What is tyrosine good for. The Comprehensive Guide to Tyrosine: Benefits, Dietary Sources, and Supplements
What is tyrosine good for? Discover the many benefits of this non-essential amino acid, including its role in neurotransmitter production, stress management, and more. Explore dietary sources and proper supplementation.
Understanding Tyrosine: The Versatile Amino Acid
Tyrosine is a non-essential amino acid that plays a crucial role in various bodily functions. The human body can synthesize tyrosine from another amino acid, phenylalanine, making it a non-essential nutrient. Tyrosine is an essential component for the production of important brain chemicals called neurotransmitters, such as epinephrine, norepinephrine, and dopamine. These neurotransmitters are responsible for regulating mood, cognition, and nerve cell communication.
Tyrosine’s Role in Melanin Production and Hormone Function
Beyond its impact on neurotransmitters, tyrosine also contributes to the production of melanin, the pigment responsible for the color of hair and skin. Additionally, tyrosine is involved in the proper functioning of organs that produce and regulate hormones, including the adrenal, thyroid, and pituitary glands.
Potential Benefits of Tyrosine Supplementation
Stress Management
During times of stress, the body may have difficulty producing enough tyrosine from phenylalanine. Some research suggests that tyrosine supplements may help improve memory and performance under psychological stress, potentially by supporting the production of stress-related neurotransmitters.
Sleep Deprivation
One study indicates that taking tyrosine supplements may help individuals maintain alertness and cognitive function after experiencing sleep deprivation. However, more research is needed to confirm these findings.
Thyroid and Lung Health
Preliminary studies suggest that tyrosine kinase inhibitors, a class of compounds that interact with tyrosine, may play a role in the treatment of thyroid cancer and may help improve lung function in individuals with lung cancer or pulmonary fibrosis. Further research is required to substantiate these potential applications.
Dietary Sources of Tyrosine
Tyrosine can be found in a variety of food sources, including soy products, poultry, fish, nuts, seeds, dairy products, and certain fruits and vegetables. Some of the richest dietary sources of tyrosine include:
- Soy products (e.g., tofu, tempeh)
- Chicken and turkey
- Fish
- Peanuts, almonds, and other nuts
- Avocados, bananas, and other fruits
- Dairy products like milk, cheese, and yogurt
- Lima beans, pumpkin seeds, and sesame seeds
Tyrosine Supplements: Considerations and Dosage
Tyrosine is also available in the form of dietary supplements, typically in capsule or tablet form. When taking tyrosine supplements, it’s recommended to consume them at least 30 minutes before meals and divide the daily dosage into three separate servings. Additionally, taking vitamins B6, B9 (folate), and copper along with tyrosine can help the body effectively convert tyrosine into the necessary brain chemicals.
Dosage recommendations for tyrosine supplements can vary, and it’s essential to consult with a healthcare professional or registered dietitian to determine the appropriate dose based on your individual needs and health status.
Addressing Tyrosine Deficiency and Phenylketonuria
Tyrosine deficiency is relatively rare, but it has been associated with low blood pressure, low body temperature, and an underactive thyroid. However, it’s important to note that taking tyrosine supplements may not automatically resolve these conditions.
One serious condition related to tyrosine is phenylketonuria (PKU), a genetic disorder in which the body cannot properly metabolize the amino acid phenylalanine. This can lead to severe neurological complications, including intellectual disability. Individuals with PKU must strictly avoid any sources of phenylalanine, as their bodies cannot convert it to tyrosine. In these cases, tyrosine supplements may be recommended, but only under the guidance of a healthcare professional.
Potential Limitations and Considerations
While tyrosine has shown promise in various applications, it’s important to note that the research on its benefits is still ongoing. Some claims, such as its ability to enhance athletic performance, have not been conclusively proven. Additionally, as with any supplement, it’s crucial to consult with a healthcare provider before incorporating tyrosine into your regimen, particularly if you have any underlying medical conditions or are taking other medications.
