Liver Panel Test – Testing.com

Test Quick Guide

A liver panel is a test with multiple measurements that help assess the health and function of the liver. The test is conducted with a blood sample that is normally taken from a vein in your arm.

A liver panel can be used to help diagnose and monitor liver diseases. It can also provide information about other health conditions that affect the liver, such as viral or alcoholic hepatitis. If you are taking medications that can impact the liver, the test results can determine whether side effects are occurring.

About the Test

Purpose of the test

The liver panel has many applications in medical care. While sometimes called a liver function test, it is better understood as a method of detecting liver disease and/or other health problems, including many that involve the liver.

Some of the specific ways that a liver panel can be used include:

• Diagnosis: Although a liver panel alone is not able to diagnose liver diseases, its measurements can help identify the type of problem if you have symptoms of liver conditions. The test can also help in the diagnostic process of other health concerns.
• Evaluating disease severity: A liver panel can help determine the extent of illness if you have known liver problems.
• Screening: You may have a liver panel as part of broader blood testing, known as the comprehensive metabolic panel, during routine medical checkups. If screening is abnormal, it may warrant more specific follow-up testing.
• Monitoring: Follow-up testing can provide information about how well treatment for liver problems is working. A liver panel can also monitor for side effects when you take medications that can impact liver health.

What does the test measure?

As a panel test, the liver panel involves multiple measurements. When the test is ordered, doctors can modify exactly which measurements to take.

For this reason, there is not a universal standard for what is measured on a liver panel. Nevertheless, some components of the test are more common. In most cases, a liver panel includes the following measurements:

• Aspartate aminotransferase (AST): This is a type of protein called an enzyme that is found in the liver as well as many muscles and organs.
• Alanine aminotransferase (ALT): This is an enzyme found primarily in the liver.
• Alkaline phosphatase (ALP): This is an enzyme found in the liver, bones, and other tissues in the body.
• Bilirubin: Bilirubin is a yellow-colored waste product that is the result of the normal breakdown of red blood cells. The liver works to remove bilirubin from the body.
• Albumin: Albumin is the most abundant protein in the blood and is made by the liver which prevents fluids from leaking out of the bloodstream.

Additional measurements may be added to a liver panel if the doctor believes they can provide more information to evaluate your situation. These measures may be tested on an initial liver panel, or included in repeat testing after an abnormal result on a previous test.

• Gamma-glutamyl transferase (GGT): An enzyme found in the liver and other organs.
• 5’ nucleotidase (5’-NT): An enzyme that exists in the liver and other organs.
• Total protein: Measures the sum of all proteins in the blood.
• Globulins: A class of proteins in the blood.
• Prothrombin time: A protein made by the liver that facilitates normal blood clotting and measures how long it takes for the blood to clot.
• Lactate dehydrogenase (LDH): An enzyme found in tissues throughout the body.

When should I get a liver panel?

There are many reasons you might decide to get a liver diagnostic test, or why a health care professional will order the lab test for you. This test can detect liver disease and other health problems involving the liver. You might be taking medications with liver damage as a side effect, and the test can measure whether the prescription is having a negative impact on your health. A liver panel can also be done as part of a metabolic panel during a routine medical visit.

A doctor might recommend a liver panel if you show common symptoms like jaundice (yellowing of the skin and eyes), nausea and vomiting, diarrhea, dark-colored urine, light-colored stool, or fatigue. The tricky thing is, aside from jaundice, these symptoms can easily be written off as “something else.”

That’s why it’s really important to consult with your doctor, who can advise whether a liver panel is necessary as part of an overall medical checkup or because of specific circumstances, such as monitoring cirrhosis or medication side effects.

Finding a Liver Panel

How can I get a liver panel?

Liver panel testing is performed in a medical setting such as a clinic, hospital, doctor’s office, or lab. Your doctor may order the liver panel, or you can purchase the test online and be referred to a nearby participating lab for the sample. Most liver panel testing happens with a blood draw and laboratory analysis. But there is a type of rapid, on-site point-of-care test that can measure certain components of the liver panel. It is not comprehensive.

Can I take the test at home?

