What are the common side effects of Zoloft (Sertraline). How can patients manage potential allergic reactions to Sertraline. What are the serious side effects that require immediate medical attention. How does Sertraline affect sleep patterns and mood.

Common Side Effects of Sertraline: What to Expect

Sertraline, commonly known by its brand name Zoloft, is a widely prescribed antidepressant. While it’s effective for many, it’s crucial to be aware of potential side effects. Common side effects affect more than 1 in 100 people and often improve as the body adjusts to the medication.

• Nausea
• Headaches
• Insomnia
• Drowsiness
• Diarrhea
• Dry mouth
• Dizziness
• Fatigue or weakness

Is nausea a common side effect of Sertraline? Yes, nausea is one of the most frequently reported side effects. To manage this, try taking Sertraline with food or after meals. Avoiding rich or spicy foods may also help alleviate nausea symptoms.

Managing Sleep-Related Side Effects of Zoloft

Sertraline can significantly impact sleep patterns, causing either insomnia or excessive sleepiness. These effects can be disruptive to daily life, but there are strategies to manage them effectively.

Dealing with Insomnia

For those experiencing difficulty falling asleep, taking Sertraline in the morning may help. This timing allows the medication to be metabolized throughout the day, potentially reducing its impact on sleep at night.

Coping with Daytime Drowsiness

If drowsiness is an issue, consider these steps:

1. Take Sertraline in the evening to align peak drowsiness with bedtime.
2. Reduce alcohol consumption, as it can exacerbate drowsiness.
3. Avoid driving or operating machinery when feeling sleepy.
4. Consult your doctor if drowsiness persists or significantly impacts daily activities.

How long do sleep-related side effects typically last? Many patients find that sleep disturbances improve within the first few weeks of treatment as their body adjusts to the medication. However, if problems persist beyond this period, it’s important to discuss them with a healthcare provider.

Gastrointestinal Effects: Diarrhea and Dry Mouth

Gastrointestinal side effects are common with Sertraline use. Two of the most frequently reported are diarrhea and dry mouth. While these can be uncomfortable, there are ways to manage them effectively.

Managing Diarrhea

Diarrhea can lead to dehydration if not properly managed. Here are some steps to take:

• Drink plenty of fluids to prevent dehydration.
• Watch for signs of dehydration such as decreased urination or dark, strong-smelling urine.
• Consult a healthcare provider before taking any anti-diarrheal medications.
• For women on oral contraceptives, be aware that severe diarrhea lasting more than 24 hours may reduce contraceptive effectiveness.

Alleviating Dry Mouth

Dry mouth, while less severe, can be uncomfortable. To manage this side effect:

• Chew sugar-free gum or suck on sugar-free candies to stimulate saliva production.
• Stay hydrated by drinking water regularly throughout the day.
• Use a humidifier to add moisture to the air, especially while sleeping.
• Consider using over-the-counter saliva substitutes if the problem persists.

Can long-term use of Sertraline lead to chronic gastrointestinal issues? While most gastrointestinal side effects are temporary and resolve as the body adjusts to the medication, some individuals may experience persistent symptoms. In such cases, it’s crucial to consult with a healthcare provider to explore potential solutions or alternative treatments.

Recognizing and Responding to Serious Side Effects

While rare, serious side effects can occur with Sertraline use. It’s crucial to be aware of these potential reactions and know when to seek immediate medical attention.

Symptoms Requiring Prompt Medical Consultation

• Changes in menstrual periods (heavy bleeding, spotting)
• Unexplained weight changes
• Feelings of extreme happiness or restlessness
• Yellowing of eyes or skin (signs of liver problems)
• Blood in cough, urine, or stool
• Unusual bleeding or bruising

Emergency Situations

Certain symptoms require immediate emergency care. Call emergency services or go to the nearest emergency room if you experience:

• Chest pain or pressure
• Severe headaches or cognitive difficulties
• Suicidal thoughts
• Severe dizziness or fainting
• Prolonged, painful erections
• Uncontrollable bleeding

How quickly do serious side effects typically manifest? The onset of serious side effects can vary. Some may develop rapidly within hours or days of starting the medication, while others might emerge gradually over weeks or months. This underscores the importance of regular check-ups and open communication with healthcare providers throughout the course of treatment.

Understanding Sertraline’s Impact on Mood and Anxiety

Sertraline is primarily prescribed to treat depression and anxiety disorders. However, its effects on mood can be complex, especially in the initial stages of treatment.

Initial Worsening of Anxiety

Some individuals, particularly those taking Sertraline for panic attacks, may experience an initial increase in anxiety symptoms. This paradoxical reaction typically occurs during the first few weeks of treatment.

Why does anxiety sometimes worsen initially with Sertraline? This temporary increase in anxiety is thought to be due to the body’s adjustment to the medication. As Sertraline begins to affect neurotransmitter levels in the brain, it can cause a temporary imbalance that may manifest as increased anxiety. However, this effect usually subsides as the body adapts to the medication.

Managing Mood Fluctuations

• Be patient and allow time for the medication to take effect (usually 4-6 weeks).
• Keep a mood journal to track changes and patterns.
• Communicate regularly with your healthcare provider about mood changes.
• Consider complementary therapies like cognitive-behavioral therapy (CBT) to enhance treatment efficacy.

Is it normal to experience mood swings while on Sertraline? Some mood fluctuations are common, especially in the early stages of treatment. However, severe mood swings, particularly those involving extreme highs (mania) or suicidal thoughts, should be reported to a healthcare provider immediately.

Allergic Reactions to Sertraline: Identification and Response

While rare, allergic reactions to Sertraline can occur and may be severe. Recognizing the signs of an allergic reaction and knowing how to respond is crucial for patient safety.

