Side effects, dosage, uses, and more

1. Tamsulosin oral capsule is available as a brand-name drug and a generic drug. Brand name: Flomax.
2. Tamsulosin comes only as a capsule you take by mouth.
3. Tamsulosin oral capsule is used to treat the symptoms of benign prostatic hyperplasia (BPH).

Tamsulosin is a prescription drug. It comes as a capsule you take by mouth.

Tamsulosin oral capsule is available as the brand-name drug Flomax. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug.

This drug may be used as part of a combination therapy. That means you may need to take it with other drugs.

Why it’s used

Tamsulosin is used to treat the symptoms of benign prostatic hyperplasia (BPH). BPH is a condition that can occur in men. With BPH, the prostate is enlarged but isn’t cancerous.

Symptoms of BPH include trouble urinating, and a frequent or urgent need to urinate that often occurs at night.

How it works

Tamsulosin belongs to a class of drugs called alpha-adrenergic blockers. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Tamsulosin works by relaxing the muscles in your bladder and prostate. This helps improve the flow of your urine.

Tamsulosin oral capsule doesn’t cause drowsiness, but it can cause other side effects.

More common side effects

The more common side effects that can occur with tamsulosin include:

• headache
• dizziness
• runny nose
• diarrhea
• cough
• decreased semen
• loss of energy or muscle strength
• sore throat or trouble swallowing
• back or chest pain
• tiredness
• nausea

If these side effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Serious side effects

Call your doctor right away if you have serious side effects. Call 911or local emergency services if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

• abnormal ejaculation
• priapism (painful, long-lasting erection)
• flu-like symptoms
• blurred vision
• low blood pressure that causes you to feel lightheaded, faint, or dizzy when changing positions
• allergic reaction, with trouble breathing, fever, swelling of your throat or tongue, rash, itching, or hives

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

Tamsulosin oral capsule can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Examples of drugs that can cause interactions with tamsulosin are listed below.

Acid-blocking drug

Taking cimetidine with tamsulosin can increase the levels of tamsulosin in your body. This raises your risk of side effects from tamsulosin. These drugs should be used together cautiously.

Antibiotic

Taking erythromycin with tamsulosin could increase the levels of tamsulosin in your body. This can raise your risk of side effects from tamsulosin. These drugs should be used together cautiously.

Antidepressant (SSRI)

Taking paroxetine with tamsulosin can increase the levels of tamsulosin in your body. This raises your risk of side effects from tamsulosin. These drugs should be used together cautiously.

Antifungal drugs

Taking certain antifungals with tamsulosin can increase the levels of tamsulosin in your body. This raises your risk of side effects from tamsulosin. Examples of these drugs include:

• terbinafine (these drugs should be used together cautiously)
• ketoconazole (do not use this drug with tamsulosin)

Erectile dysfunction (ED) drugs

Taking ED drugs with tamsulosin can cause very low blood pressure. Examples of these drugs include:

• sildenafil
• tadalafil
• vardenafil

Other benign prostatic hyperplasia drug

Taking alfuzosin with tamsulosin could worsen low blood pressure, a side effect of tamsulosin. Symptoms can include dizziness, fainting, and falls.

Alpha blockers

Taking drugs called alpha blockers with tamsulosin can cause very low blood pressure. Examples of alpha blockers include:

• doxazosin
• prazosin

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

This dosage information is for tamsulosin oral capsule. All possible dosages and forms may not be included here. Your doctor will tell you what dosage is right for you. Your dosage, form, and how often you take the drug will depend on:

• your age
• the condition being treated
• the severity of your condition
• other medical conditions you have
• how you react to the first dose

Dosage for benign prostatic hyperplasia (BPH)

Generic: Tamsulosin

• Form: oral capsule
• Strength: 0. 4 mg

Brand: Flomax

• Form: oral capsule
• Strength: 0.4 mg

Adult dosage (ages 18–64 years)

Typical dosage: 0.4-mg capsule daily.

Dosage increase: If your body doesn’t respond to the 0.4-mg dose after two to four weeks, your dosage may be increased to 0.8 mg daily.

Senior dosage (ages 65 years and older)

Your body may process this drug more slowly. Your doctor may start you on a lowered dosage so that levels of the drug don’t build up too high in your body. High levels of this drug in your body can be dangerous.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.

