What are the primary uses of thiothixene. How does thiothixene work in treating mental disorders. What are the most common side effects of thiothixene. How should thiothixene be taken for optimal effectiveness. What precautions should be considered when using thiothixene.

Understanding Thiothixene: A Comprehensive Overview

Thiothixene is a psychiatric medication classified as an antipsychotic drug. It is primarily used to treat certain mental and mood disorders, with a focus on schizophrenia. This powerful medication works by restoring the balance of natural substances in the brain, particularly dopamine, which plays a crucial role in regulating mood and behavior.

Primary Uses of Thiothixene

The main purpose of thiothixene is to help individuals with schizophrenia and related disorders. It aids patients in:

• Thinking more clearly
• Feeling less nervous
• Participating more effectively in everyday life
• Reducing aggression and self-harm tendencies
• Decreasing hallucinations (auditory and visual)

The Mechanism of Action: How Thiothixene Works

Thiothixene belongs to a class of drugs known as antipsychotics. Its effectiveness in treating mental disorders stems from its ability to influence neurotransmitter activity in the brain. How does thiothixene achieve this? The medication primarily targets dopamine receptors, helping to restore balance in the brain’s chemical messaging system.

By modulating dopamine levels, thiothixene can alleviate various symptoms associated with schizophrenia and other psychotic disorders. This includes reducing hallucinations, delusions, and disorganized thinking, which are hallmark symptoms of these conditions.

Proper Administration and Dosage Guidelines

Administering thiothixene correctly is crucial for its effectiveness and safety. How should patients take this medication? Here are the key points to remember:

• Thiothixene can be taken orally with or without food
• The typical dosing schedule is 1 to 3 times daily
• Dosage is individualized based on age, medical condition, and treatment response
• To minimize side effects, doctors often start with a low dose and gradually increase it
• Consistency is key – take the medication at the same time(s) each day

Is there a specific duration for thiothixene treatment? While some effects may be noticeable soon after starting the medication, it can take 2 to 3 weeks to experience the full benefits. Patients should not discontinue thiothixene without consulting their healthcare provider, as sudden cessation can lead to worsening of symptoms or withdrawal effects.

Potential Side Effects and Risks of Thiothixene

As with any medication, thiothixene can cause side effects. While not everyone experiences these, it’s important to be aware of potential adverse reactions. What are the most common side effects of thiothixene?

• Drowsiness
• Dizziness
• Lightheadedness
• Dry mouth
• Blurred vision
• Constipation
• Sleep disturbances

More serious side effects, though less common, can include:

• Muscle and nervous system problems (extrapyramidal symptoms)
• Tardive dyskinesia (involuntary muscle movements)
• Neuroleptic malignant syndrome (a rare but severe reaction)
• Changes in prolactin levels affecting sexual function and fertility

Patients should report any persistent or worsening side effects to their healthcare provider promptly.

Special Precautions and Warnings for Thiothixene Use

Are there any specific groups who should exercise caution when using thiothixene? Yes, certain populations need to be particularly careful:

• Older adults with dementia: There may be an increased risk of serious side effects, including heart problems and pneumonia
• Individuals with a history of cardiovascular issues
• Patients with liver or kidney disease
• People with a history of seizures
• Individuals with low white blood cell counts

It’s crucial to inform your healthcare provider about all medical conditions and medications before starting thiothixene treatment.

Interactions and Contraindications

Thiothixene can interact with various substances and medications, potentially altering its effectiveness or increasing the risk of side effects. What are some key interactions to be aware of?

• Alcohol: Can enhance the sedative effects of thiothixene
• Other CNS depressants: May increase drowsiness and dizziness
• Certain antidepressants: Can lead to increased side effects
• Blood pressure medications: May require dose adjustments
• Parkinson’s disease medications: Can potentially reduce their effectiveness

Always provide your healthcare provider with a complete list of all medications, supplements, and herbal products you’re taking to avoid potential interactions.

Long-term Effects and Monitoring

Long-term use of thiothixene requires careful monitoring to ensure ongoing safety and effectiveness. What aspects of health should be regularly assessed during thiothixene treatment?

• Mental health status and symptom improvement
• Metabolic parameters (weight, blood sugar, lipid levels)
• Cardiovascular health
• Neurological function, particularly for signs of tardive dyskinesia
• Liver and kidney function
• Blood cell counts

Regular check-ups and open communication with healthcare providers are essential for managing long-term thiothixene therapy effectively.