Symptoms of Allergic Reactions

• Skin rash (may be itchy, red, swollen, blistered, or peeling)
• Wheezing or difficulty breathing
• Tightness in the chest or throat
• Swelling of the face, lips, tongue, or throat
• Severe dizziness or fainting

Immediate Response to Allergic Reactions

If you suspect an allergic reaction to Sertraline:

1. Stop taking the medication immediately.
2. Seek emergency medical attention (call emergency services or go to the nearest emergency room).
3. If prescribed, use an epinephrine auto-injector (EpiPen) for severe reactions.
4. Inform all healthcare providers about the allergy in future medical situations.

How common are allergic reactions to Sertraline? Severe allergic reactions (anaphylaxis) to Sertraline are rare, affecting less than 1 in 1000 patients. However, milder allergic responses, such as skin rashes, may be more common. It’s important to report any suspected allergic symptoms to a healthcare provider promptly.

Long-Term Effects and Considerations for Sertraline Use

While Sertraline is generally considered safe for long-term use, it’s important to be aware of potential long-term effects and considerations for extended treatment.

Potential Long-Term Effects

• Sexual side effects (decreased libido, difficulty achieving orgasm)
• Weight changes
• Increased risk of bone fractures in older adults
• Potential for developing tolerance or dependence

Monitoring and Management

For individuals on long-term Sertraline therapy:

• Regular check-ups with healthcare providers to assess ongoing efficacy and side effects
• Periodic blood tests to monitor liver function and electrolyte levels
• Discussion of any plans for pregnancy, as Sertraline may affect fetal development
• Consideration of gradual dose reduction if discontinuation is planned, to minimize withdrawal symptoms

Does long-term use of Sertraline lead to permanent changes in brain chemistry? Current research suggests that while Sertraline does alter brain chemistry during use, these changes are generally not permanent. Most effects reverse after discontinuation of the medication. However, the long-term impact can vary among individuals, and more research is needed in this area.

Interactions and Precautions: Maximizing Sertraline Safety

Understanding potential drug interactions and necessary precautions is crucial for safe and effective use of Sertraline.

Common Drug Interactions

Sertraline can interact with various medications and substances, including:

• Other antidepressants, particularly MAOIs
• Blood thinners (e.g., warfarin)
• NSAIDs (e.g., ibuprofen, aspirin)
• Certain migraine medications
• St. John’s Wort and other herbal supplements

Special Precautions

Certain groups should exercise extra caution when using Sertraline:

• Pregnant or breastfeeding women
• Elderly patients
• Individuals with liver or kidney disease
• Those with a history of seizures or bipolar disorder
• Patients undergoing electroconvulsive therapy (ECT)

How does alcohol consumption affect Sertraline efficacy and side effects? Alcohol can increase the sedative effects of Sertraline, leading to enhanced drowsiness and impaired coordination. It may also exacerbate side effects like dizziness and nausea. Additionally, alcohol can worsen depression symptoms, potentially counteracting the therapeutic effects of Sertraline. It’s generally advised to limit or avoid alcohol consumption while taking this medication.

In conclusion, while Sertraline (Zoloft) is an effective treatment for depression and anxiety disorders, it’s crucial to be aware of potential side effects, allergic reactions, and necessary precautions. By understanding these aspects and maintaining open communication with healthcare providers, patients can maximize the benefits of Sertraline while minimizing risks. Regular monitoring, prompt reporting of concerning symptoms, and adherence to medical advice are key to safe and effective long-term use of this medication.

Side effects of sertraline – NHS

Like all medicines, sertraline can cause side effects in some people, but many people have no side effects or only minor ones.

Some of the common side effects of sertraline will gradually improve as your body gets used to it.

Some people who take sertraline for panic attacks find their anxiety gets worse during the first few weeks of treatment. This usually wears off after a few weeks, but speak to your doctor if it bothers you. A lower dose may help reduce your symptoms.

Common side effects

These common side effects of sertraline happen in more than 1 in 100 people. There are things you can do to help cope with them:

Feeling sick (nausea)

Try taking sertraline with or after food. It may also help if you avoid rich or spicy food.

Headaches

Make sure you rest and drink plenty of fluids. It’s best not to drink too much alcohol. Ask your pharmacist to recommend a painkiller. Headaches should usually go away after the first week of taking sertraline. Talk to your doctor if they last longer than a week or are severe.

Being unable to sleep

Take sertraline first thing in the morning.

Feeling sleepy

Take sertraline in the evening and cut down the amount of alcohol you drink. Do not drive, ride a bike or use tools or machinery if you’re feeling sleepy. If this does not help, talk to your doctor.

Diarrhoea

Drink plenty of water or other fluids to avoid dehydration. Signs of dehydration include peeing less than usual and having dark, strong-smelling pee. Do not take any other medicines to treat diarrhoea without speaking to a pharmacist or doctor.

If you take contraceptive pills and you have severe diarrhoea for more than 24 hours, your contraception may not protect you from pregnancy. Check the pill packet for advice.

Dry mouth

Chew sugar-free gum or suck sugar-free sweets.

Feeling dizzy

If sertraline makes you feel dizzy, stop what you’re doing and sit or lie down until you feel better.

Feeling tired or weak

If sertraline makes you feel tired or weak, stop what you’re doing and sit or lie down until you feel better. Do not drive, ride a bike or use tools or machinery if you’re feeling tired.

It’s best not to drink alcohol as it will make you feel worse. If these symptoms do not go away after 1 or 2 weeks, ask your pharmacist or doctor for advice.

Keep taking the medicine, but speak to a doctor or pharmacist if the advice on how to cope does not help and a side effect is still bothering you or does not go away.

Serious side effects

It happens rarely (in less than 1 in 100 people), but some people may have serious side effects when taking sertraline.

