What are the uses of miconazole nitrate vaginal? What are the side effects of miconazole nitrate vaginal? What are the interactions of miconazole nitrate vaginal? What do pictures of miconazole nitrate vaginal look like? What are the warnings about miconazole nitrate vaginal? How should miconazole nitrate vaginal be dosed?

Understanding Over-the-Counter Yeast Infection Treatments

Three out of four people with vaginas will experience yeast infections at some point in their lifetime. These occur when an overgrowth of the organism Candida penetrates the superficial layers of the skin, leading to symptoms like itching, burning, and redness. To address this common issue, there are many over-the-counter (OTC) yeast infection medications available.

Active Ingredients in Yeast Infection Treatments

Effective treatment for a yeast infection typically involves an antifungal medication, often ending in “-azole” such as fluconazole (for oral treatments) or miconazole (for topical treatments). Prescription topical medications may also contain steroids to help ease inflammation and related discomfort. Some OTC treatments focus more on symptom relief, containing ingredients like benzocaine (a numbing agent), resorcinol, and hydrocortisone (a mild steroid).

Dosage and Usage of Yeast Infection Medications

Dosage instructions are usually clearly printed on product packaging. The vaginal treatment can be for one, three, or seven days depending on the severity of symptoms. Oral treatments are generally better tolerated and more cost-effective than OTC options. However, if you don’t see relief within one to three days, it’s important to contact a doctor, as the underlying issue may require a different treatment approach.

Choosing the Right Yeast Infection Treatment

When selecting an OTC yeast infection medication, consider the form that will be most comfortable and effective for you. Options include inserts, creams, and oral pills. If you’ve never used these types of products before, an insert may seem intimidating, while a cream may provide more immediate soothing relief. Ultimately, the best choice will depend on your personal preferences and the severity of your symptoms.

Potential Issues with OTC Yeast Infection Treatments

It’s important to note that OTC therapies may not work if the yeast infection is caused by a resistant strain of Candida or if the diagnosis is incorrect. In these cases, a doctor may need to prescribe an alternative medication or therapy. Additionally, if symptoms do not improve within one to three days, it’s crucial to seek medical attention to ensure proper treatment.

Miconazole Nitrate Vaginal: Key Information

Miconazole nitrate vaginal is a common antifungal medication used to treat yeast infections. What are the key details about this OTC treatment?

Uses of Miconazole Nitrate Vaginal

Miconazole nitrate vaginal is used to treat vaginal yeast infections caused by the fungus Candida. It works by stopping the growth of Candida, which allows the infection to clear.

Side Effects of Miconazole Nitrate Vaginal

Common side effects of miconazole nitrate vaginal include vaginal burning, itching, irritation, and redness. More serious side effects, though rare, may include allergic reactions, hives, difficulty breathing, and swelling of the face, lips, tongue, or throat.

Interactions of Miconazole Nitrate Vaginal

Miconazole nitrate vaginal may interact with certain medications, such as warfarin (a blood thinner) and prescription antifungal medications. It’s important to inform your healthcare provider of all medications you are taking before using miconazole nitrate vaginal.

Pictures of Miconazole Nitrate Vaginal

Miconazole nitrate vaginal is typically available in the form of a vaginal cream or suppository. The cream is a white, smooth ointment, while the suppository is a small, solid insert designed for vaginal application.

Warnings About Miconazole Nitrate Vaginal

Miconazole nitrate vaginal should not be used if you have a history of allergy to miconazole or other azole antifungal medications. It’s also important to avoid sexual intercourse during treatment and for several days afterward, as this can affect the medication’s effectiveness.

Dosing Instructions for Miconazole Nitrate Vaginal

The recommended dosage of miconazole nitrate vaginal is one full applicator of cream or one suppository inserted into the vagina, typically once daily for 7 days. It’s important to follow the dosage instructions carefully and complete the full course of treatment, even if symptoms improve before the end of the treatment period.

Over The Counter Yeast Infection Treatment

Here’s where yeast infection medications can get confusing. There are so many different options of yeast infection treatments, including inserts, creams, and oral pills. If you’ve never had a yeast infection before or don’t have any experience taking these medications, something like an insert may be intimidating. If you’re experiencing extreme itch or burning, a cream might sound immediately soothing.

6 Best Over-the-Counter Yeast Infection Medicines of 2023

Jennifer Nied has written about health, fitness and wellness for over 10 years. She has a degree in magazine journalism from Northwestern University’s Medill School of Journalism.

Brittany Leitner is a freelance writer and poet. She has a degree in journalism from Syracuse Univeristy and her book, “23 Emotions” is currently on sale online and in NYC bookstores.

Updated on March 18, 2022

Chris Vincent, MD, is board-certified in family medicine. He is a clinical professor at the University of Washington School of Medicine and practices at Harborview Medical Center in Seattle.

Marley Hall is a writer and fact checker who is certified in clinical and translational research. Her work has been published in medical journals in the field of surgery, and she has received numerous awards for publication in education.

