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Does mobic contain aspirin: Common Medications Containing Aspirin, Other Nonsteroidal Anti-inflammatory Drugs (NSAIDs), or Vitamin E

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Common Medications Containing Aspirin, Other Nonsteroidal Anti-inflammatory Drugs (NSAIDs), or Vitamin E

This information will help you identify medications that contain aspirin, other NSAIDs, or vitamin E. It’s important to stop taking these medications before many cancer treatments. They affect your platelets (blood cells that clot to prevent bleeding) and can increase your risk of bleeding during treatment.

Other dietary supplements (such as other vitamins and herbal remedies) can also affect your cancer treatment. For more information, read the resource Herbal Remedies and Cancer Treatment.

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Instructions Before Your Cancer Treatment

If you take aspirin, other NSAIDs, or vitamin E, tell your healthcare provider. They’ll tell you if you need to stop taking it. You’ll also find instructions in the information about your treatment. Read the “Examples of Medications” section to see if your medications contain aspirin, other NSAIDs, or vitamin E.

Before your surgery

Follow these instructions if you’re having surgery or a surgical procedure. If your healthcare provider gives you other instructions, follow those instead.

  • If you take aspirin or a medication that contains aspirin, you may need to change your dose or stop taking it 7 days before your surgery. Follow your healthcare provider’s instructions. Don’t stop taking aspirin unless your healthcare provider tells you to.
  • If you take vitamin E or a supplement that contains vitamin E, stop taking it 7 days before your surgery or as directed by your healthcare provider.
  • If you take an NSAID or a medication that contains an NSAID, stop taking it 48 hours (2 days) before your surgery or as directed by your healthcare provider.

Before your radiology procedure

Follow these instructions if you’re having a radiology procedure (including Interventional Radiology, Interventional Mammography, Breast Imaging, and General Radiology). If your healthcare provider gives you other instructions, follow those instead.

  • If you take aspirin or a medication that contains aspirin, you may need to stop taking it 5 days before your procedure. Follow your healthcare provider’s instructions. Don’t stop taking aspirin unless your healthcare provider tells you to.
  • If you take an NSAID or a medication that contains an NSAID, you may need to stop taking it 24 hours (1 day) before your procedure. Follow your healthcare provider’s instructions.

Before and during your chemotherapy

Chemotherapy can lower your platelet count, which can increase your risk of bleeding. Whether you’re just starting chemotherapy or have been getting it, talk with your healthcare provider before taking aspirin, other NSAIDs, or vitamin E.

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Examples of Medications

Medications are often called by their brand name. This can make it hard to know their ingredients. The lists below can help you identify medications that contain aspirin, other NSAIDs, or vitamin E.

These lists include the most common products, but there are others. Make sure your healthcare provider always knows all the prescription and over-the-counter (not prescription) medications you’re taking, including patches and creams.

Common Medications Containing Aspirin
Aggrenox®Cama® Arthritis Pain RelieverHeartline®Robaxisal® Tablets
Alka Seltzer®COPE®Headrin®Roxiprin®
Anacin®Dasin®Isollyl®Saleto®
Arthritis Pain FormulaEasprin®Lanorinal®Salocol®
Arthritis Foundation Pain Reliever®Ecotrin® (most formulations)Lortab® ASA TabletsSodol®
ASA Enseals®Empirin® Aspirin (most formulations)Magnaprin®Soma® Compound Tablets
ASA Suppositories®Epromate®Marnal®Soma® Compound with Codeine Tablets
Ascriptin® and Ascriptin A/D®Equagesic TabletsMicrainin®St. Joseph® Adult Chewable Aspirin
Aspergum®Equazine®Momentum®Supac®
Asprimox®Excedrin® Extra-Strength Analgesic Tablets and CapletsNorgesic Forte® (most formulations)Synalgos®-DC Capsules
Axotal®Excedrin® MigraineNorwich® AspirinTenol-Plus®
Azdone®Fiorgen®PAC® Analgesic TabletsTrigesic®
Bayer® (most formulations)Fiorinal® (most formulations)Orphengesic®Talwin® Compound
BC® Powder and Cold formulationsFiortal®Painaid®Vanquish® Analgesic Caplets
Bufferin® (most formulations)Gelpirin®Panasal®Wesprin® Buffered
Buffets II®Genprin®Percodan® TabletsZee-Seltzer®
Buffex®Gensan®Persistin®ZORprin®
Common NSAID Medications That Don’t Contain Aspirin
Advil®Duexis®Mefenamic AcidPediaCare Fever®
Advil Migraine®Etodolac®MeloxicamPiroxicam
Aleve®Feldene®Menadol®Ponstel®
Anaprox DS®FenoprofenMidol®Relafen®
Ansaid®FlurbiprofenMobic®Saleto 200®
Arthrotec®Genpril®Motrin®Sulindac
Bayer® Select Pain Relief Formula CapletsIbuprofenNabumetoneToradol®
Celebrex®IndomethacinNalfon®Treximet®
CelecoxibIndocin®NaproxenVicoprofen®
Children’s Motrin®KetoprofenNaprosyn®Vimovo®
Clinoril®KetorolacNuprin®Voltaren®
Daypro®Lodine®Orudis® 
DiclofenacMeclofenamateOxaprozin 
Products Containing Vitamin E
Amino-Opt-EAquavitE-400 IUE complex-600
Aquasol ED’alpha EE-1000 IU SoftgelsVita-Plus E

Most multivitamins contain vitamin E. If you take a multivitamin, check the label.

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About Acetaminophen

Acetaminophen (Tylenol®) is generally safe to take during your cancer treatment. It doesn’t affect platelets, so it won’t increase your chance of bleeding. But, talk with your healthcare provider before taking acetaminophen if you’re getting chemotherapy.

 

Medications Containing Acetaminophen
Acephen®Esgic®Percocet®Vanquish®
Aceta® with CodeineExcedrin P.M.®Primlev®Vicodin®
Acetaminophen with CodeineFiorcet®Repan®Wygesic®
Aspirin-Free Anacin®Lorcet®Roxicet®Xartemis XR®
Arthritis Pain Formula® Aspirin-FreeLortab®Talacen®Xodol®
Datril®Naldegesic®Tempra®Zydone®
Di-Gesic®Norco®Tylenol® 
Endocet®Panadol®Tylenol® with Codeine No. 3 

Read the labels on all your medications

Acetaminophen is safe when used as directed. But there’s a limit to how much you can take in a day. It’s possible to take too much without knowing because it’s in many different prescription and over-the-counter medications. It’s often an ingredient in pain relievers, fever reducers, sleep aids, and cough, cold, and allergy medications.

The full name acetaminophen isn’t always written out. Look for the common abbreviations listed below, especially on prescription pain relievers.

Common Abbreviations for Acetaminophen
APAPACAcetaminop
AcetaminAcetamAcetaminoph

Always read and follow the label on the product you’re taking. Don’t take more than 1 medication that contains acetaminophen at a time without talking with a member of your healthcare team.

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Safety of meloxicam in aspirin-hypersensitive patients with asthma and/or nasal polyps. A challenge-proven study


Background:

The anti-inflammatory actions of acetylsalicylic acid (ASA)/non-steroidal anti-inflammatory drugs (NSAIDs) are thought to be due to inhibition of COX-2, whereas the side effects such as gastric damage and aspirin-induced asthma are mediated through inhibition of COX-1. Therefore, a new class of drugs with COX-2 selectivity may be well tolerated by patients with ASA/NSAIDs hypersensitivity.


