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Can you get high off cyclobenzaprine: SAMHSA’s National Helpline – 1-800-662-HELP (4357)


SAMHSA’s National Helpline – 1-800-662-HELP (4357)

Frequently Asked Questions

What is SAMHSA’s National Helpline?

SAMHSA’s National Helpline, 1-800-662-HELP (4357), (also known as the Treatment Referral Routing Service) or TTY: 1-800-487-4889 is a confidential, free, 24-hour-a-day, 365-day-a-year, information service, in English and Spanish, for individuals and family members facing mental and/or substance use disorders. This service provides referrals to local treatment facilities, support groups, and community-based organizations. Callers can also order free publications and other information.

Also visit the online treatment locators.

What are the hours of operation?

The service is open 24/7, 365 days a year.

What languages are available?

English and Spanish are available if you select the option to speak with a national representative.

How many calls do you receive?

In 2020, the Helpline received 833,598 calls. This is a 27 percent increase from 2019, when the Helpline received a total of 656,953 calls for the year.

Do I need health insurance to receive this service?

The referral service is free of charge. If you have no insurance or are underinsured, we will refer you to your state office, which is responsible for state-funded treatment programs. In addition, we can often refer you to facilities that charge on a sliding fee scale or accept Medicare or Medicaid. If you have health insurance, you are encouraged to contact your insurer for a list of participating health care providers and facilities.

Will my information be kept confidential?

The service is confidential. We will not ask you for any personal information. We may ask for your zip code or other pertinent geographic information in order to track calls being routed to other offices or to accurately identify the local resources appropriate to your needs.

Do you provide counseling?

No, we do not provide counseling. Trained information specialists answer calls, transfer callers to state services or other appropriate intake centers in their states, and connect them with local assistance and support.

Suggested Resources

  • What Is Substance Abuse Treatment? A Booklet for Families
    Created for family members of people with alcohol abuse or drug abuse problems. Answers questions about substance abuse, its symptoms, different types of treatment, and recovery. Addresses concerns of children of parents with substance use/abuse problems.
  • Alcohol and Drug Addiction Happens in the Best of Families
    Describes how alcohol and drug addiction affect the whole family. Explains how substance abuse treatment works, how family interventions can be a first step to recovery, and how to help children in families affected by alcohol abuse and drug abuse.
  • It’s Not Your Fault (NACoA) (PDF | 12 KB)
    Assures teens with parents who abuse alcohol or drugs that, “It’s not your fault!” and that they are not alone. Encourages teens to seek emotional support from other adults, school counselors, and youth support groups such as Alateen, and provides a resource list.
  • It Feels So Bad: It Doesn’t Have To
    Provides information about alcohol and drug addiction to children whose parents or friends’ parents might have substance abuse problems. Advises kids to take care of themselves by communicating about the problem and joining support groups such as Alateen.
  • After an Attempt: A Guide for Taking Care of Your Family Member After Treatment in the Emergency Department
    Aids family members in coping with the aftermath of a relative’s suicide attempt. Describes the emergency department treatment process, lists questions to ask about follow-up treatment, and describes how to reduce risk and ensure safety at home.
  • Family Therapy Can Help: For People in Recovery From Mental Illness or Addiction
    Explores the role of family therapy in recovery from mental illness or substance abuse. Explains how family therapy sessions are run and who conducts them, describes a typical session, and provides information on its effectiveness in recovery.

For additional resources, please visit the SAMHSA Store.

The Dangers of Mixing Flexeril & Alcohol for Recreational Use

Article at a Glance:

  • Flexeril was a brand name of the muscle relaxant cyclobenzaprine.
  • Though Flexeril is not a controlled substance, it has been used recreationally and can be abused.
  • Since alcohol and Flexeril are both central nervous depressants, mixing them can increase the side effects of each and be deadly.