Book an appointment with your doctor if you get:

• changes in your periods, such as heavy bleeding, spotting or bleeding between periods
• weight gain or weight loss without trying

Call a doctor or contact 111 now if:

• you have feelings of overwhelming happiness (euphoria), excessive enthusiasm or excitement, or a feeling of restlessness that means you cannot sit or stand still
• the whites of your eyes turn yellow, or your skin turns yellow (this may be less noticeable on brown or black skin) – these can be signs of liver problems
• you cough up blood or have blood in your pee
• you have black or red poo or blood in your vomit – these can be signs of bleeding from the gut
• you are bleeding from the gums, or get bruises that appear without a reason or that get bigger

Go to 111. nhs.uk or call 111.

Immediate action required: Call 999 or go to A&E now if you:

• get chest pain or pressure, or shortness of breath
• get headaches, have trouble focusing, have memory problems, cannot think clearly, have weakness, have a seizure or fit, or lose your balance – these can be signs of low sodium levels
• have thoughts about harming yourself or ending your life
• get severe dizziness or pass out
• get painful erections that last longer than 2 hours – this may happen even when you’re not having sex
• get any heavy bleeding or bleeding that you cannot stop, such as cuts or nosebleeds that do not stop within 10 minutes

Serious allergic reaction

In rare cases, it’s possible to have a serious allergic reaction (anaphylaxis) to sertraline.

Immediate action required: Call 999 or go to A&E now if:

• you get a skin rash that may include itchy, red, swollen, blistered or peeling skin
• you’re wheezing
• you get tightness in the chest or throat
• you have trouble breathing or talking
• your mouth, face, lips, tongue or throat start swelling

You could be having a serious allergic reaction and may need immediate treatment in hospital.

Long-term side effects

A few people may get sexual side effects, such as problems getting an erection or a lower sex drive. In some cases these can continue even after stopping the medicine. Speak to your doctor if you are worried.

Taking sertraline for more than a year has also been linked to a small increased risk of getting diabetes. You’ll be regularly checked for this.

Other side effects

These are not all the side effects of sertraline. For a full list, see the leaflet inside your medicine packet.

Information:

You can report any suspected side effect using the Yellow Card safety scheme.

Visit Yellow Card for further information.

Page last reviewed: 2 February 2022

Next review due: 2 February 2025

What They Are and How to Manage Them

Zoloft (sertraline) is a prescription drug used to help treat certain mental health conditions. It can cause side effects that range from mild to serious. Examples include thoughts of suicide, nausea, tremors, and sexual side effects.

Zoloft is used in adults to treat:

• major depressive disorder
• panic disorder
• post-traumatic stress disorder (PTSD)
• premenstrual dysphoric disorder
• social anxiety disorder

Zoloft is also used in adults and some children to treat obsessive-compulsive disorder (OCD).

The active ingredient in Zoloft is sertraline. (An active ingredient is what makes a drug work.) The drug comes as a tablet and an oral solution, both of which you swallow.

Zoloft has several reported side effects, ranging from mild to severe. But not all people who take Zoloft will experience side effects.

Keep reading to learn about the common, mild, and serious side effects this drug can cause. For a general overview of Zoloft, including details about its uses, see this article.

Some people may experience mild to serious side effects during their Zoloft treatment.

Examples of the drug’s commonly reported side effects include:

• diarrhea
• nausea
• tremors
• decreased appetite
• sexual side effects* such as:
  • erectile dysfunction (problems getting or keeping an erection)
  • trouble reaching orgasm
  • decreased sex drive

* To learn more about this side effect, see the “Side effects explained” section below.

These are just a few of the possible side effects Zoloft may cause. But not everyone who takes Zoloft will experience side effects. Keep reading to learn about other potential side effects of this drug.

Most of the possible side effects of Zoloft are mild and will resolve with treatment.

Examples of mild side effects reported in studies include:

• nausea
• diarrhea
• tremors
• decreased appetite
• indigestion (upset stomach)
• dizziness
• excessive sweating
• dry mouth
• trouble sleeping
• sleepiness
• constipation
• vomiting
• sexual side effects* such as:
  • erectile dysfunction (problems getting or keeping an erection)
  • trouble reaching orgasm
  • decreased sex drive*
• mild allergic reaction*

* To learn more about this side effect, see the “Side effects explained” section below.

In most cases, these side effects should be temporary. And some may be easily managed. But if you have symptoms that are ongoing or bothersome, talk with your doctor or pharmacist. And do not stop taking Zoloft unless your doctor recommends it.

Zoloft may cause mild side effects other than those listed above. See the drug’s prescribing information for details.

Serious side effects from Zoloft are rare but possible. If you develop serious side effects while taking this drug, call your doctor right away. If the side effects seem life threatening or you think you’re having a medical emergency, immediately call 911 or your local emergency number.

Examples of serious side effects that have been reported with Zoloft include:

• closed-angle glaucoma
• seizure
• low sodium levels
• long QT syndrome
• manic episodes*
• increased risk of bleeding*
• serotonin syndrome (a high level of the chemical serotonin)*
• risk of suicidal thoughts and behaviors†
• severe allergic reaction*

* To learn more about this side effect, see the “Side effects explained” section below.
† Zoloft has a boxed warning for this side effect. This is the most serious warning from the Food and Drug Administration (FDA). To learn more, see the “Side effects explained” section below.

Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. If you’d like to notify the FDA about a side effect you’ve had with Zoloft, visit MedWatch.

Help is out there

If you or someone you know is in crisis and considering suicide or self-harm, please seek support:

• Call the 988 Suicide and Crisis Lifeline at 988.
• Text HOME to the Crisis Textline at 741741.
• Not in the United States? Find a helpline in your country with Befrienders Worldwide.
• Call 911 or your local emergency services number if you feel safe to do so.