Tamsulosin oral capsule is used for long-term treatment. It comes with risks if you don’t take it as prescribed.

If you stop taking the drug suddenly or don’t take it at all: Your BPH symptoms won’t improve. If you stop taking this drug for several days, talk to your doctor before starting again.

If you miss doses or don’t take the drug on schedule: Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.

If you take too much: Taking too much of this drug can cause low blood pressure. This can be dangerous.

If you think you’ve taken too much of this drug, call your doctor or seek guidance from the American Association of Poison Control Centers at 1-800-222-1222 or through their online tool. But if your symptoms are severe, call 911 or go to the nearest emergency room right away.

What to do if you miss a dose: Take your dose as soon as you remember. But if you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects.

How to tell if the drug is working: You should see a decrease in the symptoms of BPH. You may need to urinate less often, have less urgency to urinate, or have a stronger urine stream.

As with all medications, the costs of tamsulosin can vary.

Keep these considerations in mind if your doctor prescribes tamsulosin for you.

General

• You should take this drug 30 minutes after a meal, at the same time each day.
• Don’t crush or cut the capsule.

Storage

• Store this drug at room temperature between 59°F and 86°F (15°C and 30°C).
• Don’t freeze this medication.
• Keep this drug away from light.
• Don’t store this medication in moist or damp areas, such as bathrooms.

Refills

A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

Travel

When traveling with your medication:

• Always carry your medication with you. When flying, never put it into a checked bag. Keep it in your carry-on bag.
• Don’t worry about airport X-ray machines. They can’t harm your medication.
• You may need to show airport staff the pharmacy label for your medication. Always carry the original prescription-labeled container with you.
• Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold.

Clinical monitoring

BPH can occur with more serious conditions such as prostate cancer. Before starting treatment with tamsulosin, talk to your doctor about being screened for prostate cancer.

You will have regular checkups with your doctor. During these visits, your doctor will check whether your symptoms of BPH have improved.

There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other options that may work for you.

• Low blood pressure warning: Tamsulosin can cause you to feel dizzy or cause a drop in your blood pressure when you stand up after sitting or lying down. After taking your first dose or an increased dose, be sure you’re aware of how tamsulosin affects you before you perform any activity that could cause injury.
• Priapism warning: Rarely, tamsulosin can cause priapism. This is a persistent, painful erection that isn’t related to sexual activity. If you have priapism, contact your doctor right away. If priapism isn’t treated, it could lead to permanent impotence (not being able to have an erection).
• Skin reactions warning: Though rare, this drug can cause severe skin reactions, including a serious condition called Stevens-Johnson syndrome. These skin reactions can cause raised welts, facial swelling, fever, and trouble breathing. See a doctor right away or call 911 if you have signs of a sudden or severe skin reaction after taking this drug.
• Intraoperative floppy iris syndrome (IFIS) warning: IFIS is a complication that can occur during surgery for cataracts or glaucoma. Although rare, this problem has been reported with people taking tamsulosin. If you need to have cataract or glaucoma surgery, be sure to tell your doctor or surgeon that you’re taking tamsulosin.

This drug comes with several warnings.

Allergy warning

Tamsulosin can cause severe allergic reactions, such as a serious condition called Stevens-Johnson syndrome. These reactions can cause symptoms including:

• trouble breathing
• swelling of your throat or tongue
• rash, itching, hives

If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 911 or go to the nearest emergency room.

Don’t take this drug again if you’ve ever had an allergic reaction to it or to sulfa. Taking it again could be fatal (cause death). Sulfa is an ingredient found in certain drugs. Tell your doctor if you’ve had a serious or life-threatening allergic reaction to sulfa.

Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

Flomax vs Tamsulosin Comparison – Drugs.

com

Flomax vs Tamsulosin Comparison – Drugs.com
Skip to main content

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.