Recreational Use

Flexeril was a brand name of the skeletal muscle relaxant cyclobenzaprine, which is still sold under the brand names Amrix and Fexmid. Cyclobenzaprine is a prescription medication used to treat muscle spasms and is intended to be used over a short duration of two to three weeks. The drug is not a controlled substance but can nonetheless be abused as a recreational drug to enhance the effects of other central nervous system depressants like alcohol.

When used recreationally, cyclobenzaprine causes relaxation, sedation and, in some cases, a mild euphoric high. It can be taken on its own or combined with other substances like alcohol, barbiturates, benzodiazepines or narcotics. Although rare, deaths from cyclobenzaprine overdose have been reported.

Mixing Alcohol and Flexeril

People may accidentally mix cyclobenzaprine with alcohol when using the medication as prescribed. Conversely, some people intentionally mix Flexeril with other substances to enhance the effects of both substances.

Combining Flexeril with alcohol can be dangerous or even deadly. Both alcohol and Flexeril depress the central nervous system and, when mixed, may enhance each other’s effects. This can result in symptoms like severe sedation or drowsiness and may increase the risk of an accident.

Side Effects & Interactions of Mixing Alcohol and Flexeril

Cyclobenzaprine is known to increase the side effects of drinking and vice versa. This is primarily because both substances are central nervous system depressants. Together, they can impair your mental abilities and coordination and make tasks like driving very hazardous.

Can You Overdose on Flexeril?

Cyclobenzaprine overdose can occur and may be deadly in some cases, especially when combined with other substances like alcohol. Because overdose symptoms can escalate rapidly, it is important to seek emergency medical attention if you think someone has taken too much cyclobenzaprine. The most common signs of a cyclobenzaprine overdose are drowsiness and a fast heartbeat.

Drug overdose can be fatal. If you suspect someone is experiencing an overdose, call 911 immediately. Do NOT be afraid to seek help. If you do not have access to a phone contact Web Poison Control Services for online assistance.

Addiction Risk and Treatment

Although cyclobenzaprine is not a controlled substance, it can still be abused. Further, the drug can cause withdrawal symptoms if a person suddenly stops taking it. If you or a loved one struggles with cyclobenzaprine, treatment is available. Contact our experts at The Recovery Village today to discuss your situation. We can help you start a Flexeril-free life.

  • Sources

    Drug Enforcement Administration. “Cyclobenzaprine.” March 2020. Accessed November 15, 2020.

    Drugs.com. “Cyclobenzaprine.” September 1, 2020. Accessed November 15, 2020.

    Spiller, Henry A.; Cutino, Letizia. “Fatal cyclobenzaprine overdose with postmortem values.” Journal of Forensic Sciences, July 2003. Accessed November 15, 2020.

    Winek Jr, C.L.; Wahba, W.W.; Winek, C.L. “Drowning due to cyclobenzaprine and ethanol.” Forensic Science International, March 15, 1999. Accessed November 15, 2020.

    U.S. National Library of Medicine. “Cyclobenzaprine.” December 30, 2019. Accessed November 15, 2020.

Medical Disclaimer: The Recovery Village aims to improve the quality of life for people struggling with a substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare provider.

Flexeril-Recreational Drug Or A Narcotic With Severe Side Effects?

We live in a world where we almost have a cure for everything. There are a number of drugs for treating one condition. Few of them are strong and few of them can give temporary relief. One of the most common pains in this world is muscle pain and there are ten different drugs that can treat one condition. One of these drugs is Frexeril also called Cyclobenzaprine. It is one of the muscle relaxers that blocks the muscle spasms and pain sensations going to your brain. This relaxant is mostly used with physical therapy to give pain relief from injury, and spasm. It is an inexpensive drug.

Is Flexeril a Narcotic?

No, it is not. It is most commonly used as a muscle relaxer and to low blood pressure but abusing flexeril may cause flexeril addiction. It can be intense and have many adverse effects if it is mixed with any other drug like cocaine, alcohol, etc. It can be snorted and crushed and mixed with alcohol easily to feel a thrill. It is not as widely abused as many other drugs but the potential for abusing is there since it is available at a very low cost.

