What does albuterol do for bronchitis? What are the different types of inhalers and nebulizers used to treat bronchitis? Learn about the various medications and how they can help with your respiratory symptoms.

Understanding Bronchitis and Inhaled Treatments

Bronchitis is a respiratory condition characterized by inflammation and irritation of the bronchial tubes, which can lead to coughing, chest soreness, and fatigue. While acute bronchitis typically resolves on its own, chronic or severe cases may require additional medical interventions. One such approach is the use of inhaled medications, including inhalers and nebulizers, which can help manage the symptoms and underlying conditions associated with bronchitis.

Types of Inhalers for Bronchitis

Inhalers are a common method of delivering medications directly to the lungs, where they can provide targeted relief for respiratory conditions like bronchitis. Doctors may prescribe various types of inhaler medications for the management of bronchitis, including:

Beta-2 Agonists

Short-acting beta-2 agonists, such as albuterol and salbutamol, are commonly used to treat the symptoms of bronchitis, including severe coughing and wheezing. These medications work by relaxing the airway passages, making it easier to breathe.

Inhaled Corticosteroids

Inhaled corticosteroids, like beclomethasone, budesonide, and fluticasone, help reduce airway inflammation, which can be beneficial for individuals with bronchitis, as the lungs are often already irritated from an upper respiratory infection.

Long-Acting Beta-2 Agonists (LABAs)

LABAs, such as arformoterol tartrate and formoterol fumarate, are similar to short-acting beta-2 agonists but are designed to provide long-lasting relief from wheezing and other respiratory symptoms. Doctors often prescribe LABAs in combination with inhaled corticosteroids.

Nebulizer Treatments for Bronchitis

Nebulizers are another form of inhaled medication delivery, which use an air compressor to convert liquid medications into a fine mist that is then inhaled. Nebulizer treatments are often prescribed for children or individuals who may have difficulty using traditional inhalers effectively. Nebulized medications used for bronchitis may include:

Long-Acting Beta-2 Agonists (LABAs)

The same LABA medications used in inhalers, such as arformoterol tartrate and formoterol fumarate, can also be delivered through a nebulizer.

Long-Acting Muscarinic Agents (LAMAs)

LAMAs, like umeclidinium and tiotropium, work on different receptors in the lungs compared to beta-agonists, helping to further open up the airways and improve breathing.

Short-Acting Beta-Agonists (SABAs)

Albuterol, a common SABA medication, can be administered through a nebulizer to provide acute relief for wheezing and other respiratory symptoms during a bronchitis flare-up.

Short-Acting Muscarinic Antagonists (SAMAs)

Medications like ipratropium bromide (Atrovent) are SAMAs that can be used in nebulizers to treat chronic bronchitis and COPD.

Combining Inhaled Medications

Many of these inhaled medications are available in combination formulations, such as SABA-SAMA or LABA-LAMA, to provide more comprehensive treatment for individuals with respiratory conditions like bronchitis.

Steam and Humidified Air Therapy

In addition to inhaled medications, some people with bronchitis may find relief by incorporating warm, humidified air into their treatment regimen. This can be achieved through various methods, such as:

• Inhaling steam from a bowl of boiling water, with a towel draped over the head to contain the steam
• Taking a hot shower
• Using a humidifier in the room, ensuring proper cleaning and maintenance

The warm, moist air can help soothe the irritated airways and potentially reduce coughing associated with bronchitis.

Choosing the Right Inhaled Therapy for Bronchitis

The choice of inhaled medication and delivery method, whether it’s an inhaler or a nebulizer, will depend on the individual’s specific needs, age, and underlying respiratory conditions. It’s important to work closely with a healthcare provider to determine the most appropriate treatment plan for effectively managing bronchitis and its associated symptoms.

Types of Inhalers and Nebulizers

Just when you think you’ve gotten over that respiratory infection, bronchitis hits. The coughing, chest soreness, and fatigue can really get you down.

While acute bronchitis will usually go away without prescription treatments, chronic or an especially nasty case of acute bronchitis may require some extra help.

We explain inhaled treatments for bronchitis, including nebulizer and inhaler treatments, and how they may help.

Inhalers are medications that are delivered through the mouth and to the lungs.

Usually this is a device with a short mouthpiece that connects to a small canister you press down on. When you press down and inhale, the medication enters your mouth and goes down into your lungs.

A doctor may prescribe a few different types of inhaler medications for bronchitis. These include the following:

Beta-2 agonists

Some of the most common inhaler medications are short-acting beta-2 agonists. These include medications like albuterol and salbutamol.

Doctors prescribe beta-2 agonists to treat:

• asthma
• chronic obstructive pulmonary disease (COPD)
• severe coughing that can come with acute bronchitis

These medications work by relaxing airway passages in the lungs, which can make it easier to breathe.

The Cochrane Database of Systematic Reviews analyzed the results of five different studies of beta-2 agonists as a treatment for acute bronchitis in adults.

They concluded that there’s little evidence to support the use of beta-2 agonists in adults with acute bronchitis.

However, they did find that inhalers helped people who tended to wheeze frequently, even when they weren’t sick.