Objective:

We investigated whether subjects with asthma and/or nasal polyps (NP) and analgesic intolerance proven by oral ASA provocation test tolerated the selective COX-2 inhibitor, meloxicam.


Methods:

All subjects were first challenged with ASA using a 2-day, single-blind, placebo-controlled oral provocation test. Thereafter, the subjects showing positive response to ASA provocation underwent a single-blind, placebo-controlled challenge with a cumulative dose of 7.5 mg of meloxicam on 2 separate days. One and three fourths of the divided doses of placebo and the active drug were given at 1-hour intervals. Clinical symptoms, lung function, and blood pressure were monitored during these challenge protocols.


Results:

Twenty-one patients with asthma and/or NP (10 males and 11 females; mean age: 38.4 +/- 2.9 years) who reacted to ASA challenges were enrolled in the study. Response to ASA provocation was rhinitis + bronchospasm in 13, and extrabronchial reactions in 8 (isolated rhinitis in 3) patients. Mean PD(20) was 163.4 +/- 39.9 mg ASA among patients who reacted with bronchospasm to ASA. Only 1 patient reacted to meloxicam challenge at a cumulative dose of 7.5 mg.


Conclusion:

This study indicates that 7. 5 mg of meloxicam is a safe alternative treatment for ASA-hypersensitive asthma and/or NP patients with proven hypersensitivity via oral ASA challenges.

Acetaminophen vs. NSAIDs during COVID-19 pandemic

Many people are asking doctors for information about whether it is safe to use NSAID drugs now.  Examples of this drug class include ibuprofen (generic, Advil, Motrin), naproxen (generic, Aleve), diclofenac (generic, Voltaren, Arthrotec), celecoxib (Celebrex), meloxicam (Mobicox) and many others.

Feeling an increase in your body temperature can tell you if you are sick.  And, fever is an important vital sign which can alert doctors and nurses about your clinical condition.  However, it is not usually medically necessary to suppress fever.

The science is unsettled about the relationship between COVID-19 and NSAIDs and there are contradictory viewpoints because we lack high quality evidence on which to base recommendations.

Please check our list of links for emerging evidence and clinical recommendations for COVID-19.

We offer this common sense review about treating pain and fever for viral infections:

  1. Relieving fever and treating pain are comfort measures that can help people stay active and/or maintain good eating and sleeping patterns, but are NOT needed to shorten the duration of illness.
  2. Acetaminophen (generic and Tylenol, also the same as paracetamol and Panadol, etc.) can help some types of pain and can lower the temperature in fever. Follow package instructions and do not use more than 3,000 mg per day.

Advantages of acetaminophen: 

    • It does not cause bleeding, is not known to harm the heart or increase blood pressure, and is rarely harmful to the kidney.
    • It can be used cautiously even in liver disease except for liver failure.

Therefore acetaminophen has been regarded for decades as the safest drug to use for pain or fever.   Some over-the-counter medicines contain acetaminophen.  Be careful not to consumer more than 3000 mg per day.

  1. NSAID (non-steroidal anti-inflammatory drugs including ASA/aspirin) are sometimes helpful or prescribed for acute inflammation (e.g. acute gout or arthritis). While many people use NSAIDs for chronic arthritis or muscular pain or headache, it is less clear whether they work any better than placebo. They can be stopped safely if you prefer not to use them.  These drugs can also lower fever.
  2. Disadvantages of NSAIDs (other than low-dose ASA/aspirin): All NSAIDs, and ASA/aspirin, have the potential to cause ulcers and bleeding from the stomach or duodenum. This can sometimes be very serious or even fatal.  In people with impaired kidney function or heart disease, NSAIDs can worsen both.  They may also have a small effect of increasing heart attacks.  Therefore they should always be used with caution.
  3. ASA/aspirin is different. It can prevent strokes and heart attacks, and at the low doses used for this purpose (81-325mg/d), it does not harm the kidneys or heart function. If you have been prescribed ASA/aspirin, do not stop taking it without asking your doctor.
  4. Is it dangerous to take NSAIDs now? There has been speculation and conflicting information in the media that NSAIDS (not low dose ASA/aspirin) could worsen lung problems from viral pneumonia, including Covid-19. This question cannot be answered because we currently lack high quality evidence.  See our list of links if you have a professional interest.

Summary: 

  • Acetaminophen (if available) is the best choice for fever or minor pain.
  • Use NSAIDs only if the advantages for pain truly outweigh the potential disadvantages.
  • Remember that it is rarely necessary to lower your temperature.
  • Fever is one of the key vital signs that allow nurses and doctors to recognize whether a sick patient is improving or worsening. If you are sick and need to seek advice or treatment, measure your temperature (if you have a thermometer), and your heart rate, and be prepared to report them accurately.

NSAIDs – NHS

Non-steroidal anti-inflammatory drugs (NSAIDs) are medicines that are widely used to relieve pain, reduce inflammation, and bring down a high temperature.

They’re often used to relieve symptoms of headaches, painful periods, sprains and strains, colds and flu, arthritis, and other causes of long-term pain.

Although NSAIDs are commonly used, they’re not suitable for everyone and can sometimes cause troublesome side effects.

This information is a general overview of NSAIDs.

For information about a specific medicine, you can look up your medicine on our Medicines A-Z.

Coronavirus advice

There have been some news reports of anti-inflammatory painkillers, such as ibuprofen, making coronavirus worse.

The Commission on Human Medicines has now confirmed there is no clear evidence that using ibuprofen to treat symptoms such as a high temperature makes coronavirus worse.

You can take paracetamol or ibuprofen to treat symptoms of coronavirus. Try paracetamol first if you can, as it has fewer side effects than ibuprofen and is the safer choice for most people.

Always follow the instructions that come with your medicine.

Types of NSAIDs

NSAIDs are available as tablets, capsules, suppositories (capsules inserted into the bottom), creams, gels and injections.

Some can be bought over the counter from pharmacies, while others need a prescription.

The main types of NSAIDs include:

NSAIDs may be sold or prescribed under these names or a brand name.

They’re all similarly effective, although you may find a particular one works best for you.

Who can take NSAIDs?

Most people can take NSAIDs, but some people need to be careful about taking them.

It’s a good idea to ask a pharmacist or doctor for advice before taking an NSAID if you:

  • are over 65 years of age
  • are pregnant or trying for a baby
  • are breastfeeding
  • have asthma
  • have had an allergic reaction to NSAIDs in the past
  • have had stomach ulcers in the past
  • have any problems with your heart, liver, kidneys, blood pressure, circulation or bowels
  • are taking other medicines
  • are looking for medicine for a child under 16 (do not give any medicine that contains aspirin to children under 16)

NSAIDs might not necessarily need to be avoided in these cases, but they should only be used on the advice of a healthcare professional as there may be a higher risk of side effects.

If NSAIDs are not suitable, your pharmacist or doctor may suggest alternatives to NSAIDs, such as paracetamol.

Side effects of NSAIDs

Like all medicines, there’s a risk of side effects from NSAIDs.

These tend to be more common if you’re taking high doses for a long time, or you’re elderly or in poor general health.

Over-the-counter NSAIDs generally have fewer side effects than stronger prescription medicines.

Possible side effects of NSAIDs include:

If you get any troublesome side effects, stop taking your medicine and tell your doctor.

Interactions with other medicines

Some NSAIDs can react unpredictably with other medicines.