Among other sorts of substance abuse, abusing Flexeril is also getting common, unfortunately. These effects include nausea, dry mouth, dizziness, laziness, headaches, confusion, etc. It can have a more intense effect since both substances together double the effect. These effects include memory loss, abnormal behavior, difficulty in bleeding, risk of overdose. More so, both drugs have the potential of turning into poison when mixed together. Considering this and many other risk factors, drug addiction treatment centers are now offering  addiction treatment program for Flexeril abuse.

Flexeril as Recreational Drug

Flexeril is a prescription drug that is used to treat skeletal pain, muscle rigidity, back pain, muscle stiffness and high blood pressure caused by minor medical conditions. But many people take it for recreational use. As a recreational drug, it is not recommended for relaxing pain caused by major injuries. More so, many experts are of the view that the substance is not able to provide any psychoactive effect. Since it is not considerd a common drug addiction, many people still try it because of the euphoric Flexeril high it can provide to the brain when an individual is in pain.

But do people abuse Flexeril? Yes, they do! It can be taken orally by swallowing a tablet (which comes in 5 mg or 10 mg) or can be dissolved in water. If you use cyclobenzaprine (Another name for Flexeril), it does have side effects and an addictive sensation. That’s why many people keep on using it after the pain is gone. But in case of Flexeril overdose and the combination with alcohol, intense outcomes are probable.

How Long Does It take For Flexeril To Work

Prescription drugs, like Flexeril is prescribe to help you and Flexeril is faster than many other relaxants in the market. The relaxing effects will start to kick in the first 45 minutes of swallowing the tablet. Many have reported dependency on the drug because of its fast muscle relaxant properties.

However, people who are younger and have a good metabolism system are less likely to suffer from the effects since it leaves their body. It can be a problem for those who are older and or people with above-average body weight. It will harder for them to eliminate the drug from the body.

Side Effects Of Snorting Flexeril

Flexeril, a cheap drug in the market sold as a relaxant can provide euphoric sensations. Therefore, it has a high probability of being abused with other extreme drugs like alcohol and cocaine. NIDA has revealed that people between 18 to 25 abuse Flexeril the most. It causes drug dependence which is the reason why many people use cyclobenzaprine with other drugs to intensify the effect of alcohol, cocaine, etc.

How do you know that Flexeril has become a toxin? When it starts affecting different functions of the body and does not eliminate completely from the body. Some of the most common side effects are slurred speech, difficulty breathing, red eyes, high body temperature, dehydration etc. One of the typical part of the cycle of drug addiction is withdrawal symptoms and Flexeril is no different. When a person leaves Flexeril, it is natural to experience withdrawal symptoms but they can be  treated with medicated assistance around the clock. Whether you’re taking Flexeril for recreational use or you’re abusing Flexeril, you’ll have to sign up for drug rehab to get rid of this addiction. Following are the indicators of when the individual needs this special assistance around the clock.

Flexeril Causes Anxiety

Severe central nervous system problems can be caused by Flexeril followed by other mental issues like confusion, abnormal behavior, etc. One of the most common situations the regular users have to go through is the anxiety which later changes into dizziness and drowsiness sucking up all the energy. Why does it affect the human brain like that? It has antihistamines that can play with your emotions and cause dizziness and drowsiness at the same time.

Flexeril Causes Depression

Since it has a relaxing effect, it is considered as one of the drugs which can cause an individual to depend on them. It has also been reported that an higher doses of Flexeril can cause severe health problems and one of them is depression. This depression is a major one which might need special medical assistance in the future. However, the good news is that many people do not go to an extent where Flexeril causes central nervous depression.

Flexeril Can Affect Your Heart

Flexeril is not a harmful prescription but it does have severe health effects if it is continually used for longer periods. Flexeril overdose can cause serious heart and liver damage. While cardiac arrest and heart attack are less common side effects, they are not impossible to happen. Felxeril overdose may cause chest pain and increased heart rate which is life threatening.