If you’re calling on behalf of someone else, stay with them until help arrives. You may remove weapons or substances that can cause harm if you can do so safely.

If you are not in the same household, stay on the phone with them until help arrives.

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Zoloft is used to help treat obsessive-compulsive disorder (OCD) in children ages 6 years and older. The possible side effects of Zoloft in children are similar to those listed above for adults. Zoloft has a boxed warning for increased risk of suicidal thoughts and behaviors. (See the “Side effects explained” section below for more information.)

Zoloft may cause your child to have a decreased appetite. This could lead to weight loss and may affect their height and weight growth. Talk with your child’s doctor for more information. They’ll likely monitor your child’s growth if your child needs to take Zoloft long-term.

Get answers to some frequently asked questions about Zoloft’s side effects.

How do side effects of Zoloft in women compare with those in men?

Most Zoloft side effects are similar for males* and females.* But Zoloft’s sexual side effects are different for males and females. Males have an increased risk of erectile dysfunction (problems getting or keeping an erection) and delayed ejaculation (needing more than 30 minutes of sexual stimulation to ejaculate) or failure to ejaculate. Females have an increased risk of trouble reaching orgasm. Both males and females who take Zoloft may have a lower sex drive than usual.

* In this article, we use the terms “male” and “female” to refer to someone’s sex assigned at birth. For information about the difference between sex and gender, see this article.

Will I experience certain side effects of Zoloft during the first week of treatment?

You may be more likely to experience certain side effects during your first week of Zoloft treatment. This is because your body is getting used to the drug. Some common early side effects of Zoloft include headache, nausea, fatigue, and constipation.

Also, keep in mind that Zoloft can increase the risk of suicidal thoughts and behaviors, and this risk may be higher during the first few months of treatment. *

This is not a complete list of side effects, and not all people will experience these side effects. Talk with your doctor for more information.

* Zoloft has a boxed warning for this side effect. This is the most serious warning from the Food and Drug Administration (FDA). To learn more, see the “Side effects explained” section below.

Can Zoloft cause long-term side effects?

Most Zoloft side effects resolve when they are treated or when Zoloft is stopped. Talk with your doctor if you experience side effects. They’ll decide if it’s safe for you to keep taking Zoloft or whether another treatment might be better.

Do not stop taking Zoloft without talking with your doctor first. Stopping this drug suddenly may cause side effects such as dizziness, tremor, nausea, sweating, and mood changes. Talk with your doctor about other possible side effects of stopping Zoloft.

How long does it take for side effects of Zoloft to go away?

Most Zoloft side effects should resolve quickly when they are treated or when Zoloft is stopped. Some side effects may resolve on their own as your body adjusts to the medication. Talk with your doctor about any bothersome side effects. They’ll recommend the best treatment for them.

Does Zoloft cause weight gain?

Weight gain is not a reported side effect of Zoloft in studies. Decreased appetite is a common side effect of this drug that may lead to weight loss. But the condition you’re using Zoloft to treat may lead to weight gain. Talk with your doctor if your weight has changed while taking Zoloft.

Learn more about some of the side effects Zoloft may cause.

Risk of suicidal thoughts and behaviors

Zoloft has a boxed warning for the risk of suicidal thoughts and behaviors in children and adults ages 24 years and younger.* A boxed warning is the most serious warning from the Food and Drug Administration (FDA). It alerts doctors and patients about drug effects that may be dangerous.

Though this side effect was rare in studies, the risk is highest in the first few months of Zoloft treatment or after a change in dosage. Due to this risk, your doctor will monitor you closely for suicidal thoughts and behaviors.

* Zoloft is not prescribed for anyone under the age of 6 years.

What might help

Talk with your doctor right away if you feel like your condition is worsening or you have thoughts of hurting yourself. Call 911 or your local emergency number if you are hurt or need help immediately.

Sexual side effects

Zoloft may cause sexual side effects, such as:

• erectile dysfunction (problems getting or keeping an erection)
• trouble reaching orgasm
• decreased sex drive

These were common side effects in the drug’s studies.

What might help

Tell your doctor if you have any changes in sex drive or other problems during sex that are bothersome. They’ll help you determine whether Zoloft is the cause. If it is, they may recommend a different treatment for your condition.

Increased risk of bleeding

You may have an increased risk of bleeding if you take certain other drugs while taking Zoloft. Some of these drugs include:

• warfarin
• aspirin
• nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen

Types of bleeding to tell your doctor about include:

• nosebleeds
• bruising easily
• bleeding gums
• vomiting blood
• bloody or dark, tarry stools

What might help

Tell your doctor before starting or stopping any medications. They’ll monitor you closely if you’re prescribed drugs that can interact with Zoloft. And they can recommend a different treatment option if it’s not safe for you to take Zoloft.

Mania

If you have bipolar disorder and take Zoloft, you may have an increased risk of manic episodes. This was rarely reported, but that’s because people with bipolar disorder were usually not included in the drug’s studies.

Symptoms of a manic episode may include:

• racing thoughts
• excessive levels of excitement, activity, or happiness
• reckless or impulsive behavior
• extreme trouble sleeping
• talking faster or more than usual

What might help

Tell your doctor right away if you experience any of the symptoms above. They’ll recommend the right treatment for you and decide whether it’s safe for you to keep taking Zoloft.

Serotonin syndrome

A rare but serious side effect reported in studies of Zoloft is serotonin syndrome. This is a condition caused by a high level of the chemical serotonin in your body. You may have an increased risk of this side effect if you take certain other medications, but it can also happen if you only take Zoloft.

