What are AST and ALT levels. How do these enzymes relate to liver health. Why are AST and ALT tests important for diagnosing liver conditions. What do abnormal AST and ALT levels indicate. How are these tests performed and interpreted.

The Importance of AST and ALT in Liver Function Assessment

Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) are enzymes primarily found in the liver. These enzymes play a crucial role in amino acid metabolism and are often used as biomarkers to assess liver health. When liver cells are damaged or die, AST and ALT are released into the bloodstream, causing their levels to rise. This makes AST and ALT tests valuable tools for diagnosing and monitoring liver diseases.

What exactly are AST and ALT?

AST, also known as serum glutamic oxaloacetic transaminase (SGOT), is an enzyme found in various tissues, including the liver, heart, muscles, and kidneys. ALT, formerly called serum glutamic pyruvic transaminase (SGPT), is more specific to the liver. Both enzymes catalyze the transfer of amino groups between amino acids, playing a vital role in metabolism.

Why are AST and ALT levels important?

Elevated AST and ALT levels in the blood can indicate liver cell damage or death. This makes these enzymes valuable markers for:

• Detecting liver diseases
• Monitoring the progression of liver conditions
• Evaluating the effectiveness of treatments
• Assessing overall liver function

Understanding AST and ALT Test Results

Interpreting AST and ALT test results requires considering various factors, including age, sex, and overall health. Normal ranges may vary slightly between laboratories, but generally:

What are normal AST and ALT levels?

• AST: 5 to 40 units per liter (U/L)
• ALT: 7 to 56 U/L

It’s important to note that these ranges can differ based on individual factors and the specific laboratory conducting the test.

What do elevated AST and ALT levels indicate?

Increased AST and ALT levels often suggest liver damage or disease. Some conditions associated with elevated levels include:

• Hepatitis (viral, alcoholic, or autoimmune)
• Cirrhosis
• Nonalcoholic fatty liver disease (NAFLD)
• Drug-induced liver injury
• Liver cancer

However, elevated levels don’t always indicate liver problems. AST can also increase due to heart or muscle damage, while ALT is more liver-specific.

The AST/ALT Ratio: A Valuable Diagnostic Tool

The ratio of AST to ALT can provide additional insights into liver health and help differentiate between various liver conditions.

How is the AST/ALT ratio calculated and interpreted?

The AST/ALT ratio is simply the AST level divided by the ALT level. A ratio greater than 1 (where AST is higher than ALT) can indicate more severe liver damage, such as cirrhosis. Conversely, a ratio less than 1 is often seen in less severe conditions like viral hepatitis or fatty liver disease.

What specific conditions can the AST/ALT ratio help identify?

• Alcoholic liver disease: AST/ALT ratio often > 2
• Nonalcoholic fatty liver disease: AST/ALT ratio usually < 1
• Viral hepatitis: AST/ALT ratio typically < 1 in acute phases
• Cirrhosis: AST/ALT ratio often > 1 as the disease progresses

Factors Affecting AST and ALT Levels

Several factors can influence AST and ALT levels, potentially leading to false positives or negatives. Understanding these factors is crucial for accurate interpretation of test results.

Which medications can affect AST and ALT levels?

Certain medications can cause elevated AST and ALT levels, including:

• Acetaminophen (in high doses)
• Some antibiotics (e.g., isoniazid, tetracycline)
• Statins (cholesterol-lowering drugs)
• Nonsteroidal anti-inflammatory drugs (NSAIDs)
• Some antiepileptic medications

Can lifestyle factors impact AST and ALT levels?

Yes, several lifestyle factors can affect AST and ALT levels:

• Alcohol consumption
• Obesity
• Intense exercise (particularly for AST)
• Diet (e.g., high protein intake)

The Process of AST and ALT Testing

AST and ALT tests are typically part of a comprehensive metabolic panel or liver function tests. Understanding the testing process can help patients prepare and alleviate any concerns.

How are AST and ALT tests performed?

The test involves a simple blood draw, usually from a vein in the arm. A healthcare professional will:

1. Clean the area with an antiseptic
2. Insert a small needle to draw blood
3. Collect the blood in a vial or tube
4. Apply pressure to stop bleeding and bandage the site

The entire process typically takes less than five minutes.

Is fasting required before AST and ALT tests?

Fasting is not always necessary for AST and ALT tests. However, since these tests are often part of a larger panel of liver function tests or a comprehensive metabolic panel, fasting for 8-12 hours may be required. Always follow your healthcare provider’s instructions regarding preparation for the test.

Beyond AST and ALT: Other Important Liver Function Tests

While AST and ALT are crucial markers of liver health, they are often used in conjunction with other tests to provide a comprehensive picture of liver function.

Which other tests complement AST and ALT in assessing liver health?