Thiothixene in the Context of Overall Mental Health Treatment

While thiothixene can be a valuable tool in managing schizophrenia and related disorders, it’s important to view it as part of a comprehensive treatment approach. How does thiothixene fit into the broader picture of mental health care?

Effective management of conditions like schizophrenia often involves a multifaceted approach:

1. Medication management (including thiothixene and potentially other drugs)
2. Psychotherapy (such as cognitive-behavioral therapy)
3. Social skills training
4. Family education and support
5. Occupational therapy
6. Lifestyle modifications (diet, exercise, stress management)

Thiothixene can help stabilize symptoms, allowing individuals to engage more effectively in other therapeutic interventions and improve their overall quality of life.

Comparing Thiothixene to Other Antipsychotics

How does thiothixene compare to other antipsychotic medications? Thiothixene is considered a first-generation (typical) antipsychotic. While effective, it may have a different side effect profile compared to newer, second-generation (atypical) antipsychotics. The choice between thiothixene and other antipsychotics depends on various factors, including:

• Individual patient response
• Side effect tolerability
• Specific symptom presentation
• Comorbid conditions
• Cost and accessibility

Healthcare providers consider these factors carefully when prescribing thiothixene or alternative medications.

Patient Education and Empowerment

Educating patients about thiothixene is crucial for ensuring treatment success and safety. What key points should patients understand about their medication?

• The importance of adhering to the prescribed dosage and schedule
• Potential side effects and when to seek medical attention
• The need for regular follow-up appointments and monitoring
• Lifestyle modifications that may enhance treatment effectiveness
• The importance of not abruptly discontinuing the medication

Empowering patients with knowledge about their treatment can improve adherence and outcomes. Healthcare providers should encourage open dialogue and address any concerns or questions patients may have about thiothixene.

Supporting Medication Adherence

Adherence to thiothixene treatment is crucial for its effectiveness. How can patients and caregivers ensure consistent medication use?

• Use pill organizers or reminder apps
• Integrate medication into daily routines
• Educate family members or caregivers about the importance of adherence
• Address side effects promptly with healthcare providers
• Regularly discuss the benefits of treatment to maintain motivation

By implementing these strategies, patients can maximize the benefits of thiothixene while minimizing potential risks associated with inconsistent use.

Future Directions and Research in Antipsychotic Treatments

While thiothixene has been a valuable tool in treating schizophrenia and related disorders, ongoing research continues to explore new avenues for antipsychotic treatments. What are some emerging areas of study in this field?

• Development of more targeted antipsychotic medications with fewer side effects
• Exploration of personalized medicine approaches to optimize treatment selection
• Investigation of novel drug delivery methods for improved efficacy and adherence
• Research into combination therapies that may enhance overall treatment outcomes
• Studies on early intervention strategies to potentially prevent or mitigate the progression of psychotic disorders

These research directions hold promise for improving the treatment landscape for individuals with schizophrenia and related conditions, potentially offering more effective and tolerable options in the future.

The Role of Genetics in Antipsychotic Treatment

Genetic factors can influence how individuals respond to antipsychotic medications like thiothixene. How might genetic testing impact future treatment approaches? Pharmacogenomic research is exploring the potential for tailoring antipsychotic treatments based on an individual’s genetic profile. This could lead to:

• More precise medication selection
• Optimized dosing strategies
• Reduced trial-and-error in finding effective treatments
• Minimized risk of adverse reactions

While still in its early stages, this field of study holds promise for enhancing the efficacy and safety of antipsychotic treatments, including thiothixene.

Navigating Mental Health Resources and Support

For individuals prescribed thiothixene, accessing comprehensive mental health support is crucial. What resources are available to support patients and their families?

• Mental health advocacy organizations providing education and support
• Peer support groups for individuals with similar experiences
• Online forums and communities for sharing information and coping strategies
• Local community mental health centers offering various services
• Crisis hotlines for immediate support during difficult times

Utilizing these resources can complement medical treatment and provide valuable emotional and practical support throughout the treatment journey.

Addressing Stigma and Promoting Mental Health Awareness

Individuals taking medications like thiothixene may face stigma related to mental health conditions. How can we address this issue and promote better understanding?

• Educating the public about mental health conditions and their treatments
• Encouraging open conversations about mental health in various settings
• Supporting anti-stigma campaigns and initiatives
• Sharing personal stories of recovery and success
• Advocating for policies that support mental health treatment and research

By fostering a more informed and compassionate society, we can create an environment where individuals feel supported in seeking and maintaining treatment with medications like thiothixene.