This can affect how well either medicine works and increase the risk of side effects.

It’s particularly important to get medical advice before taking an NSAID if you’re already taking:

If you’re not sure whether a medicine you’re taking is safe to take at the same time as an NSAID, check the leaflet that comes with it, or ask a pharmacist or doctor for advice.

Food and alcohol

The leaflet that comes with your medicine should say whether you need to avoid any particular foods or drinks. Ask your pharmacist or doctor if you’re not sure.

For information about a specific medicine, check the A-Z of medicine leaflets on the GOV.UK website.

Generally, you do not need to avoid any specific foods while taking NSAIDs. 

Tablets or capsules should normally be swallowed whole and without chewing with water or food to stop them upsetting your stomach.

It’s usually safe to drink alcohol while taking NSAIDs, but drinking alcohol excessively may irritate your stomach.

Overdoses of NSAIDs

Taking too much of an NSAID can be dangerous. This is known as taking an overdose.

Contact your GP or NHS 111 for advice immediately if you take too much of your medicine and you experience problems such as feeling or being sick, an upset stomach or drowsiness.

Call 999 for an ambulance immediately if you or someone else experiences serious effects of an overdose, such as fits (seizures), breathing difficulties, or loss of consciousness.

Alternatives to NSAIDs

As NSAIDs can cause troublesome side effects, alternatives are often recommended first.

The main alternative for pain relief is paracetamol, which is available over the counter and is safe for most people to take.

NSAID creams and gels that you rub into your skin may be worth trying first if you have muscle or joint pain in a particular part of your body, as they tend to have fewer side effects than tablets or capsules.

Your doctor may also be able to recommend different medicines and therapies depending on the health problem you have.

For example, physiotherapy may help some people with muscle or joint pain.

Page last reviewed: 27 February 2019
Next review due: 27 February 2022

NSAIDs

NSAIDs (nonsteroidal anti-inflammatory drugs) are some of the most commonly used pain medicines in adults. They are also a common treatment for chronic (long-term) health problems, such as arthritis (rheumatoid arthritis, osteoarthritis, and others) and lupus. NSAIDs block proteins, called enzymes, in the body that help make prostaglandins. Prostaglandins are a group of naturally occurring fatty acids that play a role in pain and inflammation. NSAIDs also can decrease inflammation, such as fever, swelling, and redness.

Traditional NSAIDs include aspirin, ibuprofen (Advil, Motrin, etc. ), naproxen (e.g., Aleve), and many other generic and brand name drugs. Celecoxib (Celebrex) belongs to a newer class of NSAIDs, which doctors call a “COX-2 inhibitor,” and is designed to avoid upset stomach.

How to Take It

Each NSAID has its own dose (strength) and interval for how often to take the drug. The dosage size of over-the-counter medicine (those sold without a doctor’s prescription) is often less than prescription versions of the same medicine. NSAIDs start to work quickly, most often within a few hours. How fast they take affect depends on the intended effect. Pain control tends to occur much quicker than anti-inflammatory effects, such as improvement of swelling.

Do not mix an over-the-counter NSAID with a prescribed NSAID or take more than the recommended dose of the NSAID. Doing so could increase your chance of side effects. Doctors have long warned not to give aspirin to children under age 12, but teens with a virus also should avoid drugs containing aspirin. There is a risk of Reye’s syndrome, a rare but deadly illness that can affect the brain and liver.

Side Effects

All drugs have a risk of side effects, including NSAIDs. It is important to understand the risks and benefits of a drug before deciding to take it. Possible risks of all NSAIDs include: stomach problems (such as bleeding, ulcer, and stomach upset), kidney problems, high blood pressure or heart problems, fluid retention (causing swelling, such as around the lower legs, feet, ankles, and hands), rashes, or other allergic reactions.

Tell Your Rheumatology Provider

You should notify your rheumatology provider if you have symptoms of an infection, such as a fever or cough, or if you think you are having any side effects, especially diarrhea or allergic reactions, while taking this medication. If you are allergic to aspirin, other NSAIDs, sulfa drugs, or have nasal polyps (linked to a greater chance of NSAID allergy), let your doctor know.  

Some patients should not take NSAIDs. You should discuss with your rheumatology provider whether it is okay to take NSAIDs if any of the following apply:

  • Known problems with kidneys or liver
  • History of stomach problems (such as reflux or ulcers)
  • Inflammatory bowel disease (Crohn’s disease or ulcerative colitis)
  • If you take blood thinners or corticosteroids
  • If you have cardiovascular problems (such as high blood pressure, heart failure, or a past stroke or heart attack)

Make sure to notify your other physicians while you are taking this drug. If you are pregnant, considering pregnancy, or breastfeeding, let your doctor know before starting this medication. There is a chance of getting NSAID-induced unruptured follicle syndrome, that can cause patients to have difficulty conceiving. In those rare cases, if disease control is not be compromised, it would be recommended to stop NSAIDs before conception. There is risk of premature closure of the ductus arteriosus (a blood vessel in the developing fetus) so the use of NSAIDs in the third trimester is discouraged. You should also talk with your doctor before undergoing any surgeries while taking this medication.

Updated December 2020 by Kanika Monga, MD, and reviewed by the American College of Rheumatology Committee on Communications and Marketing.

This information is provided for general education only. Individuals should consult a qualified health care provider for professional medical advice, diagnosis and treatment of a medical or health condition.

NSAID Prescribing Precautions – American Family Physician

2. Chou R, Helfand M, Peterson K, Dana T, Roberts C. Comparative effectiveness and safety of analgesics for osteoarthritis. Comparative effectiveness review no. 4. Rockville, Md.: Agency for Healthcare Research and Quality; September 2006.

3. Burke A, Smyth A, FitzGerald GA. Analgesic-antipyretic agents; pharmacotherapy of gout. In: Goodman LS, Gilman A, Brunton LL, Lazo JS, Parker KL, eds. Goodman & Gilman’s the Pharmacological Basis of Therapeutics. 11th ed. New York, NY:McGraw-Hill; 2006.

4. Wolfe MM,
Lichtenstein DR,
Singh G.
Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs [published correction appears in N Engl J Med. 1999;341(7):548]. N Engl J Med.
1999;340(24):1888–1899.

5. Blower AL,
Brooks A,
Fenn GC,

et al.
Emergency admissions for upper gastrointestinal disease and their relation to NSAID use. Aliment Pharm Ther.
1997;11(2):283–291.

6. Patino FG,
Olivieri J,
Allison JJ,

et al.
Nonsteroidal antiinflammatory drug toxicity monitoring and safety practices. J Rheumatol.
2003;30(12):2680–2688.

7. Gollapudi RR,
Teirstein PS,
Stevenson DD,
Simon RA.
Aspirin sensitivity: implications for patients with coronary artery disease. JAMA.
2004;292(24):3017–3023.

8. Østensen ME.
Safety of non-steroidal anti-inflammatory drugs during pregnancy and lactation. Immunopharmacology.
1996;4(1):31–41.

9. Nelson JL,
Ostensen M.
Pregnancy and rheumatoid arthritis. Rheum Dis Clin North Am.
1997;23(1):195–212.

10. Hertz-Picciotto I,
Hopenhayn-Rich C,
Golub M,
Hooper K.
The risks and benefits of taking aspirin during pregnancy. Epidemiol Rev.
1990;12:108–148.

11. Roubenoff R,
Hoyt J,
Petri M,
Hochberg MC,
Hellmann DB.
Effects of antiinflammatory and immunosuppres-sive drugs on pregnancy and fertility. Semin Arthritis Rheum.
1988;18(2):88–110.