Inhaled corticosteroids

Inhaled corticosteroids help to reduce airway inflammation. This can be helpful when you have bronchitis, because it’s usually after an upper respiratory infection and your lungs are already very irritated.

These medications won’t relieve a wheezing attack immediately, but they can help to reduce:

• airway swelling
• excess mucus
• tight airways

Examples of inhaled corticosteroids doctors prescribe include:

• beclomethasone
• budesonide
• fluticasone

Long-acting beta-2 agonists (LABAs)

These medications are similar to short-acting beta-2 agonists like albuterol. They aren’t meant for acute attacks of wheezing, but rather reduce the risk of wheezing all day.

Examples of LABAs include arformoterol tartrate (Brovana) and formoterol fumarate (Oxeze, Foradil).

Doctors usually prescribe these with inhaled corticosteroids.

Nebulizer treatments are another form of inhaled medications. Instead of a short mouthpiece, nebulizer treatments usually have a longer mouthpiece and an air compressor that helps convert the medication to a fine mist.

Doctors often prescribe nebulizers to children who may have a harder time using an inhaler properly.

Instead of having to time the pumps to breathe medication in, a person just takes deep breaths in and out to take in the medication.

Nebulizers are also useful for people who may require larger amounts of inhaled medications, such as those for:

• acute asthma attacks
• pneumonia
• COPD

A doctor would usually prescribe nebulized medications to treat acute bronchitis in children or for chronic bronchitis in adults.

Examples of nebulized medications include:

• Long-acting beta-2 agonists (LABAs). These medications are usually the same as those available for inhalers.
• Long-acting muscarinic agents (LAMAs). These medications work on different receptors in the lungs than beta-agonists to help open up the airways so you can breathe better. Examples of these medicines include umeclinium (Ellipta) and tiotropium (HandiHaler, Respimat).
• Short-acting beta-agonists (SABAs). Like with traditional inhalers, a person can use albuterol in a nebulizer. These are mostly for acute attacks in bronchitis, such as wheezing.
• Short-acting muscarinic antagonists (SAMAs). These are medications like ipratropium bromide (Atrovent). Doctors prescribe them to treat chronic bronchitis and COPD.

Many of these medications are available in combination, such as SABA-SAMA or LABA-LAMA.

Nebulized medications may not be as good a fit for adults without COPD, because nebulizers require special equipment and teaching to use.

Ideally, a person with acute bronchitis wouldn’t need this type of equipment.

In addition to nebulizers and inhalers, some people may inhale warm, humidified air (steam) at home to improve their breathing.

Sometimes cold air can irritate the lungs and worsen coughing when you have bronchitis. Warm, moist air may help you feel better and reduce coughing.

Here are some ways you can incorporate steam or mist therapy into your bronchitis treatments:

• inhale steam from a bowl of boiling water, while hovering at least 8 to 12 inches away with a towel over your head to hold the steam in
• take a hot shower
• use a humidifier in your room, but be sure to carefully clean it after use

Many drugstores also sell plugin steam inhalers.

The side effects from inhalers and nebulizer treatments depend upon the type used. Examples of side effects include the following:

• Beta-2 agonists may cause tremors, nervousness, and shakiness.
• Corticosteroids can causesore mouth, cough, hoarse voice, or nosebleeds. Oral thrush can develop if a person doesn’t rinse their mouth out after use.
• LABAs can cause heart palpitations and tremors.
• LAMAs may cause constipation, dry mouth, and urinary retention.

If you experience any of these when you use an inhaler or nebulizer, talk to your doctor about ways to minimize these side effects. You can also find out if other medications are available.

They may suggest using a spacer device, which maximizes the delivery of the medication to the lungs. This minimizes the settling of medication to the back of the throat, which can lead to side effects.

With treatment and rest, you’ll ideally recover within about 1 to 2 weeks. It may take a bit longer for some people.

If your symptoms, especially your cough, persist beyond 3 weeks, consider scheduling another appointment with your doctor.

A doctor can evaluate you for other potential coughing causes, such as:

• asthma
• sinusitis
• COPD
• gastroesophageal reflux disease (GERD)
• heart failure
• pulmonary embolism

According to StatPearls, doctors may misdiagnose as many as one-third of patients with bronchitis when the patients actually have asthma.

You should talk with a doctor if you have a cough that persists after an upper respiratory infection, and it keeps you from completing everyday activities or starts to make your chest hurt.

If you have a fever that accompanies your symptoms, your infection may be bacterial. A doctor can prescribe antibiotics that can help bronchitis go away.

If your cough persists after 3 weeks, you may need to make another appointment with your doctor. Bronchitis will usually subside by this time, so you could have another medical condition.

Sometimes, bronchitis can lead to pneumonia. This is a severe lung infection.

Seek emergency medical treatment if you have worsening symptoms like:

• shortness of breath
• blue-tinted lips or fingernails
• confusion

Doctors usually treat bronchitis by treating its symptoms.

If your symptoms include wheezing and coughing, your doctor may prescribe an inhaler or nebulizer. These may help you manage your symptoms until you start feeling better.