</p> <p> Flomax may also be used for purposes not listed in this comparison guide. </p> ”> Prescription only Flomax restores urine flow in men with BPH but may cause a drop in blood pressure when going from a sitting to a standing position. Prescribed for Benign Prostatic Hyperplasia. Flomax may also be… View more	</p> <p> Prescribed for Benign Prostatic Hyperplasia. </p> <p> May also be prescribed off label for Urinary Tract Stones. </p> ”> Prescription only Tamsulosin improves the symptoms of BPH such as urine flow, hesitancy, and incomplete bladder emptying, but may cause a drop in blood pressure when going from a sitting to a standing position, which… View more	Related suggestions Benign Prostatic Hyperplasia Finasteride Cialis Avodart Doxazosin Tadalafil Proscar Popular comparisons Flomax vs finasteride Flomax vs Cialis
More about Flomax (tamsulosin)	More about Tamsulosin
Generic Status
Lower-cost generic is available	Lower-cost generic is available
Ratings & Reviews
Flomax has an average rating of 5. 8 out of 10 from a total of 290 ratings on Drugs.com. 43% of reviewers reported a positive effect, while 33% reported a negative effect.	Tamsulosin has an average rating of 5.6 out of 10 from a total of 541 ratings on Drugs.com. 39% of reviewers reported a positive effect, while 35% reported a negative effect.
View all 290 reviews	View all 541 reviews
Drug Class
Alpha-adrenoreceptor antagonists	Alpha-adrenoreceptor antagonists
Side Effects
Common side effects include: dizziness nasal congestion paranasal sinus congestion rhinitis rhinorrhea seasonal allergic rhinitis See also: Flomax side effects in more detail.	Commonly reported side effects include: dizziness nasal congestion paranasal sinus congestion rhinitis rhinorrhea seasonal allergic rhinitis See also: tamsulosin side effects in more detail.
Pricing and Coupons * Prices are without insurance
Quantity 100 capsule Dosage 0.4 mg Per Unit* $10.34 Cost* $1,033.69 View all Flomax prices and generic prices	Quantity 50 each Dosage 0. 4 mg Per Unit* $0.59 Cost* $29.67 View all tamsulosin prices
Get free Discount Card	Get free Discount Card
Dosage Form(s) Available
Oral capsule	Oral capsule
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.
19 hours	19 hours
CSA Schedule ** View glossary of terms
Is not subject to the Controlled Substances Act.	Is not subject to the Controlled Substances Act.
Pregnancy Category
See the full pregnancy warnings document.	See the full pregnancy warnings document.
Drug Interactions
A total of 286 drugs are known to interact with Flomax: 32 major drug interactions (70 brand and generic names) 250 moderate drug interactions (972 brand and generic names) 4 minor drug interactions (16 brand and generic names)	A total of 286 drugs are known to interact with tamsulosin: 32 major drug interactions (70 brand and generic names) 250 moderate drug interactions (972 brand and generic names) 4 minor drug interactions (16 brand and generic names)
Alcohol/Food/Lifestyle Interactions
Food may affect the intestinal absorption of tamsulosin. You should take tamsulosin approximately… View more Ask your doctor before using alcohol together with tamsulosin. Using alcohol with tamsulosin can… View more	Food may affect the intestinal absorption of tamsulosin. You should take tamsulosin approximately… View more Ask your doctor before using alcohol together with tamsulosin. Using alcohol with tamsulosin can… View more
Disease Interactions
Glaucoma Hypotension End-stage renal disease Severe liver disease	Glaucoma Hypotension End-stage renal disease Severe liver disease
First Approval Date
April 15, 1997	April 15, 1997
WADA Class View World Anti-Doping Agency classifications.
N/A	N/A
More Information
Side effects Pregnancy warnings Breastfeeding warnings Dosage information Drug images Drug interactions Support group Pricing and coupons En Español	Side effects Pregnancy warnings Breastfeeding warnings Dosage information Drug images Drug interactions Support group Pricing and coupons En Español
Patient resources
Overview	Overview
Professional Resources
Prescribing information	Monograph (AHFS) Prescribing information

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Alpha-blockers for prostatitis: a list of effective drugs

Contents

• 1 Alpha-blockers for prostatitis: a list of drugs
  • 1.1 Why alpha-blockers are effective for prostatitis
  • 1.2 Drugs
  • 1.3 Tamsulosin
  • 1.4 Sildenafil
  • 1.5 Finasteride
  • 1.6 Dutasteride
  • 1.7 Terazosin
  • 1.8 Alfuzosin
  • 1.9 Silodosin
  • 1.10 Doxazosin
  • 1.11 Mirabegron
  • 1.12 Bisoprolol
  • 1.13 Methods of application
  • 1.14 Related videos:
  • 1.15 Q&A:
    • 9000 4
    • 1.15.0.1 Which drugs can be used for prostatitis?
    • 1.15.0.2 Which of the alpha-blockers is the most effective?

