental well-being.”

Interestingly, a review of 25 studies concluded vitamin D supplementation could reduce negative emotions, especially for people with major depressive disorder or a vitamin D deficiency^[8]Cheng Y-C, et al. The Effect of Vitamin D Supplement on Negative Emotions: A Systematic Review and Meta-Analysis. Depress Anxiety. 2020 Jun;37(6):549-564. . What’s more, other research suggests low levels of vitamin D could be associated with increased symptoms of depression and anxiety^[9]Akpınar S, et al. Is Vitamin D Important in Anxiety or Depression? What Is the Truth?. Curr Nutr Rep. 2022;11(4):675-681. .

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Sources of Vitamin D3

Vitamin D3 is found naturally in several food sources, including fatty fish and fish liver oils. Other animal products like egg yolks, cheese and beef liver also contain a small amount of vitamin D3 in each serving.

Here are a few food sources of vitamin D3 and the percentage of the Daily Value (DV) that they provide, according to the National Institutes of Health^[10]Vitamin D. National Institutes of Health. Accessed 05/17/2023. :

Cod liver oil	1 tablespoon	1,360 International Units	170%
Rainbow trout, cooked	3 ounces	645 International Units	81%
Sockeye salmon, cooked	3 ounces	570 International Units	71%
Egg, scrambled	1 large	44 International Units	6%
Beef liver, braised	3 ounces	42 International Units	5%
Tuna, canned in water	3 ounces	40 International Units	5%
Cheddar cheese	1. 5 ounces	17 International Units	2%

Can You Get Vitamin D3 From the Sun?

Though vitamin D3 is available in supplements and several food sources, you can also meet your needs by getting regular sun exposure. This is because the skin produces vitamin D when exposed to ultraviolet rays from the sun.

However, you don’t need to sunbathe to meet your vitamin D needs (and protecting yourself from the sun is still important to decrease the risk of skin cancer). As long as the temperature outside is above 45 degrees fahrenheit, 20 minutes or so of sun exposure on the face and arms is generally enough to produce enough vitamin D in your skin to maintain vitamin D sufficiency, notes Dr. White.

Keep in mind certain factors can affect how much sunlight you need to meet your vitamin D needs, including your skin pigmentation and age. Your location and the season and time of day can also impact how much vitamin D your skin produces.

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Vitamin D3 Precautions

It’s best to talk to your doctor before starting supplementation, especially if you’re taking other medications or have any underlying health conditions. According to Schleiger, vitamin D supplements may interact with certain medications, including corticosteroids and medications for seizures or high cholesterol. She also adds that high-dose supplements might not be suitable for people with specific health conditions, such as hyperparathyroidism, sarcoidosis or kidney disease.

While it’s possible to consume too much vitamin D3, it’s rare. “Vitamin D toxicity from supplementation exists but you have to try really, really, really hard,” says Dr. White. “For example, there are clinical trials where patients are given 100,000 to even 600,000 IUs (International Units) in bolus doses without side effects.”

Still, taking extremely high doses of vitamin D for an extended period can cause vitamin D toxicity, which can lead to elevated levels of calcium in the blood, Schleiger explains. “[This] can cause symptoms such as nausea, vomiting, constipation, weakness, excessive thirst, frequent urination and, in severe cases, kidney stones or organ damage,” she says.

The upper tolerable limit for supplementation is 4,000 International Units per day, according to Dr. White. And while he does note that this amount is most likely conservative, 4,000IU is still more than most people need to take.

“Following the recommended dosage guidelines and regular monitoring of vitamin D levels through blood tests can help ensure safe and effective supplementation,” says Schleiger.

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DeTriFerol. An easy way to get the norm of vitamin D3

International nonproprietary name:

cholecalciferol

Composition:

1 ml of the drug contains:

Active ingredient:

Cholecalciferol

90 004

15000 IU (0. 375 mg)

Excipients:

Propylene glycol

100 mg

Macrogol glyceryl hydroxystearate

50 mg

Methyl parahydroxybenzoate

1.0 mg

Sodium saccharinate

0.7 mg

Anise, banana, cherry flavor yellow or orange

0.7 mg

Sodium hydrogen phosphate dihydrate

3.0 mg

Anhydrous citric acid

0.6 mg

Water for injection

up to 1.0 ml

Pharmacotherapeutic group :

vitamin D and its analogues.

Indications for use

Prevention of vitamin D deficiency and diseases associated with its deficiency (rickets, osteomalacia).

Treatment of rickets.

Complex therapy of osteoporosis of various origins.

Contraindications

Hypersensitivity to cholecalciferol and/or to any of the excipients in the formulation.

Vitamin D hypervitaminosis.

Increased blood calcium concentration (hypercalcemia), increased excretion of calcium in the urine (hypercalciuria), urolithiasis (formation of calcium oxalate stones), renal osteodystrophy with hyperphosphatemia, pseudohypoparathyroidism.