There are at-home liver panel tests that can determine liver function by screening for proteins and enzymes like albumin, globulin, ALP, ALT, and GGT. These tests use a finger-prick sample and include materials to collect and send your specimen to the lab.

You can order a liver panel from home and get tested in a lab. Or, your doctor can prescribe the liver panel.

The at-home liver panel test is focused on liver function but does not provide the comprehensive results that an expanded liver panel does. It also tests for direct bilirubin and total bilirubin (waste produced by the liver), and AST, an enzyme found in the liver and other tissues.

How much does the test cost?

If you get a liver test ordered by a doctor, your insurance policy may cover the cost of the appointment and lab analysis. There may be a copay or deductible, however. If you order the test online, you can submit the receipt for potential reimbursement. You can find affordable liver panel testing that ranges in price from $39 to $79.

Before you order your own test from a lab or arrange a doctor-ordered liver panel, ask about costs, insurances accepted, copays, and deductibles. Be sure to refer to your doctor, lab, and health plan for details on test costs and insurance coverage.

Taking a Liver Panel Test

A liver panel requires drawing blood from a vein in your arm. The procedure is routine and performed in a medical office, clinic, hospital, or lab. There are some at-home tests available that involve a skin prick, but they are not as thorough as a liver panel from a lab.

Before the test

Plan on fasting for up to 12 hours before you take a liver panel test, only drinking water during this time. Also, be sure your doctor knows what medications you are taking because some prescription drugs and over-the-counter medications or dietary supplements can interfere with the test. Your doctor will provide specific guidelines on which medications and for how long to avoid them before a liver panel blood draw.

Not all liver panels require preparation. For example, an expanded liver panel you order online and go to a lab for testing does not require fasting. The comprehensive liver panel you can order online for lab testing does require fasting for 12 to 14 hours.

For at-home finger-prick liver tests, be sure to read the instructions carefully so you know whether the preparation is required.

During the test

A routine blood draw is all that is required to perform a liver panel. With a small needle, blood is drawn from a vein in your arm into a vial and analyzed by a lab. The phlebotomist will carefully clean the area first with antiseptic, and you might feel a sting when the needle is inserted or removed. You could experience mild bruising or soreness after the test like if you were getting blood drawn for any other medical panel. The entire process takes no more than five minutes.

At-home tests require a finger prick. The kit will include a lancet or small needle. You’ll get a test strip where you apply the blood drops, and then secure it in the provided packaging to send to the lab. It takes less than a minute to gather your sample and prepare the dry blood card for the lab. Remember, test kit instructions vary, so it’s important to read all instructions before obtaining your blood sample.

After the test

There are no restrictions after getting blood drawn for a liver panel, but if you fasted for 12 to 14 hours prior to the lab test, you will probably feel weak or fatigued. Consider bringing a snack for after your test. You can return to standard activities. Other than changing an adhesive bandage, there’s little to no recovery.

Liver Panel Test Results

Receiving test results

Depending on what type of liver panel you get, you can expect test results within one to two business days for an expanded panel that measures enzymes and proteins. It many take one to two days for a comprehensive panel that assesses enzymes and proteins to determine liver function, including GGT and LD. The comprehensive panel is also called hepatic function testing.

Lab result times can vary, so ask the clinician in advance how long it will take. Even at-home tests that use a finger prick to collect a blood sample will take a few business days from the time the lab receives your sample before you get results.

The speed of results can also depend on how you get them. Labs deliver results in a number of ways, including confidential phone calls, secure emails, or via an app.

Interpreting test results

Your liver panel test results will depend on the type of test. You will see some reference ranges to understand what levels are considered abnormal. Always discuss these results with a medical professional so you can ask questions and gain a clear understanding of the report, its information, and the next steps.

There are five common measures your liver panel test results will reveal.

• Bilirubin: Total bilirubin will show whether levels are raised due to a metabolic disorder or liver disease. In infants, it can indicate whether support is needed to address a liver that is not functioning properly.
• Albumin: This protein can be a marker for liver function and reduced albumin could indicate sepsis, inflammatory disorders, and other liver problems.
• ALP: Higher levels of ALP can be found in those with liver and bone disease.
• AST and ALT: These are liver enzymes and elevation can indicate liver-related issues. ALT can be an indicator of liver cell injury.
• GGT: This is used in the diagnosis and treatment of liver disease and in the evaluation of patients with alcoholism.