Alpha-blockers are effective drugs used in the treatment of prostatitis. This article provides a list of drugs that will help eliminate the symptoms of the disease and improve the patient’s quality of life. Review the list of alpha-blockers and choose the most suitable drug for your case.

Prostatitis is a common disease in men characterized by inflammation of the prostate gland. One of the treatments for prostatitis is the use of alpha-blockers. These drugs have the ability to relax the muscles of the prostate and bladder neck, which helps to reduce the symptoms of the disease and improve the patient’s quality of life. This article provides a list of effective drugs from the group of alpha-blockers, which are often used in the treatment of prostatitis.

One of the most common alpha-blockers used for prostatitis is Tamsulosin. This drug blocks alpha-adrenergic receptors in the prostate and bladder neck, causing them to relax. This reduces spasms and increased muscle tone, improves tissue enrichment with blood and urodynamics.

Other alpha blockers such as Doxazosin, Silosin, Terazosin and others can also be used, which also have the ability to relax the muscles of the prostate and bladder neck, improving prostatitis.

Why alpha-blockers are effective for prostatitis

Alpha-blockers are one of the important classes of drugs used in the treatment of prostatitis. These drugs have a positive effect on the state of the urinary system and can significantly improve the symptoms of the disease.

One of the main causes of prostatitis is a violation of blood microcirculation in the prostate. Alpha-blockers can eliminate this problem by dilating blood vessels and improving blood circulation in the pelvic organs.

Another important property of alpha-blockers is the ability to reduce muscle tension in the prostate and bladder. This improves the patency of the urinary tract and reduces the frequency of nighttime urination.

In addition, alpha-blockers have an anti-infective effect and can reduce inflammation in the prostate. This property of drugs of this class is especially important in the treatment of bacterial prostatitis.

It is important to note that the use of alpha-blockers in prostatitis can significantly improve the patient’s quality of life, reduce pain, normalize urination and eliminate discomfort in the prostate area.

But it must be remembered that self-treatment of prostatitis with alpha-blockers is not recommended. To select the optimal drug and dosage, you should contact a urologist who will conduct a detailed analysis of the patient’s condition and prescribe the appropriate treatment.

Medications

Alpha-blockers are effective drugs that help improve prostatitis. They act on alpha-adrenergic receptors and help to relax the smooth muscles of the prostate and bladder.

Among the popular alpha-blockers used for prostatitis, three drugs can be distinguished: alfuzosin, tamsulosin and doxazosin.

Tamsulosin is a selective alpha1-adrenergic antagonist that blocks alpha1-adrenergic receptors in the smooth muscle of the prostate and bladder neck. This drug helps reduce resistance in the urinary canal and improves urination.

Doxazosin is a drug that reduces urinary tube resistance and normalizes urine flow. It also relieves spasms of the smooth morphology of the lower urinary tract sphincters.

Tamsulosin

Tamsulosin is a selective alpha-1 blocker used in the treatment of prostatitis. This drug relaxes the smooth muscles of the prostate and bladder neck, which improves the symptoms of prostatitis.

Tamsulosin is one of the most effective drugs in the treatment of prostatitis. It reduces bladder hypertonicity and improves urination. Due to its mechanism of action, the drug relieves the symptoms of prostatitis, such as painful urination, frequent urination and weak urine flow.

The drug is taken orally once a day, usually in the evening. The initial dose and further correction are determined by the doctor depending on the severity of the disease and the individual characteristics of the patient. It is important to strictly follow the recommendations of the doctor and not to exceed the recommended dose of the drug.

Before taking tamsulosin, you should consult your doctor, as uncontrolled use of the drug can cause serious side effects and worsen the patient’s condition. In addition, the drug has a number of contraindications that must be considered before prescribing it.

Sildenafil

Sildenafil is one of the best known drugs for the treatment of erectile dysfunction. It belongs to the group of phosphodiesterase 5 inhibitors (PDE-5) and acts on the body, increasing blood flow to the genitals. Thus, it helps to achieve and maintain an erection.

Sildenafil is widely used in medical practice for the treatment of erectile dysfunction and is highly effective. The drug is taken orally, usually 30-60 minutes before the planned sexual intercourse. The dosage depends on the specific situation and can be individually selected by the doctor.