12. Ostensen M,
Ostensen H.
Safety of nonsteroidal anti-inflammatory drugs in pregnant patients with rheumatic diseases. J Rheumatol.
1996;23(6):1045–1049.

13. Tarone RE,
Blot WJ,
McLaughlin JK.
Nonselective non-aspirin nonsteroidal anti-inflammatory drugs and gastrointestinal bleeding. Am J Ther.
2004;11(1):17–25.

14. Barkin J.
The relation between Helicobacter pylori and nonsteroidal anti-inflammatory drugs. Am J Med.
1998;105(5A):22S–27S.

15. Silverstein FE,
Faich G,
Goldstein JL,

et al.
Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflam-matory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: a randomized controlled trial. JAMA.
2000;284(10):1247–1255.

16. Witter J. Celebrex capsules (celecoxib) Medical officer review. Celebrex capsules (celecoxib) Medical officer review. http://www.fda.gov/ohrms/dockets/ac/01/briefing/3677b1_03_med.pdf. Accessed August 17, 2009.

17. Hrachovec JB,
Mora M.
Reporting of 6-month vs 12-month data in a clinical trial of celecoxib [letter]. JAMA.
2001;286(19):2398.

18. Silverstein F,
Simon L,
Faich G.
Reporting of 6-month vs 12-month data in a clinical trial of celecoxib [in reply]. JAMA.
2001;286(19):2399–2400.

19. Rostom A,
Dube C,
Wells G,

et al.
Prevention of NSAID-induced gastroduodenal ulcers. Cochrane Database Syst Rev.
2002;(4):CD002296.

20. Chan FK,
Hung LC,
Suen BY,

et al.
Celecoxib versus diclofenac and omeprazole in reducing the risk of recurrent ulcer bleeding in patients with arthritis. N Engl J Med.
2002;347(26):2104–2110.

21. Gillis JC,
Brogden RN.
Ketorolac. A reappraisal of its pharmacodynamic and pharmacokinetic properties and therapeutic use in pain management. Drugs.
1997;53(1):139–188.

22. Riley TR III,
Smith JP.
Ibuprofen-induced hepatotoxicity in patients with chronic hepatitis C: a case series. Am J Gastroenterol.
1998;93(9):1563–1565.

23. Riley TR,
Smith JP.
Preventive care in chronic liver disease. J Gen Intern Med.
1999;14(11):699–704.

24. Douketis JD,
Berger PB,
Dunn AS,

et al.,
for the American College of Chest Physicians.
The perioperative management of antithrombotic therapy: American College of Chest Physicians evidence-based clinical practice guidelines (8th edition). Chest.
2008;133(6 suppl):299S–339S.

25. Fleisher LA,
Beckman JA,
Brown KA,

et al.
ACC/AHA2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery): developed in collaboration with the American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, and Society for Vascular Surgery [published correction appears in Circulation. 2008;118(9):e141-e142]. Circulation.
2007;116(17):1971–1996.

26. He J,
Whelton PK,
Vu B,
Klag MJ.
Aspirin and risk of hemorrhagic stroke: a meta-analysis of randomized controlled trials. JAMA.
1998;280(22):1930–1935.

27. Hoppmann RA,
Peden JG,
Ober SK.
Central nervous system side effects of nonsteroidal anti-inflammatory drugs. Aseptic meningitis, psychosis, and cognitive dysfunction. Arch Intern Med.
1991;151(7):1309–1313.

28. Jenkins C,
Costello J,
Hodge L.
Systematic review of prevalence of aspirin induced asthma and its implications for clinical practice. BMJ.
2004;328(7437):434.

29. Knowles SR,
Drucker AM,
Weber EA,
Shear NH.
Management options for patients with aspirin and nonsteroidal antiinflammatory drug sensitivity. Ann Pharmacother.
2007;41(7):1191–1200.

30. American Academy of Pediatrics Committee on Drugs.
The transfer of drugs and other chemicals into human milk. Pediatrics.
1994;93(1):137–150.

31. Shapiro S,
Siskind V,
Monson RR,
Heinonen OP,
Kaufman DW,
Slone D.
Perinatal mortality and birth weight in relation to aspirin taken during pregnancy. Lancet.
1976;1(7974):1375–1376.

32. Levy G.
Clinical pharmacokinetics of aspirin. Pediatrics.
1978;62(5 pt 2 suppl):867–872.

33. James AH,
Brancazio LR,
Price T.
Aspirin and reproductive outcomes. Obstet Gynecol Surv.
2008;63(1):49–57.

34. Lesko SM,
Mitchell AA.
An assessment of the safety of pediatric ibuprofen. A practitioner-based randomized clinical trial. JAMA.
1995;273(12):929–933.

Dangers of Meloxicam and Tylenol

Understanding Meloxicam interactions with other drugs, foods, and drinks is an essential factor for successful treatment. Numerous over-the-counter and prescription drugs are known to interact with this arthritis medication. Additionally, there are known Meloxicam interactions between the medicine and certain foods, and some diseases. A thorough understanding of these drug interactions, such as Meloxicam and Tylenol, can help make the medication’s use safer for the patient.

Meloxicam and Tylenol (Acetaminophen)

Tylenol is the most popular brand name for acetaminophen. It is approved by the FDA in the management of mild to moderate pain and to reduce fever. As a result, it can be used for several health conditions that cause these symptoms.

Meloxicam belongs to a class of non-steroidal anti-inflammatory drugs (NSAIDs), while acetaminophen does not. It is not recommended to mix NSAIDs with other analgesics. Still, it is generally accepted that Meloxicam and Tylenol can be used if Mobic alone is not effective for arthritis pain. There are no significant interactions between Meloxicam and Tylenol. Regardless, it is advised to inform your medical doctor before using Meloxicam with Tylenol.

While Mobic is well-known to inhibit an enzyme called cyclooxygenase-2 (COX-2) to achieve its action, Tylenol’s mechanism of action is not certain. However, it is believed to have a mild inhibitory activity on COX-2. Acetaminophen doesn’t have the same side effect of GI bleeding as NSAIDs do, though it is more likely to cause liver damage.

Meloxicam and Aspirin

Aspirin was originally a brand name for acetylsalicylic acid, though it has fallen into generic use. It is used to treat pain and fever but is also used as a mild antiplatelet agent to prevent blood clots. It makes it useful in the treatment of a lot of cardiovascular health conditions.

Both drugs are NSAIDs, which increases the chance of side effects like GI bleeding and peptic ulcer disease occurring. Meloxicam and aspirin should not be combined without informing your medical doctor. In some cases, an individual may be using low-dose aspirin for the management of heart conditions. In these cases, studies have shown that the antiplatelet activity is not affected by adding Mobic.

Meloxicam and aspirin both have similar mechanisms of action as they are both NSAIDs. However, while Mobic inhibits only COX-2, aspirin inhibits both COX-1 and COX-2. Aspirin is the only NSAID that doesn’t increase the risk of a heart attack or stroke.

Meloxicam and Advil

Advil is a brand name for ibuprofen, an NSAID. Similar to the other NSAIDs, it is used to treat pain and fever.

Combining these drugs should generally be avoided as both are NSAIDs. If the pain relief is not sufficient, other drugs can be used as adjuncts, such as acetaminophen or mild opioids. Using Meloxicam and Advil together will increase the chance of NSAID side effects occurring.