Other important liver function tests include:

• Alkaline phosphatase (ALP)
• Gamma-glutamyl transferase (GGT)
• Bilirubin
• Albumin
• Prothrombin time (PT)

These tests, along with AST and ALT, provide a more complete assessment of liver function and can help pinpoint specific liver conditions.

How do these additional tests contribute to liver health assessment?

Each test offers unique insights:

• ALP and GGT: Indicate bile duct problems
• Bilirubin: Helps diagnose conditions like jaundice and hemolytic anemia
• Albumin: Reflects the liver’s ability to synthesize proteins
• PT: Measures blood clotting function, which can be impaired in severe liver disease

Monitoring AST and ALT Levels: When and Why

Regular monitoring of AST and ALT levels is crucial for individuals with known liver conditions or those at risk of developing liver disease. Understanding when and why these tests are performed can help patients take a proactive approach to their liver health.

How often should AST and ALT levels be checked?

The frequency of AST and ALT testing depends on individual circumstances:

• Healthy individuals: Often part of routine annual check-ups
• Patients with liver disease: May require testing every 3-6 months or more frequently
• Those on hepatotoxic medications: Regular monitoring as advised by healthcare provider
• Individuals with risk factors: May need more frequent testing

Why is ongoing monitoring of AST and ALT levels important?

Regular monitoring serves several purposes:

• Early detection of liver problems
• Tracking progression of known liver conditions
• Assessing effectiveness of treatments
• Identifying potential medication-related liver damage
• Motivating lifestyle changes to improve liver health

By consistently monitoring AST and ALT levels, healthcare providers can detect changes early and intervene promptly, potentially preventing more serious liver complications.

Lifestyle Modifications to Improve AST and ALT Levels

For individuals with elevated AST and ALT levels, certain lifestyle changes can help improve liver health and potentially normalize enzyme levels. These modifications are often recommended alongside medical treatments for liver conditions.

Which dietary changes can positively impact AST and ALT levels?

Adopting a liver-friendly diet can help reduce AST and ALT levels:

• Increase intake of fruits, vegetables, and whole grains
• Limit saturated fats and processed foods
• Reduce sugar consumption
• Maintain adequate hydration
• Consider coffee consumption (studies suggest it may have protective effects on the liver)

How can exercise influence AST and ALT levels?

Regular physical activity can positively impact liver health:

• Helps reduce liver fat accumulation
• Improves insulin sensitivity
• Aids in weight management
• Enhances overall metabolic health

However, it’s important to note that intense exercise can temporarily elevate AST levels, so timing of blood tests should be considered.

Other lifestyle modifications that can improve AST and ALT levels include:

• Limiting or avoiding alcohol consumption
• Maintaining a healthy weight
• Managing stress through relaxation techniques
• Avoiding exposure to toxins and chemicals

By implementing these lifestyle changes, individuals can support their liver health and potentially improve their AST and ALT levels. However, it’s crucial to work closely with a healthcare provider to develop a comprehensive plan tailored to individual needs and medical conditions.

The Future of Liver Function Testing: Beyond AST and ALT

While AST and ALT remain cornerstone tests in liver function assessment, ongoing research is exploring new biomarkers and technologies to enhance liver disease diagnosis and monitoring. These advancements aim to provide more accurate, comprehensive, and non-invasive methods of assessing liver health.

What are some emerging biomarkers for liver function assessment?

Researchers are investigating several promising biomarkers:

• Cytokeratin-18 (CK-18): A marker of hepatocyte apoptosis
• microRNAs: Small RNA molecules that can indicate specific liver pathologies
• Enhanced Liver Fibrosis (ELF) test: Combines three serum biomarkers to assess liver fibrosis
• M30 and M65: Markers of cell death that may help differentiate between types of liver injury

How might technology improve liver function testing in the future?

Technological advancements are shaping the future of liver diagnostics:

• Transient elastography (FibroScan): Uses ultrasound to measure liver stiffness
• Magnetic Resonance Elastography (MRE): Combines MRI with sound waves to create a visual map of liver stiffness
• Artificial Intelligence: Machine learning algorithms to interpret complex liver function data
• Metabolomics: Analyzing metabolic profiles to identify liver disease signatures

These emerging technologies and biomarkers hold the potential to provide earlier detection, more accurate staging, and better monitoring of liver diseases. As research progresses, they may complement or even replace traditional AST and ALT tests in certain situations, offering a more nuanced understanding of liver health.

However, it’s important to note that while these advancements are promising, AST and ALT tests remain valuable tools in liver function assessment. The integration of new technologies and biomarkers with established tests like AST and ALT will likely provide the most comprehensive approach to liver health evaluation in the future.

As our understanding of liver function and disease mechanisms continues to evolve, so too will our diagnostic and monitoring capabilities. This ongoing progress underscores the importance of staying informed about liver health and working closely with healthcare providers to leverage the most appropriate and effective tools for individual liver care.

AST Test: MedlinePlus Medical Test

What is an AST Test?