However, it should be remembered that sildenafil is not a drug against prostatitis. It is not able to treat the underlying cause of the disease and has no direct effect on the prostate. However, in some cases, the use of sildenafil can improve the quality of a man’s sexual life, which has a positive effect on his general condition and well-being.

Finasteride

Finasteride is a 5-alpha reductase inhibitor drug used to treat prostatitis in men. It is an effective remedy for improving the condition of the prostate and reducing the symptoms of the disease.

The main active ingredient of finasteride is a specific inhibitor of 5-alpha reductase, an enzyme that converts testosterone to dihydrotestosterone. This process is one of the reasons for the development of prostatitis, since an increased level of dihydrotestosterone leads to prostate hypertrophy and compression of the urethra.

The drug is taken orally and has a high bioavailability. It is usually taken once a day, the duration of therapy depends on the severity of the disease and the recommendations of the doctor. However, before you start taking finasteride, you should consult your doctor and undergo regular medical supervision.

The drug is usually well tolerated by most patients, but may cause some side effects, including decreased sexual activity and sexual desire, erectile dysfunction, male breast enlargement, and others. If any side effects occur, you should immediately consult your doctor.

Dutasteride

Dutasteride is a type of alpha blocker used to treat prostatitis. Its action is aimed at increasing the urinary flow and improving the condition of the prostate.

Dutasteride is taken as a tablet as directed by a physician. It has a prolonged action, so it is enough to take it once a day.

The drug affects the hormonal balance in the body. It blocks the activity of the 5-alpha reductase enzyme, which causes testosterone to be converted to dihydrotestosterone, the hormone responsible for prostate enlargement.

Dutasteride helps reduce inflammation in the prostate gland, improves urine flow and reduces the frequency of nighttime urination. It helps to relieve the symptoms of prostatitis, such as pain, burning and discomfort.

Terazosin

Terazosin is an alpha blocker used to treat the symptoms of prostatitis. The main active ingredient of this drug is terazosin hydrochloride.

Terazosin reduces resistance in the prostatic part of the urinary tract, as well as in the sphincters of the bladder neck. This makes the process of urination freer and improves hemodynamics in the prostate.

The drug does not have a direct effect on the prostate itself, but it can significantly reduce discomfort and symptoms such as painful urination, feeling of an incomplete bladder and pain in the perineum.

Terazosin is usually taken by mouth once a day, with or without food. The initial dose is usually small to avoid possible side effects, and gradually increased under the supervision of a physician. The course of treatment can last several weeks or months, depending on the severity of the symptoms and the individual patient.

Some of the side effects that may occur with terazosin include drowsiness, dizziness, headache, impaired ejaculation, and a temporary decrease in blood pressure. Before you start taking terazosin, you should check with your doctor to make sure this drug is safe for you and will not cause unwanted effects.

Alfuzosin

Alfuzosin is one of the most effective alpha-blockers used to treat prostatitis. It belongs to the group of selective α1-adrenergic receptor antagonists.

The main goal of treating prostatitis is to relieve symptoms and improve the patient’s quality of life. Alfuzosin is able to cope with such manifestations of the disease as urination disorders, pain and dysuria.

Alfuzosin blocks α1-adrenergic receptors, which are located in the muscles of the bladder neck and prostate. Due to this mechanism of action, there is a decrease in the tone of smooth muscles, the expansion of the lumen of the urethra and the facilitation of urination.

The drug is taken orally before meals, without chewing and splitting the tablet. The dosage is prescribed by the doctor depending on the severity of the symptoms and the individual characteristics of the patient. The duration of the course of therapy is also determined by the doctor.

Alfuzosin has several advantages, including few side effects and negative drug interactions. However, before you start taking alfuzosin, you should consult your doctor to determine the dosage and possible contraindications.

Silodosin

Silodosin is one of the alpha1-adrenergic antagonists used in the treatment of prostatitis. Its active ingredient silodosin hydrochloride has a specific effect on alpha1-adrenergic receptors, which are located in the smooth muscles of the prostate and bladder neck. Due to its mechanism of action, silodosin helps to relieve spasm and reduce hypertension in the smooth muscles of the prostate and bladder.

Silodosin can improve the quality of life of patients with prostatitis by reducing pain symptoms and improving urination. Silodosin also helps to normalize prostate secretion and reduce inflammation in this area.