Flexeril Treatment

Flexeril addiction treatment follows the same pattern of any other medicine. An important thing is that it is used with other drugs and proper physical therapy under the supervision of a doctor. Since, abusing prescription medication is sadly getting common now, there are many treatment options now. A good addiction treatment center will take Flexeril addiction as much seriously as any other drug addiction.

When you undergo addiction treatment and withdraw from flexeril, you might experience constant dry mouth which is one of the most common withdrawal symptoms of flexeril. Sometimes, the withdrawal effects may look overwhelming and one might relapse but seeking addiction treatment, no matter how insignificant you think your drug addiction is, is important since it can get you in serious trouble in the long run. Many addiction recovery centers offer prescription drug abuse treatment programs so if you are involved in flexeril abuse or you know someone who is, it’s about time to get help.

Flexeril Tablet

If it is prescribed to you, take the tablet. Do not crush and snort it in otherwise the tablet is going to have adverse effects. When you take the tablet, make sure to eat before it. An empty stomach is never good for almost any medical treatment. In case your pain is unbearable, do not increase the dosage on your own. Do not take the dosage longer than the prescribed time.

Another important thing which you need to keep in mind even if the doctor does not inform you is that it is a short term medication and cannot be taken for more than 3 weeks since it has addictive properties which can have massive side effects. Flexeril is a useful drug. However, too much of it can cause real problems for your health. Make sure to consult a doctor before taking Flexeril. It can give you relief but when used in excess, it can cause trouble.


How much does the Flexeril cost?

It is a cheap medication that can be purchased from any drugstore. However, it has to be prescribed by a physician.

How long should it be taken?

It should be taken for three weeks maximum since it is a short term drug.

Can it be used as a relaxant for other health treatments?

No, so far it is only recommended as a muscle relaxant and for muscle spasms.

What can an overdose of Flexeril do?

Since the medication has the ability to get an individual high, it can get you addicted.

How does Flexeril high makes you feel?

Flexeril high acts as a muscle relaxer and makes you feel light.

Therapeutic Use And Risk Of Addiction

Cyclobenzaprine, marketed with the brand name Flexeril, belongs to a drug class of central nervous system acting muscle relaxants. Cyclobenzaprine or Flexeril drug class is promoted primarily for prescription, short-term treatment of muscle spasms caused by acute, painful musculoskeletal ailments. Since its appearance on the pharmaceutical market in 1977, Flexeril use has increased, becoming one of the most frequently prescribed medications. This article concentrates on the categorization of cyclobenzaprine, its mechanism of action in relief of muscle spasms, which demographic uses Flexeril medication the most, and the risks and treatment options for cyclobenzaprine addiction.

Recent research shows that prescription myorelaxant use, including the Flexeril pill, has doubled between 2005-2018. Hence, Cyclobenzaprine abuse and addiction bear a severe danger, especially for those who use this substance with higher dosages or for more extended periods than intended.

What is Cyclobenzaprine?

Cyclobenzaprine (Flexeril) is a centrally acting muscle or myorelaxant. It is indicated as a short-term (2-3 week) adjunct treatment in addition to physical or occupational therapy for the relief of acute muscle spasms caused by local tissue trauma or sprains and strains.

Pharmacodynamics or the mechanism of its action is not fully clear, but it appears to act on supraspinal noradrenergic and serotonergic neurons, specifically at the level of locus coeruleus in the rostral pons of the brain stem. Through its actions, it inhibits efferent neuronal output to the spinal cord, depressing muscular conduction and thus preventing muscle spasm and the associated pain. Cyclobenzaprine, ordinarily prescribed as a Flexeril pill, is frequently used for the treatment of symptoms associated with lower back pain. Off-label use of Flexeril medication includes treatment of neuropathic pain of fibromyalgia, chronic non-cancer pain, temporomandibular disorder pain, and various other non-pain conditions. However, the Flexeril pill appears to be ineffectual in the treatment of muscle spasticity that results from spinal cord disease or pediatric cerebral palsy.