Sarcoidosis.

Acute and chronic diseases of the liver and kidneys, renal failure.

Active form of pulmonary tuberculosis.

Children under 4 weeks of age. Use during pregnancy and lactation overdose.

Vitamin D3 should be used with caution in women who are breastfeeding, because the drug taken in high doses by the mother can cause symptoms of overdose in the child.

In the case of the use of the drug during pregnancy and during breastfeeding, it is necessary to take into account the intake of vitamin D from other sources, the daily dose of vitamin D should not exceed 600 IU.

Directions for use

Orally.

Take the drug in a spoonful of liquid.

1 drop contains about 500 IU of vitamin D3.

Prevention of rickets:
Full-term newborns from 4 weeks of age – 1 drop (500 IU) per day;

Premature babies from 4 weeks of age – 2 drops (1000 IU) per day during the first year of life, then 1 drop (500 IU) per day. The drug should be used during the first two years of a child’s life, during periods of low insolation (especially in winter).

Treatment of rickets:
In the absence of visible deformities of the skeletal system (mild degree of rickets) – 2-3 drops (1000-1500 IU) per day, continue treatment for 30 days.

In the presence of deformities of the skeletal system characteristic of moderate and severe rickets – 4-8 drops (2000-4000 IU) per day, continue treatment for 30-45 days, the dose of the drug and the duration of therapy depend on the severity of the changes and are determined doctor (see section “Special Instructions”).

Prevention of vitamin D deficiency and diseases associated with its deficiency (osteomalacia):
1 drop (500 IU) per day during the entire period accompanied by vitamin D deficiency. The minimum duration of the course of prevention is 1 month.

Shelf life

3 years. Do not use after the expiration date!

Terms of sale

Available without a prescription.

Registration certificate holder

OOO Grotex

Russia, 195279, St. Petersburg Industrialny pr., 71, building 2, lit. A

Tel.: +7 812 385 47 87
Fax: +7 812 385 47 88

, St. Petersburg Industrialny pr., 71, building 2, lit. A

Tel.: +7 812 385 47 87
Fax: +7 812 385 47 88

www.solopharm.com
www.detriferol.ru

Registration number: LP-005163 900 05 Complete instructions for use

benefits and effects on the body

03/04/2021

5-7 minutes

143 881

Contents

• The sunniest and most needed: why does the body need vitamin D?
• Such different vitamin D
• Helper of the body: the role of vitamin D in the absorption of calcium
• Why is vitamin D needed ₃ in the body?
• Not just for bones: what is the benefit of vitamin D for the body?
• Only girls in jazz: the impact of vitamin D on women’s health
• Especially for Men: The Importance of Vitamin D in Men’s Health
• Actively Seeking: Sources of Vitamin D
• To each according to his needs: how much vitamin D does a person need?
• How can I check my vitamin D level?
• I feel that something is missing: vitamin D deficiency
• More is not better: too much vitamin D
• Office hours: how to take vitamin D correctly?
• What are the side effects of vitamin D?
• How long can I take vitamin D ₃ ?

Vitamin D has been “in” for a long time. And during the pandemic, when people began to look for the most effective substances to strengthen immunity, it became even more popular. Why is vitamin D so necessary and does it have contraindications? Why is vitamin D3 needed and what benefits does it have for the body? Let’s get to know him better and find out all the most important things about him.

Such miscellaneous vitamin D

Vitamin D is found naturally only in a very limited amount of food, and synthesis in the human body is possible only under certain conditions, when the ultraviolet rays of sunlight hit the skin.

There are several varieties of vitamin D. The most important are D ₂ (ergocalciferol) isolated from yeast and D ₃ (cholecalciferol) of animal origin.

Body helper: the role of vitamin D in calcium absorption

Vitamin D, obtained from food and supplements, and formed during exposure to the sun, is biologically inert. Its activation and transformation into an active form occurs in the liver and kidneys.

The vitamin is of great importance in the proper development of the body, in particular, it helps to absorb calcium and maintain healthy bones *

To learn more

Vitamin D is needed to prevent the development of osteoporosis, rickets, spinal deformity, and this substance also plays an important role in the formation of proper posture, bone tissue and metabolism.

Of course, calcium can be obtained from the same fermented milk products, but without vitamin D, it will be absorbed much worse.

The optimal balance of the ratio of calcium and vitamin D can be found in Calcium-D3 Nycomed.

Taking two tablets a day, the body receives the daily requirement of calcium, as well as vitamin D ₃ which helps calcium to be absorbed.

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The drug also has a Forte form, it contains an increased dosage of vitamin D ₃

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More than just bones: what are the health benefits of vitamin D?

Vitamin D regulates the absorption of calcium and phosphorus – together with these minerals and vitamin A, they form the basis of defense for our immunity, are responsible for the health of muscles, bones, protect against colds and many diseases.