Symptoms of serotonin syndrome include:

• fast heart rate
• flushing (temporary warmth, redness, or deepening of skin color)
• sweating
• nausea
• vomiting
• diarrhea
• hallucinations (hearing or seeing things that aren’t really there)
• agitation (nervousness, annoyance, or anger)

What might help

Tell your doctor right away if you have any of the symptoms listed above. They’ll likely have you stop taking Zoloft and treat your symptoms. They’ll also likely prescribe a different treatment for your condition.

Allergic reaction

Like most drugs, Zoloft can cause an allergic reaction in some people.

Symptoms can be mild to serious and can include:

• skin rash
• itchiness
• flushing (temporary warmth, redness, or deepening of skin color)
• swelling under your skin, usually in your eyelids, lips, hands, or feet
• swelling of your mouth, tongue, or throat, which can make it hard to breathe

What might help

If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away. They may suggest a treatment to manage your symptoms. Examples include:

• an antihistamine you swallow, such as Benadryl (diphenhydramine)
• a product you apply to your skin, such as hydrocortisone cream

If your doctor confirms you’ve had a mild allergic reaction to Zoloft, they’ll decide whether you should continue taking it.

If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away. These symptoms could be life threatening and require immediate medical care.

If your doctor confirms you’ve had a serious allergic reaction to Zoloft, they may have you switch to a different treatment.

Keeping track of side effects

During your Zoloft treatment, consider taking notes on any side effects you’re having. You can then share this information with your doctor. This is especially helpful when you first start taking a new drug or using a combination of treatments.

Your side effect notes can include things such as:

• what dose of the drug you were taking when you had the side effect
• how soon you had the side effect after starting that dose
• what your symptoms were
• how your symptoms affected your daily activities
• what other medications you were taking
• any other information you feel is important

Keeping notes and sharing them with your doctor will help them learn more about how Zoloft affects you. They can then use this information to adjust your treatment plan if needed.

Talk with your doctor about your health history before starting Zoloft. Factors to consider include those described below.

Boxed warning: Risk of suicidal thoughts and behaviors

Zoloft has a boxed warning for the risk of suicidal thoughts and behaviors. A boxed warning is the most serious warning from the FDA. Children and adults ages 24 years and younger are at risk of suicidal thoughts and behaviors while taking this drug. To learn more, see the “Side effects explained” section above.

Other warnings

Zoloft may not be right for you if you have certain medical conditions. This is known as a drug-condition interaction. Below are conditions and other factors that may affect whether this drug is a good treatment option for you.

Seizure disorder. If you have a seizure disorder, you may have an increased risk of seizures when taking Zoloft. Due to this risk, your doctor will likely not prescribe this drug for you. Ask them about other treatments that might be better options.

Allergic reaction. If you’ve had an allergic reaction to Zoloft or any of its ingredients, your doctor will likely not prescribe it for you. Ask them about other medications that might be better options.

Bipolar disorder. If you have bipolar disorder and take Zoloft, you may have an increased risk of manic episodes. Due to this risk, your doctor will likely not prescribe this drug for you. Ask about other treatments that might be better options.

Closed-angle glaucoma. If you have closed-angle glaucoma and take Zoloft, you may have an increased risk of your condition worsening. Due to this risk, your doctor will likely not prescribe Zoloft for you. Ask them about other medications that might be better options.

Bleeding problems. Taking Zoloft can increase your risk of bleeding. If you already have a bleeding problem, such as hemophilia, Zoloft may worsen it. This risk is also higher if you take medications to prevent blood clots. Talk with your doctor about any health problems you may have and any drugs you take before starting Zoloft. They may prescribe a treatment other than Zoloft for your condition.

Liver problems. Having liver problems can cause Zoloft to build up in your body, which may increase your risk of side effects. Tell your doctor if you have liver problems before starting this drug. They’ll likely prescribe a lower dosage for you.

Low sodium level. Zoloft can lower your blood sodium level. If your sodium level is already low, taking Zoloft can reduce it further. Your doctor will likely check your sodium level with blood tests during your treatment. If it becomes too low, they’ll likely have you stop taking Zoloft and provide treatment to increase your sodium level.

Heart problems. Although this side effect is rare, Zoloft may cause irregular heart rhythm. This risk is higher if you already have heart problems, such as slow heart rate or heart failure. The risk is also higher if you take other drugs that affect your heart rhythm. It’s important to talk with your doctor about your health history and all the medications you take before starting Zoloft. They’ll let you know if this drug is the right treatment for your condition.

Alcohol and Zoloft

There are no reported interactions between alcohol and Zoloft. Talk with your doctor to see whether it’s safe for you to consume alcohol while taking this drug.

Note that you should not take disulfiram (a drug that helps treat alcohol use disorder) with Zoloft oral solution. This is because there is alcohol in this form of Zoloft, and taking it with disulfiram can cause certain side effects, such as nausea and vomiting. You should seek immediate medical attention if this occurs.

Pregnancy and breastfeeding while taking Zoloft

The risk of taking Zoloft while pregnant may depend on how far along your pregnancy is. Studies show that it may be safe to take Zoloft during the first 3 months of pregnancy. The risk of problems with fetal development (commonly known as birth defects) may be low during this time.

But there are potential risks to the fetus if you take Zoloft during the last 3 months of your pregnancy. Once born, your child may experience:

• feeding problems
• breathing problems
• seizure
• hypoglycemia (low blood sugar)
• shaking
• constant crying

But it’s also important to treat your mental health conditions while pregnant. Talk with your doctor before starting Zoloft if you’re pregnant or trying to become pregnant. They’ll help you decide whether you should take Zoloft during this time.

It’s not known whether it’s safe to take Zoloft while breastfeeding. Small amounts of the drug are known to pass through breast milk. And your child has a risk of side effects if you breastfeed them while you’re taking Zoloft. Talk with your doctor about the best treatment option for your mental health condition if you choose to breastfeed your baby.