AST (aspartate aminotransferase) is an enzyme that is found mostly in the liver, but it’s also in muscles and other organs in your body. When cells that contain AST are damaged, they release the AST into your blood. An AST blood test measures the amount of AST in your blood. The test is commonly used to help diagnose liver damage or disease.

Other names: SGOT test, serum glutamic oxaloacetic transaminase test; aspartate transaminase test

What is it used for?

An AST blood test is often part of a routine blood screening to check the health of your liver. The test may help diagnose or monitor liver problems. It may also help diagnose other health conditions.

Why do I need an AST blood test?

You may get an AST blood test as part of your routine checkup or if you have symptoms of liver damage. These may include:

• Nausea and vomiting
• Lack of appetite
• Fatigue
• Weakness
• Jaundice, a condition that causes your skin and eyes to turn yellow
• Swelling and/or pain in your abdomen (belly)
• Swelling in your ankles and legs
• Dark-colored urine (pee) and/or light-colored stool (poop)
• Frequent itching

Even if you don’t have symptoms, your health care provider may order an AST blood test if you’re more likely to develop liver disease because of:

• A family history of liver disease
• Alcohol use disorder
• Obesity
• Diabetes
• Taking certain medicines that can cause liver damage
• Hepatitis or exposure to hepatitis

What happens during an AST blood test?

A health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.

Will I need to do anything to prepare for the test?

You don’t need any special preparations for an AST blood test. But an AST test is usually ordered with other blood tests. You usually need to fast (not eat or drink) for up to 12 hours before these tests. Your provider will let you know if there are any special instructions to follow.

Are there any risks to the test?

There is very little risk to having a blood test. You may have slight pain or bruising at the spot where the needle was put in, but most symptoms go away quickly.

What do the results mean?

High levels of AST in the blood may be a sign of hepatitis, cirrhosis, mononucleosis, or other liver diseases. High AST levels may also be a sign of heart problems or pancreatitis.

If your results are not in the normal range, it doesn’t always mean that you have a medical condition that needs treatment. Many things can affect your results, such as certain medicines and your age, sex, and diet. To learn what your results mean, talk with your provider.

Learn more about laboratory tests, reference ranges, and understanding results.

Is there anything else I need to know about an AST blood test?

Your health care provider may order an ALT blood test with your AST blood test. ALT stands for alanine transaminase, which is another type of liver enzyme. If you have high levels of AST and/or ALT, it may mean that you have some type of liver damage.

You may also have an AST test as part of a group of liver function tests that measure ALT, and other enzymes, proteins, and substances in the liver.

References

1. American Liver Foundation. [Internet]. New York: American Liver Foundation; c2017. Diagnosing Liver Disease – Liver Biopsy and Liver Function Tests; [updated 2020 Feb 17; cited 2022 Feb 14]; [about 3 screens]. Available from: https://liverfoundation. org/for-patients/about-the-liver/diagnosing-liver-disease/
2. Hinkle J, Cheever K. Brunner & Suddarth’s Handbook of Laboratory and Diagnostic Tests. 2nd Ed, Kindle. Philadelphia: Wolters Kluwer Health, Lippincott Williams & Wilkins; c2014. Aspartate Aminotransferase; p. 68–69.
3. National Heart, Lung, and Blood Institute [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; Blood Tests; [cited 2022 Feb 14]; [about 15 screens]. Available from: https://www.nhlbi.nih.gov/health-topics/blood-tests
4. Testing.com [Internet]. Seattle (WA).: OneCare Media; c2022. Aspartate Aminotransferase: The Test; [modified 2021 Nov 9; cited 2022 Feb 14; [about 14 screens]. Available from: https://www.testing.com/test/aspartate-aminotransferase-ast/
5. University of Rochester Medical Center [Internet]. Rochester (NY): University of Rochester Medical Center; c2017. Health Encyclopedia: Aspartate Transaminase; [cited 2017 Mar 13]; [about 2 screens]. Available from: https://www. urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=aspartate_transaminase

High and low levels, and what do results mean

An AST blood test measures levels of aspartate aminotransferase (AST) and helps determine liver function. Too much of this enzyme can indicate a problem, such as liver damage.

Aspartate aminotransferase (AST) is an enzyme mostly found in the liver. AST is also present in other parts of the body, including the:

• kidneys
• heart
• muscles

Another name for the AST enzyme is serum glutamic-oxaloacetic transaminase (SGOT).

Most people have low levels of the AST enzyme. Damage to liver cells can cause the release of extra AST into the blood though, leading to higher levels of the enzyme.

After taking a blood test, doctors will classify AST ranges as normal, high, or low. Laboratories may use different testing methods for analyzing samples, so normal ranges can vary between each laboratory.