Three out of four people with vaginas will experience yeast infections at some point in their lifetime. “People become symptomatic when an overgrowth of the organism, typically Candida, penetrates the superficial layers of the skin,” says Barbara Frank, MD, an OB-GYN in Brookline, Massachusetts, and medical adviser to Attn: Grace. Because yeast infections can cause itching burning, and redness, it’s important to have over-the-counter yeast infection medicines on hand.

Reviewed & Approved

Monistat’s 1-Day Yeast Infection Treatment is formulated with 6.5% tioconazole ointment to treat yeast. Vagisil’s Anti-Itch Creme has anti-itch ingredients and provides quick relief.

Yeast infection medications include antifungal cream. However, if the infection spreads to a larger area or you’re one of the few people who experiences them frequently, a doctor’s visit and oral prescription medication may be necessary.

We researched dozens of over-the-counter yeast infection medicines and evaluated them for price, ingredients, uses, and symptoms targeted. Each of the over-the-counter yeast infection medicines chosen in this article was determined to be the best of these factors.

What to Look for in Yeast Infection Treatments

Dosage

Dosage instructions are usually printed clearly on product boxes or packaging. However, Dr. Frank notes that you can use dosages depending on the severity of your symptoms. “The vaginal treatment can be for one, three, or seven days depending on the severity of your symptoms,” says Dr. Frank. “Most people tolerate the oral treatment much better, and it has the added benefit of being much cheaper than over-the-counter. ”

However, Felice Gersh, MD, OB-GYN, founder of the Integrative Medical Group of Irvine, in California, and author of PCOS SOS Fertility Fast Track, notes that if you don’t see immediate relief (within one to three days), you should contact a doctor immediately. “Naturally, OTC therapies will not work when the diagnosis is incorrect. Also, OTC therapies will not work well if the yeast is a resistant strain to the medication. When that happens, it’s time to switch to an alternative therapy—whether from the OTC to the oral medication, or the other way,” she says.

Active Ingredients

There are a variety of active ingredients found ineffective yeast infection treatments. “Effective treatment for a yeast infection is typically a type of antifungal,” says Dr. Frank. “Those usually end in -azole, such as fluconazole (for oral treatments) or miconazole (for topical treatments).” She adds that prescription topical medications may also have steroids to help ease inflammation and related discomfort.

Dr. Gersh notes, “Medications that only address the symptoms of burning and itching include the ingredients benzocaine (a numbing agent), resorcinol, and sometimes hydrocortisone (a mild steroid).” She adds, “There is an OTC local anesthetic cream containing benzocaine 5% and resorcinol 2%,” so if you’re looking for something to numb symptoms fast, look for a combination of those two ingredients.

Additionally, “mineral oil is an ingredient that may help as a soothing ingredient,” notes Dr. Gersh. Benzocaine, resorcinol, and hydrocortisone are ingredients that soothe the symptoms.

Form

Here’s where yeast infection medications can get confusing. There are so many different options of yeast infection treatments, including inserts, creams, and oral pills. If you’ve never had a yeast infection before or don’t have any experience taking these medications, something like an insert may be intimidating. If you’re experiencing extreme itch or burning, a cream might sound immediately soothing.

“The most popular varied treatments include vaginal creams and suppositories and oral tablets,” says Dr. Gersh. “Comparing the vaginal therapies to the oral ones, both work fairly well. Unfortunately, there are now resistant strains of yeast that no longer respond well to either therapy.”

Though uncommon, it is possible for men to get yeast infections as well. Dr. Frank says that this can happen “in the glans of the penis (more likely if uncircumcised) or in the groin folds, but it is much less common.” If this is the case, there are certain products for men to manage yeast infection symptoms. Look for products that advertise as relieving “jock itch,” or burning, itching, chafing, etc.

Frequently Asked Questions

Does yeast infection medication delay your period?

Not inherently, but if you get stressed out about it, the stress can delay your period, according to Sophia Yen, MD, MPH, the co-founder and CEO of Pandia Health.

Can you take yeast infection medication if you’re not sure you have a yeast infection?

“I do not recommend it. Your vagina has natural yeast and bacteria that coexist in harmony. You should only use yeast infection medication when the yeast gets out of control. If you use it when the yeast is in harmony, the medication will kill the yeast, and the bacteria may take over, causing bacterial vaginosis,” says Dr. Yen.

Can you drink alcohol while taking yeast infection medication?

You can drink alcohol while using yeast infection medication vaginally. However, if you are using the prescription oral medication for yeast infection (metronidazole), you should not drink alcohol with it. If you do, you risk a disulfiram reaction (nausea, vomiting, etc.), according to Dr. Yen.

Below, you’ll find the best over-the-counter yeast infection medicines on the market today.

6 of the best yeast infection treatments to consider in 2023

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Medical News Today only shows you brands and products that we stand behind.

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Yeast infections treatments may include over-the-counter (OTC) or prescription pills or topical medications. This article explains the different options people have to treat a vaginal yeast infection at home following diagnosis.

A quick look at 6 of the best yeast infection treatments

• Best range of treatments:Monistat
• Best pill:Fluconazole
• Best rapid treatment:FemiClear Yeast Infection 2-Day Treatment
• Best preventive treatment:Uqora Promote
• Best preventive suppository:Love Wellness The Killer
• Best budget treatment:CVS Health Miconazole 7-Day Vaginal Treatment

A note about sex and gender

Sex and gender exist on spectrums. This article will use the terms “male,” “female,” or both to refer to sex assigned at birth. Click here to learn more.