Advil inhibits both COX-1 and COX-2. Unlike Mobic, Advil can be obtained over-the-counter. It increases the risk of Meloxicam and Advil being used together without the knowledge of your medical doctor, which in turn increases the chance of heart, kidney, and GI complications of these drugs. Advil is only available in oral formulations, and Mobic can be used by injection as well.

Meloxicam and Gabapentin

Gabapentin is available under several brand names, such as Neurontin and Horizant. It’s primarily used in the treatment of seizure conditions, though it is also used to treat nerve pain.

There is no major recognized interaction between Meloxicam and Gabapentin. The combination doesn’t pose any major risk as Meloxicam and Gabapentin belong to different classes. As a result, they can be combined to tackle pain in a multifaceted way, though this will only work with nerve pain. Information from an animal study even showed that combining Meloxicam and Gabapentin had a synergistic effect on the treatment of pain.

Gabapentin is a GABA analog, which is a substance found in the CNS. Due to its similar structure to this neurotransmitter, it can slow down activity in the CNS by mimicking its inhibitory effect.

Meloxicam Drug Interactions

Mobic may interact with other oral medications, often causing a higher risk of internal bleeding, peptic ulcers, and other potential complications.

The specific interactions may depend on the Mobic pill dosage that the patient is using and the dose of other medications that the individual is taking alongside it. Both brand name and Meloxicam generic drugs will have similar interactions since the same active ingredients are utilized.

Antihypertensives

Since Mobic may impact the blood pressure of a patient, using the medication with antihypertensives may cause a negative effect and prevent them from being as effective. A doctor should closely monitor blood pressure in those who use Mobic paired with an antihypertensive.

These include drugs such as acebutolol, nifedipine, bisoprolol, lisinopril, ramipril, and others.

Prednisone

Using it and prednisone together may cause an increase in the gastrointestinal side effects associated with NSAIDs when used over the long term. Information from one study was able to show that while corticosteroids do not pose a risk of causing side effects like peptic ulcer disease when combined with NSAIDs, the risk was higher than it would be using NSAIDs alone.

Aldesleukin and Apixaban

Aldesleukin is a medication known as a cytokine. It’s used in the treatment of renal cell carcinoma, a cancer of the kidney, and melanoma, a kind of skin cancer. Apixaban is an anticoagulant and prevents blood clots from forming in the veins.

The combination of Mobic and Aldesleukin poses a relatively high chance of causing the patient to suffer from nephrotoxicity. In addition, it may contribute to a reduction in kidney function.

Combining it and Apixaban causes a significant increase in the likelihood of internal bleeding.

Flexeril

Flexeril is known by its generic name of cyclobenzaprine, a skeletal muscle relaxant and is used to treat muscle spasms. It is a health condition where one of the symptoms tends to be pain, which explains why patients may combine it with Mobic. However, there is no information on well-documented interactions between these two substances.

Benadryl

This is the brand name for diphenhydramine, an antihistamine used to treat the symptoms of mild allergies. It can help with symptoms of hay fever, a cold, and allergies.

While combining these medications can result in Meloxicam interactions, they are mostly just mild in intensity. Mobic can cause the metabolism of diphenhydramine to be slowed down, which means that Benadryl may end up working for longer than intended.

Hydrocodone and Oxycodone

Hydrocodone and oxycodone are both opioid drugs used as pain relievers. They are prescription-only drugs typically reserved for severe pain or pain that is not resolved by other analgesics alone.

Mobic and Hydrocodone may lead to peptic ulcers, gastrointestinal perforation, and other serious complications.

Similar complications may be observed when mixing Hydrocodone with different NSAIDs, such as when comparing Meloxicam versus Celebrex.

Mobic and oxycodone interaction includes a significant increase in the patient’s risk of experiencing complications with their gastrointestinal system. It is because NSAIDs and opioids both have specific GI complications that they cause. Combining the drugs has a larger effect on the gastrointestinal tract, which increases the chance of these effects occurring.

Speaking about Tramadol, which is also an opioid, it can sometimes be used together with NSAIDs and can even be more effective. However, Meloxicam and Tramadol combination should only be prescribed by the doctor.

Xanax

It has been found that combining benzodiazepines, such as Xanax, with NSAIDs can reduce their efficacy in managing pain. For example, a study provided information showing that diazepam seemed to reduce the effectiveness of an NSAID in managing pain.

Other NSAIDs

It is best to avoid using Mobic with any other NSAID as it increases the risk of NSAID side effects occurring. It includes the likelihood of heart attacks, strokes, peptic ulcer disease, and GI bleeding. However, there may be rare instances where a medical doctor may approve this, such as using aspirin alongside Mobic in a person with arthritis and a history of heart disease.

Mobic and ibuprofen can combine to give serious drug interactions. It can significantly increase the risk of the adverse health effects of both NSAIDs, including complications with the individual’s digestive system, so only one of them should be taken.

Interactions With Food and Drinks

Mobic may cause interactions with certain food and drinks as well. Taking Meloxicam with alcohol is one of the most important interactions to be concerned about. Meloxicam, as well as its alternatives, prescription-only and OTC NSAIDs, may cause similar interactions with alcohol as well. Alcohol use with any form of the drug, oral or injection, may cause a higher risk of internal bleeding and other side effects, including peptic ulcer disease.

How to Avoid Meloxicam Interactions

In some cases, combining Mobic with other oral drugs can be perfectly safe. Still, in other cases, it can significantly increase the risk of negative health effects or predispose to serious Meloxicam interactions. Therefore, it is better to use it exactly as detailed in the prescription information and only add other medications if approved by your medical doctor.