In summary, tyrosine is a versatile amino acid that plays a critical role in the production of neurotransmitters, melanin, and various hormones. While tyrosine deficiency is rare, supplementation may offer potential benefits in managing stress, sleep deprivation, and certain health conditions. However, it’s essential to consult with a healthcare professional to determine the appropriate dosage and to ensure the safe and effective use of tyrosine supplements.
Tyrosine Information | Mount Sinai
L-tyrosine
Tyrosine is a nonessential amino acid the body makes from another amino acid called phenylalanine. It is an essential component for the production of several important brain chemicals called neurotransmitters, including epinephrine, norepinephrine, and dopamine. Neurotransmitters help nerve cells communicate and influence mood. Tyrosine also helps produce melanin, the pigment responsible for hair and skin color. It helps in the function of organs responsible for making and regulating hormones, including the adrenal, thyroid, and pituitary glands. It is involved in the structure of almost every protein in the body.
It’s rare to be deficient in tyrosine. Low levels have been associated with low blood pressure, low body temperature, and an underactive thyroid. This does not mean, however, that taking tyrosine supplements will help any of these conditions.
Phenylketonuria (PKU)
This serious condition occurs in people whose bodies can’t use the amino acid phenylalanine. It can lead to brain damage, including intellectual disability. People with PKU must avoid any phenylalanine in their diets. Because tyrosine is made from phenylalanine, people with PKU can be deficient in tyrosine. Tyrosine is used in protein supplements for people with PKU, but most doctors don’t recommend more tyrosine supplements. If you have PKU, your doctor will determine if you need more tyrosine and how much.
Stress
Tyrosine is involved in the production of the stress neurotransmitters epinephrine and norepinephrine. Some researchers believe that, under stress, the body isn’t able to make enough tyrosine from phenylalanine. Some animal and human studies suggest that tyrosine supplements may help improve memory and performance under psychological stress. More research is needed.
Sleep deprivation
One study suggests that taking tyrosine may help you be more alert after sleep deprivation. More research is needed.
Other
Some athletes claim that tyrosine helps their performance. However, there is no proof that this claim is true or safe.
Because tyrosine helps the body produce the mood-influencing chemical dopamine, and because people who are depressed often have low levels of tyrosine, researchers thought that tyrosine might help treat depression. However, studies have found that it has no effect.
Preliminary research suggests that tyrosine kinase inhibitors may play a role in the treatment of thyroid cancer. Other studies suggest tyrosine kinase inhibitors may help improve lung function among people who have lung cancer or pulminary fibrosis. More research is needed.
Dietary Sources
Tyrosine is found in soy products, chicken, turkey, fish, peanuts, almonds, avocados, bananas, milk, cheese, yogurt, cottage cheese, lima beans, pumpkin seeds, and sesame seeds.
Available Forms
Tyrosine is also available as a dietary supplement, in capsule or tablet form.
How to Take It
Take tyrosine supplements at least 30 minutes before meals, divided into 3 daily doses. Taking vitamins B6, B9 (folate), and copper along with tyrosine helps the body convert tyrosine into important brain chemicals.
Pediatric
Don’t give tyrosine supplements to a child without first asking your doctor.
Adult
Doses vary. Talk to your nutritionist or doctor about what dose is right for you. To treat symptoms of sleep deprivation, one study used 150 mg per kilogram of body weight per day.
Precautions
Because of the potential for side effects and interactions with medications, you should take dietary supplements only under the supervision of a knowledgeable health care provider.
People who have migraine headaches should avoid tyrosine, as it can trigger migraine headaches and stomach upset.
People with hyperthyroidism or Graves disease should avoid tyrosine supplements because tyrosine may increase levels of thyroid hormone.
Possible Interactions
If you are being treated with any of the following medications, you should not use tyrosine supplements without first talking to your health care provider.