How Albuterol Inhalers Can Help Treat Bronchitis at Nao Medical

Are you struggling with bronchitis and looking for a solution? Look no further than Nao Medical! Our team of healthcare professionals is dedicated to providing you with the best possible care and treatment options, including the use of albuterol inhalers.

What is Bronchitis?

Bronchitis is a respiratory condition that occurs when the bronchial tubes become inflamed and produce excess mucus. This can lead to coughing, wheezing, and difficulty breathing. Bronchitis can be acute or chronic, with acute bronchitis typically lasting for a few weeks and chronic bronchitis lasting for several months or more.

How Can Albuterol Inhalers Help?

Albuterol inhalers are a type of bronchodilator that work by relaxing the muscles in the airways, making it easier to breathe. They are often used to treat asthma, but can also be effective in treating bronchitis. Albuterol inhalers can help relieve symptoms such as coughing, wheezing, and shortness of breath, making it easier to get through the day.

Why Choose Nao Medical?

At Nao Medical, we are committed to providing our patients with the best possible care and treatment options. Our team of healthcare professionals is highly trained and experienced in treating a wide range of respiratory conditions, including bronchitis. We offer same-day appointments, minimal wait times, and exceptional and empathetic staff to ensure that you receive the care you need when you need it.

In addition to albuterol inhalers, we offer a range of other treatment options for bronchitis, including antibiotics, cough suppressants, and anti-inflammatory medications. We also offer virtual care options for after-hours appointments, so you can get the care you need from the comfort of your own home.

Book an Appointment Today

If you are struggling with bronchitis, don’t suffer in silence. Book an appointment with Nao Medical today to learn more about how albuterol inhalers and other treatment options can help relieve your symptoms and improve your quality of life. Our team is here to help you breathe easy!

Frequently Asked Questions

What is an albuterol inhaler?

An albuterol inhaler is a type of bronchodilator that works by relaxing the muscles in the airways, making it easier to breathe. It is often used to treat asthma, but can also be effective in treating bronchitis.

How do I use an albuterol inhaler?

Albuterol inhalers are typically used as needed to relieve symptoms such as coughing, wheezing, and shortness of breath. To use an albuterol inhaler, remove the cap and shake the inhaler well. Breathe out fully, then place the inhaler in your mouth and press down on the canister to release the medication. Breathe in slowly and deeply, then hold your breath for a few seconds before exhaling.

What are the side effects of using an albuterol inhaler?

Common side effects of using an albuterol inhaler include shaking, nervousness, headache, and increased heart rate. These side effects are usually mild and go away on their own, but if you experience any severe or persistent side effects, be sure to contact your healthcare provider.

Can I use an albuterol inhaler if I have other medical conditions?

Albuterol inhalers are generally safe for most people to use, but if you have other medical conditions such as heart disease or high blood pressure, be sure to talk to your healthcare provider before using an albuterol inhaler.

How can I prevent bronchitis?

There are several steps you can take to help prevent bronchitis, including washing your hands frequently, avoiding close contact with people who are sick, and quitting smoking if you are a smoker. It is also important to stay up-to-date on your vaccinations, as certain respiratory infections can increase your risk of developing bronchitis.

External Links:

• https://www.cancer.gov/publications/dictionaries/cancer-terms/def/pulmonology
• https://www.lung.org/

Disclaimer: The information presented in this article is intended for general informational purposes only and should not be considered, construed or interpreted as legal or professional advice, guidance or opinion.

Salbutamol dosed aerosol for inhalation GlaxoSmithKline Export

• Pharmacological properties
• Indications Salbutamol
• Application Salbutamol
• Contraindications
• Side effects
• Special instructions
• Interactions
• Overdose
• Storage conditions
• Diagnosis
• Recommended alternatives
• Trade names

pharmacodynamics . Salbutamol is a selective agonist of β ₂ -adrenergic receptors. In therapeutic doses, it acts on β ₂ -adrenergic receptors of bronchial smooth muscles, providing fast (within 5 minutes) and short-term (4-6 hours) bronchodilation in patients with reversible airway obstruction.

Pharmacokinetics . After inhalation, 10 to 20% of the administered dose reaches the lower respiratory tract. The rest of it is retained in the inhalation device or in the nasopharynx, from where it is swallowed. Part of the dose that has reached the respiratory tract is absorbed into the lung tissue and enters the bloodstream, but is not metabolized in the lungs.

After entering the systemic circulation, the drug is metabolized in the liver, excreted mainly by the kidneys in unchanged form and as a phenol sulfate metabolite.

The dose of the drug, which has entered the digestive system from the nasopharynx, is absorbed in the gastrointestinal tract, undergoes the first stage of metabolism in the liver to the phenol sulfate compound, and then is excreted by the kidneys. Most of the drug is excreted from the body within 72 hours. Plasma protein binding is 10%.

transient (4 to 6 hours) bronchodilation with rapid onset (within approximately 5 minutes) in airway obstruction.

Relief of asthma attacks in diseases accompanied by airway obstruction, such as asthma.

Prevention of attacks of bronchospasm associated with exposure to an allergen or caused by exercise.

In the complex therapy of patients with BA.