There is not an exact range for AST levels, as levels can vary among people and still be normal. AST levels can vary depending on factors such as:

• age
• sex
• weight
• race

The measurements for AST levels are typically in units per liter (U/L) or international units per liter (IU/L). On a test result, the laboratory will usually list their specific reference range.

People will need to look at this reference range and discuss with their doctor what their test results mean for them. To understand the results of an AST blood test, a doctor will also look at other enzymes that can indicate a liver problem.

The following table indicates general AST blood test ranges. However, reference ranges can vary slightly among different laboratories.

Results from an AST blood test can help indicate liver health.

If AST levels are high, it may also be a sign of:

• chronic hepatitis
• damage from alcohol
• cholestasis, a decrease in bile flow
• heart, kidney, bone, or muscle damage
• liver cancers
• liver scarring, known as liver cirrhosis

Very high AST levels are usually a sign of progressing liver damage, often due to acute hepatitis.

Low AST levels may indicate:

• vitamin B6 deficiency
• kidney disease
• liver disease
• cirrhosis
• cancer
• autoimmune conditions
• genetic conditions

A doctor may also test levels of alanine aminotransferase (ALT), another liver enzyme. ALT levels occur in higher concentrations in the liver.

If ALT levels are normal but AST levels are high, it could indicate a health problem outside of the liver, or it may be a sign of alcohol-induced liver damage.

Having high levels of AST and no other signs of a problem is not necessarily a cause for concern. People with normal liver function can have high AST levels, which may be due to:

• age
• sex
• race
• certain medications

A person should always discuss any medications or health products they take with a doctor.

Doctors primarily use the AST blood test to check for and assess liver problems, usually alongside other liver tests. The AST protein mainly occurs in the liver and heart. With liver damage, AST can leak from the liver into the bloodstream. When this happens, AST levels in the blood will be higher than normal.

AST also occurs in the brain, heart, kidneys, and muscles. If there is damage in any of these areas, AST levels may also increase.

To rule out issues affecting areas outside the liver, doctors may order a check of the second liver enzyme, ALT, at the same time. If both levels are high, it may indicate a problem with a person’s liver. If only AST levels are high, this may indicate a problem with another organ or system.

People may have an AST test for screening, diagnosis, or monitoring purposes. A doctor may recommend this test if a person:

• has risk factors for liver disease, such as family history, obesity, or diabetes
• has symptoms of a liver problem, such as jaundice, fatigue, or unexplained weight loss
• is undergoing treatment for a liver condition, as an AST blood test can help show how well treatment is working

Alanine aminotransferase (ALT) is an enzyme that mostly occurs in the liver. If there is damage to liver cells, ALT levels in the bloodstream can increase. An ALT test can help indicate liver health, along with other liver enzyme tests.

Healthcare professionals may use both ALT and AST tests to check for the presence of liver enzymes in the blood, as this can give them a clearer idea of overall liver function and health.

Learn more about the ALT test here.

The AST blood test is straightforward and similar to any other blood test. A healthcare professional may take the following steps:

• sit the person down and tie a stretchy band around the upper arm to increase blood flow to that area
• clean the site of the blood draw with an antiseptic wipe
• insert a needle into a vein in the arm to take a blood sample, which may cause people to feel a mild prick or pain
• remove the needle once they have drawn enough blood
• send the blood sample to a laboratory for testing

An AST blood test will usually only take a few minutes in total.

In some cases, people may be able to take an AST test at home. Using an at-home test kit, people will take a blood sample from their fingertip and send the sample to a laboratory. People may receive AST blood test results through the mail, an app, or an online system.

Learn how long it might take to receive blood test results here.

Preparation

People may need to fast for several hours if they are having a combination of liver enzyme tests.

If people are only having an AST blood test, they may not need to fast or prepare in any way.

People will need to let their doctor know if they are taking any medications or supplements, as some may interfere with liver enzyme levels.

As a healthcare professional will be taking blood from the arm, it may be helpful to wear short sleeves during the test.

As with any blood test, an AST blood test has very few risks. It is rare to experience any severe side effects, but people may have some mild bruising or discomfort in the area at the site of the blood draw.

A healthcare professional will place a Band-Aid or bandage on the arm to stop any bleeding.

People may want to have something to eat after the test, particularly if they were fasting beforehand. It is safe for people to drive and continue their usual activities after an AST blood test, unless they experience any unusual symptoms.

A doctor may order tests along with an AST blood test or follow-up tests. This is to help ensure proper diagnosis and determine the best course of treatment. These tests may include:

• ALT test: A doctor may order an ALT test alongside an AST test.
• Platelet count: Low platelet levels may indicate HELLP syndrome during pregnancy.
• Coagulation panel: This measures the functioning of clotting-related proteins that the liver produces.
• Complete metabolic panel: This assesses how well the kidneys and liver are working and shows levels of electrolytes.
• Bilirubin test: A bilirubin test checks levels of a byproduct created when the liver breaks down red blood cells.
• Glucose test: High or low blood glucose levels may indicate a liver problem.
• Viral testing: This can help doctors check for hepatitis.
• Imaging: A doctor may order images of the liver via ultrasound.