Monoamine Oxidase Inhibitors (MAOIs) — Tyrosine may cause a severe increase in blood pressure in people taking antidepressant medications known as MAOIs. This rapid increase in blood pressure, also called “hypertensive crisis,” can lead to a heart attack or stroke. People taking MAOIs should avoid foods and supplements containing tyrosine. MAOIs include:
- Isocarboxazid (Marplan)
- Phenelzine (Nardil)
- Tranylcypromine (Parnate)
- Selegiline
Thyroid hormone — Tyrosine is a precursor to thyroid hormone, so it might raise levels too high when taken with synthetic thyroid hormones.
Levodopa (L-dopa) — Tyrosine should not be taken at the same time as levodopa, a medication used to treat Parkinson’s disease. Levodopa may interfere with the absorption of tyrosine.
Supporting Research
Carhill AA, et al. The noninvestigational use of tyrosine kinase inhibitors in thyroid cancer: establishing a standard for patient safety and monitoring. J Clin Endocrinol Metab. 2013;98(1):31-42.
Fernstrom JD. Can nutrient supplements modify brain function? Am J Clin Nutr. 2000;71(6 Suppl):1669S-1675S.
Hoffman JR, Ratamess NA, Gonzalez A, Beller NA, Hoffman MW, Olson M, Purpura M, Jäger R. The effects of acute and prolonged CRAM supplementation on reaction time and subjective measures of focus and alertness in healthy college students. J Int Soc Sports Nutr. 2010 Dec 15;7:39.
Kliegman R, Behrman R, Jenson H, Stanton B. Nelson Textbook of Pediatrics, 19th ed. Philadelphia, PA: Saunders Elsevier; 2011.
Mahoney CR, Castellani J, Kramer FM, Young A, Lieberman HR. Tyrosine supplementation mitigates working memory decrements during cold exposure. Physiol Behav. 2007 May 22; [Epub ahead of print]
Melmed: Williams Textbook of Endocrinology, 12th ed. Philadelphia, PA: Saunders Elsevier; 2011.
Meyers S. Use of neurotransmitter precursors for treatment of depression. Altern Med Rev. 2000;5(1):64-71.
Parry BL. The role of central serotonergic dysfunction in the aetiology of premenstrual dysphoric disorder: therapeutic implications. CNS Drugs. 2001;15(4):277-285.
Poustie VJ, Rutherford P. Tyrosine supplementation for phenylketonuria. Cochrane Database Syst Rev. 2000;(2):CD001507.
Richeldi L, et al. Efficacy of a tyrosine kinase inhibitor in idiopathic pulmonary fibrosis. N Engl J Med. 2011;365(12):1079-87.
Thomas A, Rajan A, giaccone G. Tyrosine Kinase Inhibitors in Lung Cancer. Hematology/Oncology Clinics of North America. 2012;26(3).
Tumilty L, Davison G, Beckmann M, Thatcher R. Oral tyrosine supplementation improves exercise capacity in the heat. Eur J Appl Physiol. 2011 Mar 25. [Epub ahead of print]
van Spronsen FJ, van Rijn M, Bekhof J, Koch R, Smit PG. Phenylketonuria: tyrosine supplementation in phenylalanine-restricted diets. Am J Clin Nutr. 2001;73(2):153-157.
Webster D, Wildgoose J. Tyrosine supplementation for phenylketonuria. Cochrane Database Syst Rev. 2010 Aug 4;(8):CD001507. Review.
Yehuda S. Possible anti-Parkinson properties of N-(alpha-linolenoyl) tyrosine. A new molecule. Pharmacol Biochem Behav. 2002;72(1-2):7-11.
Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews
Overview
Tyrosine is a type of amino acid, which are the building blocks of protein. The body makes tyrosine from another amino acid called phenylalanine.
In the diet, tyrosine can be eaten in dairy products, meats, fish, eggs, nuts, beans, oats, and wheat. The body uses tyrosine to make chemical messengers that are involved in conditions affecting the brain, such as mental alertness.