Cyclobenzaprine Brand And Generic Names

There are over 400 pharmaceutical companies that manufacture generic forms and over 15 companies that produce brand-name Cyclobenzaprine. Given below are some common generic and brand names:

  • Cyclobenzaprine hydrochloride
  • Flexeril
  • Amrix
  • Fexmid
  • Mylan-Cyclobenzaprine
  • Comfort Pac with Cyclobenzaprine
  • Apo-Cyclobenzaprine
  • Novo-Cycloprine
  • Jamp-cyclobenzaprine
  • Dom-cyclobenzaprine

Cyclobenzaprine is also available as a mixture of products used for stronger pain relief:

  • Cyclo/Gaba 10/300 Pack containing Gabapentin
  • NOpiod-TC containing Levomenthol, and Lidocaine

Flexeril Dosage Forms And Strengths

Cyclobenzaprine is offered in doses of 5 mg, 10 mg, 15 mg, and 30 mg, as well as in various formulations:

  • Oral tablet
  • Oral, film-coated tablet
  • Oral extended-release capsule

Flexeril pill is five-sided and has two colors, depending on the dosage:

  • The 10 mg pill is yellow in color. “Flexeril MSD 931” is engraved on it. It is contained in a white bottle with some yellow tints.
  • The  5 mg pill is orange in color. The pill imprint is just “Flexeril.” It is also contained in a while bottle, with the brand name printed in blue.

Capsule forms of Flexeril are also available.

  • The 30mg capsule of extended-release oral form is half blue and half red, with white text on the capsule.
  • The 15mg capsule of extended-release oral form is orange, also with white text on the capsule.

Regardless it is currently not a controlled substance under The Controlled Substances Act (CSA), but it remains a prescription medication due to its excessive frequency of Cyclobenzaprine abuse and addiction.

Flexeril Drug Class

Cyclobenzaprine (Flexeril) is akin to a class of drugs, known as cyclical antidepressants. Cyclical antidepressants have been employed for the treatment of a wide array of conditions ranging from major depressive disorder(MDD), neuropathic pain, migraine, and attention deficit hyperactive (ADHD).

The most commonly known agents from Flexeril drug class are Tricyclic Antidepressants (TCAs). TCAs have been used to treat psychosis, mood disorders, and neuropathic pain. However, these drugs have wide adverse side effect profiles, a high likelihood for lethality and are, thus, prescribed cautiously. Cyclobenzaprine side effects, being part of this class of cyclical antidepressants, is no exception.

Indication For Flexeril Use And Risk of Addiction

Cyclobenzaprine is frequently prescribed to patients as part of a treatment regimen for acute musculoskeletal pain. The duration of its use is only for a brief period of time, usually a maximum of two to three weeks. The reasoning behind this rests upon studies that demonstrate that beyond two to three weeks, its use has no proven benefit. Thus, therapy should not be continued past this time frame. Furthermore, muscle relaxants like Flexeril are often prescribed along with opioids which increase the possibility of Cyclobenzaprine interactions, side effects and may even increase the likelihood of cyclobenzaprine addiction.

The risk of cyclobenzaprine addiction or dependence is quite low, and as such, it is not considered a Controlled Substance under the CSA. However, patients often acquire this medication without a prescription and continue to take it beyond the duration of prescribed treatment. These acts can be defined as Cyclobenzaprine abuse. According to the Drug Enforcement Administration, an 87% increase was observed from the years 2004 to 2011 in the number of Emergency room visits because of Flexeril medication abuse.