The extent of follow-up testing will depend on a person’s results. A doctor may also take additional blood tests, imaging tests, or a biopsy to identify or rule out any potential conditions relating to abnormal AST levels.

Learn about different types of blood tests here.

An AST blood test, or SGOT test, checks how much AST, a liver enzyme, is present in the blood. High levels of AST in the bloodstream could be a sign of liver damage, or cell damage in another organ such as the heart or kidneys.

Doctors may also take additional tests to check other liver enzymes, such as ALT, to get more information on the health of the liver.

Liver test (ALT, AST, total bilirubin, GGT)

Code: 142

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Liver test (ALT, AST, total bilirubin, GGT)

One of the comprehensive studies of liver function is a screening blood test for ALT, AST, GGT and total bilirubin.

ALT and AST enzymes are specific markers of hepatic pathologies: with viral hepatitis and toxic liver damage, an increase in these indicators is noted. If a neoplasm has developed in the liver or the patient has cirrhosis, aspartate aminotransferase levels will be higher compared to alanine aminotransferase.

GGT is the most sensitive enzyme, the concentration of which necessarily changes in liver diseases. The diagnostic value of this indicator is high in detecting blockage of the bile ducts: its level rises up to 30 times. High levels of gamma-glutamyl transpeptidase may indicate liver metastases or alcoholic cirrhosis.

The level of total bilirubin also helps to assess the excretory function of the liver. Indicators of total bilirubin help the doctor in the differential diagnosis of jaundice.

You can donate blood for the liver test in any department of the Center for Evidence-Based Medicine.

Method of determination

UV kinetic test, kinetic colorimetric and colorimetric photometric methods.

Test material

Venous blood serum.

Deadline

1 day

Readings

Analysis for ALT, AST, bilirubin and GGT should be performed when

• presence of signs of damage to the liver, gallbladder and bile ducts: pain or discomfort on the right side, nausea, impaired stool, discoloration of urine, yellowness of the skin and mucous membranes;
• preventive examination;
• observation of a patient whose treatment regimen contains drugs with a hepatotoxic effect (for example, methotrexate, tetracyclines, salicylates).

This study allows you to qualitatively assess the function of the liver and conduct an early diagnosis of its diseases.

Preparation for analysis

How to prepare for the analysis of ALT, AST, bilirubin, GGT?

Blood must be taken on an empty stomach, withstanding at least 8 hours without food. Water can be drunk normally. It is important to exclude physical and emotional overload, do not drink alcohol and energy drinks 24 hours before blood sampling. Do not smoke half an hour before the examination.

Synonyms: Liver function test, Laboratory liver panel, Liver function tests

Equipment: OLYMPUS AU/5800/680/480/-Beckman Coulter

8 (812) 600-42-00

It is recommended to donate blood on an empty stomach (at least 6-8 hours of fasting). Drinking – water, as usual. On the eve of the study, exclude: food, physical and emotional overload, alcohol and energy drinks. Stop smoking 1 hour before the study.

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Analysis available at these centers:

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Medical center on the street. Moiseenko, 5

Medical center on Prosveshcheniya avenue, 14k4

Medical center on the street. Savushkina, 14

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Medical center on Okhtinskaya alley, 4 (Murino, Leningrad region)

Laboratory terminal on the street. Pestelya, 25A

Laboratory terminal on the street. Oleko Dundicha, 8, building 2

Laboratory terminal on the street. Budapestskaya, 6

Medical center at Pulkovskoe shosse, 28A

Laboratory terminal at Nastavnikov Ave., 36k2

Laboratory terminal at Aleksandrovskaya Ferma avenue, 8

Medical center on Leninsky pr. , 88

Medical center on Kondratievsky prospect, 62k3

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Laboratory terminal at Kronverksky pr., 31 (official partner)

Clinic “PulkovoStom” on Pulkovskoye shosse, 26, building 6. (official partner)

Laboratory terminal on the street. Savushkina, 124 (official partner)

how to treat and protect the liver

Content

• 1 Effective ways to treat elevated AST and ALT in the liver
  • 1.1 Elevated levels of AST and ALT in the blood
  • 1.2 Causes of elevated AST and ALT levels in the blood 900 63
  • 1.3 Symptoms of elevated levels AST and ALT
  • 1.4 Diagnosis of elevated AST and ALT levels in the liver
  • 1.5 Treatment of elevated AST and ALT levels in the blood
    • 1.5.1 1. Treatment of the underlying disease
    • 1.5.2 2. Prescribing medications
    • 1.5.3 3. Dieting
    • 1.5.4 4. Avoiding exercise
    • 1.5.5 5. Taking vitamins and minerals
    • 1.5.6 6. Proper lifestyle
  • 1.6 Medicines for the treatment of elevated levels of AST and ALT
    • 1.6.1 1. Hepatoprotectors
    • 1.6.2 2. Antimetabolites
    • 1.6.3 3. Cytoprotectors