Yeast infections occur due to an overgrowth of Candida. This is a type of fungus that normally lives in areas of the body such as the vagina and mouth.

According to the Office on Women’s Health (OWH) , most females will experience a vaginal yeast infection at some point in their life.

The Centers for Disease Control and Prevention (CDC) explain that some common symptoms of a vaginal yeast infection include:

• pain during sexual intercourse
• itchiness or soreness around the vagina
• unusual discharge from the vagina
• discomfort or pain during urination

They add that risk factors for developing an overgrowth of Candida include:

• using hormonal birth control
• being pregnant
• recent antibiotic use
• having a weakened immune system
• having diabetes

The OWH points out that a yeast infection may develop due to sexual intercourse. However, doctors do not classify this as a sexually transmitted infection (STI).

Since yeast infection symptoms are similar to those of other infections and conditions, such as contact dermatitis, a person should contact a doctor before taking any OTC medications. The doctor can test for yeast or other infections to provide the appropriate treatment.

Doctors typically recommend OTC antifungal medications to treat a vaginal yeast infection.

Antifungal medications come in a variety of forms, including:

• creams
• tablets
• ointments
• vaginal suppositories

Treatments may come as one single dose or a daily dose over several days. A person should read the dosing instructions carefully to ensure they use the correct dosage.

Some of the products in this article are classed as homeopathic treatments.

There are no FDA-approved homeopathic products. This means that any product sold in the U.S. and marketed as homeopathic is not FDA approved and the FDA has not tested it for safety or effectiveness.

MNT chose yeast infection treatments that meet the following criteria:

• Reputable brands: Our medical and business teams have thoroughly researched all brands in this article to ensure their safety and reputability. This means the brands we chose do not make unsupported health claims and their products do not contain unsafe ingredients.
• Accessibility:MNT chose brands that are widely available in-store, online, and over the counter.
• Cost:MNT selected nonprescription items with some of the most budget-friendly price points. For prescription products, MNT ensured multiple payment options, including health savings accounts (HSAs) and flexible savings accounts (FSAs).
• Treatment times:MNT chose products that claim to treat yeast infection symptoms in as few days as possible.
• Treatment type:MNT chose products that have a range of treatment types, such as pills, probiotics, and suppositories.

Please note that the writer of this article has not tried these products. All information presented is purely research-based and correct at the time of publication.

Medical News Today follows a strict product selection and vetting process. Learn more here.

Best range of treatments: Monistat

• List price: around $14 for a pack of three applicators
• Active ingredients: miconazole nitrate
• Treatment time: 1, 3, or 7 days
• Supply: 1, 3, or 7 prefilled applicators

Monistat is available in several pharmacies and retail stores, including Walmart, throughout the United States. It provides treatment options that include 1, 3, and 7 days’ worth of doses.

This product comes in the form of internal suppositories and external creams with applicators that help people place the yeast infection treatment in the right area. Some packs include additional topical itch medications to help ease symptoms.

Each applicator contains 200 milligrams (mg) of miconazole nitrate, a medication that treats fungal infections.

This product is most suited to individuals who currently have a yeast infection and would like to try multiple methods to treat it.

Pros

• readily available in retail stores
• various treatment options available in one pack
• FSA- and HSA-eligible
• affordable price

Cons

• reviews mention burning, stinging, or itching sensations
• may cause heavy discharge

Best pill: Fluconazole

• List price: $15 quarterly fee or a $65 one-time fee
• Active ingredients: generic fluconazole
• Treatment time: 2 days
• Supply: up to 2 pills

Fluconazole is a generic version of the prescription pill Diflucan, which people can take to treat yeast infections.

Individuals need to take a single pill first. If symptoms do not improve after 2 days, they can take a second pill.

Online pharmacies, such as Wisp, offer quick delivery of fluconazole. They can also provide same-day or rushed prescriptions to a person’s local pharmacy.

Wisp offers subscriptions for those who regularly have yeast infections and accepts FSA and HSA cards as payment.

This product may be most suitable for individuals who regularly experience yeast infections or when creams have not worked.

Pros

• available for same-day pick up from a local pharmacy
• FSA- and HSA-eligible
• subscription service available

Cons

• one-time purchases are expensive
• Wisp does not accept insurance

Best rapid treatment: FemiClear Yeast Infection 2-Day Treatment

• List price: around $20
• Active ingredients: olive oil, melaleuca, calendula, and lavender essential oil
• Treatment time: 2 days
• Supply: two suppositories

FemiClear’s 2-day yeast infection treatment includes two suppositories that a person inserts into their vagina and an external anti-itch ointment for symptom relief.

The product contains calendula, tea tree oil, olive extract, beeswax, and olive oil to combat itching and discomfort.

The company recommends using this yeast infection treatment before bed or wearing a panty liner to ensure that it does not leak.

Older 2015 research found that tea tree oil may help improve difficult-to-treat yeast infections when combined with other treatments, such as fluconazole.

However, research is limited, and another 2015 study found that tea tree oil may only improve yeast infections caused by certain types of Candida bacteria.