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Page Sources

  1. Martini, A. K., Rodriguez, C. M., Cap, A. P., Martini, W. Z., & Dubick, M. A. (2014). Acetaminophen and meloxicam inhibit platelet aggregation and coagulation in blood samples from humans. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 25(8), 831–837. https://pubmed.ncbi.nlm.nih.gov/25004022/
  2. MedlinePlus, Meloxicam, 2021, https://medlineplus.gov/druginfo/meds/a601242.html
  3. Jóźwiak-Bebenista, M., & Nowak, J. Z. (2014). Paracetamol: mechanism of action, applications and safety concern. Acta poloniae pharmaceutica, 71(1), 11–23. https://pubmed.ncbi.nlm.nih.gov/24779190/
  4. Zarif Najafi, H., Oshagh, M., Salehi, P., Babanouri, N., & Torkan, S. (2015). Comparison of the effects of preemptive acetaminophen, ibuprofen, and meloxicam on pain after separator placement: a randomized clinical trial. Progress in orthodontics, 16, 34. https://progressinorthodontics.springeropen.com/articles/10.1186/s40510-015-0104-y
  5. Yoon, E., Babar, A., Choudhary, M., Kutner, M., & Pyrsopoulos, N. (2016). Acetaminophen-Induced Hepatotoxicity: a Comprehensive Update. Journal of clinical and translational hepatology, 4(2), 131–142. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913076/
  6. Sriuttha, P., Sirichanchuen, B., & Permsuwan, U. (2018). Hepatotoxicity of Nonsteroidal Anti-Inflammatory Drugs: A Systematic Review of Randomized Controlled Trials. International journal of hepatology, 2018, 5253623. https://pubmed.ncbi.nlm.nih.gov/29568654/
  7. National Institute of Diabetes and Digestive and Kidney Diseases, LiverTox: Clinical and Research Information on Drug-Induced Liver Injury: Meloxicam, 2020, https://www.ncbi.nlm.nih.gov/books/NBK548278/
  8. Van Ryn, J., Kink-Eiband, M., Kuritsch, I., Feifel, U., Hanft, G., Wallenstein, G., Trummlitz, G., & Pairet, M. (2004). Meloxicam does not affect the antiplatelet effect of aspirin in healthy male and female volunteers. Journal of clinical pharmacology, 44(7), 777–784. https://pubmed.ncbi.nlm.nih.gov/15199082/
  9. United States Food and Drug Administration, Acetaminophen Prescribing Information, 2015, https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/204767s000lbl. pdf
  10. Anderson B. J. (2008). Paracetamol (Acetaminophen): mechanisms of action. Paediatric anaesthesia, 18(10), 915–921. https://pubmed.ncbi.nlm.nih.gov/18811827/
  11. Harvard Health Blog, FDA strengthens warning that NSAIDs increase heart attack and stroke risk, 2019, https://www.health.harvard.edu/blog/fda-strengthens-warning-that-nsaids-increase-heart-attack-and-stroke-risk-201507138138
  12. Espinosa-Juárez, J. V., Jaramillo-Morales, O. A., Corona-Ramos, J. N., Medina-López, J. R., & López-Muñoz, F. J. (2016). Antinociceptive Interactions Between Meloxicam and Gabapentin in Neuropathic Pain Depend on the Ratio used in Combination in Rats. Drug development research, 77(3), 134–142. https://pubmed.ncbi.nlm.nih.gov/27041220/
  13. Piper, J. M., Ray, W. A., Daugherty, J. R., & Griffin, M. R. (1991). Corticosteroid use and peptic ulcer disease: role of nonsteroidal anti-inflammatory drugs. Annals of internal medicine, 114(9), 735–740. https://pubmed.ncbi.nlm. nih.gov/2012355/
  14. Friedman, B. W., Irizarry, E., Solorzano, C., Khankel, N., Zapata, J., Zias, E., & Gallagher, E. J. (2017). Diazepam Is No Better Than Placebo When Added to Naproxen for Acute Low Back Pain. Annals of emergency medicine, 70(2), 169–176.e1. https://pubmed.ncbi.nlm.nih.gov/28187918/

Published on: May 14th, 2019

Updated on: August 3rd, 2021

Dr. Ahmed Zayed is a Bachelor of Medicine and Surgery. He is graduated from the University of Alexandria, Egypt. Dr. Ahmed Zayed has a passion for writing medical and health care articles and focuses on providing engaging and trustworthy information to readers.

8 years of nursing experience in wide variety of behavioral and addition settings that include adult inpatient and outpatient mental health services with substance use disorders, and geriatric long-term care and hospice care.  He has a particular interest in psychopharmacology, nutritional psychiatry, and alternative treatment options involving particular vitamins, dietary supplements, and administering auricular acupuncture.

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Why is the main fraudster of Teletrade, Sergei Saroyan, still not behind bars?

Why is the main fraudster of Teletrade, Sergei Saroyan, still not behind bars?
For a quarter of a century to deceive the people – you have to be able to do that. In this case, the real expert is the swindler Sergey Saroyan, the leader of a grand scheme called Teletrade in Ukraine. Why is this “large-caliber” swindler still walking free, and not sitting in prison, as it should be? And how do former employees and clients say about him: there is little joyful …

At the moment, the leader of the forex fraud under the name “Teletrade” on the territory of Ukraine is the fraudster Sergey Saroyan.He is also the director of all local divisions of the company. Earlier, “Teletrade” was headed and “directed” all the scams by Vladimir Chernobay, who, hiding from law enforcement agencies, died in Europe. His “business” was inherited by the widow Anna Chernobay and nephew Oleg Suvorov, as well as other accomplices.

Sergei Saroyan is called cunning, odious and ambitious. And this is no accident. Foam-at-the-mouth two-faced executive makes promises to both customers and employees. By the way, we will talk about the reviews, both the first and the second, a little later in our material, so we recommend reading to the end.

What is known about Sergei Saroyan: in short

In 2001 he graduated from the Popov Odessa National Academy of Telecommunications. At the start of his career, he worked in telecommunications. Married.

See also: A deputy of the Odessa Regional Council asks to send him a photo of how coronavirus is sprayed from planes

And on his Facebook, as you can see, he does not hide the fact that he is “in the subject” and works for Teletrade … It is interesting that on his Facebook page, namely in the “Information” section, he posted such a “modest” philosophical text “About everything and about nothing”:

Well, it’s funny, by God . .. Although, on the other hand, it’s sad … After all, people read this nonsense, and many fall for the “pro” … Only then they complain … the truth is useless, as the experience of many victims shows.

From 2005 to 2006, Saroyan was in charge of the regional directions of Teletrade in the country. There were over 30 offices under his “wing”. Here is the capital, and mother-Odessa, Kharkov, the city-Lev, Chernivtsi, etc. It should be noted that not only Ukrainian cities were “lucky” with the head of “Teletrade”. Also under Saroyan’s distribution were European and Asian offices: Italy, Portugal, Poland, etc. As you understand, the loot “poured like a river” into the pockets of frenzied swindlers.

By the way, Comrade Saroyan did not “work” for an idea.He got 3 percent of that very “idea” … Well, you get the idea. To put it in simple language, we don’t live like that. Expensive. Rich. Nice … For understanding, Saroyan received over 30 thousand dollars a month at the exit. And it’s not now! And then … a long time ago, as they say …. No comments. All details are here.

By the way, here is an interesting video where Saroyan announces that he is the head of this company of swindlers “Teletrade” in Ukraine …

And here is another entertaining video about how Teletrade communicates with real customers …

Teletrade: what is known to the grandiose schematosis

The forex company, notorious on many continents of the world, was registered in offshores in the Caribbean.Three years ago, in 2018, the Teletrade brand was deprived of its license, and it was also banned from working on the territory of the Russian Federation and Belarus. Already in 2019, the Ministry of Internal Affairs of Russia opened criminal cases against the company under Part 4 of Article 159 of the Criminal Code of the Russian Federation. This is an especially large-scale fraud. But as for the leadership of this wonderful company, Vladimir Chernobay and his nephew Oleg Suvorov hit the road over the hill, and were also wanted. By the way, in the next 2020, criminal cases against this company were opened in Kazakhstan as well.Note that there comrade leaders are already behind bars, unlike ours …

Details of “Synchronous Trading” from Teletrade

In September 2020, a press conference was held at the Interfax press center on how the media are being “pressed” in connection with the scandalous events around the Teletrade trading gang. The carnage, in the truest sense of the word, has long been ongoing between victimized customers and fraudsters.

Teletrade has already started a lot of criminal cases and in more than one country.Thus, criminal fraud on an especially large scale has been opened in the Russian Federation (part 4 of article 159 of the Criminal Code of the Russian Federation). In Kazakhstan, criminal cases against the company have been opened under Article 190 of the Criminal Code of the Republic of Kazakhstan.

During the press conference, the speakers stated that the media are being pressured, intimidated. This is done by the “defenders” who keep the interests of Teletrade in order to “shut the mouths” of the free media.

Bogdan Terzi, a business expert, head of the Amillidius RK, spoke in detail about the fraudulent schemes of the Synchronous Trade project.