    90 062 1.6.4 4. Vitamins and anti-inflammatory drugs

  • 1. 7 Diet for Elevated AST and ALT Levels
  • 1.8 Liver Exercise
    • 1.8.1 Charging Exercise
    • 1.8.2 Exercise for Abdominal Pain

    90 062 1.8.3 Exercises for the respiratory system

    • 1.8. 4 Helpful Tips for Liver Health
  • 1.9 Herbal Medicine for Elevated AST and ALT
    • 1.9.1 Which herbal preparations help the liver?
  • 1.10 Liver protection
  • 1.11 Prevention of elevated liver AST and ALT levels
    • 1.11.1 Nutrition
    • 1.11.2 Exercise
    • 1.11.3 Stress avoidance
    • 1.11.4 Drug control 90 063
    • 1.11.5 Regular check-ups with a doctor
  • 1.12 Related videos:
  • 1.13 Q&A:
    • • 1.13.0.1 What can cause elevated levels of AST and ALT?
      • 1.13.0.2 What measures can be taken to protect the liver?
      • 1.13.0.3 Can elevated levels of AST and ALT be harmful to health?
      • 1.13.0.4 Is medication harmful to the liver?
      • 1. 13.0.5 What foods should be eliminated from the diet to restore the liver?
      • 1.13.0.6 What else helps protect the liver from damage?

Read the article on how to treat ast and alt liver with elevated levels. Find out what you need to do to restore the health of the liver and reduce the levels of ast and alt. Detailed expert advice and effective treatments.

Elevated levels of AST (aspartate aminotransferase) and ALT (alanine aminotransferase) are symptoms of liver dysfunction. These can be common infections, cirrhosis, biliary stasis, toxicosis, alcoholism and other disorders. But, it is worth noting that in some cases, the increase in the concentration of these enzymes may be associated with the use of drugs and dietary habits.

In this article, we’ll look at some helpful tips for protecting and improving liver health, as well as detailed treatments for elevated AST and ALT levels that will help keep your liver healthy and vibrant for years to come.

Elevated blood levels of AST and ALT

Aspartataminotransferaza (AST) and Alanintaminotransferaza (ALT) are enzymes that are present in liver cells. They are essential for transporting amino acids in the body, and their blood levels can be used as indicators of liver health. High levels of these enzymes can indicate liver damage or disease, including hepatitis, cirrhosis, and liver cancer.

There are several causes of elevated AST and ALT levels, including alcohol use, certain medications, viral infections, and autoimmune diseases. Levels can also rise with overuse of vitamins and overuse of nutritional supplements.

To treat high levels of AST and ALT, you must first find out the cause of the increase. If alcohol or drugs are used, stop using them. In the case of infections or autoimmune diseases, a doctor may prescribe medications to treat them. You can also recommend changing your diet and including healthier foods in your diet.

In addition to treatment, it is also necessary to protect the liver and prevent further damage. This may include actions such as eating more healthy foods, not smoking or drinking alcohol, using fewer drugs and supplements, and reducing stress levels.

• Healthy foods to protect the liver: vegetables, fruits, berries, nuts, fish, olive oil, green tea.
• Unhealthy foods to avoid: fatty and fried foods, soda, alcohol, food additives.
• Medicines and supplements that can increase AST and ALT levels: paracetamol, aspirin, vitamin A (large amounts), some types of antivirals.

Causes of elevated blood AST and ALT levels

AST and ALT levels can be elevated for various reasons. One of the most common is liver failure or liver disease. Some of the most common liver diseases that cause elevated levels of AST and ALT include hepatitis, cirrhosis, fatty liver, and liver toxicity.

Participation in intense exercise and sports may also cause a temporary increase in AST and ALT levels. However, if levels are elevated for several weeks or months, it may indicate the presence of liver disease or other health problems.

Symptoms of elevated levels of AST and ALT

AST and ALT are enzymes found in liver cells that play an important role in metabolism. These enzymes are usually found in small amounts in the blood, but if the liver is damaged, they can go beyond the normal range.

Signs of elevated levels of AST and ALT may include:

1. Pain in the right side of the abdomen;
2. Fatigue and weakness;
3. loss of appetite;
4. Discoloration of feces and urine;
5. Jaundice;
6. Edema of the legs;
7. Itching.

If you notice possible signs of liver damage, you should contact your doctor. Early contact with a specialist can help prevent complications and start treatment in a timely manner.

Diagnosis of elevated AST and ALT levels in the liver

AST (aspartate aminotransferase) and ALT (alanine aminotransferase) are enzymes that are found in the liver. Elevated levels of these enzymes in the blood may indicate problems with the liver.