The FDA classes this product as an unapproved homeopathic treatment and states it has not tested it for safety or efficacy. The FDA writes that it is not aware of scientific research that supports the effectiveness of homeopathic remedies.

This may best suit individuals who currently have a yeast infection and prefer to use organic ingredients. However, it is unsuitable for vegans because it contains beeswax.

Pros

• organic ingredients
• affordable price
• treatment lasts 2 days

Cons

• unsuitable for vegans
• does not have FDA approval
• suppository may not suit some people

How to Use MONISTAT® Yeast Infection Treatment

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Not Sure How To Treat?

How do you treat a yeast infection without a prescription? It’s easy! You reach for the #1 gynecologist recommended OTC brand, MONISTAT®. MONISTAT® offers 1-day, 3-day and 7-day yeast infection treatments— which come in a variety of formats, and some which come with external itch cream, called a “Combination Pack.” The number of “days” of treatment corresponds to the number of doses– so a “3-Day” treatment means you’ll use 3 doses to treat your yeast infection. Although the number of “days” of treatment varies with the 1-day, 3-day and 7-day products, all doses cure most vaginal yeast infections in the same amount of time, equally and effectively.

An important note, before we explain the directions for how to use MONISTAT® treatments: While our products can be used by adults and children over 12, do not self-treat with MONISTAT® if this is your first yeast infection.

If a doctor has told you in the past that you had a vaginal yeast infection and you have the same symptoms now (such as vaginal discharge, itching or burning), then MONISTAT® products may work for you.

If you have another medical condition, like diabetes, or are pregnant, please talk to your doctor before buying and using MONISTAT®.

You can use these treatments while you have your period. However, do not have sex or use tampons, douches, spermicides, condoms or diaphragms until after you have completed the treatment and your symptoms are gone.

Below you will find instructions on how to apply each MONISTAT® yeast infection product.  However, once you buy Monistat®, you should read the entire leaflet that comes in the box.

MONISTAT® 1 products are maximum strength, single-dose yeast infection treatments designed to be an easy solution for busy women with active lifestyles. The one-day ovule has been formulated so you can apply the treatment during the day or at night, whereas all other Monistat® treatments should be used at night Below you’ll find MONISTAT® 1-Day directions for use for both MONISTAT® 1 products.

• How to use MONISTAT® 1-Day Treatment Combination Pack Ovule (miconazole nitrate)

  The Monistat 1-Day Treatment Combination Pack includes a  single Ovule insert that goes directly in the vagina with an applicator and a cream to relieve external itching and irritation. It’s important to keep the Ovule insert dry before use.

  How to insert the ovule: When ready, open the pouch and put the Ovule in at the top (wider) end of the applicator. (See the illustration in the instructions.) Once the Ovule is secure in the applicator, hold the applicator at the bottom end and insert the top end into your vagina as far as it will comfortably go, like you would a tampon. Push in the moveable plunger with your finger so the Ovule gets inserted in your vagina. Gently pull out the empty applicator and throw it away (do not flush). The ovule gradually melts to deliver medicine directly to the site of the infection.

  The MONISTAT® 1 Ovule® stays in place and can be used day or night, making it a great solution for women who don’t want to wait until bedtime to begin treating their yeast infection, or for those who exercise frequently or engage in high levels of activity.

  How to apply the external itch cream: To relieve external itching and irritation, you can use the included itch cream on the skin outside your vagina for up to 7 days. Apply the cream once in the morning and once before bedtime, as needed.

  You can find and download full instructions here..

• How to use MONISTAT® 1-Day Treatment Prefilled Ointment (tioconazole)

  This MONISTAT® 1-Day treatment uses a different ingredient than the combination pack above. Because some women may be sensitive to the high dose of miconazole nitrate used in the other Monistat 1-Day treatment, this prefilled ointment uses tioconazole 6.5%.

  This vaginal antifungal product includes one dose of ointment in a ready-to-use, convenient, pre-filled applicator. First remove the pre-filled applicator from its wrapper. Unscrew and remove the purple cap from the applicator. Then insert the plunger into the prefilled applicator by placing the small end of the plunger into the gray hole at the end of the applicator (see illustration on instructions). Gently insert the applicator into the vagina as far as it will go comfortably. This can be done while lying on your back or standing. As you would with a tampon, use a finger on the other hand to push the plunger in all the way. This action will place the ointment as far back in the vagina as possible. Then remove both parts of the applicator from the vagina and throw away—do not flush. You should use this product right before bedtime and wear a pad or pantiliner.

  You can find and download full instructions here.

MONISTAT® 3 products spread out the dosage of yeast infection treatment over three days. This selection is a great option for women who want consistent treatment and relief at moderate dosage levels, instead of a one-day higher dose. Below you’ll find directions for using four different MONISTAT® 3-Day products.

• How to use MONISTAT® 3-Day Treatment Combination Pack Suppositories (miconazole nitrate)

  This pack comes with 3 vaginal suppository inserts and disposable applicators. It also includes itch cream for external itch relief. You should use this product right before bedtime and wear a pad or pantiliner.