The drug is taken orally in the form of capsules. It is recommended to take silodosin after a meal as this increases its absorption in the gut. The dosage and duration of silodosin intake are prescribed by the doctor individually for each patient, based on the characteristics of the disease and the body’s response to treatment.

It is important to note that silodosin, like any drug, has contraindications and side effects. Before starting treatment with silodosin, you should consult with a specialist and strictly follow his recommendations for taking the medication.

Doxazosin

Doxazosin is an alpha blocker that is widely used to treat prostatitis. It belongs to a group of drugs that have a positive effect on the prostate and reduce the symptoms of the inflammatory process.

Doxazosin reduces the symptoms of prostatitis, such as pain and discomfort, facilitates urination and reduces frequent urination, which improves the quality of life of patients.

It works by blocking the activity of alpha-adrenergic receptors, which are found in the muscles of the prostate and bladder neck. Due to this, Doxazosin helps to relax the smoothed muscles of the prostate and improve the flow of urine.

The drug is taken orally once a day, usually at bedtime. The dosage is prescribed by the doctor, based on the severity of the disease and the individual characteristics of the patient.

It is important to note that doxazosin may cause some side effects such as dizziness, weakness, drowsiness, ejaculatory disturbance and excessive flushing of the face. Therefore, before starting treatment, it is necessary to consult a doctor.

Mirabegron

Mirabegron is a beta-3-adrenergic agonist that activates β3-adrenergic receptors in the bladder. This mechanism of action allows mirabegron to improve the symptoms of reduced ureteral function and urogenital disorders.

Mirabegron is recommended for patients with symptoms of urinary incontinence, increased urinary frequency and urogenital disorders associated with physical exertion. It improves urinary control and reduces the frequency of urination.

Mirabegron regulates urination by improving the functioning of the bladder and contracting its muscles, which increases its capacity and reduces its sensitivity to irritants. This drug also helps to relax the muscles of the bladder neck, which reduces the risk of urinary incontinence.

Mirabegron is available as tablets to be taken by mouth as directed by a doctor. The initial recommended dose is 25 mg per day and may be increased to 50 mg per day if needed. However, the dosage may vary depending on the patient and his individual characteristics. Before starting treatment, it is recommended to consult a doctor and strictly follow his recommendations for dosage and intake.

Bisoprolol

Bisoprolol is a drug from the group of beta-blockers, which is widely used in cardiology for the treatment of cardiovascular diseases. Stimulates the receptors of the adrenergic system and blocks their action, which reduces the heart rate, lowers blood pressure and improves blood supply to organs.

For prostatitis, bisoprolol can be used to relieve symptoms of prostate inflammation. Its effect on the adrenergic system can reduce inflammation and improve microcirculation in the prostate. In addition, bisoprolol helps to reduce pain and discomfort in the prostate area.

The drug is taken orally in the form of tablets of 5 or 10 mg per day. The dosage is determined by the doctor and depends on the individual characteristics of the patient. Bisoprolol has a high degree of safety when used correctly, however, it can cause unwanted side effects such as fatigue, dizziness, and sleep disturbances. When they appear, you should consult your doctor.

In combination with other drugs, alpha-blockers for prostatitis, bisoprolol can have a more pronounced and effective effect on the condition of the pelvic organs and improve the patient’s general well-being.

Methods of administration

Alpha-blockers for prostatitis are taken orally, in the form of tablets or capsules. To achieve the best effect, it is recommended to take the drugs at the same time every day.

The dosage of drugs may depend on the individual characteristics of the body and the severity of the disease. The usual starting dose is 1 tablet per day. If necessary, the doctor may increase the dose to 2 or 3 tablets per day.

Treatment with alpha-blockers for prostatitis should be carried out under the supervision of a physician, who will determine the duration of the course of treatment. Usually drugs are taken within 2-3 weeks.

While taking alpha-blockers, moderate physical activity is recommended to improve blood circulation and metabolism in the pelvic organs. You should also avoid hypothermia and stressful situations that can aggravate the symptoms of prostatitis.

Also, during the treatment of prostatitis, it is important to monitor your diet. It is recommended to exclude from the diet spicy, fried and fatty foods, as well as the use of alcohol and strong coffee.

Related videos:

Q&A:

What medications can be used for prostatitis?

Alpha-blockers – one of the groups of drugs that are used for prostatitis. They help reduce muscle tension and improve blood flow to the prostate gland, which alleviates the symptoms of the disease. Some of the effective drugs in this group include terazosin, doxazosin, tamsulosin, and alfuzosin.