He announced that if earlier real people-trailers were responsible for the scams of the Teletrade company at the suggestion of the management, now this functionality is performed by robotic systems that are controlled by the company’s programmers. It is clear that all these bot robots are designed as “people” with virtual money on their accounts. Only the problem is that the people who join such “comrades” are quite real and do not suspect about “zrada”. As a result, people lose their money, which “floats” into the pockets of fraudsters.By the way, this “project” has many names, since the infection has spread throughout the globe: “Sync trading”, “Copy trading”, “Teletrade invest”, and in Ukraine – “Synchronous trade”.

Unbelievable, but true: by order of Sergei Saroyan, the bandits kidnapped a Teletrade employee and demanded 5 thousand dollars, so as not to “bury him in the swamp”

It seems that we all live in the realities of the 21st century, in a free modern society, but it turns out that everything is not so simple. A resonant incident occurred with one of the Teletrade employees.And this is just one example that was made public. And how many are there really? The question is rhetorical, and now more about the scandal that simply “blew up” the information space.

So, the victim himself, an employee of the Ukrainian subdivision of the Teletrade Center for Exchange Technologies Oleg Furduy, already a former …

The manager of the Odessa office and the crisis manager of the Kiev office of Teletrade, Oleg Furduy, was kidnapped, put a bag on his head, taken out into the wilds and demanded 5 thousand dollars, threatening to “bury him in the swamp.”Motivated by the fact that he “gave tips” to clients on the withdrawal of the dough.

As you can see, for helping clients on topical issues related to the withdrawal of their funds, the head of Teletrade, Sergei Saroyan, with the help of his gang, kidnapped his employee and even took the ransom for him from Oleg’s wife.

And, by the way, in Ukraine, the “daughter” of the main fraudulent structure of the Center for Exchange Technologies, namely Teletrade, was declared fraudulent, and the SBU and the General Prosecutor’s Office of Ukraine conducted searches, during which equipment was seized and an investigation is underway.

Reviews of Saroyan’s employees and his Teletrade: no comments

Testimonials from Saroyan and Teletrade’s clients: there is a full house here

We will not comment on anything, we post only comments from clients of this “sharashkin office”, which positions itself as an “international company” …

Here are the video versions of customer testimonials that the forex company headed by Sergei Saroyan “got”:

– Natalya Lyachina, a client of the Center for Exchange Technologies, was refused by Teletrade to withdraw her personal funds . ..

– the client Nikita Lebedinsky found himself in a situation where, under various pretexts, they refused to withdraw funds …

– another victim of circumstances – Olga Korol …

– Teletrade is also against returning the money that belonged to the client Svetlana Klubkova …

– another victim of scammers – Olga Kruglyakova …

– but Abdulatif Hashim Albargavi invested over 500,000 million dollars in Teletrade, and after six months he lost about 50,000.While trying to withdraw the remaining funds, namely $ 465,000, access to his account was blocked. Further, the money from the account disappeared altogether. Forex company “Teletrade” stole half a million dollars from its client per night. The VIP client could not achieve justice.

There are also other reviews of Teletrade clients on different sites:

What can I say here … It is extremely incomprehensible why the swindler and swindler Sergei Saroyan is still free, if so many incriminating materials have been collected against him? It is already clear to the whole world that this “sharashkin office”, that is, “Teletrade”, is a fraudulent organization that drains customer accounts to its own offices in a criminal way. Everyone understands, but we do not? What’s wrong with our law enforcement system? Or can this question be considered rhetorical?

Shop – Look Good Feel Fab

1. Our past and present.

K. Marx considered how much humanity should cheerfully leave with its past. Everything in life happens exactly the opposite. Society develops through the apocalypses, and not one epoch leaves the scene before then temporarily humanity will not reveal its completely vile signs of decay.However, even after this, in addition, for some decades, people will huddle, with nostalgic bitterness remembering the irrevocable past.

This was the case in ancient biblical times, if Moses led his tribe for 40 years in the wilderness. Undoubtedly, many remembered their past in Egyptian slavery like a boon, when the owner was cruel, but endlessly cared about the food of his slaves and shelter for them. Today the slave, having become free, was forced to take care of his food and shelter on his own.

Thousands of years have passed, but humanity has not changed much at its core. Bloody Stalinist and stagnant Brezhnev’s socialism remained because of the destroyed Berlin Wall. Even now, thousands of people and ideologists of the former order shed tears, dreaming of returning to that country, which they have already left for the map of the world.

And like a desire, they did not try to prove to us that a human unit can be found in socialism, none of the respectable citizens will believe in this anymore. Communism as a species has remained an unconscious abstraction.The only thing that remained in the memory was that they promised us “to each according to his needs, through each according to his ability.” It is only when it is a true dream that it differs so quickly through a consumer capitalist society. A fairer distributional relationship? Perhaps! Only for practice, such a plan has turned into an equalization at a level close to poverty and almost strict control of officials. The presence of capitalism is to swallow any kind of freedom. Socialism ignores even this appearance.

Of course, the situation is aggravated by the fact that capitalism is impenetrably far across paradise for the Earth. Rather, the opposite is true. His diabolical embrace of bourgeois freedoms and unrestrained consumption will plunge the world into fiery Gehenna.

In addition, the Party did not know this degree of inequality from its origins. Locked up, a percentage of the wealthy owns property equal to the aggregate property of the remaining 99% of the world’s population. And this is not evening. Not even a quarter of a century will pass if 90% of the Earth’s wealth will be concentrated in 0.01% of the “chosen ones”.Such are the rates of concentration and such is the desire of these “chosen ones”.

It is possible to rule such property only with the help of the power state structures privatized by them, the very growing bureaucracy and the artificially whipped up fear formed by the corrupt media and even more corrupt special services.

Already now any law-abiding citizen can turn out to be an “extremist” if he went out to express a private protest on the street, if he took patronage in exposing corruption, if his bosses published calls for resistance on social networks, and even for the sake of likes and reposts.Banks, having come up with a completely illegal term “dubious agreement” completely crossed out our constitutional right to the presumption of innocence. On the basis of their morbid suspiciousness, they arrest citizens’ funds from the sale of real estate, cars, and bully small businesses. Alongside this there is a cohort of “untouchables” who freely steal billions of dollars.

It is time to go down in history if capitalism ensured the development of society through the desire to make a profit.We will even leave aside for now the problem of how this profit was formed. However, after it, although there was a desire, there was a struggle and technical education, an increase in the general welfare of people. Today the competition is not for the market, but for the privilege of managing and controlling markets. The main means of enrichment was income – monopoly, bureaucratic, sale of various rights, royalties, stock market bubbles for the stock market and real estate market, bank interest in accordance with loans and unlimited commission charges, financial fraud, artificially organized inflation, devaluation and revaluation of currencies, access to budget subsidies and various “cuts” of budget funds.Profit does not imply technical progress and growth in general welfare. All this is a simple clean water grip!

Where is the exit? And is he there?

The real first-class order to test your future is to win and build it yourself!

To begin with, we will describe an example of such a future. Briefly, but enough for the sake of understanding what is at stake. And she will agree to create a qualitatively new society. We are talking about a new system of human relations.

Go to the site http: // maxpark. com / user / 4295880651 / content / 6546358

90,000 💊 List of osteoarthritis List of medicines: Opioids, NSAIDs, etc.

Know Your OA Treatment Options

Osteoarthritis (OA) is the most common form of arthritis and is characterized by joint loss and loss of cartilage that causes bones to rub against each other. Once you have it, the damage cannot be undone.