People most commonly use tyrosine in protein supplements for an inherited disorder called phenylketonuria (PKU). It is also used for alcohol use disorder, cocaine dependence, and memory and thinking skills, but there is no good scientific evidence to support most of these uses.
Uses & Effectiveness ?
Effective for
- An inherited disorder that increases levels of phenylalanine in the blood (phenylketonuria or PKU). People with PKU are not able to process the amino acid phenylalanine. This amino acid is used by the body to make tyrosine. To prevent tyrosine levels from becoming too low, people with PKU are advised to consume medical foods that contain tyrosine and very little phenylalanine.
Possibly Effective for
- Memory and thinking skills (cognitive function). Taking tyrosine by mouth might improve mental performance under stressful conditions.
- Memory. Taking tyrosine by mouth seems to improve memory during stressful situations.
Possibly Ineffective for
- Athletic performance. Taking tyrosine by mouth before running or cycling doesn’t seem to improve performance.
There is interest in using tyrosine for a number of other purposes, but there isn’t enough reliable information to say whether it might be helpful.
Side Effects
When taken by mouth: Tyrosine is commonly consumed in foods. Tyrosine is possibly safe when taken as a medicine, short-term. It seems to be safe when taken in doses up to 150 mg/kg daily for up to 3 months. Some people experience side effects such as nausea, headache, fatigue, and heartburn.
When applied to the skin: Tyrosine is possibly safe when applied to the skin.
Special Precautions and Warnings
Pregnancy and breast-feeding: There isn’t enough reliable information to know if tyrosine is safe to use when pregnant or breast-feeding. Stay on the safe side and stick to food amounts.
Thyroid disorders: The body uses tyrosine to make thyroxine, a thyroid hormone. Taking extra tyrosine might increase thyroxine levels too much. This could make hyperthyroidism and Grave’s disease worse. If you have a thyroid disorder, don’t take tyrosine supplements.
Interactions ?
Tyrosine might decrease how much levodopa the body absorbs. By decreasing how much levodopa the body absorbs, tyrosine might decrease the effects of levodopa. Do not take tyrosine and levodopa at the same time.
The body naturally produces thyroid hormones. Tyrosine might increase how much thyroid hormone the body produces. Taking tyrosine with thyroid hormone pills might cause there to be too much thyroid hormone. This could increase the effects and side effects of thyroid hormones.
Moderate Interaction
Be cautious with this combination
Dosing
In the diet, tyrosine is found in dairy, meats, fish, eggs, nuts, beans, oats, and wheat. In supplements, tyrosine has most often been used by adults in doses of 100-300 mg/kg by mouth daily. Speak with a healthcare provider to find out what dose might be best for a specific condition.
View References
CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.
This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2018.
tyrosine – complete information about the amino acid in the Encyclopedia Evalar
L tyrosine is an optically isomeric form of the aromatic amino acid tyrosine. The substance is involved in lipid metabolism, regulates appetite, improves melanin synthesis, normalizes the functioning of the adrenal glands, pituitary gland, and thyroid gland.
The amino acid L tyrosine is a non-essential amino acid, as it is produced in the body. The disadvantage is partially compensated with protein food. The compound was first discovered in cheese by the German scientist Liebig. Tyrosine is needed to build protein molecules in all tissues, is part of enzymes, and can partially replace molecular crosslinks in case of a lack of other substances in the body.
Synthesis and role in the body
For the formation of tyrosine, phenylalanine is necessary – an essential amino acid, without which synthesis is impossible. Phenylalanine is needed for the structure of protein compounds, and all of its unused residue is converted into tyrosine. Thus, with a deficiency of the precursor substance, a deficiency of tyrosine occurs.
With the participation of L tyrosine, hormones are produced in the adrenal glands and the thyroid gland. During the enzymatic transformation, the skin and hair pigment, melanin, is produced.