Salbutamol is an aerosol intended for inhalation by mouth only. For patients who find it difficult to synchronize breathing with the use of an inhaler, it is recommended to additionally use a spacer – a device to facilitate the inhalation of inhaled drugs.

Adults (including elderly patients)

For relief of exacerbation of asthma symptoms, including acute bronchospasm, 1 inhalation (100 mcg) can be used as the minimum starting dose. If necessary, the dose can be increased to 200 mcg (2 inhalations).

200 mcg (2 inhalations) as a prophylactic 10-15 minutes before physical activity or anticipated exposure to allergens.

For long-term maintenance therapy, it is recommended to use 200 mcg (2 inhalations) 4 times a day. The total daily dose of salbutamol should not exceed 800 micrograms (8 inhalations).

In children over 12 years of age, use the same dose as for adults.

Children aged 4 to 12 years

For the relief of acute bronchospasm, use 1 inhalation (100 mcg). If necessary, the dose can be increased to 200 mcg (2 inhalations).

100 mcg (1 inhalation) is used prophylactically 10-15 minutes before physical activity or expected exposure to allergens, if necessary, the dose can be increased to 200 mcg (2 inhalations).

For long-term maintenance therapy, it is recommended to use 200 mcg (2 inhalations) 4 times a day. The total daily dose of salbutamol should not exceed 800 micrograms (8 inhalations).

An increased need for agonists of β ₂ -adrenergic receptors may indicate a worsening of the course of asthma. Under these conditions, the patient’s treatment regimen should be reviewed and the need for GCS therapy should be considered.

Inhaler instructions for use

Checking the inhaler

Before using the inhaler for the first time or after a break in use of 5 days or more, remove the cap of the mouthpiece by gently pressing it on the sides, shake the inhaler well and make 2 sprays into the air to make sure it works adequately.

Using the inhaler

1. Remove the mouthpiece cap by lightly pressing on the sides.

2. Make sure that there are no foreign objects inside and outside the inhaler, including the mouthpiece.

3. Shake the inhaler thoroughly to remove any foreign object from the inhaler and mix the contents evenly.

4. Hold the inhaler in your hand vertically between your thumb and fingers, with your thumb on the body of the inhaler below the mouthpiece.

5. Exhale as deeply as possible, then take the mouthpiece between your teeth and place your lips around it without biting.

6. While inhaling through the mouth, depress the tip of the inhaler to spray salbutamol while continuing to inhale slowly and deeply. One click on the top of the inhaler corresponds to one dose.

7. Hold your breath, remove the inhaler from your mouth and remove your finger from the top of the inhaler. Continue to hold your breath for as long as possible.

8. If further sprays are required, wait approximately 30 seconds while holding the inhaler upright. After that, follow the steps described in points 3-7.

9. Replace the mouthpiece cap by pushing in the desired direction until it clicks into place.

Important :

do the steps in points 5, 6 and 7 slowly. Before spraying, you need to inhale as slowly as possible. The first few times you should practice in front of a mirror. If a “cloud” appears at the top of the inhaler or on the sides of the mouth, you must start the procedure again from point 2.

If your doctor has given you other instructions for using your inhaler, follow them and seek advice if you have any difficulty.

Children . Young children may need help, and it may be necessary for adults to inhale them. Ask the child to exhale and spray as soon as he begins to inhale. It is recommended to master the technique together. Children or debilitated adults can hold the inhaler with both hands. Place both index fingers on the top of the inhaler and both thumbs on the base below the mouthpiece.

Cleaning

The inhaler should be cleaned at least once a week.

1. Remove the metal canister from the plastic case of the inhaler and remove the mouthpiece cap.

2. Rinse the plastic case and mouthpiece cap with warm water.

3. Dry them inside and out.

4. Replace the metal bottle and mouthpiece cap.

Do not immerse the metal can in water.

history of hypersensitivity to the components of the drug. Do not use salbutamol dosage forms that are not intended for intravenous administration to suspend uncomplicated preterm labor or threatened abortion.

The following side effects are classified by organs and systems, as well as by frequency of occurrence: very often (≥1/10), often (≥1/100 and <1/10), infrequently (≥1/1000 and <1/ 100), rarely (≥1/10,000 and <1/1000), very rare (<1/10,000), including isolated cases, the frequency is unknown.

From the immune system : very rarely – hypersensitivity reactions, including angioedema, urticaria, bronchospasm, arterial hypotension and collapse.

From the side of metabolism, metabolism : rarely: hypokalemia. Potentially, the use of β ₂ -adrenergic receptor agonists can cause severe hypokalemia.

Neurological disorders: often – tremor, headache; very rarely – hyperactivity.

Cardiac disorders: often – tachycardia; infrequently – increased heartbeat; very rarely: cardiac arrhythmia, including atrial fibrillation, supraventricular tachycardia and extrasystole; frequency unknown: myocardial ischemia (see SPECIAL INSTRUCTIONS).

Vascular disorders: rare: peripheral vasodilation.

On the part of the respiratory system, chest organs and mediastinum : very rarely – paradoxical bronchospasm.

Gastrointestinal disorders: infrequently – irritation of the mucous membranes of the oral cavity and pharynx.