The Reasoning Why Flexeril Misuse Is So Frequent Can Possibly Be Attributed to Various Factors:

  • Flexeril has a short window of effectiveness for the management of pain symptoms, and patients often develop a tolerance to its effects. With tolerance, the pain returns, and patients are often prompted to take increasingly higher doses of Flexeril to attain the desired effect.
  • Flexeril medication is not a controlled substance and only requires a prescription. Patients often view prescription drugs as safer than illicit drugs. This makes prescription drugs, like the Flexeril pill, targets for abuse according to the National Institute on Drug Abuse (NIDA).
  • Since Flexeril is a central nervous system acting substance related to Tricyclic Antidepressants, it is capable of producing sedation, anxiolysis, and hypnosis. These aforementioned effects can be heightened if Flexeril is combined with other CNS acting agents, such as benzodiazepines, barbiturates, opioids and alcohol. The combined effect of these agents together makes cyclobenzaprine abuse more likely to happen.
  • Cyclobenzaprine can also produce hypnosis, anxiolysis, and feelings of euphoria. These effects increase the risk of potential recreational cyclobenzaprine abuse, especially by adolescents.

Who Is Most at Risk Of Cyclobenzaprine Addiction?

Similar to other substance use disorders, Cyclobenzaprine abuse alone or in combination with other substances can be predisposed to by the following risk factors:

  • Family history of addiction and substance abuse
  • Personal history of addiction and substance abuse
  • Imitation of peers and peer pressure
  • Coping with tensions or problems in the family such as neglect, marital discord, and job loss
  • Coping with stigmatization in school or community
  • As a form of acting out in adolescents
  • Regular exposure to a social environment where substance abuse is accepted

According to the National Survey on Drug Use and Health(SAMHSA), around 25 million people ages 12 and up have abused prescription drugs like Flexeril. However, adolescents between the ages of 18 to 25 who obtain the drug from peers, relatives or buy it online comprise the most significant percentage of patients with cyclobenzaprine abuse problems. The alternative demographic of patients potentially at risk of cyclobenzaprine addiction and abuse includes older patients over 50 years of age. These patients often have authorized prescriptions for Flexeril medication for the management of acute musculoskeletal pain, but soon develop tolerance and subsequently take increasingly higher or more frequent doses or they continue to take the drug for a prolonged course as mentioned previously.

Cyclobenzaprine Abuse Statistics

Cyclobenzaprine, according to the Drug Enforcement Administration(DEA), has been available in the United States since 1977 and remains one of the most frequently prescribed substances. In 2011 over 25 million prescriptions were given out for Cyclobenzaprine, making it one of the most commonly prescribed medications for the management of musculoskeletal pain, in particular back pain.

Furthermore, in 2018 the Medical Expenditure Panel Survey (MEPS) reported that it was 43rd among the list of most frequently prescribed medications. In accordance with yet another report, an estimated 5.2 million people used this medication, with over 256,000 people having abused it at least once.

Signs and Symptoms Of Cyclobenzaprine Abuse And Addiction

Common signs and symptoms of Cyclobenzaprine addiction and abuse are nearly indistinguishable from other substance use disorders. They can be suspected when a maladaptive pattern of its use leads to clinically significant impairment or distress, as manifested by the following psychosocial, behavioral, and/or physical signs.

Psychosocial and Behavioral Signs

Patients who are addicted to Cyclobenzaprine and abuse it, manifest a set of recognizable signs and symptoms. Even though these signs and symptoms are not specific to only Flexeril addiction and/or abuse, their presence should raise suspicion and necessitate the need to ask questions and voice concerns.

  • Cyclobenzaprine abuse harms the fulfillment of obligations at work, school, or home.
  • Patients continue its use despite social or interpersonal problems caused or exacerbated by its effects.
  • Patients lie or become anxious when their use of Flexeril is questioned.
  • Important social, occupational, or recreational activities are given up or reduced by patients because of Cyclobenzaprine abuse.
  • Patients either use Flexeril in more substantial amounts or for a more extended period than intended.
  • Patients often have a  persistent desire or unsuccessful efforts to cut down or control their use.
  • Patients spend a great deal of time on activities necessary to obtain, use, or to recover from its effects.
  • Patients have a craving or a strong desire to use Flexeril.
  • Patients continue the use of Flexeril despite its adverse effects.
  • Patients may steal or forge prescriptions to obtain Flexeril.
  • A phenomenon of “Doctor Shopping” or visiting multiple doctors to obtain multiple prescriptions can be seen in patients with Cyclobenzaprine abuse or addiction.
  • Patients often use Flexeril in situations in which it is physi­cally hazardous to themselves, sometimes referred to as “risky use”.
  • Patients continue the drug use despite physical or psychologi­cal problems caused by its use.
  • Patients develop tolerance, exemplified by a need for markedly increased doses to attain the desired effects or by a markedly diminished effect with continued use of the same dose.
  • Patients develop withdrawal, exemplified by the appearance of a substance-specific collection of symptoms following abrupt cessation or decreased Flexeril consumption.