Which of the alpha-blockers is the most effective?

The most effective drugs from the group of alpha-blockers in the treatment of prostatitis are tamsulosin (trade name Flomax) and alfuzosin (trade name Urokinase). They are highly effective in improving the symptoms of prostatitis and have minimal side effects.

Omnik: instruction, price, analogues | modified release hard capsules Astellas Pharma Europe

• Pharmacological properties
• Readings Omnic
• Application Omnic
• Contraindications
• Side effects
• Special instructions
• Interactions
• Overdose
• Storage conditions
• Diagnosis
• Recommended alternatives
• Trade names

pharmacodynamics. Omnic selectively and competitively blocks postsynaptic α ₁ -adrenergic receptors, in particular α _1A and α _1D , located in the smooth muscles of the prostate, bladder neck and prostatic urethra. This leads to a decrease in the tone of the smooth muscles of the prostate gland, the neck of the bladder and the prostate part of the urethra and an improvement in the outflow of urine. At the same time, it reduces the severity of symptoms of obstruction and irritation caused by benign prostatic hyperplasia (difficulty starting urination, weakening the urine stream, dripping after urination, a feeling of incomplete emptying of the bladder, frequent urge to urinate, urge to urinate at night, imperative urge to urinate) .

These effects persist for a long time with long-term treatment and greatly discourage surgery or catheterization.

Antagonists α ₁ -adrenergic receptors have the ability to reduce blood pressure by reducing peripheral vascular tone. When conducting studies of the drug Omnik, there was no clinically significant decrease in blood pressure.

Pharmacokinetics. Absorption : Tamsulosin is well absorbed from the gastrointestinal tract, and its bioavailability is almost 100%. Absorption of tamsulosin occurs somewhat more slowly after a meal. Homogeneity of absorption is achieved when the patient uses Omnic at the same time after a meal. The pharmacokinetics of tamsulosin is linear.

After taking a single dose of the drug Omnic after a meal C _max tamsulosin in blood plasma is reached after about 6 hours, and a stable concentration – on the 5th day after daily administration of the drug. C _max is approximately ⅔ higher than that achieved after taking a single dose.

Distribution: in men, tamsulosin is approximately 99% bound to plasma proteins. The volume of distribution of the drug is insignificant (about 0.2 l / kg).

Metabolism: tamsulosin hydrochloride is not subject to the first pass effect and is slowly metabolized in the liver to form pharmacologically active metabolites that retain high selectivity for α ₁ -adrenergic receptors. Most of the active substance is present in the blood unchanged.

Elimination: tamsulosin and its metabolites are excreted primarily in the urine. About 9% of the dose remains in the form of unchanged active substance.

After a single dose of the drug Omnic after meals and at a stable plasma concentration T _½ is approximately 10 and 13 hours, respectively.

treatment of functional disorders of the lower urinary tract in benign prostatic hyperplasia.

The recommended adult dose is 1 capsule per day after breakfast daily or after the first meal. The capsule should be swallowed whole and not broken or chewed as this will prevent the modified release of the active ingredient.

Dose adjustment is not required in patients with renal insufficiency. Dose adjustment is not required in patients with moderate to moderate hepatic impairment (see CONTRAINDICATIONS).

hypersensitivity to tamsulosin hydrochloride, including drug-induced angioedema, or to any of the excipients; a history of orthostatic hypotension; severe liver failure.

*Noted in the post-registration period.

There have been post-marketing reports of intraoperative iris instability (constricted pupil syndrome) during cataract and glaucoma surgery in patients treated with tamsulosin (see SPECIAL INSTRUCTIONS).

Post-marketing experience : in addition to the above adverse reactions, cases of atrial fibrillation, arrhythmia, tachycardia and dyspnoea have been reported. Since these reports were spontaneous in nature, their frequency and the role of tamsulosin cannot be reliably established.

As with the use of other blockers α ₁ -adrenergic receptors, in some cases, when using Omnic, a decrease in blood pressure is possible, which can sometimes lead to loss of consciousness. When the first signs of orthostatic hypotension (dizziness, weakness) appear, the patient should take a horizontal position until the above symptoms disappear.