From the musculoskeletal system and connective tissue: infrequently – muscle cramps.

In order to optimally get the drug into the lungs of the patient, it is necessary to check his technique for inhaling the drug. Patients should be warned about the possibility of a different taste compared to that when using the previous inhaler.

An increased need for bronchodilators, especially inhaled β ₂ -adrenergic agonists, to control asthma symptoms indicates an exacerbation of the disease. In these cases, the treatment plan should be reviewed and the question of prescribing higher doses of inhaled corticosteroids or a course of oral corticosteroids should be considered.

Sudden and progressive worsening of asthma is a life-threatening condition requiring initiation or increased frequency of corticosteroid use. Patients at risk are advised to monitor the maximum expiratory flow rate daily.

Bronchodilator drugs should not be the only or primary treatment for patients with severe or unstable asthma. The condition of such patients should be regularly monitored, including pulmonary tests, since severe asthma is a life-threatening disease, and for the treatment of such patients, the issue of prescribing the maximum recommended doses of inhaled and / or oral corticosteroids should be decided.

If the effect of the usual dose of the drug becomes less effective or the duration of its action decreases (less than 3 hours), the patient should consult a doctor. Increasing the dose or frequency of use of the drug is carried out only by a doctor.

A severe exacerbation of asthma should be treated as usual.

Sympathomimetics, including salbutamol, affect the cardiovascular system. According to post-registration use and published data, there is evidence of rare cases of myocardial ischemia associated with the use of salbutamol. Patients with heart disease (for example, coronary artery disease, arrhythmias, or severe heart failure) who are treated with salbutamol should seek medical attention if they develop chest pain or other symptoms that indicate an exacerbation of heart disease. Attention should be paid to the assessment of symptoms such as shortness of breath and chest pain, which can be due to both heart disease and respiratory system disease.

Salbutamol should be used with caution in patients with thyrotoxicosis.

Treatment with β ₂ -adrenergic agonists can result in severe hypokalemia, mainly observed with the use of parenteral forms or a nebulizer. Particular attention is paid to patients with acute severe asthma, since hypokalemia can be potentiated by the concomitant use of xanthine derivatives, steroids, diuretics and hypoxia. In this situation, it is recommended to control the level of potassium in the blood plasma.

Salbutamol is used with caution in patients receiving high doses of other sympathomimetics. Like other β-adrenergic agonists, salbutamol can lead to reverse metabolic changes, such as an increase in blood glucose levels. Compensation for such changes in diabetic patients is not always possible, so there are separate reports of the development of ketoacidosis in such patients. Concomitant use of corticosteroids may exacerbate this condition.

As with other inhalation drugs, paradoxical bronchospasm may occur with an immediate increase in dyspnoea after the use of the drug. In this case, it is necessary to immediately prescribe alternative forms of the drug or other fast-acting inhaled bronchodilators. Salbutamol should be discontinued immediately, the patient assessed and, if necessary, another rapid-acting bronchodilator be prescribed on an ongoing basis.

Use during pregnancy and lactation . According to animal studies, salbutamol has reproductive toxicity. The safety of use in pregnant women has not been established. Controlled clinical studies on the use of salbutamol in pregnant women have not been conducted. There have been sporadic reports of various congenital malformations in utero, including cleft palate, limb defects, and cardiac abnormalities. Some women took many other medicines during pregnancy. Salbutamol should not be taken during pregnancy, it is prescribed only in case of emergency.

Salbutamol is likely to pass into breast milk and should therefore be administered with caution to women who are breastfeeding. Whether salbutamol in mother’s breast milk has a harmful effect on the infant is unknown, therefore its use during lactation should be limited to cases where the benefit to the woman will outweigh the possible risk to the child.

Children . The drug is intended for the treatment of children aged 4 years.

The ability to influence the reaction rate when driving vehicles or operating other mechanisms . There are no data on the effect, in the event of adverse reactions from the nervous system (tremor), driving or working with mechanisms must be limited.

Salbutamol should not be used with non-selective β-blockers (eg propranolol).

Simultaneous use of salbutamol with MAO inhibitors is not contraindicated.

The most common signs and symptoms of salbutamol overdose are transient changes pharmacologically induced by β ₂ -adrenergic receptor agonists, such as tachycardia, tremor, hyperactivity, and metabolic disturbances, including hypokalemia (see SPECIAL INSTRUCTIONS and SIDE EFFECTS).

An overdose of salbutamol may result in hypokalemia, therefore it is necessary to control the level of potassium in the blood plasma. When using high therapeutic doses or an overdose of β 9 agonists0031 2 short-acting α-adrenergic receptors, cases of lactic acidosis have been reported, therefore plasma lactate levels and, accordingly, metabolic acidosis should be monitored, especially in case of persistent or increasing rapid breathing, despite improvement in symptoms of bronchospasm, such as stridor breathing.

below 30°C. Do not freeze. Avoid exposure to direct sunlight. Do not disassemble, puncture or incinerate the cylinder even after full use.