A routine blood test is done to determine AST and ALT levels. Normal values ​​of AST and ALT levels differ depending on the sex and age of the person, so it may be necessary to consult a doctor to interpret the results of the analysis.

Elevated levels of AST and ALT may indicate various liver diseases such as jaundice, cirrhosis, hepatitis, alcoholic liver disease, liver cancer, and others. However, high levels of AST and ALT may also be associated with other diseases such as myocardial infarction or muscle disease.

• Additional tests, such as a blood test for bilirubin and alkaline phosphatase, as well as ultrasound and a liver biopsy, may be ordered to better diagnose liver problems.
• Seek medical attention if you experience symptoms associated with the liver, such as jaundice, liver enlargement, abdominal pain, nausea, vomiting, loss of appetite, and others.

Treatment of elevated blood AST and ALT levels

1. Treatment of underlying disease

Elevated levels of AST and ALT can result from various diseases such as hepatitis, cirrhosis, autoimmune hepatitis, and others. Treatment should begin with establishing the cause and treating the underlying disease.

2. Medications

In some cases, your doctor may prescribe medications to help reduce blood levels of AST and ALT. These may include drugs that improve liver function, as well as antiviral and anti-inflammatory drugs.

3. Dieting

Proper nutrition is essential for the treatment of elevated AST and ALT levels. It is necessary to exclude from the diet fatty, fried, fried and canned foods, as well as alcohol. It is recommended to reduce the intake of animal fats by replacing them with vegetable oils. It is also necessary to increase the consumption of fruits, vegetables, greens and protein foods.

4. Avoidance of physical activity

Strenuous physical activity should be avoided during treatment as it may aggravate the liver condition. Light exercise such as yoga, Pilates or walking is recommended.

5. Taking vitamins and minerals

To restore liver function, it is necessary to provide the body with all the necessary vitamins and minerals. The doctor may prescribe a vitamin complex containing vitamin C, E, B-groups, as well as minerals such as zinc and selenium.

6. A healthy lifestyle

Elevated levels of AST and ALT should stop smoking and drinking alcohol. It is also worth monitoring your weight and keeping it in the normal range so as not to create additional stress on the liver.

Sample menu for elevated AST and ALT EatingFood

Breakfast	Oatmeal with milk, scrambled egg, fresh seasonal fruit.
Snack	Apple/pear
Lunch	Steamed turkey cutlets, boiled rice porridge, fresh vegetable salad.
Snack	Green salad with olive oil
Dinner	Boiled fish, baked potatoes, steamed carrots

Medicines to treat elevated levels of AST and ALT

1. Hepatoprotectors

Hepatoprotectors are medicines that help protect and repair liver cells. They can decrease AST and ALT levels. Among the most commonly used hepatoprotectors are Ursodez, Essentiale Forte, Gepabene and others.

2. Antimetabolites

Antimetabolites are a group of drugs that can reduce the level of AST and ALT. They have their effect on liver cells that take part in metabolism. Popular drugs are Pentoxifylline, Methotrexate, Azathioprine, etc.

3. Cytoprotectors

Cytoprotectors are drugs that protect liver cells from destruction. They can reduce AST and ALT levels and improve liver metabolism. Cytoprotectors include Karsil, Liv.52, Hepatrombin, and others.

4. Vitamins and anti-inflammatory drugs

Vitamins and anti-inflammatory drugs can also help reduce AST and ALT levels. Vitamins A, C, and E can protect liver cells from destruction, and anti-inflammatory drugs such as Ibuprofen, Diclofenac, and Naproxen can reduce inflammation in the liver and lower AST and ALT levels.

Diet for elevated AST and ALT levels

Nutrition is an important factor in the treatment and protection of the liver. With elevated levels of AST and ALT, it is necessary to follow a diet that will reduce the load on the organ and improve its functioning.

First of all, it is necessary to reduce the consumption of fats, especially from animals. They can load the liver and lead to the development of fatty hepatosis. Fish, chicken, turkey, eggs, nuts, and seeds are good sources of protein to include in your diet.

In addition, it is important to increase your intake of vegetables and fruits, especially those that contain antioxidants such as vitamins C and E. For example, citrus fruits, berries, green tea, dark green vegetables – spinach, broccoli, cabbage, and kiwi, avocado, pomegranate, etc.

• Avoid fatty foods and fried foods.
• Limit sugar and sweets.
• Increase the amount of vegetables and fruits.
• Drinks containing caffeine and alcohol should be reduced or eliminated.
• Eat foods that help cleanse the liver – garlic, cauliflower, broccoli, spinach, beans, olive oil, etc.

It is important to monitor the caloric intake and not overeat. Do not forget about the diet – small but regular meals improve the functioning of the gastrointestinal tract and avoid overeating.