Before starting treatment with Omnic, a medical examination should be performed to look for other comorbid conditions that may cause the same symptoms as benign prostatic hyperplasia. Before starting treatment, a rectal examination of the prostate gland and, if necessary, a prostate specific antigen (PSA) test should be performed before and at regular intervals during treatment.

Prescribe the drug to patients with severe renal insufficiency (creatinine clearance <10 ml / min) with extreme caution, since clinical studies with the use of the drug Omnic in such patients have not been conducted.

Some patients who have taken or are taking tamsulosin have experienced atonic pupil syndrome (a variant of constricted pupil syndrome) during cataract and glaucoma surgery, which may increase the number of complications during such surgery.

It is generally recommended to stop tamsulosin treatment 1-2 weeks before cataract and glaucoma surgery. However, the feasibility and timing of discontinuation of tamsulosin treatment has not yet been clearly established. Atonic pupil syndrome has also been reported in patients who discontinued tamsulosin for a long time prior to cataract surgery.

Initiation of tamsulosin hydrochloride is not recommended in patients prior to elective cataract or glaucoma surgery. In preparation for surgery, surgeons and ophthalmologists should be informed whether the patient has taken (or is taking) tamsulosin in order to prevent possible complications associated with atonic pupil syndrome.

Tamsulosin hydrochloride should not be used in combination with strong CYP3A4 inhibitors in patients with low CYP2D6 metabolism.

Tamsulosin hydrochloride should be used with caution in combination with strong and moderate CYP 3A4 inhibitors (see INTERACTIONS).

Cases of allergic reactions to tamsulosin have been reported in patients with a history of allergy to sulfonamides. Caution should be exercised when using tamsulosin hydrochloride in patients who have previously been allergic to sulfonamides.

Use during pregnancy and lactation. The drug is used only for the treatment of men.

Fertility. Ejaculatory disturbances have been observed in short and long term clinical trials with tamsulosin. Cases of impaired ejaculation, retrograde ejaculation and insufficient ejaculation were recorded in the post-registration period.

Children. The drug is not used in children.

The ability to influence the reaction rate when driving vehicles or working with other mechanisms . Studies of the effect of the drug on the ability to drive vehicles or operate other mechanisms have not been conducted. However, patients should be warned about the possibility of dizziness.

Interaction studies have been conducted in adults only.

When tamsulosin hydrochloride was co-administered with atenolol, enalapril or theophylline, no drug interactions were noted. Simultaneous use with cimetidine increases, and with furosemide – reduces the concentration of tamsulosin in the blood plasma, but since these levels remain within the normal range, there is no need for a special dose adjustment of tamsulosin.

In vitro studies diazepam, propranolol, trichlormethiazide, chlormadinone, amitriptyline, diclofenac, glibenclamide, simvastatin and warfarin do not affect the free fraction of tamsulosin in human plasma. Similarly, tamsulosin does not alter the free fractions of diazepam, propranolol, trichlormethiazide, and chlormadinone in human plasma.

However, diclofenac and warfarin may increase the elimination rate of tamsulosin.

Concomitant use of tamsulosin hydrochloride with strong inhibitors of CYP 3A4 may increase the effect of tamsulosin hydrochloride. Simultaneous use with ketoconazole (a known potent inhibitor of CYP 3A4) led to an increase in AUC and an increase in C _max to 2.8 and 2.2 respectively.

Tamsulosin hydrochloride should not be used in combination with strong CYP3A4 inhibitors in patients with low CYP2D6 metabolism.

The drug should be used with caution in combination with strong and moderate inhibitors of CYP 3A4.

Simultaneous use of tamsulosin hydrochloride and paroxetine (a powerful inhibitor of CYP 2D6) leads to an increase in C _max and an increase in AUC to 1.3 and 1.6, respectively, but this is not clinically significant.

Simultaneous use with other blockers α ₁ -adrenergic receptors may enhance the hypotensive effect.

symptoms . An overdose of tamsulosin can potentially cause a severe hypotensive effect. Severe hypotensive effect was noted at various degrees of overdose.

Treatment . In the event of a sharp decrease in blood pressure due to an overdose, maintenance therapy should be carried out aimed at restoring the normal function of the cardiovascular system (for example, the patient should take a horizontal position). If this measure does not work, it is necessary to carry out infusion therapy and prescribe vasopressors. Renal function should be monitored and general supportive therapy administered. Due to the high degree of binding of tamsulosin to plasma proteins, hemodialysis is hardly advisable.