You can report an adverse event to GlaxoSmithKline Pharmaceuticals Ukraine LLC by phone: (044) 585-51-85 or e-mail: [email protected] You can complain about the quality of the drug by phone: (044) 585 -51-85, +38 (050) 381-43-49 or e-mail: [email protected]

Pavel Tychyna, 1B.

Tel. : (044) 585-51-85, fax: (044) 585-51-92.

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Information for the professional activities of medical and pharmaceutical workers.

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instructions for use, dosages, composition, analogues, side effects / Pillintrip

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Top 20 drugs with the same ingredients:

Asthalin AXLevolin INHALERLevolin RESPULESLevosalbutamol/Salbutamol

Name of the medicine

Description The name of the medicine Levosalbutamol/Salbutamol is an automatic translation from the original language.
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Levosalbutamol / salbutamol

Therapeutic indications

Description Therapeutic indications Levosalbutamol/Salbutamol is an automatic translation from the original language.
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An indication is a term used to list a condition or symptom or illness for which a drug is prescribed or used by a patient. For example, acetaminophen or paracetamol is used by a patient for a fever, or a doctor prescribes it for a headache or body aches. Currently, fever, headache and body aches are signs of paracetamol. The patient must be aware of the indications of the drugs used for general conditions because they can be taken over the counter in the sense of a pharmacy without a doctor’s prescription.

Prevention and relief of bronchospasm in all forms of bronchial asthma. Reversible airway obstruction in chronic bronchitis and emphysema, bronchial obstruction in children.

Risk of preterm labor due to uterine contractions; birth before 37-38 weeks of pregnancy; isthmic-cervical insufficiency, a decrease in the heart rate of the fetus, depending on uterine contractions during the opening of the cervix and expulsion. As a preventive measure during surgery on the pregnant uterus (imposition of a round suture with the absence of an internal wasp of the uterus).

An indication is a term used to list a condition or symptom or disease for which a drug is prescribed or used by a patient. For example, acetaminophen or paracetamol is used by a patient for a fever, or a doctor prescribes it for a headache or body aches. Currently, fever, headache and body aches are signs of paracetamol. The patient must be aware of the indications of the drugs used for general conditions because they can be taken over the counter in the sense of a pharmacy without a doctor’s prescription.

Salbutamol® (desogestrel and ethinyl estradiol) Tablets are indicated for the prevention of pregnancy in women who choose to use this product as a method of contraception.

Oral contraceptives are very effective. Table 1 lists typical unwanted pregnancy rates for users of combined oral contraceptives and other contraceptive methods. The effectiveness of these methods of contraception, other than sterilization, IUDs, and implants, depends on the reliability with which they are used. Proper and consistent use of these methods can lead to a reduction in failure rates.

Albuterol is used to treat or prevent bronchospasm in patients with asthma, bronchitis, emphysema, and other lung conditions. This medicine is also used to prevent exercise-induced wheezing (exercise-induced ancrochospasm).

Albuterol belongs to a family of drugs known as adrenergic bronchodilators. Adrenergic bronchodilators are medications that are inhaled through the mouth to open the bronchi (air passages) in the lungs. They relieve cough, shortness of breath, wheezing and shortness of breath by increasing the flow of air through the bronchial tubes.

This medicine is only available with a prescription from your doctor.

Once a drug has been approved for marketing for a particular use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, albuterol is used in some patients with the following condition:

• Hyperkalemia (too much potassium in the blood).

Dosage and administration

Description Dosage and Administration Levosalbutamol/Salbutamol is an automatic translation from the original language.
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Levosalbutamol for oral use as a bronchial enlargement agent in adults and children over 12 years old – 2.4 mg 3-4 times a day; if necessary, the dose may be increased to 8 mg 4 times a day. Children aged 6-12 years – 2 mg 3-4 times a day; children 2-6 years old – 1-2 mg 3 times a day.

Levosalbutamol for inhalation The dose depends on the dosage form used, the frequency of use depends on the indication and the clinical situation.

As a tocolytic used as an intravenous infusion at a dose of 1-2 mg.

The usual starting dose for patients aged 2 to 12 years is 1.25 mg or 0.63 mg of salbutamol (albuterol sulphate inhalant) given 3 or 4 times daily, as needed, by spray. More frequent administration is not recommended.

To administer 1.25 mg or 0.63 mg albuterol, use the entire contents of one single dose vial (3 ml of 1.25 mg or 0.63 mg inhalation solution) by spray. Adjust the flow rate of the nebulizer to deliver salbutamol (albuterol sulfate inhalant solution) within 5 to 15 minutes.

The use of salbutamol (albuterol sulfate inhalant) may be continued as medically indicated to control recurrent episodes of bronchospasm. During this time, most patients benefit optimally from regular use of the inhalation solution.

Patients aged 6 to 12 years with more severe asthma (baseline FEV less than 60% predicted), weight > 40 kg, or patients aged 11 to 12 years may achieve a better initial response with a dose of 1. 25 mg.

Salbutamol (albuterol sulfate inhalant) has not been studied in acute bronchoconstriction. The 2.5 mg dose of albuterol provided by the higher concentration product (2.5 mg albuterol per 3 ml) may be more appropriate for the treatment of acute exacerbations, especially in children 6 years of age and older.