Thiothixene Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

Warnings:

There may be a slightly increased risk of serious, possibly fatal side effects (such as heart failure, fast/irregular heartbeat, pneumonia) when this medication is used by older adults with dementia. This medication is not approved for the treatment of dementia-related behavior problems. Discuss the risks and benefits of this medication, as well as other effective and possibly safer treatments for dementia-related behavior problems, with the doctor.

Warnings:

There may be a slightly increased risk of serious, possibly fatal side effects (such as heart failure, fast/irregular heartbeat, pneumonia) when this medication is used by older adults with dementia. This medication is not approved for the treatment of dementia-related behavior problems. Discuss the risks and benefits of this medication, as well as other effective and possibly safer treatments for dementia-related behavior problems, with the doctor.

… Show More

Uses

Thiothixene is used to treat certain mental/mood disorders (such as schizophrenia). This medicine helps you to think more clearly, feel less nervous, and take part in everyday life. It can reduce aggression and the desire to hurt yourself/others. It may also help to decrease hallucinations (such as hearing/seeing things that are not there). Thiothixene is a psychiatric medication (antipsychotic-type) that works by helping to restore the balance of certain natural substances (such as dopamine) in the brain.

How to use Thiothixene

Take this medication by mouth with or without food as directed by your doctor, usually 1 to 3 times daily.

Dosage is based on your age, medical condition, and response to treatment. To reduce your risk of side effects such as drowsiness and shaking (tremor), your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor’s directions carefully.

Take this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time(s) each day.

Although you may notice some medication effects soon after starting, for some conditions it may take 2 to 3 weeks before you get the full benefit of this drug.

Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Also, you may experience symptoms such as severe confusion and hallucinations. To prevent these symptoms while you are stopping treatment with this drug, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details. Report any new or worsening symptoms right away.

Tell your doctor if your condition does not improve or if it worsens.

Side Effects

See also Warning section.

Drowsiness, dizziness, lightheadedness, dry mouth, blurred vision, constipation, and trouble sleeping may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Dizziness and lightheadedness can increase the risk of falling. Get up slowly when rising from a sitting or lying position.

This drug may cause muscle/nervous system problems (extrapyramidal symptoms-EPS). Your doctor may prescribe another medication to decrease these side effects. Tell your doctor right away if you notice any of the following side effects: stiff muscles, severe muscle spasms/cramping (such as twisting neck, arching back, eyes rolling up), restlessness/constant need to move, shaking (tremor), slow/shuffling walk, drooling/trouble swallowing, mask-like expression of the face.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: fainting, confusion, depression/suicidal thoughts, difficulty urinating, easy bruising/bleeding, signs of infection (such as sore throat that doesn’t go away, fever), severe stomach/abdominal pain, seizures.

This medication may cause a condition known as tardive dyskinesia. In some cases, this condition may be permanent. Tell your doctor right away if you develop any involuntary/repetitive muscle movements such as lip smacking/puckering, tongue thrusting, chewing, or finger/toe movements.

In rare cases, thiothixene may increase your level of a certain chemical made by the body (prolactin). For females, this increase in prolactin may result in unwanted breast milk, missed/stopped periods, or difficulty becoming pregnant. For males, it may result in decreased sexual ability, inability to produce sperm, or enlarged breasts. If you develop any of these symptoms, tell your doctor right away.

This medication may rarely cause a very serious condition called neuroleptic malignant syndrome (NMS). Get medical help right away if you have any of the following symptoms: fever, muscle stiffness/pain/tenderness/weakness, severe tiredness, severe confusion, sweating, fast/irregular heartbeat, dark urine, signs of kidney problems (such as change in the amount of urine).

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

See also Warning section.

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood problems (such as low red/white/platelet blood cell counts), a certain eye condition (glaucoma), heart problems (such as fast/irregular heartbeat, low blood pressure), liver disease, breast cancer, brain disorder/tumor/injury, drug/alcohol/substance abuse, Parkinson’s disease, seizures, a certain severe reaction to other antipsychotic-type medications (neuroleptic malignant syndrome-NMS), slow movement of the gut/intestines (such as chronic constipation, intestinal blockage), difficulty urinating (such as due to prostate problems).

This drug may make you dizzy or drowsy or blur your vision. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness.