The common side effects of Zoloft are usually mild and go away when treated or when you stop taking the drug. Although rare, there are some serious and severe side effects to watch out for. If you have questions about side effects that Zoloft can cause, talk with your doctor.

Examples of questions to help get you started include:

• Do I have a higher risk of side effects than others?
• Do any of the other medications I take increase my risk of side effects from Zoloft?
• Does my risk of side effects depend on the dosage of Zoloft that I take?

To learn more about Zoloft, see these articles:

• Zoloft (sertraline)
• Zoloft Interactions: Alcohol, Medications, and Others

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Antidepressant Pfizer Zoloft – “With Zoloft, I seemed to be born again !!!”

Zoloft – this is exactly the drug (like other drugs from the group of antidepressants) before the use of which there is a long and sad history of throwing around doctors, not wanting to live, etc. Anyone who has been in a similar situation (and if you had not been in it, you would not have read the review), he knows what it is.

I met this drug 1.5 years ago . This was preceded by a long story, but I will try to write very briefly:

I got married in 2012. We constantly quarreled with my husband, his mother constantly put sticks in the wheels, indicated what and how we should do: do not take mortgages, do not give birth to children … This is how we lived until 2014. In the morning, after another scandal with my husband, I was pierced by a terrible pain in the lower abdomen. The hospital said that appendicitis and planned to operate only the next morning, because. although the pain remained, it just ached. On the operating table, they cut me open and found that I did not have appendicitis, but a RUPTURE of a cyst. Then the gynecologists were called and there was a difficult operation in 3.5 hours, after which my parents were told: “2-3 decisive days. If he survives them, he will live. ” I didn’t know about it and lay white as death and calmed my crying mother. They prescribed me injections Buserilina (I will write about him later). Then there were a bunch of side effects that do not go away until now !!! Then the second operation. They also removed the cyst. Together with the cysts, they almost completely cut off my ovaries, leaving small pieces. For a year I was treated in the LCD, until one “beautiful” day (as I remember now – January 30) I was told that I would not have children !!! NEVER!!! On the same evening, I “met” panic attacks (although I didn’t know what it was yet). Then I had an allergy, as it turned out, on a nervous basis. I was swollen all over: legs, arms, stomach, neck … I was given injections that seemed to help. Then I was so nervous that my breathing stopped … Yes, my breathing stopped in a dream. After that I stopped sleeping. This went on for a week … For a week without sleep, I no longer understood what was happening and where I was. I had a lump in my throat because I was constantly thinking about swelling. I could no longer go to work, because my breathing stopped even there from the swelling of my throat. Home was better. I had the window open all the time. Panic attacks only became more frequent, I went to the doctors and no one could help me, even neurologists said that I was “healthy”. I came to such a state that I no longer wanted to live. With me, even my mother slept on the bed, because. I was afraid to sleep alone. Suddenly I fall asleep and won’t wake up (I can’t breathe in my sleep). And then I came to an appointment with a therapist for a referral to an allergological hospital, and she told me that I had it on a nervous basis, there was some kind of stress. But I didn’t immediately remember that it all started when they told me that I wouldn’t be able to have children, but I thought about it. But I really screamed during one of the panic attacks: “It seems to me that I am I’M GOING CRAZY “!!! Yes, and one of the allergists said that it was something in my head, and then I thought that it was something in his head, and I threw away so much money for the appointment.

Finally, I got to a normal neurologist who prescribed Zoloft to me, apparently, due to her youth, she prescribed it incorrectly for me and only for 2 months.For my condition, the dosage of 0.25 mg was too large, and even more so for night.So I got even worse, but I did not stop taking it, because I heard that the effect comes only after a month or even later.0005

I despaired again, but then I just found a EXCELLENT psychotherapist who corrected the drug intake (from 0.25 I began to take 2 months to 0.12), and only after that I switched to 0.25 and that was my maximum!

Thanks to the psychotherapist, I drank Zoloft already without side effects (of which there are a whole bunch), we also talked with her first 2 times a week, then 1 time per week, once every two weeks, once a month … I now took Zoloft in the morning at the same time, because he is BRILLIANT!

Today I am slowly giving up Zoloft and, pah-pah-pah, so far so good.

I just came alive! Yes, what came to life there, I was BORN AGAIN! Now I rejoice in the sun and even rain, I find beauty even in an ordinary day. I am very grateful to the psychotherapist and of course Zoloft. And I know if, God forbid, something happens again, I have someone to talk to and something to drink )))))))))

The panic attacks gradually subsided, but the lump in my throat really remained.

I have found a new doctor and have already changed to another one (he invented the infection and treated the invented one for a whole year). The new doctor immediately began to restore my critical days (I have not had them for more than 2 years), and also says that the main thing is to think positively. Despite the fact that all the pills prescribed by doctors make me sooooooo sick: low blood pressure, headaches, weakness, fainting, nausea and vomiting, metallic taste in my mouth and much more, I try to think positively. And I think, of course, God forbid, if I don’t have children, but you can’t fall into such despair !!! The most important thing is health and positive thinking, which is what I wish you!

The description of Zoloft can also be viewed on the Internet, but the review and various stories will only benefit everyone who has encountered problems that simply cannot be dealt with without antidepressants.

Things got better with my husband, but I’m learning to take everything not so close to my heart!

And the most important thing in recovery is to read positive literature! Miscellaneous! A lot of! I read so much in a year that I haven’t read so much in 23 years))) And I still read, but now different literature.

Side effects

From the digestive system: dyspeptic symptoms (flatulence, nausea, vomiting, diarrhea, constipation), abdominal pain, pancreatitis, dry mouth, hepatitis, jaundice, liver failure, loss of appetite ( rarely – increase), up to anorexia; rarely, with prolonged use, an asymptomatic increase in serum transaminase activity occurs. Cancellation of the drug in this case leads to the normalization of enzyme activity.