When test results are abnormal, doctors often look for certain patterns of abnormalities in the specific levels that were detected.

• Conditions involving acute or chronic liver damage often show disproportionate increases in ALT and AST compared to ALP.
• Bile duct obstruction is more often associated with a disproportionate increase in ALP compared to ALT and AST.
• Disorders affecting the normal processing of bilirubin may be demonstrated by elevated bilirubin with normal levels of ALT, AST, and ALP.
• Health conditions originating outside the liver are more common when abnormal albumin or prothrombin time occurs with otherwise normal results.

Your doctor will look at these test results and take into account your health, symptoms, and medical and family history. Any drugs you take are also considered since some medications can impact test results. Liver panel results are complex, so always review results with a medical professional who understands your case and can answer your questions. Here are some to ask:

• Was any part of my test result abnormal?
• If there was an abnormal result, can you explain what was found and what it may mean?
• If results were normal, will I need to have this testing again at any point in the future?
• Are there any follow-up tests that may be beneficial given my test results?

• CMP Blood Test (Comprehensive Metabolic Panel)
  Learn More
• Alanine Aminotransferase (ALT)
  Learn More
• Alkaline Phosphatase (ALP) Test
  Learn More
• Albumin Blood Test
  Learn More
• Total Protein, Albumin-Globulin (A/G) Ratio Test
  Learn More
• Bilirubin Test
  Learn More
• GGT Blood Test (Gamma Glutamyl Tranferase/Transpeptidase)
  Learn More
• Lactate Dehydrogenase (LDH) Test
  Learn More
• PT/INR Test (Prothrombin Time and International Normalized Ratio)
  Learn More

Resources

• National Library of Medicine: Liver Diseases
• National Institute of Diabetes and Digestive and Kidney Diseases: Liver Disease
• American Liver Foundation: Diagnosing Liver Disease

Sources

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Liver Function Test

Written by Matthew Hoffman, MD

• What Is a Liver Function Test?
• Why Are Liver Function Tests Done?
• Types of Tests and What They Measure
• How to Prepare for a Liver Function Test
• What Happens During a Liver Function Test?
• Liver Function Test Results
• Liver Function Test Risks
• More

A liver function test is one of a group of tests that check levels of certain enzymes and other proteins in your blood.

Some of the tests look for enzymes that you’d find in your blood only when your liver is damaged or has a disease. Others check that the organ is working the way it should.

Your liver does all kinds of work that’s crucial for your health. It helps break down food, clean your blood, make proteins, and store energy. If something goes wrong with it, you might have a number of symptoms, from yellow skin to slurred speech. That’s when you might need a liver test.

You might have this test to check for a liver disease such as hepatitis (an illness in which your liver swells and can cause serious issues). General symptoms of liver problems include:

• Lack of appetite
• Nausea or vomiting
• Weakness or feeling very tired
• Yellowish eyes or skin (jaundice)
• Dark urine or light-colored poop (less common)
• Swelling in your belly (less common)

Often, however, you don’t notice any symptoms.

Your doctor may order a liver test if you’re more likely to have liver damage or disease, like if you:

• Drink heavily or have an alcohol use disorder
• Have a family member with liver disease
• Are very overweight, especially if you also have diabetes or high blood pressure
• Take medicine that can harm your liver
• Have gallbladder disease or anemia

The liver test can also help your doctor learn whether an illness is getting worse or how well treatment is working.

There are a number of liver tests, with lots of complex names. Some common ones include:

• Alanine transaminase (ALT) test. ALT is an enzyme that helps break down proteins and is found mainly in your liver. High levels in your blood could mean you have liver damage.
• Alkaline phosphatase (ALP) test. ALP is an enzyme in your liver, bile ducts, and bone. You might have high levels if you have liver damage or disease, a blocked bile duct, or bone disease.
• Albumin and total protein test. Your liver makes two main proteins: albumin and globulin. Low levels might mean damage or disease. Keep in mind that your immune system also makes globulin.
• Aspartate transaminase (AST) test. AST is another enzyme in your liver. High blood levels could be a sign of damage or disease.
• Bilirubin test. Your body makes bilirubin when it breaks down red blood cells. Usually, your liver cleans bilirubin out of your body. If you have high levels in your blood, a problem called jaundice, you may have liver damage.
• Gamma-glutamyltransferase (GGT) test. High levels of the GGT enzyme could point to liver or bile duct damage.
• Prothrombin time (PT) test. This test measures how long it takes your blood to clot. If it takes a long time, that could be a sign of liver damage. Medications that thin your blood, such as warfarin (Coumadin), can also lead to a longer PT. You probably won’t have this test until you have had other liver tests.

Make sure to tell your doctor about any medicines you’re taking, including over-the-counter medications and herbal supplements. They may tell you to stop eating the night before the test.

Your doctor uses a thin needle to take a small amount of blood, usually from your arm near your elbow. You’ll feel a pinch or stinging when the needle goes in.

If there is liver damage, you’ll probably have these tests more than once over a few days or weeks. Your doctor can look at how levels change to be sure of your condition.

If you get your test at a clinic that has a lab on-site, you can get results in a few hours. If not, it might take a few days.

The results usually show normal values for the specific test, along with your numbers. Keep in mind that what’s normal can vary with different labs. It also depends on whether you’re male or female.

If your results aren’t normal, you’ll probably get more tests.

By itself, a liver test can’t tell for sure that you have a certain illness. Your doctor can help you understand what your results mean.

Liver function tests are generally safe, with few risks. You may have some soreness or a bruise where the blood is taken. Call your doctor if it doesn’t get better after a couple of days.

Top Picks

Liver tests.

Checking the main “filter” of the body: why and what indicators should be monitored

The human liver is not only an indispensable main “filter” of the body, but also its main “laboratory”. With the help of its working cells (hepatocytes), this organ performs hundreds of different functions. The liver constantly supplies many different substances into the blood, so even the slightest violation of the liver function entails a change in the composition of the blood. And if you do a blood test for certain markers, you can get a clear picture of the state of the liver. We now describe these analyzes in more detail.

The numbers describing the composition of the blood are biochemical indicators. Among these indicators, there are those in which certain changes always indicate changes in liver function – namely, functions, and not structures (structural changes are monitored in other ways, such as ultrasound). Therefore, these tests are called “liver function tests” (LFTs) or simply “liver tests”.

When should liver tests be done?

If nothing bothers you, you can donate blood for this test every year during a routine medical examination. Also, liver function tests are necessarily examined during pregnancy, before surgical interventions, before and during courses of treatment for certain diseases that involve the use of potent drugs.

Mandatory liver test is required in the presence of one or more of the following symptoms: These sensations usually manifest as a slight pulling pain and/or tingling. Especially noticeable when laughing, sneezing, coughing, screaming, tilting to the side, lifting heavy objects. They can also affect after eating fatty, fried, spicy or smoked foods;

bad taste in the mouth , coppery bitterness, dryness, astringent sensation. This can dull the taste, and the usual food can cause rejection up to vomiting;

The last set of symptoms indicates the presence of serious liver disease, including hepatitis.

Where can I have a liver test?

Donate blood for liver function tests in the departments of the all-Ukrainian network of laboratories “MedLab”. The laboratory offers the following “liver” packages:

• Package No. 970 “Liver tests No. 2” – alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase, g-glutamyl transpeptidase, total protein, total bilirubin.
• Package No. 10 “Liver tests” – bilirubin (total, direct, indirect), alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase, total protein, g-glutamyl transpeptidase;
• Liver Assessment Package #54, which includes analyzes for protein fractions (albumin, α-1-globulins, α-2-globulins, β-1-globulins, γ-globulins, A / G coefficient), thymol test, total protein, lactate dehydrogenase (LDH), alkaline phosphatase, gamma-glutamyl transpeptidase (GGT), alanine aminotransfer for (ALT), aspartate aminotransferase (AST), total bilirubin, direct, indirect.

Test results will be ready:

• Package #10 Oven Samples and Package #970 Oven Samples #2 — within 1 working day.
• Package No. 54 “Assessment of the state of the liver” – within 2 working days.