  How to insert the suppositories: Take one suppository out of the packaging and put it in the top of the applicator so it won’t fall out. Hold the applicator from the bottom end where the moveable plunger is, and insert the applicator into your vagina as far as it will comfortably go. Push the plunger in to release the suppository, as you would normally insert a tampon. Pull out both parts of the applicator and throw it away (do not flush). Wash your hands, then lie down as soon as possible to minimize any leakage. Repeat these steps over the next 2 nights with the remaining suppositories.

  How to apply the external itch cream: To relieve itching and irritation, you can use the included external itch cream on the skin outside your vagina for up to 7 days. Apply the cream once in the morning and once before bedtime, as needed.  

  Download full instructions here.

• How to use MONISTAT® 3-Day Treatment Combination Pack Ovule® (miconazole nitrate)

  This regular strength yeast infection treatment comes with 3 Ovule® inserts and contoured disposable applicators for easy use. Plus it includes a cream for external itch relief.

  How to insert the ovule: When ready, open the pouch and put the Ovule in the top (wider) end of the applicator. (See the illustration in the instructions.) Once the Ovule is securely placed, hold the applicator at the bottom end and insert the top end first into your vagina as far as it will comfortably go, like you would a tampon. Push in the moveable plunger using a finger on your other hand to place the Ovule in your vagina. Gently pull out the empty applicator and throw away (do not flush).  You should use this product right before bedtime and wear a pad or pantiliner. Repeat these steps over the next 2 nights.

  How to apply the external itch cream: To relieve itching and irritation, you can use the included external itch cream on the skin outside your vagina for up to 7 days. Apply the cream once in the morning and once before bedtime, as needed.  

  You can find and download full instructions here.

• How to use MONISTAT® 3-Day Treatment Combination Pack Prefilled Cream (miconazole nitrate)

  This MONISTAT® combination pack contains a regular strength yeast infection treatment that comes in 3 prefilled, ready-to-use applicators. It also includes itch cream for external itch relief.

  How to insert the cream: First remove the pre-filled applicator from its wrapper. Unscrew and remove the blue cap from the applicator. Then insert the plunger into the prefilled applicator by placing the small end of the plunger into the gray hole at the end of the applicator (see illustration on instructions). Gently insert the applicator into the vagina as far as it will go comfortably. This can be done while lying on your back or standing. As you would with a tampon, use one hand holding the applicator in place, and use a finger to push the plunger in all the way. This action will place the cream as far back in the vagina as possible. Then remove both parts of the applicator from the vagina and throw away—do not flush. Repeat these steps using the other pre-filled applicators over the next 2 nights.

  You should use this product right before bedtime and wear a pad or pantiliner.

  How to apply the external itch cream: To relieve itching and irritation, you can use the included external itch cream on the skin outside your vagina for up to 7 days. Apply the cream once in the morning and once before bedtime, as needed.  

  You can find and download full instructions here.

• How to use MONISTAT® 3-Day Treatment Prefilled Cream (miconazole nitrate)

  MONISTAT® 3-Day Treatment Prefilled Cream is a regular strength yeast infection treatment that comes with 3 prefilled, ready-to-use applicators. For the best experience, you should use this product right before bedtime and wear a pad or pantiliner.

  First remove the pre-filled applicator from its wrapper. Then remove the blue cap from the applicator, and insert the plunger into the prefilled applicator. Do this by placing the small end of the plunger into the gray hole at the end of the applicator (see illustration on instructions). Gently insert the applicator into the vagina as far as it will go comfortably, as if you are inserting a tampon. This can be done while lying on your back or standing. Use one hand to hold the applicator in place, and use a finger o to push the plunger in all the way. This action will place the cream as far back in the vagina as possible. Then remove both parts of the applicator from the vagina and throw away—do not flush.

  Lie down as soon as possible after inserting the cream to help reduce leakage. Repeat these steps using the other pre-filled applicators over the next 2 nights.

  You can find and download full instructions here.

Some women want to use a yeast infection treatment that uses a lower dose over a longer time period. For example, the U.S. CDC recommends that women who are pregnant or have diabetes only use a 7-day topical yeast infection treatment instead of higher dose and internal options.  (Note, women who are pregnant or diabetic should consult their healthcare provide before using Monistat or any other treatment.)

MONISTAT® 7 is a low dose yeast infection treatment. Learn how to use both of our MONISTAT® 7 treatments, below.

• How to use MONISTAT® 7-Day Treatment Combination Pack Cream (miconazole nitrate)

  MONISTAT® 7-Day Treatment Combination Pack Cream is a low dose yeast infection treatment that comes with 7 empty applicators and a tube of cream that you put into each applicator before using. This pack also includes itch cream for external itch relief.

  How to insert the cream: Open the tube of miconazole nitrate vaginal cream and press the sharp point of the cap into the sealed end of the tube until the seal breaks open. Attach the applicator to the tube of cream by placing the “A” end of the applicator firmly onto the tube of cream (see picture in instructions). Do not pull out the applicator plunger. Gently squeeze the cream into the applicator until the applicator is full, which you’ll see when the plunger has been fully pushed out.  Once it is full, separate the applicator from the tube. Do not release pressure on the tube until you have separated it from the filled applicator. Replace the cap and roll up the empty part of the tube from the bottom. Similar to how you would use a tampon, gently insert the applicator into your vagina as far as it will go comfortably. To do this, you can lie on your back with your knees bent or standing. With one hand holding the applicator barrel, use a finger on your other hand to push the plunger all the way in. This will place the cream as far back in the vagina as possible. Then remove both parts of the applicator from the vagina. Throw away the applicator after use. Do not flush any part of it in the toilet.