Physical Signs

Physical signs of abuse or addiction reveal when the patient consumes increased dosages of the drug. These signs can include:

  • Autonomic nervous system instability manifested by tremors, agitation, dizziness, vomiting, and increased heart rate.
  • Slurred speech
  • Mood swings
  • Changes in sleeping patterns or habits
  • Unexplained weight gain or loss
  • Inability to think well
  • Untidy appearance

Possible Dangers of Cyclobenzaprine Abuse

Cyclobenzaprine is safe for consumption as per the Food and Drug Association(FDA)  when used as directed by a physician and for the appropriate duration. However, this drug can have serious and even life-threatening side effects if abused or used incorrectly.

Hypersensitivity or Allergy

Hypersensitivity or allergic reactions such as rash, urticaria, and even life-threatening anaphylaxis can occur in a subset of patients. In the elderly, especially when combined with other CSN acting agents like opioids, it can cause severe drowsiness and increases the risk of falls.


The most severe consequence is overdose, which can frequently occur with abuse or when used in patients who have poor hepatic or renal health. Symptoms and signs of overdose are associated primarily with its anticholinergic properties, such as autonomic instability and CNS depression, linked to it being similar to Tricyclic Antidepressants. Furthermore, since this class of drug has a centrally acting inhibitory action, it should not be combined with other CNS depressant drugs, such as alcohol or benzodiazepines, as they have additive functions and can result in life-threatening cardiovascular or respiratory compromise. Learn more, how long does Flexeril stay in your system.


Abrupt cessation or decreasing the dose taken in those patients who have been abusing this drug for a prolonged period of time is also dangerous, as this can provoke symptoms and signs of acute withdrawal such as progressively worsening flu-like symptoms.

Cyclobenzaprine Abuse Treatment Options

Acute management of overdose or severe withdrawal is complex and requires immediate contact of emergency medical services and the poison control center for immediate help. Typical management of acute overdose or withdrawal involves gastrointestinal decontamination, close cardiac monitoring, and monitoring for signs of central nervous system or respiratory depression.

Cyclobenzaprine addiction and abuse treatment are twofold. A three-month rehabilitation course offers a pathway to overcoming one’s addiction. A rehabilitation course provides two services.

  • The first step is medically supervised “detox”, during which patients go through their withdrawal symptoms in a safe, comfortable, and controlled environment. This ensures that if any possible complications to the patient’s health arise, they can be promptly managed and alleviated with pharmaceuticals’ aid to promote rapid recovery.
  • The second step involves various types of counseling, which encompass individual and group therapy, cognitive behavioral therapy, family therapy, life skill development, 12-step program, education concerning addiction and dependence, as well as development and implementation of relapse prevention strategies.

Patients can choose from:

  • Residential Inpatient Drug Rehab programs offer live-in facilities that provide secure and drug-free residence settings and medical facilities within one location. Patients adhere to a day-to-day controlled schedule that encompasses various steps of counseling. This kind of program is indicated for people with intense addiction or those who have previously relapsed.
  • Outpatient Drug Rehab programs are applicable to patients with no past medical history of substance use disorder. Participants in these programs meet several times during the week, and the program allows patients to have flexible schedules that permit time for school, work, or caring for one’s family.