If a previously effective dosing regimen does not provide the usual relief, you should immediately consult a doctor, as this is often a sign of a serious exacerbation of asthma, which will require re-evaluation of therapy.

Drug compatibility (physical and chemical), clinical efficacy and safety of salbutamol solution (albuterol sulfate inhalation solution) when mixed with other drugs in a nebulizer have not been established.

The safety and efficacy of salbutamol (albuterol sulfate inhalation solution) have been established in clinical trials when administered using the Pari LC Plus™ Nebulizer and Pari PRONEB™ Compressor. The safety and efficacy of salbutamol (albuterol sulfate inhalant) when administered with other nebulizer systems have not been established.

Salbutamol (albuterol sulfate inhalant) should be administered through a jet nebulizer connected to an air compressor with sufficient air flow, fitted with a mouthpiece or a suitable face mask.

How Supplied

Salbutamol (albuterol sulfate) Inhalation Solution is supplied as a 3 ml, clear, colorless, sterile, preservative free, aqueous solution in two different strengths, 0.63 mg and 1.25 mg, of albuterol (equivalent to 0 .75 mg albuterol sulfate or 1.5 mg albuterol sulfate per 3 ml) in single dose low-density polyethylene (LDPE) vials. Each single dose LDPE vial is protected in foil and each foil pouch contains 5 single dose LDPE vials. Each strength of salbutamol (albuterol sulfate inhalant) (albuterol sulfate) inhalation solution comes in a carton containing several foil pouches.

Salbutamol® (Albuterol Sulfate) Inhalation Solution 0.63 mg (potency expressed as albuterol) contains 0.75 mg albuterol sulfate per 3 mL in single dose vials and is available in the following packaging configuration.

NDC 49502-692-03 5 foil pouches, each containing 5 vials, for a total of 25 vials per box in the form albuterol) contains 1.50 mg albuterol sulfate per 3 ml in single dose vials and is available in the following packaging configuration.

NDC 49502-693-03 5 foil pouches, each containing 5 vials, for a total of 25 vials per box

Storage

Store between 2°C and 25°C (36°F – 77° F). Keep away from light and excessive heat.

Store single dose vials in protective foil pouch at all times. Once removed from foil pouch, use vial(s) within one week. Discard the vial if the solution is not colorless.

Keep out of reach of children.

DEY®, Napa, CA 94558. Jan 07

Contraindications

Description Contraindications Levosalbutamol/Salbutamol is an automatic translation from the original language.
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Threatened miscarriage in the first and second trimesters of pregnancy, premature termination of the placenta, bleeding or toxemia in the third trimester of pregnancy, infancy up to 2 years; hypersensitivity to salbutamol.

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What is the most important information I should know about salbutamol?

Oral contraceptives should not be used in women who currently have the following conditions:

• Thrombophlebitis or thromboembolic disorders
• Past history of deep vein thrombophlebitis or thromboembolic disorders
• Cerebral vascular or coronary heart disease (current or historical)
• Boulder heart disease with thrombogenic complications
• Severe hypertension
• Diabetes with vascular involvement m
• Headaches with focal neurological symptoms
• Major surgery with prolonged immobilization
• Known or suspected breast cancer (or personal history of breast cancer)
• Endometrial carcinoma or other known or suspected estrogen-dependent neoplasia
• Undiagnosed abnormal genital bleeding
• Cholestatic jaundice of pregnancy or jaundice with previous hormonal contraceptive
• Liver tumors (benign or malignant) or active liver disease
• Known or suspected pregnancy
• Severe smoking (≥15 cigarettes per day) and older than 35 years
• Increased sensitivity to any of the components of the tablets of salbutamol® (deogstrel and ethinyl estradiol)

Special warnings and precautions of

Special warnings and precautions of the Levosalbutamol/Salbutamol is an automatic translation with language original.
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There are both specific and general uses of a drug or drug. A medicine can be used to prevent a disease, treat a disease for a period, or treat a disease. It can also be used to treat a specific symptom of a disease. The use of the drug depends on the form that the patient takes. It may be more useful in the form of an injection or sometimes in the form of a tablet. The drug may be used for a single alarm symptom or life-threatening condition. While some medications can be stopped after a few days, some medications must be continued for a long period of time to benefit from them.

For the treatment and prevention of bronchospasm (airway restriction causing difficulty breathing) in reversible obstructive airway disease such as asthma or some cases of chronic bronchitis.

There are both specific and general uses of a drug or drug. A medicine can be used to prevent a disease, treat a disease for a period, or treat a disease. It can also be used to treat a specific symptom of a disease. The use of the drug depends on the form that the patient takes. It may be more useful in the form of an injection or sometimes in the form of a tablet. The drug may be used for a single alarm symptom or life-threatening condition. While some medications can be stopped after a few days, some medications must be continued for a long period of time to benefit from them.

Salbutamol is used to prevent reversible airway obstruction that occurs during asthma, respiratory tract infections (bronchitis), lung disorders in which airflow to the lungs is blocked (emphysema), and other lung diseases.