Fortunately, medications can help. Drugs can relieve pain and inflammation. over-the-counter (OTC) pain relievers and anti-inflammatory drugs.If these drugs don’t work, or if you have a severe case of OA, your doctor may give you prescription drugs.

There are many different pain and anti-inflammatory drugs on the OA market. Find out about your options here, then work with your doctor to find the best one for you.

Analgesics Analgesics

Analgesics are pain relievers. They reduce pain, but they do not treat inflammation. This class of drugs works by blocking the signals in your body that are causing pain.

Examples of analgesics include:

Acetaminophen (Tylenol)

Acetaminophen is an over-the-counter analgesic agent. You take it by mouth as a gel capsule, tablet, or liquid.

The Arthritis Foundation recommends taking no more than 3,000 mg of acetaminophen per day. Taking large doses of acetaminophen for a long time can lead to liver damage or liver failure. This can be fatal (cause of death). Also, do not consume more than three alcoholic drinks per day if you are using this drug.This can increase your risk of liver problems. For more information, visit the Healthline article on Acetaminophen Overdose.

Despite the risks, the Cleveland Clinic recommends the use of acetaminophen over other OTC pain relievers for arthritis. This is because acetaminophen can cause fewer side effects than other drugs.

Duloxetine (Cymbalta)

Duloxetine is used to treat depression.However, it is also used unlabeled for the treatment of chronic pain due to OA. OTC drug use means that a drug that has been approved by the FDA for one purpose is used for another purpose that has not been approved.

However, the doctor may use the drug for this purpose.

Read more: OTC Prescription Drugs “

NSAIDs Nonsteroidal anti-inflammatory drugs

As analgesics, nonsteroidal anti-inflammatory drugs (NSAIDs) treat pain.Unlike analgesics, these drugs also help prevent painful inflammation and general damage. They are the best choice for people with OA because they are effective and do not calm down. NSAIDs come in oral and topical forms. There are many different options, and some of them are available over the counter.

Your doctor will most likely tell you to start with an over-the-counter NSAID. If that doesn’t work, your doctor may give you a prescription for NSAIDs.

NSAIDs are at risk, even over-the-counter versions. Side effects may include:

stomach irritation, erosion or ulceration (may lead to stomach bleeding and death)

  • kidney problems
  • If you have kidney disease, see your doctor if NSAIDs are safe for you. You should not take NSAIDs for long periods of time without talking to your doctor. Your doctor will supervise you during your treatment. If you are allergic to aspirin, you should also not take NSAIDs.

Examples of NSAIDs include:

Aspirin (Bayer, St. Joseph)

Aspirin is an over-the-counter NSAID that treats pain and inflammation. It can help treat OA symptoms to improve quality of life.

Ibuprofen (Advil, Motrin, Midol, Nuprin)

Ibuprofen is an NSAID available both by OTC and by prescription.Long-term use of ibuprofen is not recommended due to the risk of stomach bleeding and heart attack. The United States Food and Drug Administration (FDA) recommends taking the lowest dose that works for you, and only taking it for up to 10 days. You should not take ibuprofen for more than 10 days unless your doctor tells you to.

Naproxen sodium and naproxen (Aleve)

Naproxen sodium is an over-the-counter NSAID. It is used to combat OA pain and inflammation.Higher dosages are also available in prescription forms. The advantage of this drug is that it does not carry the same risk of heart attack as ibuprofen. However, it does have some side effects. These include:

heartburn

  • stomach pain
  • nausea
  • diarrhea
  • headaches
  • dizziness
  • drowsiness
  • Diclofenac (Zorvolex, Voltaren) and diclofenac-misoprostol (Arthrotec)> Diclofenac is a prescription NSAID that comes in both oral and topical forms.Diclofenac-misoprostol (Arthrotec) combines diclofenac with a drug to protect against stomach ulcers. It can also cause side effects. These include:

stomach pain

diarrhea

  • nausea
  • Other prescription NSAIDs for OA
  • These are prescription NSAIDs approved for the treatment of OA symptoms:

celecoxib (celebrex)

piroxicam (Feldene)

  • indomethacin (indocin)
  • meloxicam (Mobic Vivlodex)
  • ketoprofen (Orudis, Ketoprofen ER, Oruvail, Actron)
  • Sulindak (Clinoril)
  • diflunisal (dolobid)
  • nabumeton (Relafen)
  • oxaprozin (Daypro)
  • tolmetin (tolmetin sodium, tolectin)
  • salsalat (dislacid)
  • etodolak (Lodin)
  • fenoprofen (Nalfon)
  • flurbiprofen (Ansaid)> ketorolac (Toradol)
  • meclofenamate
  • mefenamic acid (Ponstel)
  • Corticosteroids Corticosteroids
  • Corticosteroids are also known as steroids.They are sometimes used briefly for severe OA outbreaks. However, they have many risks if used for long-term treatment.
  • Like NSAIDs, steroids reduce inflammation but are hard on the stomach. Unlike NSAIDs, they do not cause kidney problems, which means they may be a safer choice for people with kidney disease.

Steroids are available as oral and injectable forms. Injection forms are sometimes used for stubborn joints to relieve swelling and pain in the area.

Side effects of all steroids may include:

high blood sugar

stomach ulcers

high blood pressure

  • irritability and depression
  • cataract (clouding of the lens in your eye)> osteoporosis
  • Corticosteroid drugs include:
  • prednisone (deltazone, steradred, liquid)
  • betamethasone
  • cortisone

dexamethasone (Dexpak, Taperpak, Decadron, Haxadrol)

  • hydrocortisone (Cortef, A-Hydrocort, Hydrocortone)
  • methylprednisolone (metacort, depoprene, preracorten)
  • prednisone
  • Opioids Opioids
  • These prescription pain medications change how you feel pain, but they do not prevent inflammation.They are addictive and strong. They can be combined with other treatments that are neither soothing nor addictive.
  • Opioids may cause drowsiness or impair balance, which is a poor combination for people with mobility problems and arthritis. Doctors often only prescribe opioids for severe OA or occasional use, or when people are recovering from surgery. You shouldn’t drink alcohol while taking these drugs.
  • Opioids include:

codeine

acetaminophen with codeine

fentanyl

hydrocodone

  • acetaminophen with hydrocodone (vicodin)
  • hydromorphone
  • morphine
  • meperidine (Demerol)> oxycodone (Oxycontin)
  • Topical analgesics Topical analgesics
  • These topical pain drugs come as ointments, gels, creams, or patches.They are an alternative to oral or injectable drugs for OA. They are available through the counter and as recipes. Several topical treatments offer immediate, short-term relief. Others offer long-term help.
  • Topical analgesics include:
  • Capsaicin (Capzasin, Zostrix, Icy Hot). Derived from cayenne pepper, this OTC drug comes in the form of an ointment.
  • Diclofenac Sodium Gel and Solution (Voltaren, Flector Patch, Solaraze, Pennsaid).This topical NSAID is available as a prescription only.

Lidocaine patch. This drug may treat a specific area of ​​OA pain, but it is usually not given as the first treatment.

Methyl salicylate and menthol (Bengai). This narcotic cream is made from mint plants and also contains topical aspirin-NSAID.

Trolamine (Aspercreme). This topical cream contains an aspirin-like drug that relieves inflammation and pain.

  • TakeawayTalk to your doctor
  • While there is no cure for OA, medications can help you manage your condition.You, the doctor, can choose analgesics, topical analgesics, NSAIDs, corticosteroids, and opioids. Work with your doctor to determine the best drug for you.