The adrenal glands under the action of tyrosine produce hormones of the catecholamine group: adrenaline, norepinephrine, dopamine. These are neurotransmitters that control the functioning of the nervous system, stimulate the brain, improve the passage of nerve impulses. With an increase in physical activity, the production of catecholamines increases, this allows the body to adapt. The faster the endocrine system responds to stress, releasing the necessary substances into the blood, the easier it is for the cardiovascular system and muscles to cope:
Adrenaline – is produced during severe stress or sudden physical impulses. This increases the permeability of cell walls, accelerates the breakdown of fats and carbohydrates for more energy. The body’s endurance during this period increases.
Norepinephrine – secreted during moments of aggression, stress, prolonged hard physical work, injuries. Increases muscle endurance, constricts blood vessels.
Dopamine – improves the absorption of glucose in tissues, stimulates cellular nutrition, constricts blood vessels, causes a feeling of pleasure. Takes part in the formation of growth hormone.
In the thyroid gland, tyrosine is necessary for the synthesis of thyroid hormones – thyroxine and triiodothyronine. These are iodinated amino acids necessary for normal growth and development of tissues, normal mental activity, regulation of metabolism and maintenance of normal body temperature. Substances of this group increase the body’s sensitivity to adrenal hormones.
Effects on body systems
Normalization of the concentration of L tyrosine affects the functioning of all body systems:
Cardiovascular. The compound helps regulate blood pressure, reduces the risk of hypertension, improves vascular tone, nutrition at the cellular level. The frequency and intensity of vegetative-vascular spasms decreases, the heart muscle strengthens.
Nervous. L tyrosine enhances adaptability to psychological and physical stress, stimulates the brain, increases concentration, helps fight depression and the effects of stress.
Endocrine. With the participation of tyrosine, hormones are synthesized in the thyroid gland, adrenal glands, pituitary gland, sex glands in men and women. Their normal work supports cognitive, motor functions, regulates metabolism, helps to form the correct immune response to various types of pathogens.
Metabolism. Under the action of the substance, the breakdown of fats is enhanced and carbohydrate metabolism is normalized. This leads to a decrease in appetite and utilization of lipid deposits.
An excess of tyrosine leads to dramatic weight loss, insomnia, distracted attention, and increased excitability. This condition is associated with an increased concentration of thyroid hormones and requires correction.
The daily minimum requirement for an adult is 60 mg, and at high loads, severe decompensation or in a stressful situation, the consumption can increase to 4 g.
Consequences of deficiency
Insufficient concentration of L tyrosine can lead to a decrease in concentration, loss of endurance, apathy, and with prolonged deficiency, there are:
Puffiness, drowsiness, dry skin, pallor, weight gain. This increases the risk of atherosclerosis, hypertension.
Violation of the liver, kidneys. At the first stage, glucose is no longer absorbed, the cells experience a lack of nutrition, and the work of the excretory system is inhibited.
Food sources
Despite the fact that L-tyrosine is synthesized by our body with the participation of phenylalanine, most often this amount is not enough for the normal operation of all systems. To partially compensate for the deficiency, eating foods such as:
Pork, beef, lamb.
Chicken, turkey, duck.
Fish and seafood.
Cheese, cottage cheese, yogurt, kefir.
Nuts, sunflower seeds, sesame seeds, legumes.
In addition to food sources, you can compensate for the lack of L tyrosine by taking food supplements in the form of capsules, tablets, lozenges.
BAA with tyrosine
These are balanced drugs that are used for conditions such as:
deterioration of cognitive functions, memory, attention;
loss of working capacity, endurance, with constant fatigue;
sudden mood swings, depression, phobias.
In childhood, drugs are prescribed for hyperactivity, increased excitability, difficulty in perceiving new information. L-tyrosine is also indicated for age-related disorders of the brain and nervous system. To enhance the effect in additives, in addition to tyrosine, phenylalanine is present.