How do I prepare for a liver test?

To achieve the most reliable liver test results, follow these guidelines:

1. Test strictly on an empty stomach. The liver is involved in the processes of digestion, and the food itself also affects liver performance. Therefore, you should not eat at least 8 hours before taking liver tests (during this time, you should also not drink anything but pure water). In addition, 3 days before delivery, you need to give up spicy and fatty foods.
2. Do not drink alcohol for 3 days prior to testing. Even a minimal dose of alcohol puts a heavy strain on the liver, changes the composition of the blood and its properties (including clotting and some “liver” indicators).
3. Do not smoke for 12 hours before testing. Substances that enter the blood from cigarette smoke can also change the composition of the blood and affect the results of the study.
4. Avoid strenuous activities , including “serious” sports, for 3 days prior to analysis. By the way, during this period it is recommended to protect yourself not only from physical, but also from psycho-emotional overstrain, stress factors, and also observe the correct sleep pattern.
5. If you are taking any medications, stop taking them if possible. Even harmless vitamins can distort the result of a biochemical “liver” analysis. Therefore, any medications should ideally be discontinued at least a week before the FPP is taken. If this is not possible, then it is necessary to warn the doctor in advance about the medicines that you are taking.

IMPORTANT! Liver tests, like any other analysis, can be performed in different laboratories using different methods, equipment and using different units of measurement. Therefore, when a doctor prescribes a second study to evaluate the effectiveness of treatment, it is necessary to conduct it in the same lab as where liver tests were taken earlier.

Liver tests, biochemical blood tests in Kyiv

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Study code:
124

Execution time:
1-3 working days

Material:
serum

Price:

450
UAH

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by price:
UAH 450.00 Add to cart

Preparation

A mandatory requirement is the mode of complete refusal of food on the day of blood donation for analysis (in the evening of the previous day, a light dinner is recommended). When donating venous blood, it is necessary to exclude factors that affect the results of the research: physical stress (running, climbing stairs), emotional arousal. Therefore, before the procedure, you should rest for 10-15 minutes in the waiting room, calm down. You should not donate blood after exposure to X-rays (“X-ray”), physiotherapy procedures. Taking into account the daily rhythms of changes in blood parameters, it is advisable to take samples for repeated studies at the same time.

Research is accepted from Monday to Saturday, in all branches of the Dneprolab CLD in Kyiv.

Description

Liver tests – a biochemical study of blood, which includes the quantitative determination of the level of certain enzymes and the concentration of organic substances. Indicators that assess the functional and structural state of the liver and hepatobiliary system (including the gallbladder and biliary tract) include:

• Activity of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) enzymes.
• Activity of alkaline phosphatase (AP) and gamma-glutamyltransferase (GGT) enzymes.
• The level of bilirubin in the blood, including its fractions (direct and indirect bilirubin).
• The level of total protein in the blood.

Thanks to these indicators, it is possible to determine the degree of damage to hepatocytes (liver cells) by a pathological process, the state of its excretory and synthetic functions.

Liver tests are included in the standard blood chemistry test along with kidney tests.

Where can I take

Ukraine, Kiev, Vyshgorodskaya street, 21

st. Vyshgorodskaya, 21

Phones:

(044) 29-099-29

Viber (095) 29-099-29

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Ukraine, Kyiv, st. Peter Zaporozhets, 26

Petra Zaporozhets, 26

Phones:

(044) 29-099-29

viber (095) 29-099-29

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Ukraine, Kiev, st. Popudrenko, 7

Hetman Polubotka, 7 (Popudrenko, 7)

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viber (095) 29-099-29

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Ukraine, Cherkasy, 30th anniversary of the Victory 16

Cherkasy, 30th anniversary of the Victory 16

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(073)738-38-45

(044)29-099-29

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Ukraine, Brovary, st. Gagarina, 20b

Brovary, Heroes of Ukraine, 20 B (Gagarina, 20 B)

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(044)29-099-29

viber (095)29-099-29

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Ukraine, Kiev, Bazhana Avenue, 12

Bazhana Avenue, 12

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Ukraine, Kyiv, st. Kurnatovsky, 7