  Wash your hands and then lie down as soon as possible after inserting the cream. This will help reduce leakage. Over the next 6 days, repeat these steps. You should use this product right before bedtime and wear a pad or pantiliner.

  How to apply the external itch cream: To relieve itching and irritation, you can use the included external itch cream on the skin outside your vagina for up to 7 days. Apply the cream once in the morning and once before bedtime, as needed.

  You can find and download full instructions here.

• How to use MONISTAT® 7-Day Treatment Cream (miconazole nitrate)

  MONISTAT® 7-Day Treatment Cream is a low dose yeast infection treatment that comes with a tube of treatment cream and 7 empty applicators. You fill each one right before you use it. This cream can be used inside the vagina or on the skin outside of the vagina, around the vulva to relieve itching.

  How to insert the cream:  Open the tube by unscrewing the cap. Press the sharp point of the cap into the sealed end of the tube to break open the seal. Attach the applicator to the tube of cream by placing “A” end of the applicator firmly onto tube of cream (see illustration in instructions). Do not pull out the applicator plunger. Gently squeeze the cream into the applicator until the applicator is full, which you’ll see when the plunger has been fully pushed out. Separate the applicator from the tube. Do not release pressure on the tube until you have separated it from the filled applicator. After each use, replace the cap and roll up the tube over the empty part from the bottom.

  Gently insert the applicator into the vagina as far as it will go comfortably, like you would with a tampon. You can do this while lying on your back with your knees bent standing. With one hand holding the applicator barrel, use the other hand to push the plunger all the way in. This will place the cream as far back in the vagina as possible. Then remove both parts of the applicator from the vagina and throw them away—do not flush them in a toilet.

  Lie down as soon as possible after inserting the cream to help minimize leakage. Repeat these steps each night before bedtime for the next 6 days.

  You can find and download full instructions here.

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This document, provided by Lexicomp ^® , contains all the information you need to know about this medicine, including indications, directions for use, side effects, and when your healthcare provider should be contacted.

Trade names: USA

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Warning

• Do not use this drug if you are pregnant. It can be harmful to the fetus. Before you start taking this drug, you will have a pregnancy test to confirm that you are NOT pregnant. If you are taking this medication on a monthly basis, you will also need to take a pregnancy test before each monthly dose to prevent a yeast infection from recurring.
• If you can become pregnant, you must use birth control during treatment and for 4 days after your last dose of this drug. If you become pregnant, contact your doctor immediately.

What is this drug used for?

• This drug is used to treat vaginal fungal infections.
• It is used to reduce the risk of vaginal yeast infections, which may come back in some people.

What should I tell my doctor BEFORE taking this drug?

For all patients taking this drug:

• If you have an allergy to this drug, any of its ingredients, other drugs, foods or substances. Tell your doctor about your allergies and how they have manifested.
• If you are taking any of the following drugs: Barbiturates such as phenobarbital, bosentan, carbamazepine, efavirenz, etravirine, phenytoin, rifampin, or St. John’s wort.

Children:

• If your daughter has not started her period.

This list of drugs and conditions that may interact with this drug is not exhaustive.

Tell your doctor and pharmacist about all medicines you take (prescription and over-the-counter, natural products and vitamins) and any health problems you have. You need to make sure that this drug is safe for your conditions and in combination with other drugs you are already taking. Do not start or stop taking any drug or change the dosage without your doctor’s advice.

What do I need to know or do while taking this drug?

• Tell all your health care workers that you are taking this drug. These are doctors, nurses, pharmacists and dentists.
• Tell your doctor if you are breastfeeding. It is necessary to consult whether the drug poses any risk to the child.

What side effects should I report to my doctor immediately?

WARNING. In rare cases, this drug can cause serious and sometimes deadly side effects in some patients. Contact your doctor or seek medical attention right away if you have any of the following signs or symptoms that may be associated with serious side effects:

• Signs of an allergic reaction, such as rash, hives, itching, red and swollen skin with blisters or peeling, possibly accompanied by fever, wheezing or wheezing, tightness in the chest or throat, difficulty breathing, swallowing or speaking, unusual hoarseness, swelling in the mouth, face, lips, tongue or throat.
• Signs of a urinary tract infection, including blood in the urine, burning or painful urination, frequent or immediate urge to urinate, fever, pain in the lower abdomen or pelvis.

What are some other side effects of this drug?

Any medicine can have side effects. However, for many people, side effects are either minor or non-existent. Talk to your doctor or get medical help if these or any other side effects bother you or don’t go away:

• Abdominal pain or diarrhea.
• Nausea or vomiting.
• Dizziness or headache.
• Feeling tired or weak.

This list of possible side effects is not exhaustive. If you have any questions about side effects, please contact your doctor. Talk to your doctor about side effects.