Before having surgery or imaging procedures (such as certain X-rays, CT scans) requiring the use of contrast dye (such as metrizamide), tell your doctor or dentist that you are using this medication and about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

This medication may make you sweat less, making you more likely to get heat stroke. Avoid doing things that may cause you to overheat, such as hard work or exercise in hot weather, or using hot tubs. When the weather is hot, drink a lot of fluids and dress lightly. If you overheat, quickly look for a place to cool down and rest. Get medical help right away if you have a fever that does not go away, mental/mood changes, headache, or dizziness.

Older adults may be more sensitive to the side effects of this drug, especially dizziness, lightheadedness, drowsiness, confusion, constipation, trouble urinating, extrapyramidal symptoms (EPS), and tardive dyskinesia (TD) (see Side Effects). Dizziness, lightheadedness, drowsiness, and confusion can increase the risk of falling.

During pregnancy, this medication should be used only when clearly needed. Babies born to mothers who have used this drug during the last 3 months of pregnancy may rarely develop symptoms including muscle stiffness or shakiness, drowsiness, feeding/breathing difficulties, or constant crying. If you notice any of these symptoms in your newborn especially during their first month, tell the doctor right away.

Since untreated mental/mood problems (such as schizophrenia) can be a serious condition, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Some products that may interact with this drug include: anticholinergic/antispasmodic drugs (such as atropine, dicyclomine, scopolamine), lithium, drugs that increase the amount of dopamine in your body (such as cabergoline, levodopa, pergolide, ropinirole), drugs that lower blood pressure (such as guanethidine, alpha blockers like prazosin).

Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcohol, marijuana (cannabis), antihistamines (such as cetirizine, diphenhydramine), drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants, and opioid pain relievers (such as codeine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

Does Thiothixene interact with other drugs you are taking?

Enter your medication into the WebMD interaction checker

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe drowsiness/dizziness, inability to wake up (coma).

Do not share this medication with others.

Lab and/or medical tests (such as complete blood count, eye exams) should be done while you are taking this medication. Keep all medical and lab appointments. Consult your doctor for more details.

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Images

thiothixene 5 mg capsule

Color: caramel,whiteShape: oblongImprint: 016 Novitium

This medicine is a caramel white, oblong, capsule imprinted with “016” and “Novitium”.

thiothixene 2 mg capsule

Color: yellow,caramelShape: oblongImprint: 015 Novitium

This medicine is a caramel white, oblong, capsule imprinted with “016” and “Novitium”.

thiothixene 1 mg capsule

Color: caramel,blueShape: oblongImprint: 014 Novitium

This medicine is a caramel white, oblong, capsule imprinted with “016” and “Novitium”.

thiothixene 10 mg capsule

Color: peach,caramelShape: oblongImprint: 017 Novitium

This medicine is a caramel white, oblong, capsule imprinted with “016” and “Novitium”.

thiothixene 5 mg capsule

Color: caramel,whiteShape: oblongImprint: MYLAN 3005 MYLAN 3005

This medicine is a caramel white, oblong, capsule imprinted with “016” and “Novitium”.

thiothixene 2 mg capsule

Color: yellow,caramelShape: oblongImprint: MYLAN 2002 MYLAN 2002

This medicine is a caramel white, oblong, capsule imprinted with “016” and “Novitium”.

thiothixene 10 mg capsule

Color: peach,caramelShape: oblongImprint: MYLAN 5010 MYLAN 5010

This medicine is a caramel white, oblong, capsule imprinted with “016” and “Novitium”.

thiothixene 1 mg capsule

Color: caramel,powder blueShape: oblongImprint: MYLAN 1001 MYLAN 1001

This medicine is a caramel white, oblong, capsule imprinted with “016” and “Novitium”.

thiothixene 1 mg capsule

Color: caramel,blueShape: oblongImprint: AA10A

This medicine is a caramel white, oblong, capsule imprinted with “016” and “Novitium”.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Thiothixene Definition & Meaning | Merriam-Webster Medical

thio·​thix·​ene

ˌthī-ō-ˈthik-ˌsēn 

: an antipsychotic drug C₂₃H₂₉N₃O₂S₂ used especially in the treatment of schizophrenia

see navane

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Thiothixene use, side effects and precautions / psychopharmacology

Schizophrenia is one of the mental illnesses with the most variability in symptoms and degrees of damage that exist. Thus, the variety of drugs for its treatment should also be very wide.