Evstafiya Dashkevich, 7 (Kurnatovsky, 7 children’s department)

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(044) 29-099-29

viber (095) 29-099-29

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Ukraine, Kiev, Mayakovskogo avenue, 20

Chervonoi Kalini avenue, 20 (Mayakovskogo avenue, 20)

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Ukraine, Kiev, st. Metropolitan Andrey Sheptytsky, 5

Sheptytsky (Lunacharsky), 5

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viber (095)29-099-29

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Ukraine, Kiev, st. Yakubovsky, 6

Heroes of Mariupol, 6 (Yakubovsky, 6)

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(044)29-099-29

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Ukraine, Kiev, 27 Geroev Stalingrad Ave.

27 Vladimir Ivasyuk Ave. (27 Geroev Stalingrad Ave.)

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Ukraine, Fastov, st. L. Tolstoy, 28

Fastov, Heroes of Chernobyl, 24 (Tolstoy, 24)

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(04565) 5-14-08

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Schedule:

Ukraine, Cherkasy, Chernovola 1

Cherkasy, Chernovola 1

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(073)056-59-27

(044)29-099-29

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Ukraine, Kiev, st. Velyka Zhitomirskaya, 14

Velyka Zhitomirskaya, 14

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(044)29-099-29

viber (095)29-099-29

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Ukraine, Kiev, Koltsov boulevard, 14Zh

Koltsov boulevard, 14Zh

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Ukraine, Kyiv, st. Dekabristov, 5

Bratsva Tarasovtsy, 5 (Dekabristov, 5)

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Ukraine, Kyiv, st. Kharkiv highway, 56

Kharkov highway, 56

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Ukraine, Sofievskaya Borshchagovka, st. Voloshkova, 30

Voloshkova, 30, Sofiyivska Borshchagovka

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(044) 29-099-29

viber (095) 29-099-29

Working hours:

Ukraine, Kiev, Trostyanetskaya, 8D

Trostyanetskaya, 8D (children’s nurse)

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(044)29-099-29

viber (095)29-099-29

Working hours:

Ukraine, Kyiv, st. Zakrevskogo, 42A

Zakrevskogo, 42A

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(044) 29-099-29

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Ukraine, Chernihiv, Rokossovsky street, 49

Chernihiv, Levko Lukyanenko avenue, 49 (Rokosovsky 49)

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(044) 29-099-29

viber (095) 29-099-29

Working hours:

Ukraine, Kiev, ave. Pavel Tychyny, 3

Tychyny, 3

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(044)29-099-29

(095)29-099-29

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Ukraine, Chernihiv, Mazepy street, 4

Chernihiv Mazepa, 4

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(044) 29-099-29

viber (095) 29-099-29

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Ukraine, Fastov, Kommunalny lane, 7A

Fastov, Kommunalny lane, 7A

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(044)29-099-29

(095)29-099-29

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Ukraine, Cherkasy, st. Baydy Vyshnevetsky 36/1

Cherkasy, st. Baidy Vyshnevetsky 36/1

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(073)750-16-08

(044)29-099-29

Working hours:

Ukraine, Kiev, Petra Zaporozhtsa, 26A

Petra Zaporozhtsa, 26A

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(044) 29-099-29

Viber (095) 29-099-29

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Ukraine, Kiev, Yaltinskaya street, 8

Yaltinskaya street, 8

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(044) 29-099-29

viber (095) 29-099-29

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Ukraine, Kiev, st. Garmatnaya, 37A

Garmatnaya, 37A

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(044)29-099-29

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Working hours:

Ukraine, p. Hatne, st. Optimisticnaya, 1,

st. Optimistic, 1, p. Hatnoe

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(044)29-099-29

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Working hours:

Ukraine, Kiev, Piterskaya street, 16

Londonskaya, 16 (Piterskaya, 16)

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(044)29-099-29

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Working hours:

Ukraine, Fastov, st. Shevchenko 53B

Fastov, Shevchenko, 53B

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(044)29-099-29

viber (095)29-099-29

Working hours:

Ukraine, Kiev, street Enthusiasts, 47

st. Entuziastov, 47

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(044)29-099-29

viber (095)29-099-29

Working hours:

Ukraine, p.