You can report side effects to the National Health Board.

You can report side effects to the FDA at 1-800-332-1088. You can also report side effects at https://www.fda.gov/medwatch.

What is the best way to take this drug?

Use this drug as directed by your doctor. Read all the information provided to you. Strictly follow all instructions.

• Take this drug with or without food.
• Take the drug at intervals of approximately 12 hours.

What if I miss a dose of a drug?

• Take the missed dose as soon as you can.
• If it’s time for your next dose, don’t take the missed dose and then go back to your regular dosing schedule.
• Do not take 2 doses or an additional dose at the same time.

How do I store and/or discard this drug?

• Store at room temperature in a dry place. Do not store in the bathroom.
• Keep all medicines in a safe place. Keep all medicines out of the reach of children and pets.
• Dispose of unused or expired drugs. Do not empty into a toilet or sewer unless instructed to do so. If you have any questions about disposing of medicines, ask your pharmacist. Drug disposal programs may be in place in your area.

General information about medicines

• If your health does not improve or even worsens, see your doctor.
• Do not give your medicine to anyone and do not take other people’s medicines.
• Some medicines may come with other patient information leaflets. If you have questions about this drug, talk with your doctor, nurse, pharmacist, or other health care professional.
• A separate instruction for patients is attached to the drug. Please read this information carefully. Reread it each time you refill your supply. If you have any questions about this drug, ask your doctor, pharmacist, or other health care professional.
• If you think you have overdosed, call a poison control center or get medical help right away. Be prepared to tell or show what drug you took, how much, and when it happened.

Consumer Use of Information and Limitation of Liability

This summary information includes a summary of the diagnosis, treatment, and/or drug product. It is not intended to be a comprehensive source of data and should be used as a tool to help the user understand and/or evaluate potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a particular patient. It should not be considered medical advice or a substitute for medical advice, diagnosis or treatment provided by a physician based on a medical examination and assessment of the patient’s specific and unique circumstances. Patients should consult with their physician for full information about their health, medical issues, and treatment options, including any risks or benefits regarding the use of medications. This information is not a guarantee that a treatment or drug is safe, effective, or approved for a particular patient. UpToDate, Inc. and its subsidiaries disclaim any warranties or liabilities related to this information or its use. The use of this information is subject to the Terms of Use found at https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms.

Last revision date

2022-12-07

Copyright

© UpToDate, Inc. and its affiliates and/or licensors, 2023. All rights reserved.

Date last updated

Monday, December 12, 2022

Antifungal Market Size Forecast (2022-27)

Antifungal Market Size Forecast (2022-27) | Industry Analysis

Market Review

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Market Review

Antifungal drugs market is expected to grow by 3.5% on average during the study period.

The COVID-19 epidemic has had a strong impact on the market. As import and export operations are limited due to job closures, the market has been significantly impacted by shortages and lack of consumer goods and supplies. However, this allowed local producers to increase their presence in the market. Supply disruptions and shortages of medical supplies have been observed in a number of countries due to temporary closures of production facilities, export restrictions, increased demand for COVID-19 drug, as well as the collection of medicines by individuals.

Governments have taken a number of steps in response to supply chain disruptions. For example, the European Medicines Agency has issued guidance to pharmaceutical companies on the regulatory framework to deal with this epidemic. These measures were aimed at reducing the impact of the epidemic on production and supply. Now, 2020 reports are emerging suggesting that about a third of patients with severe COVID-19 infectionneed intensive care that can fight another deadly infection: aspergillosis, a deadly fungal infection caused by the fungus Aspergillus. Thus, the researchers found that patients with COVID-19 may be at greater risk of lung infections caused by fungal respiration. Therefore, scientists are working on further research in this area. During the second wave of COVID-19 infection in India, scientists began to diagnose mucormycosis in patients with COVID-19. In May 2021, the Director General of Medicines India (DCGI) withdrew applications from five companies that make the antifungal drug, amphotericin B, which is used to treat mucormycosis. Thus, this epidemic situation is expected to lead to an increase in demand for OTC drugs in the short term, but a decrease in the number of drugs and drugs for diagnosing disruptions in the medical supply chain may lead to a temporary downturn in the market.

Key factors driving the growth of the antifungal market include increased awareness of many fungal infections, an increase in over-the-counter antiretroviral (OTC) drugs, and increased use of antimicrobials in developing countries. With the rise in popularity of over-the-counter (OTC) drugs such as clotrimazole, econazole, ketoconazole, miconazole, and amorolfine, many patients take over-the-counter (OTC) drugs to obtain a prescription from a healthcare professional. An increase in the number of cases of onychomycosis, a fungal infection of the fingers and toes, is also expected to boost market growth. For example, according to an article published by Myron A. Bodman at the National Institutes of Health in 2020, onychomycosis is on the rise worldwide, with prevalence rates ranging from 1% to 8% of total nail infections. In addition to the same source, patients are prone to dermatophyte infections in an autosomal dominant pattern, and risk factors associated with this condition are aging, diabetes, tinea pedis, psoriasis, and lack of immunity among others. In addition, according to the article “High prevalence of mixed diseases in global onychomycosis” published in September 2020, the worldwide prevalence of onychomycosis is estimated at 10%, and the most contagious organism is Trichophyton rubrum. An increase in the burden of diseases such as onychomycosis is expected to boost market growth during the forecast period. According to the article “High prevalence of mixed diseases in global onychomycosis”, published in September 2020, the prevalence of onychomycosis worldwide is estimated at 10%, and the most contagious microorganism is Trichophyton rubrum. An increase in the burden of diseases such as onychomycosis is expected to boost market growth during the forecast period. According to the article “High prevalence of mixed diseases in global onychomycosis”, published in September 2020, the prevalence of onychomycosis worldwide is estimated at 10%, and the most contagious microorganism is Trichophyton rubrum. An increase in the burden of diseases such as onychomycosis is expected to boost market growth during the forecast period.