The method of application for each additive is indicated in the instructions. In most cases, dietary supplements are drunk in the morning, an hour before meals. Wash down with water or juice at room temperature. The average course duration is 30-45 days.
Side effects and contraindications
Dosages and duration of administration are selected by specialists. The drugs did not reveal any side effects while following the selected scheme.
Possible contraindications:
Pregnancy and breastfeeding.
Hyperthyroidism.
Hypertension.
Taking antidepressants based on monoamine oxidase inhibitors.
Allergic reactions to the components of the drug.
Schizophrenia.
If the start of supplementation with L tyrosine coincided with the appearance of other symptoms, it is recommended to stop taking it and seek the advice of a doctor.
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✒ Tyrosine – Benefits, Side Effects & Dosage – [SAYYES]
Tyrosine is a popular dietary supplement used to improve alertness and concentration. This substance is used in the human brain to carry out a number of important chemical processes, transmit nerve impulses, and regulate mood.
Although tyrosine has several benefits, some medications may cause side effects when used with tyrosine. In order to avoid misuse of this supplement, below we will review its basic information, recommendations for use, and potential risks associated with its abuse.
What is tyrosine and what is it for? The first compound is found in common products available to everyone. However, its greatest amount is observed in cheese, where tyrosine was discovered for the first time. This substance is also found in chicken, fish, milk, and high-protein foods.
According to research data, tyrosine is involved in the synthesis of a number of important substances for the human body, such as:
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If your diet is deficient in high tyrosine foods, doctors recommend the use of appropriate nutritional supplements. Adding them to the diet can increase the amount of dopamine, adrenaline and norepinephrine, which will lead to improved memory and improve reaction in stressful situations and brain function.
Effect of tyrosine on stress levels
nii and transmission of nerve impulses. So, for example, in rodents whose body was constantly exposed to low temperatures, scientists noted a decrease in the level of neurotransmitters, which caused memory impairment. However, the use of tyrosine supplements made it possible to reverse the process and normalize brain function in animals. Although laboratory studies on rats cannot be used to confirm the effect of a substance on the human body, experiments involving humans have shown a similar result.
One study of 22 women found that adding tyrosine to the diet increased the speed of problem solving. Scientists attribute this effect to an increase in concentration levels.
Another experiment looking at the compound’s effect on cognitive flexibility found that tyrosine improved the ability to quickly switch from one task to another while maintaining performance levels. In addition, regular intake of tyrosine has been found to improve brain function in sleep-deprived people and keep their concentration levels up to 3 hours longer than placebo.
An analysis of a number of studies has shown that the addition of this compound to the diet can reverse the process of mental decline. Also, the supplement can improve the cognitive abilities of the brain in stressful and psychologically difficult situations. And despite some evidence that tyrosine can improve brain function, there is not a single study that confirms the ability of this compound to increase the level of physical performance.
The scientists also report that none of the previous studies have shown that tyrosine is able to improve brain function outside of stressful situations. In other words, the inclusion of this supplement in the diet will not improve mental abilities.
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Tyrosine can be used to treat phenylketonuria
Phenylketonuria (PKU) is a genetic disease that interferes with the synthesis of phenylalanine hydroxylase. This enzyme is used by the human body to generate neurotransmitters and also to break down phenylalanine.
The main treatment for this genetic disorder is a specialized diet that includes foods high in phenylalanine. But due to the fact that tyrosine is synthesized from this substance, individuals suffering from PKU may experience an acute deficiency of it. Based on this, the scientists concluded that tyrosine supplements can improve the condition of people with phenylketonuria.
Analysis of research data showed that the regular use of dietary supplements of tyrosine in combination with a specialized diet for patients with PKU positively affects the growth of intelligence, improves quality of life and reduces the risk of death. However, some studies have shown that there is practically no difference between the use of supplements and placebo. Therefore, it is impossible to draw unambiguous conclusions about the need for the use of tyrosine in the treatment of PKU.