From the side of the cardiovascular system: palpitations, tachycardia, arterial hypertension.

From the musculoskeletal system: arthralgia, muscle cramps.

From the side of the central nervous system and peripheral nervous system: extrapyramidal disorders (dyskinesia, akathisia, teeth grinding, gait disturbance), involuntary muscle contractions, paresthesia, fainting, drowsiness, headache, migraine, dizziness, tremor, insomnia, anxiety, agitation , hypomania, mania, hallucinations, euphoria, nightmares, psychosis, decreased libido, suicide, coma.

From the respiratory system: bronchospasm, yawning.

From the urinary system: enuresis, incontinence or urinary retention.

From the reproductive system: sexual dysfunction (delayed ejaculation, reduced potency), galactorrhea, gynecomastia, menstrual irregularities, priapism.

From the senses: blurred vision, mydriasis, tinnitus.

From the endocrine system: hyperprolactinemia, hypothyroidism, syndrome of inappropriate ADH secretion.

Dermatological reactions: reddening of the skin or flushing of the face, alopecia, photosensitivity reaction, purpura, increased sweating.

Allergic reactions: urticaria, pruritus, anaphylactoid reaction, angioedema, periorbital edema, facial edema, rarely Stevens-Johnson syndrome and epidermal necrolysis.

From the side of the hematopoietic system: may develop leukopenia and thrombocytopenia.

Other: decrease or increase in body weight, peripheral edema, increase in serum cholesterol, weakness, bleeding (including nasal, gastrointestinal or hematuria). With the termination of treatment with sertraline, rare cases of withdrawal syndrome have been described. Paresthesias, hypesthesias, symptoms of depression, hallucinations, aggressive reactions, psychomotor agitation, anxiety, or symptoms of psychosis that cannot be distinguished from the symptoms of the underlying disease may appear.

Pay no attention to it! The main thing is to get well!

I wish you happiness and a speedy recovery!!!

Zoloft Side Effects: What to Expect During the First Week of Zoloft – Medication Information

Home >> Product Information >> Zoloft Side Effects: What to Expect During the First Week of Zoloft

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Starting dose | Side effects | Missed Dose | Overdose | When to See a Doctor

Living with mental disorders such as anxiety or depression can make everyday life stressful. Fortunately, there are many treatment options for people who want to get rid of anxiety or depression. Zoloft is a prescription medication that is used to reduce the symptoms of anxiety and depression, and when taken properly, it can make everyday life more manageable. Let’s take a closer look at how to take Zoloft, what side effects to watch out for in the first week, and what else to expect when you first start taking this medication.

Launch of Zoloft

Zoloft is the brand name for a generic drug called sertraline, which belongs to a group of drugs called selective serotonin reuptake inhibitors (SSRIs). SSRIs such as Zoloft are antidepressants that increase serotonin levels in the brain. An estimated 31% of all adults will experience an anxiety disorder at some point in their lives, and statistics show that 264 million adults worldwide experience anxiety. Doctors usually Zoloft is prescribed to treat anxiety, but it can also be used to treat depression, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), panic attacks, and premenstrual dysphoric disorder (PMDD).

As with any medicine, it is important to know as much as possible about the medicine you will be taking to make sure you are maximizing its potential benefits. It is important to know how to take Zoloft correctly to ensure that it works as effectively as possible. When taken properly, Zoloft can reduce anxiety or fear in people, as well as decrease the urge to perform repetitive tasks. It can improve sleep quality, appetite, energy levels, restore interest in daily life, and reduce unwanted thoughts and panic attacks.

Zoloft is available as 25 mg, 50 mg or 100 mg tablets. It is also available as an oral solution that must be diluted in four ounces of water, orange juice, lemonade, ginger ale, or lemon-lime soda before use.

The standard dose of Zoloft for anxiety is 25 mg or 50 mg per day. According to the Food and Drug Administration (FDA), these are standard doses of Zoloft for other conditions:

• Major depressive disorder: 50 mg per day
• OCD: 50 mg per day for people over 13 years old
• Panic disorder: 25 mg per day 90 138
• PTSD: 25 mg daily
• Social anxiety disorder: 25 mg per day
• PMDD: 50 mg per day during the luteal phase only

It is important to discuss with your doctor what dosage is right for you because the exact amount of medication you will need will depend on your specific condition, the severity of your symptoms, and whether you have other health problems.

Once you start taking the correct amount of Zoloft, as prescribed by your doctor, you can expect it to start working in about two to six weeks. Zoloft is not the type of medicine that starts working on the first day, so you will need a little patience while you wait until they begin to relieve your symptoms. According to the National Alliance on Mental Illness, some of the first signs that Zoloft is working are improved sleep, energy, or appetite. These improvements may occur as early as one to two weeks after taking the medication. It may take six to eight weeks for more significant changes, such as a reduction in depression or a return to interest in daily life, to appear.

When you first start taking Zoloft, you may notice several side effects. One of the best ways to avoid side effects is to take your medicine exactly as prescribed by your doctor. Your doctor will give you a specific dose for some reason, and taking more Zoloft because you want it to work faster is not safe. Let’s take a look at some of the more common Zoloft side effects that you’ll want to know about when you start taking it.

Zoloft side effects to expect in the first week

During the first week of taking Zoloft, you may experience some initial side effects even if you are taking your medicine exactly as your doctor has told you. This is because it takes time for the body to get used to the drug. Some of the most common side effects that people experience during the first week of taking Zoloft include:

• Headache
• Nausea
• Fatigue
• Constipation
• Dry mouth
• Drowsiness
• Nervousness
• Drowsiness 9013 8
• Sleep problems
• Anxiety
• Decreased sex drive
• Weight gain
• Dizziness
• Loss of appetite
• Increased sweating

While taking Zoloft, you may initially experience discomfort or a strange feeling as your body begins to process the medicine. After a week or two, these side effects will go away for most people as their bodies get used to the medication. Some of these side effects may occur sporadically throughout your Zoloft period, especially if your doctor increases your dose.