Interaction with other drugs

Description Interaction with other drugs Levosalbutamol/Salbutamol is an automatic translation from the original language.
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Diuretics, corticosteroids and xanthines can exacerbate hypokalemia. CV effects enhanced by MAOI, TCA, sympathomimetics. Increases absorption of sulfamethoxazole when used together. May markedly increase heart rate and BP when used with atomoxetine. Reduces serum digoxin levels. Salbutamol-induced hypokalemia increases the risk of digitalis toxicity. BP should be carefully monitored if linezolid is used concomitantly with salbutamol.

See also:
What other medicines will affect salbutamol?

Concomitant use of salbutamol (albuterol sulfate syrup) and other oral sympathomimetics is not recommended as this combined use may lead to harmful cardiovascular effects. This recommendation does not preclude the prudent use of an adrenergic stimulant-type aerosolized bronchodilator in patients receiving salbutamol (albuterol sulfate syrup). Such concomitant use, however, must be individualized and not provided on a regular basis. If regular co-administration is required, alternative therapy should be considered.

Beta-blockers

Beta-adrenergic receptor blocking agents not only block the pulmonary effect of beta-agonists such as salbutamol (albuterol sulfate syrup), but can cause severe bronchospasm in patients with asthma. Therefore, patients with asthma should not usually be treated with beta-blockers. However, under certain circumstances, for example, as a prophylaxis after myocardial infarction, there may not be acceptable alternatives to the use of beta-adrenergic blocking agents in patients with asthma. In this case, cardioselective beta-blockers may be considered, although they should be used with caution.

Diuretics

ECG changes and/or hypokalemia that may result from the administration of non-potassium-sparing diuretics (such as loop or thiazide diuretics) may be drastically aggravated by beta-agonists, especially when the recommended beta-agonist dose is exceeded. Although the clinical significance of these effects is unknown, caution is advised when beta-agonists are coadministered with non-potassium-sparing diuretics.

Digoxin

A mean decrease in serum digoxin levels was demonstrated after single intravenous and oral administration of albuterol, respectively, to normal volunteers who received digoxin for 10 days. The clinical significance of these findings for patients with obstructive airway disease who receive albuterol and digoxin on a chronic basis is unclear. However, it would be prudent to carefully evaluate serum digoxin levels in patients currently receiving digoxin and albuterol.

Monoamine oxidase inhibitors or tricyclic antidepressants

Albuterol should be administered with extreme caution in patients treated with monoamine oxidase inhibitors or tricyclic antidepressants, or within 2 weeks after discontinuation of such agents, since the effect of albuterol on the vascular system may increase.

Side effects

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Cardiovascular system: temporary dilation of peripheral blood vessels, mild tachycardia.

Central nervous system: headache, dizziness, nausea, vomiting.

Metabolic: hypokalemia.

Allergic reactions: in some cases – angioedema, allergic reactions in the form of skin rash, urticaria, hypotension, collapse.

Other: hand trembling, internal trembling, tension, rarely paradoxical bronchospasm, muscle spasms.

See also:
What are the possible side effects of salbutamol?

Clinical Trial Experience: Adverse events reported in >1% of patients treated with salbutamol (albuterol sulfate inhalant solution) and more frequently than in patients treated with placebo in a four-week double-blind study are listed in the following table.

Table 1: Adverse events with an incidence of > 1% in patients receiving salbutamol (albuterol sulfate inhalant solution) and more than placebo (as a percentage of the treatment group)

	1. 25 mg salbutamol (N=115)	0.63 mg salbutamol (N=117)	Placebo (N = 117)
Exacerbation asthma	13	11.1	8.5
Otitis Media	4.3	0.9	0
Allergic reaction	0.9	3.4	1 .7
Gastroenteritis	0.9	3.4	0.9
Cold symptoms	0 9049 4	3.4	1.7
Flu syndrome	2.6	2, Dermal / Adnexal infection	1.7	0	0
Urticaria	1.7	0.9	0
Migraine	0.9	1.7	0
Chest pain	0.9	1 .7	0
Bronchitis	0.9	1.7	0.9
Nausea 90 494	1. 7	0.9	0.9

There was one case of ST segment depression in the 1.25 mg salbutamol (albuterol sulfate inhalation solution) treatment group.

There were no clinically significant laboratory abnormalities associated with the administration of salbutamol (albuterol sulfate inhalation solution) in this study.

Post-marketing experience

Metabolic acidosis has been reported following use of albuterol sulfate inhalation solution. Because this reaction is reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate its frequency or establish a causal relationship to drug exposure..

Composition

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Each 200 µg/dose of powder for inhalation solution contains salbutamol sulfate equivalent to 200 µg salbutamol per dose. The dose that the patient receives through the mouthpiece of the device is salbutamol 180 mcg.

Contains lactose monohydrate (milk protein) as an excipient.

Salbutamol Multi-dose powder inhaler contains 200 doses of finely divided salbutamol sulfate mixed with a small amount of lactose. The amount of drug received by the patient (180 µg/dose) corresponds to the amount of aerosol when salbutamol is inhaled. The inhalation dose is released from the container by pressing the device between thumb and forefinger.