Vitamin D ₃ is synthesized in several stages in the human body and has such a strong effect on the endocrine system that it is called a hormone!**

Useful properties of vitamin D *

Studies show that vitamin D ₃ is able to regulate the functioning of the gastrointestinal tract and be used in the treatment of symptoms of irritable bowel syndrome***.

Only girls in jazz: the impact of vitamin D on women’s health

Vitamin D helps the fetus develop properly during pregnancy, helps to recover after childbirth and various surgical interventions. Supports the functioning of the body and improves the quality of life during menopause.

With the onset of menopause, the risk of developing osteoporosis also increases, and without calcium, the body cannot cope with vitamin D!

Especially for men: the importance of vitamin D in maintaining men’s health

For men, vitamin D is not only a support for the musculoskeletal system, but also an assistant in maintaining reproductive functions. Together with calcium, vitamin D maintains testosterone levels, regulates the amount of estrogen (female sex hormone), and reduces the risk of infertility. What else is vitamin D3 useful for: it prevents prostate diseases and fights obesity**.

For athletes, vitamin D helps build muscle, increase stamina, stay active, and maintain joint mobility and bone health*****.

For information

According to some researchers, the functions of vitamin D are not limited to the control of calcium-phosphorus metabolism, it also affects other physiological processes in the body, including the modulation of cell growth, neuromuscular conduction, immunity and inflammation.

Actively looking for sources of vitamin D

The intake of vitamin D in our body occurs under the influence of ultraviolet radiation, for which the skin is responsible. Sunbathing, we ensure the strengthening of immunity, but not everything is so simple. Closed clothing and the use of sunscreen reduce the synthesis of the vitamin, and some people absolutely should not be in the open sun.

In winter, to receive a dose of 1000 ME, a person needs to spend about 130 minutes in the sun at the peak of activity at noon, provided that 10% of exposed skin is under the rays. In summer, 10 minutes at noon with 25% skin exposure is sufficient. Scientists have calculated this rate to reduce the likelihood of getting a sunburn ******.

To each according to his needs: how much vitamin D does a person need?

Prevention of vitamin D deficiency will depend on the age and individual characteristics of the individual. Usually for adults (from 18 to 50 years old) the daily dose is 600-800 IU, for pregnant women and people over 50-60 years old – from 800 to 1000-1200 IU ***.

Only a doctor can determine the exact need, as well as find out the presence of individual contraindications.

How can I check my vitamin D level?

With the help of a blood test, you can find out the level of vitamin D, which will allow the doctor to correctly select the dosage of the drug in case of its deficiency or the appropriate antagonist substance in case of an excess.

No special preparation is needed for a laboratory test, it is enough to go to the laboratory in the morning and donate blood serum.

I feel something is missing: vitamin D deficiency

Many symptoms indicate a vitamin D deficiency. This can be expressed both in obvious diseases of the organs, and in a mental state (for example, with depression or anxiety), vitamin D can also help here.

The following most often indicate an active deficiency of the “sunshine” vitamin*:

weakness

loss of appetite

brittle bones

muscle weakness

decreased mood, apathy, irritability

frequent colds and other illnesses

problems with teeth, frequent caries, loosening

weight change

insomnia

impaired concentration

vision problems

skin deterioration

menstrual disorders

metabolic disorders

deformity of posture

problems with the uterus and ovaries

hypertension, arthritis, diabetes, atherosclerosis, etc.

Indications for vitamin D intake are the presence of symptoms and an analytically confirmed micronutrient deficiency.

Bigger is not better: too much vitamin D

Hypervitaminosis, or too much vitamin D in the body, can also be harmful. The maximum dosage for a person is 4000 IU ****.

Excessive vitamin intake can cause many problems. Vitamin D ₃ in high doses has the following side effects:

nausea

convulsions

sudden increase or decrease in blood pressure

frequent urination

irregular heart rhythm, rapid heart palpitations, arrhythmia

emotional instability

skin pallor

sleep disturbance

constipation or diarrhea

fever

headache and muscle pain

demineralization of bone tissue, stones on the teeth

loss of appetite

deposition of calcium salts in organs

Side effects can be either a manifestation of individual intolerance or an overdose. The correct therapeutic dosage can only be prescribed by a doctor after a blood test.

Office hours: how to take vitamin D correctly?

It is believed that it is correct to take vitamin D in the morning – at this time it is better absorbed by the body and does not interfere with getting ready for bed*******. In the evening, it will be more difficult to cope with such a strong energy flow, so insomnia and overexcitation are likely.

Vitamin D has the following contraindications:

• excess calcium (hypercalcemia)
• hypervitaminosis D
• hypersensitivity
• endocrine and metabolic diseases
• renal osteodystrophy, severe insufficiency
• kidney stones
• bone metastases and various neoplastic diseases
• idiosyncrasy

What are the side effects of vitamin D?

It all depends on the individual characteristics of the body and the dosage that must be selected with the attending physician.