Thiothixene is an antipsychotic drug Traditionally used, almost exclusively, for the treatment of schizophrenia. In this article, we will discuss its uses and side effects, as well as precautions to be taken by patients who consume it.0003

• Related article: “Psychotropic drugs: drugs that act on the brain

What is thiothixene?

Thiothixene is an antipsychotic drug in the family of typical antipsychotics. Popularly known under the trade name Navane , thiothixenos acts by blocking D2 dopaminergic receptors.

In particular, the action of thiothixene focuses on blocking dopaminergic receptors at the level of the cortico-meso-limbic pathway. This obstruction of dopamine receptors alters levels of it, transforming the person’s behavior. In particular, thiothixene prevents over-stimulation of a person and contributes to the regulation of certain mental illnesses classified as psychotic.

• You may be interested in: “Types of antipsychotics (or neuroleptics)”

What disorders is it used for?

Thiothixene is used almost exclusively for the treatment of symptoms associated with a number of mental and psychiatric conditions such as schizophrenia .

This disorder covers a category of diagnoses characterized by severe perceptual alterations, lack of adaptation to the reality surrounding the patient, and a neuropsychological disorder that affects a large number of executive functions..

However, with the use of thiothixene, the patient will be able to think more clearly, reduce arousal levels and therefore better integrate into the environment and perform daily activities.

In addition, this antipsychotic helps reduce aggressive behavior and the desire or need to harm others or yourself. In the same way, while helping to restore mental balance, it also helps to reduce the number of hallucinations.

• Related article: “5 differences between psychosis and schizophrenia”

How is this done?

Thiothixene is sold in capsules in various concentrations or amounts to be administered depending on the severity of the patient’s symptoms. However, the healthcare professional will adjust the dose according to the specific needs of the patient.

Usually, to minimize possible side effects such as sedation or tremor, treatment with thiothixene will begin gradually , starting with a low dose of this and increasing it as the first weeks pass.

It is essential that the patient follow their physician’s instructions for the letter. Although it may take 2 or 3 weeks before the patient begins to feel the effects of thiothixene, the patient can never stop taking the drug or take more doses than directed without first consulting the doctor.

If the patient stops taking this drug suddenly, you run the risk of getting a number of symptoms like a feeling of acute confusion and very serious hallucinations. Thus, in case you have to complete the treatment, it should be done gradually and under the supervision of a doctor..

What are the side effects of it??

Like many other antipsychotic drugs, thiothixene includes a number of side effects for the patient which in some cases can cause serious trouble for the person.

These side effects can be divided into those that do not require medical attention and those that require medical attention as soon as possible.

In any case, if these side effects increase or prolong over time, it is necessary to inform the doctor about this dose adjustment.

Non-serious side effects

• illness
• vomiting
• constipation
• Weight gain
• Changes in the menstrual cycle
• Descent of desire and sexual behavior

Serious side effects

• dizziness 9Fever
• Muscle weakness
• Changes in vision
• Breathing problems
• Difficulty speaking and swallowing
• Changes in ability to urinate
• Changes in heart rate
• convulsions
• Muscle stiffness and/or spasms
• Lack of balance
• Difficulty walking
• Increased breast size in men and women
• Milk production outside lactation

What are the precautions should be taken when using them?

Before starting treatment, it is essential that the patient informs their doctor of any allergy, disease or special health condition they are experiencing that may interfere with the progress of treatment. .

There are a number of conditions or diseases that may be aggravated by the use of thiothixene. These are:

• Brain tumors or head injuries
• dementia
• Heart disease
• Blood changes
• Parkinson’s disease
• 9 0005 Kidney changes and liver

In the same way, the doctor should be aware of any drugs, vitamin supplements or natural complexes that the patient consumes both before and during treatment with thiothixene. Since they can cause a number of interventions with thiothixene and harm the human body.

Due to its sedative effect, thiothixene may cause drowsiness and dizziness in those who consume it. Therefore, those patients who perform activities such as driving or operating heavy machinery should suspend their activities or at least take special precautions during treatment.

Similarly, consumption of thiothixene during pregnancy and lactation may cause injury to the newborn, therefore its use should be limited to cases in which there is no alternative effective treatment. .

uses, side effects and precautions

Thiotomin: uses, side effects and precautions

psychopharmacology

June 23, 2023

Schizophrenia is one of the mental illnesses with the most variability in symptoms and degrees of impairment that exists. Therefore, the variety of drugs for its treatment should also be very wide.