Foods to include in your diet Foods to avoid in your diet

Liver health exercises

Charging exercises

Charging is a great exercise in the morning, which helps to restore the whole body. Raise your arms up and stretch your upper limbs into an angle of 90 degrees. Sit up straight and fold your legs crosswise. Slowly tilt your body forward, trying to get as low as possible. Don’t forget to dry on the hem!

For the best functioning of the liver, it is necessary to work with the muscles of the body. The following exercise for the liver will have just such an effect. Embrace your knees and lower yourself down. Then gradually begin to raise your legs. When the pins are in a high position, straighten up sharply so that both hands can touch the feet.

Exercises for abdominal pain

If you suffer from abdominal pain, then you should turn to exercises that help reduce pressure in the internal organs and improve liver function. Start by simply raising your arm up and then begin tilting your body to the right and left. Do this approach several times.

Raise your legs at an angle of 30-40 degrees and hold in this position for several minutes, then return to the starting position. This exercise is also good because it works on the abdominal muscles.

Respiratory exercises

For better liver health, you need to do exercises that will improve your respiratory function. One of these exercises is to inhale exhale for 4 counts. At the same time, you should concentrate on breathing and not be distracted by other thoughts. The breath should be deep. As you exhale, the muscles relax and the respiratory function improves.

Liver Health Tips

• Avoid Alcohol and Smoking
• Drink plenty of purified water every day
• Maintain a healthy lifestyle, eat healthy food and exercise every day
• Eat more vegetables and fruits to get the necessary vitamins and minerals
• Watch your weight and avoid obesity

Phytotherapy with elevated levels of AST and ALT

Which herbal preparations help the liver?

Phytotherapy is an effective treatment for liver diseases. It includes the use of herbal preparations that help the body to normalize blood levels of AST and ALT.

It is also worth paying attention to preparations containing a plant complex. They usually include several herbal extracts that have a positive effect on the liver. These drugs include Hepatofit, Liv 52 and Enterosgel.

Herbs can greatly help the liver in detecting elevated AST and ALT levels. However, before starting treatment with herbal remedies, it is worth consulting with a doctor and choosing the right drug depending on the characteristics of the body.

Protecting the liver

The liver is one of the most important organs in our body. It performs many functions, including cleaning the blood of toxins and metabolic products. To protect the liver and keep it healthy, you should follow a few simple rules.

• Proper nutrition. Eat properly and avoid fatty, spicy, smoked, salty and sweet foods. Your diet should consist of healthy proteins, carbohydrates, fats, vitamins and minerals. If possible, drink plenty of water to help the liver clear toxins from the body.
• Refusal of bad habits. If you smoke or drink alcohol, it has a negative effect on the liver. Therefore, to protect it, you need to avoid these bad habits, or at least significantly reduce their level.
• Active lifestyle. Many liver problems can result from lack of physical activity. Therefore, try to move more, play sports, go for walks or do yoga. This will reduce the risk of various liver diseases.
• Check your performance. If you have to take tests, pay attention to the level of AST and ALT. If they are elevated, then this may signal the presence of some kind of liver problem. In this case, be sure to consult a doctor and undergo additional research.

By following these simple rules, you can protect your liver and keep it healthy for a long time.

Prevention of elevated levels of AST and ALT in the liver

Nutrition

Proper nutrition plays an important role in the prevention of elevated levels of AST and ALT in the liver. Eating foods rich in vitamins, minerals and antioxidants is recommended. Limiting your intake of fatty and fried foods, as well as alcohol, can greatly reduce your risk of liver problems.

Exercise

Regular exercise can greatly help prevent elevated levels of AST and ALT in the liver. They help improve blood circulation and metabolism, which positively affects the functioning of the liver.

Stress avoidance

Stress can lead to liver dysfunction, therefore it is recommended to avoid stressful situations and practice relaxation techniques.

Medication control

Consult your physician before taking any medication. Some medicines can damage the liver, so taking it should be under the supervision of a specialist.

Regular check-ups with your doctor

Regular check-ups with your doctor will help you identify possible liver problems at an early stage and take the necessary steps to treat or prevent them.

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Q&A:

What can cause elevated levels of AST and ALT?

Elevated levels of AST and ALT can be due to various causes, including alcoholic or viral hepatitis, certain medications, fatty liver, liver cancer, etc. To determine the specific cause of elevated levels of AST and ALT, it is necessary to consult a doctor and undergo an appropriate examination.

What measures can be taken to protect the liver?

To protect the liver, you need to watch your diet: eat more fruits and vegetables, limit the intake of fatty, fried and smoked foods, drink more water. You also need to exercise regularly, lead a healthy lifestyle, give up smoking and alcohol.

Can high levels of AST and ALT be harmful to health?

Yes, elevated levels of AST and ALT may indicate the presence of serious liver disease such as cirrhosis or liver cancer. Therefore, it is important to see a doctor and start treatment on time if AST and ALT levels are elevated.