Report scope

For the purposes of this report, antifungals refer to drugs used/prescribed to treat diseases caused by fungi.

The antifungal drugs market is segmented by drug type (echinocandins, azoles, polyenes, allylamines and other types of drugs), indication (aspergillosis, dermatophytosis, candidiasis and other indications), dosage form (powder, ointments, tablets and other dosages). Forms) and by geography (North America, Europe, Asia Pacific, Middle East and Africa, and South America). The market report also covers estimated market sizes and trends for 17 different countries in major regions of the world . The report proposes the value (in billions of US dollars) for the above segments.

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Key Market Trends

The Azoles segment is expected to be one of the main market players

Antifungal drug research is gaining momentum with the development of new antifungal drugs using the azole group. Synthetic azoles and semi-synthetic compounds are widely used in more fungal infections and infections. These drugs are used to treat thrush, yeast infection, candidiasis, aspergillosis, pityriasis versicolor, athlete’s foot, itching, ringworm, fungal infections, systemic athlete’s foot, and seborrheic dermatitis. . The antifungal group of azoles includes the biphasic triazoles (fluconazole, itraconazole, voriconazole, posaconazole, and isavuconazole) and midazols (ketoconazole). Triazoles have a wide range of applications in the treatment of external and systemic mycoses. The azole group provides a broad spectrum of activity and improved safety standards. The drugs have fewer side effects, worse drug interactions, and improved absorption and distribution properties. The aforementioned benefits of azoles contributed to their control over other components. Soazoles are currently the most widely used and widely read class of antifungals. Medicines are available in various forms (capsules, cream, sterile intravenous solution, ingredient, vaginal cream and tablets).

The development and innovation of such potential drugs contributes to the competitiveness of the pharmaceutical market. Your sale of both established agents and new antifungal agents is important. In addition, in 2019, Mayne Pharma announced the launch of TOLSURA (Suba-itraconazole) 65 mg capsules in the US. TOLSURA is an itraconazole formulation that has been shown to treat systemic fungal infections including blastomycosis, histoplasmosis, aspergillosis and others. Thus, all these factors are expected to contribute to partial growth in the forecast period.

However, problems have already been reported, such as growing tensions between Candida and Aspergillus species, especially with respect to azoles, which are believed to be caused by the use of azoles in agriculture. Many developed countries are also experiencing high infection rates, which is expected to boost market demand.

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North America is expected to account for the largest market share

The USA is one of the most economically developed countries in the world. It currently occupies a large part of the market. Fungal infections in the US have created problems for the country’s health authorities. According to the Centers for Disease Control and Prevention (CDC), resistance to certain strains of Candida (which is a common cause of blood-related infections in the United States) has been noted. About 7% of all blood flow tests for Candida at the CDC are not fluconazole resistant. This view has remained unchanged over the past two decades. However, resistance to echinocandin has increased. In addition, drug-resistant strains are widespread in the country. In addition, the number of aging people in the United States is on the rise. According to the World Population Aging 2019 report, about 53. By 2019, 340 people aged 65 and over are expected to reach 70,842 by 2030, about 20% of the country’s population. This population is more susceptible to chronic diseases such as cancer and therefore damage to the immune system. Consequently, the population may be more susceptible to fungal infections, which will create a need for antifungal drugs in the country. This population is more susceptible to chronic diseases, which puts the immune system at risk. Consequently, the population is more susceptible to fungal infections, which will create a need for antifungal drugs in the country. Morbidity and mortality associated with fungal infections have remained virtually unchanged for more than a decade, despite significant advances in the treatment of fungi.

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Competitive environment

The studied market is moderately consolidated due to the presence of several small and several very large players. Some of the market players are Abbott Laboratories, Bayer AG, Astellas Pharma Inc., Glenmark, GlaxoSmithKline PLC, Merck & Co. Inc., Novartis AG, Pfizer Inc. etc.

Major Players

1. Abbott Laboratories

2. Bayer AG

3. GlaxoSmithKline Plc

4. Merck & Co., Inc.

5. Glenmark

*Disclaimer: Major Players sorted in no particular order

Table of Contents

2. 1.2 Scope of the Study

900 05

6.1.6 Arcadia Consumer Healthcare

**Competitive Landscape covers- Business Overview, Financials, Products and Strategies and Recent Developments

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Frequently Asked Questions

What is the study period for this market?

The global antifungal market is being studied from 2018 to 2028.