Thiothixene is an antipsychotic Traditionally used, almost exclusively, for the treatment of schizophrenia. In this article, we will discuss its uses and side effects, as well as precautions to be taken by patients who consume it.

• Related article: “Psychotropic drugs: drugs that act on the brain

What is thiothixene?

Thiothixene is an antipsychotic drug in the typical antipsychotic family. Popularly known under the brand name Navane , thiothixenos acts by blocking dopaminergic D2 receptors.

In particular, the action of thiothixene focuses on blocking dopaminergic receptors at the level of the corticomeso-limbic pathway. This obstruction of dopamine receptors alters levels of it, transforming the person’s behavior. In particular, thiothixene prevents over-stimulation of a person and facilitates the regulation of certain mental illnesses classified as psychotic.

• You may be interested in: “Types of antipsychotics (or neuroleptics)”

What disorders is it used for?

Thiothixene is used almost exclusively for the treatment of symptoms associated with a number of mental and psychiatric conditions such as schizophrenia .

This disorder covers a category of diagnoses that are characterized by severe changes in perception, lack of adaptation to the reality surrounding the patient, and neuropsychological disorganization that affects a large number of executive functions.

However, with the use of thiothixene, the patient will be able to think more clearly, reduce their level of arousal and, therefore, better integrate into the environment and perform daily activities.

In addition, this antipsychotic helps reduce aggressive behavior and the desire or need to harm others or yourself. In the same way, while helping to restore mental balance, it also helps to reduce the number of hallucinations.

• Related article: “5 differences between psychosis and schizophrenia”

How is this done?

Thiothixene is sold in capsules in various strengths or amounts, which are administered according to the severity of the patient’s symptoms.

Taken by mouth, the usual dose of thiothixene is one capsule 1 to 3 times a day. However, the healthcare professional will adjust the dose according to the specific needs of the patient.

Usually, to minimize possible side effects such as sedation or tremor, treatment with thiothixene will begin gradually starting with a small dose and increasing it during the first weeks.

It is very important that the patient follow their doctor’s instructions for writing. Although it may take 2 or 3 weeks before he begins to feel the effects of thiothixene, the patient will never be able to stop taking the medication or take more doses than directed without first consulting a doctor.

If the patient stops taking this drug suddenly, you risk a range of symptoms as a feeling of acute confusion and very severe hallucinations. Therefore, if you need to complete the treatment, it should be carried out gradually and under the supervision of a doctor.

What side effects does it have?

Like many other antipsychotic drugs, thiothixene this includes a number of side effects for the patient this, in some cases, can cause severe irritation to the person.

These side effects can be divided into those that do not require medical attention and those that require medical attention as soon as possible.

In any case, if these side effects increase or prolong over time, it is necessary to inform the doctor about the dose adjustment.

Non-serious side effects

• illness
• vomiting
• constipation
• Weight gain
• Changes in the menstrual cycle
• Descent of desire and sexual behavior

Serious side effects

• dizziness
• fainting
• Feeling embarrassed
• agitation
• fever
• Changes in sweating
• Feeling tired
• Muscle weakness
• Changes in vision
• Breathing problems
• Difficulty speaking and swallowing
• Changes in ability to urinate
• Changes in heart rate
• convulsions
• Muscle stiffness and/or spasms
• Lack of balance
• Difficulty walking
• Breast enlargement in men and women
• Milk production outside lactation

What precautions should be taken when using them?

Before starting treatment, it is essential that the patient informs their physician of any allergy, disease or special health condition they are experiencing that may interfere with the progress of treatment.

There are a number of conditions or diseases that may be aggravated by the use of thiothixene. They are:

• Brain tumors or head injuries
• dementia
• Heart disease
• Blood changes
• Parkinson’s disease
• 9 0005 Kidney changes and liver

In the same way, the doctor should be aware of any drugs, vitamin supplements or natural complexes that the patient consumes both before and during treatment with thiothixene. Since they can cause a series of interference with thiothixene and harm the human body.

Due to its sedative effect, thiothixene may cause drowsiness and dizziness in those who consume it. Therefore, those patients who perform activities such as driving or operating heavy machinery should suspend their activities or at least take special precautions during treatment.

In the same way, consumption of thiothixene during pregnancy and lactation can cause damage to the newborn, so its use should be limited to cases where there is no alternative effective treatment.