Regardless of the kind of program chosen, after successfully completing therapy for Flexeril abuse and addiction, aftercare is necessary. Aftercare programs offer ongoing support for recovering addicts through regularly scheduled group sessions. During these sessions, patients can share their stories of trials, tribulations, and success on the road to recovery from Flexeril addiction in a safe and non-judgmental environment. Furthermore, patients can hear about recovery stories of other previous addicts as they work toward their goal of sustained and prolonged sobriety.

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Page Sources

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  2. Summary of Misuse of Prescription Drugs. (2021, February 2). National Institute on Drug Abuse. https://www.drugabuse.gov/publications/research-reports/misuse-prescription-drugs/overview
  3. United States Food and Drug Association. (n.d.). FLEXERIL (CYCLOBENZAPRINE HCl) Tablets. Https://Www.Accessdata.Fda.Gov. Retrieved March 2021, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2003/017821s045lbl.pdf
  4. Substance Abuse and Mental Health Services Administration, Drug Abuse Warning Network, 2011: National Estimates of Drug-Related Emergency Department Visits. HHS Publication No. (SMA) 13-4760, DAWN Series D-39. Rockville, MD: Substance Abuse and Mental Health Services Administration, 2013
  5. U.S. Department of Justice Drug Enforcement Administration Diversion Control Division. (2020, March). CYCLOBENZAPRINE (Brand Name: Flexeril®, Amrix®). Deadiversion.Usdoj.Gov. https://www.deadiversion.usdoj.gov/drug_chem_info/cyclobenzaprine.pdf
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  7. Cyclobenzaprine | DrugBank Online. (n.d.). DrugBank. Retrieved March 2021, from https://go.drugbank.com/drugs/DB00924
    Cyclobenzaprine. (2020, December). Drugs.Com. https://www.drugs.com/cyclobenzaprine.html
  8. Katzung, B., & Trevor, A. (2020). Basic and Clinical Pharmacology 15e (15th ed.). McGraw-Hill Education / Medical
  9. Soprano SE, Hennessy S, Bilker WB, Leonard CE. Assessment of Physician Prescribing of Muscle Relaxants in the United States, 2005-2016. JAMA Netw Open. 2020;3(6):e207664. doi:10.1001/jamanetworkopen

Published on: November 30th, 2018

Updated on: March 26th, 2021

After successful graduation from Boston University, MA, Sharon gained a Master’s degree in Public Health. Since then, Sharon devoted herself entirely to the medical niche. Sharon Levy is also a certified addiction recovery coach.

8 years of nursing experience in wide variety of behavioral and addition settings that include adult inpatient and outpatient mental health services with substance use disorders, and geriatric long-term care and hospice care.  He has a particular interest in psychopharmacology, nutritional psychiatry, and alternative treatment options involving particular vitamins, dietary supplements, and administering auricular acupuncture.

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Snorting Flexeril | Cyclobenzaprine Insufflation

Flexeril is a prescription muscle relaxant that helps manage short-term muscle spasms and back pain. People that snort Flexeril may experience uncomfortable negative side effects, including possible heart attack.

Cyclobenzaprine, known by the brand names Flexeril or Amrix, is a prescription muscle relaxer that is used to help with muscle pain and spasms, alongside a regimen of physical therapy.

It acts as a central nervous system depressant and is typically prescribed on a short-term or as-needed basis, as a therapeutic and not for managing chronic pain.

While Flexeril does not create the same feelings of euphoria that benzodiazepines or opioids do when taken in higher doses, Flexeril does make people feel drowsy and will slow down vital functions.

Snorting Flexeril Drug Abuse

People that abuse Flexeril may crush and dilute pills in water for faster oral intake, or they may crush and snort pills to feel a faster high.

Because Flexeril doesn’t produce a traditionally sought after “high”, it has not been shown that snorting Flexeril is an effective way to take this drug.

The act of crushing and snorting any prescription medication may be a sign of an emerging or existing substance abuse issue that should be addressed.

Side Effects Of Abusing Flexeril

When Flexeril is used according to medical advice, it can improve energy levels, motor function, sleep, and quality of life for people with skeletal muscle pain and spasms.

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