Should l tyrosine be used for depression
zine can help people who are depressed. This condition is associated with an imbalance of neurotransmitters in the human brain. For its treatment, as a rule, antidepressants are prescribed, which contribute to the production of additional neurotransmitters. But because tyrosine has the same property, it can be used as an alternative to antidepressants.
Despite this, some previous studies refute this claim. So, in one of the experiments, one group with depression was given 100 milligrams of tyrosine per 1 kilogram of its own weight in combination with antidepressants, and the other amino acid was replaced with a placebo. After the study was completed, it was found that tyrosine has no effect on depression.
According to doctors, depression is a rather complex condition that varies from person to person. Therefore, the use of tyrosine in its treatment can help only a few. Despite this, the inclusion of an appropriate supplement in the diet increases the level of adrenaline, dopamine and norepinephrine, which will provide benefits to the body.
One study in people whose depression was caused by low levels of dopamine showed that tyrosine could improve their condition. The participants in the experiment experienced an increase in the amount of energy and an increase in motivation.
The results of studies on the effect of tyrosine on depression are inconsistent. Therefore, further experiments will be required to determine the usefulness of the substance in this area.
Side effects of l-tyrosine
Doctors report that tyrosine is an absolutely safe dietary supplement, provided it is used in the recommended amounts, that is, up to 150 milligrams per 1 kilogram of body weight. Despite this, in combination with certain drugs, this compound may cause unwanted side effects.
Monoamine oxidase inhibitors (MAOIs)
Tyramine is an amino acid that helps normalize blood pressure levels. It is formed during the breakdown of tyrosine in the human body, and can also be ingested from certain foods, such as:
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MAOIs, also commonly referred to as antidepressants, block an enzyme called monoamine oxidase, which helps break down excess tyramine. This, in turn, can cause an increase in blood pressure to a critical state.
But it remains unknown whether tyrosine can cause tyramine accumulation. Therefore, doctors strongly do not recommend using this supplement in combination with antidepressants.
Thyroid hormones
Substances such as thyroxine and triiodothyronine are the main thyroid hormones. They are responsible for metabolism and cell growth. Therefore, it is very important that the indicators of these hormones do not exceed the permissible value and are not below it.
Adding l-tyrosine to the diet may lead to an increase in thyroxine and triiodothyronine. This is due to the fact that this amino acid acts as a building material for the creation of thyroid hormones. For the same reason, individuals taking thyroid medication should be extremely careful when including tyrosine in their diet.
Levodopa
A drug called Levodopa is often prescribed to treat Parkinson’s disease. Its active components compete with tyrosine for absorption by the body in the small intestine, which can adversely affect the effectiveness of the drug. Therefore, doctors recommend taking tyrosine supplements 2 hours before or after taking the drug. At the same time, the researchers note that tyrosine is able to eliminate some of the symptoms of diseases associated with impaired cognitive functions.
Recommendations for the use of tyrosine
form of the amino acid N-acetyl-L-tyrosine (NALT). This form of the substance is highly soluble in water, but is slowly absorbed. This means that the volumes of NALT used to meet the needs of the body must be higher than pure tyrosine.
In order to increase the effectiveness of training, the last form of the substance is recommended to be included in the diet in the amount of 500 to 2000 milligrams 30-60 minutes before the start of physical activity. To improve brain function, tyrosine should be taken in a ratio of 100 to 150 milligrams per 1 kilogram of its own weight.
Use of higher amounts of supplements may lead to gastrointestinal disturbances. Therefore, the recommended volume should be divided into two doses. Tyrosine is a fairly popular dietary supplement that is used for a variety of purposes. It can be used to increase the amount of neurotransmitters that improve brain function in stressful situations, as well as to increase the effectiveness of certain drugs.
According to scientists, this supplement is absolutely safe. However, it may interact with some medications. Therefore, before including it in the diet, it is important to consult with your doctor.
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SOURCES
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