Although rare, Zoloft may cause more serious side effects such as:

• Unusual weight loss
• Low sodium
• Increased risk of bleeding
• Eye pain indicative of angle closure glaucoma
• Sexual dysfunction, eg , delayed ejaculation.
• Manic episodes in people with undiagnosed bipolar disorder
• Allergic reactions
• Seizures

Zoloft also comes with a warning for suicidal thoughts and behavior. Short-term studies have shown that antidepressants increase the risk of suicidality in children, adolescents, and young adults compared with placebo. If you are taking Zoloft and experience sudden mood changes and/or suicidal thoughts or behavior, you should seek immediate medical attention.

Another thing to consider when taking Zoloft is that it cannot be taken with certain medications. Giving your doctor a list of all the medications and over-the-counter supplements you are taking will help reduce your chances of more serious side effects from interacting with Zoloft. Here is a list of medicines that should not be taken at the same time as Zoloft:

• Medications that increase serotonin levels
• Triptans (migraine triggers)
• Tricyclic antidepressants
• Blood thinners such as warfarin
• Nonsteroidal anti-inflammatory drugs (NSAIDs)
• St. John’s wort
• Lithium
• Ultram (tramadol)
• Nardil (phenelzine)
• Parnate (tranylcypromine)
• Marplan (isocarboxazid)
• Azilect (rasagiline)
• Emsam (selegiline)
• Orap (pimozide)

Zoloft should not be taken concomitantly with monoamine oxidase inhibitors (MAOIs) because it can lead to serotonin syndrome which causes hallucinations, seizures, coma, tremors, delirium and other serious side effects. This list of drug interactions is not exhaustive, which is why it is important to tell your doctor about all medicines you are taking or plan to take.

Missed dose of Zoloft

No one is perfect, and skipping a dose of Zoloft at one time or another is a must. Taking your medication regularly as directed by your doctor is important, but skipping a dose isn’t the end of the world if you know what to do when it happens.

Take your dose as soon as you remember, says Brian Wind, Ph. D., clinical psychologist and chief clinical officer of JourneyPure. If it’s almost time for your next dose, don’t take an extra dose to make up for the missed one. Just take the next dose. You may experience side effects and an increased risk of relapse if you suddenly stop taking your medication.

Side effects that can occur if you stop or skip medication are mild withdrawal symptoms that occur due to what is called antidepressant withdrawal syndrome. According to American Family Physician , antidepressant withdrawal occurs in about 20% of patients who abruptly stop taking an antidepressant after taking it continuously for at least six weeks. Skipping a dose of Zoloft may cause flu-like symptoms, nausea, insomnia, imbalance, or increased arousal.

The best thing you can do if you miss a dose, as Dr. Wind says, is to take the next dose as soon as you remember. If you experience any symptoms due to the missed dose, they should disappear once you start taking Zoloft regularly again. It may also be a good idea to contact your doctor if you miss a dose, just to check and make sure you don’t have to do anything else.

Zoloft overdose

Zoloft overdose is more serious than skipping a dose. There have been no reported cases of fatal overdose of Zoloft, but taking too much medication can cause serious side effects or health complications. Accidental or intentional ingestion of two or more doses of Zoloft can cause:

• Nausea
• Vomiting
• Dizziness
• Agitation
• Confusion
• Fever
• Syncope

901 35 Hallucinations

• Changes in blood pressure
• Rapid heartbeat
• Tremor
• Convulsions

In rare cases, taking too much amounts of Zoloft can also cause serotonin syndrome, which results in dangerously high levels of the neurotransmitter serotonin in the brain. When there is too much serotonin in the brain, it can cause confusion, diarrhea, and headaches. More severe symptoms may include seizures, hallucinations, muscle stiffness, and coma.

If you think you have overdosed on Zoloft and/or have one or more of these symptoms, you should seek immediate medical attention or call the poison control hotline at 1-800-222-1222 . The Poison Control Hotline is free of charge to all and offers qualified and confidential advice to subscribers.

When to see a doctor about side effects of Zoloft

Zoloft can be an excellent remedy for symptoms of anxiety and depression if taken correctly. Preparing for potential side effects is an important part of taking any medication, and knowing what to expect can alleviate some of the anxiety that often comes with taking a new medication.

If you start taking Zoloft and experience mild side effects, it’s important to remember that this is normal. It is also important to remember at what point you should contact your doctor due to the side effects you are experiencing. As mentioned in this article, more serious side effects such as confusion, hallucinations, allergic reactions, seizures, and vomiting require medical attention. If you begin to experience worsening depression or anxiety, suicidal thoughts, panic attacks, severe irritability or aggression, you should seek immediate medical attention.

Zoloft is not the only antidepressant that treats anxiety and depression. Zoloft can be very effective, but if it doesn’t work for you or causes too many side effects, an alternative antidepressant may be needed. Clinical trials have shown that symptoms of depression disappear completely in about 1 out of every 3 people who take SSRIs, but more research is needed to find out why SSRIs work for some people and not for others.

If you have too many side effects from Zoloft, you may want to discuss other options with your doctor. Here are some of the most popular Zoloft alternatives:

• Celexa (citalopram): Celexa is an FDA-approved SSRI for treating depression, and although it is primarily prescribed for depression, doctors may sometimes prescribe it to relieve symptoms of anxiety.
• Effexor Xr (venlafaxine hydrochloride): Effexor is a serotonin-norepinephrine reuptake inhibitor (SNRI) that can treat depression, improve mood, and increase energy levels.